Detecting gene-environment interactions in genome-wide association data.

paper Cited Public

Authors: Engelman, Corinne D; Baurley, James W; Chiu, Yen-Feng; Joubert, Bonnie R; Lewinger, Juan P; Maenner, Matthew J; Murcray, Cassandra E; Shi, Gang; Gauderman, W James
Year: 2009
Journal: Genetic epidemiology
PMID: 19924704
DOI: 10.1002/gepi.20475
PMCID: PMC2924567

#	Section	Preview
20	SUMMARY AND CONCLUSIONS	errors (false positives and false negatives, respectively). Alternately, Maenner et al. [2009]…
21	SUMMARY AND CONCLUSIONS	Accurately quantifying environmental exposures at the individual level is a challenge that is widely…
22	SUMMARY AND CONCLUSIONS	per day across visits, or last known smoking status). More complete measurements of environmental…
23	SUMMARY AND CONCLUSIONS	The FHS presented additional challenges beyond that of multiple comparisons and measurement of…
24	SUMMARY AND CONCLUSIONS	et al. [2009] used a two-level factor analysis for longitudinal data. Maenner et al. and Gu et al.…
25	SUMMARY AND CONCLUSIONS	As discussed previously, because tests for G×E interaction are generally less powerful than those…
26	SUMMARY AND CONCLUSIONS	test that has been shown to be a more robust choice to detect markers involved in disease risk…
27	SUMMARY AND CONCLUSIONS	of the case-only design and unbiasedness of a case-control design. By combining case-control and…
28	SUMMARY AND CONCLUSIONS	Although only one of the Group 10 contributions tested for population stratification [Arya et al.,…
29	SUMMARY AND CONCLUSIONS	Finally, analyzing G×E interactions can be computationally intensive. For dichotomous traits,…
30	SUMMARY AND CONCLUSIONS	3 seconds, both using SAS PROC MIXED. Due to the parallel nature of the genome-wide scan, cluster…
31	SUMMARY AND CONCLUSIONS	The analysis of G×E interaction is likely to be of increasing importance as researchers attempt to…
32	SUMMARY AND CONCLUSIONS	testing G×E interactions, for example, jointly testing for a main and interaction effect, testing…

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In this knowledge base

Title	Year	PMID
Gene-environment interaction in psychological traits and disorders.	2011	21219196

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