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Chunk #27 — Results — Functional Connectivity Analysis — Connectivity in Default Mode Network

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Functional and Structural Alteration of Default Mode, Executive Control, and Salience Networks in Alcohol Use Disorder.
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Compared to the healthy group, the AUD group showed increased connectivity in (1) the right hippocampus—right angular cortex (t = 3.28, P < 0.05); (2) right hippocampus—left hippocampus (t = 2.91, P < 0.05); and (3) left hippocampus—right angular cortex (t = 2.92, P < 0.05) of the dorsal DMN (Table 2; Supplementary Figure 3). In the ventral DMN, the right angular gyrus and middle occipital gyrus—left middle frontal gyrus connection (t = −3.40, P < 0.05) had increased and (1) right superior frontal gyrus and middle frontal gyrus—right parahippocampal gyrus (t = 3.34, P < 0.05); (2) right parahippocampal gyrus—right angular gyrus and middle occipital gyrus (t = 3.09, P < 0.05) had decreased in the AUD group (Table 2; Supplementary Figure 4).