The NSW brain tissue resource centre: Banking for alcohol and major neuropsychiatric disorders research.
- Authors
- Sutherland, G T; Sheedy, D; Stevens, J; McCrossin, T; Smith, C C; van Roijen, M; Kril, J J
- Year
- 2016
- Journal
- Alcohol (Fayetteville, N.Y.)
- PMID
- 27139235
- DOI
- 10.1016/j.alcohol.2016.02.005
- PMCID
- PMC4855871
The New South Wales Brain Tissue Resource Centre (NSWBTRC) at the University of Sydney (Australia) is an established human brain bank providing tissue to the neuroscience research community for investigations on alcohol-related brain damage and major psychiatric illnesses such as schizophrenia. The NSWBTRC relies on wide community engagement to encourage those with and without neuropsychiatric illness to consent to donation through its allied research programs. The subsequent provision of high-quality samples relies on standardized operational protocols, associated clinical data, quality control measures, integrated information systems, robust infrastructure, and governance. These processes are continually augmented to complement the changes in internal and external governance as well as the complexity and diversity of advanced investigation techniques. This report provides an overview of the dynamic process of brain banking and discusses the challenges of meeting the future needs of researchers, including synchronicity with other disease-focus collections.
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| Effects of chronic ethanol consumption on brain GLP-1R gene expression in mice and humans. | Torregrosa AB et al. | — | 2026 | → |
| Integrative Genomics Approach Identifies Glial Transcriptomic Dysregulation and Risk in the Cortex of Individuals With Alcohol Use Disorder. | Warden AS et al. | — | 2026 | → |
| Optimization of Brain Tissue Preservation for Nucleic Acid Stability. | Novelli M et al. | — | 2026 | → |
| Quantification of the neuropathology of alcohol use disorder using tissue microarrays. | Liu J et al. | — | 2026 | → |
| A Survey of Community Perceptions on Brain Donation for Research. | Sweeney A et al. | — | 2025 | → |
| Integrated single-cell multiomic profiling of caudate nucleus suggests key mechanisms in alcohol use disorder. | Green NC et al. | — | 2025 | → |
| Quantification of Alzheimer disease neuropathology using tissue microarrays. | Nguyen-Hao HT et al. | — | 2025 | → |
| Validation of <i>GDAP1</i> and <i>HECW2</i> as Epigenetic Markers of Alcohol Use Disorder in Blood and Brain. | Wiegand A et al. | — | 2025 | → |
| Double Chromogen-based Immunohistochemical Staining: An Efficient Approach for Utilizing Long-term Formalin-fixed Tissue in Biobanks. | Maskey D et al. | — | 2024 | → |
| The Experts Speak: Challenges in Banking Brain Tissue for Research. | Rush A et al. | — | 2024 | → |
| Brain proteomic atlas of alcohol use disorder in adult males. | Teng PN et al. | — | 2023 | → |
| A closer look at alcohol-induced changes in the ghrelin system: novel insights from preclinical and clinical data. | Deschaine SL et al. | — | 2022 | → |
| A qualitative study exploring the process of postmortem brain tissue donation after suicide. | Padoan CS et al. | — | 2022 | → |
| Lipidome changes in alcohol-related brain damage. | Smith CC et al. | — | 2022 | → |
| The Amygdala Noradrenergic System Is Compromised With Alcohol Use Disorder. | Varodayan FP et al. | — | 2022 | → |
| The ethical and legal landscape of brain data governance. | Ochang P et al. | — | 2022 | → |
| The glucagon-like peptide-1 system is modulated by acute and chronic alcohol exposure: Findings from human laboratory experiments and a post-mortem brain study. | Farokhnia M et al. | — | 2022 | → |
| Ground state depletion microscopy as a tool for studying microglia-synapse interactions. | Paasila PJ et al. | — | 2021 | → |
| Increased transcription of TSPO, HDAC2, and HDAC6 in the amygdala of males with alcohol use disorder. | De Carvalho LM et al. | — | 2021 | → |
| Clustering of activated microglia occurs before the formation of dystrophic neurites in the evolution of Aβ plaques in Alzheimer's disease. | Paasila PJ et al. | — | 2020 | → |
| Identifying functionally relevant candidate genes for inflexible ethanol intake in mice and humans using a guilt-by-association approach. | Martins de Carvalho L et al. | — | 2020 | → |
| Pursuing the Mechanisms Underlying Alcohol-Induced Changes in the Ghrelin System: New Insights from Preclinical and Clinical Investigations | Farokhnia M et al. | — | 2020 | — |
| Beyond genome-wide significance: integrative approaches to the interpretation and extension of GWAS findings for alcohol use disorder. | Salvatore JE et al. | — | 2019 | → |
| Normal Aging Brain Collection Amsterdam (NABCA): A comprehensive collection of postmortem high-field imaging, neuropathological and morphometric datasets of non-neurological controls. | Jonkman LE et al. | — | 2019 | → |
| Considerations for optimal use of postmortem human brains for molecular psychiatry: lessons from schizophrenia. | Weickert CS et al. | — | 2018 | → |
| Effect of alcohol use disorder on oxytocin peptide and receptor mRNA expression in human brain: A post-mortem case-control study. | Lee MR et al. | — | 2017 | → |
| Gene expression profiling in the human alcoholic brain. | Warden AS et al. | — | 2017 | → |
| The phospholipid composition of the human entorhinal cortex remains relatively stable over 80 years of adult aging. | Hancock SE et al. | — | 2017 | → |
| Cortical grey matter volume reduction in people with schizophrenia is associated with neuro-inflammation. | Zhang Y et al. | — | 2016 | → |
| The effects of chronic smoking on the pathology of alcohol-related brain damage. | McCorkindale AN et al. | — | 2016 | → |