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Chunk #16 — Results — Functional Connectivity Analysis — Edge-Wise Functional Connectivity

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General and specific functional connectivity disturbances in first-episode schizophrenia during cognitive control performance.
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To better understand the regional distribution of these connections, we classified each region as belonging to one of five broad lobar subgroupings: frontal, temporal, parietal, occipital, or subcortical. We then categorized each edge in the affected subnetwork on the basis of the lobes they connected (e.g., frontotemporal, temporoparietal, etc.) and counted the proportion of edges falling into each category. Most connections showing a significant effect of cue were frontotemporal (36%) or temporosubcortical (25%; Figure 4, bottom left). Similar findings were obtained across different values of K (Figure S2 in Supplement 1).