compared to rg = −0.54 for the primary ADHD GWAS; approximate P = 1.1 × 10−9 for difference) and other education-related phenotypes. Genetic correlations with obesity-related phenotypes were similarly smaller for the 23andMe cohort. The one domain where 23andMe exhibited a trend toward stronger genetic correlations were schizophrenia (rg = 0.27, vs. rg = 0.12 in ADHD, P = 0.053) and bipolar disorder (rg = 0.029, vs. rg = 0.095 in ADHD, P = 0.09), though these trends are not significant with the approximated test of the difference in genetic correlation.
