Additionally, we examined rs7341475, a SNP proposed in this same study as a female-specific risk factor, in just the females from our study (n = 275 cases and 361 controls) and found no association (p = 0.24). Finally, a recent whole genome association study of schizophrenia [17] found that one polymorphism, rs4129148, achieved genome wide significance and a second associated common polymorphism, rs28414810, was in one of the nearest genes [17], both located in the pseudoautosomal region of chromosomes X and Y. As in the original paper, we tested the SNPs separately in males and females, but could find no evidence of association in males or females of either cohort using either an additive or a recessive model.
