The CI treatment utilized 11 treated and 10 control animals and employed similar conditions to those used for the Chronic study, except that ethanol was only available every other day. On days that ethanol was available, bottle positions were alternated to control for position preference. Mice were approximately 3 months old at the beginning of experiments. The total duration of the CI experiment was determined by the total amount of ethanol consumed, which was matched with the total amount of ethanol consumed in the Chronic paradigm. In the Chronic drinking paradigm, the average total ethanol intake for all mice was 406 g/kg. Thus, the CI study was concluded when the average total ethanol intake for all mice reached a similar level: 409 g/kg after 29 days of drinking. Since these animals only had access to ethanol every other day, the total length of the study, including drinking and non-drinking days, was 57 days. CI animals were maintained on a 12∶12 light/dark light cycle (lights on at 07∶00 AM). Control animals received only water. Data from all animals was used for
