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Chunk #15 — RESULTS — Biological Annotation

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Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.
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There are also many novel findings associated with the large number of genes newly implicated by our analyses: At the standard false discovery rate (FDR) threshold of 5%, the bioinformatics tool DEPICT19 prioritizes 1,838 genes (Supplementary Table 7), a tenfold increase relative to the DEPICT results from an earlier GWAS of EduYears10. In what follows, we distinguish between the 1,703 “newly prioritized” genes and the 135 “previously prioritized” genes.