Multipoint quantitative-trait linkage analysis in general pedigrees.
paper
Cited
Public
Unavailable
- Authors
- Almasy, L; Blangero, J
- Year
- 1998
- Journal
- American journal of human genetics
- PMID
- 9545414
- DOI
- 10.1086/301844
- PMCID
- PMC1377101
Multipoint linkage analysis of quantitative-trait loci (QTLs) has previously been restricted to sibships and small pedigrees. In this article, we show how variance-component linkage methods can be used in pedigrees of arbitrary size and complexity, and we develop a general framework for multipoint identity-by-descent (IBD) probability calculations. We extend the sib-pair multipoint mapping approach of Fulker et al. to general relative pairs. This multipoint IBD method uses the proportion of alleles shared identical by descent at genotyped loci to estimate IBD sharing at arbitrary points along a chromosome for each relative pair. We have derived correlations in IBD sharing as a function of chromosomal distance for relative pairs in general pedigrees and provide a simple framework whereby these correlations can be easily obtained for any relative pair related by a single line of descent or by multiple independent lines of descent. Once calculated, the multipoint relative-pair IBDs can be utilized in variance-component linkage analysis, which considers the likelihood of the entire pedigree jointly. Examples are given that use simulated data, demonstrating both the accuracy of QTL localization and the increase in power provided by multipoint analysis with 5-, 10-, and 20-cM marker maps. The general pedigree variance component and IBD estimation methods have been implemented in the SOLAR (Sequential Oligogenic Linkage Analysis Routines) computer package.
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| Heritability of the pharyngeal airway volume and dimensions as assessed from siblings with overt malocclusions. | Al-Qawasmi R et al. | β | 2019 | β |
| Homogenizing Estimates of Heritability Among SOLAR-Eclipse, OpenMx, APACE, and FPHI Software Packages in Neuroimaging Data. | Kochunov P et al. | β | 2019 | β |
| Human Cortical Thickness Organized into Genetically-determined Communities across Spatial Resolutions. | Alexander-Bloch AF et al. | β | 2019 | β |
| Identification of novel sarcoma risk genes using a two-stage genome wide DNA sequencing strategy in cancer cluster families and population case and control cohorts. | Jones RM et al. | β | 2019 | β |
| Influence of <i>ABO</i> Locus on PFA-100 Collagen-ADP Closure Time Is Not Totally Dependent on the Von Willebrand Factor. Results of a GWAS on GAIT-2 Project Phenotypes. | Pujol-Moix N et al. | β | 2019 | β |
| Intrinsic and extrinsic epigenetic age acceleration are associated with hypertensive target organ damage in older African Americans. | Smith JA et al. | β | 2019 | β |
| Network organization of co-opetitive genetic influences on morphologies of the human cerebral cortex. | Paul S et al. | β | 2019 | β |
| Person-Based Brain Morphometric Similarity is Heritable and Correlates With Biological Features. | Doucet GE et al. | β | 2019 | β |
| Plasticity versus stability across the human cortical visual connectome. | Haak KV et al. | β | 2019 | β |
| Protocols, Methods, and Tools for Genome-Wide Association Studies (GWAS) of Dental Traits. | Agler CS et al. | β | 2019 | β |
| Quantitative genetic analyses of postcanine morphological crown variation. | Stojanowski CM et al. | β | 2019 | β |
| Rare <i>DEGS1</i> variant significantly alters de novo ceramide synthesis pathway. | Blackburn NB et al. | β | 2019 | β |
| Statistical power in genome-wide association studies and quantitative trait locus mapping. | Wang M et al. | β | 2019 | β |
| Targeted sequencing of linkage region in Dominican families implicates PRIMA1 and the SPATA7-PTPN21-ZC3H14-EML5-TTC8 locus in carotid-intima media thickness and atherosclerotic events. | Wang L et al. | β | 2019 | β |
| The genetic and environmental etiology of child maltreatment in a parent-based extended family design. | Pittner K et al. | β | 2019 | β |
| The Relationship Between the Uncinate Fasciculus and Anxious Temperament Is Evolutionarily Conserved and Sexually Dimorphic. | Tromp DPM et al. | β | 2019 | β |
| The triglyceride to high-density lipoprotein cholesterol (TG/HDL-C) ratio as a predictor of insulin resistance, Ξ²-cell function, and diabetes in Hispanics and African Americans. | Young KA et al. | β | 2019 | β |
| Two novel homozygous mutations in NPHP1 lead to late onset end-stage renal disease: a case report of an adult nephronophthisis in a Chinese intermarriage family. | Wang Y et al. | β | 2019 | β |
| Variance Components Models for Analysis of Big Family Data of Health Outcomes in the Lifelines Cohort Study. | Demetrashvili N et al. | β | 2019 | β |
| Whole-exome sequencing in multiplex preeclampsia families identifies novel candidate susceptibility genes. | Melton PE et al. | β | 2019 | β |
| Whole genome sequence association with E-selectin levels reveals loss-of-function variant in African Americans. | Polfus LM et al. | β | 2019 | β |
| A Bayesian mixed modeling approach for estimating heritability. | Nustad HE et al. | β | 2018 | β |
| Additive genetic variation in the craniofacial skeleton of baboons (genus Papio) and its relationship to body and cranial size. | Joganic JL et al. | β | 2018 | β |
| Age-associated microRNA expression in human peripheral blood is associated with all-cause mortality and age-related traits. | Huan T et al. | β | 2018 | β |
| Application of novel and existing methods to identify genes with evidence of epigenetic association: results from GAW20. | Fuady AM et al. | β | 2018 | β |
| Arsenic-gene interactions and beta-cell function in the Strong Heart Family Study. | Balakrishnan P et al. | β | 2018 | β |
| A scalable estimator of SNP heritability for biobank-scale data. | Wu Y et al. | β | 2018 | β |
| Assessment of Cognition and Personality as Potential Endophenotypes in the Western Australian Family Study of Schizophrenia. | McCarthy NS et al. | β | 2018 | β |
| Behavioral and EEG responses to social evaluation: A two-generation family study on social anxiety. | Harrewijn A et al. | β | 2018 | β |
| Characterization of the contribution of shared environmental and genetic factors to metabolic syndrome methylation heritability and familial correlations. | FernΓ‘ndez-Rhodes L et al. | β | 2018 | β |
| Cognition and community functioning in schizophrenia: The nature of the relationship. | Kuo SS et al. | β | 2018 | β |
| Comparison of heritability estimates on resting state fMRI connectivity phenotypes using the ENIGMA analysis pipeline. | Adhikari BM et al. | β | 2018 | β |
| Delta-beta correlation as a candidate endophenotype of social anxiety: A two-generation family study. | Harrewijn A et al. | β | 2018 | β |
| Diet-induced early-stage atherosclerosis in baboons: Lipoproteins, atherogenesis, and arterial compliance. | Mahaney MC et al. | β | 2018 | β |
| Disease Heritability Inferred from Familial Relationships Reported in Medical Records. | Polubriaginof FCG et al. | β | 2018 | β |
| Disentangling the genetic overlap between cholesterol and suicide risk. | Knowles EEM et al. | β | 2018 | β |
| DNA sequence-level analyses reveal potential phenotypic modifiers in a large family with psychiatric disorders. | Ryan NM et al. | β | 2018 | β |
| Epigenetics, heritability and longitudinal analysis. | Nustad HE et al. | β | 2018 | β |
| Evaluation of a phenotype imputation approach using GAW20 simulated data. | Chen Y et al. | β | 2018 | β |
| Exome Sequencing Identifies Genetic Variants Associated with Circulating Lipid Levels in Mexican Americans: The Insulin Resistance Atherosclerosis Family Study (IRASFS). | Gao C et al. | β | 2018 | β |
| Familial Aggregation and Heritability of Loa loa Microfilaremia. | Eyebe S et al. | β | 2018 | β |
| Familial clustering of vitamin D deficiency via shared environment: The Korean National Health and Nutrition Examination Survey 2008-2012. | Hong N et al. | β | 2018 | β |
| Fast and powerful genome wide association of dense genetic data with high dimensional imaging phenotypes. | Ganjgahi H et al. | β | 2018 | β |
| From a dominant to an oligogenic model of inheritance with environmental modifiers in acute intermittent porphyria. | Lenglet H et al. | β | 2018 | β |
| Functional Connectivity within the Primate Extended Amygdala Is Heritable and Associated with Early-Life Anxious Temperament. | Fox AS et al. | β | 2018 | β |
| Genetic and Environmental Influences on Fetal Growth Vary during Sensitive Periods in Pregnancy. | Workalemahu T et al. | β | 2018 | β |
| Genetic and Environmental Influences on the Associations Between Uric Acid Levels and Metabolic Syndrome Over Time. | Song YM et al. | β | 2018 | β |
| Genetic and environmental (physical fitness and sedentary activity) interaction effects on cardiometabolic risk factors in Mexican American children and adolescents. | Arya R et al. | β | 2018 | β |
| Genetic and phenotypic overlap of specific obsessive-compulsive and attention-deficit/hyperactive subtypes with Tourette syndrome. | Hirschtritt ME et al. | β | 2018 | β |
| Genetic Architecture of the Cardiovascular Risk Proteome. | Benson MD et al. | β | 2018 | β |
| Genetic influence on serum 25-hydroxyvitamin D concentration in Korean men: a cross-sectional study. | Choi S et al. | β | 2018 | β |
| Genetic Influence on the Sulcal Pits: On the Origin of the First Cortical Folds. | Le Guen Y et al. | β | 2018 | β |
| Genetic insights into fetal growth and measures of glycaemic regulation and adiposity in adulthood: a family-based study. | Hollensted M et al. | β | 2018 | β |
| Genome-wide analysis in multiple-case families: assessing the relationship between triglyceride and methylation. | Fuady AM et al. | β | 2018 | β |
| Genome-wide linkage scan for loci influencing plasma triglyceride levels. | Peralta JM et al. | β | 2018 | β |
| Genome-wide scan for circulating vascular adhesion protein-1 levels: MACROD2 as a potential transcriptional regulator of adipogenesis. | Chang YC et al. | β | 2018 | β |
| Genome-Wide Study of Subcutaneous and Visceral Adipose Tissue Reveals Novel Sex-Specific Adiposity Loci in Mexican Americans. | Gao C et al. | β | 2018 | β |
| Gut microbiota diversity across ethnicities in the United States. | Brooks AW et al. | β | 2018 | β |
| GWAS of epigenetic aging rates in blood reveals a critical role for TERT. | Lu AT et al. | β | 2018 | β |
| Heart rate variability as candidate endophenotype of social anxiety: A two-generation family study. | Harrewijn A et al. | β | 2018 | β |
| Heritability and Familiality of MMPI Personality Dimensions in the Korean Families with Schizophrenia. | Jeong HJ et al. | β | 2018 | β |
| Heritability and genetic associations of triglyceride and HDL-C levels using pedigree-based and empirical kinships. | Blackburn NB et al. | β | 2018 | β |
| Heritability and genetic correlations of heart rate variability at rest and during stress in the Oman Family Study. | MuΓ±oz ML et al. | β | 2018 | β |
| Heritability and genetic integration of anterior tooth crown variants in the South Carolina Gullah. | Stojanowski CM et al. | β | 2018 | β |
| Heritability and genome-wide association study of diffusing capacity of the lung. | Terzikhan N et al. | β | 2018 | β |
| Heritability estimates on resting state fMRI data using ENIGMA analysis pipeline. | Adhikari BM et al. | β | 2018 | β |
| Identification and functional analysis of a novel G310D variant in the insulin-like growth factor 1 receptor (IGF1R) gene associated with type 2 diabetes in American Indians. | Muller YL et al. | β | 2018 | β |
| Identity-by-descent analyses for measuring population dynamics and selection in recombining pathogens. | Henden L et al. | β | 2018 | β |
| Indirect effect inference and application to GAW20 data. | Li L et al. | β | 2018 | β |
| lme4qtl: linear mixed models with flexible covariance structure for genetic studies of related individuals. | Ziyatdinov A et al. | β | 2018 | β |
| Metabolomics Identifies Distinctive Metabolite Signatures for Measures of Glucose Homeostasis: The Insulin Resistance Atherosclerosis Family Study (IRAS-FS). | Palmer ND et al. | β | 2018 | β |
| Methods and results from the genome-wide association group at GAW20. | Wang X et al. | β | 2018 | β |
| Methods for detecting methylation by SNP interaction in GAW20 simulation. | Daw EW et al. | β | 2018 | β |
| Micro RNAs from DNA Viruses are Found Widely in Plasma in a Large Observational Human Population. | Koupenova M et al. | β | 2018 | β |
| Neurodegenerative disease biomarkers AΞ²<sub>1-40</sub>, AΞ²<sub>1-42</sub>, tau, and p-tau<sub>181</sub> in the vervet monkey cerebrospinal fluid: RelationΒ to normal aging, genetic influences, and cerebral amyloid angiopathy. | Chen JA et al. | β | 2018 | β |
| Obesity and obesogenic growth are both highly heritable and modified by diet in a nonhuman primate model, the African green monkey (Chlorocebus aethiops sabaeus). | Schmitt CA et al. | β | 2018 | β |
| Phenotypic heterogeneity in m.3243A>G mitochondrial disease: The role of nuclear factors. | Pickett SJ et al. | β | 2018 | β |
| Pleiotropy of cardiometabolic syndrome with obesity-related anthropometric traits determined using empirically derived kinships from the Busselton Health Study. | Cadby G et al. | β | 2018 | β |
| Preliminary evidence for genetic overlap between body mass index and striatal reward response. | Lancaster TM et al. | β | 2018 | β |
| Quantitative genetic analysis of anxiety trait in bipolar disorder. | Contreras J et al. | β | 2018 | β |
| Reliability of genomic predictions of complex human phenotypes. | Porto A et al. | β | 2018 | β |
| Sex-specific genetic influence on thyroid-stimulating hormone and free thyroxine levels, and interactions between measurements: KNHANES 2013-2015. | Lee YK et al. | β | 2018 | β |
| Shared genetic aetiology between cognitive performance and brain activations in language and math tasks. | Le Guen Y et al. | β | 2018 | β |
| The chaotic morphology of the left superior temporal sulcus is genetically constrained. | Le Guen Y et al. | β | 2018 | β |
| The Leiden Family Lab study on Social Anxiety Disorder: A multiplex, multigenerational family study on neurocognitive endophenotypes. | Bas-Hoogendam JM et al. | β | 2018 | β |
| The Malaria-Protective Human Glycophorin Structural Variant DUP4 Shows Somatic Mosaicism and Association with Hemoglobin Levels. | Algady W et al. | β | 2018 | β |
| Trait Mapping Approaches Through Linkage Mapping in Plants. | Kulwal PL | β | 2018 | β |
| Transcription factor 7-like 2 gene links increased in vivo insulin synthesis to type 2 diabetes. | Jainandunsing S et al. | β | 2018 | β |
| Transmissibility and familiality of NEO personality dimensions in a sample of Korean families with schizophrenia. | Kim SY et al. | β | 2018 | β |
| Using Genomic Data to Find Disease-Modifying Loci in Huntington's Disease (HD). | Holmans P et al. | β | 2018 | β |
| A combined linkage and association strategy identifies a variant near the GSTP1 gene associated with BMI in the Mexican population. | Villamil-RamΓrez H et al. | β | 2017 | β |
| Adjusting for Familial Relatedness in the Analysis of GWAS Data. | Thomson R et al. | β | 2017 | β |
| A Genome-Wide Association Study Using a Custom Genotyping Array Identifies Variants in <i>GPR158</i> Associated With Reduced Energy Expenditure in American Indians. | Piaggi P et al. | β | 2017 | β |
| A genome-wide linkage and association analysis of imputed insertions and deletions with cardiometabolic phenotypes in Mexican Americans: The Insulin Resistance Atherosclerosis Family Study. | Gao C et al. | β | 2017 | β |
| A genome-wide quantitative trait locus (QTL) linkage scan of NEO personality factors in Latino families segregating bipolar disorder. | Lee BD et al. | β | 2017 | β |
| Analysis of Whole Exome Sequencing with Cardiometabolic Traits Using Family-Based Linkage and Association in the IRAS Family Study. | Tabb KL et al. | β | 2017 | β |
| An Unexpectedly Complex Architecture for Skin Pigmentation in Africans. | Martin AR et al. | β | 2017 | β |
| APPROXIMATING PRINCIPAL GENETIC COMPONENTS OF SUBCORTICAL SHAPE. | Gutman BA et al. | β | 2017 | β |
| Associations Between Adiposity and Metabolic Syndrome Over Time: The Healthy Twin Study. | Song YM et al. | β | 2017 | β |
| A UNIFIED FRAMEWORK FOR VARIANCE COMPONENT ESTIMATION WITH SUMMARY STATISTICS IN GENOME-WIDE ASSOCIATION STUDIES. | Zhou X | β | 2017 | β |
| Behavioral and Molecular Genetics of Reading-Related AM and FM Detection Thresholds. | Bruni M et al. | β | 2017 | β |
| Chimpanzee Personality and the Arginine Vasopressin Receptor 1A Genotype. | Wilson VA et al. | β | 2017 | β |
| Combined genome-wide linkage and targeted association analysis of head circumference in autism spectrum disorder families. | Woodbury-Smith M et al. | β | 2017 | β |
| Determinants of day-night difference in blood pressure, a comparison with determinants of daytime and night-time blood pressure. | Musameh MD et al. | β | 2017 | β |
| Determinants of retinal microvascular features and their relationships in two European populations. | Kirin M et al. | β | 2017 | β |
| Estimating the Heritability of Structural and Functional Brain Connectivity in Families Affected by Attention-Deficit/Hyperactivity Disorder. | Sudre G et al. | β | 2017 | β |
| Etiology of Triarchic Psychopathy Dimensions in Chimpanzees (<i>Pan troglodytes</i>). | Latzman RD et al. | β | 2017 | β |
| Evaluating a CLL susceptibility variant in <i>ITGB2</i> in families with multiple subtypes of hematological malignancies. | Blackburn NB et al. | β | 2017 | β |
| Exome array analysis suggests an increased variant burden in families with schizophrenia. | McCarthy NS et al. | β | 2017 | β |
| Exome sequences of multiplex, multigenerational families reveal schizophrenia risk loci with potential implications for neurocognitive performance. | Kos MZ et al. | β | 2017 | β |
| Exome sequencing reveals novel genetic loci influencing obesity-related traits in Hispanic children. | Sabo A et al. | β | 2017 | β |
| Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants. | Nagy R et al. | β | 2017 | β |
| Factors influencing the age at onset in familial frontotemporal lobar dementia: Important weight of genetics. | Barbier M et al. | β | 2017 | β |
| Familial Analysis of Epistatic and Sex-Dependent Association of Genes of the Renin-Angiotensin-Aldosterone System and Blood Pressure. | Scurrah KJ et al. | β | 2017 | β |
| Familial Resemblance in Dietary Intakes of Children, Adolescents, and Parents: Does Dietary Quality Play a Role? | Bogl LH et al. | β | 2017 | β |
| Genetic analysis of age at onset variation in spinocerebellar ataxia type 2. | Figueroa KP et al. | β | 2017 | β |
| Genetic and environmental influences on the associations between change in kidney function and changes in cardiometabolic factors in Koreans. | Song YM et al. | β | 2017 | β |
| Genetic correlation of the plasma lipidome with type 2 diabetes, prediabetes and insulin resistance in Mexican American families. | Kulkarni H et al. | β | 2017 | β |
| Genetic correlations between intraocular pressure, blood pressure and primary open-angle glaucoma: a multi-cohort analysis. | Aschard H et al. | β | 2017 | β |
| Genetic Factors and Orofacial Motor Learning Selectively Influence Variability in Central Sulcus Morphology in Chimpanzees (<i>Pan troglodytes</i>). | Hopkins WD et al. | β | 2017 | β |
| Genetic Influence on Accessory Navicular Bone in the Foot: A Korean Twin and Family Study. | Cheong IY et al. | β | 2017 | β |
| Genetic loci associated with heart rate variability and their effects on cardiac disease risk. | Nolte IM et al. | β | 2017 | β |
| Genetics of serum carotenoid concentrations and their correlation with obesity-related traits in Mexican American children. | Farook VS et al. | β | 2017 | β |
| Genetic variation and gene expression across multiple tissues and developmental stages in a nonhuman primate. | Jasinska AJ et al. | β | 2017 | β |
| Genetic variation underlying renal uric acid excretion in Hispanic children: the Viva La Familia Study. | Chittoor G et al. | β | 2017 | β |
| Genome- and CD4+ T-cell methylome-wide association study of circulating trimethylamine-N-oxide in the Genetics of Lipid Lowering Drugs and Diet Network (GOLDN). | Aslibekyan S et al. | β | 2017 | β |
| Genome-wide association meta-analysis of fish and EPA+DHA consumption in 17 US and European cohorts. | Mozaffarian D et al. | β | 2017 | β |
| GENOME-WIDE INTERACTION WITH SELECTED TYPE 2 DIABETES LOCI REVEALS NOVEL LOCI FOR TYPE 2 DIABETES IN AFRICAN AMERICANS. | Keaton JM et al. | β | 2017 | β |
| Genome-wide linkage and association analysis of cardiometabolic phenotypes in Hispanic Americans. | Hellwege JN et al. | β | 2017 | β |
| Genome-wide linkage and association analysis of primary open-angle glaucoma endophenotypes in the Norfolk Island isolate. | Matovinovic E et al. | β | 2017 | β |
| Gray matter heritability in family-based and population-based studies using voxel-based morphometry. | van der Lee SJ et al. | β | 2017 | β |
| Heritability analysis with repeat measurements and its application to resting-state functional connectivity. | Ge T et al. | β | 2017 | β |
| Heritability and genetic integration of tooth size in the South Carolina Gullah. | Stojanowski CM et al. | β | 2017 | β |
| Heritability of arterial stiffness in a Brazilian population: Baependi Heart Study. | Alvim RO et al. | β | 2017 | β |
| Heritability of the melatonin synthesis variability in autism spectrum disorders. | Benabou M et al. | β | 2017 | β |
| Heritability of the morphology of optic nerve head and surrounding structures: The Healthy Twin Study. | Han JC et al. | β | 2017 | β |
| Heritability of Vascular Structure and Function: A Parent-Child Study. | Ryder JR et al. | β | 2017 | β |
| Human subcortical brain asymmetries in 15,847 people worldwide reveal effects of age and sex. | Guadalupe T et al. | β | 2017 | β |
| Identification of Two Heritable Cross-Disorder Endophenotypes for Tourette Syndrome. | Darrow SM et al. | β | 2017 | β |
| Impaired Context Processing is Attributable to Global Neuropsychological Impairment in Schizophrenia and Psychotic Bipolar Disorder. | Reilly JL et al. | β | 2017 | β |
| Inference and quantification of peptidoforms in large sample cohorts by SWATH-MS. | Rosenberger G et al. | β | 2017 | β |
| Investigating Cortical Inhibition in First-Degree Relatives and Probands in Schizophrenia. | Radhu N et al. | β | 2017 | β |
| Model-Free Linkage Analysis of a Quantitative Trait. | Morris NJ et al. | β | 2017 | β |
| Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation. | Chu AY et al. | β | 2017 | β |
| Neural Mechanism Underling Comprehension of Narrative Speech and Its Heritability: Study in a Large Population. | Babajani-Feremi A | β | 2017 | β |
| Non-linear patterns in age-related DNA methylation may reflect CD4<sup>+</sup> T cell differentiation. | Johnson ND et al. | β | 2017 | β |
| Oral Microbiota: Microbial Biomarkers of Metabolic Syndrome Independent of Host Genetic Factors. | Si J et al. | β | 2017 | β |
| Prevotella as a Hub for Vaginal Microbiota under the Influence of Host Genetics and Their Association with Obesity. | Si J et al. | β | 2017 | β |
| Sequential recruitment of study participants may inflate genetic heritability estimates. | Noce D et al. | β | 2017 | β |
| Serum phosphatidylinositol as a biomarker for bipolar disorder liability. | Knowles EE et al. | β | 2017 | β |
| Sex is a moderator of the association between NOS1AP sequence variants and QTc in two long QT syndrome founder populations: a pedigree-based measured genotype association analysis. | Winbo A et al. | β | 2017 | β |
| Shared Genetic Factors Influence Head Motion During MRI and Body Mass Index. | Hodgson K et al. | β | 2017 | β |
| Six low-penetrance SNPs for the estimation of breast cancer heritability: A family-based study in Caucasian Italian patients. | De Summa S et al. | β | 2017 | β |
| Taste Responses to Linoleic Acid: A Crowdsourced Population Study. | Garneau NL et al. | β | 2017 | β |
| Testing Two Evolutionary Theories of Human Aging with DNA Methylation Data. | Robins C et al. | β | 2017 | β |
| The effect of heritability and host genetics on the gut microbiota and metabolic syndrome. | Lim MY et al. | β | 2017 | β |
| The genetic basis of the comorbidity between cannabis use and major depression. | Hodgson K et al. | β | 2017 | β |
| The heritable basis of gene-environment interactions in cardiometabolic traits. | Poveda A et al. | β | 2017 | β |
| The lipidome in major depressive disorder: Shared genetic influence for ether-phosphatidylcholines, a plasma-based phenotype related to inflammation, and disease risk. | Knowles EEM et al. | β | 2017 | β |
| Time-dependent genetic effects on gene expression implicate aging processes. | Bryois J et al. | β | 2017 | β |
| Toward a genetic understanding of dental fear: evidence of heritability. | Randall CL et al. | β | 2017 | β |
| Triarchic Psychopathy Dimensions in Chimpanzees (<i>Pan troglodytes</i>): Investigating Associations with Genetic Variation in the Vasopressin Receptor 1A Gene. | Latzman RD et al. | β | 2017 | β |
| A multiple-phenotype imputation method for genetic studies. | Dahl A et al. | β | 2016 | β |
| Analysis of the association between host genetics, smoking, and sputum microbiota in healthy humans. | Lim MY et al. | β | 2016 | β |
| Assessment of cardiovascular disease risk factors in a genetically homogenous population of Parsi Zoroastrians in the United States: A pilot study. | Vazquez-Vidal I et al. | β | 2016 | β |
| Association Between Mortality and Heritability of the Scale of Aging Vigor in Epidemiology. | Sanders JL et al. | β | 2016 | β |
| Association of Circulating Renin and Aldosterone With Osteocalcin and Bone Mineral Density in African Ancestry Families. | Kuipers AL et al. | β | 2016 | β |
| Association of host genome with intestinal microbial composition in a large healthy cohort. | Turpin W et al. | β | 2016 | β |
| Association of TMTC2 With Human Nonsyndromic Sensorineural Hearing Loss. | Runge CL et al. | β | 2016 | β |
| A variance component method for integrated pathway analysis of gene expression data. | Quillen EE et al. | β | 2016 | β |
| Balanced translocation linked to psychiatric disorder, glutamate, and cortical structure/function. | Thomson PA et al. | β | 2016 | β |
| Bayesian Variable Selection in Multilevel Item Response Theory Models with Application in Genomics. | Fragoso TM et al. | β | 2016 | β |
| Comparing estimates of genetic variance across different relationship models. | Legarra A | β | 2016 | β |
| Constrained multivariate association with longitudinal phenotypes. | Melton PE et al. | β | 2016 | β |
| Dopamine pathway gene variants may modulate cognitive performance in the DHS - Mind Study. | Martelle SE et al. | β | 2016 | β |
| Elucidating the evolution of hominid dentition in the age of phenomics, modularity, and quantitative genetics. | Hlusko LJ | β | 2016 | β |
| Erytrocyte-related phenotypes and genetic susceptibility to thrombosis. | Remacha AF et al. | β | 2016 | β |
| Exome Sequence Data From Multigenerational Families Implicate AMPA Receptor Trafficking in Neurocognitive Impairment and Schizophrenia Risk. | Kos MZ et al. | β | 2016 | β |
| Exploring correlation between bone metabolism markers and densitometric traits in extended families from Spain. | Athanasiadis G et al. | β | 2016 | β |
| Familial aggregation and heritability of the melancholic and atypical subtypes of depression. | Lamers F et al. | β | 2016 | β |
| Familial Aggregation and Heritability of Wuchereria bancrofti Infection. | Chesnais CB et al. | β | 2016 | β |
| Filtering genetic variants and placing informative priors based on putative biological function. | Friedrichs S et al. | β | 2016 | β |
| Finding potential cis-regulatory loci using allele-specific chromatin accessibility as weights in a kernel-based variance component test. | Peralta JM et al. | β | 2016 | β |
| Foundational Principles for Large-Scale Inference: Illustrations Through Correlation Mining. | Hero AO et al. | β | 2016 | β |
| Gating Deficit Heritability and Correlation With Increased Clinical Severity in Schizophrenia Patients With Positive Family History. | Greenwood TA et al. | β | 2016 | β |
| Gene expression in large pedigrees: analytic approaches. | Cantor RM et al. | β | 2016 | β |
| Genetic assessment of additional endophenotypes from the Consortium on the Genetics of Schizophrenia Family Study. | Greenwood TA et al. | β | 2016 | β |
| Genetic complexity at expression quantitative trait loci. | Cantor RM et al. | β | 2016 | β |
| Genetic contributions to circadian activity rhythm and sleep pattern phenotypes in pedigrees segregating for severe bipolar disorder. | Pagani L et al. | β | 2016 | β |
| Genetic Correlation between Body Fat Percentage and Cardiorespiratory Fitness Suggests Common Genetic Etiology. | Schnurr TM et al. | β | 2016 | β |
| Genetic determinants of cardiometabolic risk factors in rural families in Brazil. | Pena GG et al. | β | 2016 | β |
| Genetic Determinants of Thrombin Generation and Their Relation to Venous Thrombosis: Results from the GAIT-2 Project. | Martin-Fernandez L et al. | β | 2016 | β |
| Genetic effects on serum testosterone and sex hormone-binding globulin in men: a Korean twin and family study. | Sung J et al. | β | 2016 | β |
| Genetic influence on the association between bone mineral density and testosterone in Korean men. | Shin J et al. | β | 2016 | β |
| Genetic loci for Epstein-Barr virus nuclear antigen-1 are associated with risk of multiple sclerosis. | Zhou Y et al. | β | 2016 | β |
| Genetic variants in RBFOX3 are associated with sleep latency. | Amin N et al. | β | 2016 | β |
| Genome- and epigenome-wide association study of hypertriglyceridemic waist in Mexican American families. | Mamtani M et al. | β | 2016 | β |
| Genome-wide association analysis of self-reported events in 6135 individuals and 252 827 controls identifies 8 loci associated with thrombosis. | Hinds DA et al. | β | 2016 | β |
| Genome-wide association of trajectories of systolic blood pressure change. | Justice AE et al. | β | 2016 | β |
| Genome-wide association study of antibody responses to Plasmodium falciparum candidate vaccine antigens. | Milet J et al. | β | 2016 | β |
| Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci. | Walford GA et al. | β | 2016 | β |
| Genome-Wide Interaction with Insulin Secretion Loci Reveals Novel Loci for Type 2 Diabetes in African Americans. | Keaton JM et al. | β | 2016 | β |
| Genome-wide linkage analysis and regional fine mapping identified variants in the RYR3 gene as a novel quantitative trait locus for circulating adiponectin in Chinese population. | Chang YC et al. | β | 2016 | β |
| Genome-wide linkage on chromosome 10q26 for a dimensional scale of major depression. | Knowles EE et al. | β | 2016 | β |
| Genome-wide significant loci for addiction and anxiety. | Hodgson K et al. | β | 2016 | β |
| GWAS and transcriptional analysis prioritize ITPR1 and CNTN4 for a serum uric acid 3p26 QTL in Mexican Americans. | Chittoor G et al. | β | 2016 | β |
| Heritability and reliability of automatically segmented human hippocampal formation subregions. | Whelan CD et al. | β | 2016 | β |
| Heritability of dietary traits that contribute to nephrolithiasis in a cohort of adult sibships. | Lieske JC et al. | β | 2016 | β |
| Heritability of Hippocampal Formation Sub-region Volumes. | Greenspan KS et al. | β | 2016 | β |
| Heritability of major depressive and comorbid anxiety disorders in multi-generational families at high risk for depression. | Guffanti G et al. | β | 2016 | β |
| Heritability of the shape of subcortical brain structures in the general population. | Roshchupkin GV et al. | β | 2016 | β |
| Heritability of Thoracic Spine Curvature and Genetic Correlations With Other Spine Traits: The Framingham Study. | Yau MS et al. | β | 2016 | β |
| Improved Performance of Dynamic Measures of Insulin Response Over Surrogate Indices to Identify Genetic Contributors of Type 2 Diabetes: The GUARDIAN Consortium. | Palmer ND et al. | β | 2016 | β |
| Independent test assessment using the extreme value distribution theory. | Almeida M et al. | β | 2016 | β |
| Linkage and association analysis of circulating vitamin D and parathyroid hormone identifies novel loci in Alaska Native Yup'ik people. | Aslibekyan S et al. | β | 2016 | β |
| Lipidomic analyses in epidemiology. | Mundra PA et al. | β | 2016 | β |
| Lipidomic risk score independently and cost-effectively predicts risk of future type 2 diabetes: results from diverse cohorts. | Mamtani M et al. | β | 2016 | β |
| Methylation of SOCS3 is inversely associated with metabolic syndrome in an epigenome-wide association study of obesity. | Ali O et al. | β | 2016 | β |
| Multidimensional heritability analysis of neuroanatomical shape. | Ge T et al. | β | 2016 | β |
| Multipoint genome-wide linkage scan for nonword repetition in a multigenerational family further supports chromosome 13q as a locus for verbal trait disorders. | Truong DT et al. | β | 2016 | β |
| Pathway-based analyses. | Kent JW | β | 2016 | β |
| Physical activity and FTO genotype by physical activity interactive influences on obesity. | Kim JY et al. | β | 2016 | β |
| Plasma Fibroblast Growth Factor 23: Clinical Correlates and Association With Cardiovascular Disease and Mortality in the Framingham Heart Study. | Haring R et al. | β | 2016 | β |
| Prosaposin is a regulator of progranulin levels and oligomerization. | Nicholson AM et al. | β | 2016 | β |
| Recurrent major depression and right hippocampal volume: A bivariate linkage and association study. | Mathias SR et al. | β | 2016 | β |
| Rodent models for resolving extremes of exercise and health. | Garton FC et al. | β | 2016 | β |
| RVFam: an R package for rare variant association analysis with family data. | Chen MH et al. | β | 2016 | β |
| Single nucleotide polymorphisms in an intergenic chromosome 2q region associated with tissue factor pathway inhibitor plasma levels and venous thromboembolism. | Dennis J et al. | β | 2016 | β |
| Social disinhibition is a heritable subphenotype of tics in Tourette syndrome. | Hirschtritt ME et al. | β | 2016 | β |
| Socioeconomic position in young adulthood is associated with BMI in Australian families. | Scurrah KJ et al. | β | 2016 | β |
| solarius: an R interface to SOLAR for variance component analysis in pedigrees. | Ziyatdinov A et al. | β | 2016 | β |
| The Central Role of KNG1 Gene as a Genetic Determinant of Coagulation Pathway-Related Traits: Exploring Metaphenotypes. | Brunel H et al. | β | 2016 | β |
| The integration of quantitative genetics, paleontology, and neontology reveals genetic underpinnings of primate dental evolution. | Hlusko LJ et al. | β | 2016 | β |
| The Pharmacogenomics of Anti-Platelet Intervention (PAPI) Study: Variation in Platelet Response to Clopidogrel and Aspirin. | Bozzi LM et al. | β | 2016 | β |
| Toward Precision Medicine: TBC1D4 Disruption Is Common Among the Inuit and Leads to Underdiagnosis of Type 2 Diabetes. | Manousaki D et al. | β | 2016 | β |
| Vitamin D heritability and effect of pregnancy status in Vervet monkeys (Chlorocebus aethiops sabaeus) under conditions of modest and high dietary supplementation. | Chittoor G et al. | β | 2016 | β |
| A Comprehensive Analysis of Common and Rare Variants to Identify Adiposity Loci in Hispanic Americans: The IRAS Family Study (IRASFS). | Gao C et al. | β | 2015 | β |
| Adiponectin Levels and Longitudinal Changes in Metabolic Syndrome: The Healthy Twin Study. | Song YM et al. | β | 2015 | β |
| A family-specific linkage analysis of blood lipid response to fenofibrate in the Genetics of Lipid Lowering Drug and Diet Network. | Hidalgo B et al. | β | 2015 | β |
| A general unified framework to assess the sampling variance of heritability estimates using pedigree or marker-based relationships. | Visscher PM et al. | β | 2015 | β |
| A genome-wide linkage and association study of musical aptitude identifies loci containing genes related to inner ear development and neurocognitive functions. | Oikkonen J et al. | β | 2015 | β |
| Analysis of a cardiovascular disease genetic risk score in the Diabetes Heart Study. | Raffield LM et al. | β | 2015 | β |
| An Effective Method to Identify Heritable Components from Multivariate Phenotypes. | Sun J et al. | β | 2015 | β |
| An epigenetic map of age-associated autosomal loci in northern European families at high risk for the metabolic syndrome. | Ali O et al. | β | 2015 | β |
| An Islet-Targeted Genome-Wide Association Scan Identifies Novel Genes Implicated in Cytokine-Mediated Islet Stress in Type 2 Diabetes. | Sharma PR et al. | β | 2015 | β |
| A Phenomic Scan of the Norfolk Island Genetic Isolate Identifies a Major Pleiotropic Effect Locus Associated with Metabolic and Renal Disorder Markers. | Benton MC et al. | β | 2015 | β |
| A re-formulation of generalized linear mixed models to fit family data in genetic association studies. | Wang T et al. | β | 2015 | β |
| A retrospective examination of mean relative telomere length in the Tasmanian Familial Hematological Malignancies Study. | Blackburn NB et al. | β | 2015 | β |
| A Sequence Kernel Association Test for Dichotomous Traits in Family Samples under a Generalized Linear Mixed Model. | Yan Q et al. | β | 2015 | β |
| Associating Multivariate Quantitative Phenotypes with Genetic Variants in Family Samples with a Novel Kernel Machine Regression Method. | Yan Q et al. | β | 2015 | β |
| Association of Aging-Related Endophenotypes With Mortality in 2 Cohort Studies: the Long Life Family Study and the Health, Aging and Body Composition Study. | Singh J et al. | β | 2015 | β |
| Association of COMT and TPH-2 genes with DSM-5 based PTSD symptoms. | Goenjian AK et al. | β | 2015 | β |
| Association of substance dependence phenotypes in the COGA sample. | Wetherill L et al. | β | 2015 | β |
| Associations of the Inflammatory Marker YKL-40 with Measures of Obesity and Dyslipidaemia in Individuals at High Risk of Type 2 Diabetes. | Thomsen SB et al. | β | 2015 | β |
| A systematic heritability analysis of the human whole blood transcriptome. | Huan T et al. | β | 2015 | β |
| Atherogenic dyslipidemia in children: evaluation of clinical, biochemical and genetic aspects. | Montali A et al. | β | 2015 | β |
| Behavioral and brain asymmetries in primates: a preliminary evaluation of two evolutionary hypotheses. | Hopkins WD et al. | β | 2015 | β |
| Brain structure-function associations in multi-generational families genetically enriched for bipolar disorder. | Fears SC et al. | β | 2015 | β |
| Cortical Folding of the Primate Brain: An Interdisciplinary Examination of the Genetic Architecture, Modularity, and Evolvability of a Significant Neurological Trait in Pedigreed Baboons (Genus Papio). | Atkinson EG et al. | β | 2015 | β |
| Detection of a quantitative trait locus associated with resistance to infection with Trichuris suis in pigs. | Skallerup P et al. | β | 2015 | β |
| Determination of DNA methylation levels using Illumina HumanMethylation450 BeadChips. | Carless MA | β | 2015 | β |
| Discovering schizophrenia endophenotypes in randomly ascertained pedigrees. | Glahn DC et al. | β | 2015 | β |
| Dissecting metabolic syndrome components: data from an epidemiologic survey in a genetic isolate. | Biino G et al. | β | 2015 | β |
| Distribution and heritability of diurnal preference (chronotype) in a rural Brazilian family-based cohort, the Baependi study. | von Schantz M et al. | β | 2015 | β |
| Effect of VRTN gene polymorphisms on Duroc pig production and carcass traits, and their genetic relationships. | Nakano H et al. | β | 2015 | β |
| Effects of copy number variable regions on local gene expression in white blood cells of Mexican Americans. | Blackburn A et al. | β | 2015 | β |
| Empirical characteristics of family-based linkage to a complex trait: the ADIPOQ region and adiponectin levels. | Hellwege JN et al. | β | 2015 | β |
| Estimation of heritability for varied indexes of handedness. | Lien YJ et al. | β | 2015 | β |
| Evaluation of neurotrophic tyrosine receptor kinase 2 (NTRK2) as a positional candidate gene for variation in estimated glomerular filtration rate (eGFR) in Mexican American participants of San Antonio Family Heart study. | Thameem F et al. | β | 2015 | β |
| Event-related potential and time-frequency endophenotypes for schizophrenia and psychotic bipolar disorder. | Ethridge LE et al. | β | 2015 | β |
| Evolutionary context for the association of Ξ³-globin, serum uric acid, and hypertension in African Americans. | Shriner D et al. | β | 2015 | β |
| Factor structure and heritability of endophenotypes in schizophrenia: findings from the Consortium on the Genetics of Schizophrenia (COGS-1). | Seidman LJ et al. | β | 2015 | β |
| Failing beta-cell adaptation in South Asian families with a high risk of type 2 diabetes. | Jainandunsing S et al. | β | 2015 | β |
| Family-Based Association Study of Pulmonary Function in a Population in Northeast Asia. | Son HY et al. | β | 2015 | β |
| Family-based genome scan for age at onset of late-onset Alzheimer's disease in whole exome sequencing data. | Saad M et al. | β | 2015 | β |
| Fast and powerful heritability inference for family-based neuroimaging studies. | Ganjgahi H et al. | β | 2015 | β |
| Fatty acids linked to cardiovascular mortality are associated with risk factors. | Ebbesson SO et al. | β | 2015 | β |
| Genetic and environmental influence on the association between testosterone, sex hormone-binding globulin and body composition in Korean men. | Lee K et al. | β | 2015 | β |
| Genetic and phenotypic correlations between surrogate measures of insulin release obtained from OGTT data. | Gjesing AP et al. | β | 2015 | β |
| Genetic associations and shared environmental effects on the skin microbiome of Korean twins. | Si J et al. | β | 2015 | β |
| Genetic basis in motor skill and hand preference for tool use in chimpanzees (Pan troglodytes). | Hopkins WD et al. | β | 2015 | β |
| Genetic contribution to the variance of blood pressure and heart rate: a systematic review and meta-regression of twin studies. | Wang B et al. | β | 2015 | β |
| Genetic determinants of platelet large-cell ratio, immature platelet fraction, and other platelet-related phenotypes. | Pujol-Moix N et al. | β | 2015 | β |
| Genetic evaluation with major genes and polygenic inheritance when some animals are not genotyped using gene content multiple-trait BLUP. | Legarra A et al. | β | 2015 | β |
| Genetic influence on left ventricular structure and function: a Korean twin and family study. | Noh HM et al. | β | 2015 | β |
| Genetic influences on response to novel objects and dimensions of personality in Papio baboons. | Johnson Z et al. | β | 2015 | β |
| Genetic Modifiers of Age at Onset in Carriers of the G206A Mutation in PSEN1 With Familial Alzheimer Disease Among Caribbean Hispanics. | Lee JH et al. | β | 2015 | β |
| Genetics of kidney disease and related cardiometabolic phenotypes in Zuni Indians: the Zuni Kidney Project. | Laston SL et al. | β | 2015 | β |
| Genetics of Sleep Disorders. | Gehrman PR et al. | β | 2015 | β |
| Genetic susceptibility to dental caries differs between the sexes: a family-based study. | Shaffer JR et al. | β | 2015 | β |
| Genetic Variants Associated With Quantitative Glucose Homeostasis Traits Translate to Type 2 Diabetes in Mexican Americans: The GUARDIAN (Genetics Underlying Diabetes in Hispanics) Consortium. | Palmer ND et al. | β | 2015 | β |
| Genetic variants modulating CRIPTO serum levels identified by genome-wide association study in Cilento isolates. | Ruggiero D et al. | β | 2015 | β |
| Genome-Wide Association Study and Linkage Analysis of the Healthy Aging Index. | Minster RL et al. | β | 2015 | β |
| Genome-wide association study of kidney function decline in individuals of European descent. | Gorski M et al. | β | 2015 | β |
| Genome-wide genetic investigation of serological measures of common infections. | Rubicz R et al. | β | 2015 | β |
| Genome-wide identification of microRNA expression quantitative trait loci. | Huan T et al. | β | 2015 | β |
| Genome-wide linkage and positional association analyses identify associations of novel AFF3 and NTM genes with triglycerides: the GenSalt study. | Li C et al. | β | 2015 | β |
| Genome-wide significant linkage of schizophrenia-related neuroanatomical trait to 12q24. | Sprooten E et al. | β | 2015 | β |
| Heritability and genetic association analysis of neuroimaging measures in the Diabetes Heart Study. | Raffield LM et al. | β | 2015 | β |
| Heritability and genetics of serum dickkopf 1 levels in African ancestry families. | Kuipers AL et al. | β | 2015 | β |
| Heritability of cognitive traits among siblings with a parental history of Alzheimer's disease. | Darst BF et al. | β | 2015 | β |
| Heritability of subcortical and limbic brain volume and shape in multiplex-multigenerational families with schizophrenia. | Roalf DR et al. | β | 2015 | β |
| Heritability of telomere length in a study of long-lived families. | Honig LS et al. | β | 2015 | β |
| Heritability of the Human Craniofacial Complex. | Ε eΕ‘elj M et al. | β | 2015 | β |
| Impact of PTBP1 rs11085226 on glucose-stimulated insulin release in adult Danes. | Hansen TH et al. | β | 2015 | β |
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| Left ventricular mechanical function: clinical correlates, heritability, and association with parental heart failure. | Cheng S et al. | β | 2015 | β |
| Lifetime prevalence, age of risk, and genetic relationships of comorbid psychiatric disorders in Tourette syndrome. | Hirschtritt ME et al. | β | 2015 | β |
| Linkage Analysis of Urine Arsenic Species Patterns in the Strong Heart Family Study. | Gribble MO et al. | β | 2015 | β |
| Longitudinal relationships of metabolic syndrome and obesity with kidney function: Healthy Twin Study. | Song YM et al. | β | 2015 | β |
| Long-term neural and physiological phenotyping of a single human. | Poldrack RA et al. | β | 2015 | β |
| Massively expedited genome-wide heritability analysis (MEGHA). | Ge T et al. | β | 2015 | β |
| Medial Demons Registration Localizes The Degree of Genetic Influence Over Subcortical Shape Variability: An N= 1480 Meta-Analysis. | Gutman BA et al. | β | 2015 | β |
| Methods of integrating data to uncover genotype-phenotype interactions. | Ritchie MD et al. | β | 2015 | β |
| Multi-level block permutation. | Winkler AM et al. | β | 2015 | β |
| Neuropsychological and dimensional behavioral trait profiles in Costa Rican ADHD sib pairs: Potential intermediate phenotypes for genetic studies. | Peskin VA et al. | β | 2015 | β |
| New genetic loci link adipose and insulin biology to body fat distribution. | Shungin D et al. | β | 2015 | β |
| Novel epigenetic determinants of type 2 diabetes in Mexican-American families. | Kulkarni H et al. | β | 2015 | β |
| Novel loci associated with usual sleep duration: the CHARGE Consortium Genome-Wide Association Study. | Gottlieb DJ et al. | β | 2015 | β |
| On the Estimation of Heritability with Family-Based and Population-Based Samples. | Kim Y et al. | β | 2015 | β |
| Pedigree-Free Descent-Based Gene Mapping from Population Samples. | Glazner C et al. | β | 2015 | β |
| Pleiotropic locus for emotion recognition and amygdala volume identified using univariate and bivariate linkage. | Knowles EE et al. | β | 2015 | β |
| Population-based in vitro hazard and concentration-response assessment of chemicals: the 1000 genomes high-throughput screening study. | Abdo N et al. | β | 2015 | β |
| Pursuit eye movements as an intermediate phenotype across psychotic disorders: Evidence from the B-SNIP study. | Lencer R et al. | β | 2015 | β |
| Quality control of genotypes using heritability estimates of gene content at the marker. | Forneris NS et al. | β | 2015 | β |
| Quantitative variability of 342 plasma proteins in a human twin population. | Liu Y et al. | β | 2015 | β |
| Refined phenotyping identifies links between preeclampsia and related diseases in a Norwegian preeclampsia family cohort. | Thomsen LC et al. | β | 2015 | β |
| Regressing to Prior Response Preference After Set Switching Implicates Striatal Dysfunction Across Psychotic Disorders: Findings From the B-SNIP Study. | Hill SK et al. | β | 2015 | β |
| Relaxed genetic control of cortical organization in human brains compared with chimpanzees. | GΓ³mez-Robles A et al. | β | 2015 | β |
| Replicated analysis of the genetic architecture of quantitative traits in two wild great tit populations. | Santure AW et al. | β | 2015 | β |
| Sequencing of candidate genes in Dominican families implicates both rare exonic and common non-exonic variants for carotid intima-media thickness at bifurcation. | Wang L et al. | β | 2015 | β |
| Sequencing strategies and characterization of 721 vervet monkey genomes for future genetic analyses of medically relevant traits. | Huang YS et al. | β | 2015 | β |
| Serum antibody responses in pigs trickle-infected with Ascaris and Trichuris: Heritabilities and associations with parasitological findings. | Kringel H et al. | β | 2015 | β |
| Serum uric acid concentrations and SLC2A9 genetic variation in Hispanic children: the Viva La Familia Study. | Voruganti VS et al. | β | 2015 | β |
| Shared genetic factors influence amygdala volumes and risk for alcoholism. | Dager AD et al. | β | 2015 | β |
| Shared Genetic Factors of Anxiety and Depression Symptoms in a Brazilian Family-Based Cohort, the Baependi Heart Study. | Taporoski TP et al. | β | 2015 | β |
| Shared genetic variance between obesity and white matter integrity in Mexican Americans. | Spieker EA et al. | β | 2015 | β |
| TAS2R bitter taste receptors regulate thyroid function. | Clark AA et al. | β | 2015 | β |
| The contribution of genetics and early rearing experiences to hierarchical personality dimensions in chimpanzees (Pan troglodytes). | Latzman RD et al. | β | 2015 | β |
| The more <i>g</i>-loaded, the more heritable, evolvable, and phenotypically variable: Homology with humans in chimpanzee cognitive abilities. | Woodley Of Menie MA et al. | β | 2015 | β |
| The type 2 diabetes risk allele of TMEM154-rs6813195 associates with decreased beta cell function in a study of 6,486 Danes. | Harder MN et al. | β | 2015 | β |
| Third trimester fetal heart rate predicts phenotype and mutation burden in the type 1 long QT syndrome. | Winbo A et al. | β | 2015 | β |
| Tic symptom dimensions and their heritabilities in Tourette's syndrome. | de Haan MJ et al. | β | 2015 | β |
| Transcriptomic identification of ADH1B as a novel candidate gene for obesity and insulin resistance in human adipose tissue in Mexican Americans from the Veterans Administration Genetic Epidemiology Study (VAGES). | Winnier DA et al. | β | 2015 | β |
| Unraveling the intrafamilial correlations and heritability of tumor types in MEN1: a Groupe d'Γ©tude des Tumeurs Endocrines study. | Thevenon J et al. | β | 2015 | β |
| Variation in PPARG is associated with longitudinal change in insulin resistance in Mexican Americans at risk for type 2 diabetes. | Black MH et al. | β | 2015 | β |
| White Matter Lesion Progression: Genome-Wide Search for Genetic Influences. | Hofer E et al. | β | 2015 | β |
| Working memory impairment in probands with schizoaffective disorder and first degree relatives of schizophrenia probands extend beyond deficits predicted by generalized neuropsychological impairment. | Kristian Hill S et al. | β | 2015 | β |
| A general approach for haplotype phasing across the full spectrum of relatedness. | O'Connell J et al. | β | 2014 | β |
| A genome-wide association study in the genetic analysis of idiopathic thrombophilia project suggests sex-specific regulation of mitochondrial DNA levels. | LΓ³pez S et al. | β | 2014 | β |
| A genomewide study of body mass index and its genetic correlation with thromboembolic risk. Results from the GAIT project. | Souto JC et al. | β | 2014 | β |
| ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample. | Quillen EE et al. | β | 2014 | β |
| An exploration of heterogeneity in genetic analysis of complex pedigrees: linkage and association using whole genome sequencing data in the MAP4 region. | Bull SB et al. | β | 2014 | β |
| A novel method, the Variant Impact On Linkage Effect Test (VIOLET), leads to improved identification of causal variants in linkage regions. | Martin LJ et al. | β | 2014 | β |
| Association of common genetic variants with diabetes and metabolic syndrome related traits in the Arizona Insulin Resistance registry: a focus on Mexican American families in the Southwest. | DeMenna J et al. | β | 2014 | β |
| A variance component-based gene burden test. | Peralta JM et al. | β | 2014 | β |
| Behavioral response inhibition in psychotic disorders: diagnostic specificity, familiality and relation to generalized cognitive deficit. | Ethridge LE et al. | β | 2014 | β |
| Bivariate association analysis of longitudinal phenotypes in families. | Melton PE et al. | β | 2014 | β |
| Cardiovascular risk in Gullah African Americans with high familial risk of type 2 diabetes mellitus: project SuGAR. | Hunt KJ et al. | β | 2014 | β |
| Chimpanzee intelligence is heritable. | Hopkins WD et al. | β | 2014 | β |
| Clustering of body composition, blood pressure and physical activity in Portuguese families. | de Chaves RN et al. | β | 2014 | β |
| Combined linkage and family-based association analysis improves candidate gene detection in Genetic Analysis Workshop 18 simulation data. | Li Y et al. | β | 2014 | β |
| Combined linkage disequilibrium and linkage mapping: Bayesian multilocus approach. | Pikkuhookana P et al. | β | 2014 | β |
| COMBINING META- AND MEGA- ANALYTIC APPROACHES FOR MULTI-SITE DIFFUSION IMAGING BASED GENETIC STUDIES: FROM THE ENIGMA-DTI WORKING GROUP. | Jahanshad N et al. | β | 2014 | β |
| Common genetic variants and gene expression associated with white matter microstructure in the human brain. | Sprooten E et al. | β | 2014 | β |
| Common genetic variants on 6q24 associated with exceptional episodic memory performance in the elderly. | Barral S et al. | β | 2014 | β |
| Common variants in BDNF, FAIM2, FTO, MC4R, NEGR1, and SH2B1 show association with obesity-related variables in Spanish Roma population. | Poveda A et al. | β | 2014 | β |
| Common variants in UMOD associate with urinary uromodulin levels: a meta-analysis. | Olden M et al. | β | 2014 | β |
| Comparing the utility of homogeneous subtypes of cocaine use and related behaviors with DSM-IV cocaine dependence as traits for genetic association analysis. | Bi J et al. | β | 2014 | β |
| Comparison of the heritability of schizophrenia and endophenotypes in the COGS-1 family study. | Light G et al. | β | 2014 | β |
| Complex pedigrees in the sequencing era: to track transmissions or decorrelate? | Li D et al. | β | 2014 | β |
| Corpus callosum size is highly heritable in humans, and may reflect distinct genetic influences on ventral and rostral regions. | Woldehawariat G et al. | β | 2014 | β |
| Correlation analysis of genetic admixture and social identification with body mass index in a Native American community. | Norden-Krichmar TM et al. | β | 2014 | β |
| Determinants of intrathoracic adipose tissue volume and associations with cardiovascular disease risk factors in Amish. | Liu X et al. | β | 2014 | β |
| Diagnostic specificity and familiality of early versus late evoked potentials to auditory paired stimuli across the schizophrenia-bipolar psychosis spectrum. | Hamm JP et al. | β | 2014 | β |
| Elevated antisaccade error rate as an intermediate phenotype for psychosis across diagnostic categories. | Reilly JL et al. | β | 2014 | β |
| Emotion recognition deficits in schizophrenia-spectrum disorders and psychotic bipolar disorder: Findings from the Bipolar-Schizophrenia Network on Intermediate Phenotypes (B-SNIP) study. | Ruocco AC et al. | β | 2014 | β |
| Evaluation of estimated genetic values and their application to genome-wide investigation of systolic blood pressure. | Quillen EE et al. | β | 2014 | β |
| Familial aggregation of tobacco use behaviors among Amish men. | Nugent KL et al. | β | 2014 | β |
| Familiality and clinical outcomes of sleep disturbances in major depressive and bipolar disorders. | Lai YC et al. | β | 2014 | β |
| Family-based association analysis of alcohol dependence criteria and severity. | Wetherill L et al. | β | 2014 | β |
| Functional study of a genetic marker allele associated with resistance to Ascaris suum in pigs. | Skallerup P et al. | β | 2014 | β |
| Further evidence for phenotypic signatures of hybridization in descendant baboon populations. | Ackermann RR et al. | β | 2014 | β |
| Gene-by-age effects on BMI from birth to adulthood: the Fels Longitudinal Study. | Choh AC et al. | β | 2014 | β |
| Generalization of associations of kidney-related genetic loci to American Indians. | Franceschini N et al. | β | 2014 | β |
| Genetic evaluation and application of posterior cranial fossa traits as endophenotypes for Chiari type I malformation. | Markunas CA et al. | β | 2014 | β |
| Genetic implication of a novel thiamine transporter in human hypertension. | Zhang K et al. | β | 2014 | β |
| Genetic influences of sports participation in Portuguese families. | Seabra AF et al. | β | 2014 | β |
| Genetic influences on hallux valgus in Koreans: the healthy twin study. | Lee CH et al. | β | 2014 | β |
| Genetic influences on receptive joint attention in chimpanzees (Pan troglodytes). | Hopkins WD et al. | β | 2014 | β |
| Genetic interactions affecting human gene expression identified by variance association mapping. | Brown AA et al. | β | 2014 | β |
| Genetics of microstructure of the corpus callosum in older adults. | Kanchibhotla SC et al. | β | 2014 | β |
| Genetic variants associated with lung function: the long life family study. | Thyagarajan B et al. | β | 2014 | β |
| Genetic variants in selenoprotein P plasma 1 gene (SEPP1) are associated with fasting insulin and first phase insulin response in Hispanics. | Hellwege JN et al. | β | 2014 | β |
| Genetic variation in MTNR1B is associated with gestational diabetes mellitus and contributes only to the absolute level of beta cell compensation in Mexican Americans. | Ren J et al. | β | 2014 | β |
| Genome-wide association studies identified novel loci for non-high-density lipoprotein cholesterol and its postprandial lipemic response. | An P et al. | β | 2014 | β |
| Genome-wide association study identifies multiple loci associated with both mammographic density and breast cancer risk. | LindstrΓΆm S et al. | β | 2014 | β |
| Genome-wide association study of L-arginine and dimethylarginines reveals novel metabolic pathway for symmetric dimethylarginine. | LΓΌneburg N et al. | β | 2014 | β |
| Genome-wide association study of periodontal health measured by probing depth in adults ages 18-49 years. | Shaffer JR et al. | β | 2014 | β |
| Genome-wide association study of primary dentition pit-and-fissure and smooth surface caries. | Zeng Z et al. | β | 2014 | β |
| Genome-wide family-based linkage analysis of exome chip variants and cardiometabolic risk. | Hellwege JN et al. | β | 2014 | β |
| Genome-wide genetic and transcriptomic investigation of variation in antibody response to dietary antigens. | Rubicz R et al. | β | 2014 | β |
| Genome-wide linkage and regional association study of blood pressure response to the cold pressor test in Han Chinese: the genetic epidemiology network of salt sensitivity study. | Yang X et al. | β | 2014 | β |
| Genome-wide significant localization for working and spatial memory: Identifying genes for psychosis using models of cognition. | Knowles EE et al. | β | 2014 | β |
| Genomic view of bipolar disorder revealed by whole genome sequencing in a genetic isolate. | Georgi B et al. | β | 2014 | β |
| Genotype by energy expenditure interaction and body composition traits: The Portuguese Healthy Family Study. | Santos DM et al. | β | 2014 | β |
| Genotype by sex and genotype by age interactions with sedentary behavior: the Portuguese Healthy Family Study. | Santos DM et al. | β | 2014 | β |
| Heritability and other determinants of left ventricular diastolic function in the family-based population study. | Kloch-Badelek M et al. | β | 2014 | β |
| Heritability of and mortality prediction with a longevity phenotype: the healthy aging index. | Sanders JL et al. | β | 2014 | β |
| Heritability of cardiovascular risk factors in a Chinese population--Taichung Community Health Study and Family Cohort. | Lin CC et al. | β | 2014 | β |
| Heritability of phenotypes associated with glucose homeostasis and adiposity in a rural area of Brazil. | Pena GG et al. | β | 2014 | β |
| Heritability of urinary traits that contribute to nephrolithiasis. | Lieske JC et al. | β | 2014 | β |
| Heritable changes in regional cortical thickness with age. | Chouinard-Decorte F et al. | β | 2014 | β |
| High heritability and genetic correlation of intravenous glucose- and tolbutamide-induced insulin secretion among non-diabetic family members of type 2 diabetic patients. | Gjesing AP et al. | β | 2014 | β |
| Human heart rate: heritability of resting and stress values in twin pairs, and influence of genetic variation in the adrenergic pathway at a microribonucleic acid (microrna) motif in the 3'-UTR of cytochrome b561 [corrected]. | Zhang K et al. | β | 2014 | β |
| Human plasma lipidome is pleiotropically associated with cardiovascular risk factors and death. | Bellis C et al. | β | 2014 | β |
| Identity-by-descent graphs offer a flexible framework for imputation and both linkage and association analyses. | Blue EM et al. | β | 2014 | β |
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| On family-based genome-wide association studies with large pedigrees: observations and recommendations. | Fardo DW et al. | β | 2014 | β |
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| Personality Traits in Rhesus Macaques (<i>Macaca mulatta</i>) Are Heritable but Do Not Predict Reproductive Output. | Brent LJ et al. | β | 2014 | β |
| Plasma dihydroceramide species associate with waist circumference in Mexican American families. | Mamtani M et al. | β | 2014 | β |
| Plasma levels of soluble interleukin 1 receptor accessory protein are reduced in obesity. | Bozaoglu K et al. | β | 2014 | β |
| Plasma lipidome is independently associated with variability in metabolic syndrome in Mexican American families. | Kulkarni H et al. | β | 2014 | β |
| Polymorphisms in inflammatory and immune response genes associated with cerebral cavernous malformation type 1 severity. | Choquet H et al. | β | 2014 | β |
| Preeclampsia and cardiovascular disease share genetic risk factors on chromosome 2q22. | LΓΈset M et al. | β | 2014 | β |
| Quantitative Genetics of Response to Novelty and Other Stimuli by Infant Rhesus Macaques (<i>Macaca mulatta</i>) Across Three Behavioral Assessments. | Fawcett GL et al. | β | 2014 | β |
| Quantitative linkage for autism spectrum disorders symptoms in attention-deficit/hyperactivity disorder: significant locus on chromosome 7q11. | Nijmeijer JS et al. | β | 2014 | β |
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| Relative influence of heritability, environment and genetics on serum sclerostin. | Kuipers AL et al. | β | 2014 | β |
| Replication of obesity and diabetes-related SNP associations in individuals from YucatΓ‘n, MΓ©xico. | Hernandez-Escalante VM et al. | β | 2014 | β |
| Replication of the effect of SLC2A9 genetic variation on serum uric acid levels in American Indians. | Voruganti VS et al. | β | 2014 | β |
| Resting state electroencephalogram oscillatory abnormalities in schizophrenia and psychotic bipolar patients and their relatives from the bipolar and schizophrenia network on intermediate phenotypes study. | Narayanan B et al. | β | 2014 | β |
| Restless legs symptoms in adolescents: epidemiology, heritability, and pubertal effects. | Zhang J et al. | β | 2014 | β |
| Shared genetic factors influence risk for bipolar disorder and alcohol use disorders. | Carmiol N et al. | β | 2014 | β |
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| The heritability of abortion in pedigree Charollais flocks. | Darlay R et al. | β | 2014 | β |
| Treatment responses to tooth whitening in twins. | Corby PM et al. | β | 2014 | β |
| Unveiling the mysteries of the genetics of osteoporosis. | Alonso N et al. | β | 2014 | β |
| Utility of large consanguineous family-based model for investigating the genetics of type 2 diabetes mellitus. | Al-Sinani S et al. | β | 2014 | β |
| Volumetric mammographic density: heritability and association with breast cancer susceptibility loci. | Brand JS et al. | β | 2014 | β |
| A comprehensive analysis of adiponectin QTLs using SNP association, SNP cis-effects on peripheral blood gene expression and gene expression correlation identified novel metabolic syndrome (MetS) genes with potential role in carcinogenesis and systemic inflammation. | Zhang Y et al. | β | 2013 | β |
| A genome-wide association study of the human metabolome in a community-based cohort. | Rhee EP et al. | β | 2013 | β |
| A genome-wide integrative genomic study localizes genetic factors influencing antibodies against Epstein-Barr virus nuclear antigen 1 (EBNA-1). | Rubicz R et al. | β | 2013 | β |
| A genome-wide search for type 2 diabetes susceptibility genes in an extended Arab family. | Al Safar HS et al. | β | 2013 | β |
| A kernel of truth: statistical advances in polygenic variance component models for complex human pedigrees. | Blangero J et al. | β | 2013 | β |
| Association mapping of the high-grade myopia MYP3 locus reveals novel candidates UHRF1BP1L, PTPRR, and PPFIA2. | Hawthorne F et al. | β | 2013 | β |
| Association of adiponectin promoter variants with traits and clusters of metabolic syndrome in Arabs: family-based study. | Zadjali F et al. | β | 2013 | β |
| Association of dopamine transporter gene variants with childhood ADHD features in bipolar disorder. | Greenwood TA et al. | β | 2013 | β |
| Association of functional polymorphism rs2231142 (Q141K) in the ABCG2 gene with serum uric acid and gout in 4 US populations: the PAGE Study. | Zhang L et al. | β | 2013 | β |
| A variant in the LRRFIP1 gene is associated with adiposity and inflammation. | Plourde M et al. | β | 2013 | β |
| Characterization of European ancestry nonalcoholic fatty liver disease-associated variants in individuals of African and Hispanic descent. | Palmer ND et al. | β | 2013 | β |
| Characterization of the infant BMI peak: sex differences, birth year cohort effects, association with concurrent adiposity, and heritability. | Johnson W et al. | β | 2013 | β |
| Circulating CD34(+) progenitor cell frequency is associated with clinical and genetic factors. | Cohen KS et al. | β | 2013 | β |
| Clustering tooth surfaces into biologically informative caries outcomes. | Shaffer JR et al. | β | 2013 | β |
| Common genetic variation at the IL1RL1 locus regulates IL-33/ST2 signaling. | Ho JE et al. | β | 2013 | β |
| Complex variation in measures of general intelligence and cognitive change. | Rowe SJ et al. | β | 2013 | β |
| Correcting for population structure and kinship using the linear mixed model: theory and extensions. | Hoffman GE | β | 2013 | β |
| CRHR1 genotypes, neural circuits and the diathesis for anxiety and depression. | Rogers J et al. | β | 2013 | β |
| Decreased bone mineral density in subjects carrying familial defective apolipoprotein B-100. | Yerges-Armstrong LM et al. | β | 2013 | β |
| Demographic, socioeconomic, and behavioral factors affecting patterns of tooth decay in the permanent dentition: principal components and factor analyses. | Shaffer JR et al. | β | 2013 | β |
| Detection and impact of rare regulatory variants in human disease. | Li X et al. | β | 2013 | β |
| Diffusion tensor imaging white matter endophenotypes in patients with schizophrenia or psychotic bipolar disorder and their relatives. | Skudlarski P et al. | β | 2013 | β |
| Dynamic genetic linkage of intermediate blood pressure phenotypes during postural adaptations in a founder population. | Arenas IA et al. | β | 2013 | β |
| Employing MCMC under the PPL framework to analyze sequence data in large pedigrees. | Huang Y et al. | β | 2013 | β |
| Environmental and genetic contribution to hypertension prevalence: data from an epidemiological survey on Sardinian genetic isolates. | Biino G et al. | β | 2013 | β |
| Epidemiology and genetic determinants of progressive deterioration of glycaemia in American Indians: the Strong Heart Family Study. | Franceschini N et al. | β | 2013 | β |
| Estimating the contributions of rare and common genetic variations and clinical measures to a model trait: adiponectin. | An SS et al. | β | 2013 | β |
| Evidence for a genetic link between bone and vascular measures in African ancestry families. | Kuipers AL et al. | β | 2013 | β |
| Evidence for novel genetic loci associated with metabolic traits in Yup'ik people. | Aslibekyan S et al. | β | 2013 | β |
| Examination of rare missense variants in the CHRNA5-A3-B4 gene cluster to level of response to alcohol in the San Diego Sibling Pair study. | Choquet H et al. | β | 2013 | β |
| Factors related to fungiform papillae density: the beaver dam offspring study. | Fischer ME et al. | β | 2013 | β |
| Familial aggregation of circulating C-reactive protein in polycystic ovary syndrome. | Sasidevi A et al. | β | 2013 | β |
| Fatty acid binding protein 3 (fabp3) is associated with insulin, lipids and cardiovascular phenotypes of the metabolic syndrome through epigenetic modifications in a Northern European family population. | Zhang Y et al. | β | 2013 | β |
| Genetic analysis of adiponectin variation and its association with type 2 diabetes in African Americans. | Sandy An S et al. | β | 2013 | β |
| Genetic analysis of a rat model of aerobic capacity and metabolic fitness. | Ren YY et al. | β | 2013 | β |
| Genetic and environmental associations between C-reactive protein and components of the metabolic syndrome. | Lee K et al. | β | 2013 | β |
| Genetic architecture of carotid artery intima-media thickness in Mexican Americans. | Melton PE et al. | β | 2013 | β |
| Genetic basis for the increased expression of vacuolar H+ translocating ATPase genes upon imatinib treatment in human lymphoblastoid cells. | Kulkarni H et al. | β | 2013 | β |
| Genetic determinants of plasma Ξ²β-glycoprotein I levels: a genome-wide association study in extended pedigrees from Spain. | Athanasiadis G et al. | β | 2013 | β |
| Genetic dissection of the pre-eclampsia susceptibility locus on chromosome 2q22 reveals shared novel risk factors for cardiovascular disease. | Johnson MP et al. | β | 2013 | β |
| Genetic effects on DNA methylation and its potential relevance for obesity in Mexican Americans. | Carless MA et al. | β | 2013 | β |
| Genetic epidemiology and genome-wide linkage analysis of carotid artery ultrasound traits in multigenerational African ancestry families. | Kuipers AL et al. | β | 2013 | β |
| Genetic epidemiology of cardiometabolic risk factors and their clustering patterns in Mexican American children and adolescents: the SAFARI Study. | Fowler SP et al. | β | 2013 | β |
| Genetic influences on plasma CFH and CFHR1 concentrations and their role in susceptibility to age-related macular degeneration. | Ansari M et al. | β | 2013 | β |
| Genetic origins of social networks in rhesus macaques. | Brent LJ et al. | β | 2013 | β |
| Genetic risk for earlier menarche also influences peripubertal body mass index. | Johnson W et al. | β | 2013 | β |
| Genetics of coronary artery calcification among African Americans, a meta-analysis. | Wojczynski MK et al. | β | 2013 | β |
| Genetic variants associated with protein C levels. | Vossen CY et al. | β | 2013 | β |
| Genetic variation at the delta-sarcoglycan (SGCD) locus elevates heritable sympathetic nerve activity in human twin pairs. | Hightower CM et al. | β | 2013 | β |
| Genome-wide analysis of BMI in adolescents and young adults reveals additional insight into the effects of genetic loci over the life course. | Graff M et al. | β | 2013 | β |
| Genome-wide association analysis confirms and extends the association of SLC2A9 with serum uric acid levels to Mexican Americans. | Voruganti VS et al. | β | 2013 | β |
| Genome wide association and linkage analyses identified three loci-4q25, 17q23.2, and 10q11.21-associated with variation in leukocyte telomere length: the Long Life Family Study. | Lee JH et al. | β | 2013 | β |
| Genome-wide association study of irritable vs. elated mania suggests genetic differences between clinical subtypes of bipolar disorder. | Greenwood TA et al. | β | 2013 | β |
| Genome-wide association study of personality traits in the long life family study. | Bae HT et al. | β | 2013 | β |
| Genome-wide linkage analyses of 12 endophenotypes for schizophrenia from the Consortium on the Genetics of Schizophrenia. | Greenwood TA et al. | β | 2013 | β |
| Genome-wide linkage analysis of cardiovascular disease biomarkers in a large, multigenerational family. | Nolan D et al. | β | 2013 | β |
| Genome-wide linkage analysis of carotid artery lumen diameter: the strong heart family study. | Bella JN et al. | β | 2013 | β |
| Genotype by energy expenditure interaction with metabolic syndrome traits: the Portuguese healthy family study. | Santos DM et al. | β | 2013 | β |
| Heredity and cardiometabolic risk: naturally occurring polymorphisms in the human neuropeptide Y(2) receptor promoter disrupt multiple transcriptional response motifs. | Wei Z et al. | β | 2013 | β |
| Heritabilities of facial measurements and their latent factors in korean families. | Kim HJ et al. | β | 2013 | β |
| Heritability and genome-wide SNP linkage analysis of temperament in bipolar disorder. | Greenwood TA et al. | β | 2013 | β |
| Heritability and linkage analysis of personality in bipolar disorder. | Greenwood TA et al. | β | 2013 | β |
| Heritability and preliminary genome-wide linkage analysis of arsenic metabolites in urine. | Tellez-Plaza M et al. | β | 2013 | β |
| Heritability, genetic correlation and linkage to the 9p21.3 region of mixed platelet-leukocyte conjugates in families with and without early myocardial infarction. | Gianfagna F et al. | β | 2013 | β |
| Heritability of subcortical volumetric traits in mesial temporal lobe epilepsy. | Alhusaini S et al. | β | 2013 | β |
| Heritable influence of DBH on adrenergic and renal function: twin and disease studies. | Pasha DN et al. | β | 2013 | β |
| Identification of antithrombin-modulating genes. Role of LARGE, a gene encoding a bifunctional glycosyltransferase, in the secretion of proteins? | de la Morena-Barrio ME et al. | β | 2013 | β |
| Identification of pleiotropic genetic effects on obesity and brain anatomy. | Curran JE et al. | β | 2013 | β |
| Impact of HDL genetic risk scores on coronary artery calcified plaque and mortality in individuals with type 2 diabetes from the Diabetes Heart Study. | Raffield LM et al. | β | 2013 | β |
| Intracortical bone remodeling variation shows strong genetic effects. | Havill LM et al. | β | 2013 | β |
| Joint linkage and association analysis with exome sequence data implicates SLC25A40 in hypertriglyceridemia. | Rosenthal EA et al. | β | 2013 | β |
| Lack of associations of ten candidate coronary heart disease risk genetic variants and subclinical atherosclerosis in four US populations: the Population Architecture using Genomics and Epidemiology (PAGE) study. | Zhang L et al. | β | 2013 | β |
| Lifetime history of traumatic events in an American Indian community sample: heritability and relation to substance dependence, affective disorder, conduct disorder and PTSD. | Ehlers CL et al. | β | 2013 | β |
| Linkage of type 2 diabetes on chromosome 9p24 in Mexican Americans: additional evidence from the Veterans Administration Genetic Epidemiology Study (VAGES). | Farook VS et al. | β | 2013 | β |
| Localization of a major susceptibility locus influencing preterm birth. | Chittoor G et al. | β | 2013 | β |
| Mapping eQTLs in the Norfolk Island genetic isolate identifies candidate genes for CVD risk traits. | Benton MC et al. | β | 2013 | β |
| Meta-analysis of genome-wide studies identifies MEF2C SNPs associated with bone mineral density at forearm. | Zheng HF et al. | β | 2013 | β |
| Multi-site genetic analysis of diffusion images and voxelwise heritability analysis: a pilot project of the ENIGMA-DTI working group. | Jahanshad N et al. | β | 2013 | β |
| Neurophysiological evidence of corollary discharge function during vocalization in psychotic patients and their nonpsychotic first-degree relatives. | Ford JM et al. | β | 2013 | β |
| Neuropsychological impairments in schizophrenia and psychotic bipolar disorder: findings from the Bipolar-Schizophrenia Network on Intermediate Phenotypes (B-SNIP) study. | Hill SK et al. | β | 2013 | β |
| Nonsyndromic brachydactyly type D and type E mapped to 7p15 in healthy children and adults from the Jirel ethnic group in eastern Nepal. | Williams KD et al. | β | 2013 | β |
| Performance on the Wisconsin Card Sorting Test in families of schizophrenia patients with different familial loadings. | Lin SH et al. | β | 2013 | β |
| Persistent infection with neurotropic herpes viruses and cognitive impairment. | Watson AM et al. | β | 2013 | β |
| Plasma lipidomic profile signature of hypertension in Mexican American families: specific role of diacylglycerols. | Kulkarni H et al. | β | 2013 | β |
| Plasma phosphatidylcholine and sphingomyelin concentrations are associated with depression and anxiety symptoms in a Dutch family-based lipidomics study. | Demirkan A et al. | β | 2013 | β |
| Plasma proprotein convertase subtilisin kexin type 9 levels are related to markers of cholesterol synthesis in familial combined hyperlipidemia. | Brouwers MC et al. | β | 2013 | β |
| Polymorphisms in the Selenoprotein S gene and subclinical cardiovascular disease in the Diabetes Heart Study. | Cox AJ et al. | β | 2013 | β |
| Polymorphisms in the SOCS7 gene and glucose homeostasis traits. | Capuano MM et al. | β | 2013 | β |
| Principal components of heritability from neurocognitive domains differ between families with schizophrenia and control subjects. | Wiener H et al. | β | 2013 | β |
| QTL-based association analyses reveal novel genes influencing pleiotropy of metabolic syndrome (MetS). | Zhang Y et al. | β | 2013 | β |
| QTL mapping of leukocyte telomere length in American Indians: the Strong Heart Family Study. | Zhu Y et al. | β | 2013 | β |
| Quantitative trait locus linkage analysis in a large Amish pedigree identifies novel candidate loci for erythrocyte traits. | Hinckley JD et al. | β | 2013 | β |
| REFINING GENETICALLY INFERRED RELATIONSHIPS USING TREELET COVARIANCE SMOOTHING. | Crossett A et al. | β | 2013 | β |
| Response inhibition and ADHD traits: correlates and heritability in a community sample. | Crosbie J et al. | β | 2013 | β |
| Sequence kernel association test for quantitative traits in family samples. | Chen H et al. | β | 2013 | β |
| Sex differences in familiality effects on neurocognitive performance in schizophrenia. | Calkins ME et al. | β | 2013 | β |
| Sex-specific heritability of spontaneous lipid levels in an extended pedigree of Indian-origin rhesus macaques (Macaca mulatta). | Vinson A et al. | β | 2013 | β |
| Significant genotype by diet (G Γ D) interaction effects on cardiometabolic responses to a pedigree-wide, dietary challenge in vervet monkeys (Chlorocebus aethiops sabaeus). | Voruganti VS et al. | β | 2013 | β |
| Skeletal growth and the changing genetic landscape during childhood and adulthood. | Duren DL et al. | β | 2013 | β |
| SLCO1B1 variants and urine arsenic metabolites in the Strong Heart Family Study. | Gribble MO et al. | β | 2013 | β |
| Statistical genetic analysis of serological measures of common, chronic infections in Alaska Native participants in the GOCADAN study. | Rubicz R et al. | β | 2013 | β |
| Sulcal depth-position profile is a genetically mediated neuroscientific trait: description and characterization in the central sulcus. | McKay DR et al. | β | 2013 | β |
| The ABCG8 G574R variant, serum plant sterol levels, and cardiovascular disease risk in the Old Order Amish. | Horenstein RB et al. | β | 2013 | β |
| The association between renal function biomarkers and subclinical cardiovascular measures in African Caribbean families. | Li H et al. | β | 2013 | β |
| The contribution of diet and genotype to iron status in women: a classical twin study. | Fairweather-Tait SJ et al. | β | 2013 | β |
| The CYP2C19*17 variant is not independently associated with clopidogrel response. | Lewis JP et al. | β | 2013 | β |
| The heritability of glaucoma-related traits corneal hysteresis, central corneal thickness, intraocular pressure, and choroidal blood flow pulsatility. | Freeman EE et al. | β | 2013 | β |
| The positive association of obesity variants with adulthood adiposity strengthens over an 80-year period: a gene-by-birth year interaction. | Demerath EW et al. | β | 2013 | β |
| Transferability and fine mapping of type 2 diabetes loci in African Americans: the Candidate Gene Association Resource Plus Study. | Ng MC et al. | β | 2013 | β |
| Urotensin-II system in genetic control of blood pressure and renal function. | Debiec R et al. | β | 2013 | β |
| Utilizing extended pedigree information for discovery and confirmation of copy number variable regions among Mexican Americans. | Blackburn A et al. | β | 2013 | β |
| Variability in associations of phosphatidylcholine molecular species with metabolic syndrome in Mexican-American families. | Kulkarni H et al. | β | 2013 | β |
| Variants in adiponectin signaling pathway genes show little association with subclinical CVD in the diabetes heart study. | Cox AJ et al. | β | 2013 | β |
| Waist circumference independently associates with the risk of insulin resistance and type 2 diabetes in mexican american families. | Mamtani M et al. | β | 2013 | β |
| 25(OH)D3 and cardiovascular risk factors in female nonhuman primates. | Jorgensen MJ et al. | β | 2012 | β |
| Accounting for a quantitative trait locus for plasma triglyceride levels: utilization of variants in multiple genes. | Martin LJ et al. | β | 2012 | β |
| A genome-wide analysis of 'Bounty' descendants implicates several novel variants in migraine susceptibility. | Cox HC et al. | β | 2012 | β |
| A genome-wide association search for type 2 diabetes genes in African Americans. | Palmer ND et al. | β | 2012 | β |
| A genome-wide linkage study of individuals with high scores on NEO personality traits. | Amin N et al. | β | 2012 | β |
| A genome-wide scan for quantitative trait loci affecting respiratory disease and immune capacity in Landrace pigs. | Okamura T et al. | β | 2012 | β |
| Aging does not reduce heat shock protein 70 in the absence of chronic insulin resistance. | Kavanagh K et al. | β | 2012 | β |
| An international collaborative family-based whole genome quantitative trait linkage scan for myopic refractive error. | Abbott D et al. | β | 2012 | β |
| A non-human primate system for large-scale genetic studies of complex traits. | Jasinska AJ et al. | β | 2012 | β |
| An X chromosome association scan of the Norfolk Island genetic isolate provides evidence for a novel migraine susceptibility locus at Xq12. | Maher BH et al. | β | 2012 | β |
| Apoptosis-inducing factor is involved in gentamicin-induced vestibular hair cell death. | Zhang D et al. | β | 2012 | β |
| A shared low-frequency oscillatory rhythm abnormality in resting and sensory gating in schizophrenia. | Hong LE et al. | β | 2012 | β |
| Association among obesity-related anthropometric phenotypes: analyzing genetic and environmental contribution. | Jelenkovic A et al. | β | 2012 | β |
| Association between ADIPOQ SNPs with plasma adiponectin and glucose homeostasis and adiposity phenotypes in the IRAS Family Study. | An SS et al. | β | 2012 | β |
| Association of differential gene expression with imatinib mesylate and omacetaxine mepesuccinate toxicity in lymphoblastoid cell lines. | Kulkarni H et al. | β | 2012 | β |
| Autonomic and hemodynamic origins of pre-hypertension: central role of heredity. | Davis JT et al. | β | 2012 | β |
| Autosomal dominant Parkinson's disease in a large German pedigree. | BrΓΌggemann N et al. | β | 2012 | β |
| Body composition and metabolic parameters are associated with variation in thyroid hormone levels among euthyroid young men. | Roef G et al. | β | 2012 | β |
| Clinical and genetic correlates of growth differentiation factor 15 in the community. | Ho JE et al. | β | 2012 | β |
| Collection of clinical and epidemiological data for genetic linkage and association studies. | Farrer L et al. | β | 2012 | β |
| Comparison of requirements and capabilities of major multipurpose software packages. | Igo RP et al. | β | 2012 | β |
| Comprehensive genomic analyses associate UGT8 variants with musical ability in a Mongolian population. | Park H et al. | β | 2012 | β |
| Computationally efficient multipoint linkage analysis on extended pedigrees for trait models with two contributing major Loci. | Su M et al. | β | 2012 | β |
| Current knowledge of the genetics of otitis media. | HafrΓ©n L et al. | β | 2012 | β |
| Detection of a quantitative trait locus associated with resistance to Ascaris suum infection in pigs. | Skallerup P et al. | β | 2012 | β |
| Detection of identity by descent using next-generation whole genome sequencing data. | Su SY et al. | β | 2012 | β |
| Differences in arachidonic acid levels and fatty acid desaturase (FADS) gene variants in African Americans and European Americans with diabetes or the metabolic syndrome. | Sergeant S et al. | β | 2012 | β |
| Differential coexpression analysis of obesity-associated networks in human subcutaneous adipose tissue. | Walley AJ et al. | β | 2012 | β |
| Epidemiologic characteristics of intraocular pressure in the Korean and Mongolian populations: the Healthy Twin and the GENDISCAN study. | Lee MK et al. | β | 2012 | β |
| Evaluation of a bayesian model integration-based method for censored data. | Hou L et al. | β | 2012 | β |
| Evaluation of record linkage between a large healthcare provider and the Utah Population Database. | DuVall SL et al. | β | 2012 | β |
| Event-related oscillations to affective stimuli: heritability, linkage and relationship to externalizing disorders. | Criado JR et al. | β | 2012 | β |
| Exome sequencing identifies 2 rare variants for low high-density lipoprotein cholesterol in an extended family. | Reddy MV et al. | β | 2012 | β |
| Exploring differences in adiposity in two U.S. Hispanic populations of Mexican origin using social, behavioral, physiologic and genetic markers: the IRAS Family Study. | Young KA et al. | β | 2012 | β |
| Familial aggregation and heritability of insomnia in a community-based study. | Wing YK et al. | β | 2012 | β |
| Fine mapping of porcine SSC14 QTL and SCD gene effects on fatty acid composition and melting point of fat in a Duroc purebred population. | Uemoto Y et al. | β | 2012 | β |
| Fine mapping study reveals novel candidate genes for carotid intima-media thickness in Dominican Republican families. | Wang L et al. | β | 2012 | β |
| Follow-up association study of linkage regions reveals multiple candidate genes for carotid plaque in Dominicans. | Dong C et al. | β | 2012 | β |
| Gene Γ gene interaction in shared etiology of autism and specific language impairment. | Bartlett CW et al. | β | 2012 | β |
| Gene mapping study for constitutive skin color in an isolated Mongolian population. | Paik SH et al. | β | 2012 | β |
| Genetic analyses of smoking initiation, persistence, quantity, and age-at-onset of regular cigarette use in Brazilian families: the Baependi Heart Study. | Horimoto AR et al. | β | 2012 | β |
| Genetic analysis of serum osteocalcin and bone mineral in multigenerational Afro-Caribbean families. | Kuipers AL et al. | β | 2012 | β |
| Genetic and environmental factors influencing the Placental Growth Factor (PGF) variation in two populations. | Sorice R et al. | β | 2012 | β |
| Genetic associations between neuregulin-1 SNPs and neurocognitive function in multigenerational, multiplex schizophrenia families. | Yokley JL et al. | β | 2012 | β |
| Genetic contributions to the midsagittal area of the corpus callosum. | Phillips KA et al. | β | 2012 | β |
| Genetic determinants of 5-lipoxygenase pathway in a Spanish population and their relationship with cardiovascular risk. | Camacho M et al. | β | 2012 | β |
| Genetic mapping of habitual substance use, obesity-related traits, responses to mental and physical stress, and heart rate and blood pressure measurements reveals shared genes that are overrepresented in the neural synapse. | Nikpay M et al. | β | 2012 | β |
| Genetic modifiers of nutritional status in cystic fibrosis. | Bradley GM et al. | β | 2012 | β |
| Genetic structure of personality factors and bipolar disorder in families segregating bipolar disorder. | Hare E et al. | β | 2012 | β |
| Genetic susceptibility to dental caries on pit and fissure and smooth surfaces. | Shaffer JR et al. | β | 2012 | β |
| Genetic variants in SCN5A promoter are associated with arrhythmia phenotype severity in patients with heterozygous loss-of-function mutation. | Park JK et al. | β | 2012 | β |
| Genetic variation in SH3-domain GRB2-like (endophilin)-interacting protein 1 has a major impact on fat mass. | Cummings N et al. | β | 2012 | β |
| Genetic variation within a metabolic motif in the chromogranin a promoter: pleiotropic influence on cardiometabolic risk traits in twins. | Rao F et al. | β | 2012 | β |
| Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. | Fox CS et al. | β | 2012 | β |
| Genome-wide association of BMI in African Americans. | Ng MC et al. | β | 2012 | β |
| Genome-wide association of pericardial fat identifies a unique locus for ectopic fat. | Fox CS et al. | β | 2012 | β |
| Genome-wide association replicates the association of Duffy antigen receptor for chemokines (DARC) polymorphisms with serum monocyte chemoattractant protein-1 (MCP-1) levels in Hispanic children. | Voruganti VS et al. | β | 2012 | β |
| Genome-wide association study identifies novel loci association with fasting insulin and insulin resistance in African Americans. | Chen G et al. | β | 2012 | β |
| Genome-wide linkage and positional association study of blood pressure response to dietary sodium intervention: the GenSalt Study. | Mei H et al. | β | 2012 | β |
| Genome-wide linkage scan for quantitative trait loci underlying normal variation in heel bone ultrasound measures. | Lee M et al. | β | 2012 | β |
| Genome-wide linkage scan of antisocial behavior, depression, and impulsive substance use in the UCSF family alcoholism study. | Gizer IR et al. | β | 2012 | β |
| Genome-wide mapping for fatty acid composition and melting point of fat in a purebred Duroc pig population. | Uemoto Y et al. | β | 2012 | β |
| GenotypeΓage interaction in human transcriptional ageing. | Kent JW et al. | β | 2012 | β |
| GLOGS: a fast and powerful method for GWAS of binary traits with risk covariates in related populations. | Stanhope SA et al. | β | 2012 | β |
| Heritability analysis suggests comparable genetic component of mechanical pain threshold and tolerance. | MiljkoviΔ A et al. | β | 2012 | β |
| Heritability and genetic correlations of obesity-related phenotypes among Roma people. | Poveda A et al. | β | 2012 | β |
| Heritability and genome-wide linkage analysis of migraine in the genetic isolate of Norfolk Island. | Cox HC et al. | β | 2012 | β |
| Heritability of chronic pain in 2195 extended families. | Hocking LJ et al. | β | 2012 | β |
| Heritability of functioning in families with schizophrenia in relation to neurocognition. | Savage RM et al. | β | 2012 | β |
| Heritability of multivariate gray matter measures in schizophrenia. | Turner JA et al. | β | 2012 | β |
| Heritability of prevalent vertebral fracture and volumetric bone mineral density and geometry at the lumbar spine in three generations of the Framingham study. | Liu CT et al. | β | 2012 | β |
| Heritability of serum sodium concentration: evidence for sex- and ethnic-specific effects. | Wilmot B et al. | β | 2012 | β |
| Heritability variations of body linearity and obesity indicators during growth. | Poveda A et al. | β | 2012 | β |
| Heritable patterns of tooth decay in the permanent dentition: principal components and factor analyses. | Shaffer JR et al. | β | 2012 | β |
| High dimensional endophenotype ranking in the search for major depression risk genes. | Glahn DC et al. | β | 2012 | β |
| Host genetics and population structure effects on parasitic disease. | Williams-Blangero S et al. | β | 2012 | β |
| Identification of common variants associated with human hippocampal and intracranial volumes. | Stein JL et al. | β | 2012 | β |
| Improved methods to identify stable, highly heritable subtypes of opioid use and related behaviors. | Sun J et al. | β | 2012 | β |
| Influence of age, gender and lifestyle in lymphocyte subsets: report from the Spanish Gait-2 Study. | GarcΓa-Dabrio MC et al. | β | 2012 | β |
| Insomnia, sleep quality, pain, and somatic symptoms: sex differences and shared genetic components. | Zhang J et al. | β | 2012 | β |
| Insulin clearance: confirmation as a highly heritable trait, and genome-wide linkage analysis. | Guo X et al. | β | 2012 | β |
| Lexical decision as an endophenotype for reading comprehension: an exploration of an association. | Naples A et al. | β | 2012 | β |
| Linkage analysis for plasma amyloid beta levels in persons with hypertension implicates AΞ²-40 levels to presenilin 2. | Ibrahim-Verbaas CA et al. | β | 2012 | β |
| Mapping QTL for fat area ratios and serum leptin concentrations in a Duroc purebred population. | Uemoto Y et al. | β | 2012 | β |
| Maternal and offspring dopamine D4 receptor genotypes interact to influence juvenile impulsivity in vervet monkeys. | Fairbanks LA et al. | β | 2012 | β |
| Metabolic syndrome is linked to chromosome 7q21 and associated with genetic variants in CD36 and GNAT3 in Mexican Americans. | Farook VS et al. | β | 2012 | β |
| Mismatch negativity and low frequency oscillations in schizophrenia families. | Hong LE et al. | β | 2012 | β |
| Model-free linkage analysis of a quantitative trait. | Morris NJ et al. | β | 2012 | β |
| Model-free tests for genetic linkage. | Amos CI et al. | β | 2012 | β |
| Novel associations of nonstructural Loci with paraoxonase activity. | Quillen EE et al. | β | 2012 | β |
| Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. | Comuzzie AG et al. | β | 2012 | β |
| Parameter estimation and quantitative parametric linkage analysis with GENEHUNTER-QMOD. | KΓΌnzel T et al. | β | 2012 | β |
| Plasma levels of antibodies against oxidized LDL are inherited but not associated with HDL-cholesterol level in families with early coronary heart disease. | Paavola T et al. | β | 2012 | β |
| Polymorphisms in sh2b1 and spns1 loci are associated with triglyceride levels in a healthy population in northern Sweden. | VΓ€stermark Γ et al. | β | 2012 | β |
| P-selectin Expression Tracks Cerebral Atrophy in Mexican-Americans. | Kochunov P et al. | β | 2012 | β |
| QTL affecting stress response to crowding in a rainbow trout broodstock population. | Rexroad CE et al. | β | 2012 | β |
| RNA-Seq identifies SNP markers for growth traits in rainbow trout. | Salem M et al. | β | 2012 | β |
| Semiparametric variance components models for genetic studies with longitudinal phenotypes. | Wang Y et al. | β | 2012 | β |
| Serum resistin and kidney function: a family-based study in non-diabetic, untreated individuals. | Menzaghi C et al. | β | 2012 | β |
| Sex-specific regulation of mitochondrial DNA levels: genome-wide linkage analysis to identify quantitative trait loci. | LΓ³pez S et al. | β | 2012 | β |
| SNP set association analysis for familial data. | Schifano ED et al. | β | 2012 | β |
| Systems genetics of the nuclear factor-ΞΊB signal transduction network. I. Detection of several quantitative trait loci potentially relevant to aging. | Diego VP et al. | β | 2012 | β |
| The association between fat and lean mass and bone mineral density: the Healthy Twin Study. | Park JH et al. | β | 2012 | β |
| The heritability of mammographic breast density and circulating sex-hormone levels: two independent breast cancer risk factors. | Varghese JS et al. | β | 2012 | β |
| The nature of schizotypy among multigenerational multiplex schizophrenia families. | Tarbox SI et al. | β | 2012 | β |
| The prothrombotic phenotypes in familial protein C deficiency are differentiated by computational modeling of thrombin generation. | Brummel-Ziedins KE et al. | β | 2012 | β |
| The search for longevity and healthy aging genes: insights from epidemiological studies and samples of long-lived individuals. | Murabito JM et al. | β | 2012 | β |
| UGT1A1 is a major locus influencing bilirubin levels in African Americans. | Chen G et al. | β | 2012 | β |
| Variability in the heritability of body mass index: a systematic review and meta-regression. | Elks CE et al. | β | 2012 | β |
| Variants in CPT1A, FADS1, and FADS2 are Associated with Higher Levels of Estimated Plasma and Erythrocyte Delta-5 Desaturases in Alaskan Eskimos. | Voruganti VS et al. | β | 2012 | β |
| Varying coefficient models for mapping quantitative trait loci using recombinant inbred intercrosses. | Gong Y et al. | β | 2012 | β |
| Aberrant glycosylation of IgA1 is inherited in both pediatric IgA nephropathy and Henoch-SchΓΆnlein purpura nephritis. | Kiryluk K et al. | β | 2011 | β |
| A comparison of strategies for analyzing dichotomous outcomes in genome-wide association studies with general pedigrees. | Chen MH et al. | β | 2011 | β |
| ADHD in Dutch adults: heritability and linkage study. | Saviouk V et al. | β | 2011 | β |
| A functional XPNPEP2 promoter haplotype leads to reduced plasma aminopeptidase P and increased risk of ACE inhibitor-induced angioedema. | Cilia La Corte AL et al. | β | 2011 | β |
| A genome-wide association study of the Protein C anticoagulant pathway. | Athanasiadis G et al. | β | 2011 | β |
| A genome-wide linkage scan for quantitative trait loci influencing the craniofacial complex in humans (Homo sapiens sapiens). | Sherwood RJ et al. | β | 2011 | β |
| A genome-wide linkage study of mammographic density, a risk factor for breast cancer. | Greenwood CM et al. | β | 2011 | β |
| Analysis of 94 candidate genes and 12 endophenotypes for schizophrenia from the Consortium on the Genetics of Schizophrenia. | Greenwood TA et al. | β | 2011 | β |
| Anatomic brain asymmetry in vervet monkeys. | Fears SC et al. | β | 2011 | β |
| Aorta Measurements are Heritable and Influenced by Bicuspid Aortic Valve. | Martin LJ et al. | β | 2011 | β |
| A QTL for genotype by sex interaction for anthropometric measurements in Alaskan Eskimos (GOCADAN Study) on chromosome 19q12-13. | Voruganti VS et al. | β | 2011 | β |
| Association between SLC20A1 and sodium-lithium countertransport. | Zheng X et al. | β | 2011 | β |
| Association of PNPLA3 with non-alcoholic fatty liver disease in a minority cohort: the Insulin Resistance Atherosclerosis Family Study. | Wagenknecht LE et al. | β | 2011 | β |
| Circulating testosterone and SHBG concentrations are heritable in women: the Framingham Heart Study. | Coviello AD et al. | β | 2011 | β |
| Common genetic influences on depression, alcohol, and substance use disorders in Mexican-American families. | Olvera RL et al. | β | 2011 | β |
| Cortical bone health shows significant linkage to chromosomes 2p, 3p, and 17q in 10-year-old children. | Duren DL et al. | β | 2011 | β |
| Detecting pleiotropy and epistasis using variance components linkage analysis in jPAP. | Hasstedt SJ et al. | β | 2011 | β |
| Determinants of blood pressure response to low-salt intake in a healthy adult population. | Montasser ME et al. | β | 2011 | β |
| Differences in the heritability of growth and growth velocity during infancy and associations with FTO variants. | Choh AC et al. | β | 2011 | β |
| Different approaches for dealing with rare variants in family-based genetic studies: application of a Genetic Analysis Workshop 17 problem. | Alfonso de Almeida MA et al. | β | 2011 | β |
| Do rare variant genotypes predict common variant genotypes? | Kent JW et al. | β | 2011 | β |
| Empirically derived subtypes of opioid use and related behaviors. | Chan G et al. | β | 2011 | β |
| Environmental stress alters genetic regulation of novelty seeking in vervet monkeys. | Fairbanks LA et al. | β | 2011 | β |
| Familial concordance for age at natural menopause: results from the Breakthrough Generations Study. | Morris DH et al. | β | 2011 | β |
| Four genetic loci influencing electrocardiographic indices of left ventricular hypertrophy. | Shah S et al. | β | 2011 | β |
| Frailty models: Applications to biomedical and genetic studies. | Govindarajulu US et al. | β | 2011 | β |
| Genetical genomics of Th1 and Th2 immune response in a baboon model of atherosclerosis risk factors. | Vinson A et al. | β | 2011 | β |
| Genetic analysis of cortical thickness and fractional anisotropy of water diffusion in the brain. | Kochunov P et al. | β | 2011 | β |
| Genetic and clinical correlates of early-outgrowth colony-forming units. | Shaw SY et al. | β | 2011 | β |
| Genetic factors influence serological measures of common infections. | Rubicz R et al. | β | 2011 | β |
| Genetic loci for blood lipid levels identified by linkage and association analyses in Caribbean Hispanics. | Dong C et al. | β | 2011 | β |
| Genetic mapping of vascular calcified plaque loci on chromosome 16p in European Americans from the diabetes heart study. | Lehtinen AB et al. | β | 2011 | β |
| Genetic signal maximization using environmental regression. | Melton PE et al. | β | 2011 | β |
| Genetics of VEGF serum variation in human isolated populations of cilento: importance of VEGF polymorphisms. | Ruggiero D et al. | β | 2011 | β |
| Genome scan of clot lysis time and its association with thrombosis in a proteinΒ C-deficient kindred. | Meltzer ME et al. | β | 2011 | β |
| Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits. | Speliotes EK et al. | β | 2011 | β |
| Genome-wide association and linkage identify modifier loci of lung disease severity in cystic fibrosis at 11p13 and 20q13.2. | Wright FA et al. | β | 2011 | β |
| Genome-wide linkage analysis of hemodynamic parameters under mental and physical stress in extended Omani Arab pedigrees: the Oman Family Study. | Hassan MO et al. | β | 2011 | β |
| Genome-wide linkage screen for systolic blood pressure in the Veterans Administration Genetic Epidemiology Study (VAGES) of Mexican-Americans and confirmation of a major susceptibility locus on chromosome 6q14.1. | Puppala S et al. | β | 2011 | β |
| Genomewide linkage study of modifiers of LRRK2-related Parkinson's disease. | Latourelle JC et al. | β | 2011 | β |
| Glucuronic acid epimerase is associated with plasma triglyceride and high-density lipoprotein cholesterol levels in Turks. | HodoΔlugil U et al. | β | 2011 | β |
| Habitual sleep/wake patterns in the Old Order Amish: heritability and association with non-genetic factors. | Evans DS et al. | β | 2011 | β |
| Heritability and familiality of type 2 diabetes and related quantitative traits in the Botnia Study. | Almgren P et al. | β | 2011 | β |
| Heritability and genetic correlation of hair cortisol in vervet monkeys in low and higher stress environments. | Fairbanks LA et al. | β | 2011 | β |
| Heritability Estimation using Regression Models for Correlation. | Lee HS et al. | β | 2011 | β |
| Heritability of ocular component dimensions in mice phenotyped using depth-enhanced swept source optical coherence tomography. | Wang L et al. | β | 2011 | β |
| Heritability of physical activity traits in Brazilian families: the Baependi Heart Study. | Horimoto AR et al. | β | 2011 | β |
| Heritability of serum osteoprotegerin. | Kwan JS et al. | β | 2011 | β |
| High throughput isolation and glycosylation analysis of IgG-variability and heritability of the IgG glycome in three isolated human populations. | PuciΔ M et al. | β | 2011 | β |
| Hypertrophy-associated polymorphisms ascertained in a founder cohort applied to heart failure risk and mortality. | Parsa A et al. | β | 2011 | β |
| Identification of ACOX2 as a shared genetic risk factor for preeclampsia and cardiovascular disease. | Johansson A et al. | β | 2011 | β |
| Identification of genetic loci underlying the phenotypic constructs of autism spectrum disorders. | Liu XQ et al. | β | 2011 | β |
| Identity by descent estimation with dense genome-wide genotype data. | Han L et al. | β | 2011 | β |
| Impact of DISC1 variation on neuroanatomical and neurocognitive phenotypes. | Carless MA et al. | β | 2011 | β |
| Incorporating linkage information into a common disease/rare variant framework. | Hinrichs AL et al. | β | 2011 | β |
| Increased endoplasmic reticulum stress in decidual tissue from pregnancies complicated by fetal growth restriction with and without pre-eclampsia. | Lian IA et al. | β | 2011 | β |
| Large-scale candidate gene analysis of HDL particle features. | Kaess BM et al. | β | 2011 | β |
| Linkage analyses of stimulant dependence, craving, and heavy use in American Indians. | Ehlers CL et al. | β | 2011 | β |
| Linkage analysis merging replicate phenotypes: an application to three quantitative phenotypes in two African samples. | Hinrichs AL et al. | β | 2011 | β |
| Linkage analysis without defined pedigrees. | Day-Williams AG et al. | β | 2011 | β |
| Linkage and association of phospholipid transfer protein activity to LASS4. | Rosenthal EA et al. | β | 2011 | β |
| Linkage and association scan for tanning ability in an isolated Mongolian population. | Paik SH et al. | β | 2011 | β |
| Markers of inflammation are heritable and associated with subcutaneous and ectopic skeletal muscle adiposity in African ancestry families. | Miljkovic I et al. | β | 2011 | β |
| Naturally occurring variations in the human cholinesterase genes: heritability and association with cardiovascular and metabolic traits. | Valle AM et al. | β | 2011 | β |
| Persistent Staphylococcus aureus colonization is not a strongly heritable trait in Amish families. | Roghmann MC et al. | β | 2011 | β |
| Plasma proprotein convertase subtilisin kexin typeΒ 9 is a heritable trait of familial combined hyperlipidaemia. | Brouwers MC et al. | β | 2011 | β |
| Population-based and family-based designs to analyze rare variants in complex diseases. | Kazma R et al. | β | 2011 | β |
| Pre-treatment choroidal thickness is not predictive of susceptibility to form-deprivation myopia in chickens. | Guggenheim JA et al. | β | 2011 | β |
| Quantitative genetics of human morphology and obesity-related phenotypes in nuclear families from the Greater Bilbao (Spain): comparison with other populations. | Jelenkovic A et al. | β | 2011 | β |
| Relationship between ADIPOQ gene, circulating high molecular weight adiponectin and albuminuria in individuals with normal kidney function: evidence from a family-based study. | Menzaghi C et al. | β | 2011 | β |
| Resequencing of IRS2 reveals rare variants for obesity but not fasting glucose homeostasis in Hispanic children. | Butte NF et al. | β | 2011 | β |
| RGS6 variants are associated with dietary fat intake in Hispanics: the IRAS Family Study. | Sibbel SP et al. | β | 2011 | β |
| Seroprevalence of 13 common pathogens in a rapidly growing U.S. minority population: Mexican Americans from San Antonio, TX. | Rubicz R et al. | β | 2011 | β |
| Shared genetic architecture in the relationship between adult stature and subclinical coronary artery atherosclerosis. | Cassidy-Bushrow AE et al. | β | 2011 | β |
| Shared genetic contributions of fruit and vegetable consumption with BMI in families 20 y after sharing a household. | Martin LJ et al. | β | 2011 | β |
| Single-nucleotide polymorphisms in the TNF gene are associated with obesity-related phenotypes in vervet monkeys. | Gray SB et al. | β | 2011 | β |
| "Statistics 101"--a primer for the genetics of complex human disease. | Sinsheimer J | β | 2011 | β |
| Successful identification of rare variants using oligogenic segregation analysis as a prioritizing tool for whole-exome sequencing studies. | Gagnon F et al. | β | 2011 | β |
| The epithelial sodium channel Ξ³-subunit gene and blood pressure: family based association, renal gene expression, and physiological analyses. | BΓΌsst CJ et al. | β | 2011 | β |
| The relationship between bone mineral density and mammographic density in Korean women: the Healthy Twin study. | Sung J et al. | β | 2011 | β |
| Unifying ideas for non-parametric linkage analysis. | Day-Williams AG et al. | β | 2011 | β |
| Using linkage analysis of large pedigrees to guide association analyses. | Choi SH et al. | β | 2011 | β |
| Variants at the endocannabinoid receptor CB1 gene (CNR1) and insulin sensitivity, type 2 diabetes, and coronary heart disease. | de Miguel-Yanes JM et al. | β | 2011 | β |
| Variants in the human potassium channel gene (KCNN3) are associated with migraine in a high risk genetic isolate. | Cox HC et al. | β | 2011 | β |
| Wide disparity in genetic admixture among Mexican Americans from San Antonio, TX. | Beuten J et al. | β | 2011 | β |