To confirm that control and SZ hiPSC NPCs were comparably patterned, we specifically compared expression of 74 well-accepted markers of neural subtype identity in control and SZ NPCs and neurons (Supplementary Figure 2 and Supplementary Table 2). Of the 15/74 genes with perturbed expression, only four (NEUROD1, MATH3, HOXB9 and FOXO1) were transcription factors, and of the others, six were synaptic genes, one was the extracellular matrix gene RELN, and three were enzymes involved in the synthesis of gamma-aminobutyric acid or dopamine (Supplementary Figure 2 and Supplementary Table 2).
