The third gene, SCOC, encodes a short coiled-coil domain-containing protein that localizes to the Golgi apparatus. Many coiled-coil-type proteins are involved in important biological functions such as the regulation of gene expression through the regulation of transcription factor binding.62 The function of SCOC is largely unknown and no previous association studies have linked SCOC to cannabis or other substance use phenotypes. The SCOC antisense RNA1 gene is located in the same chromosomal region.
