dysfunction observed in the group of conditions which we collectively refer to as schizophrenia. The most important among these areas which are linked to the FSC through open connections is the temporo-limbic cortex. The connections between the temporo-limbic cortex and PFC are mediated through white fiber connections originating from the frontal pole (FP) and projected to the superior temporal gyrus (STG) through the extreme capsule and the amygdala through the uncinate fasciculus[9]; the FP is also connected to the anterior cingulate cortex through the cingulate fasciculus.[9] Therefore, it is presumed that an inquiry into the links between the FSC and temporo-limbic circuitry dysfunction and the symptom dimensions and neurocognitive dysfunction noted in schizophrenia could provide vital clues in understanding the underlying pathophysiology of this enigmatic condition.
