Adolescent development of the reward system.
- Authors
- Galvan, Adriana
- Year
- 2010
- Journal
- Frontiers in human neuroscience
- PMID
- 20179786
- DOI
- 10.3389/neuro.09.006.2010
- PMCID
- PMC2826184
Adolescence is a developmental period characterized by increased reward-seeking behavior. Investigators have used functional magnetic resonance imaging (fMRI) in conjunction with reward paradigms to test two opposing hypotheses about adolescent developmental changes in the striatum, a region implicated in reward processing. One hypothesis posits that the striatum is relatively hypo-responsive to rewards during adolescence, such that heightened reward-seeking behavior is necessary to achieve the same activation as adults. Another view suggests that during adolescence the striatal reward system is hyper-responsive, which subsequently results in greater reward-seeking. While evidence for both hypotheses has been reported, the field has generally converged on this latter hypothesis based on compelling evidence. In this review, I describe the evidence to support this notion, speculate on the disparate fMRI findings and conclude with future areas of inquiry to this fascinating question.
No figures extracted from this document.
| Name | Type |
|---|---|
| 12-year-old local | cohort |
| 12-year-old children local | cohort |
| 17-year-old local | cohort |
| 17-year-old local | phenotype |
| 18-year-old local | cohort |
| 18-year-old local | phenotype |
| 19-year-old local | cohort |
| 9-year-old children local | cohort |
| addiction | phenotype |
| Adolescent cohort (ages 7-29) local | cohort |
| adolescent rats | cohort |
| adolescents | cohort |
| adolescent sample | cohort |
| adulthood | cohort |
| adult rats | cohort |
| adults | cohort |
| age | phenotype |
| age-restricted adolescent group local | cohort |
| anhedonia | phenotype |
| Appreciation of money local | phenotype |
| basal dopamine release local | phenotype |
| basal ganglia | anatomy |
| Baseline activation local | phenotype |
| behavioral responsivity local | phenotype |
| Bjork2004 local | cohort |
| Bjork et al., 2004 local | cohort |
| Blunted striatal activity local | phenotype |
| brain | anatomy |
| brain development | phenotype |
| brain function | phenotype |
| brain white matter | anatomy |
| caudate nucleus | anatomy |
| childhood | cohort |
| children | cohort |
| clinical population | cohort |
| cocaine | phenotype |
| cognitive control | phenotype |
| college students | cohort |
| D1 receptor | drug |
| depression | phenotype |
| developmental changes | phenotype |
| Developmental differences local | phenotype |
| Developmental differences in respiration local | phenotype |
| developmental populations local | cohort |
| dopamine | drug |
| Dopamine D2 receptor | drug |
| dopamine level | phenotype |
| Dopamine-related behaviors and learning local | phenotype |
| dopamine release | drug |
| Dopaminergic system | drug |
| dopamine storage pool local | phenotype |
| dopamine synthesis | phenotype |
| dopamine system local | phenotype |
| dopamine turnover | phenotype |
| DRD1 | gene |
| DRD2 | gene |
| Early-adolescence local | phenotype |
| Educational grade local | phenotype |
| Educators local | cohort |
| Ernst2005 local | cohort |
| Ernst et al., 2005 local | cohort |
| female rats | cohort |
| Fewer minutes of sleep local | phenotype |
| Financial independence local | phenotype |
| fMRI signal local | phenotype |
| frontal cortex | anatomy |
| Galvan2006 local | cohort |
| GalvΓ‘n et al., 2006 local | cohort |
| Geier et al., 2009 local | cohort |
| Gonadal hormone surges local | phenotype |
| gray matter | anatomy |
| heart rate | phenotype |
| heart rate variability | phenotype |
| High reward behaviors local | phenotype |
| High reward-seeking behavior local | phenotype |
| High school students | cohort |
| human | cohort |
| humans | cohort |
| hyper-responsive local | phenotype |
| Hypersensitivity to reward local | phenotype |
| hypo-responsive local | phenotype |
| illicit drug use | phenotype |
| impulsivity | phenotype |
| Incentives local | phenotype |
| Late-adolescence local | phenotype |
| Law local | phenotype |
| male rats | cohort |
| May et al., 2004 local | cohort |
| Mid-adolescence local | phenotype |
| midbrain | anatomy |
| Middle-adolescence local | phenotype |
| Mid- to late-twenties local | cohort |
| money | drug |
| mood disorders | phenotype |
| NAcc | anatomy |
| negative affect | phenotype |
| neural activation local | phenotype |
| Neural activation patterns local | phenotype |
| nomifensine local | drug |
| nonmonetary reward local | drug |
| novelty detection | phenotype |
| novelty seeking | phenotype |
| nucleus accumbens | anatomy |
| occipital cortex | anatomy |
| older adolescent animals local | cohort |
| orbitofrontal cortex | anatomy |
| Overproduction local | phenotype |
| parents | cohort |
| parietal cortex | anatomy |
| Passive rest local | phenotype |
| pathological gambling | phenotype |
| periadolescent rats local | cohort |
| pleasure | phenotype |
| Policy makers local | cohort |
| poor sleep quality | phenotype |
| Positive feelings local | phenotype |
| prefrontal cortex | anatomy |
| Pruning local | phenotype |
| puberty | phenotype |
| reaction time | phenotype |
| Respiratory rate local | phenotype |
| Response accuracy | phenotype |
| resting baseline local | phenotype |
| Resting baseline state local | phenotype |
| reward | phenotype |
| reward anticipation | phenotype |
| Reward magnitude local | phenotype |
| Reward outcome local | phenotype |
| reward paradigm local | phenotype |
| Reward probability local | phenotype |
| Reward-related risks local | phenotype |
| Rewards local | phenotype |
| reward sensitivity | phenotype |
| reward system | anatomy |
| risk perception local | phenotype |
| risk taking | phenotype |
| risk-taking behavior | phenotype |
| risky and reward-seeking behavior local | phenotype |
| Risky and reward-seeking behavior local | phenotype |
| rodents | cohort |
| scientists | cohort |
| self-regulation | phenotype |
| sensitivity to cocaine local | phenotype |
| sensitivity to nomifensine local | phenotype |
| sex | phenotype |
| sex hormones | drug |
| sexual maturation | phenotype |
| sleep | phenotype |
| Striatal response to reward local | phenotype |
| striatal slices local | anatomy |
| striatum | anatomy |
| sugar | drug |
| temporal lobe | anatomy |
| Typically Developing Youth local | cohort |
| vanLeijenhorst2009 local | cohort |
| van Leijenhorst et al., 2009 local | cohort |
| Ventral striatal activation deficit local | phenotype |
| ventral striatum | anatomy |
| young adolescent rats local | cohort |
| young adults | cohort |
No uploaded files.
| Citation | PMID | DOI | Status |
|---|---|---|---|
| AndersenS. L.DumontN. L.TeicherM. H. (1997). Developmental differences in dopamine synthesis inhibition by 7-OH-DPAT. Naunyn Schmiedebergs Arch. Pharmacol.356, 173β18110.1007/PL000050389272722 | β | β | β |
| AndersenS. L.GazzaraR. A. (1993). The ontogeny of apomorphine-induced alterations of neostriatal dopamine release: effects of spontaneous release. J. Neurochem.61, 2247β225510.1111/j.1471-4159.1993.tb07466.x8245975 | β | β | β |
| AndersenS. L.ThompsonA. P.KrenzelE.TeicherM. H. (2002). Pubertal changes in gonadal hormones do not underlie adolescent dopamine receptor overproduction. Psychoneuroendocrinology27, 683β69110.1016/S0306-4530(01)00069-512084661 | β | β | β |
| AndersenS. LTeicherM. H. (1999). Cyclic adenosine monophosphate (cAMP) changes dramatically across periadolescence and region. Poster presented at the meeting of the Society for Neuroscience Meeting, Miami Beach, Florida | β | β | β |
| AndersenS. LTeicherM. H. (2000). Dopamine receptor pruning in prefrontal cortex during the periadolescent period in rats. Synapse37, 167β16910.1002/1098-2396(200008)37:2<167::AID-SYN11>3.0.CO;2-B10881038 | β | β | β |
| BandettiniP. A.UngerleiderL. G. (2001). From neuron to BOLD: new connections. Nat. Neurosci.412, 864β86610.1038/nn0901-86411528412 | β | β | β |
| BencaR. M. (2004). Regulation of sleep and arousal: Introduction to part VII. Ann. N. Y. Acad. Sci.1021, 260β26110.1196/annals.1308.03015251895 | β | β | β |
| BerridgeK. C.RobinsonT. E. (1998). What is the role of dopamine in reward: hedonic impact, reward learning, or incentive salience?Brain Res. Brain Res. Rev.28, 309β36910.1016/S0165-0173(98)00019-89858756 | β | β | β |
| BjorkJ. M.KnutsonB.FongG. W.CaggianoD. M.BennettS. M.HommerD. W. (2004). Incentive-elicited brain activation in adolescents: similarities and differences from young adults. J. Neursoci.24, 1793β180210.1523/JNEUROSCI.4862-03.2004PMC673040214985419 | β | β | β |
| BlumK.BravermanE.HolderJ.LubarJ.MonastraV.MillerD.LubarJ.ChenT.ComingsD. (2000). Reward deficiency syndrome: a biogenetic model for the diagnosis and treatment of impulsive, addictive and compulsive behaviors. J. Psychoactive Drugs2, 1β11210.1080/02791072.2000.1073609911280926 | β | β | β |
| BlumK.CullJ. G.BravermanE. R.ComingsD. E. (1996). Reward deficiency syndrome. Am. Sci.84, 132β145 | β | β | β |
| BolanosC. A.GlattS. J.JacksonD. (1998). Subsensitivity to dopaminergic drugs in periadolescent rats: a behavioral and neurochemical analysis. Dev. Brain Res.111, 25β3310.1016/S0165-3806(98)00116-39804875 | β | β | β |
| BrenhouseH. C.SonntagK. C.AndersenS. L. (2008). Transient D1 dopamine receptor expression on prefrontal cortex projection neurons: relationship to enhanced motivational salience of drug cues in adolescence. J. Neurosci.28, 2375β238210.1523/JNEUROSCI.5064-07.200818322084PMC4028226 | β | β | β |
| CaseyB. J.GalvΓ‘nA.HareT. A. (2005). Changes in cerebral functional organization during cognitive development. Curr. Opin. Neurobiol.15, 239β24410.1016/j.conb.2005.03.01215831409 | β | β | β |
| CaseyB. J.GetzS.GalvΓ‘nA. (2008). The adolescent brain. Dev. Rev.28, 62β771868829210.1016/j.dr.2007.08.003PMC2500212 | β | β | β |
| CavinessV.KennedyD.RichelmeC.RademacherJ.FilipekP. (1996). The human brain age 7β11 years: a volumetric analysis based on magnetic resonance images. Cereb. Cortex6, 726β73610.1093/cercor/6.5.7268921207 | β | β | β |
| ChambersR. A.TaylorJ. R.PotenzaM. N. (2003). Developmental neurocircuitry of motivation in adolescence: a critical period of addiction vulnerability. Am. J. Psychiatry160, 1041β105210.1176/appi.ajp.160.6.104112777258PMC2919168 | β | β | β |
| CsikszentmihalyiM.LarsonR.PrescottS. (1977). The ecology of adolescent activity and experience. J. Youth Adolesc.6, 281β29410.1007/BF0213894024408457 | β | β | β |
| DahlR. E. (2004). Adolescent brain development: a period of vulnerabilities and opportunities. Ann. N. Y. Acad. Sci.1021, 1β2210.1196/annals.1308.00115251869 | β | β | β |
| DahlR. E.LewinD. S. (2002). Pathways to adolescent health sleep regulation and behavior. J. Adolesc. Health31, 175β18410.1016/S1054-139X(02)00506-212470913 | β | β | β |
| DeGraffC.ZandstraE. (1999). Sweetness intensity and pleasantness in children, adolescents and adults. Physiol. Behav.67, 513β52010.1016/S0031-9384(99)00090-610549887 | β | β | β |
| EigstiI. M.ZayasV.MischelW.ShodaY.AydukO.DadlaniM. B.DavidsonM. C.Lawrence AberJ.CaseyB. J. (2006). Predicting cognitive control from preschool to late adolescence and young adulthood. Psychol. Sci.17, 478β48410.1111/j.1467-9280.2006.01732.x16771797 | β | β | β |
| ErnstM.MuellerS. C. (2008). The adolescent brain: insights from functional neuroimaging research. Dev Neurobiol68, 729β74310.1002/dneu.2061518383544PMC2788780 | β | β | β |
| ErnstM.NelsonE. E.JazbecS. P.McClureE. B.MonkC. S.LeibenluftE.BlairJ.PineD. S. (2005). Amygdala and nucleus accumbens in responses to receipt and omission of gains in adults and adolescents. Neuroimage25, 1279β129110.1016/j.neuroimage.2004.12.03815850746 | β | β | β |
| ErnstM.RomeoR. D.AndersenS. L. (2009). Neurobiology of the development of motivated behaviors in adolescence: a window into a neural systems model. Pharmacol. Biochem. Behav.93, 199β21110.1016/j.pbb.2008.12.01319136024 | β | β | β |
| EshelN.NelsonE. E.BlairR. J.PineD. S.ErnstM. (2007). Neural substrates of choice selection in adults and adolescents: development of the ventrolateral prefrontal and anterior cingulate cortices. Neuropsychologia45, 1270β127910.1016/j.neuropsychologia.2006.10.00417118409PMC2700731 | β | β | β |
| FanJ.McCandlissB. DSommerT.RazA.PosnerM. I. (2002). Testing the efficiency and independence of attentional networks. J. Cogn. Neurosci.14, 340β34710.1162/08989290231736188611970796 | β | β | β |
| GalvΓ‘nA.HareT. A.ParraC. E.PennJ.VossH.GloverG.CaseyB. J. (2006). Earlier development of the accumbens relative to orbitofrontal cortex might underlie risk-taking behavior in adolescents. J. Neurosci.26, 6885β689210.1523/JNEUROSCI.1062-06.200616793895PMC6673830 | β | β | β |
| GalvΓ‘nA.HareT. A.VossH.GloverG.CaseyB. J. (2007). Risk-taking and the adolescent brain: who is at risk?Dev. Sci.10, 1β71728683710.1111/j.1467-7687.2006.00579.x | β | β | β |
| GeierC. F.TerwilligerR.TeslovichT.VelanovaK.LunaB. (2009). Immaturities in reward processing and its influence on inhibitory control in adolescence. Cereb. Cortex [Epub ahead of print].1987567510.1093/cercor/bhp225PMC2882823 | β | β | β |
| GieddJ. N. (2004). Structural MRI of the Adolescent Brain. Ann. N. Y. Acad. Sci.1021:7710.1196/annals.1308.00915251877 | β | β | β |
| GieddJ. N.BlumenthalJ.JeffriesN. O.CastellanosF.XLiuHZijdenbosA.PausT.EvansA. C.RapoportJ. L. (1999). Brain development during childhood and adolescence: a longitudinal MRI study. Nat. Neurosci.2, 861β86310.1038/1315810491603 | β | β | β |
| GieddJ. N.SnellJ.LangeN.RajapakseJ.CaseyB.KozuchP.VaituzisA.VaussY.HamburgerS.KaysenD.RapoportJ. L. (1996). Quantitative magnetic resonance imaging of human brain development: ages 4β18. Cereb. Cortex6 551β56010.1093/cercor/6.4.5518670681 | β | β | β |
| GogtayN.GieddJ. N.LuskL.HayashiK. M.GreensteinD.VaituzisA. C.NugentT. F.IIIHermanD. HClasenL. S.TogaA. W.RapoportJ. L.ThompsonP. M. (2004). Dynamic mapping of human cortical development during childhood through early adulthood. Proc. Natl. Acad. Sci. U.S.A.101, 8174β817910.1073/pnas.040268010115148381PMC419576 | β | β | β |
| GuyerA. E.McClure-ToneE. B.ShiffrinN. D.PineD. S.NelsonE. E. (2009). Probing the neural correlates of anticipated peer evaluation in adolescence. Child Dev.80, 1000β101510.1111/j.1467-8624.2009.01313.x19630890PMC2791675 | β | β | β |
| HagenauerM. HPerrymanJ. I.LeeT.MCarskadonM. A. (2009). Adolescent changes in the homeostatic and circadian regulation of sleep. Dev. Neurosci.31, 276β28410.1159/00021653819546564PMC2820578 | β | β | β |
| HolmS. M.ForbesE. E.RyanN. D.PhillipsM. L.TarrJ. A.RahlR. E. (2009). Reward-related brain function and sleep in pre/early pubertal and mid/ate pubertal adolescents. J. Adolesc. Health45, 319β32010.1016/j.jadohealth.2009.04.00119766936PMC2817965 | β | β | β |
| KennedyD. N.HaselgroveC.McInerneyS. (2003). MRI-based morphometric of typical and atypical brain development. Ment. Retard Dev. Disabil. Res. Rev.9, 155β16010.1002/mrdd.1007512953294 | β | β | β |
| KnutsonB.FongG. W.AdamsC. M.VarnerJ. L.HommerD. (2001). Dissociation of reward anticipation and outcome with event-related fMRI. Neuroreport12, 3683β368710.1097/00001756-200112040-0001611726774 | β | β | β |
| KoobG. F.SwerdlowN. R. (1988). The functional output of the mesolimbic dopamine system. Ann. N. Y. Acad. Sci.537, 216β22710.1111/j.1749-6632.1988.tb42108.x3059925 | β | β | β |
| KotsoniE.ByrdD.CaseyB. J. (2006). Special considerations for functional magnetic resonance imaging of pediatric populations. J. Magn. Reson. Imaging23,877β88610.1002/jmri.2057816649204PMC3014526 | β | β | β |
| KuhnenC. M.KnutsonB. (2005). The neural basis of financial risk taking. Neuron47, 763β77010.1016/j.neuron.2005.08.00816129404 | β | β | β |
| LarsonR.AsmussenL. (1991). Anger, Worry, and Hurt in Early Adolescence: An Enlarging World of Negative Emotions. New York, NY: Aldine de Gruyter | β | β | β |
| LaviolaG.MacriS.Morley-FletcherS.AdrianiW. (2003). Risk-taking behavior in adolescent mice: psychobiological determinants and early epigenetic influence. Neurosci. Biobehav. Rev.27, 19β3110.1016/S0149-7634(03)00006-X12732220 | β | β | β |
| LaviolaG.PascucciT.PierettiS. (2001). Striatal dopamine sensitization to D-amphetamine in periadolescent but not in adult rats. Pharmacol. Biochem. Behav.68, 115β12410.1016/S0091-3057(00)00430-511274716 | β | β | β |
| LogothetisN.PaulsJ.AugathM.TrinathT.OeltermannA. (2001). Neurophysiological investigation of the basis of the fMRI signal. Nature412,150β15710.1038/3508400511449264 | β | β | β |
| MaggsJ. LAlmeidaD. MGalambosN. L. (1995). Risky business: the paradoxical meaning of problem behavior for young adolescents. J. Early Adolesc.15, 344β36210.1177/0272431695015003004 | β | β | β |
| MatthewsS. C.SimmonsA. N.LaneS. D.PaulusM. P. (2004). Selective activation of the nucleus accumbens during risk-taking decision making. Neuroreport15, 2123β212710.1097/00001756-200409150-0002515486494 | β | β | β |
| MayJ. C.DelgadoM. R.DahlR. E.StengerV. A.RyanN. D.FiezJ. A.CarterC. S. (2004). Event-related functional magnetic resonance imaging of reward-related brain circuitry in children and adolescents. Biol. Psychiatry55, 359β36610.1016/j.biopsych.2003.11.00814960288 | β | β | β |
| MontagueD. M.LawlerC. P.MailmanR. B.GilmoreJ. H. (1999). Developmental regulation of the dopamine D1 receptor in human caudate and putamen. Neuropsychopharmacology21, 641β64910.1016/S0893-133X(99)00062-710516960 | β | β | β |
| MontagueP. R.BernsG. S. (2002). Neural economics and the biological substrates of valuation. Neuron36, 265β28410.1016/S0896-6273(02)00974-112383781 | β | β | β |
| MontagueP. R.HymanS. E.CohenJ. D. (2004). Computational roles for dopamine in behavioral control. Nature431,379β38710.1038/nature0301515483596 | β | β | β |
| PalaciosJ. M.CampsM.CorteR.ProbstA. (1988). Mapping dopamine receptors in the human brain. J. Neural. Transm. Suppl.27, 227β235296995210.1007/978-3-7091-8954-2_20 | β | β | β |
| PankseppJ. (1998). Affective Neuroscience. New York, Oxford University Press | β | β | β |
| PausT.KeshavanMGieddJ. N. (2008). Why do so many psychiatric disorders emerge during adolescence?Nat. Rev. Neurosci.9, 947β9571900219110.1038/nrn2513PMC2762785 | β | β | β |
| RutterM.GrahamP.ChadwickO.YuleW. (1976). Adolescent turmoil: fact or fiction?J. Child Psychol. Psychiatry17, 35β5610.1111/j.1469-7610.1976.tb00372.x1249139 | β | β | β |
| SchlaggarB. L.BrownT. T.LugarH. M.VisscherK. M.MiezinF. M.PetersenS. E. (2002). Functional neuroanatomical differences between adults and school-age children in the processing of single words. Science296, 1476β147910.1126/science.106946412029136 | β | β | β |
| SchultzW. (1998). Predictive reward signal of dopamine neurons. J. Neurophysiol.80, 1β27965802510.1152/jn.1998.80.1.1 | β | β | β |
| SeemanP.BzowejN. H.GuanH.-C.BergeronC.BeckerL. E.ReynoldsG. P.BirdE. D.RiedererP.JellingerK.WatanabeS.TourtellotteW. W. (1987). Human brain dopamine receptors in children and aging adults. Synapse1, 399β40410.1002/syn.8900105033505371 | β | β | β |
| ShawP.KabaniN. J.LerchJ. P.EckstrandK.LenrootR.GogtayN.GreensteinD.ClasenL.EvansA.RapoportJ. L.GieddJ. N.WiseS. P. (2008). Neurodevelopmental trajectories of the human cerebral cortex. J. Neurosci.28, 3586β359410.1523/JNEUROSCI.5309-07.200818385317PMC6671079 | β | β | β |
| SomervilleL. H.JonesR. M.CaseyB. J. (2009). A time of change: Behavioral and neural correlates of adolescent sensitivity to appetitive and aversive environmental cues. Brain Cogn. [Epub ahead of print].10.1016/j.bandc.2009.07.003PMC281493619695759 | β | β | β |
| SowellE. R.PetersonB. S.ThompsonP. M.WelcomeS. E.HenkeniusA. L.TogaA. W. (2003). Mapping cortical change across the human life span. Nat. Neurosci.6, 309β31510.1038/nn100812548289 | β | β | β |
| SowellE. R.ThompsonP. M.HolmesC. J.JerniganT. L.TogaA. W. (1999). In vivo evidence for post-adolescent brain maturation in frontal and striatal regions. Nat. Neurosci.2, 859β86110.1038/1315410491602 | β | β | β |
| SpearL. P. (2000). The adolescent brain and age-related behavioral manifestations. Neurosci. Biobehav. Rev.24, 417β46310.1016/S0149-7634(00)00014-210817843 | β | β | β |
| StamfordJ. A. (1989). Development and ageing of the rat nigrostriatal dopamine system studied with fast cyclic voltammetry. J. Neurochem.52, 1582β158910.1111/j.1471-4159.1989.tb09212.x2709014 | β | β | β |
| SteinbergL. (2004). Risk taking in adolescence: what changes, and why?Ann. N. Y. Acad. Sci.1021, 51β5810.1196/annals.1308.00515251873 | β | β | β |
| SteinbergL. (2005). A social neuroscience perspective on adolescent risk-taking. Dev. Rev.28, 78β10610.1016/j.dr.2007.08.00218509515PMC2396566 | β | β | β |
| SteinbergL. (2008). A social neuroscience perspective on adolescent risk- taking. Dev. Rev 28, 78β10610.1016/j.dr.2007.08.00218509515PMC2396566 | β | β | β |
| TaraziF. I.TomasiniE. C.BaldessariniR. J. (1998). Postnatal development of dopamine D4-like receptors in rat forebrain regions: comparison with D2-like receptors. Dev. Brain Res.110, 227β23310.1016/S0165-3806(98)00111-49748595 | β | β | β |
| TaraziF. I.TomasiniE. C.BaldessariniR. J. (1999). Postnatal development of dopamine D1-like receptors in rat cortical and striatolimbic brain regions: an autoradiographic study. Dev. Neurosci.21, 43β4910.1159/00001736510077701 | β | β | β |
| TeicherM. H.AndersenS. L.HostetterJ. C.Jr. (1995). Evidence for dopamine receptor pruning between adolescence and adulthood in striatum but not nucleus accumbens. Dev. Brain Res.89, 167β17210.1016/0165-3806(95)00109-Q8612321 | β | β | β |
| TeicherM. H.BarberN. I.GelbardH. A.GallitanoA. L.CampbellAMarshEBaldessariniR. J. (1993). Developmental differences in acute nigrostriatal and mesocorticolimbic system response to haloperidol. Neuropsychopharmacology9, 147β156821669710.1038/npp.1993.53 | β | β | β |
| ThomasonM. E.BurrowsB. E.GabrieliJ. D. E.GloverG. H. (2005). Breath holding reveals differences in fMRI BOLD signal in children, and adults. Neuroimage25, 824β83710.1016/j.neuroimage.2004.12.02615808983 | β | β | β |
| TomS. M.FoxC. R.TrepelC.PoldrackR. A. (2007). The neural basis of loss aversion in decision-making under risk. Science315, 515β51810.1126/science.113423917255512 | β | β | β |
| van de MoorteleP. F.PfeufferJ.GloverG. H.UgurbilK.HuX. (2002). Respiration-induced B0 fluctuations and their spatial distribution in the human brain at 7 Tesla. Magn. Reson. Med.47, 888β89510.1002/mrm.1014511979567 | β | β | β |
| van LeijenhorstL.ZanolieK.van MeelC. S.WestenbergP. MRomboutsS. ACroneE. A. (2009). What motivates the adolescent? Brain regions mediating reward sensitivity across adolescence. Cereb. Cortex [Epub ahead of print].10.1093/cercor/bhp07819406906 | β | β | β |
| WatsonD.ClarkL. (1984). Negative affectivity: the disposition to experience aversive emotional states. Psychol. Bull.96, 465β49010.1037/0033-2909.96.3.4656393179 | β | β | β |
| WillisT. A.VacarroD.McNamaraG. (1994). Novelty seeking, risk taking, and related constructs as predictors of adolescence substance abuse: an application of Cloniger's theory. J. Subst. Abuse6, 1β2010.1016/S0899-3289(94)90039-68081104 | β | β | β |
In this knowledge base
External
| Title | Authors | Journal | Year | Link |
|---|---|---|---|---|
| A Digital Tool for Assessing the Distinct Effects of Depression, Anxiety, and Attention-Deficit/Hyperactivity Disorder (ADHD) on Children's Emotional Cognitive Bias: Cross-Sectional Study. | Park SE et al. | β | 2026 | β |
| Consummatory deficits in close social reward predict inflammation-induced depressed mood. | Boyle CC et al. | β | 2026 | β |
| Developmental differences in reward-learning and its connection to resting-state functional connectivity modeled using a hierarchical Bayesian model. | Karlocai Z et al. | β | 2026 | β |
| Driven by motivation, fueled by rage, and struggling to disengage: a serial mediation model of internet gaming disorder in adolescents. | MichaΕkiewicz N et al. | β | 2026 | β |
| Engagement, preference and identity: Proposing a developmental engagement framework. | Son M et al. | β | 2026 | β |
| Interaction Effects of Irritability and Anhedonia on ERP and Time-Frequency Measures of Reward Sensitivity. | Bellaert N et al. | β | 2026 | β |
| Naloxone and Buprenorphine Treatment for Adolescent Opioid Overdose and Opioid Use Disorder: A Review. | Ball A et al. | β | 2026 | β |
| Neural response to reward uncertainty in adolescents with mood and anxiety symptoms. | Liu Q et al. | β | 2026 | β |
| Psychotic-like experiences in adolescents enriched for high-risk for developing severe mental illness: change over two-years and associations with neural reward processing and affective symptoms. | Dong X et al. | β | 2026 | β |
| Adolescent mice exhibit lower reward sensitivity than adults. | MisioΕek K et al. | β | 2025 | β |
| A multimethod examination of impulsivity and its association with gamma-aminobutyric acid (GABA), glutamate, and other neurometabolite levels in youth who do and do not use alcohol. | Porter AM et al. | β | 2025 | β |
| Childhood anhedonia symptoms and stressful life events predict the development of reward-related brain activity across adolescence. | Szenczy AK et al. | β | 2025 | β |
| Compensatory Mechanisms in Prefrontal and Reward Systems Reveal Delayed Brain Aging in Musicians. | Ma R et al. | β | 2025 | β |
| Development of Self-Reported Reward Responsiveness and Inhibitory Control and the Role of Clinical and Neural Predictors. | Mattoni M et al. | β | 2025 | β |
| Dynamic Functional Connectivity Between Amygdala and Cognitive Control Network Predicts Delay Discounting in Older Adolescents. | Mertens AT et al. | β | 2025 | β |
| Emotion Regulation and Neural Connectivity After Frustrative Non-Reward in Adolescents: The Moderating Role of Cognitive Flexibility. | Yuan Y et al. | β | 2025 | β |
| Fractionating impulsivity and reward-related phenotypes in adolescent mice. | Albert-Lyons R et al. | β | 2025 | β |
| Functional connectivity between the nucleus accumbens and amygdala underlies avoidance learning during adolescence: Implications for developmental psychopathology. | Rosenberg BM et al. | β | 2025 | β |
| How Familiarity, Musical Affinity, and ADHD Shape Adolescents' Perception of Musical Emotions. | Robaczewski A et al. | β | 2025 | β |
| Human amygdala nuclei show distinct developmental trajectories from adolescence to adulthood in functional integration with prefrontal circuitry. | Ojha A et al. | β | 2025 | β |
| Modelling Incentive Salience in Adolescent Substance Use: The Influence of Substance Cues, Alcohol Expectancies and Socio-Environmental Factors. | Gunawan T et al. | β | 2025 | β |
| Nucleus Accumbens Resting State Functional Connectivity is Linked to Family Income, Reward Salience, and Substance Use. | Assari S et al. | β | 2025 | β |
| Potential roles for microglia in drug addiction: Adolescent neurodevelopment and beyond. | Martinez MX et al. | β | 2025 | β |
| Readdressing the Ongoing Challenge of Missing Data in Youth Ecological Momentary Assessment Studies: Meta-Analysis Update. | Drexl K et al. | β | 2025 | β |
| Reward-seeking behaviors moderate the association between early life adversity and anhedonia 12β―months later. | Tran ML et al. | β | 2025 | β |
| Sex- and reward-dependent effects of early life scarcity-adversity on adolescent behavioral responses to natural rewards. | Salazar MG et al. | β | 2025 | β |
| Sex differences in maturational timing of amygdala and prefrontal cortex volumes and white matter tract microstructure. | Roeske J et al. | β | 2025 | β |
| Temporal Predictions from Anhedonia To Anxiety in Adolescents with Major Depressive Disorder. | Lee YD et al. | β | 2025 | β |
| The connecting brain in context: How adolescent plasticity supports learning and development. | Baker AE et al. | β | 2025 | β |
| The consequences of ultra-processed foods on brain development during prenatal, adolescent and adult stages. | Mottis G et al. | β | 2025 | β |
| Twice as nice: Boosts in adolescent reinforcement learning from Pavlovian bias and age-related prioritization of reward-motivated incidental memory | Hegefeld H et al. | β | 2025 | β |
| Within-person imbalance of reward sensitivity and executive functioning across adolescent development: A longitudinal examination of the dual systems model from childhood to adulthood. | Lozano Wun V et al. | β | 2025 | β |
| A critical review of hot executive functioning in youth attention-deficit/hyperactivity disorder: Methodological limitations, conceptual considerations, and future directions. | Smith JN et al. | β | 2024 | β |
| A unique multi-synaptic mechanism involving acetylcholine and GABA regulates dopamine release in the nucleus accumbens through early adolescence in male rats. | Iacino MC et al. | β | 2024 | β |
| Development of the triadic neural systems involved in risky decision-making during childhood. | Jiang M et al. | β | 2024 | β |
| Distinct Topological Properties of the Reward Anticipation Network in Preadolescent Children With Binge Eating Disorder Symptoms. | Martin E et al. | β | 2024 | β |
| Increased ventral anterior insular connectivity to sports betting availability indexes problem gambling. | Brevers D et al. | β | 2024 | β |
| Neuroscience-informed classification of prevention interventions in substance use disorders: An RDoC-based approach. | Rezapour T et al. | β | 2024 | β |
| Predictions about reward outcomes in rhesus monkeys. | Huang Y et al. | β | 2024 | β |
| Prospective Association Between Tobacco Use and at-Risk Alcohol Consumption Among Swedish Adolescents: Outlining the Influence of Tobacco Product, Frequency of Use and Gender in the LoRDIA Cohort. | Andersson J et al. | β | 2024 | β |
| Sex-Specific Impacts of Early Life Sleep Disruption: Ethanol Seeking, Social Interaction, and Anxiety Are Differentially Altered in Adolescent Prairie Voles. | Ginder DE et al. | β | 2024 | β |
| Striatal and Behavioral Responses to Reward Vary by Socioeconomic Status in Adolescents. | Decker AL et al. | β | 2024 | β |
| Using hierarchical drift diffusion models to elucidate computational mechanisms of reduced reward sensitivity in adolescent major depressive disorder. | Shen L et al. | β | 2024 | β |
| Action initiation and punishment learning differ from childhood to adolescence while reward learning remains stable. | Pauli R et al. | β | 2023 | β |
| Brain Networks and Adolescent Alcohol Use. | Yip SW et al. | β | 2023 | β |
| Development and validation of an fMRI-informed EEG model of reward-related ventral striatum activation. | Singer N et al. | β | 2023 | β |
| Emergence of the Metaverse and Psychiatric Concerns in Children and Adolescents. | Kim S et al. | β | 2023 | β |
| Examining Blunted Initial Response to Reward and Recent Suicidal Ideation in Children and Adolescents Using Event-Related Potentials: Failure to Conceptually Replicate Across Two Independent Samples. | Gallyer AJ et al. | β | 2023 | β |
| Exogenous testosterone administration is associated with differential neural response to unfamiliar peer's and own caregiver's voice in transgender adolescents. | Morningstar M et al. | β | 2023 | β |
| Exploring global trends and future directions in advertising research: A focus on consumer behavior. | Alsharif AH et al. | β | 2023 | β |
| Heightened adolescent emotional reactivity in the brain is associated with lower future distress tolerance and higher depressive symptoms. | Del Giacco AC et al. | β | 2023 | β |
| mHealth Apps Targeting Obesity and Overweight in Young People: App Review and Analysis. | Vlahu-Gjorgievska E et al. | β | 2023 | β |
| Mood Symptom Dimensions and Developmental Differences in Neurocognition in Adolescence. | Kaiser RH et al. | β | 2023 | β |
| Neural activation to peer acceptance and rejection in relation to concurrent and prospective depression risk in adolescent and pre-adolescent girls. | Stroud LR et al. | β | 2023 | β |
| Old enough to offend but not to buy a hamster: the argument for raising the minimum age of criminal responsibility. | Singh Y | β | 2023 | β |
| Possible role of caffeine in nicotine use onset among early adolescents: Evidence from the Young Mountaineer Health Study Cohort. | Kristjansson AL et al. | β | 2023 | β |
| Reappraising the role of dopamine in adolescent risk-taking behavior. | FranΓ§a TFA et al. | β | 2023 | β |
| Social threat, fronto-cingulate-limbic morphometry, and symptom course in depressed adolescents: a longitudinal investigation. | Ojha A et al. | β | 2023 | β |
| Splitting the reward: Differences in inflammatory marker associations with neural connectivity between reward anticipation and reward outcome in adolescents at high risk for depression. | Rengasamy M et al. | β | 2023 | β |
| Subgenual Anterior Cingulate Cortex Reactivity to Rejection Vs. Acceptance Predicts Depressive Symptoms among Adolescents with an Anxiety History. | Silk JS et al. | β | 2023 | β |
| The contribution of theta and delta to feedback processing in children with developmental language disorder. | Gul A et al. | β | 2023 | β |
| The Effects of Digital Addiction on Brain Function and Structure of Children and Adolescents: A Scoping Review. | Ding K et al. | β | 2023 | β |
| Thumbs up or thumbs down: neural processing of social feedback and links to social motivation in adolescent girls. | Davis MM et al. | β | 2023 | β |
| A brief child-friendly reward task reliably activates the ventral striatum in two samples of socioeconomically diverse youth. | Peckins MK et al. | β | 2022 | β |
| Adolescent brain maturation and the neuropathological effects of binge drinking: A critical review. | Tetteh-Quarshie S et al. | β | 2022 | β |
| Adolescent novelty seeking is associated with greater ventral striatal and prefrontal brain response during evaluation of risk and reward. | Del Giacco AC et al. | β | 2022 | β |
| Anhedonia and Suicide. | Auerbach RP et al. | β | 2022 | β |
| Characterization of the Core Determinants of Social Influence From a Computational and Cognitive Perspective. | Lee H et al. | β | 2022 | β |
| Computational modeling reveals strategic and developmental differences in the behavioral impact of reward across adolescence. | Fosco WD et al. | β | 2022 | β |
| Consumer Behaviour to Be Considered in Advertising: A Systematic Analysis and Future Agenda. | Alsharif AH et al. | β | 2022 | β |
| Daily prosocial actions during the COVID-19 pandemic contribute to giving behavior in adolescence. | Sweijen SW et al. | β | 2022 | β |
| Gender Differences for Health Indicators in a Sample of School Dropout Adolescents: A Pilot Study. | Mastorci F et al. | β | 2022 | β |
| Greater Cumulative Lifetime Stressor Exposure Predicts Blunted Reward Positivity in Adolescent Girls Followed for 2 Years. | Burani K et al. | β | 2022 | β |
| Individual differences in threat and reward neural circuitry activation: Testing dimensional models of early adversity, anxiety and depression. | Young KS et al. | β | 2022 | β |
| Meaningful engagement: A crossfunctional framework for digital therapeutics. | Strauss G et al. | β | 2022 | β |
| Mesolimbic Neurobehavioral Mechanisms of Reward Motivation in Anorexia Nervosa: A Multimodal Imaging Study. | Tadayonnejad R et al. | β | 2022 | β |
| Mutation of the Ξ±5 nicotinic acetylcholine receptor subunit increases ethanol and nicotine consumption in adolescence and impacts adult drug consumption. | Quijano CardΓ© NA et al. | β | 2022 | β |
| Neural correlates of attachment in adolescents with trauma: a preliminary study on frustrative non-reward. | Yan M et al. | β | 2022 | β |
| Neural heterogeneity underlying late adolescent motivational processing is linked to individual differences in behavioral sensation seeking. | Demidenko MI et al. | β | 2022 | β |
| Neural responses to reward anticipation and feedback in adult and adolescent cannabis users and controls. | Skumlien M et al. | β | 2022 | β |
| Peer presence increases the prosocial behavior of adolescents by speeding the evaluation of outcomes for others. | Sullivan NJ et al. | β | 2022 | β |
| Preventing Substance Abuse in Adolescents: A Review of High-Impact Strategies. | Hsiung H et al. | β | 2022 | β |
| Psychometric properties of the Dimensional Anhedonia Rating Scale in Chinese typical, subthreshold, and clinically depressed adolescents. | Xiao WY et al. | β | 2022 | β |
| Responsivity of the Striatal Dopamine System to Methylphenidate-A Within-Subject I-123-Ξ²-CIT-SPECT Study in Male Children and Adolescents With Attention-Deficit/Hyperactivity Disorder. | Aster HC et al. | β | 2022 | β |
| Reversing anterior insular cortex neuronal hypoexcitability attenuates compulsive behavior in adolescent rats. | Jadhav KS et al. | β | 2022 | β |
| Social learning across adolescence: A Bayesian neurocognitive perspective. | Hofmans L et al. | β | 2022 | β |
| Adolescent anxiety disorders and the developing brain: comparing neuroimaging findings in adolescents and adults. | Xie S et al. | β | 2021 | β |
| Adolescent Brain Development and Contextual Influences: A Decade in Review. | GalvΓ‘n A | β | 2021 | β |
| Age-varying Bi-directional Associations Between Momentary Affect and Movement Behaviors in Children: Evidence From a Multi-wave Ecological Momentary Assessment Study. | Yang CH et al. | β | 2021 | β |
| Altered reward responsiveness and depressive symptoms: An examination of social and monetary reward domains and interactions with rejection sensitivity. | Pegg S et al. | β | 2021 | β |
| Decision-making and cognitive control in adolescent suicidal behaviors: a qualitative systematic review of the literature. | Gifuni AJ et al. | β | 2021 | β |
| Effects of a novel mobile health intervention compared to a multi-component behaviour changing program on body mass index, physical capacities and stress parameters in adolescents with obesity: a randomized controlled trial. | Stasinaki A et al. | β | 2021 | β |
| Effects of substance misuse on reward-processing in patients with attention-deficit/hyperactivity disorder. | Paraskevopoulou M et al. | β | 2021 | β |
| Emotion context insensitivity in depression: Toward an integrated and contextualized approach. | Bylsma LM | β | 2021 | β |
| Factors modulating the incubation of drug and non-drug craving and their clinical implications. | Venniro M et al. | β | 2021 | β |
| Heightened sensitivity to the caregiving environment during adolescence: implications for recovery following early-life adversity. | Colich NL et al. | β | 2021 | β |
| Increased self-reported reward responsiveness predicts better response to cognitive behavioral therapy for youth with anxiety. | Norris LA et al. | β | 2021 | β |
| Individual associations of adolescent alcohol use disorder versus cannabis use disorder symptoms in neural prediction error signaling and the response to novelty. | Aloi J et al. | β | 2021 | β |
| Irregular sleep habits, regional grey matter volumes, and psychological functioning in adolescents. | Lapidaire W et al. | β | 2021 | β |
| Like me Back: Neural Correlates of Low Perceived Relational Value in Peer Victimized Youth. | Fowler CH et al. | β | 2021 | β |
| Mood and emotional reactivity of adolescents during the COVID-19 pandemic: short-term and long-term effects and the impact of social and socioeconomic stressors. | Green KH et al. | β | 2021 | β |
| Reliability of reward- and error-related brain activity in early childhood. | Szenczy AK et al. | β | 2021 | β |
| Social experience calibrates neural sensitivity to social feedback during adolescence: A functional connectivity approach. | Rudolph KD et al. | β | 2021 | β |
| The Developing Brain in the Digital Era: A Scoping Review of Structural and Functional Correlates of Screen Time in Adolescence. | Marciano L et al. | β | 2021 | β |
| The longitudinal stability of fMRI activation during reward processing in adolescents and young adults. | Baranger DAA et al. | β | 2021 | β |
| Adolescence versus adulthood: Differences in basal mesolimbic and nigrostriatal dopamine transmission and response to drugs of abuse. | Corongiu S et al. | β | 2020 | β |
| Adolescent Brain Development and Progressive Legal Responsibility in the Latin American Context. | Mercurio E et al. | β | 2020 | β |
| Adolescent Decision-Making Under Risk: Neural Correlates and Sex Differences. | Korucuoglu O et al. | β | 2020 | β |
| Alcohol Use Disorder, But Not Cannabis Use Disorder, Symptomatology in Adolescents Is Associated With Reduced Differential Responsiveness to Reward Versus Punishment Feedback During Instrumental Learning. | Aloi J et al. | β | 2020 | β |
| Comparing dopamine release, uptake, and D2 autoreceptor function across the ventromedial to dorsolateral striatum in adolescent and adult male and female rats. | Pitts EG et al. | β | 2020 | β |
| Cortical and subcortical response to the anticipation of reward in high and average/low risk-taking adolescents. | Demidenko MI et al. | β | 2020 | β |
| Developmental trajectories to reduced activation of positive valence systems: A review of biological and environmental contributions. | Kujawa A et al. | β | 2020 | β |
| Differential Behavioral and Neural Profiles in Youth With Conduct Problems During Risky Decision-Making. | van Hoorn J et al. | β | 2020 | β |
| Does Alcohol Initiation in Early-To-Middle Adolescence Predict Changes in Reward Motivation? Evidence of Sex Differences. | Mauro KL et al. | β | 2020 | β |
| Effects of Maternal Depression and Mother-Child Relationship Quality in Early Childhood on Neural Reactivity to Rejection and Peer Stress in Adolescence: A 9-Year Longitudinal Study. | Kujawa A et al. | β | 2020 | β |
| Health-Related Behaviors in Adolescents Mediate the Association between Subjective Social Status and Body Mass Index. | Bjertnaes AA et al. | β | 2020 | β |
| Neural Dynamic Responses of Monetary and Social Reward Processes in Adolescents. | Wang D et al. | β | 2020 | β |
| Neural response to rewards predicts risk-taking in late but not early adolescent females. | Freeman C et al. | β | 2020 | β |
| Psychological impacts of "screen time" and "green time" for children and adolescents: A systematic scoping review. | Oswald TK et al. | β | 2020 | β |
| Pubertal testosterone correlates with adolescent impatience and dorsal striatal activity. | Laube C et al. | β | 2020 | β |
| Relationship between Sucrose Taste Detection Thresholds and Preferences in Children, Adolescents, and Adults. | Petty S et al. | β | 2020 | β |
| Reward-Processing Behavior in Depressed Participants Relative to Healthy Volunteers: A Systematic Review and Meta-analysis. | Halahakoon DC et al. | β | 2020 | β |
| The effect of social feedback from peers on adolescent cognitive control. | Hollarek M et al. | β | 2020 | β |
| The perils of murky emotions: Emotion differentiation moderates the prospective relationship between naturalistic stress exposure and adolescent depression. | Starr LR et al. | β | 2020 | β |
| The rational use of causal inference to guide reinforcement learning strengthens with age. | Cohen AO et al. | β | 2020 | β |
| Threat or thrill? the neural mechanisms underlying the development of anxiety and risk taking in adolescence. | Baker AE et al. | β | 2020 | β |
| Valuation of peers' safe choices is associated with substance-naΓ―vetΓ© in adolescents. | Chung D et al. | β | 2020 | β |
| Adolescent Health Risk Behaviors: Convergent, Discriminant and Predictive Validity of Self-Report and Cognitive Measures. | Demidenko MI et al. | β | 2019 | β |
| Adolescents' pubertal development: Links between testosterone, estradiol, and neural reward processing. | Poon JA et al. | β | 2019 | β |
| Adolescents' Reward-related Neural Activation: Links to Thoughts of Nonsuicidal Self-Injury. | Poon JA et al. | β | 2019 | β |
| Age and Gender Effects in Sensitivity to Social Rewards in Adolescents and Young Adults. | AltikulaΓ§ S et al. | β | 2019 | β |
| Anxiety in transition: Neuroendocrine mechanisms supporting the development of anxiety pathology in adolescence and young adulthood. | Spielberg JM et al. | β | 2019 | β |
| Apples to apples? Neural correlates of emotion regulation differences between high- and low-risk adolescents. | Perino MT et al. | β | 2019 | β |
| Differential dysfunctions related to alcohol and cannabis use disorder symptoms in reward and error-processing neuro-circuitries in adolescents. | Aloi J et al. | β | 2019 | β |
| Effect of enriched environment during adolescence on spatial learning and memory, and voluntary consumption of morphine in maternally separated rats in adulthood. | Mohammadian J et al. | β | 2019 | β |
| Fos activation patterns related to acute ethanol and conditioned taste aversion in adolescent and adult rats. | Saalfield J et al. | β | 2019 | β |
| I Knew You Weren't Going to Like Me! Neural Response to Accurately Predicting Rejection Is Associated With Anxiety and Depression. | Quarmley ME et al. | β | 2019 | β |
| Incorporating the social context into neurocognitive models of adolescent decision-making: A neuroimaging meta-analysis. | van Hoorn J et al. | β | 2019 | β |
| Learning with individual-interest outcomes in Autism Spectrum Disorder. | Schuetze M et al. | β | 2019 | β |
| Longitudinal changes in brain structures related to appetitive reactivity and regulation across development. | Martin RE et al. | β | 2019 | β |
| Longitudinal increases in reward-related neural activity in early adolescence: Evidence from event-related potentials (ERPs). | Burani K et al. | β | 2019 | β |
| Neural Activation to Parental Praise Interacts With Social Context to Predict Adolescent Depressive Symptoms. | Sequeira SL et al. | β | 2019 | β |
| Neurobiological responses in the adolescent striatum to being 'tested'. | DePasque S et al. | β | 2019 | β |
| Prenatal drug exposure from infancy through emerging adulthood: Results from neuroimaging. | Morie KP et al. | β | 2019 | β |
| Reduced Reward Responsiveness Predicts Change in Depressive Symptoms in Anxious Children and Adolescents Following Treatment. | Kujawa A et al. | β | 2019 | β |
| Reward processing and future life stress: Stress generation pathway to depression. | Mackin DM et al. | β | 2019 | β |
| Reward Processing in Adolescent Depression Across Neuroimaging Modalities. | O'Callaghan G et al. | β | 2019 | β |
| Rewards Enhance Proactive and Reactive Control in Adolescence and Adulthood. | Magis-Weinberg L et al. | β | 2019 | β |
| Sex Differences in Adolescent Anorexia and Bulimia Nervosa: Beyond the Signs and Symptoms. | Timko CA et al. | β | 2019 | β |
| Sketching the Power of Machine Learning to Decrypt a Neural Systems Model of Behavior. | Ernst M et al. | β | 2019 | β |
| Social and Non-social Reward: A Preliminary Examination of Clinical Improvement and Neural Reactivity in Adolescents Treated With Behavioral Therapy for Anxiety and Depression. | Schwartz KTG et al. | β | 2019 | β |
| Towards robust biomarkers of psychosocial interventions. | Micali N et al. | β | 2019 | β |
| Worth working for: The influence of effort costs on teens' choices during a novel decision making game. | Sullivan-Toole H et al. | β | 2019 | β |
| A Computational Account of Optimizing Social Predictions Reveals That Adolescents Are Conservative Learners in Social Contexts. | Rosenblau G et al. | β | 2018 | β |
| Adolescence as a neurobiological critical period for the development of higher-order cognition. | Larsen B et al. | β | 2018 | β |
| Age and impulsive behavior in drug addiction: A review of past research and future directions. | Argyriou E et al. | β | 2018 | β |
| Age sensitive associations of adolescent substance use with amygdalar, ventral striatum, and frontal volumes in young adulthood. | Windle M et al. | β | 2018 | β |
| A longitudinal examination of event-related potentials sensitive to monetary reward and loss feedback from late childhood to middle adolescence. | Kujawa A et al. | β | 2018 | β |
| Application of Research Domain Criteria to childhood and adolescent impulsive and addictive disorders: Implications for treatment. | Yip SW et al. | β | 2018 | β |
| Asymmetric neural tracking of gain and loss magnitude during adolescence. | Insel C et al. | β | 2018 | β |
| Boys with conduct problems and callous-unemotional traits: Neural response to reward and punishment and associations with treatment response. | Byrd AL et al. | β | 2018 | β |
| Contributions of Reward Sensitivity to Ventral Striatum Activity Across Adolescence and Early Adulthood. | Schreuders E et al. | β | 2018 | β |
| Does early exposure to caffeine promote smoking and alcohol use behavior? A prospective analysis of middle school students. | Kristjansson AL et al. | β | 2018 | β |
| Is the encoding of Reward Prediction Error reliable during development? | Keren H et al. | β | 2018 | β |
| Methodological considerations for developmental longitudinal fMRI research. | Telzer EH et al. | β | 2018 | β |
| Not just social sensitivity: Adolescent neural suppression of social feedback during risk taking. | McCormick EM et al. | β | 2018 | β |
| Novel insights from the Yellow Light Game: Safe and risky decisions differentially impact adolescent outcome-related brain function. | Op de Macks ZA et al. | β | 2018 | β |
| Puberty and the human brain: Insights into adolescent development. | Vijayakumar N et al. | β | 2018 | β |
| Time-frequency approaches to investigating changes in feedback processing during childhood and adolescence. | Bowers ME et al. | β | 2018 | β |
| Assessment of the acquisition of executive function during the transition from adolescence to adulthood in male and female mice. | Shepard R et al. | β | 2017 | β |
| Beyond dual systems: A genetically-informed, latent factor model of behavioral and self-report measures related to adolescent risk-taking. | Harden KP et al. | β | 2017 | β |
| Boys vs. girls: Gender differences in the neural development of trust and reciprocity depend on social context. | Lemmers-Jansen ILJ et al. | β | 2017 | β |
| Development of Monetary and Social Reward Processes. | Wang D et al. | β | 2017 | β |
| Engaging Adolescents to Inform the Development of a Mobile Gaming App to Incentivize Physical Activity. | Pope L et al. | β | 2017 | β |
| Flexing dual-systems models: How variable cognitive control in children informs our understanding of risk-taking across development. | Li R | β | 2017 | β |
| Hanging Out With the Right Crowd: Peer Influence on Risk-Taking Behavior in Adolescence. | Van Hoorn J et al. | β | 2017 | β |
| Illness-Specific Risk-Taking in Adolescence: A Missing Piece of the Nonadherence Puzzle for Youth With Type 1 Diabetes? | Wasserman R et al. | β | 2017 | β |
| Impact of juvenile chronic stress on adult cortico-accumbal function: Implications for cognition and addiction. | Watt MJ et al. | β | 2017 | β |
| Insensitivity to response-contingent feedback in adolescents with developmental language disorder (DLD). | Lee JC | β | 2017 | β |
| Minimizing noise in pediatric task-based functional MRI; Adolescents with developmental disabilities and typical development. | Fassbender C et al. | β | 2017 | β |
| Modulation of reward-related neural activation on sensation seeking across development. | Hawes SW et al. | β | 2017 | β |
| Neural responses to social and monetary reward in early adolescence and emerging adulthood. | Ethridge P et al. | β | 2017 | β |
| Neurobiology of substance use in adolescents and potential therapeutic effects of exercise for prevention and treatment of substance use disorders. | Nock NL et al. | β | 2017 | β |
| Neurodevelopmental Changes in Social Reinforcement Processing: A Functional Magnetic Resonance Imaging Study. | Hwang S et al. | β | 2017 | β |
| Perceived stress and poly-tobacco product use across adolescence: Patterns of association and gender differences. | Leventhal AM et al. | β | 2017 | β |
| Remodeling of Sensorimotor Brain Connectivity in Gpr88-Deficient Mice. | Arefin TM et al. | β | 2017 | β |
| Reprint of: Minimizing noise in pediatric task-based functional MRI; Adolescents with developmental disabilities and typical development. | Fassbender C et al. | β | 2017 | β |
| Sensitive periods of substance abuse: Early risk for the transition to dependence. | Jordan CJ et al. | β | 2017 | β |
| Striatum on the anxiety map: Small detours into adolescence. | Lago T et al. | β | 2017 | β |
| Traumatic brain injuries during development disrupt dopaminergic signaling. | Karelina K et al. | β | 2017 | β |
| Trial-by-Trial Modulation of Associative Memory Formation by Reward Prediction Error and Reward Anticipation as Revealed by a Biologically Plausible Computational Model. | Aberg KC et al. | β | 2017 | β |
| White-matter crossing-fiber microstructure in adolescents prenatally exposed to cocaine. | Morie KP et al. | β | 2017 | β |
| Adolescent behavioral and neural reward sensitivity: a test of the differential susceptibility theory. | Richards JS et al. | β | 2016 | β |
| Developmental changes in electroencephalographic frontal asymmetry in young children at risk for depression. | Goldstein BL et al. | β | 2016 | β |
| Drinking Over the Lifespan: Focus on Early Adolescents and Youth. | Windle M | β | 2016 | β |
| Effects of early life stress on amygdala and striatal development. | Fareri DS et al. | β | 2016 | β |
| Olanzapine Treatment of Adolescent Rats Alters Adult D2 Modulation of Cortical Inputs to the Ventral Striatum. | Brooks JM et al. | β | 2016 | β |
| Revising the BIS/BAS Scale to study development: Measurement invariance and normative effects of age and sex from childhood through adulthood. | Pagliaccio D et al. | β | 2016 | β |
| Reward Processing and Risk for Depression Across Development. | Luking KR et al. | β | 2016 | β |
| Sensation seeking, peer deviance, and genetic influences on adolescent delinquency: Evidence for person-environment correlation and interaction. | Mann FD et al. | β | 2016 | β |
| Social re-orientation and brain development: An expanded and updated view. | Nelson EE et al. | β | 2016 | β |
| The dual systems model: Review, reappraisal, and reaffirmation. | Shulman EP et al. | β | 2016 | β |
| The impact of therapists' words on the adolescent brain: In the context of addiction treatment. | Feldstein Ewing SW et al. | β | 2016 | β |
| Adolescent girls' neural response to reward mediates the relation between childhood financial disadvantage and depression. | Romens SE et al. | β | 2015 | β |
| Anticipation of peer evaluation in anxious adolescents: divergence in neural activation and maturation. | Spielberg JM et al. | β | 2015 | β |
| A Two-Hit Model of Autism: Adolescence as the Second Hit. | Picci G et al. | β | 2015 | β |
| Biological Risk for the Development of Problem Behavior in Adolescence: Integrating Insights from Behavioral Genetics and Neuroscience. | Harden KP et al. | β | 2015 | β |
| Child Gain Approach and Loss Avoidance Behavior: Relationships With Depression Risk, Negative Mood, andΒ Anhedonia. | Luking KR et al. | β | 2015 | β |
| Cognitive flexibility in adolescence: neural and behavioral mechanisms of reward prediction error processing in adaptive decision making during development. | Hauser TU et al. | β | 2015 | β |
| Does incentive-elicited nucleus accumbens activation differ by substance of abuse? An examination with adolescents. | Karoly HC et al. | β | 2015 | β |
| Effects of anabolic-androgens on brain reward function. | Mhillaj E et al. | β | 2015 | β |
| Family history density of alcoholism relates to left nucleus accumbens volume in adolescent girls. | Cservenka A et al. | β | 2015 | β |
| Increased brain response to appetitive tastes in the insula and amygdala in obese compared with healthy weight children when sated. | Boutelle KN et al. | β | 2015 | β |
| Increased neural responses to reward in adolescents and young adults with attention-deficit/hyperactivity disorder and their unaffected siblings. | von Rhein D et al. | β | 2015 | β |
| Learning to play it safe (or not): stable and evolving neural responses during adolescent risky decision-making. | Kahn LE et al. | β | 2015 | β |
| Neural correlates of expected risks and returns in risky choice across development. | van Duijvenvoorde AC et al. | β | 2015 | β |
| Neural networks involved in adolescent reward processing: An activation likelihood estimation meta-analysis of functional neuroimaging studies. | Silverman MH et al. | β | 2015 | β |
| Neuroeconomics for the study of social cognition in adolescent depression. | Mellick W et al. | β | 2015 | β |
| Normative development of ventral striatal resting state connectivity in humans. | Fareri DS et al. | β | 2015 | β |
| Reduced cerebellar brain activity during reward processing in adolescent binge drinkers. | Cservenka A et al. | β | 2015 | β |
| The neuroscience of adolescent decision-making. | Hartley CA et al. | β | 2015 | β |
| Adolescent brain maturation and smoking: what we know and where we're headed. | Lydon DM et al. | β | 2014 | β |
| Adolescent pediatric decision-making: a critical reconsideration in the light of the data. | Partridge B | β | 2014 | β |
| Adolescents adapt more slowly than adults to varying reward contingencies. | Javadi AH et al. | β | 2014 | β |
| Age and sex differences in reward behavior in adolescent and adult rats. | Hammerslag LR et al. | β | 2014 | β |
| Anhedonia and depressed mood in adolescence: course, stability, and reciprocal relation in the TRAILS study. | Bennik EC et al. | β | 2014 | β |
| An Overview of Judgment and Decision Making Research Through the Lens of Fuzzy Trace Theory. | Setton R et al. | β | 2014 | β |
| But do you think I'm cool? Developmental differences in striatal recruitment during direct and reflected social self-evaluations. | Jankowski KF et al. | β | 2014 | β |
| Effect of GABRA2 genotype on development of incentive-motivation circuitry in a sample enriched for alcoholism risk. | Heitzeg MM et al. | β | 2014 | β |
| Effects of anonymous peer observation on adolescents' preference for immediate rewards. | Weigard A et al. | β | 2014 | β |
| Exciting fear in adolescence: does pubertal development alter threat processing? | Spielberg JM et al. | β | 2014 | β |
| Exploring the relationship of functional network connectivity to latent trajectories of alcohol use and risky sex. | Thayer RE et al. | β | 2014 | β |
| Feedback processing in adolescence: an event-related potential study of age and gender differences. | Grose-Fifer J et al. | β | 2014 | β |
| Gaining insight into adolescent vulnerability for social anxiety from developmental cognitive neuroscience. | Caouette JD et al. | β | 2014 | β |
| Kids, candy, brain and behavior: age differences in responses to candy gains and losses. | Luking KR et al. | β | 2014 | β |
| Longitudinal study of striatal activation to reward and loss anticipation from mid-adolescence into late adolescence/early adulthood. | Lamm C et al. | β | 2014 | β |
| Neural representation of expected value in the adolescent brain. | Barkley-Levenson E et al. | β | 2014 | β |
| Prenatal cocaine exposure and adolescent neural responses to appetitive and stressful stimuli. | Yip SW et al. | β | 2014 | β |
| Quantifying familial influences on brain activation during the monetary incentive delay task: an adolescent monozygotic twin study. | Silverman MH et al. | β | 2014 | β |
| Relationships between reward sensitivity, risk-taking and family history of alcoholism during an interactive competitive fMRI task. | Yarosh HL et al. | β | 2014 | β |
| Reward anticipation in the adolescent and aging brain. | Lorenz RC et al. | β | 2014 | β |
| Temporal reward discounting in children, adolescents, and emerging adults during an experiential task. | Scheres A et al. | β | 2014 | β |
| Value-driven attentional capture in adolescence. | Roper ZJ et al. | β | 2014 | β |
| Ventral-striatal responsiveness during reward anticipation in ADHD and its relation to trait impulsivity in the healthy population: a meta-analytic review of the fMRI literature. | Plichta MM et al. | β | 2014 | β |
| Where is the "g" in creativity? A specialization-differentiation hypothesis. | Barbot B et al. | β | 2014 | β |
| Adolescent neurodevelopment. | Spear LP | β | 2013 | β |
| Adolescent transformations of behavioral and neural processes as potential targets for prevention. | Eldreth D et al. | β | 2013 | β |
| An FMRI study investigating adolescent brain activation by rewards and feedback. | Choi WH et al. | β | 2013 | β |
| A systematic review of fMRI reward paradigms used in studies of adolescents vs. adults: the impact of task design and implications for understanding neurodevelopment. | Richards JM et al. | β | 2013 | β |
| Bupropion induced changes in exploratory and anxiety-like behaviour in NMRI male mice depends on the age. | Carrasco MC et al. | β | 2013 | β |
| Circadian misalignment, reward-related brain function, and adolescent alcohol involvement. | Hasler BP et al. | β | 2013 | β |
| Cognitive Control and Motivation. | Luna B et al. | β | 2013 | β |
| Different developmental trajectories for anticipation and receipt of reward during adolescence. | Hoogendam JM et al. | β | 2013 | β |
| Gambling proneness in rats during the transition from adolescence to young adulthood: a home-cage method. | Zoratto F et al. | β | 2013 | β |
| Genetic and neurophysiological correlates of the age of onset of alcohol use disorders in adolescents and young adults. | Chorlian DB et al. | β | 2013 | β |
| High and low sensation seeking adolescents show distinct patterns of brain activity during reward processing. | Cservenka A et al. | β | 2013 | β |
| Impact of socio-emotional context, brain development, and pubertal maturation on adolescent risk-taking. | Smith AR et al. | β | 2013 | β |
| Nucleus accumbens, thalamus and insula connectivity during incentive anticipation in typical adults and adolescents. | Cho YT et al. | β | 2013 | β |
| Piece of cake. Cognitive reappraisal of food craving. | Giuliani NR et al. | β | 2013 | β |
| Risk-taking and social exclusion in adolescence: neural mechanisms underlying peer influences on decision-making. | Peake SJ et al. | β | 2013 | β |
| Sex differences during humor appreciation in child-sibling pairs. | Vrticka P et al. | β | 2013 | β |
| The amygdala: an agent of change in adolescent neural networks. | Scherf KS et al. | β | 2013 | β |
| The value of the dual systems model of adolescent risk-taking. | Strang NM et al. | β | 2013 | β |
| Why is adolescence a key period of alcohol initiation and who is prone to develop long-term problem use?: A review of current available data. | Petit G et al. | β | 2013 | β |
| Adolescence as a turning point: for better and worse. | Buitelaar JK | β | 2012 | β |
| Adolescent risk taking under stressed and nonstressed conditions: conservative, calculating, and impulsive types. | Johnson SB et al. | β | 2012 | β |
| An imaging genetics approach to understanding social influence. | Falk EB et al. | β | 2012 | β |
| Arrested development? Reconsidering dual-systems models of brain function in adolescence and disorders. | Pfeifer JH et al. | β | 2012 | β |
| Cognitive set-shifting in anorexia nervosa. | Shott ME et al. | β | 2012 | β |
| Considerations for imaging the adolescent brain. | GalvΓ‘n A et al. | β | 2012 | β |
| Developmental effects of incentives on response inhibition. | Geier CF et al. | β | 2012 | β |
| Differential neurobiological effects of expert advice on risky choice in adolescents and adults. | Engelmann JB et al. | β | 2012 | β |
| Electrophysiological markers of the motivational salience of delay imposition and escape. | Broyd SJ et al. | β | 2012 | β |
| Neural response to reward and depressive symptoms in late childhood to early adolescence. | Bress JN et al. | β | 2012 | β |
| Striatum-medial prefrontal cortex connectivity predicts developmental changes in reinforcement learning. | van den Bos W et al. | β | 2012 | β |
| Understanding adolescence as a period of social-affective engagement and goal flexibility. | Crone EA et al. | β | 2012 | β |
| Weekend-weekday advances in sleep timing are associated with altered reward-related brain function in healthy adolescents. | Hasler BP et al. | β | 2012 | β |
| Where is the pleasure in that? Low hedonic capacity predicts smoking onset and escalation. | Audrain-McGovern J et al. | β | 2012 | β |
| White matter development in adolescence: the influence of puberty and implications for affective disorders. | Ladouceur CD et al. | β | 2012 | β |
| Why do anxious children become depressed teenagers? The role of social evaluative threat and reward processing. | Silk JS et al. | β | 2012 | β |
| Addiction, adolescence, and the integration of control and motivation. | Gladwin TE et al. | β | 2011 | β |
| Developmental changes in brain function underlying the influence of reward processing on inhibitory control. | Padmanabhan A et al. | β | 2011 | β |
| Developmental trajectories during adolescence in males and females: a cross-species understanding of underlying brain changes. | Brenhouse HC et al. | β | 2011 | β |
| Deviant peer affiliation and antisocial behavior: interaction with Monoamine Oxidase A (MAOA) genotype. | Lee SS | β | 2011 | β |
| Individuals family history positive for alcoholism show functional magnetic resonance imaging differences in reward sensitivity that are related to impulsivity factors. | Andrews MM et al. | β | 2011 | β |
| Juvenile mice show greater flexibility in multiple choice reversal learning than adults. | Johnson C et al. | β | 2011 | β |
| Neural correlates of response inhibition and cigarette smoking in late adolescence. | GalvΓ‘n A et al. | β | 2011 | β |
| Neurocognitive development of risk aversion from early childhood to adulthood. | Paulsen DJ et al. | β | 2011 | β |
| Prospective association of childhood attention-deficit/hyperactivity disorder (ADHD) and substance use and abuse/dependence: a meta-analytic review. | Lee SS et al. | β | 2011 | β |
| Reward improves cancellation and restraint inhibition across childhood and adolescence. | Sinopoli KJ et al. | β | 2011 | β |
| Rewards, aversions and affect in adolescence: emerging convergences across laboratory animal and human data. | Spear LP | β | 2011 | β |
| Testosterone levels correspond with increased ventral striatum activation in response to monetary rewards in adolescents. | Op de Macks ZA et al. | β | 2011 | β |
| The development of memory efficiency and value-directed remembering across the life span: a cross-sectional study of memory and selectivity. | Castel AD et al. | β | 2011 | β |
| Adolescent brain development and the risk for alcohol and other drug problems. | Bava S et al. | β | 2010 | β |
| [FranΓ§ois Lepage (1905--1978)]. | Sureau C | β | 1978 | β |