Effectiveness of specific RNA-mediated interference through ingested double-stranded RNA in Caenorhabditis elegans.
paper
Cited
Public
- Authors
- Kamath, R S; Martinez-Campos, M; Zipperlen, P; Fraser, A G; Ahringer, J
- Year
- 2001
- Journal
- Genome biology
- PMID
- 11178279
- DOI
- 10.1186/gb-2000-2-1-research0002
- PMCID
- PMC17598
BACKGROUND: In Caenorhabditis elegans, injection of double-stranded RNA (dsRNA) results in the specific inactivation of genes containing homologous sequences, a technique termed RNA-mediated interference (RNAi). It has previously been shown that RNAi can also be achieved by feeding worms Escherichia coli expressing dsRNA corresponding to a specific gene; this mode of dsRNA introduction is conventionally considered to be less efficient than direct injection, however, and has therefore seen limited use, even though it is considerably less labor-intensive. RESULTS: Here we present an optimized feeding method that results in phenotypes at least as strong as those produced by direct injection of dsRNA for embryonic lethal genes, and stronger for genes with post-embryonic phenotypes. In addition, the interference effect generated by feeding can be titrated to uncover a series of hypomorphic phenotypes informative about the functions of a given gene. Using this method, we screened 86 random genes on consecutive cosmids and identified functions for 13 new genes. These included two genes producing an uncoordinated phenotype (a previously uncharacterized POU homeodomain gene, ceh-6, and a gene encoding a MADS-box protein) and one gene encoding a novel protein that results in a high-incidence-of-males phenotype. CONCLUSIONS: RNAi by feeding can provide significant information about the functions of an individual gene beyond that provided by injection. Moreover, it can be used for special applications for which injection or the use of mutants is sometimes impracticable (for example, titration, biochemistry and large-scale screening). Thus, RNAi by feeding should make possible new experimental approaches for the use of genomic sequence information.
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| Sulforaphane Targets TRA-1/GLI Upstream of DAF-16/FOXO to Promote <i>C. elegans</i> Longevity and Healthspan. | Ji H et al. | β | 2021 | β |
| The Argonaute Proteins ALG-1 and ALG-2 Are Linked to Stress Resistance and Proteostasis. | Finger F et al. | β | 2021 | β |
| The CONJUDOR pipeline for multiplexed knockdown of gene pairs identifies RBBP-5 as a germ cell reprogramming barrier in C. elegans. | Kazmierczak M et al. | β | 2021 | β |
| The decrease of intraflagellar transport impairs sensory perception and metabolism in ageing. | Zhang Y et al. | β | 2021 | β |
| The transcription factor LAG-1/CSL plays a Notch-independent role in controlling terminal differentiation, fate maintenance, and plasticity of serotonergic chemosensory neurons. | Maicas M et al. | β | 2021 | β |
| Two human metabolites rescue a C. elegans model of Alzheimer's disease via a cytosolic unfolded protein response. | Joshi P et al. | β | 2021 | β |
| USP7 and VCP<sup>FAF1</sup> define the SUMO/Ubiquitin landscape at the DNA replication fork. | Franz A et al. | β | 2021 | β |
| VHL suppresses RAPTOR and inhibits mTORC1 signaling in clear cell renal cell carcinoma. | Ganner A et al. | β | 2021 | β |
| Wnt signaling establishes the microtubule polarity in neurons through regulation of Kinesin-13. | Puri D et al. | β | 2021 | β |
| Wnt Signaling Induces Asymmetric Dynamics in the Actomyosin Cortex of the <i>C. elegans</i> Endomesodermal Precursor Cell. | Caroti F et al. | β | 2021 | β |
| A cellular surveillance and defense system that delays aging phenotypes in <i>C. elegans</i>. | Hahm JH et al. | β | 2020 | β |
| An ABCG Transporter Functions in Rab Localization and Lysosome-Related Organelle Biogenesis in <i>Caenorhabditis elegans</i>. | Voss L et al. | β | 2020 | β |
| Analysis of Lifespan in C. elegans: Low- and High-Throughput Approaches. | Cornwell AB et al. | β | 2020 | β |
| BTBD9 and dopaminergic dysfunction in the pathogenesis of restless legs syndrome. | Lyu S et al. | β | 2020 | β |
| C. elegans CLASP/CLS-2 negatively regulates membrane ingression throughout the oocyte cortex and is required for polar body extrusion. | Schlientz AJ et al. | β | 2020 | β |
| Characterization of Amyloid Structures in Aging C. Elegans Using Fluorescence Lifetime Imaging. | Pigazzini ML et al. | β | 2020 | β |
| Deficiency of Meis1, a transcriptional regulator, in mice and worms: Neurochemical and behavioral characterizations with implications in the restless legs syndrome. | Lyu S et al. | β | 2020 | β |
| Direct glia-to-neuron transdifferentiation gives rise to a pair of male-specific neurons that ensure nimble male mating. | Molina-GarcΓa L et al. | β | 2020 | β |
| Dose-dependent action of the RNA binding protein FOX-1 to relay X-chromosome number and determine <i>C. elegans</i> sex. | Farboud B et al. | β | 2020 | β |
| Dose-Dependent Effects of GLD-2 and GLD-1 on Germline Differentiation and Dedifferentiation in the Absence of PUF-8. | Park Y et al. | β | 2020 | β |
| FSHR-1/GPCR Regulates the Mitochondrial Unfolded Protein Response in <i>Caenorhabditis elegans</i>. | Kim S et al. | β | 2020 | β |
| Functional diversification of Paramecium Ku80 paralogs safeguards genome integrity during precise programmed DNA elimination. | Abello A et al. | β | 2020 | β |
| HIF-1 Has a Central Role in <i>Caenorhabditis elegans</i> Organismal Response to Selenium. | Romanelli-Credrez L et al. | β | 2020 | β |
| High neural activity accelerates the decline of cognitive plasticity with age in <i>Caenorhabditis elegans</i>. | Li Q et al. | β | 2020 | β |
| <i>Caenorhabditis elegans</i> processes sensory information to choose between freeloading and self-defense strategies. | Schiffer JA et al. | β | 2020 | β |
| <i>Escherichia coli</i> Metabolite Profiling Leads to the Development of an RNA Interference Strain for <i>Caenorhabditis elegans</i>. | Neve IAA et al. | β | 2020 | β |
| <i>Mutator</i> Foci Are Regulated by Developmental Stage, RNA, and the Germline Cell Cycle in <i>Caenorhabditis elegans</i>. | Uebel CJ et al. | β | 2020 | β |
| In vivo CRISPR screening for phenotypic targets of the <i>mir-35-42</i> family in <i>C. elegans</i>. | Yang B et al. | β | 2020 | β |
| LDB1 and the SWI/SNF complex participate in both transcriptional activation and repression by Caenorhabditis elegans BLIMP1/PRDM1. | Fong HT et al. | β | 2020 | β |
| Microtubule assembly and pole coalescence: early steps in <i>C</i><i>aenorhabditis</i><i>elegans</i> oocyte meiosis I spindle assembly. | Chuang CH et al. | β | 2020 | β |
| Mitochondrial dysfunction induces RNA interference in C. elegans through a pathway homologous to the mammalian RIG-I antiviral response. | Mao K et al. | β | 2020 | β |
| Mitochondrial translation and dynamics synergistically extend lifespan in C. elegans through HLH-30. | Liu YJ et al. | β | 2020 | β |
| Modeling neurodegeneration in <i>Caenorhabditis</i><i>elegans</i>. | Caldwell KA et al. | β | 2020 | β |
| Molecular characterization of RNase III protein of Asaia sp. for developing a robust RNAi-based paratransgensis tool to affect the sexual life-cycle of Plasmodium or Anopheles fitness. | Asgari M et al. | β | 2020 | β |
| NemaLife chip: a micropillar-based microfluidic culture device optimized for aging studies in crawling C. elegans. | Rahman M et al. | β | 2020 | β |
| New Roles for the Heterochronic Transcription Factor LIN-29 in Cuticle Maintenance and Lipid Metabolism at the Larval-to-Adult Transition in <i>Caenorhabditis elegans</i>. | Abete-Luzi P et al. | β | 2020 | β |
| NLR-1/CASPR Anchors F-Actin to Promote Gap Junction Formation. | Meng L et al. | β | 2020 | β |
| PLK-1 promotes the merger of the parental genome into a single nucleus by triggering lamina disassembly. | Velez-Aguilera G et al. | β | 2020 | β |
| PTP-3 phosphatase promotes intramolecular folding of SYD-2 to inactivate kinesin-3 UNC-104 in neurons. | Muniesh MS et al. | β | 2020 | β |
| Roles for the RNA polymerase III regulator MAFR-1 in regulating sperm quality in Caenorhabditis elegans. | Hammerquist AM et al. | β | 2020 | β |
| Stoichiometric interactions explain spindle dynamics and scaling across 100 million years of nematode evolution. | Farhadifar R et al. | β | 2020 | β |
| The C. elegans miR-235 regulates the toxicity of graphene oxide via targeting the nuclear hormone receptor DAF-12 in the intestine. | Guo T et al. | β | 2020 | β |
| The Role of <i>pkc-3</i> and Genetic Suppressors in <i>Caenorhabditis elegans</i> Epithelial Cell Junction Formation. | Montoyo-Rosario JG et al. | β | 2020 | β |
| Three Rules Explain Transgenerational Small RNA Inheritance in C.Β elegans. | Houri-Zeevi L et al. | β | 2020 | β |
| trans-Fatty acids facilitate DNA damage-induced apoptosis through the mitochondrial JNK-Sab-ROS positive feedback loop. | Hirata Y et al. | β | 2020 | β |
| Tyramine Acts Downstream of Neuronal XBP-1s to Coordinate Inter-tissue UPR<sup>ER</sup> Activation and Behavior in C.Β elegans. | Γzbey NP et al. | β | 2020 | β |
| UBC-9 Acts in GABA Neurons to Control Neuromuscular Signaling in <i>C. elegans</i>. | Kreyden VA et al. | β | 2020 | β |
| Verapamil extends lifespan in <i>Caenorhabditis elegans</i> by inhibiting calcineurin activity and promoting autophagy. | Liu W et al. | β | 2020 | β |
| WNT regulates programmed muscle remodeling through PLC-Ξ² and calcineurin in <i>Caenorhabditis elegans</i> males. | LeBoeuf B et al. | β | 2020 | β |
| Ξ±- and Ξ²-Santalols Delay Aging in <i>Caenorhabditis elegans</i> via Preventing Oxidative Stress and Protein Aggregation. | Mohankumar A et al. | β | 2020 | β |
| A microRNA switch controls dietary restriction-induced longevity through Wnt signaling. | Xu Y et al. | β | 2019 | β |
| A Novel Caenorhabditis Elegans Proteinopathy Model Shows Changes in mRNA Translational Frameshifting During Aging. | Adamla F et al. | β | 2019 | β |
| A secreted microRNA disrupts autophagy in distinct tissues of Caenorhabditis elegans upon ageing. | Zhou Y et al. | β | 2019 | β |
| Aurora A depletion reveals centrosome-independent polarization mechanism in <i>Caenorhabditis elegans</i>. | Klinkert K et al. | β | 2019 | β |
| Bacterial diet and weak cadmium stress affect the survivability of <i>Caenorhabditis elegans</i> and its resistance to severe stress. | DΓΆlling R et al. | β | 2019 | β |
| C. elegans protein interaction network analysis probes RNAi validated pro-longevity effect of nhr-6, a human homolog of tumor suppressor Nr4a1. | Akhoon BA et al. | β | 2019 | β |
| Central-spindle microtubules are strongly coupled to chromosomes during both anaphase A and anaphase B. | Yu CH et al. | β | 2019 | β |
| CHP1 Regulates Compartmentalized Glycerolipid Synthesis by Activating GPAT4. | Zhu XG et al. | β | 2019 | β |
| Conserved role for Ataxin-2 in mediating endoplasmic reticulum dynamics. | Del Castillo U et al. | β | 2019 | β |
| Construction of a germline-specific RNAi tool in C. elegans. | Zou L et al. | β | 2019 | β |
| Developmental fidelity is imposed by genetically separable RalGEF activities that mediate opposing signals. | Shin H et al. | β | 2019 | β |
| Dietary restriction induces posttranscriptional regulation of longevity genes. | Rollins JA et al. | β | 2019 | β |
| Disruption in A-to-I Editing Levels Affects C.Β elegans Development More Than a Complete Lack of Editing. | Ganem NS et al. | β | 2019 | β |
| Functional importance of an inverted formin C-terminal tail at morphologically dynamic epithelial junctions. | Hegsted A et al. | β | 2019 | β |
| Gain-of-function mutations in the UNC-2/CaV2Ξ± channel lead to excitation-dominant synaptic transmission in <i>Caenorhabditis elegans</i>. | Huang YC et al. | β | 2019 | β |
| Glycine promotes longevity in Caenorhabditis elegans in a methionine cycle-dependent fashion. | Liu YJ et al. | β | 2019 | β |
| Heterochromatic foci and transcriptional repression by an unstructured MET-2/SETDB1 co-factor LIN-65. | Delaney CE et al. | β | 2019 | β |
| Insights on UNC-104-dynein/dynactin interactions and their implications on axonal transport in Caenorhabditis elegans. | Chen CW et al. | β | 2019 | β |
| <i>PcMuORP1</i>, an Oxathiapiprolin-Resistance Gene, Functions as a Novel Selection Marker for <i>Phytophthora</i> Transformation and CRISPR/Cas9 Mediated Genome Editing. | Wang W et al. | β | 2019 | β |
| Lifespan Extension in C.Β elegans Caused by Bacterial Colonization of the Intestine and Subsequent Activation of an Innate Immune Response. | Kumar S et al. | β | 2019 | β |
| Liposome-based transfection enhances RNAi and CRISPR-mediated mutagenesis in non-model nematode systems. | Adams S et al. | β | 2019 | β |
| Maintenance of cell fates and regulation of the histone variant H3.3 by TLK kinase in <i>Caenorhabditis elegans</i>. | Shibata Y et al. | β | 2019 | β |
| Mitotic Cell Division in <i>Caenorhabditis elegans</i>. | Pintard L et al. | β | 2019 | β |
| MRG-1/MRG15 Is a Barrier for Germ Cell to Neuron Reprogramming in <i>Caenorhabditis elegans</i>. | Hajduskova M et al. | β | 2019 | β |
| Nematicidal actions of the marigold exudate Ξ±-terthienyl: oxidative stress-inducing compound penetrates nematode hypodermis. | Hamaguchi T et al. | β | 2019 | β |
| Neuronal XBP-1 Activates Intestinal Lysosomes to Improve Proteostasis in C.Β elegans. | Imanikia S et al. | β | 2019 | β |
| Olfaction regulates organismal proteostasis and longevity via microRNA-dependent signaling. | Finger F et al. | β | 2019 | β |
| Pathogenetic basis of Takenouchi-Kosaki syndrome: Electron microscopy study using platelets in patients and functional studies in a Caenorhabditis elegans model. | Uehara T et al. | β | 2019 | β |
| Production of YP170 Vitellogenins Promotes Intestinal Senescence in Caenorhabditis elegans. | Sornda T et al. | β | 2019 | β |
| RNAi-Mediated Knockdown of <i>Tssk1</i> and <i>Tektin1</i> Genes Impair Male Fertility in <i>Bactrocera dorsalis</i>. | Sohail S et al. | β | 2019 | β |
| The RNA-Binding Protein PUM2 Impairs Mitochondrial Dynamics and Mitophagy During Aging. | D'Amico D et al. | β | 2019 | β |
| The Role of Tissue Inhibitors of Metalloproteinases in Organ Development and Regulation of ADAMTS Family Metalloproteinases in <i>Caenorhabditis elegans</i>. | Kubota Y et al. | β | 2019 | β |
| The small GTPase ARF-1.2 is a regulator of unicellular tube formation in Caenorhabditis elegans. | Kage-Nakadai E et al. | β | 2019 | β |
| The Transcription Factors TFEB and TFE3 Link the FLCN-AMPK Signaling Axis to Innate Immune Response and Pathogen Resistance. | El-Houjeiri L et al. | β | 2019 | β |
| Tissue- and sex-specific small RNAomes reveal sex differences in response to the environment. | Bezler A et al. | β | 2019 | β |
| Translational Regulation of Non-autonomous Mitochondrial Stress Response Promotes Longevity. | Lan J et al. | β | 2019 | β |
| WormBot, an open-source robotics platform for survival and behavior analysis in C. elegans. | Pitt JN et al. | β | 2019 | β |
| XBP-1 Remodels Lipid Metabolism to Extend Longevity. | Imanikia S et al. | β | 2019 | β |
| A Damage Sensor Associated with the Cuticle Coordinates Three Core Environmental Stress Responses in <i>Caenorhabditis elegans</i>. | Dodd W et al. | β | 2018 | β |
| Application of RNAi and Heat-shock-induced Transcription Factor Expression to Reprogram Germ Cells to Neurons in C. elegans. | Kolundzic E et al. | β | 2018 | β |
| Caenorhabditis elegans BRICHOS Domain-Containing Protein C09F5.1 Maintains Thermotolerance and Decreases Cytotoxicity of AΞ²<sub>42</sub> by Activating the UPR. | Song M et al. | β | 2018 | β |
| CGEF-1 regulates mTORC1 signaling during adult longevity and stress response in <i>C. elegans</i>. | Li Y et al. | β | 2018 | β |
| Cilium Length and Intraflagellar Transport Regulation by Kinases PKG-1 and GCK-2 in Caenorhabditis elegans Sensory Neurons. | Muthaiyan Shanmugam M et al. | β | 2018 | β |
| DAF-21/Hsp90 is required for C. elegans longevity by ensuring DAF-16/FOXO isoform A function. | SomogyvΓ‘ri M et al. | β | 2018 | β |
| De novo NAD<sup>+</sup> synthesis enhances mitochondrial function and improves health. | Katsyuba E et al. | β | 2018 | β |
| Developmental basis for intestinal barrier against the toxicity of graphene oxide. | Ren M et al. | β | 2018 | β |
| Enhanced longevity and metabolism by brown adipose tissue with disruption of the regulator of G protein signaling 14. | Vatner DE et al. | β | 2018 | β |
| FACT complex gene duplicates exhibit redundant and non-redundant functions in C. elegans. | Suggs BZ et al. | β | 2018 | β |
| Function and regulation of the Caenorhabditis elegans Rab32 family member GLO-1 in lysosome-related organelle biogenesis. | Morris C et al. | β | 2018 | β |
| G2019S LRRK2 Increases Stress Susceptibility Through Inhibition of DAF-16 Nuclear Translocation in a 14-3-3 Associated-Manner in <i>Caenorhabditis elegans</i>. | Long S et al. | β | 2018 | β |
| Genomic identification and functional analysis of essential genes in Caenorhabditis elegans. | Yu S et al. | β | 2018 | β |
| Highly efficient RNAi and Cas9-based auto-cloning systems for C. elegans research. | Sturm Γ et al. | β | 2018 | β |
| Hsp90 Stabilizes SIRT1 Orthologs in Mammalian Cells and <i>C. elegans</i>. | Nguyen MT et al. | β | 2018 | β |
| MAPK signaling couples SCF-mediated degradation of translational regulators to oocyte meiotic progression. | Kisielnicka E et al. | β | 2018 | β |
| Microtubule Dynamics Scale with Cell Size to Set Spindle Length and Assembly Timing. | Lacroix B et al. | β | 2018 | β |
| Mitoferrin-1 is Involved in the Progression of Alzheimer's Disease Through Targeting Mitochondrial Iron Metabolism in a Caenorhabditis elegans Model of Alzheimer's Disease. | Huang J et al. | β | 2018 | β |
| Modeling Parkinson's Disease in C. elegans. | Cooper JF et al. | β | 2018 | β |
| Molecular genetic and biochemical characterization of a putative family of zinc metalloproteins in Caenorhabditis elegans. | Chaudhuri P et al. | β | 2018 | β |
| Nicotinamide-N-methyltransferase controls behavior, neurodegeneration and lifespan by regulating neuronal autophagy. | Schmeisser K et al. | β | 2018 | β |
| Novel Bioactive Peptides from <i>Meretrix meretrix</i> Protect <i>Caenorhabditis elegans</i> against Free Radical-Induced Oxidative Stress through the Stress Response Factor DAF-16/FOXO. | Jia W et al. | β | 2018 | β |
| NPR-9 regulates the innate immune response in Caenorhabditis elegans by antagonizing the activity of AIB interneurons. | Yu Y et al. | β | 2018 | β |
| Nuclear Export Inhibition Enhances HLH-30/TFEB Activity, Autophagy, and Lifespan. | Silvestrini MJ et al. | β | 2018 | β |
| Phosphatidylinositol-5-Phosphate 4-Kinases Regulate Cellular Lipid Metabolism By Facilitating Autophagy. | Lundquist MR et al. | β | 2018 | β |
| PI(4,5)P<sub>2</sub> forms dynamic cortical structures and directs actin distribution as well as polarity in <i>Caenorhabditis elegans</i> embryos. | Scholze MJ et al. | β | 2018 | β |
| Plate Design for and Cherry Picking of Bacterial RNAi Clones for Systematic Error Detection in High-Throughput Caenorhabditis elegans RNAi Screens. | Jagadeesan S et al. | β | 2018 | β |
| PRP-19, a conserved pre-mRNA processing factor and E3 ubiquitin ligase, inhibits the nuclear accumulation of GLP-1/Notch intracellular domain. | Gutnik S et al. | β | 2018 | β |
| Regulation of C. elegans L4 cuticle collagen genes by the heterochronic protein LIN-29. | Abete-Luzi P et al. | β | 2018 | β |
| RNAi Screening: Automated High-Throughput Liquid RNAi Screening in Caenorhabditis elegans. | Jagadeesan S et al. | β | 2018 | β |
| Sesamin extends lifespan through pathways related to dietary restriction in Caenorhabditis elegans. | Nakatani Y et al. | β | 2018 | β |
| Six domesticated PiggyBac transposases together carry out programmed DNA elimination in <i>Paramecium</i>. | Bischerour J et al. | β | 2018 | β |
| Spectrin regulates cell contractility through production and maintenance of actin bundles in the Caenorhabditis elegans spermatheca. | Wirshing ACE et al. | β | 2018 | β |
| Sphingomyelin Metabolism Is a Regulator of K-Ras Function. | van der Hoeven D et al. | β | 2018 | β |
| Spindle assembly checkpoint strength is linked to cell fate in the Caenorhabditis elegans embryo. | Gerhold AR et al. | β | 2018 | β |
| Subunits of the DNA polymerase alpha-primase complex promote Notch-mediated proliferation with discrete and shared functions in C. elegans germline. | Yoon DS et al. | β | 2018 | β |
| The polarity protein VANG-1 antagonizes Wnt signaling by facilitating Frizzled endocytosis. | He CW et al. | β | 2018 | β |
| The Replica Set Method: A High-throughput Approach to Quantitatively Measure Caenorhabditis elegans Lifespan. | Cornwell AB et al. | β | 2018 | β |
| The small GTPase RAB-35 defines a third pathway that is required for the recognition and degradation of apoptotic cells. | Haley R et al. | β | 2018 | β |
| The transcription factor SKN-1 and detoxification gene ugt-22 alter albendazole efficacy in Caenorhabditis elegans. | Fontaine P et al. | β | 2018 | β |
| Transgenerational Sterility of Piwi Mutants Represents a Dynamic Form of Adult Reproductive Diapause. | Heestand B et al. | β | 2018 | β |
| Translational Geroscience: From invertebrate models to companion animal and human interventions. | Lee MB et al. | β | 2018 | β |
| A casein kinase 1 prevents expulsion of the oocyte meiotic spindle into a polar body by regulating cortical contractility. | Flynn JR et al. | β | 2017 | β |
| A homozygous missense mutation in ERAL1, encoding a mitochondrial rRNA chaperone, causes Perrault syndrome. | Chatzispyrou IA et al. | β | 2017 | β |
| An asymmetric attraction model for the diversity and robustness of cell arrangement in nematodes. | Yamamoto K et al. | β | 2017 | β |
| An in vivo genetic screen for genes involved in spliced leader trans-splicing indicates a crucial role for continuous de novo spliced leader RNP assembly. | Philippe L et al. | β | 2017 | β |
| Artificial and natural RNA interactions between bacteria and C. elegans. | Braukmann F et al. | β | 2017 | β |
| Axon regeneration in C. elegans: Worming our way to mechanisms of axon regeneration. | Byrne AB et al. | β | 2017 | β |
| Centriolar SAS-7 acts upstream of SPD-2 to regulate centriole assembly and pericentriolar material formation. | Sugioka K et al. | β | 2017 | β |
| Channel Nucleoporins Recruit PLK-1 to Nuclear Pore Complexes to Direct Nuclear Envelope Breakdown in C.Β elegans. | Martino L et al. | β | 2017 | β |
| Cholesterol regulates DAF-16 nuclear localization and fasting-induced longevity in C. elegans. | Ihara A et al. | β | 2017 | β |
| Enhancing mitochondrial proteostasis reduces amyloid-Ξ² proteotoxicity. | Sorrentino V et al. | β | 2017 | β |
| Environmental stresses induce transgenerationally inheritable survival advantages via germline-to-soma communication in Caenorhabditis elegans. | Kishimoto S et al. | β | 2017 | β |
| Genetic Variants of Microtubule Actin Cross-linking Factor 1 (MACF1) Confer Risk for Parkinson's Disease. | Wang X et al. | β | 2017 | β |
| Genomewide Association Study of Alcohol Dependence Identifies Risk Loci Altering Ethanol-Response Behaviors in Model Organisms. | Adkins AE et al. | β | 2017 | β |
| Habituation as an adaptive shift in response strategy mediated by neuropeptides. | Ardiel EL et al. | β | 2017 | β |
| Identification of regulators of germ stem cell enwrapment by its niche in C. elegans. | Linden LM et al. | β | 2017 | β |
| Impaired DNA replication derepresses chromatin and generates a transgenerationally inherited epigenetic memory. | Klosin A et al. | β | 2017 | β |
| Implementing the sterile insect technique with RNA interference - a review. | Darrington M et al. | β | 2017 | β |
| mir-355 Functions as An Important Link between p38 MAPK Signaling and Insulin Signaling in the Regulation of Innate Immunity. | Zhi L et al. | β | 2017 | β |
| Molecular Control of Innate Immune Response to Pseudomonas aeruginosa Infection by Intestinal let-7 in Caenorhabditis elegans. | Zhi L et al. | β | 2017 | β |
| MPK-1/ERK regulatory network controls the number of sperm by regulating timing of sperm-oocyte switch in C.Β elegans germline. | Yoon DS et al. | β | 2017 | β |
| Natural Genetic Variation in the <i>Caenorhabditis elegans</i> Response to <i>Pseudomonas aeruginosa</i>. | Martin N et al. | β | 2017 | β |
| Neuronal function of the mRNA decapping complex determines survival of <i>Caenorhabditis elegans</i> at high temperature through temporal regulation of heterochronic gene expression. | Borbolis F et al. | β | 2017 | β |
| PAR proteins regulate maintenance-phase myosin dynamics during <i>Caenorhabditis elegans</i> zygote polarization. | Small LE et al. | β | 2017 | β |
| PQN-75 is expressed in the pharyngeal gland cells of <i>C</i><i>aenorhabditis</i><i>elegans</i> and is dispensable for germline development. | Rochester JD et al. | β | 2017 | β |
| PRMT-5 converts monomethylarginines into symmetrical dimethylarginines in Caenorhabditis elegans. | Kanou A et al. | β | 2017 | β |
| RNA Interference: A Novel Source of Resistance to Combat Plant Parasitic Nematodes. | Banerjee S et al. | β | 2017 | β |
| RNAi targeting <i>Caenorhabditis elegans</i> Ξ±-arrestins has little effect on lifespan. | Park S et al. | β | 2017 | β |
| Small nucleoli are a cellular hallmark of longevity. | Tiku V et al. | β | 2017 | β |
| Spatial function of the oxidative DNA damage response in radiation induced bystander effects in intra- and inter-system of <i>Caenorhabditis elegans</i>. | Li Q et al. | β | 2017 | β |
| The C. elegans Excretory Canal as a Model for Intracellular Lumen Morphogenesis and In Vivo Polarized Membrane Biogenesis in a Single Cell: labeling by GFP-fusions, RNAi Interaction Screen and Imaging. | Zhang N et al. | β | 2017 | β |
| The C. elegans Intestine As a Model for Intercellular Lumen Morphogenesis and In Vivo Polarized Membrane Biogenesis at the Single-cell Level: Labeling by Antibody Staining, RNAi Loss-of-function Analysis and Imaging. | Zhang N et al. | β | 2017 | β |
| The cell non-autonomous function of ATG-18 is essential for neuroendocrine regulation of Caenorhabditis elegans lifespan. | Minnerly J et al. | β | 2017 | β |
| The microRNA machinery regulates fasting-induced changes in gene expression and longevity in <i>Caenorhabditis elegans</i>. | Kogure A et al. | β | 2017 | β |
| The MYST family histone acetyltransferase complex regulates stress resistance and longevity through transcriptional control of DAF-16/FOXO transcription factors. | Ikeda T et al. | β | 2017 | β |
| The VPS34 PI3K negatively regulates RAB-5 during endosome maturation. | Law F et al. | β | 2017 | β |
| Transgenic Cotton Plants Expressing the HaHR3 Gene Conferred Enhanced Resistance to Helicoverpa armigera and Improved Cotton Yield. | Han Q et al. | β | 2017 | β |
| Trojan Horse Strategy for Non-invasive Interference of Clock Gene in the Oyster Crassostrea gigas. | Payton L et al. | β | 2017 | β |
| Variations on a theme: Imaging cytokinetic and stable rings in situ using Caenorhabditis elegans. | Rehain K et al. | β | 2017 | β |
| WASP-Arp2/3-dependent actin polymerization influences fusogen localization during cell-cell fusion in <i>Caenorhabditis</i><i>elegans</i> embryos. | Zhang Y et al. | β | 2017 | β |
| Ξ²-Integrin de-phosphorylation by the Density-Enhanced Phosphatase DEP-1 attenuates EGFR signaling in C. elegans. | Walser M et al. | β | 2017 | β |
| A Caenorhabditis elegans Homologue of LYST Functions in Endosome and Lysosome-Related Organelle Biogenesis. | Barrett A et al. | β | 2016 | β |
| A MicroRNA-Mediated Insulin Signaling Pathway Regulates the Toxicity of Multi-Walled Carbon Nanotubes in Nematode Caenorhabditis elegans. | Zhao Y et al. | β | 2016 | β |
| A mir-231-Regulated Protection Mechanism against the Toxicity of Graphene Oxide in Nematode Caenorhabditis elegans. | Yang R et al. | β | 2016 | β |
| Angiotensin Converting Enzyme (ACE) Inhibitor Extends Caenorhabditis elegans Life Span. | Kumar S et al. | β | 2016 | β |
| A novel chromosome segregation mechanism during female meiosis. | McNally KP et al. | β | 2016 | β |
| Antagonistic Behaviors of NMY-1 and NMY-2 Maintain Ring Channels in the C.Β elegans Gonad. | Coffman VC et al. | β | 2016 | β |
| A theoretical model of cytokinesis implicates feedback between membrane curvature and cytoskeletal organization in asymmetric cytokinetic furrowing. | Dorn JF et al. | β | 2016 | β |
| A Two-Immunoglobulin-Domain Transmembrane Protein Mediates an Epidermal-Neuronal Interaction to Maintain Synapse Density. | Cherra SJ et al. | β | 2016 | β |
| Automated longitudinal monitoring of in vivo protein aggregation in neurodegenerative disease C. elegans models. | Cornaglia M et al. | β | 2016 | β |
| Caenorhabditis elegans homologue of Prox1/Prospero is expressed in the glia and is required for sensory behavior and cold tolerance. | Kage-Nakadai E et al. | β | 2016 | β |
| CDC-25.2, a C. elegans ortholog of cdc25, is essential for the progression of intestinal divisions. | Lee YU et al. | β | 2016 | β |
| C. elegans miro-1 Mutation Reduces the Amount of Mitochondria and Extends Life Span. | Shen Y et al. | β | 2016 | β |
| Cell cycle controls stress response and longevity in <i>C. elegans</i>. | Dottermusch M et al. | β | 2016 | β |
| Chromatin-associated degradation is defined by UBXN-3/FAF1 to safeguard DNA replication fork progression. | Franz A et al. | β | 2016 | β |
| Chromosome-wide mechanisms to decouple gene expression from gene dose during sex-chromosome evolution. | Wheeler BS et al. | β | 2016 | β |
| Developmentally programmed germ cell remodelling by endodermal cell cannibalism. | Abdu Y et al. | β | 2016 | β |
| Dynein-mediated trafficking negatively regulates LET-23 EGFR signaling. | Skorobogata O et al. | β | 2016 | β |
| Endomembrane-associated RSD-3 is important for RNAi induced by extracellular silencing RNA in both somatic and germ cells of Caenorhabditis elegans. | Imae R et al. | β | 2016 | β |
| Fine-tuning of chromatin composition and Polycomb recruitment by two Mi2 homologues during C. elegans early embryonic development. | KΓ€ser-PΓ©bernard S et al. | β | 2016 | β |
| FLP-4 neuropeptide and its receptor in a neuronal circuit regulate preference choice through functions of ASH-2 trithorax complex in Caenorhabditis elegans. | Yu Y et al. | β | 2016 | β |
| Forward Genetic Screen in <i>Caenorhabditis elegans</i> Suggests F57A10.2 and acp-4 As Suppressors of C9ORF72 Related Phenotypes. | Wang X et al. | β | 2016 | β |
| Function of the C. elegans T-box factor TBX-2 depends on interaction with the UNC-37/Groucho corepressor. | Huber P et al. | β | 2016 | β |
| Identification and functional analysis of secreted effectors from phytoparasitic nematodes. | Rehman S et al. | β | 2016 | β |
| Identification of microtubule growth deceleration and its regulation by conserved and novel proteins. | Lacroix B et al. | β | 2016 | β |
| Identifying Regulators of Morphogenesis Common to Vertebrate Neural Tube Closure and Caenorhabditis elegans Gastrulation. | Sullivan-Brown JL et al. | β | 2016 | β |
| Inhibition of the oxidative stress response by heat stress in Caenorhabditis elegans. | Crombie TA et al. | β | 2016 | β |
| Intestinal Insulin Signaling Encodes Two Different Molecular Mechanisms for the Shortened Longevity Induced by Graphene Oxide in Caenorhabditis elegans. | Zhao Y et al. | β | 2016 | β |
| In Vivo Interaction Proteomics in Caenorhabditis elegans Embryos Provides New Insights into P Granule Dynamics. | Chen JX et al. | β | 2016 | β |
| Kinetics and specificity of paternal mitochondrial elimination in Caenorhabditis elegans. | Wang Y et al. | β | 2016 | β |
| Long-term time-lapse microscopy of C. elegans post-embryonic development. | Gritti N et al. | β | 2016 | β |
| Metallothioneins act downstream of insulin signaling to regulate toxicity of outdoor fine particulate matter (PM<sub>2.5</sub>) during Spring Festival in Beijing in nematode <i>Caenorhabditis elegans</i>. | Yang R et al. | β | 2016 | β |
| Mg2+ Extrusion from Intestinal Epithelia by CNNM Proteins Is Essential for Gonadogenesis via AMPK-TORC1 Signaling in Caenorhabditis elegans. | Ishii T et al. | β | 2016 | β |
| Nuclear Envelope Retention of LINC Complexes Is Promoted by SUN-1 Oligomerization in the Caenorhabditis elegans Germ Line. | Daryabeigi A et al. | β | 2016 | β |
| Nucleotide levels regulate germline proliferation through modulating GLP-1/Notch signaling in C. elegans. | Chi C et al. | β | 2016 | β |
| Olfactory stem cells reveal MOCOS as a new player in autism spectrum disorders. | FΓ©ron F et al. | β | 2016 | β |
| Polo-like kinase phosphorylation determines Caenorhabditis elegans centrosome size and density by biasing SPD-5 toward an assembly-competent conformation. | Wueseke O et al. | β | 2016 | β |
| Reducing translation through eIF4G/IFG-1 improves survival under ER stress that depends on heat shock factor HSF-1 in Caenorhabditis elegans. | Howard AC et al. | β | 2016 | β |
| RNAi-Based Suppressor Screens Reveal Genetic Interactions Between the CRL2LRR-1 E3-Ligase and the DNA Replication Machinery in Caenorhabditis elegans. | Ossareh-Nazari B et al. | β | 2016 | β |
| RNAi-Mediated Inactivation of Autophagy Genes in Caenorhabditis elegans. | Palmisano NJ et al. | β | 2016 | β |
| Run-on of germline apoptosis promotes gonad senescence in C. elegans. | de la Guardia Y et al. | β | 2016 | β |
| The high-throughput production of dsRNA against sacbrood virus for use in the honey bee Apis cerana (Hymenoptera: Apidae). | Zhang J et al. | β | 2016 | β |
| The Movement Tracker: A Flexible System for Automated Movement Analysis in Invertebrate Model Organisms. | Mouchiroud L et al. | β | 2016 | β |
| The Paired-box protein PAX-3 regulates the choice between lateral and ventral epidermal cell fates in C. elegans. | Thompson KW et al. | β | 2016 | β |
| The RNA-binding protein ATX-2 regulates cytokinesis through PAR-5 and ZEN-4. | Gnazzo MM et al. | β | 2016 | β |
| Uncoupling Protein, UCP-4 May Be Involved in Neuronal Defects During Aging and Resistance to Pathogens in Caenorhabditis elegans. | Cho I et al. | β | 2016 | β |
| Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents. | Ryu D et al. | β | 2016 | β |
| AMP-Activated Kinase Regulates Lipid Droplet Localization and Stability of Adipose Triglyceride Lipase in C. elegans Dauer Larvae. | Xie M et al. | β | 2015 | β |
| An instructive role for C. elegans E-cadherin in translating cell contact cues into cortical polarity. | Klompstra D et al. | β | 2015 | β |
| Aquaporins-2 and -4 regulate glycogen metabolism and survival during hyposmotic-anoxic stress in Caenorhabditis elegans. | LaMacchia JC et al. | β | 2015 | β |
| Asymmetric transcript discovery by RNA-seq in C. elegans blastomeres identifies neg-1, a gene important for anterior morphogenesis. | Osborne Nishimura E et al. | β | 2015 | β |
| A Transparent Window into Biology: A Primer on Caenorhabditis elegans. | Corsi AK et al. | β | 2015 | β |
| Autonomous and nonautonomous regulation of Wnt-mediated neuronal polarity by the C. elegans Ror kinase CAM-1. | Chien SC et al. | β | 2015 | β |
| Cdk1 phosphorylates SPAT-1/Bora to trigger PLK-1 activation and drive mitotic entry in C. elegans embryos. | Tavernier N et al. | β | 2015 | β |
| Cell nonautonomous activation of flavin-containing monooxygenase promotes longevity and health span. | Leiser SF et al. | β | 2015 | β |
| Cellular hallmarks reveal restricted aerobic metabolism at thermal limits. | Neves A et al. | β | 2015 | β |
| Centrosomes. Regulated assembly of a supramolecular centrosome scaffold in vitro. | Woodruff JB et al. | β | 2015 | β |
| Chromoanasynthetic Genomic Rearrangement Identified in a N-Ethyl-N-Nitrosourea (ENU) Mutagenesis Screen in Caenorhabditis elegans. | Itani OA et al. | β | 2015 | β |
| Control of stem cell self-renewal and differentiation by the heterochronic genes and the cellular asymmetry machinery in Caenorhabditis elegans. | Harandi OF et al. | β | 2015 | β |
| Dauer-independent insulin/IGF-1-signalling implicates collagen remodelling in longevity. | Ewald CY et al. | β | 2015 | β |
| Disruption of the C. elegans Intestinal Brush Border by the Fungal Lectin CCL2 Phenocopies Dietary Lectin Toxicity in Mammals. | Stutz K et al. | β | 2015 | β |
| Distinct roles of the RasGAP family proteins in C. elegans associative learning and memory. | GyurkΓ³ MD et al. | β | 2015 | β |
| Dynactin-dependent cortical dynein and spherical spindle shape correlate temporally with meiotic spindle rotation in Caenorhabditis elegans. | Crowder ME et al. | β | 2015 | β |
| Epoxides Derived from Dietary Dihomo-Gamma-Linolenic Acid Induce Germ Cell Death in C. elegans. | Deline M et al. | β | 2015 | β |
| FLCN and AMPK Confer Resistance to Hyperosmotic Stress via Remodeling of Glycogen Stores. | Possik E et al. | β | 2015 | β |
| FOXA1 modulates EAF2 regulation of AR transcriptional activity, cell proliferation, and migration in prostate cancer cells. | Guo W et al. | β | 2015 | β |
| Genome-wide RNAi screen for synthetic lethal interactions with the C. elegans kinesin-5 homolog BMK-1. | Maia AF et al. | β | 2015 | β |
| Glycosyl phosphatidylinositol anchor biosynthesis is essential for maintaining epithelial integrity during Caenorhabditis elegans embryogenesis. | Budirahardja Y et al. | β | 2015 | β |
| Guanine nucleotide exchange factor OSG-1 confers functional aging via dysregulated Rho signaling in Caenorhabditis elegans neurons. | Duan Z et al. | β | 2015 | β |
| Identification of nonviable genes affecting touch sensitivity in Caenorhabditis elegans using neuronally enhanced feeding RNA interference. | Chen X et al. | β | 2015 | β |
| Identification of Wnt Pathway Target Genes Regulating the Division and Differentiation of Larval Seam Cells and Vulval Precursor Cells in Caenorhabditis elegans. | Gorrepati L et al. | β | 2015 | β |
| Inactivated E. coli transformed with plasmids that produce dsRNA against infectious salmon anemia virus hemagglutinin show antiviral activity when added to infected ASK cells. | GarcΓa K et al. | β | 2015 | β |
| Isolation of a Hypomorphic skn-1 Allele That Does Not Require a Balancer for Maintenance. | Tang L et al. | β | 2015 | β |
| KLP-7 acts through the Ndc80 complex to limit pole number in C. elegans oocyte meiotic spindle assembly. | Connolly AA et al. | β | 2015 | β |
| Lipid-mediated regulation of SKN-1/Nrf in response to germ cell absence. | Steinbaugh MJ et al. | β | 2015 | β |
| Longevity Genes Revealed by Integrative Analysis of Isoform-Specific daf-16/FoxO Mutants of Caenorhabditis elegans. | Chen AT et al. | β | 2015 | β |
| MED GATA factors promote robust development of the C. elegans endoderm. | Maduro MF et al. | β | 2015 | β |
| Oriented Cell Division in the C. elegans Embryo Is Coordinated by G-Protein Signaling Dependent on the Adhesion GPCR LAT-1. | MΓΌller A et al. | β | 2015 | β |
| pxn-1 and pxn-2 May Interact Negatively during Neuronal Development and Aging in C. elegans. | Cho I et al. | β | 2015 | β |
| Quantitative analysis and modeling probe polarity establishment in C. elegans embryos. | Blanchoud S et al. | β | 2015 | β |
| Rapid and precise engineering of the Caenorhabditis elegans genome with lethal mutation co-conversion and inactivation of NHEJ repair. | Ward JD | β | 2015 | β |
| Rapid Increase in frequency of gene copy-number variants during experimental evolution in Caenorhabditis elegans. | Farslow JC et al. | β | 2015 | β |
| RNA Interference in Caenorhabditis elegans. | Conte D et al. | β | 2015 | β |
| Robust Distal Tip Cell Pathfinding in the Face of Temperature Stress Is Ensured by Two Conserved microRNAS in Caenorhabditis elegans. | Burke SL et al. | β | 2015 | β |
| The asymmetry of female meiosis reduces the frequency of inheritance of unpaired chromosomes. | Cortes DB et al. | β | 2015 | β |
| The Causative Gene in Chanarian Dorfman Syndrome Regulates Lipid Droplet Homeostasis in C. elegans. | Xie M et al. | β | 2015 | β |
| The C. elegans Chp/Wrch Ortholog CHW-1 Contributes to LIN-18/Ryk and LIN-17/Frizzled Signaling in Cell Polarity. | Kidd AR et al. | β | 2015 | β |
| The GATA factor elt-1 regulates C. elegans developmental timing by promoting expression of the let-7 family microRNAs. | Cohen ML et al. | β | 2015 | β |
| The KLP-7 Residue S546 Is a Putative Aurora Kinase Site Required for Microtubule Regulation at the Centrosome in C. elegans. | Han X et al. | β | 2015 | β |
| The Tumor Suppressor BCL7B Functions in the Wnt Signaling Pathway. | Uehara T et al. | β | 2015 | β |
| The Wnt Frizzled Receptor MOM-5 Regulates the UNC-5 Netrin Receptor through Small GTPase-Dependent Signaling to Determine the Polarity of Migrating Cells. | Levy-Strumpf N et al. | β | 2015 | β |
| WormGender - Open-Source Software for Automatic Caenorhabditis elegans Sex Ratio Measurement. | Labocha MK et al. | β | 2015 | β |
| A conditional knockout toolkit for Caenorhabditis elegans based on the Cre/loxP recombination. | Kage-Nakadai E et al. | β | 2014 | β |
| Activated and inactivated immune responses in Caenorhabditis elegans against Photorhabdus luminescens TT01. | Sato K et al. | β | 2014 | β |
| An AGEF-1/Arf GTPase/AP-1 ensemble antagonizes LET-23 EGFR basolateral localization and signaling during C. elegans vulva induction. | Skorobogata O et al. | β | 2014 | β |
| A protocol to infect Caenorhabditis elegans with Salmonella typhimurium. | Zhang J et al. | β | 2014 | β |
| Asymmetric neuroblast divisions producing apoptotic cells require the cytohesin GRP-1 in Caenorhabditis elegans. | Teuliere J et al. | β | 2014 | β |
| A systematic analysis of protein palmitoylation in Caenorhabditis elegans. | Edmonds MJ et al. | β | 2014 | β |
| BLMP-1/Blimp-1 regulates the spatiotemporal cell migration pattern in C. elegans. | Huang TF et al. | β | 2014 | β |
| Caenorhabditis elegans HOPS and CCZ-1 mediate trafficking to lysosome-related organelles independently of RAB-7 and SAND-1. | Delahaye JL et al. | β | 2014 | β |
| Caenorhabditis elegans oocyte meiotic spindle pole assembly requires microtubule severing and the calponin homology domain protein ASPM-1. | Connolly AA et al. | β | 2014 | β |
| Caenorhabditis elegans RSD-2 and RSD-6 promote germ cell immortality by maintaining small interfering RNA populations. | Sakaguchi A et al. | β | 2014 | β |
| C. elegans Anillin proteins regulate intercellular bridge stability and germline syncytial organization. | Amini R et al. | β | 2014 | β |
| Comparative RNAi screens in C. elegans and C. briggsae reveal the impact of developmental system drift on gene function. | Verster AJ et al. | β | 2014 | β |
| daf-31 encodes the catalytic subunit of N alpha-acetyltransferase that regulates Caenorhabditis elegans development, metabolism and adult lifespan. | Chen D et al. | β | 2014 | β |
| Defects in the C. elegans acyl-CoA synthase, acs-3, and nuclear hormone receptor, nhr-25, cause sensitivity to distinct, but overlapping stresses. | Ward JD et al. | β | 2014 | β |
| Diverse functions of mRNA metabolism factors in stress defense and aging of Caenorhabditis elegans. | Rousakis A et al. | β | 2014 | β |
| Dopamine signaling regulates fat content through Ξ²-oxidation in Caenorhabditis elegans. | Barros AG et al. | β | 2014 | β |
| Engineering of a conditional allele reveals multiple roles of XRN2 in Caenorhabditis elegans development and substrate specificity in microRNA turnover. | Miki TS et al. | β | 2014 | β |
| Enterococcus infection biology: lessons from invertebrate host models. | Yuen GJ et al. | β | 2014 | β |
| Family of FLP Peptides in Caenorhabditis elegans and Related Nematodes. | Li C et al. | β | 2014 | β |
| Folliculin regulates ampk-dependent autophagy and metabolic stress survival. | Possik E et al. | β | 2014 | β |
| Function of the Ryk intracellular domain in C. elegans vulval development. | Poh WC et al. | β | 2014 | β |
| Genetic analysis of a novel tubulin mutation that redirects synaptic vesicle targeting and causes neurite degeneration in C. elegans. | Hsu JM et al. | β | 2014 | β |
| Genetic screens in Caenorhabditis elegans models for neurodegenerative diseases. | Sin O et al. | β | 2014 | β |
| Identification of a genetic interaction between the tumor suppressor EAF2 and the retinoblastoma protein (Rb) signaling pathway in C. elegans and prostate cancer cells. | Cai L et al. | β | 2014 | β |
| Identification of genes in toxicity pathways of trinucleotide-repeat RNA in C. elegans. | Garcia SM et al. | β | 2014 | β |
| In situ imaging in C. elegans reveals developmental regulation of microtubule dynamics. | Lacroix B et al. | β | 2014 | β |
| Katanin maintains meiotic metaphase chromosome alignment and spindle structure in vivo and has multiple effects on microtubules in vitro. | McNally K et al. | β | 2014 | β |
| Ku-mediated coupling of DNA cleavage and repair during programmed genome rearrangements in the ciliate Paramecium tetraurelia. | Marmignon A et al. | β | 2014 | β |
| LET-418/Mi2 and SPR-5/LSD1 cooperatively prevent somatic reprogramming of C. elegans germline stem cells. | KΓ€ser-PΓ©bernard S et al. | β | 2014 | β |
| Light and pheromone-sensing neurons regulates cold habituation through insulin signalling in Caenorhabditis elegans. | Ohta A et al. | β | 2014 | β |
| LINKIN, a new transmembrane protein necessary for cell adhesion. | Kato M et al. | β | 2014 | β |
| Loss of Sirt1 function improves intestinal anti-bacterial defense and protects from colitis-induced colorectal cancer. | Lo Sasso G et al. | β | 2014 | β |
| MIG-10 (Lamellipodin) stabilizes invading cell adhesion to basement membrane and is a negative transcriptional target of EGL-43 in C. elegans. | Wang L et al. | β | 2014 | β |
| Mutations in conserved residues of the C. elegans microRNA Argonaute ALG-1 identify separable functions in ALG-1 miRISC loading and target repression. | Zinovyeva AY et al. | β | 2014 | β |
| Noncanonical cell death in the nematode Caenorhabditis elegans. | Kinet MJ et al. | β | 2014 | β |
| NRA-2, a nicalin homolog, regulates neuronal death by controlling surface localization of toxic Caenorhabditis elegans DEG/ENaC channels. | Kamat S et al. | β | 2014 | β |
| Oral delivery mediated RNA interference of a carboxylesterase gene results in reduced resistance to organophosphorus insecticides in the cotton Aphid, Aphis gossypii Glover. | Gong YH et al. | β | 2014 | β |
| PAR-4/LKB1 regulates DNA replication during asynchronous division of the early C. elegans embryo. | Benkemoun L et al. | β | 2014 | β |
| Phospholipids that contain polyunsaturated fatty acids enhance neuronal cell mechanics and touch sensation. | VΓ‘squez V et al. | β | 2014 | β |
| Repurposing an endogenous degradation system for rapid and targeted depletion of C. elegans proteins. | Armenti ST et al. | β | 2014 | β |
| Searching for the elusive mitochondrial longevity signal in C. elegans. | Bennett CF et al. | β | 2014 | β |
| Selenite protects Caenorhabditis elegans from oxidative stress via DAF-16 and TRXR-1. | Li WH et al. | β | 2014 | β |
| The Anaphase-Promoting Complex (APC) ubiquitin ligase regulates GABA transmission at the C. elegans neuromuscular junction. | Kowalski JR et al. | β | 2014 | β |
| The Caenorhabditis elegans pericentriolar material components SPD-2 and SPD-5 are monomeric in the cytoplasm before incorporation into the PCM matrix. | Wueseke O et al. | β | 2014 | β |
| The DAF-16 FOXO transcription factor regulates natc-1 to modulate stress resistance in Caenorhabditis elegans, linking insulin/IGF-1 signaling to protein N-terminal acetylation. | Warnhoff K et al. | β | 2014 | β |
| The new world of RNAs. | Dogini DB et al. | β | 2014 | β |
| The nucleotide-binding proteins Nubp1 and Nubp2 are negative regulators of ciliogenesis. | Kypri E et al. | β | 2014 | β |
| The zinc matrix metalloproteinase ZMP-2 increases survival of Caenorhabditis elegans through interference with lipoprotein absorption. | Fischer M et al. | β | 2014 | β |
| UNC-6 (netrin) stabilizes oscillatory clustering of the UNC-40 (DCC) receptor to orient polarity. | Wang Z et al. | β | 2014 | β |
| Use of an activated beta-catenin to identify Wnt pathway target genes in caenorhabditis elegans, including a subset of collagen genes expressed in late larval development. | Jackson BM et al. | β | 2014 | β |
| Abelson interactor-1 (ABI-1) interacts with MRL adaptor protein MIG-10 and is required in guided cell migrations and process outgrowth in C. elegans. | McShea MA et al. | β | 2013 | β |
| A common copy number variation (CNV) polymorphism in the CNTNAP4 gene: association with aging in females. | Iakoubov L et al. | β | 2013 | β |
| Adaptive and specialised transcriptional responses to xenobiotic stress in Caenorhabditis elegans are regulated by nuclear hormone receptors. | Jones LM et al. | β | 2013 | β |
| A DNA synthesis inhibitor is protective against proteotoxic stressors via modulation of fertility pathways in Caenorhabditis elegans. | Angeli S et al. | β | 2013 | β |
| A negative-feedback loop between the detoxification/antioxidant response factor SKN-1 and its repressor WDR-23 matches organism needs with environmental conditions. | Leung CK et al. | β | 2013 | β |
| A novel interaction between aging and ER overload in a protein conformational dementia. | Schipanski A et al. | β | 2013 | β |
| Anthranilate fluorescence marks a calcium-propagated necrotic wave that promotes organismal death in C. elegans. | Coburn C et al. | β | 2013 | β |
| Applications of RNA Interference in Schistosomiasis: Gene Function Identification and Development of New Therapies. | Pereira TC et al. | β | 2013 | β |
| Arl8/ARL-8 functions in apoptotic cell removal by mediating phagolysosome formation in Caenorhabditis elegans. | Sasaki A et al. | β | 2013 | β |
| Caenorhabditis elegans PIG-1/MELK acts in a conserved PAR-4/LKB1 polarity pathway to promote asymmetric neuroblast divisions. | Chien SC et al. | β | 2013 | β |
| C. elegans Rassf homolog, rasf-1, is functionally associated with rab-39 Rab GTPase in oxidative stress response. | Takenaka M et al. | β | 2013 | β |
| CRL2(LRR-1) E3-ligase regulates proliferation and progression through meiosis in the Caenorhabditis elegans germline. | Burger J et al. | β | 2013 | β |
| Deficiency of Ξ±-glucosidase I alters glycoprotein glycosylation and lifespan in Caenorhabditis elegans. | Katoh T et al. | β | 2013 | β |
| Delivery of dsRNA for RNAi in insects: an overview and future directions. | Yu N et al. | β | 2013 | β |
| Depletion of the ER chaperone ENPL-1 sensitizes C. elegans to the anticancer drug cisplatin. | Natarajan B et al. | β | 2013 | β |
| Development of an RNAi based microalgal larvicide to control mosquitoes. | Kumar A et al. | β | 2013 | β |
| Disorders of protein misfolding: alpha-1-antitrypsin deficiency as prototype. | Silverman GA et al. | β | 2013 | β |
| Extrasynaptic muscarinic acetylcholine receptors on neuronal cell bodies regulate presynaptic function in Caenorhabditis elegans. | Chan JP et al. | β | 2013 | β |
| Function of the C. elegans T-box factor TBX-2 depends on SUMOylation. | Huber P et al. | β | 2013 | β |
| Haploinsufficiency of akt1 prolongs the lifespan of mice. | Nojima A et al. | β | 2013 | β |
| Invertebrate models of dystonia. | Caldwell KA et al. | β | 2013 | β |
| Large-scale gene knockdown in C. elegans using dsRNA feeding libraries to generate robust loss-of-function phenotypes. | Maher KN et al. | β | 2013 | β |
| Matefin/SUN-1 phosphorylation is part of a surveillance mechanism to coordinate chromosome synapsis and recombination with meiotic progression and chromosome movement. | Woglar A et al. | β | 2013 | β |
| Metformin retards aging in C. elegans by altering microbial folate and methionine metabolism. | Cabreiro F et al. | β | 2013 | β |
| Microtubule severing by the katanin complex is activated by PPFR-1-dependent MEI-1 dephosphorylation. | Gomes JE et al. | β | 2013 | β |
| Molecular strategies of the Caenorhabditis elegans dauer larva to survive extreme desiccation. | Erkut C et al. | β | 2013 | β |
| Multiparameter behavioral analyses provide insights to mechanisms of cyanide resistance in Caenorhabditis elegans. | Saldanha JN et al. | β | 2013 | β |
| Neuron-specific feeding RNAi in C. elegans and its use in a screen for essential genes required for GABA neuron function. | Firnhaber C et al. | β | 2013 | β |
| N-glycosylation is required for secretion and mitosis in C. elegans. | Stevens J et al. | β | 2013 | β |
| Noncanonical control of C. elegans germline apoptosis by the insulin/IGF-1 and Ras/MAPK signaling pathways. | Perrin AJ et al. | β | 2013 | β |
| Prolyl 4-hydroxlase activity is essential for development and cuticle formation in the human infective parasitic nematode Brugia malayi. | Winter AD et al. | β | 2013 | β |
| Redundant canonical and noncanonical Caenorhabditis elegans p21-activated kinase signaling governs distal tip cell migrations. | Peters EC et al. | β | 2013 | β |
| Regulation of the CRL4(Cdt2) ubiquitin ligase and cell-cycle exit by the SCF(Fbxo11) ubiquitin ligase. | Rossi M et al. | β | 2013 | β |
| Silencing the HaHR3 gene by transgenic plant-mediated RNAi to disrupt Helicoverpa armigera development. | Xiong Y et al. | β | 2013 | β |
| Succinate dehydrogenase upregulation destabilize complex I and limits the lifespan of gas-1 mutant. | Pujol C et al. | β | 2013 | β |
| Synapse location during growth depends on glia location. | Shao Z et al. | β | 2013 | β |
| The C. elegans gene pan-1 encodes novel transmembrane and cytoplasmic leucine-rich repeat proteins and promotes molting and the larva to adult transition. | Gissendanner CR et al. | β | 2013 | β |
| The E3 ubiquitin ligase mind bomb 1 ubiquitinates and promotes the degradation of survival of motor neuron protein. | Kwon DY et al. | β | 2013 | β |
| TORC2 signaling antagonizes SKN-1 to induce C. elegans mesendodermal embryonic development. | Ruf V et al. | β | 2013 | β |
| Unexpected role for dosage compensation in the control of dauer arrest, insulin-like signaling, and FoxO transcription factor activity in Caenorhabditis elegans. | Dumas KJ et al. | β | 2013 | β |
| A directed RNAi screen based on larval growth arrest reveals new modifiers of C. elegans insulin signaling. | Billing O et al. | β | 2012 | β |
| APL-1, the Alzheimer's Amyloid precursor protein in Caenorhabditis elegans, modulates multiple metabolic pathways throughout development. | Ewald CY et al. | β | 2012 | β |
| A steroid receptor-microRNA switch regulates life span in response to signals from the gonad. | Shen Y et al. | β | 2012 | β |
| C. elegans BLOC-1 functions in trafficking to lysosome-related gut granules. | Hermann GJ et al. | β | 2012 | β |
| C. elegans dopaminergic D2-like receptors delimit recurrent cholinergic-mediated motor programs during a goal-oriented behavior. | Correa P et al. | β | 2012 | β |
| C. elegans EIF-3.K promotes programmed cell death through CED-3 caspase. | Huang CY et al. | β | 2012 | β |
| C. elegans VANG-1 modulates life span via insulin/IGF-1-like signaling. | Honnen SJ et al. | β | 2012 | β |
| Cell-cycle regulation of NOTCH signaling during C. elegans vulval development. | Nusser-Stein S et al. | β | 2012 | β |
| CSR-1 RNAi pathway positively regulates histone expression in C. elegans. | Avgousti DC et al. | β | 2012 | β |
| CUP-1 is a novel protein involved in dietary cholesterol uptake in Caenorhabditis elegans. | Valdes VJ et al. | β | 2012 | β |
| Depletion of mboa-7, an enzyme that incorporates polyunsaturated fatty acids into phosphatidylinositol (PI), impairs PI 3-phosphate signaling in Caenorhabditis elegans. | Lee HC et al. | β | 2012 | β |
| Distinct Caenorhabditis elegans HLH-8/twist-containing dimers function in the mesoderm. | Philogene MC et al. | β | 2012 | β |
| Distinct cell guidance pathways controlled by the Rac and Rho GEF domains of UNC-73/TRIO in Caenorhabditis elegans. | Marcus-Gueret N et al. | β | 2012 | β |
| Endocytosis and intracellular trafficking contribute to necrotic neurodegeneration in C. elegans. | Troulinaki K et al. | β | 2012 | β |
| Ethanol metabolism and osmolarity modify behavioral responses to ethanol in C. elegans. | Alaimo JT et al. | β | 2012 | β |
| From genes to function: the C. elegans genetic toolbox. | Boulin T et al. | β | 2012 | β |
| Genome-Wide RNAi Longevity Screens in Caenorhabditis elegans. | Yanos ME et al. | β | 2012 | β |
| Identification of intermediate-size non-coding RNAs involved in the UV-induced DNA damage response in C. elegans. | Li A et al. | β | 2012 | β |
| Identification of novel genes involved in sarcopenia through RNAi screening in Caenorhabditis elegans. | Kashyap L et al. | β | 2012 | β |
| Lipid droplets as fat storage organelles in Caenorhabditis elegans: Thematic Review Series: Lipid Droplet Synthesis and Metabolism: from Yeast to Man. | Mak HY | β | 2012 | β |
| Manipulation of in vivo iron levels can alter resistance to oxidative stress without affecting ageing in the nematode C. elegans. | Valentini S et al. | β | 2012 | β |
| Midlife gene expressions identify modulators of aging through dietary interventions. | Zhou B et al. | β | 2012 | β |
| Muscle-specific splicing factors ASD-2 and SUP-12 cooperatively switch alternative pre-mRNA processing patterns of the ADF/cofilin gene in Caenorhabditis elegans. | Ohno G et al. | β | 2012 | β |
| Quantitative proteomics by amino acid labeling identifies novel NHR-49 regulated proteins in C. elegans. | Fredens J et al. | β | 2012 | β |
| RAB-7 antagonizes LET-23 EGFR signaling during vulva development in Caenorhabditis elegans. | Skorobogata O et al. | β | 2012 | β |
| Reduction of mitoferrin results in abnormal development and extended lifespan in Caenorhabditis elegans. | Ren Y et al. | β | 2012 | β |
| Regulation of maternal phospholipid composition and IP(3)-dependent embryonic membrane dynamics by a specific fatty acid metabolic event in C. elegans. | Kniazeva M et al. | β | 2012 | β |
| Regulation of neuronal APL-1 expression by cholesterol starvation. | Wiese M et al. | β | 2012 | β |
| SLI-1 Cbl inhibits the engulfment of apoptotic cells in C. elegans through a ligase-independent function. | Anderson C et al. | β | 2012 | β |
| TBC-8, a putative RAB-2 GAP, regulates dense core vesicle maturation in Caenorhabditis elegans. | Hannemann M et al. | β | 2012 | β |
| The effect of environmental conditions on biofilm formation of Burkholderia pseudomallei clinical isolates. | Ramli NS et al. | β | 2012 | β |
| The growth factor SVH-1 regulates axon regeneration in C. elegans via the JNK MAPK cascade. | Li C et al. | β | 2012 | β |
| The novel intestinal filament organizer IFO-1 contributes to epithelial integrity in concert with ERM-1 and DLG-1. | Carberry K et al. | β | 2012 | β |
| Two PI 3-kinases and one PI 3-phosphatase together establish the cyclic waves of phagosomal PtdIns(3)P critical for the degradation of apoptotic cells. | Lu N et al. | β | 2012 | β |
| Vampiric isolation of extracellular fluid from Caenorhabditis elegans. | Banse SA et al. | β | 2012 | β |
| (1)H NMR-based metabolic profiling reveals inherent biological variation in yeast and nematode model systems. | Szeto SS et al. | β | 2011 | β |
| A cholinergic-regulated circuit coordinates the maintenance and bi-stable states of a sensory-motor behavior during Caenorhabditis elegans male copulation. | Liu Y et al. | β | 2011 | β |
| A glutathione peroxidase, intracellular peptidases and the TOR complexes regulate peptide transporter PEPT-1 in C. elegans. | Benner J et al. | β | 2011 | β |
| A phagocytic route for uptake of double-stranded RNA in RNAi. | Rocha JJ et al. | β | 2011 | β |
| Autophagy machinery mediates macroendocytic processing and entotic cell death by targeting single membranes. | Florey O et al. | β | 2011 | β |
| CDC-48/p97 coordinates CDT-1 degradation with GINS chromatin dissociation to ensure faithful DNA replication. | Franz A et al. | β | 2011 | β |
| CDK-1 inhibits meiotic spindle shortening and dynein-dependent spindle rotation in C. elegans. | Ellefson ML et al. | β | 2011 | β |
| C. elegans ADAMTS ADT-2 regulates body size by modulating TGFΞ² signaling and cuticle collagen organization. | Fernando T et al. | β | 2011 | β |
| Complete killing of Caenorhabditis elegans by Burkholderia pseudomallei is dependent on prolonged direct association with the viable pathogen. | Lee SH et al. | β | 2011 | β |
| Evolution of embryonic development in nematodes. | Schulze J et al. | β | 2011 | β |
| Galectin LEC-6 interacts with glycoprotein F57F4.4 to cooperatively regulate the growth of Caenorhabditis elegans. | Takeuchi T et al. | β | 2011 | β |
| Global functional analyses of cellular responses to pore-forming toxins. | Kao CY et al. | β | 2011 | β |
| Hox and a newly identified E2F co-repress cell death in Caenorhabditis elegans. | Winn J et al. | β | 2011 | β |
| Life span extension via eIF4G inhibition is mediated by posttranscriptional remodeling of stress response gene expression in C. elegans. | Rogers AN et al. | β | 2011 | β |
| MISC-1/OGC links mitochondrial metabolism, apoptosis and insulin secretion. | Gallo M et al. | β | 2011 | β |
| Mitochondrial function is required for secretion of DAF-28/insulin in C. elegans. | Billing O et al. | β | 2011 | β |
| Molecular and biochemical analysis of the Ξ± class carbonic anhydrases in Caenorhabditis elegans. | Fasseas MK et al. | β | 2011 | β |
| Multiple phenotypes resulting from a mutagenesis screen for pharynx muscle mutations in Caenorhabditis elegans. | Ferrier A et al. | β | 2011 | β |
| Overcoming redundancy: an RNAi enhancer screen for morphogenesis genes in Caenorhabditis elegans. | Sawyer JM et al. | β | 2011 | β |
| Ras effector switching promotes divergent cell fates in C. elegans vulval patterning. | Zand TP et al. | β | 2011 | β |
| Regulation of fertility, survival, and cuticle collagen function by the Caenorhabditis elegans eaf-1 and ell-1 genes. | Cai L et al. | β | 2011 | β |
| Stable-isotope labeling with amino acids in nematodes. | Larance M et al. | β | 2011 | β |
| The Caenorhabditis elegans GARP complex contains the conserved Vps51 subunit and is required to maintain lysosomal morphology. | Luo L et al. | β | 2011 | β |
| The Caenorhabditis elegans T-box factor MLS-1 requires Groucho co-repressor interaction for uterine muscle specification. | Miller RR et al. | β | 2011 | β |
| The interplay between protein L-isoaspartyl methyltransferase activity and insulin-like signaling to extend lifespan in Caenorhabditis elegans. | Khare S et al. | β | 2011 | β |
| The LIN-15A and LIN-56 transcriptional regulators interact to negatively regulate EGF/Ras signaling in Caenorhabditis elegans vulval cell-fate determination. | Davison EM et al. | β | 2011 | β |
| The two-component sensor kinase KdpD is required for Salmonella typhimurium colonization of Caenorhabditis elegans and survival in macrophages. | Alegado RA et al. | β | 2011 | β |
| Three sorting nexins drive the degradation of apoptotic cells in response to PtdIns(3)P signaling. | Lu N et al. | β | 2011 | β |
| TRPM channels modulate epileptic-like convulsions via systemic ion homeostasis. | Stawicki TM et al. | β | 2011 | β |
| Using C. elegans to identify the protease targets of serpins in vivo. | Bhatia SR et al. | β | 2011 | β |
| A C. elegans eIF4E-family member upregulates translation at elevated temperatures of mRNAs encoding MSH-5 and other meiotic crossover proteins. | Song A et al. | β | 2010 | β |
| Allyl isothiocyanate that induces GST and UGT expression confers oxidative stress resistance on C. elegans, as demonstrated by nematode biosensor. | Hasegawa K et al. | β | 2010 | β |
| Arrestin and the multi-PDZ domain-containing protein MPZ-1 interact with phosphatase and tensin homolog (PTEN) and regulate Caenorhabditis elegans longevity. | Palmitessa A et al. | β | 2010 | β |
| Bacteria, yeast, worms, and flies: exploiting simple model organisms to investigate human mitochondrial diseases. | Rea SL et al. | β | 2010 | β |
| Bioinformatic and biochemical studies point to AAGR-1 as the ortholog of human acid alpha-glucosidase in Caenorhabditis elegans. | Sikora J et al. | β | 2010 | β |
| Caenorhabditis elegans bicarbonate transporter ABTS-1 is involved in arsenite toxicity and cholinergic signaling. | Liao VH et al. | β | 2010 | β |
| Caloric restriction and resveratrol promote longevity through the Sirtuin-1-dependent induction of autophagy. | Morselli E et al. | β | 2010 | β |
| C. elegans twist gene expression in differentiated cell types is controlled by autoregulation through intron elements. | Meyers SG et al. | β | 2010 | β |
| Conserved genes act as modifiers of invertebrate SMN loss of function defects. | Dimitriadi M et al. | β | 2010 | β |
| Development of an in vivo RNAi protocol to investigate gene function in the filarial nematode, Brugia malayi. | Song C et al. | β | 2010 | β |
| ETS-4 is a transcriptional regulator of life span in Caenorhabditis elegans. | Thyagarajan B et al. | β | 2010 | β |
| Expression and functional characterization of a Rho-family small GTPase CDC42 from Trichinella spiralis. | Yang Y et al. | β | 2010 | β |
| Genetic and cellular characterization of Caenorhabditis elegans mutants abnormal in the regulation of many phase II enzymes. | Hasegawa K et al. | β | 2010 | β |
| Genetics of extracellular matrix remodeling during organ growth using the Caenorhabditis elegans pharynx model. | Jafari G et al. | β | 2010 | β |
| HSF1-controlled and age-associated chaperone capacity in neurons and muscle cells of C. elegans. | Kern A et al. | β | 2010 | β |
| Intracellular trafficking and synaptic function of APL-1 in Caenorhabditis elegans. | Wiese M et al. | β | 2010 | β |
| mab-31 and the TGF-beta pathway act in the ray lineage to pattern C. elegans male sensory rays. | Wong YF et al. | β | 2010 | β |
| Magnesium excretion in C. elegans requires the activity of the GTL-2 TRPM channel. | Teramoto T et al. | β | 2010 | β |
| Mitochondrial fragmentation leads to intracellular acidification in Caenorhabditis elegans and mammalian cells. | Johnson D et al. | β | 2010 | β |
| MKK6 binds and regulates expression of Parkinson's disease-related protein LRRK2. | Hsu CH et al. | β | 2010 | β |
| Molecular and biochemical analysis of the beta class carbonic anhydrases in Caenorhabditis elegans. | Fasseas MK et al. | β | 2010 | β |
| Molecular characterization and RNA interference of three midgut aminopeptidase N isozymes from Bacillus thuringiensis-susceptible and -resistant strains of sugarcane borer, Diatraea saccharalis. | Yang Y et al. | β | 2010 | β |
| Multivesicular body formation requires OSBP-related proteins and cholesterol. | Kobuna H et al. | β | 2010 | β |
| Nuclear pre-mRNA 3'-end processing regulates synapse and axon development in C. elegans. | Van Epps H et al. | β | 2010 | β |
| PAR-3 mediates the initial clustering and apical localization of junction and polarity proteins during C. elegans intestinal epithelial cell polarization. | Achilleos A et al. | β | 2010 | β |
| Protein homeostasis in models of aging and age-related conformational disease. | Kikis EA et al. | β | 2010 | β |
| Regulation of cortical contractility and spindle positioning by the protein phosphatase 6 PPH-6 in one-cell stage C. elegans embryos. | Afshar K et al. | β | 2010 | β |
| RNA interference as a gene knockdown technique. | Shan G | β | 2010 | β |
| RNAi screening implicates a SKN-1-dependent transcriptional response in stress resistance and longevity deriving from translation inhibition. | Wang J et al. | β | 2010 | β |
| RNAi screens to identify components of gene networks that modulate aging in Caenorhabditis elegans. | Ni Z et al. | β | 2010 | β |
| Specific roles for DEG/ENaC and TRP channels in touch and thermosensation in C. elegans nociceptors. | Chatzigeorgiou M et al. | β | 2010 | β |
| TBC-2 regulates RAB-5/RAB-7-mediated endosomal trafficking in Caenorhabditis elegans. | Chotard L et al. | β | 2010 | β |
| The arf-like GTPase Arl8 mediates delivery of endocytosed macromolecules to lysosomes in Caenorhabditis elegans. | Nakae I et al. | β | 2010 | β |
| The C. elegans developmental timing protein LIN-42 regulates diapause in response to environmental cues. | Tennessen JM et al. | β | 2010 | β |
| The conserved mitochondrial twin Cx9C protein Cmc2 Is a Cmc1 homologue essential for cytochrome c oxidase biogenesis. | Horn D et al. | β | 2010 | β |
| The CRL2LRR-1 ubiquitin ligase regulates cell cycle progression during C. elegans development. | Merlet J et al. | β | 2010 | β |
| The DM domain transcription factor MAB-3 regulates male hypersensitivity to oxidative stress in Caenorhabditis elegans. | Inoue H et al. | β | 2010 | β |
| The ERK-MAPK pathway regulates longevity through SKN-1 and insulin-like signaling in Caenorhabditis elegans. | Okuyama T et al. | β | 2010 | β |
| UNC-64 and RIC-4, the plasma membrane-associated SNAREs syntaxin and SNAP-25, regulate fat storage in nematode Caenorhabditis elegans. | Wu QL et al. | β | 2010 | β |
| Abl kinase inhibits the engulfment of apoptotic [corrected] cells in Caenorhabditis elegans. | Hurwitz ME et al. | β | 2009 | β |
| A C. elegans LSD1 demethylase contributes to germline immortality by reprogramming epigenetic memory. | Katz DJ et al. | β | 2009 | β |
| A cell cycle timer for asymmetric spindle positioning. | McCarthy Campbell EK et al. | β | 2009 | β |
| Adaptive sugar provisioning controls survival of C. elegans embryos in adverse environments. | Frazier HN et al. | β | 2009 | β |
| A genomewide RNAi screen for genes that affect the stability, distribution and function of P granules in Caenorhabditis elegans. | Updike DL et al. | β | 2009 | β |
| A human protein interaction network shows conservation of aging processes between human and invertebrate species. | Bell R et al. | β | 2009 | β |
| Autophagy genes protect against Salmonella typhimurium infection and mediate insulin signaling-regulated pathogen resistance. | Jia K et al. | β | 2009 | β |
| Caenorhabditis elegans FOS-1 and JUN-1 regulate plc-1 expression in the spermatheca to control ovulation. | Hiatt SM et al. | β | 2009 | β |
| Ce-Duox1/BLI-3 generates reactive oxygen species as a protective innate immune mechanism in Caenorhabditis elegans. | ChΓ‘vez V et al. | β | 2009 | β |
| C. elegans ATAD-3 is essential for mitochondrial activity and development. | Hoffmann M et al. | β | 2009 | β |
| C. elegans CARMIL negatively regulates UNC-73/Trio function during neuronal development. | Vanderzalm PJ et al. | β | 2009 | β |
| C. elegans RNAi space experiment (CERISE) in Japanese Experiment Module KIBO. | Higashitani A et al. | β | 2009 | β |
| Condition-adapted stress and longevity gene regulation by Caenorhabditis elegans SKN-1/Nrf. | Oliveira RP et al. | β | 2009 | β |
| Developmental control of a lepidopteran pest Spodoptera exigua by ingestion of bacteria expressing dsRNA of a non-midgut gene. | Tian H et al. | β | 2009 | β |
| Evolution of early embryogenesis in rhabditid nematodes. | Brauchle M et al. | β | 2009 | β |
| Fast, automated measurement of nematode swimming (thrashing) without morphometry. | Buckingham SD et al. | β | 2009 | β |
| Feeding a ROS-generator to Caenorhabditis elegans leads to increased expression of small heat shock protein HSP-16.2 and hormesis. | Hartwig K et al. | β | 2009 | β |
| Genetic dissection of Caenorhabditis elegans embryogenesis using RNA interference and flow cytometry. | Boulier EL et al. | β | 2009 | β |
| How the intestinal peptide transporter PEPT-1 contributes to an obesity phenotype in Caenorhabditits elegans. | Spanier B et al. | β | 2009 | β |
| Impact of cigarette smoke exposure on innate immunity: a Caenorhabditis elegans model. | Green RM et al. | β | 2009 | β |
| Kinesin-1 and cytoplasmic dynein act sequentially to move the meiotic spindle to the oocyte cortex in Caenorhabditis elegans. | Ellefson ML et al. | β | 2009 | β |
| Lifespan extension by suppression of autophagy genes in Caenorhabditis elegans. | Hashimoto Y et al. | β | 2009 | β |
| LRRK2 modulates vulnerability to mitochondrial dysfunction in Caenorhabditis elegans. | Saha S et al. | β | 2009 | β |
| MAGI-1 modulates AMPA receptor synaptic localization and behavioral plasticity in response to prior experience. | Emtage L et al. | β | 2009 | β |
| Mitochondrial DNA level, but not active replicase, is essential for Caenorhabditis elegans development. | Bratic I et al. | β | 2009 | β |
| Modeling a congenital disorder of glycosylation type I in C. elegans: a genome-wide RNAi screen for N-glycosylation-dependent loci. | Struwe WB et al. | β | 2009 | β |
| P-type ATPase TAT-2 negatively regulates monomethyl branched-chain fatty acid mediated function in post-embryonic growth and development in C. elegans. | Seamen E et al. | β | 2009 | β |
| Quantitative high-throughput analysis of synthetic genetic interactions in Caenorhabditis elegans by RNA interference. | Fortunato A | β | 2009 | β |
| Reduction in ovulation or male sex phenotype increases long-term anoxia survival in a daf-16-independent manner in Caenorhabditis elegans. | Mendenhall AR et al. | β | 2009 | β |
| Regulation of transcription termination in the nematode Caenorhabditis elegans. | Haenni S et al. | β | 2009 | β |
| RNA interference-mediated knockdown of a cytochrome P450, CYP6BG1, from the diamondback moth, Plutella xylostella, reduces larval resistance to permethrin. | Bautista MA et al. | β | 2009 | β |
| Signalling through RHEB-1 mediates intermittent fasting-induced longevity in C. elegans. | Honjoh S et al. | β | 2009 | β |
| The ALP-Enigma protein ALP-1 functions in actin filament organization to promote muscle structural integrity in Caenorhabditis elegans. | Han HF et al. | β | 2009 | β |
| The C. elegans tailless/Tlx homolog nhr-67 regulates a stage-specific program of linker cell migration in male gonadogenesis. | Kato M et al. | β | 2009 | β |
| UNC-108/RAB-2 and its effector RIC-19 are involved in dense core vesicle maturation in Caenorhabditis elegans. | Sumakovic M et al. | β | 2009 | β |
| Wnt and EGF pathways act together to induce C. elegans male hook development. | Yu H et al. | β | 2009 | β |
| A branched-chain fatty acid is involved in post-embryonic growth control in parallel to the insulin receptor pathway and its biosynthesis is feedback-regulated in C. elegans. | Kniazeva M et al. | β | 2008 | β |
| A microcosm of the biomedical research experience for upper-level undergraduates. | Hurd DD | β | 2008 | β |
| A novel role for the SMG-1 kinase in lifespan and oxidative stress resistance in Caenorhabditis elegans. | Masse I et al. | β | 2008 | β |
| An unexpectedly high degree of specialization and a widespread involvement in sterol metabolism among the C. elegans putative aminophospholipid translocases. | Lyssenko NN et al. | β | 2008 | β |
| Autophagy in Caenorhabditis elegans. | Sigmond T et al. | β | 2008 | β |
| Autophagy is required for necrotic cell death in Caenorhabditis elegans. | Samara C et al. | β | 2008 | β |
| Caenorhabditis elegans mboa-7, a member of the MBOAT family, is required for selective incorporation of polyunsaturated fatty acids into phosphatidylinositol. | Lee HC et al. | β | 2008 | β |
| C. elegans nucleostemin is required for larval growth and germline stem cell division. | Kudron MM et al. | β | 2008 | β |
| cin-4, a gene with homology to topoisomerase II, is required for centromere resolution by cohesin removal from sister kinetochores during mitosis. | Stanvitch G et al. | β | 2008 | β |
| DEPS-1 promotes P-granule assembly and RNA interference in C. elegans germ cells. | Spike CA et al. | β | 2008 | β |
| Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans. | Tullet JM et al. | β | 2008 | β |
| Exploring systemic RNA interference in insects: a genome-wide survey for RNAi genes in Tribolium. | Tomoyasu Y et al. | β | 2008 | β |
| Function of the PHA-4/FOXA transcription factor during C. elegans post-embryonic development. | Chen D et al. | β | 2008 | β |
| Genetic analysis of the Caenorhabditis elegans GLH family of P-granule proteins. | Spike C et al. | β | 2008 | β |
| Genetic impairment of autophagy intensifies expanded polyglutamine toxicity in Caenorhabditis elegans. | Khan LA et al. | β | 2008 | β |
| Highly Ca2+-selective TRPM channels regulate IP3-dependent oscillatory Ca2+ signaling in the C. elegans intestine. | Xing J et al. | β | 2008 | β |
| Inhibition of Henipavirus infection by RNA interference. | Mungall BA et al. | β | 2008 | β |
| Maintenance of mitochondrial DNA by the Caenorhabditis elegans ATR checkpoint protein ATL-1. | Mori C et al. | β | 2008 | β |
| Mesodermal expression of the C. elegans HMX homolog mls-2 requires the PBC homolog CEH-20. | Jiang Y et al. | β | 2008 | β |
| Metabolic pathway profiling of mitochondrial respiratory chain mutants in C. elegans. | Falk MJ et al. | β | 2008 | β |
| Molecular characterization of two homologs of the Caenorhabditis elegans cadmium-responsive gene cdr-1: cdr-4 and cdr-6. | Dong J et al. | β | 2008 | β |
| Muscle cell migrations of C. elegans are mediated by the alpha-integrin INA-1, Eph receptor VAB-1, and a novel peptidase homologue MNP-1. | Tucker M et al. | β | 2008 | β |
| Sex change by gene conversion in a Caenorhabditis elegans fog-2 mutant. | Katju V et al. | β | 2008 | β |
| Single-copy insertion of transgenes in Caenorhabditis elegans. | FrΓΈkjaer-Jensen C et al. | β | 2008 | β |
| SPDL-1 functions as a kinetochore receptor for MDF-1 in Caenorhabditis elegans. | Yamamoto TG et al. | β | 2008 | β |
| The Caenorhabditis elegans AMP-activated protein kinase AAK-2 is phosphorylated by LKB1 and is required for resistance to oxidative stress and for normal motility and foraging behavior. | Lee H et al. | β | 2008 | β |
| The Caenorhabditis elegans ekl (enhancer of ksr-1 lethality) genes include putative components of a germline small RNA pathway. | Rocheleau CE et al. | β | 2008 | β |
| The Caenorhabditis elegans NR4A nuclear receptor is required for spermatheca morphogenesis. | Gissendanner CR et al. | β | 2008 | β |
| The CRL4Cdt2 ubiquitin ligase targets the degradation of p21Cip1 to control replication licensing. | Kim Y et al. | β | 2008 | β |
| The FLYWCH transcription factors FLH-1, FLH-2, and FLH-3 repress embryonic expression of microRNA genes in C. elegans. | Ow MC et al. | β | 2008 | β |
| Use of RNAi in C. elegans. | Ohkumo T et al. | β | 2008 | β |
| Activation of SKN-1 by novel kinases in Caenorhabditis elegans. | Kell A et al. | β | 2007 | β |
| A Measurable increase in oxidative damage due to reduction in superoxide detoxification fails to shorten the life span of long-lived mitochondrial mutants of Caenorhabditis elegans. | Yang W et al. | β | 2007 | β |
| A modular network model of aging. | Xue H et al. | β | 2007 | β |
| An explicit test of the phospholipid saturation hypothesis of acquired cold tolerance in Caenorhabditis elegans. | Murray P et al. | β | 2007 | β |
| A ONECUT homeodomain protein communicates X chromosome dose to specify Caenorhabditis elegans sexual fate by repressing a sex switch gene. | Gladden JM et al. | β | 2007 | β |
| Axon guidance genes identified in a large-scale RNAi screen using the RNAi-hypersensitive Caenorhabditis elegans strain nre-1(hd20) lin-15b(hd126). | Schmitz C et al. | β | 2007 | β |
| Axons break in animals lacking beta-spectrin. | Hammarlund M et al. | β | 2007 | β |
| Cortical granule exocytosis in C. elegans is regulated by cell cycle components including separase. | Bembenek JN et al. | β | 2007 | β |
| CRAC channel activity in C. elegans is mediated by Orai1 and STIM1 homologues and is essential for ovulation and fertility. | Lorin-Nebel C et al. | β | 2007 | β |
| Dynein modifiers in C. elegans: light chains suppress conditional heavy chain mutants. | O'Rourke SM et al. | β | 2007 | β |
| Epigenetic regulation of histone H3 serine 10 phosphorylation status by HCF-1 proteins in C. elegans and mammalian cells. | Lee S et al. | β | 2007 | β |
| Evolutionarily conserved WNK and Ste20 kinases are essential for acute volume recovery and survival after hypertonic shrinkage in Caenorhabditis elegans. | Choe KP et al. | β | 2007 | β |
| Evolutionary conservation of regulated longevity assurance mechanisms. | McElwee JJ et al. | β | 2007 | β |
| Huntingtin-interacting protein 1 influences worm and mouse presynaptic function and protects Caenorhabditis elegans neurons against mutant polyglutamine toxicity. | Parker JA et al. | β | 2007 | β |
| Inhibition of mRNA translation extends lifespan in Caenorhabditis elegans. | Pan KZ et al. | β | 2007 | β |
| Longevity determined by developmental arrest genes in Caenorhabditis elegans. | Chen D et al. | β | 2007 | β |
| No influence of Indy on lifespan in Drosophila after correction for genetic and cytoplasmic background effects. | Toivonen JM et al. | β | 2007 | β |
| PHA-4/FoxA cooperates with TAM-1/TRIM to regulate cell fate restriction in the C. elegans foregut. | Kiefer JC et al. | β | 2007 | β |
| Phosphoethanolamine N-methyltransferase (PMT-1) catalyses the first reaction of a new pathway for phosphocholine biosynthesis in Caenorhabditis elegans. | Brendza KM et al. | β | 2007 | β |
| Recent progress in the development of RNA interference for plant parasitic nematodes. | Lilley CJ et al. | β | 2007 | β |
| Regulation of developmental rate and germ cell proliferation in Caenorhabditis elegans by the p53 gene network. | Derry WB et al. | β | 2007 | β |
| Relationship between mitochondrial electron transport chain dysfunction, development, and life extension in Caenorhabditis elegans. | Rea SL et al. | β | 2007 | β |
| Revisiting the Krogh Principle in the post-genome era: Caenorhabditis elegans as a model system for integrative physiology research. | Strange K | β | 2007 | β |
| Similar requirements for CDC-42 and the PAR-3/PAR-6/PKC-3 complex in diverse cell types. | Welchman DP et al. | β | 2007 | β |
| The Caenorhabditis elegans replication licensing factor CDT-1 is targeted for degradation by the CUL-4/DDB-1 complex. | Kim Y et al. | β | 2007 | β |
| The C. elegans Twist target gene, arg-1, is regulated by distinct E box promoter elements. | Zhao J et al. | β | 2007 | β |
| The UNC-45 chaperone mediates sarcomere assembly through myosin degradation in Caenorhabditis elegans. | Landsverk ML et al. | β | 2007 | β |
| A biochemist's guide to Caenorhabditis elegans. | Corsi AK | β | 2006 | β |
| A recombineering pipeline for functional genomics applied to Caenorhabditis elegans. | Sarov M et al. | β | 2006 | β |
| Caenorhabditis elegans ivermectin receptors regulate locomotor behaviour and are functional orthologues of Haemonchus contortus receptors. | Cook A et al. | β | 2006 | β |
| Cell fate-specific regulation of EGF receptor trafficking during Caenorhabditis elegans vulval development. | Stetak A et al. | β | 2006 | β |
| CeRh1 (rhr-1) is a dominant Rhesus gene essential for embryonic development and hypodermal function in Caenorhabditis elegans. | Ji Q et al. | β | 2006 | β |
| Deficiency of the Caenorhabditis elegans DNA polymerase eta homologue increases sensitivity to UV radiation during germ-line development. | Ohkumo T et al. | β | 2006 | β |
| Developmental modulation of nonhomologous end joining in Caenorhabditis elegans. | Clejan I et al. | β | 2006 | β |
| Effects of sex and insulin/insulin-like growth factor-1 signaling on performance in an associative learning paradigm in Caenorhabditis elegans. | Vellai T et al. | β | 2006 | β |
| Finding function in novel targets: C. elegans as a model organism. | Kaletta T et al. | β | 2006 | β |
| Function of a STIM1 homologue in C. elegans: evidence that store-operated Ca2+ entry is not essential for oscillatory Ca2+ signaling and ER Ca2+ homeostasis. | Yan X et al. | β | 2006 | β |
| Genetic interactions among cortical malformation genes that influence susceptibility to convulsions in C. elegans. | Locke CJ et al. | β | 2006 | β |
| Genetic regulation of unsaturated fatty acid composition in C. elegans. | Brock TJ et al. | β | 2006 | β |
| Genomic clusters, putative pathogen recognition molecules, and antimicrobial genes are induced by infection of C. elegans with M. nematophilum. | O'Rourke D et al. | β | 2006 | β |
| Identification of novel chondroitin proteoglycans in Caenorhabditis elegans: embryonic cell division depends on CPG-1 and CPG-2. | Olson SK et al. | β | 2006 | β |
| Lysosomal biogenesis and function is critical for necrotic cell death in Caenorhabditis elegans. | Artal-Sanz M et al. | β | 2006 | β |
| New developmental insights from high-throughput biological analysis in Caenorhabditis elegans. | LabbΓ© JC et al. | β | 2006 | β |
| Proteasomal ubiquitin receptor RPN-10 controls sex determination in Caenorhabditis elegans. | Shimada M et al. | β | 2006 | β |
| RNA interference: natural, experimental, and clinical roles in cancer biology. | Mroz EA et al. | β | 2006 | β |
| RNA interference of the salivary gland nitrophorin 2 in the triatomine bug Rhodnius prolixus (Hemiptera: Reduviidae) by dsRNA ingestion or injection. | Araujo RN et al. | β | 2006 | β |
| RNA: Networks & Imaging. | Kenzelmann M et al. | β | 2006 | β |
| The adaptor protein soc-1/Gab1 modifies growth factor receptor output in Caenorhabditis elegans. | Hopper NA | β | 2006 | β |
| The autophagy-related kinase UNC-51 and its binding partner UNC-14 regulate the subcellular localization of the Netrin receptor UNC-5 in Caenorhabditis elegans. | Ogura K et al. | β | 2006 | β |
| The Caenorhabditis elegans rhy-1 gene inhibits HIF-1 hypoxia-inducible factor activity in a negative feedback loop that does not include vhl-1. | Shen C et al. | β | 2006 | β |
| TILLING is an effective reverse genetics technique for Caenorhabditis elegans. | Gilchrist EJ et al. | β | 2006 | β |
| Two membrane-associated tyrosine phosphatase homologs potentiate C. elegans AKT-1/PKB signaling. | Hu PJ et al. | β | 2006 | β |
| VHA-8, the E subunit of V-ATPase, is essential for pH homeostasis and larval development in C. elegans. | Ji YJ et al. | β | 2006 | β |
| ACT-5 is an essential Caenorhabditis elegans actin required for intestinal microvilli formation. | MacQueen AJ et al. | β | 2005 | β |
| ATP-2 interacts with the PLAT domain of LOV-1 and is involved in Caenorhabditis elegans polycystin signaling. | Hu J et al. | β | 2005 | β |
| Characterisation of the two most abundant genes in the Haemonchus contortus expressed sequence tag dataset. | Geldhof P et al. | β | 2005 | β |
| Characterization of gana-1, a Caenorhabditis elegans gene encoding a single ortholog of vertebrate alpha-galactosidase and alpha-N-acetylgalactosaminidase. | HujovΓ‘ J et al. | β | 2005 | β |
| Chromatin regulation and sumoylation in the inhibition of Ras-induced vulval development in Caenorhabditis elegans. | Poulin G et al. | β | 2005 | β |
| Cyclin D regulation of a sexually dimorphic asymmetric cell division. | Tilmann C et al. | β | 2005 | β |
| Dose-dependent inhibition of gynecophoral canal protein gene expression in vitro in the schistosome (Schistosoma japonicum) by RNA interference. | Cheng GF et al. | β | 2005 | β |
| Functional analysis of cytoplasmic dynein heavy chain in Caenorhabditis elegans with fast-acting temperature-sensitive mutations. | Schmidt DJ et al. | β | 2005 | β |
| Genetic interactions due to constitutive and inducible gene regulation mediated by the unfolded protein response in C. elegans. | Shen X et al. | β | 2005 | β |
| Heparan 2-O-sulfotransferase, hst-2, is essential for normal cell migration in Caenorhabditis elegans. | Kinnunen T et al. | β | 2005 | β |
| Heritable and inducible gene knockdown in C. elegans using Wormgate and the ORFeome. | Johnson NM et al. | β | 2005 | β |
| Mutations that rescue the paralysis of Caenorhabditis elegans ric-8 (synembryn) mutants activate the G alpha(s) pathway and define a third major branch of the synaptic signaling network. | Schade MA et al. | β | 2005 | β |
| Neuromuscular function in plant parasitic nematodes: a target for novel control strategies? | Kimber MJ et al. | β | 2005 | β |
| New genes tied to endocrine, metabolic, and dietary regulation of lifespan from a Caenorhabditis elegans genomic RNAi screen. | Hansen M et al. | β | 2005 | β |
| Oscillatory Ca2+ signaling in the isolated Caenorhabditis elegans intestine: role of the inositol-1,4,5-trisphosphate receptor and phospholipases C beta and gamma. | Espelt MV et al. | β | 2005 | β |
| SMA-1 spectrin has essential roles in epithelial cell sheet morphogenesis in C. elegans. | Praitis V et al. | β | 2005 | β |
| The C. elegans homolog of the mammalian tumor suppressor Dep-1/Scc1 inhibits EGFR signaling to regulate binary cell fate decisions. | Berset TA et al. | β | 2005 | β |
| The T-box transcription factor SEA-1 is an autosomal element of the X:A signal that determines C. elegans sex. | Powell JR et al. | β | 2005 | β |
| C. elegans LIN-18 is a Ryk ortholog and functions in parallel to LIN-17/Frizzled in Wnt signaling. | Inoue T et al. | β | 2004 | β |
| Centrosome maturation and duplication in C. elegans require the coiled-coil protein SPD-2. | Kemp CA et al. | β | 2004 | β |
| EGF signal propagation during C. elegans vulval development mediated by ROM-1 rhomboid. | Dutt A et al. | β | 2004 | β |
| Genetic models of mechanotransduction: the nematode Caenorhabditis elegans. | Syntichaki P et al. | β | 2004 | β |
| Inositol 1,4,5-trisphosphate signaling regulates rhythmic contractile activity of myoepithelial sheath cells in Caenorhabditis elegans. | Yin X et al. | β | 2004 | β |
| Loss of KLP-19 polar ejection force causes misorientation and missegregation of holocentric chromosomes. | Powers J et al. | β | 2004 | β |
| Lumen morphogenesis in C. elegans requires the membrane-cytoskeleton linker erm-1. | GΓΆbel V et al. | β | 2004 | β |
| Metalloproteases with EGF, CUB, and thrombospondin-1 domains function in molting of Caenorhabditis elegans. | Suzuki M et al. | β | 2004 | β |
| Monomethyl branched-chain fatty acids play an essential role in Caenorhabditis elegans development. | Kniazeva M et al. | β | 2004 | β |
| RNAi: ancient mechanism with a promising future. | Geley S et al. | β | 2004 | β |
| The 5'-3' exoribonuclease xrn-1 is essential for ventral epithelial enclosure during C. elegans embryogenesis. | Newbury S et al. | β | 2004 | β |
| The Caenorhabditis elegans cathepsin Z-like cysteine protease, Ce-CPZ-1, has a multifunctional role during the worms' development. | Hashmi S et al. | β | 2004 | β |
| The Caenorhabditis elegans nuclear receptor gene nhr-25 regulates epidermal cell development. | Chen Z et al. | β | 2004 | β |
| The Caenorhabditis elegans ortholog of TRAP240, CeTRAP240/let-19, selectively modulates gene expression and is essential for embryogenesis. | Wang JC et al. | β | 2004 | β |
| The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span. | Jia K et al. | β | 2004 | β |
| An Eph receptor sperm-sensing control mechanism for oocyte meiotic maturation in Caenorhabditis elegans. | Miller MA et al. | β | 2003 | β |
| Chondroitin proteoglycans are involved in cell division of Caenorhabditis elegans. | Mizuguchi S et al. | β | 2003 | β |
| Differential activation of the DNA replication checkpoint contributes to asynchrony of cell division in C. elegans embryos. | Brauchle M et al. | β | 2003 | β |
| Enzymes involved in the biogenesis of the nematode cuticle. | Page AP et al. | β | 2003 | β |
| From genes to integrative physiology: ion channel and transporter biology in Caenorhabditis elegans. | Strange K | β | 2003 | β |
| Genome-wide insertional mutagenesis of Arabidopsis thaliana. | Alonso JM et al. | β | 2003 | β |
| Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes. | Ashrafi K et al. | β | 2003 | β |
| Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals novel gene functions. | Simmer F et al. | β | 2003 | β |
| Identification of genes that protect the C. elegans genome against mutations by genome-wide RNAi. | Pothof J et al. | β | 2003 | β |
| Involvement of fatty acid pathways and cortical interaction of the pronuclear complex in Caenorhabditis elegans embryonic polarity. | Rappleye CA et al. | β | 2003 | β |
| KLP-18, a Klp2 kinesin, is required for assembly of acentrosomal meiotic spindles in Caenorhabditis elegans. | Segbert C et al. | β | 2003 | β |
| MEI-1/katanin is required for translocation of the meiosis I spindle to the oocyte cortex in C elegans. | Yang HY et al. | β | 2003 | β |
| Nuclear pore protein gp210 is essential for viability in HeLa cells and Caenorhabditis elegans. | Cohen M et al. | β | 2003 | β |
| RNA interference with small hairpin RNAs transcribed from a human U6 promoter-driven DNA vector. | Kwak YD et al. | β | 2003 | β |
| Suppression of CED-3-independent apoptosis by mitochondrial betaNAC in Caenorhabditis elegans. | Bloss TA et al. | β | 2003 | β |
| The Caenorhabditis elegans orthologue of mammalian puromycin-sensitive aminopeptidase has roles in embryogenesis and reproduction. | Brooks DR et al. | β | 2003 | β |
| The Caenorhabditis elegans p120 catenin homologue, JAC-1, modulates cadherin-catenin function during epidermal morphogenesis. | Pettitt J et al. | β | 2003 | β |
| The mitochondrial prohibitin complex is essential for embryonic viability and germline function in Caenorhabditis elegans. | Artal-Sanz M et al. | β | 2003 | β |
| The specifics of small interfering RNA specificity. | Dillin A | β | 2003 | β |
| Tissue-specific activities of C. elegans DAF-16 in the regulation of lifespan. | Libina N et al. | β | 2003 | β |
| Use of RNA interference to investigate gene function in the human filarial nematode parasite Brugia malayi. | Aboobaker AA et al. | β | 2003 | β |
| Whole-genome analysis of 60 G protein-coupled receptors in Caenorhabditis elegans by gene knockout with RNAi. | Keating CD et al. | β | 2003 | β |
| Disruption of dog-1 in Caenorhabditis elegans triggers deletions upstream of guanine-rich DNA. | Cheung I et al. | β | 2002 | β |
| Functional and phylogenetic analysis of the ubiquitylation system in Caenorhabditis elegans: ubiquitin-conjugating enzymes, ubiquitin-activating enzymes, and ubiquitin-like proteins. | Jones D et al. | β | 2002 | β |
| Ingestion of double-stranded RNA by preparasitic juvenile cyst nematodes leads to RNA interference. | Urwin PE et al. | β | 2002 | β |
| Interaction of intracellular beta amyloid peptide with chaperone proteins. | Fonte V et al. | β | 2002 | β |
| Loss of spr-5 bypasses the requirement for the C.elegans presenilin sel-12 by derepressing hop-1. | Eimer S et al. | β | 2002 | β |
| Loss of the putative RNA-directed RNA polymerase RRF-3 makes C. elegans hypersensitive to RNAi. | Simmer F et al. | β | 2002 | β |
| Reverse genetic analysis of the Caenorhabditis elegans 26S proteasome subunits by RNA interference. | Takahashi M et al. | β | 2002 | β |
| RNAi in Dictyostelium: the role of RNA-directed RNA polymerases and double-stranded RNase. | Martens H et al. | β | 2002 | β |
| RNA interference by feeding in Paramecium. | Galvani A et al. | β | 2002 | β |
| Suppression of secreted acetylcholinesterase expression in Nippostrongylus brasiliensis by RNA interference. | Hussein AS et al. | β | 2002 | β |
| The anaphase-promoting complex and separin are required for embryonic anterior-posterior axis formation. | Rappleye CA et al. | β | 2002 | β |
| The Axin-like protein PRY-1 is a negative regulator of a canonical Wnt pathway in C. elegans. | Korswagen HC et al. | β | 2002 | β |
| The genetics of RNA silencing. | Tijsterman M et al. | β | 2002 | β |
| An isoform of eIF4E is a component of germ granules and is required for spermatogenesis in C. elegans. | Amiri A et al. | β | 2001 | β |
| DLG-1 is a MAGUK similar to SAP97 and is required for adherens junction formation. | Firestein BL et al. | β | 2001 | β |
| High-throughput reverse genetics: RNAi screens in Caenorhabditis elegans. | Bargmann CI | β | 2001 | β |
| Http://C. elegans: mining the functional genomic landscape. | Kim SK | β | 2001 | β |
| RNAi is antagonized by A-->I hyper-editing. | Scadden AD et al. | β | 2001 | β |
| Roles for 147 embryonic lethal genes on C.elegans chromosome I identified by RNA interference and video microscopy. | Zipperlen P et al. | β | 2001 | β |