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Chunk #18 — Results — Functional Connectivity Analysis — Edge-Wise Functional Connectivity

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General and specific functional connectivity disturbances in first-episode schizophrenia during cognitive control performance.
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One connected component, comprising seven edges connecting eight regions, demonstrated a significant cue-by-diagnosis interaction (p = .042, corrected; Figure 4, top right). Approximately two thirds of these involved frontal regions: 29% were frontofrontal and 29% were frontoparietal. For each edge, control subjects showed a B cue > A cue task effect on connectivity, whereas patients showed the reverse pattern (Figure S3 in Supplement 1). These findings were not significant for k = .01 or k = .001.