Behavioral disinhibition and the development of early-onset addiction: common and specific influences.
paper
Cited
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- Authors
- Iacono, William G; Malone, Stephen M; McGue, Matt
- Year
- 2008
- Journal
- Annual review of clinical psychology
- PMID
- 18370620
- DOI
- 10.1146/annurev.clinpsy.4.022007.141157
Research on substance use disorders is often compartmentalized, focused on understanding addiction to one substance or substance class at a time. Although this approach has contributed significantly to knowledge about addictions, early-onset substance use disorders appear to share common etiology with each other and with other disorders, traits, behaviors, and endophenotypes associated with behavioral disinhibition. We propose that a common genetic liability to behavioral disinhibition underlies the co-occurrence of these externalizing attributes. This liability is expressed in part through brain mechanisms related to cognitive control, impulsivity, and sensitivity to reward, all of which are maturing during adolescence. During this important transitional period, problem behaviors emerge, including the initiation of substance use. Exposure to various environmental risks further amplifies the risk associated with the common liability, increasing the likelihood of addiction generally. Specific environmental and genetic factors ultimately contribute to the differentiation among externalizing disorders.
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| Understanding the interplay of individual and social-developmental factors in the progression of substance use and mental health from childhood to adulthood. | Jones TM et al. | β | 2016 | β |
| Vulnerable parenting among mothers with substance abuse in their family of origin: a cross-sectional comparative study of mothers in an infant and toddler program. | TedgΓ₯rd E et al. | β | 2016 | β |
| Abnormal reward functioning across substance use disorders and major depressive disorder: Considering reward as a transdiagnostic mechanism. | Baskin-Sommers AR et al. | β | 2015 | β |
| Adolescents' Neural Processing of Risky Decisions: Effects of Sex and Behavioral Disinhibition. | Crowley TJ et al. | β | 2015 | β |
| Adolescent Substance Use and Comorbid Psychopathology: Emotion Regulation Deficits as a Transdiagnostic Risk Factor. | Shadur JM et al. | β | 2015 | β |
| Affective temperaments and concomitant alcohol use disorders in bipolar disorder. | Singh S et al. | β | 2015 | β |
| Aggression as a Predictor of Early Substance Use Initiation among Youth with Family Histories of Substance Use Disorders. | Mathias CW et al. | β | 2015 | β |
| Altering the Cognitive-Affective Dysfunctions of Psychopathic and Externalizing Offender Subtypes with Cognitive Remediation. | Baskin-Sommers AR et al. | β | 2015 | β |
| Antisocial behavior reduces the association between subdimensions of ADHD symptoms and alcohol use in a large population-based sample of adolescents. | LΓΆvenhag S et al. | β | 2015 | β |
| Application of an alcohol clamp paradigm to examine inhibitory control, subjective responses, and acute tolerance in late adolescence. | Hendershot CS et al. | β | 2015 | β |
| Behavioral Impulsivity and Risk-Taking Trajectories Across Early Adolescence in Youths With and Without Family Histories of Alcohol and Other Drug Use Disorders. | Dougherty DM et al. | β | 2015 | β |
| Biological Risk for the Development of Problem Behavior in Adolescence: Integrating Insights from Behavioral Genetics and Neuroscience. | Harden KP et al. | β | 2015 | β |
| Bridging the gap between the neurocognitive lab and the addiction clinic. | Franken IHA et al. | β | 2015 | β |
| Childhood stress exposure among preadolescents with and without family histories of substance use disorders. | Charles NE et al. | β | 2015 | β |
| Delinquency and association with behavioral disorders and substance abuse. | DΓ³ria GM et al. | β | 2015 | β |
| Drinking patterns of alcohol intoxicated adolescents in the emergency department: A latent class analysis. | Diestelkamp S et al. | β | 2015 | β |
| Examining the role of common genetic variants on alcohol, tobacco, cannabis and illicit drug dependence: genetics of vulnerability to drug dependence. | Palmer RH et al. | β | 2015 | β |
| Female adolescents with severe substance and conduct problems have substantially less brain gray matter volume. | Dalwani MS et al. | β | 2015 | β |
| Gender differences in the structure of risk for alcohol use disorder in adolescence and young adulthood. | Foster KT et al. | β | 2015 | β |
| Genetic relationship between the addiction diagnosis in adults and their childhood measure of addiction liability. | Vanyukov M et al. | β | 2015 | β |
| Genome-wide association studies of substance use: considerations regarding populations and phenotypes. | Gizer IR et al. | β | 2015 | β |
| Heritability of the neural response to emotional pictures: evidence from ERPs in an adult twin sample. | Weinberg A et al. | β | 2015 | β |
| Impaired Recognition and Regulation of Disgust Is Associated with Distinct but Partially Overlapping Patterns of Decreased Gray Matter Volume in the Ventroanterior Insula. | Woolley JD et al. | β | 2015 | β |
| Increased Pre- and Early-Adolescent Stress in Youth with a Family History of Substance Use Disorder and Early Substance Use Initiation. | Charles NE et al. | β | 2015 | β |
| Internalizing and externalizing psychopathology as predictors of cannabis use disorder onset during adolescence and early adulthood. | Farmer RF et al. | β | 2015 | β |
| Introduction to the special issue: Substance use and the adolescent brain: Developmental impacts, interventions, and longitudinal outcomes. | Luciana M et al. | β | 2015 | β |
| Longitudinal stability and predictive utility of the visual P3 response in adults with externalizing psychopathology. | Yoon HH et al. | β | 2015 | β |
| Neural activation during risky decision-making in youth at high risk for substance use disorders. | Hulvershorn LA et al. | β | 2015 | β |
| Novelty Seeking as a Phenotypic Marker of Adolescent Substance Use. | Bidwell LC et al. | β | 2015 | β |
| Personality psychopathology, drug use and psychological symptoms in adolescents with substance use disorders and community controls. | MagallΓ³n-Neri E et al. | β | 2015 | β |
| Psilocybin, psychological distress, and suicidality. | Hendricks PS et al. | β | 2015 | β |
| Relations Among Internalizing and Externalizing Symptoms and Drinking Frequency During Adolescence. | Jun HJ et al. | β | 2015 | β |
| Reward processing deficits and impulsivity in high-risk offspring of alcoholics: A study of event-related potentials during a monetary gambling task. | Kamarajan C et al. | β | 2015 | β |
| Striatal activity and reduced white matter increase frontal activity in youths with family histories of alcohol and other substance-use disorders performing a go/no-go task. | Acheson A et al. | β | 2015 | β |
| The Power of Theory, Research Design, and Transdisciplinary Integration in Moving Psychopathology Forward. | Vaidyanathan U et al. | β | 2015 | β |
| The role of decision-making in cannabis-related problems among young adults. | Gonzalez R et al. | β | 2015 | β |
| What is the Association of Cannabis Consumption and Cardiovascular Complications? | Panayiotides IM | β | 2015 | β |
| Adolescent alcohol use: risks and consequences. | Marshall EJ | β | 2014 | β |
| Alcohol use disorder in women: Risks and consequences of an adolescent onset and persistent course. | Foster KT et al. | β | 2014 | β |
| A new approach to researching the etiology of cannabis use disorder: integrating transmissible and nontransmissible risk within a developmental framework. | Tarter R et al. | β | 2014 | β |
| An information processing/associative learning account of behavioral disinhibition in externalizing psychopathology. | Endres MJ et al. | β | 2014 | β |
| Anxiety disorders and risk for alcohol use disorders: the moderating effect of parental support. | Gorka SM et al. | β | 2014 | β |
| Assessment of whole brain white matter integrity in youths and young adults with a family history of substance-use disorders. | Acheson A et al. | β | 2014 | β |
| Attention-deficit/hyperactivity disorder and risk of substance use disorder: developmental considerations, potential pathways, and opportunities for research. | Molina BS et al. | β | 2014 | β |
| Attention-deficit/hyperactivity disorder subtypes and substance use and use disorders in NESARC. | De Alwis D et al. | β | 2014 | β |
| Combining diffusion tensor imaging and magnetic resonance spectroscopy to study reduced frontal white matter integrity in youths with family histories of substance use disorders. | Acheson A et al. | β | 2014 | β |
| Delay discounting differentiates pre-adolescents at high and low risk for substance use disorders based on family history. | Dougherty DM et al. | β | 2014 | β |
| Delineating selection and mediation effects among childhood personality and environmental risk factors in the development of adolescent substance abuse. | Hicks BM et al. | β | 2014 | β |
| Early adolescent patterns of alcohol, cigarettes, and marijuana polysubstance use and young adult substance use outcomes in a nationally representative sample. | Moss HB et al. | β | 2014 | β |
| Event-related potentials in substance use disorders: a narrative review based on articles from 1984 to 2012. | Campanella S et al. | β | 2014 | β |
| Examining the efficacy of a personalized normative feedback intervention to reduce college student gambling. | Celio MA et al. | β | 2014 | β |
| Functional magnetic resonance imaging (fMRI) response to alcohol pictures predicts subsequent transition to heavy drinking in college students. | Dager AD et al. | β | 2014 | β |
| Genetic psychophysiology: advances, problems, and future directions. | Anokhin AP | β | 2014 | β |
| Genetic, psychosocial, and demographic factors associated with social disinhibition in Mexican-origin youth. | Archer NP et al. | β | 2014 | β |
| Identifying childhood characteristics that underlie premorbid risk for substance use disorders: socialization and boldness. | Hicks BM et al. | β | 2014 | β |
| Identifying the facets of impulsivity that explain the relation between ADHD symptoms and substance use in a nonclinical sample. | Roberts W et al. | β | 2014 | β |
| Increased forebrain activations in youths with family histories of alcohol and other substance use disorders performing a Go/NoGo task. | Acheson A et al. | β | 2014 | β |
| Longitudinal trajectories of sensation seeking, risk taking propensity, and impulsivity across early to middle adolescence. | Collado A et al. | β | 2014 | β |
| Neural and cognitive correlates of the common and specific variance across externalizing problems in young adolescence. | Castellanos-Ryan N et al. | β | 2014 | β |
| Neurobehavioral aspects of multidimensional psychopathology. | Iacono WG | β | 2014 | β |
| New perspectives on using brain imaging to study CNS stimulants. | Lukas SE | β | 2014 | β |
| Psychological dysregulation during adolescence mediates the association of parent-child attachment in childhood and substance use disorder in adulthood. | Zhai ZW et al. | β | 2014 | β |
| Rare nonsynonymous exonic variants in addiction and behavioral disinhibition. | Vrieze SI et al. | β | 2014 | β |
| Risk-taking and pathological gambling behavior in Huntington's disease. | Kalkhoven C et al. | β | 2014 | β |
| Sexual risk behavior in young adulthood: broadening the scope beyond early sexual initiation. | Epstein M et al. | β | 2014 | β |
| The adolescent origins of substance use disorders: a behavioral genetic perspective. | McGue M et al. | β | 2014 | β |
| The contributions of early adverse experiences and trajectories of respiratory sinus arrhythmia on the development of neurobehavioral disinhibition among children with prenatal substance exposure. | Conradt E et al. | β | 2014 | β |
| The developmental progression of age 14 behavioral disinhibition, early age of sexual initiation, and subsequent sexual risk-taking behavior. | Samek DR et al. | β | 2014 | β |
| The impact of cognitive control, incentives, and working memory load on the P3 responses of externalizing prisoners. | Baskin-Sommers AR et al. | β | 2014 | β |
| The role of constraint in the development of nicotine, marijuana, and alcohol dependence in young adulthood. | Vrieze SI et al. | β | 2014 | β |
| The role of early childhood ADHD and subsequent CD in the initiation and escalation of adolescent cigarette, alcohol, and marijuana use. | Sibley MH et al. | β | 2014 | β |
| Understanding the link between early sexual initiation and later sexually transmitted infection: test and replication in two longitudinal studies. | Epstein M et al. | β | 2014 | β |
| Ventral striatal dopamine synthesis capacity is associated with individual differences in behavioral disinhibition. | Lawrence AD et al. | β | 2014 | β |
| Adolescent substance use in the multimodal treatment study of attention-deficit/hyperactivity disorder (ADHD) (MTA) as a function of childhood ADHD, random assignment to childhood treatments, and subsequent medication. | Molina BS et al. | β | 2013 | β |
| A genome-wide association study of behavioral disinhibition. | McGue M et al. | β | 2013 | β |
| Alcohol and tobacco use disorder comorbidity in young adults and the influence of romantic partner environments. | Meacham MC et al. | β | 2013 | β |
| Alcohol-specific parenting as a mechanism of parental drinking and alcohol use disorder risk on adolescent alcohol use onset. | Handley ED et al. | β | 2013 | β |
| A rapid gene-based genome-wide association test with multivariate traits. | Basu S et al. | β | 2013 | β |
| Association between P3 event-related potential amplitude and externalizing disorders: a time-domain and time-frequency investigation of 29-year-old adults. | Yoon HH et al. | β | 2013 | β |
| Atypical neural activity during inhibitory processing in substance-naΓ―ve youth who later experience alcohol-induced blackouts. | Wetherill RR et al. | β | 2013 | β |
| Behavioral disinhibition and sexual risk behavior among adolescents and young adults in Malawi. | Muchimba M et al. | β | 2013 | β |
| Blunted feedback processing during risky decision making in adolescents with a parental history of substance use disorders. | Euser AS et al. | β | 2013 | β |
| Changes in genetic and environmental influences on trait anxiety Δfrom middle adolescence to early adulthood. | Garcia SE et al. | β | 2013 | β |
| Common genetic and nonshared environmental factors contribute to the association between socioemotional dispositions and the externalizing factor in children. | Taylor J et al. | β | 2013 | β |
| Craving to quit: psychological models and neurobiological mechanisms of mindfulness training as treatment for addictions. | Brewer JA et al. | β | 2013 | β |
| Differential changes in impulsivity and sensation seeking and the escalation of substance use from adolescence to early adulthood. | Quinn PD et al. | β | 2013 | β |
| Do young adults interpret the DSM diagnostic criteria for alcohol use disorders as intended? a cognitive interviewing study. | Slade T et al. | β | 2013 | β |
| Future directions in the developmental science of addictions. | Hussong AM et al. | β | 2013 | β |
| Gene-environment correlation in the development of adolescent substance abuse: selection effects of child personality and mediation via contextual risk factors. | Hicks BM et al. | β | 2013 | β |
| Illegal drugs and delinquency. | Kirschbaum KM et al. | β | 2013 | β |
| Longitudinal twin study of borderline personality disorder traits and substance use in adolescence: developmental change, reciprocal effects, and genetic and environmental influences. | Bornovalova MA et al. | β | 2013 | β |
| P300 amplitude reduction is associated with early-onset and late-onset pathological substance use in a prospectively studied cohort of 14-year-old adolescents. | Perlman G et al. | β | 2013 | β |
| Prospective associations of internalizing and externalizing problems and their co-occurrence with early adolescent substance use. | Colder CR et al. | β | 2013 | β |
| Prospective effects of adolescent indicators of behavioral disinhibition on DSM-IV alcohol, tobacco, and illicit drug dependence in young adulthood. | Palmer RH et al. | β | 2013 | β |
| Relation among HPA and HPG neuroendocrine systems, transmissible risk and neighborhood quality on development of substance use disorder: results of a 10-year prospective study. | Tarter RE et al. | β | 2013 | β |
| Substance-use in Childhood and Adolescence: A Brief Overview of Developmental Processes and their Clinical Implications. | Castellanos-Ryan N et al. | β | 2013 | β |
| Tests of a direct effect of childhood abuse on adult borderline personality disorder traits: a longitudinal discordant twin design. | Bornovalova MA et al. | β | 2013 | β |
| The amphetamine response moderates the relationship between negative emotionality and alcohol use. | Allen KJ et al. | β | 2013 | β |
| The developmental psychopathology of alcohol use and alcohol disorders: research achievements and future directions. | Chassin L et al. | β | 2013 | β |
| The effect of general and drug-specific family environments on comorbid and drug-specific problem behavior: a longitudinal examination. | Epstein M et al. | β | 2013 | β |
| Three mutually informative ways to understand the genetic relationships among behavioral disinhibition, alcohol use, drug use, nicotine use/dependence, and their co-occurrence: twin biometry, GCTA, and genome-wide scoring. | Vrieze SI et al. | β | 2013 | β |
| Time doesn't change everything: the longitudinal course of distress tolerance and its relationship with externalizing and internalizing symptoms during early adolescence. | Cummings JR et al. | β | 2013 | β |
| Translational neuroscience and potential contributions of functional magnetic resonance imaging (FMRI) to the prevention of substance misuse and antisocial behavior. | Whitten LA | β | 2013 | β |
| Adolescent substance use groups: antecedent and concurrent personality differences in a longitudinal study. | Oliva EM et al. | β | 2012 | β |
| A latent class analysis of DSM-IV alcohol use disorder criteria and binge drinking in undergraduates. | Beseler CL et al. | β | 2012 | β |
| Application of person-centered medicine in addiction. | Tarter RE et al. | β | 2012 | β |
| Characterizing the anomalous cognition-emotion interactions in externalizing. | Baskin-Sommers AR et al. | β | 2012 | β |
| Childhood attention-deficit/hyperactivity disorder (ADHD) and growth in adolescent alcohol use: the roles of functional impairments, ADHD symptom persistence, and parental knowledge. | Molina BSG et al. | β | 2012 | β |
| Cognitive control links alcohol use, trait disinhibition, and reduced cognitive capacity: Evidence for medial prefrontal cortex dysregulation during reward-seeking behavior. | Bogg T et al. | β | 2012 | β |
| Common liability to addiction and "gateway hypothesis": theoretical, empirical and evolutionary perspective. | Vanyukov MM et al. | β | 2012 | β |
| Confluence of genes, environment, development, and behavior in a post Genome-Wide Association Study world. | Vrieze SI et al. | β | 2012 | β |
| Decline in genetic influence on the co-occurrence of alcohol, marijuana, and nicotine dependence symptoms from age 14 to 29. | Vrieze SI et al. | β | 2012 | β |
| Differential relationships between sub-traits of BIS-11 impulsivity and executive processes: an ERP study. | Kam JW et al. | β | 2012 | β |
| Disordered gambling among higher-frequency gamblers: who is at risk? | Hodgins DC et al. | β | 2012 | β |
| Examination of the structure of psychopathology using latent class analysis. | Olino TM et al. | β | 2012 | β |
| Examining electrodermal hyporeactivity as a marker of externalizing psychopathology: a twin study. | Isen JD et al. | β | 2012 | β |
| Externalizing behaviors are associated with SNPs in the CHRNA5/CHRNA3/CHRNB4 gene cluster. | Stephens SH et al. | β | 2012 | β |
| Genetic depletion of brain 5HT reveals a common molecular pathway mediating compulsivity and impulsivity. | Angoa-PΓ©rez M et al. | β | 2012 | β |
| Genetic etiology of the common liability to drug dependence: evidence of common and specific mechanisms for DSM-IV dependence symptoms. | Palmer RH et al. | β | 2012 | β |
| Index of the transmissible common liability to addiction: heritability and prospective associations with substance abuse and related outcomes. | Hicks BM et al. | β | 2012 | β |
| Marijuana exposure opportunity and initiation during college: parent and peer influences. | Pinchevsky GM et al. | β | 2012 | β |
| Neurobehavioral disinhibition predicts initiation of substance use in children with prenatal cocaine exposure. | Lester BM et al. | β | 2012 | β |
| Nonmedical use of prescription opioids among adolescents: subtypes based on motivation for use. | Young A et al. | β | 2012 | β |
| Reconceptualizing antisocial deviance in neurobehavioral terms. | Patrick CJ et al. | β | 2012 | β |
| Testing multiple levels of influence in the intergenerational transmission of alcohol disorders from a developmental perspective: the example of alcohol use promoting peers and ΞΌ-opioid receptor M1 variation. | Chassin L et al. | β | 2012 | β |
| The effects of childhood ADHD symptoms on early-onset substance use: a Swedish twin study. | Chang Z et al. | β | 2012 | β |
| The genetics of alcohol dependence: advancing towards systems-based approaches. | Palmer RH et al. | β | 2012 | β |
| The interplay of genes and adolescent development in substance use disorders: leveraging findings from GWAS meta-analyses to test developmental hypotheses about nicotine consumption. | Vrieze SI et al. | β | 2012 | β |
| Topography, power, and current source density of ΞΈ oscillations during reward processing as markers for alcohol dependence. | Kamarajan C et al. | β | 2012 | β |
| Training Self-Control: A Domain-General Translational Neuroscience Approach. | Berkman ET et al. | β | 2012 | β |
| Adolescent Brain Development and Drugs. | Winters KC et al. | β | 2011 | β |
| A framework for the specificity of addictions. | Sussman S et al. | β | 2011 | β |
| An internalizing pathway to alcohol use and disorder. | Hussong AM et al. | β | 2011 | β |
| A unified framework for inhibitory control. | Munakata Y et al. | β | 2011 | β |
| Comorbid psychiatric disorders and nicotine dependence in adolescence. | Griesler PC et al. | β | 2011 | β |
| Developmental Endophenotypes: Indexing Genetic Risk for Substance Abuse with the P300 Brain Event-Related Potential. | Iacono WG et al. | β | 2011 | β |
| Do executive and reactive disinhibition mediate the effects of familial substance use disorders on adolescent externalizing outcomes? | Handley ED et al. | β | 2011 | β |
| Failure to sustain prepulse inhibition in adolescent marijuana users. | Mathias CW et al. | β | 2011 | β |
| Levels of risk: maternal-, middle childhood-, and neighborhood-level predictors of adolescent disinhibitory behaviors from a longitudinal birth cohort in the United States. | Keyes KM et al. | β | 2011 | β |
| Neural activation during inhibition predicts initiation of substance use in adolescence. | Norman AL et al. | β | 2011 | β |
| Parsing the Undercontrol/Disinhibition Pathway to Substance Use Disorders: A Multilevel Developmental Problem. | Zucker RA et al. | β | 2011 | β |
| Personality Measurement and Assessment in Large Panel Surveys* | Roberts B et al. | β | 2011 | β |
| Preliminary evidence for associations of CHRM2 with substance use and disinhibition in adolescence. | Hendershot CS et al. | β | 2011 | β |
| Prospective association of childhood attention-deficit/hyperactivity disorder (ADHD) and substance use and abuse/dependence: a meta-analytic review. | Lee SS et al. | β | 2011 | β |
| Psychometric and genetic architecture of substance use disorder and behavioral disinhibition measures for gene association studies. | Hicks BM et al. | β | 2011 | β |
| Reduced cortical gray matter volume in male adolescents with substance and conduct problems. | Dalwani M et al. | β | 2011 | β |
| The combined effects of prenatal drug exposure and early adversity on neurobehavioral disinhibition in childhood and adolescence. | Fisher PA et al. | β | 2011 | β |
| The effects of psychiatric distress, inhibition, and impulsivity on decision making in patients with substance use disorders: A matched control study. | van Toor D et al. | β | 2011 | β |
| The social norms of birth cohorts and adolescent marijuana use in the United States, 1976-2007. | Keyes KM et al. | β | 2011 | β |
| A parallel process growth mixture model of conduct problems and substance use with risky sexual behavior. | Wu J et al. | β | 2010 | β |
| Are attention lapses related to d-amphetamine liking? | McCloskey M et al. | β | 2010 | β |
| Changes in sensation seeking and risk-taking propensity predict increases in alcohol use among early adolescents. | MacPherson L et al. | β | 2010 | β |
| Consequences of an adolescent onset and persistent course of alcohol dependence in men: adolescent risk factors and adult outcomes. | Hicks BM et al. | β | 2010 | β |
| Disinhibited characteristics and binge drinking among university student drinkers. | Carlson SR et al. | β | 2010 | β |
| Disruptive symptoms in childhood and adolescence and early initiation of tobacco and cannabis use: the Gazel Youth study. | GalΓ©ra C et al. | β | 2010 | β |
| Dysfunctional reward processing in male alcoholics: an ERP study during a gambling task. | Kamarajan C et al. | β | 2010 | β |
| Evaluating the drug use "gateway" theory using cross-national data: consistency and associations of the order of initiation of drug use among participants in the WHO World Mental Health Surveys. | Degenhardt L et al. | β | 2010 | β |
| For distinguished contributions to psychophysiology: William G. Iacono. | Miller GA | β | 2010 | β |
| Individual differences as predictors of illicit drug use among Turkish college students. | Ayvasik HB et al. | β | 2010 | β |
| Measuring addiction propensity and severity: the need for a new instrument. | Conway KP et al. | β | 2010 | β |
| Neural circuitry associated with risk for alcohol use disorders. | Tessner KD et al. | β | 2010 | β |
| Nicotine dependence and problem behaviors among urban South African adolescents. | Pahl K et al. | β | 2010 | β |
| Person-environment interaction in the prediction of alcohol abuse and alcohol dependence in adulthood. | Hill KG et al. | β | 2010 | β |
| Quantifying over-activity in bipolar and schizophrenia patients in a human open field paradigm. | Perry W et al. | β | 2010 | β |
| "Youthful epidemic" or diagnostic bias? Differential item functioning of DSM-IV cannabis use criteria in an Australian general population survey. | Mewton L et al. | β | 2010 | β |
| Alcohol and illicit drug dependence among parents: associations with offspring externalizing disorders. | Marmorstein NR et al. | β | 2009 | β |
| Behavioral disinhibition: liability for externalizing spectrum disorders and its genetic and environmental relation to response inhibition across adolescence. | Young SE et al. | β | 2009 | β |
| Environmental adversity and increasing genetic risk for externalizing disorders. | Hicks BM et al. | β | 2009 | β |
| Externalizing disorders: cluster 5 of the proposed meta-structure for DSM-V and ICD-11. | Krueger RF et al. | β | 2009 | β |
| Intergenerational transmission of alcohol expectancies in a high-risk sample. | Handley ED et al. | β | 2009 | β |
| Introduction and rationale for individualized substance abuse prevention from an ontogenetic perspective. | Ridenour TA et al. | β | 2009 | β |
| Parental alcohol dependence and the transmission of adolescent behavioral disinhibition: a study of adoptive and non-adoptive families. | King SM et al. | β | 2009 | β |
| Refinements in the hierarchical structure of externalizing psychiatric disorders: Patterns of lifetime liability from mid-adolescence through early adulthood. | Farmer RF et al. | β | 2009 | β |
| The enrichment study of the Minnesota twin family study: increasing the yield of twin families at high risk for externalizing psychopathology. | Keyes MA et al. | β | 2009 | β |