and adventurousness. The top SNP for PCDH7 (rs13138213; P = 1.44E–06) is in strong LD (r2 > 0.8) with a small number of other closely located SNPs and the signal for the gene-based test appears to be driven by two independent loci (Supplementary Fig. 4). IPO13 codes for a nuclear transport protein. IPO13 has been implicated in the UKB GWASs on whether a person holds a college or university degree and intelligence. The top SNP (rs3791116; P = 1.19E–05) is in moderate-to-strong LD with multiple SNPs (Supplementary Fig. 5), including SNPs in the neighboring ST3GAL3 gene.
