The UKB has set an excellent standard for linking genomic and phenotypic data and its dynamic nature will facilitate new opportunities for genetic discovery. In future studies, phenotypes may be refined through combining binary, phenotypic and temporal data. The results of this PheWAS are publicly available (http://azphewas.com/), which we anticipate will help to elucidate disease mechanisms, identify phenotypic expansions and enable the development of human genetically validated drugs.