Induced pluripotent stem cell technology: a decade of progress.
paper
Cited
Public
- Authors
- Shi, Yanhong; Inoue, Haruhisa; Wu, Joseph C; Yamanaka, Shinya
- Year
- 2017
- Journal
- Nature reviews. Drug discovery
- PMID
- 27980341
- DOI
- 10.1038/nrd.2016.245
- PMCID
- PMC6416143
Since the advent of induced pluripotent stem cell (iPSC) technology a decade ago, enormous progress has been made in stem cell biology and regenerative medicine. Human iPSCs have been widely used for disease modelling, drug discovery and cell therapy development. Novel pathological mechanisms have been elucidated, new drugs originating from iPSC screens are in the pipeline and the first clinical trial using human iPSC-derived products has been initiated. In particular, the combination of human iPSC technology with recent developments in gene editing and 3D organoids makes iPSC-based platforms even more powerful in each area of their application, including precision medicine. In this Review, we discuss the progress in applications of iPSC technology that are particularly relevant to drug discovery and regenerative medicine, and consider the remaining challenges and the emerging opportunities in the field.
A schematic for human iPSC-based disease modeling. Human iPSCs are derived from individual patients and differentiated into specific cell types. To develop new therapies, the resultant cells are used to observe disease-specific phenotypes and identify novel pathological mechanisms,. Human iPSC-based disease modeling with patient-specific cells now provides an exciting new approach for the development of personalized diagnosis and medicine.
A schematic for human iPSCs-based cell therapy. Human iPSC-based cell therapy development usually includes the following steps: 1) Collect somatic cells from patients and culture somatic cells from affected patients; 2) Reprogram patient somatic cells into iPSCs; 3) Use genome editing technology or viral transduction method to repair patient iPSCs and turn them into genetically corrected iPSCs; 4) Differentiate the corrected iPSCs into desired cell types to serve as genetically matched healthy donor cells; 5) Perform quality control test for cell identity, purity, activity, and safety; and 6) Transplant the genetically matched healthy cells into patients for cell therapy.
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In this knowledge base
| Title | Year | PMID |
|---|---|---|
| Genetics of Alcohol Use Disorder: A Role for Induced Pluripotent Stem Cells? | 2018 | 29897633 |
External
| Title | Authors | Journal | Year | Link |
|---|---|---|---|---|
| ABE9 fused to SpRY Cas9 nickase enables precise generation of bystander free mouse models. | Ong JK et al. | β | 2026 | β |
| A Method to Enrich Functional Human Paneth Cells in Induced Pluripotent Stem Cell-Derived Intestinal Organoids. | Patel S et al. | β | 2026 | β |
| Clinical and functional evidence supporting the pathogenicity of the novel <i>PSEN1</i> p.R358P variant in early-onset Alzheimer's disease. | GarcΓa-Chialva DE et al. | β | 2026 | β |
| Current Advances and Applications of Retinal Organoids. | Zhou DN et al. | β | 2026 | β |
| Defective autophagy in GNE myopathy is rescued by inhibition of noncanonical Akt-mTORC1 activation across multiple isogenic models. | Kim DW et al. | β | 2026 | β |
| Drug discovery research with iPSC models of neurodegenerative diseases. | Adachi M et al. | β | 2026 | β |
| Exploring Patient Organization Involvement in Stem Cell Research: Insights from the Lifeworld. | Lopes E et al. | β | 2026 | β |
| From 3D culture to clinical decision-making: Systematic innovations in breast cancer organoids. | Hu M et al. | β | 2026 | β |
| Gene Expression at the Pluripotency Stage Predicts Pancreatic Endocrine Differentiation in iPSC Clones. | Zamarian V et al. | β | 2026 | β |
| Generation and characterization of iPSC models from HIV-1-positive individuals with divergent clinical outcomes. | Almeida N et al. | β | 2026 | β |
| Generation of two Induced pluripotent stem cell lines from umbilical Cord-Derived mesenchymal stem cells. | Cheng Y et al. | β | 2026 | β |
| Human bone marrow niche organoids for disease modeling and therapeutic application in hematopoietic syndrome. | Park H et al. | β | 2026 | β |
| Human iPSC-derived neural progenitor cells rescue motor function and brain pathology in symptomatic Canavan disease mice. | Jackson N et al. | β | 2026 | β |
| Lentiviral Vector-Mediated Gene Delivery for iPSC-Related Neuroscience Research. | Okunomiya T et al. | β | 2026 | β |
| Magnetically controlled microgelbots with stem cells for the treatment of interstitial cystitis. | Choi H et al. | β | 2026 | β |
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| Poking Pluripotency: Nanoinjection Into Human iPSCs. | Harberts J et al. | β | 2026 | β |
| Reimagining human-centric drug development with new approach methodologies. | Wu X et al. | β | 2026 | β |
| Synthetic rewriting technologies in mammalian cells. | Wang Y et al. | β | 2026 | β |
| Telomerase-active urine-derived stem cells: Regenerative solutions for aging. | Cheng X et al. | β | 2026 | β |
| Therapeutic Targets and Signaling Mechanisms in 2D and 3D InΒ Vitro Models of Osteoarthritis. | Suresh D et al. | β | 2026 | β |
| Unraveling the Genetic Mysteries of MΓΌllerian Anomalies: Research Approaches and Clinical Significance. | Li J et al. | β | 2026 | β |
| Unraveling the Morphological and Functional Maturation Mechanisms Underlying Human Neural Development Using iPSCs-Derived Neuronal Model. | Tian Y et al. | β | 2026 | β |
| Valproic acid as a therapeutic scaffold: Advances in structural modification and drug design. | Trocha A et al. | β | 2026 | β |
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| Addressing graft-versus-host disease in allogeneic cell-based immunotherapy for cancer. | Lyu Z et al. | β | 2025 | β |
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| Advances in the Development and Application of Human Organoids: Techniques, Applications, and Future Perspectives. | Zhu Z et al. | β | 2025 | β |
| Advantages and challenges of ex vivo generation and expansion of human hematopoietic stem cells from pluripotent stem cells. | Ding M et al. | β | 2025 | β |
| Age-Related Macular Degeneration: Therapeutic Strategies Based on Stem Cells. | Mathivanan I et al. | β | 2025 | β |
| A Guided Approach to Establish a Functional Humanized Brain-on-a-Chip Microfluidic Model of the Neurovascular System. | Raut S et al. | β | 2025 | β |
| A gut-on-a-chip incorporating human faecal samples and peristalsis predicts responses to immune checkpoint inhibitors for melanoma. | Ballerini M et al. | β | 2025 | β |
| A high-performance extracellular field potential analyzer for iPSC-derived cardiomyocytes. | Patel N et al. | β | 2025 | β |
| AI-guided Cas9 engineering provides an effective strategy to enhance base editing. | Wei D et al. | β | 2025 | β |
| An NGS-based approach for precise and footprint-free CRISPR-based gene editing in human stem cells. | Vandendriessche B et al. | β | 2025 | β |
| A protocol for karyotyping and genetic editing of induced pluripotent stem cells with homology-directed repair mediated CRISPR/Cas9. | Lobo S et al. | β | 2025 | β |
| A Roadmap of Peptide-Based Materials in Neural Regeneration. | Tsai YL et al. | β | 2025 | β |
| Artificial intelligence and systems biology analysis in stem cell research and therapeutics development. | Silva-Sousa T et al. | β | 2025 | β |
| Biallelic genome engineering to create isogenic induced pluripotent stem cells modeling Huntington's disease. | Kurasawa H et al. | β | 2025 | β |
| Biological Barrier Models-on-Chips: A Novel Tool for Disease Research and Drug Discovery. | Caragnano G et al. | β | 2025 | β |
| Biomaterial platforms in cardiovascular regenerative medicine - challenges and future perspectives. | Vo QD | β | 2025 | β |
| Biomaterials and cell-based therapy post spinal cord injury. | Haratizadeh S et al. | β | 2025 | β |
| Cell therapy for liver disorders: past, present and future. | OrtuΓ±o-Costela MC et al. | β | 2025 | β |
| Comparative CRISPRi screens reveal a human stem cell dependence on mRNA translation-coupled quality control. | Rodschinka G et al. | β | 2025 | β |
| Controlling CRISPR-Cas9 genome editing in human cells using a molecular glue degrader. | Khajanchi N et al. | β | 2025 | β |
| CRISPR-Cas9 mediated knockout of NDUFS4 in human iPSCs: A model for mitochondrial complex I deficiency. | Goolab S et al. | β | 2025 | β |
| Cullin-RING Ubiquitin Ligases in Neurodevelopment and Neurodevelopmental Disorders. | Ashitomi H et al. | β | 2025 | β |
| Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics. | Kim M et al. | β | 2025 | β |
| Deciphering the physiopathology of neurodevelopmental disorders using brain organoids. | Dionne O et al. | β | 2025 | β |
| Decoding human chemical reprogramming: mechanisms and principles. | Cheng L et al. | β | 2025 | β |
| Decoding Liver Fibrosis: How Omics Technologies and Innovative Modeling Can Guide Precision Medicine. | Codotto G et al. | β | 2025 | β |
| Decoding microglial functions in Alzheimer's disease: insights from human models. | Rao C et al. | β | 2025 | β |
| Dimethyl Sulfoxide Conditions Induced Pluripotent Stem Cells for more Efficient Nephron Progenitor and Kidney Organoid Differentiation. | Kearney H et al. | β | 2025 | β |
| Direct reprogramming of mouse fibroblasts into self-renewable alveolar epithelial-like cells. | Morita A et al. | β | 2025 | β |
| Disruption of cTnT-Mediated Sarcomere-Mitochondrial Communication Results in Dilated Cardiomyopathy. | Ye L et al. | β | 2025 | β |
| Distal lung organoids derived from adult stem cells as novel tools in deciphering mechanisms of lung regeneration, infection, and cancer. | Bell M et al. | β | 2025 | β |
| DNA and Graphene-Based Nanomaterial Applications in Stem Cell Therapeutics and Regeneration. | Prakash G et al. | β | 2025 | β |
| Dual prophylactic and therapeutic potential of iPSC-based vaccines and neoantigen discovery in colorectal cancer. | Jwo SH et al. | β | 2025 | β |
| Effect of Bioactive Glass into Mineral Trioxide Aggregate on the Biocompatibility and Mineralization Potential of Dental Pulp Stem Cells. | Kim HG et al. | β | 2025 | β |
| Effect of Octacalcium Phosphate on Osteogenic Differentiation of Induced Pluripotent Stem Cells in a 3D Hybrid Spheroid Culture. | Sugai Y et al. | β | 2025 | β |
| Electrical impedance sensing in stem cell research: Insights, applications, and future directions. | Moghtaderi H et al. | β | 2025 | β |
| Engineered iPSC-derived natural killer cells: recent innovations in translational innate anti-cancer immunotherapy. | Sun J et al. | β | 2025 | β |
| Estradiol alleviates disease phenotypes caused by m.3635GΒ >Β A mutation by activating mitochondrial biogenesis and PINK1-Parkin mediated mitophagy in iPSC-derived retinal pigment epithelium cells. | Hu C et al. | β | 2025 | β |
| Evaluation of Induced Pluripotent Stem Cell-Derived Dopaminergic Neurons from Siblings with Gaucher Disease Discordant for Parkinsonism. | Hertz E et al. | β | 2025 | β |
| Excessive autophagic degradation of MYLK3 causes sunitinib-induced cardiotoxicity. | Pan Z et al. | β | 2025 | β |
| Experimental dissection of tuberculosis protective immunity: a human perspective. | Schmidiger S et al. | β | 2025 | β |
| FKBP5 Regulates Osteogenesis of Human iPSC-Derived Mesenchymal Stem Cells via FKBP5-AKT-FOXO1 Pathway. | Tian XY et al. | β | 2025 | β |
| Frontier progress and translational challenges of pluripotent differentiation of stem cells. | Su Z et al. | β | 2025 | β |
| Functional regeneration strategies of hair follicles: advances and challenges. | Chu X et al. | β | 2025 | β |
| Generation of hypoimmunogenic universal iPS cells through HLA-type gene knockout. | Kim J et al. | β | 2025 | β |
| Generation of Retinal Ganglion Cells from Reprogrammed Keratocytes of Non-Glaucoma and Glaucoma Donors. | Hameed SS et al. | β | 2025 | β |
| Global Knowledge Map and Emerging Research Trends in Induced Pluripotent Stem Cells and Hereditary Diseases: A CiteSpace-based Visualization and Analysis. | Xu J et al. | β | 2025 | β |
| Global research dynamics in the induced pluripotent stem cell and diabetes: A bibliometric analysis of the past twenty years. | Wang J et al. | β | 2025 | β |
| Human induced pluripotent stem cell-derived bioengineered skeletal muscle progenitor sheet. | Aoki N et al. | β | 2025 | β |
| Human iPSC-derived microglial cells protect neurons from neurodegeneration in long-term cultured adhesion brain organoids. | Chen X et al. | β | 2025 | β |
| Human Stem Cells in Disease Modelling and Treatment: Bridging the Gap Between Bench and Bedside. | Plaza Reyes A et al. | β | 2025 | β |
| Hypoimmunogenic pluripotent stem cells: A game-changer in cell-based regenerative medicine. | Asadi-Sarabi P et al. | β | 2025 | β |
| Hypoxia and Multilineage Communication in 3D Organoids for Human Disease Modeling. | Ehab S et al. | β | 2025 | β |
| Immortality Reconsidered: Clinical Challenges at the Frontier of Plastic Surgery. | Xun H et al. | β | 2025 | β |
| Induced pluripotent stem cell-based tissue models to study malaria: a new player in the research game. | Korbmacher F et al. | β | 2025 | β |
| Influence of Microenvironmental Orchestration on Multicellular Lung Alveolar Organoid Development from Human Induced Pluripotent Stem Cells. | Ozan VB et al. | β | 2025 | β |
| Intracellular Delivery Enabled by Squeezing Mechanoporation. | Zhang G et al. | β | 2025 | β |
| iPSC-modelling reveals genetic associations and morphological alterations of oligodendrocytes in schizophrenia. | Chang MH et al. | β | 2025 | β |
| Iterative transcription factor screening enables rapid generation of microglia-like cells from human iPSC. | Liu S et al. | β | 2025 | β |
| Melatonin alleviates oxidative stress induced damage in human iPSCs harboring mtDNA 3243A>G mutation via MAPK pathway. | Pu Z et al. | β | 2025 | β |
| Microelectrode arrays cultured with in vitro neural networks for motion control tasks: encoding and decoding progress and advances. | Hua S et al. | β | 2025 | β |
| Model-guided design of microRNA-based gene circuits supports precise dosage of transgenic cargoes into diverse primary cells. | Love KS et al. | β | 2025 | β |
| Modeling intestinal epithelial function and polarity using human iPSCs under Air-Liquid interface culture. | Tanaka E et al. | β | 2025 | β |
| Modeling statin-induced myopathy with hiPSC-derived myocytes reveals that impaired proteostasis underlies the myotoxicity and is targetable for the prevention. | Zhao X et al. | β | 2025 | β |
| Morphological Characteristics and Extracellular Matrix Abnormalities in Astrocytes Derived From iPSCs of Children With Alexander Disease. | Yi H et al. | β | 2025 | β |
| Multifactorial approach is needed to unravel the maturation phases of human neurons derived from induced pluripotent stem cells. | Ben Mahmoud M et al. | β | 2025 | β |
| Multi-organ model assessment of neurotoxicity following exposure of liver spheroids to drugs. | Wu W et al. | β | 2025 | β |
| Musculoskeletal organoids: An emerging toolkit for establishing personalized models of musculoskeletal disorders and developing regenerative therapies. | Liu Y et al. | β | 2025 | β |
| Neurodevelopmental effects of omega-3 fatty acids and its combination with Methylphenidate in iPSC models of ADHD. | Walter NM et al. | β | 2025 | β |
| Oct4 Contributes to Mesodermal Differentiation by Sustaining the Proliferative Capacity of Early Mesodermal Progenitors. | Lukacheva AV et al. | β | 2025 | β |
| Optimized, Efficient Measurement of the Expression of Undifferentiated Stem Cell Markers in Human Induced Pluripotent Stem Cells (iPSCs) by Flow Cytometry. | Saware V et al. | β | 2025 | β |
| Organ-on-chip technologies: Novel tools with the potential to revolutionize osteoarthritis research and clinical development. | Paggi CA | β | 2025 | β |
| Osteochondral organoid biofabrication: construction strategies, applications and perspectives. | Fu L et al. | β | 2025 | β |
| Pluripotent stem cell-based immunotherapy: advances in translational research, cell differentiation, and gene modifications. | Lei Q et al. | β | 2025 | β |
| Pluripotent stem cell-derived cardiomyocyte transplantation: marching from bench to bedside. | Hong Y et al. | β | 2025 | β |
| Pluripotent Stem Cells: Recent Advances and Emerging Trends. | Wang AYL et al. | β | 2025 | β |
| POLR3 gene and protein expression dynamics in 4H leukodystrophy using iPSC-derived neuronal lineages. | Kok LML et al. | β | 2025 | β |
| Progress and future prospects for the surgical treatment of permanent hypoparathyroidism after thyroid surgery: a narrative review. | Zhang D et al. | β | 2025 | β |
| Promoting the adoption of best practices and standards to enhance quality and reproducibility of stem cell research. | Selfa Aspiroz L et al. | β | 2025 | β |
| Proteomics-based receptor-ligand matching enhances differentiation maturity of human-stem-cell-derived neurons. | Dimitrov D et al. | β | 2025 | β |
| Quantifying HiPSC-CM structural organization at scale with deep learning-enhanced SarcGraph. | Mohammadzadeh S et al. | β | 2025 | β |
| Real-Time Intracellular Monitoring of miRNA Dynamics during Induced Pluripotent Stem Cell Neuronal Differentiation via Plasmon-Enhanced Nanobiosensing. | Hou Y et al. | β | 2025 | β |
| Reconstruction of endocrine subtype-complete human pluripotent stem cell-derived islets with capacity for hypoglycemia protection in vivo. | Meng G et al. | β | 2025 | β |
| Reprogramming of Different Cell Lineages into Functional Ξ²-Cell Substitutes. | Dattoli AA et al. | β | 2025 | β |
| Research of <i>inΒ vivo</i> reprogramming toward clinical applications in regenerative medicine: A concise review. | Nakatsukasa Y et al. | β | 2025 | β |
| Right ventricle remodelling: from <i>in vitro</i> to <i>in vivo</i> and from simple to complex models. | da Costa Martins PA et al. | β | 2025 | β |
| Ropinirole Functions Through a Dopamine Receptor D2-Independent Mechanism to Ameliorate Amyotrophic Lateral Sclerosis Phenotypes in TARDBP-Mutant iPSC-Derived Motor Neurons. | Asano H et al. | β | 2025 | β |
| SIMPATHIC: Accelerating drug repurposing for rare diseases by exploiting SIMilarities in clinical and molecular PATHology. | van Karnebeek CDM et al. | β | 2025 | β |
| SNTA1-deficient human cardiomyocytes show shorter field potential duration and slower conduction velocity. | Dong T et al. | β | 2025 | β |
| Stem Cell-Based Approaches for Spinal Cord Injury: The Promise of iPSCs. | Zeng CW | β | 2025 | β |
| Stepwise differentiation of airway epithelial cells from human tonsil-derived mesenchymal stem cells. | Kim HY et al. | β | 2025 | β |
| Sustaining Brain Youth by Neural Stem Cells: Physiological and Therapeutic Perspectives. | Santos M et al. | β | 2025 | β |
| Synergistic potential of stem cells and microfluidics in regenerative medicine. | Rajalekshmi R et al. | β | 2025 | β |
| Tailored bioengineering and nanomedicine strategies for sex-specific healing of chronic wounds. | Mahmoudi N et al. | β | 2025 | β |
| Targeting glioblastoma using oncolytic viruses delivered by human pluripotent stem cell-derived neural progenitor cells. | Chao J et al. | β | 2025 | β |
| The formation and architecture of surface-initiated polymer brush gene delivery complexes. | Neri-Cruz CE et al. | β | 2025 | β |
| The Generation of iPSCs Expressing Interferon-Beta Under Doxycycline-Inducible Control. | Sheveleva O et al. | β | 2025 | β |
| The Generation of Two Induced Pluripotent Cell Lines from Patients with an Atypical Familial Form of Lung Fibrosis. | Al-Mutairy E et al. | β | 2025 | β |
| The impact of RAS on cell differentiation in health and disease. | Duval CJ et al. | β | 2025 | β |
| The miR-290 and miR-302 clusters are essential for reprogramming of fibroblasts to induced pluripotent stem cells. | Ye J et al. | β | 2025 | β |
| The Perspective of Using Optical Coherence Tomography in Ophthalmology: Present and Future Applications. | Vasilescu MA et al. | β | 2025 | β |
| The Use of MSCs, iPSCs, and EVs in the Repair of Human MSK Tissues: Is Ultimate Success Dependent on Developing Excellent Implant Materials as Well as Creating an Optimal Environment for Implantation? What Is the Rationale for These Choices? | Hart DA | β | 2025 | β |
| Towards the establishment of treatments for neurodegenerative diseases using human iPSCs. | Inoue H | β | 2025 | β |
| Trisomy 21 Disrupts Thyroid Hormones Signaling During Human iPSC-Derived Neural Differentiation In Vitro. | de Souza JS et al. | β | 2025 | β |
| Vascular network-inspired diffusible scaffolds for engineering functional midbrain organoids. | Cai H et al. | β | 2025 | β |
| Very small embryonic-like stem cells (VSELs) on the way for potential applications in regenerative medicine. | Thetchinamoorthy K et al. | β | 2025 | β |
| 3D organoid cultivation improves the maturation and functional differentiation of cholangiocytes from human pluripotent stem cells. | Budi NYP et al. | β | 2024 | β |
| Accelerating Diverse Cell-Based Therapies Through Scalable Design. | Peterman EL et al. | β | 2024 | β |
| Advanced biomaterials for regenerative medicine and their possible therapeutic significance in treating COVID-19: a critical overview. | Sarangi AK et al. | β | 2024 | β |
| Advancements and Practical Considerations for Biophysical Research: Navigating the Challenges and Future of Super-resolution Microscopy. | Chen H et al. | β | 2024 | β |
| Advances in stem cells treatment of diabetic wounds: A bibliometric analysis via CiteSpace. | Ma K et al. | β | 2024 | β |
| A functional mini-GDE transgene corrects impairment in models of glycogen storage disease type III. | Gardin A et al. | β | 2024 | β |
| Aligning with the 3Rs: alternative models for research into muscle development and inherited myopathies. | Mehmood H et al. | β | 2024 | β |
| A logic-incorporated gene regulatory network deciphers principles in cell fate decisions. | Xue G et al. | β | 2024 | β |
| An increase in ER stress and unfolded protein response in iPSCs-derived neuronal cells from neuronopathic Gaucher disease patients. | Pornsukjantra T et al. | β | 2024 | β |
| A Novel Recombinant Vitronectin Variant Supports the Expansion and Differentiation of Pluripotent Stem Cells in Defined Animal-Free Workflows. | Lu X et al. | β | 2024 | β |
| A scalable, spin-free approach to generate enhanced induced pluripotent stem cell-derived natural killer cells forΒ cancer immunotherapy. | Rossi GR et al. | β | 2024 | β |
| Bibliometric analysis of organoids in regenerative medicine-related research worldwide over two decades (2002-2022). | Setiawan J et al. | β | 2024 | β |
| Bioengineering vascularization. | Landau S et al. | β | 2024 | β |
| Cardiac Tissue Engineering: A Journey from Scaffold Fabrication to In Vitro Characterization. | Ketabat F et al. | β | 2024 | β |
| Cellular models in autoinflammatory disease research. | Εen B et al. | β | 2024 | β |
| Chromatin landscape dynamics during reprogramming towards human naΓ―ve and primed pluripotency reveals the divergent function of PRDM1 isoforms. | Zhou J et al. | β | 2024 | β |
| Clinical exome analysis and targeted gene repair of the c.1354dupT variant in iPSC lines from patients with PROM1-related retinopathies exhibiting diverse phenotypes. | Puertas-Neyra K et al. | β | 2024 | β |
| Clinical trials in-a-dish for cardiovascular medicine. | Wu X et al. | β | 2024 | β |
| Comparative analysis of regulations and studies on stem cell therapies: focusing on induced pluripotent stem cell (iPSC)-based treatments. | Song SJ et al. | β | 2024 | β |
| Comparative transcriptomic and phenotypic analysis of induced pluripotent stem cell hepatocyte-like cells and primary human hepatocytes. | Gandhi N et al. | β | 2024 | β |
| Comparing fabrication techniques for engineered cardiac tissue. | Hatano R et al. | β | 2024 | β |
| Comparing stem cells, transdifferentiation and brain organoids as tools for psychiatric research. | Bellon A | β | 2024 | β |
| Developing enhanced immunotherapy using NKG2A knockout human pluripotent stem cell-derived NK cells. | Qin Y et al. | β | 2024 | β |
| Direct conversion of urine-derived cells into functional motor neuron-like cells by defined transcription factors. | Nagai H et al. | β | 2024 | β |
| Directed Differentiation of Human Induced Pluripotent Stem Cells to Heart Valve Cells. | Cai Z et al. | β | 2024 | β |
| Directed Differentiation of Neurons from Human iPSCs for Modeling Neurological Disorders. | Wang C et al. | β | 2024 | β |
| DNA binding redistributes activation domain ensemble and accessibility in pioneer factor Sox2. | Bjarnason S et al. | β | 2024 | β |
| Effect of in vivo culture conditions on the proliferation and differentiation of rat adipose-derived stromal cells. | Wang C et al. | β | 2024 | β |
| Efficient Gene-Editing in Human Pluripotent Stem Cells Through Simplified Assembly of Adeno-Associated Viral (AAV) Donor Templates. | De La Cruz BM et al. | β | 2024 | β |
| Efficient generation of induced pluripotent stem cell lines from healthy donors' peripheral blood mononuclear cells of different genders. | Gao Y et al. | β | 2024 | β |
| Elimination of the extra chromosome of Dup15q syndrome iPSCs for cellular and molecular investigation. | Munezane H et al. | β | 2024 | β |
| Emerging technologies in regenerative medicine: The future of wound care and therapy. | Sharma Y et al. | β | 2024 | β |
| Endogenous tagging using split mNeonGreen in human iPSCs for live imaging studies. | Husser MC et al. | β | 2024 | β |
| Engineering Innervated Musculoskeletal Tissues for Regenerative Orthopedics and Disease Modeling. | Zhou Z et al. | β | 2024 | β |
| Enhancing regenerative potential: A comprehensive review of stem cell transplantation for sports-related neuronal injuries, with a focus on spinal cord injuries and peripheral nervous system damage. | Bingnan W et al. | β | 2024 | β |
| Enrichment of Allelic Editing Outcomes by Prime Editing in Induced Pluripotent Stem Cells. | Niwa R et al. | β | 2024 | β |
| Establishment of human pluripotent stem cell-derived cortical neurosphere model to study pathomechanisms and chemical toxicity in Kleefstra syndrome. | Balogh A et al. | β | 2024 | β |
| Evaluating the pro-survival potential of apoptotic bodies derived from 2D- and 3D- cultured adipose stem cells in ischaemic flaps. | Yu G et al. | β | 2024 | β |
| Exploiting urine-derived induced pluripotent stem cells for advancing precision medicine in cell therapy, disease modeling, and drug testing. | Yin X et al. | β | 2024 | β |
| Exposure to the antiretroviral drug dolutegravir impairs structure and neurogenesis in a forebrain organoid model of human embryonic cortical development. | LaNoce E et al. | β | 2024 | β |
| Gene editing and reprogramming of human fibroblast cells (hFBs) to human pluripotent stem cells (hiPSCs). | Zhang Z et al. | β | 2024 | β |
| Generating Homogeneous Brain Organoids from Human iPSCs. | Chen X et al. | β | 2024 | β |
| Generation of a control induced pluripotent stem cell line (SDUCHi001-A) from a healthy male donor. | Li C et al. | β | 2024 | β |
| Generation of Alzheimer's Disease Model Derived from Induced Pluripotent Stem Cells with <i>APP</i> Gene Mutation. | Kim Y et al. | β | 2024 | β |
| Give heart cells a beat: An interactive museum exhibit that synchronizes stem cell-derived cardiomyocytes to visitors' heartbeat. | Perez-Bermejo JA et al. | β | 2024 | β |
| Hallmark Molecular and Pathological Features of POLG Disease are Recapitulated in Cerebral Organoids. | Chen A et al. | β | 2024 | β |
| Heritable epigenetic changes are constrained by the dynamics of regulatory architectures. | Jose AM | β | 2024 | β |
| High-efficiency transgene integration by homology-directed repair in human primary cells using DNA-PKcs inhibition. | Selvaraj S et al. | β | 2024 | β |
| Human-Induced Pluripotent Stem Cells in Plastic and Reconstructive Surgery. | Hadzimustafic N et al. | β | 2024 | β |
| Human In Vitro Models of Neuroenergetics and Neurometabolic Disturbances: Current Advances and Clinical Perspectives. | Rogal J et al. | β | 2024 | β |
| Human iPSC and CRISPR targeted gene knock-in strategy for studying the somatic TIE2<sup>L914F</sup> mutation in endothelial cells. | Lazovic B et al. | β | 2024 | β |
| Human pluripotent stem cells as a translational toolkit in psychedelic research <i>inΒ vitro</i>. | Salerno JA et al. | β | 2024 | β |
| iMSC-mediated delivery of ACVR2B-Fc fusion protein reduces heterotopic ossification in a mouse model of fibrodysplasia ossificans progressiva. | Gao P et al. | β | 2024 | β |
| Incomplete reprogramming of DNA replication timing in induced pluripotent stem cells. | Edwards MM et al. | β | 2024 | β |
| Induced Pluripotent Stem Cells in the Era of Precise Genome Editing. | Punetha M et al. | β | 2024 | β |
| Induced pluripotent stem cells (iPSCs): molecular mechanisms of induction and applications. | Cerneckis J et al. | β | 2024 | β |
| Informing Hazard Identification and Risk Characterization of Environmental Chemicals by Combining Transcriptomic and Functional Data from Human-Induced Pluripotent Stem-Cell-Derived Cardiomyocytes. | Tsai HD et al. | β | 2024 | β |
| Interconversion of Cancer Cells and Induced Pluripotent Stem Cells. | Sarker DB et al. | β | 2024 | β |
| In Vivo Reprogramming Using Yamanaka Factors in the CNS: A Scoping Review. | Cho HE et al. | β | 2024 | β |
| iPSC-Derived Cardiomyocytes as a Disease Model to Understand the Biology of Congenital Heart Defects. | Pushpan CK et al. | β | 2024 | β |
| iPSCs as a groundbreaking tool for the study of adverse drug reactions: A new avenue for personalized therapy. | Rispoli P et al. | β | 2024 | β |
| Kidney Disease Modeling with Organoids and Organs-on-Chips. | Musah S et al. | β | 2024 | β |
| LNP-RNA-engineered adipose stem cells for accelerated diabetic wound healing. | Xue Y et al. | β | 2024 | β |
| Macrophage variants in laboratory research: most are well done, but some are RAW. | Herb M et al. | β | 2024 | β |
| Materials-based hair follicle engineering: Basic components and recent advances. | Lv Y et al. | β | 2024 | β |
| Metabolic states influence chicken retinal pigment epithelium cell fate decisions. | Perez-Estrada JR et al. | β | 2024 | β |
| Microglial APOE3 Christchurch protects neurons from Tau pathology in a human iPSC-based model of Alzheimer's disease. | Sun GG et al. | β | 2024 | β |
| Microinstrumentation for Brain Organoids. | Patel D et al. | β | 2024 | β |
| Microphysiological Blood-Brain Barrier Systems for Disease Modeling and Drug Development. | Mulay AR et al. | β | 2024 | β |
| Modeling mutation-specific arrhythmogenic phenotypes in isogenic human iPSC-derived cardiac tissues. | Maurissen TL et al. | β | 2024 | β |
| Navigating the Genetic Landscape: A Comprehensive Review of Novel Therapeutic Strategies for Retinitis Pigmentosa Management. | Pawar YB et al. | β | 2024 | β |
| [Neuronal models based on olfactory epithelial cells in the study of the pathogenesis of mental disorders]. | Kurishev AO et al. | β | 2024 | β |
| Novel Therapeutic Agents for Management of Diabetes Mellitus: A Hope for Drug Designing against Diabetes Mellitus. | Elkhalifa AME et al. | β | 2024 | β |
| Optical redox imaging to screen synthetic hydrogels for stem cell-derived cardiomyocyte differentiation and maturation. | Desa DE et al. | β | 2024 | β |
| Overcoming the challenges of scalable iPSC generation in translation medicine. | Liu DH et al. | β | 2024 | β |
| Phase-amplitude coupling detection and analysis of human 2-dimensional neural cultures in multi-well microelectrode array in vitro. | Salimpour Y et al. | β | 2024 | β |
| Pros and Cons of Human Brain Organoids to Study Alzheimer's Disease. | Sainz A et al. | β | 2024 | β |
| Public attitudes toward the use of human induced pluripotent stem cells: insights from an Italian adult population. | Elia N et al. | β | 2024 | β |
| Reconstitution of human tissue barrier function for precision and personalized medicine. | Kim J et al. | β | 2024 | β |
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| Single Nucleotide Polymorphism-based Identification of Bacterial Artificial Chromosome-mediated Homologous Recombination. | Chung SK | β | 2024 | β |
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| Transplantation of chemically induced pluripotent stem-cell-derived islets under abdominal anterior rectus sheath in a type 1 diabetes patient. | Wang S et al. | β | 2024 | β |
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| Unlocking the potential of low-molecular-weight (Poly)phenol metabolites: Protectors at the blood-brain barrier frontier. | Marques D et al. | β | 2024 | β |
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| Unraveling the impact of ZZZ3 on the mTOR/ribosome pathway in human embryonic stem cells homeostasis. | Lo Conte M et al. | β | 2024 | β |
| Utilizing stem cell-secreted molecules as a versatile toolbox for skin regenerative medicine. | Zheng J et al. | β | 2024 | β |
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| Activated <i>KRAS</i> reprograms neural progenitor cells to glioma stem cellβlike phenotype. | Qin Z et al. | β | 2023 | β |
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| An Insight into the Prospects and Drawbacks of Stem Cell Therapy for Spinal Cord Injuries: Ongoing Trials and Future Directions. | Khan SI et al. | β | 2023 | β |
| An Optogenetic-Controlled Cell Reprogramming System for Driving Cell Fate and Light-Responsive Chimeric Mice. | Wang M et al. | β | 2023 | β |
| Application of patient-derived induced pluripotent stem cells and organoids in inherited retinal diseases. | Liang Y et al. | β | 2023 | β |
| Application-Oriented Bulk Cryopreservation of Human iPSCs in Cryo Bags Followed by Direct Inoculation in Scalable Suspension Bioreactors for Expansion and Neural Differentiation. | Meiser I et al. | β | 2023 | β |
| A Protocol for Culture and Characterization of Human Induced Pluripotent Stem Cells After Induction. | Cheng YS et al. | β | 2023 | β |
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| Astrocytic response mediated by the CLU risk allele inhibits OPC proliferation and myelination in a human iPSC model. | Liu Z et al. | β | 2023 | β |
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| Bioengineered tissue and cell therapy products are efficiently cryopreserved with pathogen-inactivated human platelet lysate-based solutions. | MartΓn-LΓ³pez M et al. | β | 2023 | β |
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| Complexity-to-Diversity and Pseudo-Natural Product Strategies as Powerful Platforms for Deciphering Next-Generation Therapeutics. | Alkubaisi BO et al. | β | 2023 | β |
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| Context matters: hPSC-derived microglia thrive in a humanized brain environment inΒ vivo. | Cerneckis J et al. | β | 2023 | β |
| Corneal Endothelial-like Cells Derived from Induced Pluripotent Stem Cells for Cell Therapy. | Ng XY et al. | β | 2023 | β |
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| Current advances in primate genomics: novel approaches for understanding evolution and disease. | Juan D et al. | β | 2023 | β |
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| Current Status and Future Perspectives on Stem Cell-Based Therapies for Parkinson's Disease. | Cha Y et al. | β | 2023 | β |
| Developing a human iPSC-derived three-dimensional myelin spheroid platform for modeling myelin diseases. | Feng L et al. | β | 2023 | β |
| Developing Hypoimmunogenic Human iPSC-Derived Oligodendrocyte Progenitor Cells as an Off-The-Shelf Cell Therapy for Myelin Disorders. | Feng L et al. | β | 2023 | β |
| Differentiation of Hepatic Stellate Cells from Pluripotent Stem Cells. | de la Torre RAMG et al. | β | 2023 | β |
| Direct chemical induction of hepatocyte-like cells with capacity for liver repopulation. | Bai Y et al. | β | 2023 | β |
| Direct Differentiation of Bone Marrow Mononucleated Cells Into Insulin-Producing Cells Using 4 Specific Soluble Factors. | Lee SA et al. | β | 2023 | β |
| Direct Reprogramming of Mouse Fibroblasts to Osteoblast-like Cells Using Runx2/Dlx5 Factors on Engineered Stiff Hydrogels. | Zhang J et al. | β | 2023 | β |
| Efficient and safe single-cell cloning of human pluripotent stem cells using the CEPT cocktail. | Tristan CA et al. | β | 2023 | β |
| Engineered Vasculature for Cancer Research and Regenerative Medicine. | Nguyen HT et al. | β | 2023 | β |
| Engineering Extracellular Vesicles as Delivery Systems in Therapeutic Applications. | Wang L et al. | β | 2023 | β |
| Epigenetics in cardiovascular health and disease. | Chew NWS et al. | β | 2023 | β |
| Excitatory Neurons Derived from Human-Induced Pluripotent Stem Cells Show Transcriptomic Differences in Alzheimer's Patients from Controls. | Sagar R et al. | β | 2023 | β |
| Exploring potential impacts of pregnancy-related maternal immune activation and extracellular vesicles on immune alterations observed in autism spectrum disorder. | Kaminski VL et al. | β | 2023 | β |
| Exploring the promising potential of induced pluripotent stem cells in cancer research and therapy. | Chehelgerdi M et al. | β | 2023 | β |
| Extracellular matrix cues regulate the differentiation of pluripotent stem cell-derived endothelial cells. | Noh KM et al. | β | 2023 | β |
| Extracellular vesicles throughout development: A potential roadmap for emerging glioblastoma therapies. | Fernandes CFL et al. | β | 2023 | β |
| Fabricating 3-dimensional human brown adipose microtissues for transplantation studies. | Wang O et al. | β | 2023 | β |
| Functional genomics in stroke: current and future applications of iPSCs and gene editing to dissect the function of risk variants. | Granata A | β | 2023 | β |
| Future prospects in the tissue engineering of heart valves: a focus on the role of stem cells. | Albert BJ et al. | β | 2023 | β |
| Gene editing with 'pencil' rather than 'scissors' in human pluripotent stem cells. | Park JC et al. | β | 2023 | β |
| Gene Modulation with CRISPR-based Tools in Human iPSC-Cardiomyocytes. | Han JL et al. | β | 2023 | β |
| Generation of an Open-Access Patient-Derived iPSC Biobank for Amyotrophic Lateral Sclerosis Disease Modelling. | Hedges EC et al. | β | 2023 | β |
| Genome-engineering technologies for modeling and treatment of cystic fibrosis. | DΔbczyΕski M et al. | β | 2023 | β |
| Harnessing the Therapeutic Potential of Stem Cells in the Management of Chronic Obstructive Pulmonary Disease: A Comprehensive Review. | Singh PV et al. | β | 2023 | β |
| High-throughput optical sensing of peri-cellular oxygen in cardiac cells: system characterization, calibration, and testing. | Li W et al. | β | 2023 | β |
| HLA-Homozygous iPSC-Derived Mesenchymal Stem Cells Rescue Rotenone-Induced Experimental Leber's Hereditary Optic Neuropathy-like Models In Vitro and In Vivo. | Tsai ET et al. | β | 2023 | β |
| Human Brain Organoids in Migraine Research: Pathogenesis and Drug Development. | Gazerani P | β | 2023 | β |
| Human Induced Pluripotent Spheroids' Growth Is Driven by Viscoelastic Properties and Macrostructure of 3D Hydrogel Environment. | LemariΓ© L et al. | β | 2023 | β |
| Human iPSC-derived glia models for the study of neuroinflammation. | StΓΆberl N et al. | β | 2023 | β |
| Human iPSCs as Model Systems for BMP-Related Rare Diseases. | SΓ‘nchez-Duffhues G et al. | β | 2023 | β |
| Human-specific genetics: new tools to explore the molecular and cellular basis of human evolution. | Pollen AA et al. | β | 2023 | β |
| Importance of Spatial Arrangement of Cardiomyocyte Network for Precise and Stable On-Chip Predictive Cardiotoxicity Measurement. | Sakamoto K et al. | β | 2023 | β |
| Improved Method for Dental Pulp Stem Cell Preservation and Its Underlying Cell Biological Mechanism. | Takeshita-Umehara M et al. | β | 2023 | β |
| Induced pluripotent stem cell-based therapies for organ fibrosis. | Cheng W et al. | β | 2023 | β |
| Induced pluripotent stem cells: ex vivo models for human diseases due to mitochondrial DNA mutations. | Chen C et al. | β | 2023 | β |
| Intracellular delivery of therapeutic proteins. New advancements and future directions. | Porello I et al. | β | 2023 | β |
| Investigating nanoplastics toxicity using advanced stem cell-based intestinal and lung <i>in vitro</i> models. | Busch M et al. | β | 2023 | β |
| Investigation of immune-related diseases using patient-derived induced pluripotent stem cells. | Shoda H et al. | β | 2023 | β |
| In Vitro Tumor Models on Chip and Integrated Microphysiological Analysis Platform (MAP) for Life Sciences and High-Throughput Drug Screening. | Ngo H et al. | β | 2023 | β |
| iPSC-Derived Glioblastoma Cells Have Enhanced Stemness Wnt/Ξ²-Catenin Activity Which Is Negatively Regulated by Wnt Antagonist sFRP4. | Yasmin IA et al. | β | 2023 | β |
| iPSC-Derived Neurons from Patients with POLG Mutations Exhibit Decreased Mitochondrial Content and Dendrite Simplification. | Verma M et al. | β | 2023 | β |
| iPSC-derived retinal pigmented epithelial cells from patients with macular telangiectasia show decreased mitochondrial function. | Eade KT et al. | β | 2023 | β |
| [iPS cell technologies toward overcoming neurological diseases]. | Kimura T et al. | β | 2023 | β |
| Label-free and non-destructive identification of naΓ―ve and primed embryonic stem cells based on differences in cellular metabolism. | Koo KM et al. | β | 2023 | β |
| Label-free optical imaging and sensing for quality control of stem cell manufacturing. | Desa DE et al. | β | 2023 | β |
| Live birth of chimeric monkey with high contribution from embryonic stem cells. | Cao J et al. | β | 2023 | β |
| Merits and challenges of iPSC-derived organoids for clinical applications. | Xu Z et al. | β | 2023 | β |
| Mesenchymal stromal cells for bone trauma, defects, and disease: Considerations for manufacturing, clinical translation, and effective treatments. | Bowles-Welch AC et al. | β | 2023 | β |
| Micro and nanotechnologies: The little formulations that could. | Stiepel RT et al. | β | 2023 | β |
| Microscale tissue engineering of liver lobule models: advancements and applications. | Wang Q et al. | β | 2023 | β |
| Miniature-swine iPSC-derived GABA progenitor cells function in a rat Parkinson's disease model. | Guo Y et al. | β | 2023 | β |
| Modeling brain macrophage biology and neurodegenerative diseases using human iPSC-derived neuroimmune organoids. | Cerneckis J et al. | β | 2023 | β |
| Modeling mitochondrial DNA diseases: from base editing to pluripotent stem-cell-derived organoids. | Tolle I et al. | β | 2023 | β |
| Modeling RET-Rearranged Non-Small Cell Lung Cancer (NSCLC): Generation of Lung Progenitor Cells (LPCs) from Patient-Derived Induced Pluripotent Stem Cells (iPSCs). | Marcoux P et al. | β | 2023 | β |
| Molecular and Functional Characterization of Different BrainSphere Models for Use in Neurotoxicity Testing on Microelectrode Arrays. | Hartmann J et al. | β | 2023 | β |
| Myelin organoids for the study of Alzheimer's disease. | Cerneckis J et al. | β | 2023 | β |
| NANOG Dominates Interleukin-6-Induced Sphere Formation in Prostate Cancer. | Seven D et al. | β | 2023 | β |
| Nanomedicines to treat rare neurological disorders: The case of Krabbe disease. | Moore TL et al. | β | 2023 | β |
| Neuroprotective Potential of L-Glutamate Transporters in Human Induced Pluripotent Stem Cell-Derived Neural Cells against Excitotoxicity. | Takahashi K et al. | β | 2023 | β |
| New tools can propel research in lysosomal storage diseases. | Hertz E et al. | β | 2023 | β |
| On-chip real-time impedance monitoring of hiPSC-derived and artificial basement membrane-supported endothelium. | Huang X et al. | β | 2023 | β |
| On the utilization of the induced pluripotent stem cell (iPSC) model to study substance use disorders: A scoping review protocol. | Niemis W et al. | β | 2023 | β |
| Oogenesis in Women: From Molecular Regulatory Pathways and Maternal Age to Stem Cells. | Krajnik K et al. | β | 2023 | β |
| Organoid cultures for cancer modeling. | Yan HHN et al. | β | 2023 | β |
| Overexpression of KCNJ2 enhances maturation of human-induced pluripotent stem cell-derived cardiomyocytes. | Zhou J et al. | β | 2023 | β |
| Patient-derived organoids for precision oncology: a platform to facilitate clinical decision making. | Chitrangi S et al. | β | 2023 | β |
| Patient-specific iPSC-derived cardiomyocytes reveal variable phenotypic severity of Brugada syndrome. | Sun Y et al. | β | 2023 | β |
| Pluripotent stem cell-derived neural progenitor cells can be used to model effects of IL-6 on human neurodevelopment. | Sarieva K et al. | β | 2023 | β |
| Production of Highly Uniform Midbrain Organoids from Human Pluripotent Stem Cells. | Yao X et al. | β | 2023 | β |
| Progress and Prospects of Gene Editing in Pluripotent Stem Cells. | Zhang Z et al. | β | 2023 | β |
| Proteomics and disease network associations evaluation of environmentally relevant Bisphenol A concentrations in a human 3D neural stem cell model. | HorΓ‘nszky A et al. | β | 2023 | β |
| Pushing the boundaries of brain organoids to study Alzheimer's disease. | Cerneckis J et al. | β | 2023 | β |
| Recognizing the Differentiation Degree of Human Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium Cells Using Machine Learning and Deep Learning-Based Approaches. | Lien CY et al. | β | 2023 | β |
| Reprogramming of Acute Myeloid Leukemia Patients Cells: Harboring Cancer Mutations Requires Targeting of AML Hierarchy. | Golubeva D et al. | β | 2023 | β |
| Revolutionizing Disease Modeling: The Emergence of Organoids in Cellular Systems. | Silva-Pedrosa R et al. | β | 2023 | β |
| Role of curcumin and its nanoformulations in the treatment of neurological diseases through the effects on stem cells. | Sabouni N et al. | β | 2023 | β |
| Small Extracellular Vesicles Derived from Induced Pluripotent Stem Cells in the Treatment of Myocardial Injury. | Meng WT et al. | β | 2023 | β |
| Structurally Defined Water-Soluble Metallofullerene Derivatives towards Biomedical Applications. | Li Y et al. | β | 2023 | β |
| Targeting the redox system for cardiovascular regeneration in aging. | Allemann MS et al. | β | 2023 | β |
| Technological aspects of manufacturing and analytical control of biological nanoparticles. | Brezgin S et al. | β | 2023 | β |
| Temperature-boosted PAM-less activation of CRISPR-Cas12a combined with selective inhibitors enhances detection of SNVs with VAFs below 0.01. | Chen K et al. | β | 2023 | β |
| The Multifaceted Role of WNT Signaling in Alzheimer's Disease Onset and Age-Related Progression. | Kostes WW et al. | β | 2023 | β |
| Therapeutical growth in oligodendroglial fate induction via transdifferentiation of stem cells for neuroregenerative therapy. | Dwivedi S et al. | β | 2023 | β |
| T, NK, then macrophages: Recent advances and challenges in adaptive immunotherapy from human pluripotent stem cells. | Hang S et al. | β | 2023 | β |
| Toward the use of novel alternative methods in epilepsy modeling and drug discovery. | Miguel Sanz C et al. | β | 2023 | β |
| Transcription factors and splice factors - interconnected regulators of stem cell differentiation. | Mehlferber MM et al. | β | 2023 | β |
| Trichostatin A for Efficient CRISPR-Cas9 Gene Editing of Human Pluripotent Stem Cells. | Molugu K et al. | β | 2023 | β |
| Twenty-five years of clinical applications using adaptive optics ophthalmoscopy [Invited]. | Morgan JIW et al. | β | 2023 | β |
| Unlocking Neural Function with 3D In Vitro Models: A Technical Review of Self-Assembled, Guided, and Bioprinted Brain Organoids and Their Applications in the Study of Neurodevelopmental and Neurodegenerative Disorders. | D'Antoni C et al. | β | 2023 | β |
| Use of <i>in vitro</i> derived human neuronal models to study host-parasite interactions of <i>Toxoplasma gondii</i> in neurons and neuropathogenesis of chronic toxoplasmosis. | Halonen SK | β | 2023 | β |
| Using Biosensors to Study Organoids, Spheroids and Organs-on-a-Chip: A Mechanobiology Perspective. | Yousafzai MS et al. | β | 2023 | β |
| Using Human-Induced Pluripotent Stem Cell Derived Neurons on Microelectrode Arrays to Model Neurological Disease: A Review. | Lv S et al. | β | 2023 | β |
| Vascularized adipose tissue engineering: moving towards soft tissue reconstruction. | Peirsman A et al. | β | 2023 | β |
| What connects splicing of transfer RNA precursor molecules with pontocerebellar hypoplasia? | Sekulovski S et al. | β | 2023 | β |
| Whole-Heart Tissue Engineering and Cardiac Patches: Challenges and Promises. | Akbarzadeh A et al. | β | 2023 | β |
| Xeno-free culture and proliferation of hPSCs on 2D biomaterials. | Wang T et al. | β | 2023 | β |
| Xeno-free generation of human induced pluripotent stem cells from donor-matched fibroblasts isolated from dermal and oral tissues. | Ali HRW et al. | β | 2023 | β |
| Across Dimensions: Developing 2D and 3D Human iPSC-Based Models of Fragile X Syndrome. | Lee A et al. | β | 2022 | β |
| Advanced In Vitro Lung Models for Drug and Toxicity Screening: The Promising Role of Induced Pluripotent Stem Cells. | Moreira A et al. | β | 2022 | β |
| Advances in Cardiac Tissue Engineering. | Kitsuka T et al. | β | 2022 | β |
| Adventures and Advances in Time Travel With Induced Pluripotent Stem Cells and Automated Patch Clamp. | Rosholm KR et al. | β | 2022 | β |
| A genetically engineered, stem-cell-derived cellular vaccine. | Cooper A et al. | β | 2022 | β |
| A human stem cell resource to decipher the biochemical and cellular basis of neurodevelopmental defects in Lowe syndrome. | Akhtar BM et al. | β | 2022 | β |
| A Microfluidic In Vitro Three-Dimensional Dynamic Model of the Blood-Brain Barrier to Study the Transmigration of Immune Cells. | Meena M et al. | β | 2022 | β |
| An Alternate Approach to Generate Induced Pluripotent Stem Cells with Precise CRISPR/Cas9 Tool. | Javaid N et al. | β | 2022 | β |
| Anti-fibrotic effect of a selective estrogen receptor modulator in systemic sclerosis. | Kim Y et al. | β | 2022 | β |
| Applications of human organoids in the personalized treatment for digestive diseases. | Wang Q et al. | β | 2022 | β |
| Approaches and materials for endocytosis-independent intracellular delivery of proteins. | Chen N et al. | β | 2022 | β |
| Autologous iPSC-Derived Human Neuromuscular Junction to Model the Pathophysiology of Hereditary Spastic Paraplegia. | Costamagna D et al. | β | 2022 | β |
| Autophagy and pluripotency: self-eating your way to eternal youth. | Xu Y et al. | β | 2022 | β |
| Bio-3D printing of scaffold-free osteogenic and chondrogenic constructs using rat adipose-derived stromal cells. | Fujimoto R et al. | β | 2022 | β |
| Biomaterial application strategies to enhance stem cell-based therapy for ischemic stroke. | Mohd Satar A et al. | β | 2022 | β |
| Bioprocess Economic Modeling: Decision Support Tools for the Development of Stem Cell Therapy Products. | Salvador WOS et al. | β | 2022 | β |
| Cannabinoid receptor 1 antagonist genistein attenuates marijuana-induced vascular inflammation. | Wei TT et al. | β | 2022 | β |
| Cell Culture Process Scale-Up Challenges for Commercial-Scale Manufacturing of Allogeneic Pluripotent Stem Cell Products. | Lee B et al. | β | 2022 | β |
| Challenges and Future of Drug-Induced Liver Injury Research-Laboratory Tests. | Weber S et al. | β | 2022 | β |
| Chronic Cardiotoxicity Assays Using Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes (hiPSC-CMs). | Narkar A et al. | β | 2022 | β |
| CRISPR/Cas9-mediated gene knockout and interallelic gene conversion in human induced pluripotent stem cells using non-integrative bacteriophage-chimeric retrovirus-like particles. | MiannΓ© J et al. | β | 2022 | β |
| Cross Talk opposing view: Animal models of epilepsy are more useful than human tissue-based approaches. | Richardson A et al. | β | 2022 | β |
| Decellularized extracellular matrix scaffolds: Recent trends and emerging strategies in tissue engineering. | Zhang X et al. | β | 2022 | β |
| Decoding microRNAs in autism spectrum disorder. | Li J et al. | β | 2022 | β |
| Deep Learning-Assisted Automated Single Cell Electroporation Platform for Effective Genetic Manipulation of Hard-to-Transfect Cells. | Mukherjee P et al. | β | 2022 | β |
| Dental applications of induced pluripotent stem cells and their derivatives. | Gao P et al. | β | 2022 | β |
| Dental Pulp-Derived Stem Cells Reduce Inflammation, Accelerate Wound Healing and Mediate M2 Polarization of Myeloid Cells. | Anderson S et al. | β | 2022 | β |
| Derivation and Differentiation of Human Pluripotent Stem Cells in Microfluidic Devices. | Luni C et al. | β | 2022 | β |
| Developing CRISPR/Cas9-Mediated Fluorescent Reporter Human Pluripotent Stem-Cell Lines for High-Content Screening. | Vojnits K et al. | β | 2022 | β |
| Development of a 48-Well Dynamic Suspension Culture System for Pancreatic Differentiation from Human Embryonic Stem Cells. | Song Y et al. | β | 2022 | β |
| Development of a Personalized Intestinal Fibrosis Model Using Human Intestinal Organoids Derived From Induced Pluripotent Stem Cells. | Estrada HQ et al. | β | 2022 | β |
| Direct Reprograming of Mouse Fibroblasts into Dermal Papilla Cells via Small Molecules. | Ma Y et al. | β | 2022 | β |
| Distinctive Clinical and Pathologic Features of Immature Teratomas Arising from Induced Pluripotent Stem Cell-Derived Beta Cell Injection in a Diabetes Patient. | Han L et al. | β | 2022 | β |
| Druggable transcriptomic pathways revealed in Parkinson's patient-derived midbrain neurons. | van den Hurk M et al. | β | 2022 | β |
| Ectopic Expression of FVIII in HPCs and MSCs Derived from hiPSCs with Site-Specific Integration of <i>ITGA2B</i> Promoter-Driven <i>BDDF8</i> Gene in Hemophilia A. | Zhao J et al. | β | 2022 | β |
| Electrophysiological Properties of Induced Pluripotent Stem Cell-Derived Midbrain Dopaminergic Neurons Correlate With Expression of Tyrosine Hydroxylase. | Rakovic A et al. | β | 2022 | β |
| Engineered Tissue for Cardiac Regeneration: Current Status and Future Perspectives. | Li J et al. | β | 2022 | β |
| Engineering a living cardiac pump on a chip using high-precision fabrication. | Michas C et al. | β | 2022 | β |
| Engineering complexity in human tissue models of cancer. | Ronaldson-Bouchard K et al. | β | 2022 | β |
| Engineering Induced Pluripotent Stem Cells for Cancer Immunotherapy. | Zhou Y et al. | β | 2022 | β |
| Enhancing iPSC-CM Maturation Using a Matrigel-Coated Micropatterned PDMS Substrate. | Jimenez-Vazquez EN et al. | β | 2022 | β |
| Epithelial-derived factors induce muscularis mucosa of human induced pluripotent stem cell-derived gastric organoids. | Uehara K et al. | β | 2022 | β |
| Establishment and Characterization of MUi027-A: A Novel Patient-Derived Cell Line of Polycystic Kidney Disease with <i>PKD1</i> Mutation. | Linn AK et al. | β | 2022 | β |
| Evaluation of immunosuppression protocols for MHC-matched allogeneic iPS cell-based transplantation using a mouse skin transplantation model. | Kamatani T et al. | β | 2022 | β |
| Expanding the Differentiation Potential of Already-Established Pluripotent Stem Cells. | GonzΓ‘lez-MartΓnez J et al. | β | 2022 | β |
| Exploring the Potential of Symmetric Exon Deletion to Treat Non-Ischemic Dilated Cardiomyopathy by Removing Frameshift Mutations in <i>TTN</i>. | Rodriguez-Polo I et al. | β | 2022 | β |
| Fabrication of Polymer/Graphene Biocomposites for Tissue Engineering. | Meneses J et al. | β | 2022 | β |
| Focus on organoids: cooperation and interconnection with extracellular vesicles - Is this the future of in vitro modeling? | Jurj A et al. | β | 2022 | β |
| Gene editing of human iPSCs rescues thrombophilia in hereditary antithrombin deficiency in mice. | Tang LV et al. | β | 2022 | β |
| Generating pancreatic beta-like cells from human pluripotent stem cells. | Lim LY et al. | β | 2022 | β |
| Generation and characterization of motor neuron progenitors and motor neurons using metachromatic leukodystrophy-induced pluripotent stem cells. | Hossain MA et al. | β | 2022 | β |
| Generation and Differentiation of Induced Pluripotent Stem Cells from Mononuclear Cells in An Age-Related Macular Degeneration Patient. | Wang T et al. | β | 2022 | β |
| Generation of Human Induced Pluripotent Stem Cells from Renal Epithelial Cells. | Yu M et al. | β | 2022 | β |
| Generation of Human Induced Pluripotent Stem Cells Using Endothelial Progenitor Cells Derived from Umbilical Cord Blood and Adult Peripheral Blood. | Gao X et al. | β | 2022 | β |
| Generation of Induced Pluripotent Stem Cells from Human Bone Marrow-Derived Mesenchymal Stem Cells. | Koyuncu Irmak D et al. | β | 2022 | β |
| Generation of Quiescent Cardiac Fibroblasts Derived from Human Induced Pluripotent Stem Cells. | Zhang H et al. | β | 2022 | β |
| Genetic enhancement: an avenue to combat aging-related diseases. | Cai Y et al. | β | 2022 | β |
| Global trends and hot topics in electrical stimulation of skeletal muscle research over the past decade: A bibliometric analysis. | Huang Y et al. | β | 2022 | β |
| Hair Follicle Stem Cells for Tissue Regeneration. | Peterson A et al. | β | 2022 | β |
| Hematopoietic differentiation persists in human iPSCs defective in de novo DNA methylation. | Cypris O et al. | β | 2022 | β |
| Here and there a trophoblast, a transcriptional evaluation of trophoblast cell models. | Cox BJ et al. | β | 2022 | β |
| High-throughput "read-on-ski" automated imaging and label-free detection system for toxicity screening of compounds using personalised human kidney organoids. | Wang Q et al. | β | 2022 | β |
| Histone modifications in neurodifferentiation of embryonic stem cells. | Huang M et al. | β | 2022 | β |
| Human airway lineages derived from pluripotent stem cells reveal the epithelial responses to SARS-CoV-2 infection. | Wang R et al. | β | 2022 | β |
| Human-Based New Approach Methodologies in Developmental Toxicity Testing: A Step Ahead from the State of the Art with a Feto-Placental Organ-on-Chip Platform. | Luconi M et al. | β | 2022 | β |
| Human Induced Pluripotent Stem Cell (iPSC) Handling Protocols: Maintenance, Expansion, and Cryopreservation. | Marotta D et al. | β | 2022 | β |
| Human Induced Pluripotent Stem Cell Phenotyping and Preclinical Modeling of Familial Parkinson's Disease. | Kim J et al. | β | 2022 | β |
| Human In Vitro Models of Epilepsy Using Embryonic and Induced Pluripotent Stem Cells. | Javaid MS et al. | β | 2022 | β |
| Human in vitro neurocardiac coculture (ivNCC) assay development for evaluating cardiac contractility modulation. | Narkar A et al. | β | 2022 | β |
| Human iPSC-Cardiomyocytes as an Experimental Model to Study Epigenetic Modifiers of Electrophysiology. | Pozo MR et al. | β | 2022 | β |
| Human mini-blood-brain barrier models for biomedical neuroscience research: a review. | Tran M et al. | β | 2022 | β |
| Human Pluripotent Stem Cell Differentiation to Microglia. | Ijaz L et al. | β | 2022 | β |
| Human Pluripotent Stem Cells for High-Throughput Drug Screening and Characterization of Small Molecules. | Ryu S et al. | β | 2022 | β |
| Imprinting fidelity in mouse iPSCs depends on sex of donor cell and medium formulation. | Arez M et al. | β | 2022 | β |
| Improving three-dimensional human pluripotent cell culture efficiency via surface molecule coating. | Li Q et al. | β | 2022 | β |
| Induced pluripotent stem cell-based disease modeling and prospective immune therapy for coronavirus disease 2019. | Chakrabarty K et al. | β | 2022 | β |
| Induced Pluripotent Stem Cells for Inherited Optic Neuropathies-Disease Modeling and Therapeutic Development. | Harvey JP et al. | β | 2022 | β |
| Induced pluripotent stem cells: Generation methods and a new perspective in COVID-19 research. | Karami Z et al. | β | 2022 | β |
| Inherited retinal diseases: Linking genes, disease-causing variants, and relevant therapeutic modalities. | Schneider N et al. | β | 2022 | β |
| Insights into Human-Induced Pluripotent Stem Cell-Derived Astrocytes in Neurodegenerative Disorders. | Kumar M et al. | β | 2022 | β |
| Insights into the Genetic Profile of Two Siblings Affected by Unverricht-Lundborg Disease Using Patient-Derived hiPSCs. | Lucchino V et al. | β | 2022 | β |
| Investigating Cutaneous Squamous Cell Carcinoma <i>in vitro</i> and <i>in vivo</i>: Novel 3D Tools and Animal Models. | Quadri M et al. | β | 2022 | β |
| In Vitro Differentiation of Human Amniotic Epithelial Cells into Hepatocyte-like Cells. | Michalik M et al. | β | 2022 | β |
| LMCD1 facilitates the induction of pluripotency via cell proliferation, metabolism, and epithelial-mesenchymal transition. | Ye Z et al. | β | 2022 | β |
| Long noncoding RNAs in induced pluripotent stem cells and their differentiation. | Ilieva M et al. | β | 2022 | β |
| Long-term morphological and functional dynamics of human stem cell-derived neuronal networks on high-density micro-electrode arrays. | Habibey R et al. | β | 2022 | β |
| Lupus Heart Disease Modeling with Combination of Induced Pluripotent Stem Cell-Derived Cardiomyocytes and Lupus Patient Serum. | Park N et al. | β | 2022 | β |
| Mesenchymal stem cell-derived extracellular vesicles for cell-free therapy of ocular diseases. | Liu X et al. | β | 2022 | β |
| Mesenchymal Stromal Cells in Ischemic Brain Injury. | Brooks B et al. | β | 2022 | β |
| Microphysiological Neurovascular Barriers to Model the Inner Retinal Microvasculature. | Maurissen TL et al. | β | 2022 | β |
| MicroRNA Roles in Cell Reprogramming Mechanisms. | Pascale E et al. | β | 2022 | β |
| Migratory and anti-fibrotic programmes define the regenerative potential of human cardiac progenitors. | Poch CM et al. | β | 2022 | β |
| Mitochondrial HSF1 triggers mitochondrial dysfunction and neurodegeneration in Huntington's disease. | Liu C et al. | β | 2022 | β |
| Modeling Central Nervous System Injury In Vitro: Current Status and Promising Future Strategies. | PilipoviΔ K et al. | β | 2022 | β |
| Modeling Movement Disorders via Generation of hiPSC-Derived Motor Neurons. | Akter M et al. | β | 2022 | β |
| Natural recovery and regeneration of the central nervous system. | Verma N et al. | β | 2022 | β |
| Navigating ethical challenges in the development and translation of biomaterials research. | Hunckler MD et al. | β | 2022 | β |
| Neural progenitor cell-derived extracellular matrix as a new platform for neural differentiation of human induced pluripotent stem cells. | Carvalho MS et al. | β | 2022 | β |
| Neuronal hyperexcitability and ion channel dysfunction in CDKL5-deficiency patient iPSC-derived cortical organoids. | Wu W et al. | β | 2022 | β |
| Non-human primate pluripotent stem cells for the preclinical testing of regenerative therapies. | Rodriguez-Polo I et al. | β | 2022 | β |
| Nucleus reprogramming/remodeling through selective enucleation (SE) of immature oocytes and zygotes: a nucleolus point of view. | Fulka H et al. | β | 2022 | β |
| Off-the-Shelf Chimeric Antigen Receptor Immune Cells from Human Pluripotent Stem Cells. | Cao H et al. | β | 2022 | β |
| Organoids in gastrointestinal diseases: from experimental models to clinical translation. | GΓΌnther C et al. | β | 2022 | β |
| Organ-On-A-Chip Models of the Blood-Brain Barrier: Recent Advances and Future Prospects. | Kawakita S et al. | β | 2022 | β |
| Oxygen control: the often overlooked but essential piece to create better <i>in vitro</i> systems. | Palacio-CastaΓ±eda V et al. | β | 2022 | β |
| Patient-derived organoids for therapy personalization in inflammatory bowel diseases. | LucafΓ² M et al. | β | 2022 | β |
| Personalized Scaffolds for Diabetic Foot Ulcer Healing Using Extracellular Matrix from Induced Pluripotent Stem-Reprogrammed Patient Cells. | Santarella F et al. | β | 2022 | β |
| Perspectives on Bulk-Tissue RNA Sequencing and Single-Cell RNA Sequencing for Cardiac Transcriptomics. | Hegenbarth JC et al. | β | 2022 | β |
| Perspectives on Mechanisms Supporting Neuronal Polarity From Small Animals to Humans. | Wilson C et al. | β | 2022 | β |
| Phenotypical, functional and transcriptomic comparison of two modified methods of hepatocyte differentiation from human induced pluripotent stem cells. | Li R et al. | β | 2022 | β |
| Photothermal scaffolds/surfaces for regulation of cell behaviors. | Qu Y et al. | β | 2022 | β |
| Rapid and Highly Efficient Isolation and Purification of Human Induced Pluripotent Stem Cells. | Gao X et al. | β | 2022 | β |
| Recent advances of biomaterials in stem cell therapies. | Xue Y et al. | β | 2022 | β |
| Regenerative Neurology and Regenerative Cardiology: Shared Hurdles and Achievements. | MitreΔiΔ D et al. | β | 2022 | β |
| Retroviral infection of human neurospheres and use of stem Cell EVs to repair cellular damage. | Branscome H et al. | β | 2022 | β |
| Role of Chaperone-Mediated Autophagy in Ageing Biology and Rejuvenation of Stem Cells. | Vitale E et al. | β | 2022 | β |
| Single-cell mass cytometry analysis reveals stem cell heterogeneity. | Meharwade T et al. | β | 2022 | β |
| Single-cell transcriptomic profiling reveals specific maturation signatures in human cardiomyocytes derived from <i>LMNB2</i>-inactivated induced pluripotent stem cells. | Wang J et al. | β | 2022 | β |
| Spinal motor neuron transplantation to enhance nerve reconstruction strategies: Towards a cell therapy. | Bazarek S et al. | β | 2022 | β |
| Statistically derived geometrical landscapes capture principles of decision-making dynamics during cell fate transitions. | SΓ‘ez M et al. | β | 2022 | β |
| Stem Cell Based Approaches to Modulate the Matrix Milieu in Vascular Disorders. | S S et al. | β | 2022 | β |
| Stem cells for organoids. | Qian S et al. | β | 2022 | β |
| Stem Cell Therapies for Chronic Liver Diseases: Progress and Challenges. | Li TT et al. | β | 2022 | β |
| Stem cell therapy in liver regeneration: Focus on mesenchymal stem cells and induced pluripotent stem cells. | Zhang L et al. | β | 2022 | β |
| Structural Variation at a Disease Mutation Hotspot: Strategies to Investigate Gene Regulation and the 3D Genome. | Boyling A et al. | β | 2022 | β |
| Substantial somatic genomic variation and selection for BCOR mutations in human induced pluripotent stem cells. | Rouhani FJ et al. | β | 2022 | β |
| Super-enhancers conserved within placental mammals maintain stem cell pluripotency. | Zhang J et al. | β | 2022 | β |
| Systemic proteomics and miRNA profile analysis of exosomes derived from human pluripotent stem cells. | Bi Y et al. | β | 2022 | β |
| Targeting NMDA receptors in neuropsychiatric disorders by drug screening on human neurons derived from pluripotent stem cells. | Zhang W et al. | β | 2022 | β |
| The Development of Tissue Engineering Scaffolds Using Matrix from iPS-Reprogrammed Fibroblasts. | Santarella F et al. | β | 2022 | β |
| The Pivotal Role of Chemical Modifications in mRNA Therapeutics. | Liu A et al. | β | 2022 | β |
| The Progress of Stem Cell Therapy in Myocardial-Infarcted Heart Regeneration: Cell Sheet Technology. | Munderere R et al. | β | 2022 | β |
| Therapeutic development for Canavan disease using patient iPSCs introduced with the wild-type <i>ASPA</i> gene. | Chao J et al. | β | 2022 | β |
| The Role of Bone Morphogenetic Protein Receptor Type 2 (<i>BMPR2</i>) and the Prospects of Utilizing Induced Pluripotent Stem Cells (iPSCs) in Pulmonary Arterial Hypertension Disease Modeling. | Devendran A et al. | β | 2022 | β |
| The role of metabolism in directed differentiation versus trans-differentiation of cardiomyocytes. | Jahng JWS et al. | β | 2022 | β |
| The universal stem cell. | Quesenberry PJ et al. | β | 2022 | β |
| The use of fibroblasts as a valuable strategy for studying mitochondrial impairment in neurological disorders. | Olesen MA et al. | β | 2022 | β |
| The use of new CRISPR tools in cardiovascular research and medicine. | Nishiga M et al. | β | 2022 | β |
| Three-Dimensional Vessels-on-a-Chip Based on hiPSC-derived Vascular Endothelial and Smooth Muscle Cells. | Bulut M et al. | β | 2022 | β |
| Thyroid hormones regulate cardiac repolarization and QT-interval related gene expression in hiPSC cardiomyocytes. | Ulivieri A et al. | β | 2022 | β |
| Tissue Engineering as a Promising Treatment for Glottic Insufficiency: A Review on Biomolecules and Cell-Laden Hydrogel. | Ng WC et al. | β | 2022 | β |
| Topologically controlled circuits of human iPSC-derived neurons for electrophysiology recordings. | Girardin S et al. | β | 2022 | β |
| Toward in Vitro Production of Platelet from Induced Pluripotent Stem Cells. | Izady E et al. | β | 2022 | β |
| Tracking connectivity maps in human stem cell-derived neuronal networks by holographic optogenetics. | Schmieder F et al. | β | 2022 | β |
| Transcriptional comparison of adult human primary Retinal Pigment Epithelium, human pluripotent stem cell-derived Retinal Pigment Epithelium, and ARPE19 cells. | Markert EK et al. | β | 2022 | β |
| Transcriptome and proteome profiling of activated cardiac fibroblasts supports target prioritization in cardiac fibrosis. | Moita MR et al. | β | 2022 | β |
| Translational potential of hiPSCs in predictive modeling of heart development and disease. | Mansfield C et al. | β | 2022 | β |
| Transplantation of fat tissues and iPSC-derived energy expenditure adipocytes to counteract obesity-driven metabolic disorders: Current strategies and future perspectives. | Dani V et al. | β | 2022 | β |
| Transplantation of Human Induced Pluripotent Stem Cell-Derived Airway Cells on Vitrigel Membrane into Rat Nasal Cavity. | Kuwata F et al. | β | 2022 | β |
| Treating Duchenne Muscular Dystrophy: The Promise of Stem Cells, Artificial Intelligence, and Multi-Omics. | Vera CD et al. | β | 2022 | β |
| Treatment of Pelvic Organ Prolapse by the Downregulation of the Expression of Mitofusin 2 in Uterosacral Ligament Tissue via Mesenchymal Stem Cells. | Wang X et al. | β | 2022 | β |
| Universal Markers for hiPSCs Residue Detection. | Shi H et al. | β | 2022 | β |
| Using MS induced pluripotent stem cells to investigate MS aetiology. | Fortune AJ et al. | β | 2022 | β |
| Addressing Manufacturing Challenges for Commercialization of iPSC-Based Therapies. | Dashtban M et al. | β | 2021 | β |
| Advanced Bio-Based Polymers for Astrocyte Cell Models. | GradiΕ‘nik L et al. | β | 2021 | β |
| Advanced preclinical models for evaluation of drug-induced liver injury - consensus statement by the European Drug-Induced Liver Injury Network [PRO-EURO-DILI-NET]. | Fernandez-Checa JC et al. | β | 2021 | β |
| Advances in Regeneration of Retinal Ganglion Cells and Optic Nerves. | Yuan F et al. | β | 2021 | β |
| Advantages and challenges of stem cell therapy for osteoarthritis (Review). | Loo SJQ et al. | β | 2021 | β |
| AI-based language models powering drug discovery and development. | Liu Z et al. | β | 2021 | β |
| A monolayer hiPSC culture system for autophagy/mitophagy studies in human dopaminergic neurons. | Stathakos P et al. | β | 2021 | β |
| An Alternative Cell Therapy for Cancers: Induced Pluripotent Stem Cell (iPSC)-Derived Natural Killer Cells. | Hsu LJ et al. | β | 2021 | β |
| An ERK5-KLF2 signalling module regulates early embryonic gene expression and telomere rejuvenation in stem cells. | Brown HA et al. | β | 2021 | β |
| A neuropathological cell model derived from Niemann-Pick disease type C patient-specific iPSCs shows disruption of the p62/SQSTM1-KEAP1-NRF2 Axis and impaired formation of neuronal networks. | Saito R et al. | β | 2021 | β |
| Angiogenesis in Regenerative Dentistry: Are We Far Enough for Therapy? | Baru O et al. | β | 2021 | β |
| A Novel Isogenic Human Cell-Based System for MEN1 Syndrome Generated by CRISPR/Cas9 Genome Editing. | Klementieva N et al. | β | 2021 | β |
| ApoE-Isoform-Dependent SARS-CoV-2 Neurotropism and Cellular Response. | Wang C et al. | β | 2021 | β |
| Application of regenerative medicine to salivary gland hypofunction. | Tanaka J et al. | β | 2021 | β |
| Application of the Pluripotent Stem Cells and Genomics in Cardiovascular Research-What We Have Learnt and Not Learnt until Now. | Simeon M et al. | β | 2021 | β |
| Approaches to characterize the transcriptional trajectory of human myogenesis. | Lim H et al. | β | 2021 | β |
| Atrial Fibrillation in Inherited Channelopathies. | Al-Azaam B et al. | β | 2021 | β |
| Automating Human Induced Pluripotent Stem Cell Culture and Differentiation of iPSC-Derived Retinal Pigment Epithelium for Personalized Drug Testing. | Truong V et al. | β | 2021 | β |
| A versatile polypharmacology platform promotes cytoprotection and viability of human pluripotent and differentiated cells. | Chen Y et al. | β | 2021 | β |
| Bioabsorbable nerve conduits three-dimensionally coated with human induced pluripotent stem cell-derived neural stem/progenitor cells promote peripheral nerve regeneration in rats. | Onode E et al. | β | 2021 | β |
| Bioinspired 3D Culture in Nanoliter Hyaluronic Acid-Rich Core-Shell Hydrogel Microcapsules Isolates Highly Pluripotent Human iPSCs. | Xu J et al. | β | 2021 | β |
| Biological implications of genetic variations in autism spectrum disorders from genomics studies. | Zhang Y et al. | β | 2021 | β |
| Cardiac optogenetics: a decade of enlightenment. | Entcheva E et al. | β | 2021 | β |
| Cardiotoxicity of Antineoplastic Therapies and Applications of Induced Pluripotent Stem Cell-Derived Cardiomyocytes. | Huang MF et al. | β | 2021 | β |
| Cell Models and Omics Techniques for the Study of Nonalcoholic Fatty Liver Disease: Focusing on Stem Cell-Derived Cell Models. | PelechΓ‘ M et al. | β | 2021 | β |
| Cell Reprogramming to Model Huntington's Disease: A Comprehensive Review. | Monk R et al. | β | 2021 | β |
| Comparative assessment of toxic responses in 3D embryoid body differentiation model and mouse early embryos treated with 5-hydroxytryptophan. | Gordeeva O et al. | β | 2021 | β |
| Comparison of Developmental Dynamics in Human Fetal Retina and Human Pluripotent Stem Cell-Derived Retinal Tissue. | Singh RK et al. | β | 2021 | β |
| Content and Method of Information for Participants in Clinical Studies With Induced Pluripotent Stem Cells (iPSCs). | Orzechowski M et al. | β | 2021 | β |
| CRISPR-Cas Gene Perturbation and Editing in Human Induced Pluripotent Stem Cells. | van Essen M et al. | β | 2021 | β |
| CRISPRi/a Screening with Human iPSCs. | Nishiga M et al. | β | 2021 | β |
| Cytoskeletal prestress: The cellular hallmark in mechanobiology and mechanomedicine. | Chowdhury F et al. | β | 2021 | β |
| Deficiency in MT5-MMP Supports Branching of Human iPSCs-Derived Neurons and Reduces Expression of GLAST/S100 in iPSCs-Derived Astrocytes. | Arnst N et al. | β | 2021 | β |
| Detection and Functional Evaluation of the P2X7 Receptor in hiPSC Derived Neurons and Microglia-Like Cells. | FrancistiovΓ‘ L et al. | β | 2021 | β |
| Developing nociceptor-selective treatments for acute and chronic pain. | Jayakar S et al. | β | 2021 | β |
| Directed Differentiation of Human Pluripotent Stem Cells toward Skeletal Myogenic Progenitors and Their Purification Using Surface Markers. | Xu N et al. | β | 2021 | β |
| Direct Reprogramming of Fibroblasts to Astrocytes Using Small Molecules. | Tian E et al. | β | 2021 | β |
| Dissecting Alzheimer's disease pathogenesis in human 2D and 3D models. | Cenini G et al. | β | 2021 | β |
| Distinct effects of V617F and exon12-mutated JAK2 expressions on erythropoiesis in a human induced pluripotent stem cell (iPSC)-based model. | Nilsri N et al. | β | 2021 | β |
| DNA Homeostasis and Senescence: Lessons from the Naked Mole Rat. | Boughey H et al. | β | 2021 | β |
| Drug Repurposing for Rare Diseases. | Roessler HI et al. | β | 2021 | β |
| DYRK1A Inhibitors as Potential Therapeutics for Ξ²-Cell Regeneration for Diabetes. | Kumar K et al. | β | 2021 | β |
| Efficient and gentle delivery of molecules into cells with different elasticity <i>via</i> Progressive Mechanoporation. | Uvizl A et al. | β | 2021 | β |
| Emerging Opportunities in Human Pluripotent Stem-Cells Based Assays to Explore the Diversity of Botulinum Neurotoxins as Future Therapeutics. | Duchesne de Lamotte J et al. | β | 2021 | β |
| Evaluation of the Therapeutic Potential of Human iPSCs in a Murine Model of VML. | Wu J et al. | β | 2021 | β |
| Exploring the Role of Skeletal Muscle in Insulin Resistance: Lessons from Cultured Cells to Animal Models. | Feraco A et al. | β | 2021 | β |
| Extracellular Recording of Entire Neural Networks Using a Dual-Mode Microelectrode Array With 19584 Electrodes and High SNR. | Yuan X et al. | β | 2021 | β |
| Fabrication approaches for high-throughput and biomimetic disease modeling. | Grubb ML et al. | β | 2021 | β |
| Gelatin MAGIC powder as nutrient-delivering 3D spacer for growing cell sheets into cost-effective cultured meat. | Park S et al. | β | 2021 | β |
| Generation of Human Induced Pluripotent Stem Cells and Differentiation into Cardiomyocytes. | Han L et al. | β | 2021 | β |
| Generation of Induced Pluripotent Stem Cells from Patients with Multiple Myeloma | YΔ±lmaz BaΕaran Δ° et al. | β | 2021 | β |
| Generation of RRMS and PPMS specific iPSCs as a platform for modeling Multiple Sclerosis. | Mutukula N et al. | β | 2021 | β |
| Generation of Skin Organoids: Potential Opportunities and Challenges. | Sun H et al. | β | 2021 | β |
| Generation of Systemic Lupus Erythematosus Patient-Derived Induced Pluripotent Stem Cells from Blood. | Li W et al. | β | 2021 | β |
| Generation of Vascular Smooth Muscle Cells From Induced Pluripotent Stem Cells: Methods, Applications, and Considerations. | Shen M et al. | β | 2021 | β |
| Genetically modified cell sheets in regenerative medicine and tissue engineering. | Jiang Z et al. | β | 2021 | β |
| Genetic influences on viral-induced cytokine responses in the lung. | Forbester JL et al. | β | 2021 | β |
| Genetic modification by overexpression of target gene in mesenchymal stromal cell for treating liver diseases. | Hu C et al. | β | 2021 | β |
| Genome editing of hPSCs: Recent progress in hPSC-based disease modeling for understanding disease mechanisms. | Choi DK et al. | β | 2021 | β |
| Harnessing the Potential of CRISPR/Cas in Atherosclerosis: Disease Modeling and Therapeutic Applications. | Siew WS et al. | β | 2021 | β |
| Hereditary Optic Neuropathies: Induced Pluripotent Stem Cell-Based 2D/3D Approaches. | GarcΓa-LΓ³pez M et al. | β | 2021 | β |
| Highly efficient magnetic labelling allows MRI tracking of the homing of stem cell-derived extracellular vesicles following systemic delivery. | Han Z et al. | β | 2021 | β |
| hiPSCs for predictive modelling of neurodegenerative diseases: dreaming the possible. | Rivetti di Val Cervo P et al. | β | 2021 | β |
| Human biomimetic liver microphysiology systems in drug development and precision medicine. | Gough A et al. | β | 2021 | β |
| Human Induced Pluripotent Stem Cell as a Disease Modeling and Drug Development Platform-A Cardiac Perspective. | Bekhite MM et al. | β | 2021 | β |
| Human iPSC-based neurodevelopmental models of globoid cell leukodystrophy uncover patient- and cell type-specific disease phenotypes. | Mangiameli E et al. | β | 2021 | β |
| Human lung-on-chips: Advanced systems for respiratory virus models and assessment of immune response. | Saygili E et al. | β | 2021 | β |
| Hutchinson-Gilford progeria syndrome: Rejuvenating old drugs to fight accelerated ageing. | Guilbert SM et al. | β | 2021 | β |
| Hybrid SMART spheroids to enhance stem cell therapy for CNS injuries. | Rathnam C et al. | β | 2021 | β |
| Hypothalamus and neuroendocrine diseases: The use of human-induced pluripotent stem cells for disease modeling. | de Souza Santos R et al. | β | 2021 | β |
| Imaging of cell-based therapy using <sup>89</sup>Zr-oxine <i>ex vivo</i> cell labeling for positron emission tomography. | Kurebayashi Y et al. | β | 2021 | β |
| Immune and Genome Engineering as the Future of Transplantable Tissue. | Elisseeff J et al. | β | 2021 | β |
| Implications of genetic variation in the complement system in age-related macular degeneration. | de Jong S et al. | β | 2021 | β |
| Improved safety of induced pluripotent stem cell-derived antigen-presenting cell-based cancer immunotherapy. | Mashima H et al. | β | 2021 | β |
| Inborn errors of metabolism: Lessons from iPSC models. | EscribΓ‘ R et al. | β | 2021 | β |
| Induced pluripotent stem cells for 2D and 3D modelling the biological basis of schizophrenia and screening possible therapeutics. | Tomaskovic-Crook E et al. | β | 2021 | β |
| Induced Pluripotent Stem Cells (iPSCs) and Gene Therapy: A New Era for the Treatment of Neurological Diseases. | Paolini Sguazzi G et al. | β | 2021 | β |
| Induced Pluripotent Stem Cells (iPSCs) Technology: Potential Targets for Depression. | Colpo GD et al. | β | 2021 | β |
| Induced Pluripotent Stem Cells to Model Juvenile Myelomonocytic Leukemia: New Perspectives for Preclinical Research. | Wehbe Z et al. | β | 2021 | β |
| Induced pluripotent stem cell technology for spinal cord injury: a promising alternative therapy. | Li Y et al. | β | 2021 | β |
| Induction of muscle-regenerative multipotent stem cells from human adipocytes by PDGF-AB and 5-azacytidine. | Yeola A et al. | β | 2021 | β |
| Integrated, automated maintenance, expansion and differentiation of 2D and 3D patient-derived cellular models for high throughput drug screening. | Boussaad I et al. | β | 2021 | β |
| iPSC screening for drug repurposing identifies anti-RNA virus agents modulating host cell susceptibility. | Imamura K et al. | β | 2021 | β |
| Isolation of neural stem and oligodendrocyte progenitor cells from the brain of live rats. | McClenahan F et al. | β | 2021 | β |
| Label-Free Quantification of Cell Cycle Synchronicity of Human Neural Progenitor Cells Based on Electrophysiology Phenotypes. | Honrado C et al. | β | 2021 | β |
| Leukemic stem cells shall be searched in the bone marrow before "tyrosine kinase inhibitor-discontinuation" in chronic myeloid leukemia. | Ilhan O et al. | β | 2021 | β |
| Long-term survival of transplanted induced pluripotent stem cell-derived neurospheres with nerve conduit into sciatic nerve defects in immunosuppressed mice. | Yokoi T et al. | β | 2021 | β |
| Microfluidic and Nanofluidic Intracellular Delivery. | Hur J et al. | β | 2021 | β |
| Microfluidics as efficient technology for the isolation and characterization of stem cells. | Aghlmandi A et al. | β | 2021 | β |
| Microphysiological systems to study tumor-stroma interactions in brain cancer. | Neves ER et al. | β | 2021 | β |
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| Modeling neurological disorders using brain organoids. | Zhang DY et al. | β | 2021 | β |
| Modeling of lung phenotype of Hermansky-Pudlak syndrome type I using patient-specific iPSCs. | Suezawa T et al. | β | 2021 | β |
| Modeling Sporadic Alzheimer's Disease in Human Brain Organoids under Serum Exposure. | Chen X et al. | β | 2021 | β |
| Modelling Mitochondrial Disease in Human Pluripotent Stem Cells: What Have We Learned? | McKnight CL et al. | β | 2021 | β |
| Molecular Mechanisms behind Inherited Neurodegeneration of the Optic Nerve. | Maresca A et al. | β | 2021 | β |
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| mRNA - A game changer in regenerative medicine, cell-based therapy and reprogramming strategies. | Chabanovska O et al. | β | 2021 | β |
| Natural products in drug discovery: advances and opportunities. | Atanasov AG et al. | β | 2021 | β |
| Neural In Vitro Models for Studying Substances Acting on the Central Nervous System. | Fritsche E et al. | β | 2021 | β |
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| Novel fragile X syndrome 2D and 3D brain models based on human isogenic FMRP-KO iPSCs. | Brighi C et al. | β | 2021 | β |
| Optimal Expression of the Envelope Glycoprotein of Orthobornaviruses Determines the Production of Mature Virus Particles. | Sakai M et al. | β | 2021 | β |
| Overcoming bioprocess bottlenecks in the large-scale expansion of high-quality hiPSC aggregates in vertical-wheel stirred suspension bioreactors. | Borys BS et al. | β | 2021 | β |
| Overcoming epigenetic roadblocks. | Raas MWD et al. | β | 2021 | β |
| Patient-Derived Induced Pluripotent Stem Cell Models for Phenotypic Screening in the Neuronal Ceroid Lipofuscinoses. | Morsy A et al. | β | 2021 | β |
| Patient-Derived Induced Pluripotent Stem Cells (iPSCs) and Cerebral Organoids for Drug Screening and Development in Autism Spectrum Disorder: Opportunities and Challenges. | Villa C et al. | β | 2021 | β |
| Patient-specific iPSC-derived endothelial cells reveal aberrant p38 MAPK signaling in atypical hemolytic uremic syndrome. | Zhou D et al. | β | 2021 | β |
| Perspective: Why and How Ubiquitously Distributed, Vascular-Associated, Pluripotent Stem Cells in the Adult Body (vaPS Cells) Are the Next Generation of Medicine. | Alt EU et al. | β | 2021 | β |
| Pluripotent stem cells in developmental biology. | Ikeya M et al. | β | 2021 | β |
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| Potential of Drug Efficacy Evaluation in Lung and Kidney Cancer Models Using Organ-on-a-Chip Technology. | Hwang SH et al. | β | 2021 | β |
| Progress and Challenges in the Use of a Liver-on-a-Chip for Hepatotropic Infectious Diseases. | Kulkeaw K et al. | β | 2021 | β |
| Recent Advances in Models of Immune-Mediated Drug-Induced Liver Injury. | Tasnim F et al. | β | 2021 | β |
| Regenerative medicine for the hepatobiliary system: A review. | Huang Y et al. | β | 2021 | β |
| Regulatory considerations for developing a phase I investigational new drug application for autologous induced pluripotent stem cells-based therapy product. | Jha BS et al. | β | 2021 | β |
| Requirement of direct contact between chondrocytes and macrophages for the maturation of regenerative cartilage. | Kanda K et al. | β | 2021 | β |
| Self-assembly of differentiated progenitor cells facilitates spheroid human skin organoid formation and planar skin regeneration. | Ebner-Peking P et al. | β | 2021 | β |
| SETD1A Mediated H3K4 Methylation and Its Role in Neurodevelopmental and Neuropsychiatric Disorders. | Wang S et al. | β | 2021 | β |
| Single-cell transfection technologies for cell therapies and gene editing. | Duckert B et al. | β | 2021 | β |
| SIRT2 regulates mitochondrial dynamics and reprogramming via MEK1-ERK-DRP1 and AKT1-DRP1 axes. | Cha Y et al. | β | 2021 | β |
| Stem Cell-Based Therapies: What Interventional Radiologists Need to Know. | Yu H et al. | β | 2021 | β |
| Stem cell therapies and benefaction of somatic cell nuclear transfer cloning in COVID-19 era. | Singh B et al. | β | 2021 | β |
| Suspension Culture of Human Induced Pluripotent Stem Cells in Single-Use Vertical-Wheelβ’ Bioreactors Using Aggregate and Microcarrier Culture Systems. | Nogueira DES et al. | β | 2021 | β |
| Targeting Ξ±-Synuclein in Parkinson's Disease by Induced Pluripotent Stem Cell Models. | Spathopoulou A et al. | β | 2021 | β |
| The Application of Induced Pluripotent Stem Cells Against Liver Diseases: An Update and a Review. | Zhang L et al. | β | 2021 | β |
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| The Gut-Brain Axis in Inflammatory Bowel Disease-Current and Future Perspectives. | GΓΌnther C et al. | β | 2021 | β |
| The Potential of Induced Pluripotent Stem Cells to Test Gene Therapy Approaches for Neuromuscular and Motor Neuron Disorders. | Cappella M et al. | β | 2021 | β |
| Therapeutic genome editing in cardiovascular diseases. | Nishiga M et al. | β | 2021 | β |
| Therapeutic Options in Hereditary Optic Neuropathies. | Amore G et al. | β | 2021 | β |
| The relevance of mitochondrial DNA variants fluctuation during reprogramming and neuronal differentiation of human iPSCs. | Palombo F et al. | β | 2021 | β |
| The science and engineering of stem cell-derived organoids-examples from hepatic, biliary, and pancreatic tissues. | Ogoke O et al. | β | 2021 | β |
| The vascular niche in next generation microphysiological systems. | Ewald ML et al. | β | 2021 | β |
| Tissue Engineering for Musculoskeletal Regeneration and Disease Modeling. | Li Z et al. | β | 2021 | β |
| Toward Developing Immunocompetent Diabetic Foot Ulcer-on-a-Chip Models for Drug Testing. | Ejiugwo M et al. | β | 2021 | β |
| Transgene Delivery to Human Induced Pluripotent Stem Cells Using Nanoparticles. | Yamoah MA et al. | β | 2021 | β |
| Tumour microenvironment 3D-modelling: simplicity to complexity and back again. | Carter EP et al. | β | 2021 | β |
| Ultrahigh Efficiency and Minimalist Intracellular Delivery of Macromolecules Mediated by Latent-Photothermal Surfaces. | Tang H et al. | β | 2021 | β |
| Umbilical cord blood cells for the treatment of preterm white matter injury: Potential effects and treatment options. | Qiu H et al. | β | 2021 | β |
| Virology of SARS-CoV-2 and management of nCOVID-19 utilizing immunomodulation properties of human mesenchymal stem cells-a literature review. | Sachdeva K et al. | β | 2021 | β |
| A Cell-Autonomous Signature of Dysregulated Protein Phosphorylation Underlies Muscle Insulin Resistance in Type 2 Diabetes. | Batista TM et al. | β | 2020 | β |
| A collection of three integration-free iPSCs derived from old male and female healthy subjects. | RodrΓguez-Traver E et al. | β | 2020 | β |
| A Droplet Microfluidic System to Fabricate Hybrid Capsules Enabling Stem Cell Organoid Engineering. | Liu H et al. | β | 2020 | β |
| Advances in regenerative therapy: A review of the literature and future directions. | Ntege EH et al. | β | 2020 | β |
| A Guide to Understanding "State-of-the-Art" Basic Research Techniques in Anesthesiology. | Obal D et al. | β | 2020 | β |
| A mechanical non-enzymatic method for isolation of mouse embryonic fibroblasts. | Hosseini V et al. | β | 2020 | β |
| A Multiplexed Barcodelet Single-Cell RNA-Seq Approach Elucidates Combinatorial Signaling Pathways that Drive ESC Differentiation. | Yeo GHT et al. | β | 2020 | β |
| Animal Model Contributions to Congenital Metabolic Disease. | Moro CA et al. | β | 2020 | β |
| An induced pluripotent stem cell model of Fanconi anemia reveals mechanisms of p53-driven progenitor cell differentiation. | Marion W et al. | β | 2020 | β |
| An in situ collagen-HA hydrogel system promotes survival and preserves the proangiogenic secretion of hiPSC-derived vascular smooth muscle cells. | Dash BC et al. | β | 2020 | β |
| A novel human pluripotent stem cell-based assay to predict developmental toxicity. | Lauschke K et al. | β | 2020 | β |
| Application of CRISPR/Cas9 to human-induced pluripotent stem cells: from gene editing to drug discovery. | De Masi C et al. | β | 2020 | β |
| Applications of 3D Bioprinted-Induced Pluripotent Stem Cells in Healthcare. | Soman SS et al. | β | 2020 | β |
| Applications of Functional Genomics for Drug Discovery. | Kabadi A et al. | β | 2020 | β |
| A quantum thermometric sensing and analysis system using fluorescent nanodiamonds for the evaluation of living stem cell functions according to intracellular temperature. | Yukawa H et al. | β | 2020 | β |
| A roadmap for neurodevelopmental disease modeling for non-stem cell biologists. | Ernst C | β | 2020 | β |
| A Systematic Analysis Revealed the Potential Gene Regulatory Processes of ATRA-Triggered Neuroblastoma Differentiation and Identified a Novel RA Response Sequence in the <i>NTRK2</i> Gene. | Guo L et al. | β | 2020 | β |
| Biallelic correction of sickle cell disease-derived induced pluripotent stem cells (iPSCs) confirmed at the protein level through serum-free iPS-sac/erythroid differentiation. | Haro-Mora JJ et al. | β | 2020 | β |
| Bioactive Lipid Signaling in Cardiovascular Disease, Development, and Regeneration. | Wasserman AH et al. | β | 2020 | β |
| Bioprocess Technologies that Preserve the Quality of iPSCs. | Polanco A et al. | β | 2020 | β |
| Brain organoids: Human 3D models to investigate neuronal circuits assembly, function and dysfunction. | Tambalo M et al. | β | 2020 | β |
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| BrainPhys neuronal medium optimized for imaging and optogenetics in vitro. | Zabolocki M et al. | β | 2020 | β |
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| Carbon Fibers as a New Type of Scaffold for Midbrain Organoid Development. | Tejchman A et al. | β | 2020 | β |
| CD49f Is a Novel Marker of Functional and Reactive Human iPSC-Derived Astrocytes. | Barbar L et al. | β | 2020 | β |
| Cell-Based Therapy for Canavan Disease Using Human iPSC-Derived NPCs and OPCs. | Feng L et al. | β | 2020 | β |
| Cellular reprogramming: Mathematics meets medicine. | Dotson GA et al. | β | 2020 | β |
| Challenges and Opportunities for Translation ofΒ Therapies to Improve Cognition in DownΒ Syndrome. | Lee SE et al. | β | 2020 | β |
| Challenges and Solutions for Commercial Scale Manufacturing of Allogeneic Pluripotent Stem Cell Products. | Lee B et al. | β | 2020 | β |
| Combination of In Situ Lcn2 pRNA-RNAi Nanotherapeutics and iNSC Transplantation Ameliorates Experimental SCI in Mice. | Braga A et al. | β | 2020 | β |
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| COVID-19 and cardiovascular disease: from basic mechanisms to clinical perspectives. | Nishiga M et al. | β | 2020 | β |
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| CRISPR/Cas9-mediated Knockout of the Neuropsychiatric Risk Gene KCTD13 Causes Developmental Deficits in Human Cortical Neurons Derived from Induced Pluripotent Stem Cells. | Kizner V et al. | β | 2020 | β |
| Current state of stem cell-based therapies: an overview. | Aly RM | β | 2020 | β |
| Current understanding of and emerging treatment options for spinal muscular atrophy with respiratory distress type 1 (SMARD1). | Perego MGL et al. | β | 2020 | β |
| Cystic renal-epithelial derived induced pluripotent stem cells from polycystic kidney disease patients. | Kenter AT et al. | β | 2020 | β |
| Deconstructing Neurogenesis, Transplantation and Genome-Editing as Neural Repair Strategies in Brain Disease. | Chohan MO | β | 2020 | β |
| Derivation of endothelial cells from porcine induced pluripotent stem cells by optimized single layer culture system. | Wei R et al. | β | 2020 | β |
| Development of genetic quality tests for good manufacturing practice-compliant induced pluripotent stem cells and their derivatives. | Jo HY et al. | β | 2020 | β |
| Development of Physiologically Responsive Human iPSC-Derived Intestinal Epithelium to Study Barrier Dysfunction in IBD. | Gleeson JP et al. | β | 2020 | β |
| Differentiation of human airway-organoids from induced pluripotent stem cells (iPSCs). | Wang R et al. | β | 2020 | β |
| Direct Lineage Reprogramming: Harnessing Cell Plasticity between Liver and Pancreas. | Ruzittu S et al. | β | 2020 | β |
| Dissecting transcriptomic signatures of neuronal differentiation and maturation using iPSCs. | Burke EE et al. | β | 2020 | β |
| DNA methylation and the core pluripotency network. | Shanak S et al. | β | 2020 | β |
| Donor information in research and drug evaluation with induced pluripotent stem cells (iPSCs). | Orzechowski M et al. | β | 2020 | β |
| Emulating Human Tissues and Organs: A Bioprinting Perspective Toward Personalized Medicine. | Fonseca AC et al. | β | 2020 | β |
| Engineered tissues and strategies to overcome challenges in drug development. | Khalil AS et al. | β | 2020 | β |
| Engineering Biomaterials with Micro/Nanotechnologies for Cell Reprogramming. | Fang J et al. | β | 2020 | β |
| Experimental Models to Study Autism Spectrum Disorders: hiPSCs, Rodents and Zebrafish. | Pensado-LΓ³pez A et al. | β | 2020 | β |
| Exploring the mechanisms underlying excitation/inhibition imbalance in human iPSC-derived models of ASD. | Culotta L et al. | β | 2020 | β |
| Extracellular matrix and biomimetic engineering microenvironment for neuronal differentiation. | Jain D et al. | β | 2020 | β |
| Extracellular Vesicles from Skeletal Muscle Cells Efficiently Promote Myogenesis in Induced Pluripotent Stem Cells. | Baci D et al. | β | 2020 | β |
| Fluorescent indicators for continuous and lineage-specific reporting of cell-cycle phases in human pluripotent stem cells. | Chang Y et al. | β | 2020 | β |
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| Gene Editing in Human Pluripotent Stem Cells: Recent Advances for Clinical Therapies. | ΕiΕli HB et al. | β | 2020 | β |
| Generation of Complete Multi-Cell Type Lung Organoids From Human Embryonic and Patient-Specific Induced Pluripotent Stem Cells for Infectious Disease Modeling and Therapeutics Validation. | Leibel SL et al. | β | 2020 | β |
| Genetic, clinical, molecular, and pathogenic aspects of the South Asian-specific polymorphic MYBPC3<sup>Ξ25bp</sup> variant. | Arif M et al. | β | 2020 | β |
| Genome-edited adult stem cells: Next-generation advanced therapy medicinal products. | Benabdellah K et al. | β | 2020 | β |
| Genomic integrity of human induced pluripotent stem cells across nine studies in the NHLBI NextGen program. | Kanchan K et al. | β | 2020 | β |
| Hepatic spheroids derived from human induced pluripotent stem cells in bio-artificial liver rescue porcine acute liver failure. | Chen S et al. | β | 2020 | β |
| Hepatocyte-like cells derived from induced pluripotent stem cells: A versatile tool to understand lipid disorders. | Larsen LE et al. | β | 2020 | β |
| High-throughput Preparation of DNA, RNA, and Protein from Cryopreserved Human iPSCs for Multi-omics Analysis. | Zhang JX et al. | β | 2020 | β |
| hiPSC-Derived Neurons Provide a Robust and Physiologically Relevant <i>In Vitro</i> Platform to Test Botulinum Neurotoxins. | Lamotte JD et al. | β | 2020 | β |
| Human Caesarean scar-derived feeder cells: a novel feeder cell type for culturing human pluripotent stem cells without exogenous basic fibroblast growth factor supplementation. | Pavarajarn W et al. | β | 2020 | β |
| Human-Induced Pluripotent Stem Cell Culture Methods Under cGMP Conditions. | Rivera T et al. | β | 2020 | β |
| Human induced pluripotent stem cell line with genetically encoded fluorescent voltage indicator generated via CRISPR for action potential assessment post-cardiogenesis. | Sun YH et al. | β | 2020 | β |
| Human Induced Pluripotent Stem Cell Models of Neurodegenerative Disorders for Studying the Biomedical Implications of Autophagy. | Seranova E et al. | β | 2020 | β |
| Human-induced pluripotent stem cells as a model for studying sporadic Alzheimer's disease. | Riemens RJM et al. | β | 2020 | β |
| Human induced pluripotent stem cells as a tool for disease modeling and drug screening for COVID-19. | Nolasco P et al. | β | 2020 | β |
| Human Menstrual Blood-Derived Mesenchymal Cells Improve Mouse Embryonic Development. | GonΓ§alves MF et al. | β | 2020 | β |
| Immune reaction and regulation in transplantation based on pluripotent stem cell technology. | Otsuka R et al. | β | 2020 | β |
| Induced Pluripotent Stem Cell Meets Severe Combined Immunodeficiency. | Kouchaki R et al. | β | 2020 | β |
| iPSC-Derived Liver Organoids: A Journey from Drug Screening, to Disease Modeling, Arriving to Regenerative Medicine. | Olgasi C et al. | β | 2020 | β |
| iPSC for modeling neurodegenerative disorders. | Valadez-Barba V et al. | β | 2020 | β |
| iPSC modeling of young-onset Parkinson's disease reveals a molecular signature of disease and novel therapeutic candidates. | Laperle AH et al. | β | 2020 | β |
| Magnetic heating of nanoparticles as a scalable cryopreservation technology for human induced pluripotent stem cells. | Ito A et al. | β | 2020 | β |
| Mesenchymal stem cell mediates cardiac repair through autocrine, paracrine and endocrine axes. | Sid-Otmane C et al. | β | 2020 | β |
| Microfluidics-enabled 96-well perfusion system for high-throughput tissue engineering and long-term all-optical electrophysiology. | Wei L et al. | β | 2020 | β |
| Microphysiological Modeling of the Human Endometrium. | Campo H et al. | β | 2020 | β |
| Misconnecting the dots: altered mitochondrial protein-protein interactions and their role in neurodegenerative disorders. | Zilocchi M et al. | β | 2020 | β |
| Modeling Brain Disorders Using Induced Pluripotent Stem Cells. | Vadodaria KC et al. | β | 2020 | β |
| Modeling Cardiac Disease Mechanisms Using Induced Pluripotent Stem Cell-Derived Cardiomyocytes: Progress, Promises and Challenges. | Parrotta EI et al. | β | 2020 | β |
| Modeling Inflammation on Neurodevelopmental Disorders Using Pluripotent Stem Cells. | Freitas BC et al. | β | 2020 | β |
| Modeling MyD88 Deficiency <i>In Vitro</i> Provides New Insights in Its Function. | Craig-Mueller N et al. | β | 2020 | β |
| Modeling neuropsychiatric disorders using human induced pluripotent stem cells. | Wang M et al. | β | 2020 | β |
| Multiparametric Assays for Accelerating Early Drug Discovery. | Herholt A et al. | β | 2020 | β |
| Multi-platform NMR Study of Pluripotent Stem Cells Unveils Complementary Metabolic Signatures towards Differentiation. | Elena-Herrmann B et al. | β | 2020 | β |
| Neuronal Differentiation of Induced Pluripotent Stem Cells from Schizophrenia Patients in Two-Dimensional and in Three-Dimensional Cultures Reveals Increased Expression of the Kv4.2 Subunit DPP6 That Contributes to Decreased Neuronal Activity. | Naujock M et al. | β | 2020 | β |
| New and potential strategies for the treatment of PMM2-CDG. | GΓ‘mez A et al. | β | 2020 | β |
| Optimized serial expansion of human induced pluripotent stem cells using low-density inoculation to generate clinically relevant quantities in vertical-wheel bioreactors. | Borys BS et al. | β | 2020 | β |
| Patient and Disease-Specific Induced Pluripotent Stem Cells for Discovery of Personalized Cardiovascular Drugs and Therapeutics. | Paik DT et al. | β | 2020 | β |
| Pipeline for the Generation and Characterization of Transgenic Human Pluripotent Stem Cells Using the CRISPR/Cas9 Technology. | MiannΓ© J et al. | β | 2020 | β |
| Potential of transposon-mediated cellular reprogramming towards cell-based therapies. | Kumar D et al. | β | 2020 | β |
| Production of Human Pluripotent Stem Cell-Derived Hepatic Cell Lineages and Liver Organoids: Current Status and Potential Applications. | Cotovio JP et al. | β | 2020 | β |
| Progress of Induced Pluripotent Stem Cell Technologies to Understand Genetic Epilepsy. | Sterlini B et al. | β | 2020 | β |
| Propagation of human prostate tissue from induced pluripotent stem cells. | Hepburn AC et al. | β | 2020 | β |
| Prospects of Directly Reprogrammed Adult Human Neurons for Neurodegenerative Disease Modeling and Drug Discovery: iN vs. iPSCs Models. | Zhang Y et al. | β | 2020 | β |
| Proteomics of Long-Lived Mammals. | Tombline G et al. | β | 2020 | β |
| Quality Standards of Stem Cell Sources for Clinical Treatment of Neurodegenerative Diseases. | Han F et al. | β | 2020 | β |
| Recapitulating developmental mechanisms for retinal regeneration. | Ahmad I et al. | β | 2020 | β |
| Recent progress in translational engineered in vitro models of the central nervous system. | Nikolakopoulou P et al. | β | 2020 | β |
| Reduced graphene oxide-GelMA-PCL hybrid nanofibers for peripheral nerve regeneration. | Fang X et al. | β | 2020 | β |
| Regenerative hepatology: In the quest for a modern prometheus? | Papatheodoridi M et al. | β | 2020 | β |
| Reimagining What We Measure in Atherosclerosis-a "Phenotype Stack". | MacRae CA et al. | β | 2020 | β |
| Safe scarless cassette-free selection of genome-edited human pluripotent stem cells using temporary drug resistance. | Kim KT et al. | β | 2020 | β |
| Scaffolds Functionalized with Matrix from Induced Pluripotent Stem Cell Fibroblasts for Diabetic Wound Healing. | Santarella F et al. | β | 2020 | β |
| Shaking culture enhances chondrogenic differentiation of mouse induced pluripotent stem cell constructs. | Limraksasin P et al. | β | 2020 | β |
| Single-cell RNA sequencing in cardiovascular development, disease and medicine. | Paik DT et al. | β | 2020 | β |
| STAT3 modulates reprogramming efficiency of human somatic cells; insights from autosomal dominant Hyper IgE syndrome caused by STAT3 mutations. | Yu Z et al. | β | 2020 | β |
| State-of-the-Art Technology of Model Organisms for Current Human Medicine. | Konno M et al. | β | 2020 | β |
| Stem Cell Modeling: A Promising New Avenue for Young-Onset PD Research. | Zhang W et al. | β | 2020 | β |
| Strategies to achieve immune tolerance in allogeneic solid organ transplantation. | Zeng S et al. | β | 2020 | β |
| Surface-Mediated Intracellular Delivery by Physical Membrane Disruption. | Qu Y et al. | β | 2020 | β |
| Synthetic alternatives to Matrigel. | Aisenbrey EA et al. | β | 2020 | β |
| Targeting cell plasticity for regeneration: From in vitro to in vivo reprogramming. | Romanazzo S et al. | β | 2020 | β |
| Technical Feasibility and Physiological Relevance of Hypoxic Cell Culture Models. | Pavlacky J et al. | β | 2020 | β |
| TFAP2C facilitates somatic cell reprogramming by inhibiting c-Myc-dependent apoptosis and promoting mesenchymal-to-epithelial transition. | Wang Y et al. | β | 2020 | β |
| The H-Y Antigen in Embryonic Stem Cells Causes Rejection in Syngeneic Female Recipients. | Hu X et al. | β | 2020 | β |
| The Progress and Clinical Application of Breast Cancer Organoids. | Yu J et al. | β | 2020 | β |
| Towards the clinical translation of optogenetic skeletal muscle stimulation. | Gundelach LA et al. | β | 2020 | β |
| Translational Roadmap for the Organs-on-a-Chip Industry toward Broad Adoption. | Allwardt V et al. | β | 2020 | β |
| Transplanted Human Induced Pluripotent Stem Cell-Derived Neurons Wire and Fire with Balanced Excitation-Inhibition in Rat Cortex. | Carney RSE | β | 2020 | β |
| Tumorigenic and Immunogenic Properties of Induced Pluripotent Stem Cells: a Promising Cancer Vaccine. | Qiao Y et al. | β | 2020 | β |
| Universal assembly instructions for the placenta. | Watts JL et al. | β | 2020 | β |
| Use of Stem Cell Extracellular Vesicles as a "Holistic" Approach to CNS Repair. | Branscome H et al. | β | 2020 | β |
| Using induced pluripotent stem cell neuronal models to study neurodegenerative diseases. | Zhang X et al. | β | 2020 | β |
| Variable Outcomes in Neural Differentiation of Human PSCs Arise from Intrinsic Differences in Developmental Signaling Pathways. | Strano A et al. | β | 2020 | β |
| Vascular Microphysiological Systems to Model Diseases. | Zhang Q et al. | β | 2020 | β |
| Versatility of Induced Pluripotent Stem Cells (iPSCs) for Improving the Knowledge on Musculoskeletal Diseases. | Sanjurjo-RodrΓguez C et al. | β | 2020 | β |
| When glia meet induced pluripotent stem cells (iPSCs). | Li L et al. | β | 2020 | β |
| A biomaterials approach to Schwann cell development in neural tissue engineering. | Lotfi L et al. | β | 2019 | β |
| A combined hiPSC-derived endothelial cell and in vitro microfluidic platform for assessing biomaterial-based angiogenesis. | Natividad-Diaz SL et al. | β | 2019 | β |
| Advances in Microfluidic Blood-Brain Barrier (BBB) Models. | Oddo A et al. | β | 2019 | β |
| Aging: A cell source limiting factor in tissue engineering. | Khorraminejad-Shirazi M et al. | β | 2019 | β |
| A glomerulus-on-a-chip to recapitulate the human glomerular filtration barrier. | Petrosyan A et al. | β | 2019 | β |
| A Hepatic Scaffold from Decellularized Liver Tissue: Food for Thought. | Croce S et al. | β | 2019 | β |
| A high-throughput screening and computation platform for identifying synthetic promoters with enhanced cell-state specificity (SPECS). | Wu MR et al. | β | 2019 | β |
| A human-on-a-chip approach to tackling rare diseases. | de Mello CPP et al. | β | 2019 | β |
| Assessing the therapeutic potential of Graptopetalum paraguayense on Alzheimer's disease using patient iPSC-derived neurons. | Wu PC et al. | β | 2019 | β |
| Brain organoids as a model system for human neurodevelopment and disease. | Setia H et al. | β | 2019 | β |
| Brain Organoids as Tools for Modeling Human Neurodevelopmental Disorders. | Adams JW et al. | β | 2019 | β |
| Brown-Like Adipocyte Progenitors Derived from Human iPS Cells: A New Tool for Anti-obesity Drug Discovery and Cell-Based Therapy? | Yao X et al. | β | 2019 | β |
| Cell death assays for neurodegenerative disease drug discovery. | Linsley JW et al. | β | 2019 | β |
| Cholesterol Metabolism Is a Druggable Axis that Independently Regulates Tau and Amyloid-Ξ² in iPSC-Derived Alzheimer's Disease Neurons. | van der Kant R et al. | β | 2019 | β |
| Chronic myeloid leukemia stem cells. | Houshmand M et al. | β | 2019 | β |
| Collagen vitrigel promotes hepatocytic differentiation of induced pluripotent stem cells into functional hepatocyte-like cells. | Nakai S et al. | β | 2019 | β |
| Conditional Reprogramming for Patient-Derived Cancer Models and Next-Generation Living Biobanks. | Palechor-Ceron N et al. | β | 2019 | β |
| Constructing and Deconstructing Cancers using Human Pluripotent Stem Cells and Organoids. | Smith RC et al. | β | 2019 | β |
| Contribution of induced pluripotent stem cell technologies to the understanding of cellular phenotypes in schizophrenia. | Balan S et al. | β | 2019 | β |
| Convergence of Three-Dimensional Cell Culture and Human iPS Cells: Improving Clinical Relevance in Drug Discovery. | Eglen RM | β | 2019 | β |
| Core-Shell Fibers: Design, Roles, and Controllable Release Strategies in Tissue Engineering and Drug Delivery. | Abdullah MF et al. | β | 2019 | β |
| Current Challenges of iPSC-Based Disease Modeling and Therapeutic Implications. | Doss MX et al. | β | 2019 | β |
| Differentiation of diabetic foot ulcer-derived induced pluripotent stem cells reveals distinct cellular and tissue phenotypes. | Kashpur O et al. | β | 2019 | β |
| Differentiation of Human Induced Pluripotent Stem Cells (iPSCs) into an Effective Model of Forebrain Neural Progenitor Cells and Mature Neurons. | Bell S et al. | β | 2019 | β |
| Disease Modeling and Therapeutic Strategies in CMT2A: State of the Art. | Barbullushi K et al. | β | 2019 | β |
| Drug discovery in psychopharmacology: from 2D models to cerebral organoidsβ©. | Rossetti AC et al. | β | 2019 | β |
| Drug Discovery Platform Targeting M.Β tuberculosis with Human Embryonic Stem Cell-Derived Macrophages. | Han HW et al. | β | 2019 | β |
| Drug-Induced Rhabdomyolysis Atlas (DIRA) for idiosyncratic adverse drug reaction management. | Wen Z et al. | β | 2019 | β |
| Dysregulation of the autophagic-lysosomal pathway in Gaucher and Parkinson's disease. | Pitcairn C et al. | β | 2019 | β |
| Effect of liquid flow by pipetting during medium change on deformation of hiPSC aggregates. | Kato Y et al. | β | 2019 | β |
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| Generation of Quiescent Cardiac Fibroblasts From Human Induced Pluripotent Stem Cells for In Vitro Modeling of Cardiac Fibrosis. | Zhang H et al. | β | 2019 | β |
| Glycine cleavage system determines the fate of pluripotent stem cells via the regulation of senescence and epigenetic modifications. | Tian S et al. | β | 2019 | β |
| HDAC6 Modulates Signaling Pathways Relevant to Synaptic Biology and Neuronal Differentiation in Human Stem-Cell-Derived Neurons. | Iaconelli J et al. | β | 2019 | β |
| High-Throughput Screening for Modulators of CFTR Activity Based on Genetically Engineered Cystic Fibrosis Disease-Specific iPSCs. | Merkert S et al. | β | 2019 | β |
| Human Genomic Safe Harbors and the Suicide Gene-Based Safeguard System for iPSC-Based Cell Therapy. | Kimura Y et al. | β | 2019 | β |
| Human iPS Cell-Derived Patient Tissues and 3D Cell Culture Part 1: Target Identification and Lead Optimization. | Eglen RM et al. | β | 2019 | β |
| Increased Cytotoxicity of Herpes Simplex Virus Thymidine Kinase Expression in Human Induced Pluripotent Stem Cells. | Iwasawa C et al. | β | 2019 | β |
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| Induced Pluripotent Stem Cells Reprogrammed with Three Inhibitors Show Accelerated Differentiation Potentials with High Levels of 2-Cell Stage Marker Expression. | Nishihara K et al. | β | 2019 | β |
| Insight into Mechanobiology: How Stem Cells Feel Mechanical Forces and Orchestrate Biological Functions. | Argentati C et al. | β | 2019 | β |
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| Neural differentiation of mouse induced pluripotent stem cells using cadherin gene-engineered PA6 feeder cells. | Paerhati P et al. | β | 2019 | β |
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| Peripheral artery disease: the new frontiers of imaging techniques to evaluate the evolution of regenerative medicine. | Miceli M et al. | β | 2019 | β |
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| Strategies for the expansion of human induced pluripotent stem cells as aggregates in single-use Vertical-Wheelβ’ bioreactors. | Nogueira DES et al. | β | 2019 | β |
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| Towards Precision Medicine With Human iPSCs for Cardiac Channelopathies. | Wu JC et al. | β | 2019 | β |
| Two-in-One Platform for High-Efficiency Intracellular Delivery and Cell Harvest: When a Photothermal Agent Meets a Thermoresponsive Polymer. | Wu J et al. | β | 2019 | β |
| Understanding and Modulating Immunity With Cell Reprogramming. | Pires CF et al. | β | 2019 | β |
| Universal Correction of Blood Coagulation Factor VIII in Patient-Derived Induced Pluripotent Stem Cells Using CRISPR/Cas9. | Park CY et al. | β | 2019 | β |
| Use of Human Pluripotent Stem Cells to Define Initiating Molecular Mechanisms of Cataract for Anti-Cataract Drug Discovery. | Dewi CU et al. | β | 2019 | β |
| Validation of Current Good Manufacturing Practice Compliant Human Pluripotent Stem Cell-Derived Hepatocytes for Cell-Based Therapy. | Blackford SJI et al. | β | 2019 | β |
| Various strategies to improve efficacy of stem cell transplantation in multiple sclerosis: Focus on mesenchymal stem cells and neuroprotection. | Yousefi F et al. | β | 2019 | β |
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| A human iPSC line capable of differentiating into functional macrophages expressing ZsGreen: a tool for the study and <i>in vivo</i> tracking of therapeutic cells. | Lopez-Yrigoyen M et al. | β | 2018 | β |
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| Clinical Application of iNKT Cell-mediated Anti-tumor Activity Against Lung Cancer and Head and Neck Cancer. | Takami M et al. | β | 2018 | β |
| Combining Optical Approaches with Human Inducible Pluripotent Stem Cells in G Protein-Coupled Receptor Drug Screening and Development. | Bourque K et al. | β | 2018 | β |
| Compressive Force Spectroscopy: From Living Cells to Single Proteins. | Wang J et al. | β | 2018 | β |
| Concise Review: Assessing the Genome Integrity of Human Induced Pluripotent Stem Cells: What Quality Control Metrics? | Assou S et al. | β | 2018 | β |
| Concise Review: Regulatory Influence of Sleep and Epigenetics on Adult Hippocampal Neurogenesis and Cognitive and Emotional Function. | Akers KG et al. | β | 2018 | β |
| CRISPRed Cardiomyocytes to Decrypt Variants of Uncertain Significance. | Hulot JS et al. | β | 2018 | β |
| Development of an innervated tissue-engineered skin with human sensory neurons and Schwann cells differentiated from iPS cells. | Muller Q et al. | β | 2018 | β |
| Differentiation of Glial Cells From hiPSCs: Potential Applications in Neurological Diseases and Cell Replacement Therapy. | Zheng W et al. | β | 2018 | β |
| Directing neuronal cell fate in vitro: Achievements and challenges. | Riemens RJM et al. | β | 2018 | β |
| Ectopic hTERT expression facilitates reprograming of fibroblasts derived from patients with Werner syndrome as a WS cellular model. | Wang S et al. | β | 2018 | β |
| Effects of residual H<sub>2</sub>O<sub>2</sub> on the growth of MSCs after decontamination. | Chihara R et al. | β | 2018 | β |
| Electrophysiologic Characterization of Calcium Handling in Human Induced Pluripotent Stem Cell-Derived Atrial Cardiomyocytes. | Argenziano M et al. | β | 2018 | β |
| Engineered Human Contractile Myofiber Sheets as a Platform for Studies of Skeletal Muscle Physiology. | Takahashi H et al. | β | 2018 | β |
| Epigenetic Enzymes, Age, and Ancestry Regulate the Efficiency of Human iPSC Reprogramming. | Mackey LC et al. | β | 2018 | β |
| First stem cell transplantation to regenerate human lung. | Wang S et al. | β | 2018 | β |
| Functional innate immunity restricts Hepatitis C Virus infection in induced pluripotent stem cell-derived hepatocytes. | SchΓΆbel A et al. | β | 2018 | β |
| Generation and Applications of Induced Pluripotent Stem Cell-Derived Mesenchymal Stem Cells. | Zhao C et al. | β | 2018 | β |
| Generation of Human Induced Pluripotent Stem Cells Using a Defined, Feeder-Free Reprogramming System. | Park S et al. | β | 2018 | β |
| Gene therapy clinical trials worldwide to 2017: An update. | Ginn SL et al. | β | 2018 | β |
| Genetics of Alcohol Use Disorder: A Role for Induced Pluripotent Stem Cells? | Prytkova I et al. | β | 2018 | β |
| GFAP Mutations in Astrocytes Impair Oligodendrocyte Progenitor Proliferation and Myelination in an hiPSC Model of Alexander Disease. | Li L et al. | β | 2018 | β |
| Harnessing cell pluripotency for cardiovascular regenerative medicine. | Chen H et al. | β | 2018 | β |
| Highly efficient scarless knock-in of reporter genes into human and mouse pluripotent stem cells via transient antibiotic selection. | Sluch VM et al. | β | 2018 | β |
| Highly efficient transfection of human induced pluripotent stem cells using magnetic nanoparticles. | Yamoah MA et al. | β | 2018 | β |
| Human-Induced Pluripotent Stem Cells Manufactured Using a Current Good Manufacturing Practice-Compliant Process Differentiate Into Clinically Relevant Cells From Three Germ Layers. | Shafa M et al. | β | 2018 | β |
| Human iPSC-based models highlight defective glial and neuronal differentiation from neural progenitor cells in metachromatic leukodystrophy. | Frati G et al. | β | 2018 | β |
| Human iPSC-Derived Endothelial Cells and Microengineered Organ-Chip Enhance Neuronal Development. | Sances S et al. | β | 2018 | β |
| Induced PTF1a expression in pancreatic ductal adenocarcinoma cells activates acinar gene networks, reduces tumorigenic properties, and sensitizes cells to gemcitabine treatment. | Jakubison BL et al. | β | 2018 | β |
| Inflammatory Responses and Barrier Function of Endothelial Cells Derived from Human Induced Pluripotent Stem Cells. | Halaidych OV et al. | β | 2018 | β |
| Informative three-dimensional survey of cell/tissue architectures in thick paraffin sections by simple low-vacuum scanning electron microscopy. | Sawaguchi A et al. | β | 2018 | β |
| Inhibition of miR-449a Promotes Cartilage Regeneration and Prevents Progression of Osteoarthritis in InΒ Vivo Rat Models. | Baek D et al. | β | 2018 | β |
| Integration of Lead Discovery Tactics and the Evolution of the Lead Discovery Toolbox. | Leveridge M et al. | β | 2018 | β |
| Interrupted reprogramming of alveolar type II cells induces progenitor-like cells that ameliorate pulmonary fibrosis. | Guo L et al. | β | 2018 | β |
| Interspecies chimeras. | Suchy F et al. | β | 2018 | β |
| Isolation of cancer cells with augmented spheroid-forming capability using a novel tool equipped with removable filter. | Fujibayashi E et al. | β | 2018 | β |
| Large-scale production of stem cells utilizing microcarriers: A biomaterials engineering perspective from academic research to commercialized products. | Tavassoli H et al. | β | 2018 | β |
| Loss of neural crest-associated gene FOXD1 impairs melanoma invasion and migration via RAC1B downregulation. | Wu H et al. | β | 2018 | β |
| Membrane permeabilizing amphiphilic peptide delivers recombinant transcription factor and CRISPR-Cas9/Cpf1 ribonucleoproteins in hard-to-modify cells. | Del'Guidice T et al. | β | 2018 | β |
| Mimicking Epithelial Tissues in Three-Dimensional Cell Culture Models. | Torras N et al. | β | 2018 | β |
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| Modeling Neurological Diseases With Human Brain Organoids. | Wang H | β | 2018 | β |
| Modeling Parkinson's Disease and Atypical Parkinsonian Syndromes Using Induced Pluripotent Stem Cells. | Mishima T et al. | β | 2018 | β |
| Modeling the rare diseases process in dish. | Tang W | β | 2018 | β |
| NeuroSystematics and Periodic System of Neurons: Model vs Reference Species at Single-Cell Resolution. | Moroz LL | β | 2018 | β |
| New Genetically Manipulated Mice Provide Insights Into the Development and Physiological Functions of Invariant Natural Killer T Cells. | Ren Y et al. | β | 2018 | β |
| Optogenetics in cancer drug discovery. | KieΕbus M et al. | β | 2018 | β |
| Pluripotent stem cell replacement approaches to treat type 1 diabetes. | Pellegrini S et al. | β | 2018 | β |
| Potential Use of Human Stem Cell-Derived Intestinal Organoids to Study Inflammatory Bowel Diseases. | Dotti I et al. | β | 2018 | β |
| Recapitulation of methotrexate hepatotoxicity with induced pluripotent stem cell-derived hepatocytes from patients with rheumatoid arthritis. | Kim J et al. | β | 2018 | β |
| Regenerating the kidney using human pluripotent stem cells and renal progenitors. | Becherucci F et al. | β | 2018 | β |
| Rescuing ocular development in an anophthalmic pig by blastocyst complementation. | Zhang H et al. | β | 2018 | β |
| Roadblocks in the Path of iPSC to the Clinic. | Garreta E et al. | β | 2018 | β |
| Small vessels, dementia and chronic diseases - molecular mechanisms and pathophysiology. | Horsburgh K et al. | β | 2018 | β |
| Solriamfetol for the treatment of daytime sleepiness in obstructive sleep apnea. | Abad VC et al. | β | 2018 | β |
| Stem Cells, Genome Editing, and the Path to Translational Medicine. | Soldner F et al. | β | 2018 | β |
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| Temporal Dynamics of Gene Expression During Endothelial Cell Differentiation From Human iPS Cells: A Comparison Study of Signalling Factors and Small Molecules. | Belt H et al. | β | 2018 | β |
| Ten years of progress and promise of induced pluripotent stem cells: historical origins, characteristics, mechanisms, limitations, and potential applications. | Omole AE et al. | β | 2018 | β |
| The GluN2B subunit represents a major functional determinant of NMDA receptors in human induced pluripotent stem cell-derived cortical neurons. | Neagoe I et al. | β | 2018 | β |
| The lipodystrophic hotspot lamin A p.R482W mutation deregulates the mesodermal inducer T/Brachyury and early vascular differentiation gene networks. | Briand N et al. | β | 2018 | β |
| The potential of human induced pluripotent stem cells for modelling diabetic wound healing <i>in vitro</i>. | Martin PE et al. | β | 2018 | β |
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| Unraveling of Central Nervous System Disease Mechanisms Using CRISPR Genome Manipulation. | Vesikansa A | β | 2018 | β |
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