Note that the precise allocation of responsibilities between primary research or collection sites and biobanks will vary by the design of the biobank research system. Suggesting that biobanks themselves should have some responsibilities for determining whether and how to return IFs and IRRs in a biobank research system does not mean that the biobank should have full responsibility and the primary researchers none. Coordination between primary researchers or collection sites and the biobank will be necessary, including coordination between their IRBs. As already noted, re-identification of contributor(s) may rest at the primary research site, biobank, at both, or with a trusted intermediary. Moreover, responsibilities for recontact may often best remain with the primary researcher or collection site. The primary researchers may, in some research designs, have ongoing contact with the contributor and thus be best suited to perform any recontact. However, recognizing that the biobank does bear some of the responsibilities for addressing IFs and IRRs in the biobank research system and for performing some of the specific functions involved has the potential to advance consistency, reliable performance of duties,
