Studies have reported that the complement system is activated in ALD and participates in different stages of its pathogenesis, including alcoholic fatty liver disease (AFLD), alcoholic hepatitis (AH), alcoholic hepatic fibrosis, and cirrhosis (Table 1) [21-23]. In this mini-review, the role and mechanism of the complement system in different stages of ALD are briefly summarized, especially focusing on the recent relevant progress.
