The adolescent origins of substance use disorders.
paper
Cited
Public
Unavailable
- Authors
- McGue, Matt; Iacono, William G
- Year
- 2008
- Journal
- International journal of methods in psychiatric research
- PMID
- 18543360
- DOI
- 10.1002/mpr.242
- PMCID
- PMC2581497
Although early use of alcohol during adolescence has been consistently associated with increased risk of alcoholism in adulthood, the specific mechanisms that underlie this association remain unclear. We describe a program of epidemiological twin-family research that shows that early use of alcohol is best conceptualized as an indicator of a more general propensity to engage in adolescent problem behavior. Adolescent problem behavior, in turn, is a risk factor for a broad range of adult externalizing disorders, of which alcoholism is but one manifestation. These findings are shown to be consistent with a dual-process model whereby early adolescent problem behavior is associated with increased risk of adult psychopathology because both are indicators of a common inherited liability and because early adolescent problem behavior increases the likelihood an adolescent is exposed to high-risk environments. We conclude with a discussion of the importance of cross-cultural research, which may be especially informative for identifying the consequences of early adolescent drinking.
No figures extracted from this document.
No chunks — full text not yet ingested.
No entities extracted from this document yet.
No uploaded files.
Not in any collection.
No citations found.
In this knowledge base
External
| Title | Authors | Journal | Year | Link |
|---|---|---|---|---|
| International trends in male youth suicide and suicidal behaviour. | Rice T et al. | — | 2024 | → |
| Factors associated with crack-cocaine early initiation: a Brazilian multicenter study. | Perrenoud LO et al. | — | 2021 | → |
| Consequences of alcohol use, and its association with psychological distress, sensitivity to emotional contagion and age of onset of alcohol use, in Uruguayan youth with or without college degree. | Ruiz P et al. | — | 2020 | → |
| ELSA cohort 2014: association of age of first drink and progression from first drink to drunkenness on alcohol outcomes in Argentinean college freshmen. | Vera BDV et al. | — | 2020 | → |
| Longitudinal Relations among Adolescent Risk Behavior, Family Cohesion, Violence Exposure, and Mental Health in a National Sample. | Goodrum NM et al. | — | 2020 | → |
| Is Apostasy Heritable? A Behavior Genetics Study. | Freeman JA | — | 2019 | → |
| Medications for Maintenance Treatment of Opioid Use Disorder in Adolescents: A Narrative Review and Assessment of Clinical Benefits and Potential Risks, Offering a Public Health Perspective-A Commentary on Camenga et al. | Gonzales-Castaneda R et al. | — | 2019 | → |
| Police Stops Among At-Risk Youth: Repercussions for Mental Health. | Jackson DB et al. | — | 2019 | → |
| Childhood Risk Factors for Heavy Episodic Alcohol Use and Alcohol Problems in Late Adolescence: A Marginal Structural Model Analysis. | Kendler KS et al. | — | 2018 | → |
| A developmental model for alcohol use disorders in Swedish men. | Kendler KS et al. | — | 2016 | → |
| Altered developmental trajectories for impulsivity and sensation seeking among adolescent substance users. | Charles NE et al. | — | 2016 | → |
| A prospective longitudinal model predicting early adult alcohol problems: evidence for a robust externalizing pathway. | Edwards AC et al. | — | 2016 | → |
| Declining Rates of Adolescent Marijuana Use Disorders During the Past Decade May Be Due to Declining Conduct Problems. | Hopfer C | — | 2016 | → |
| Effects of parental monitoring on alcohol use in the US and Sweden: A brief report. | Carroll HA et al. | — | 2016 | → |
| Evidence for Association Between Low Frequency Variants in CHRNA6/CHRNB3 and Antisocial Drug Dependence. | Kamens HM et al. | — | 2016 | → |
| Parental Substance Abuse As an Early Traumatic Event. Preliminary Findings on Neuropsychological and Personality Functioning in Young Drug Addicts Exposed to Drugs Early. | Parolin M et al. | — | 2016 | → |
| Adolescent deviant peer clustering as an amplifying mechanism underlying the progression from early substance use to late adolescent dependence. | Van Ryzin MJ et al. | — | 2014 | → |
| Early adolescent patterns of alcohol, cigarettes, and marijuana polysubstance use and young adult substance use outcomes in a nationally representative sample. | Moss HB et al. | — | 2014 | → |
| A cluster randomized trial on the effects of a parent and student intervention on alcohol use in adolescents four years after baseline; no evidence of catching-up behavior. | Koning IM et al. | — | 2013 | → |
| Distinct loci in the CHRNA5/CHRNA3/CHRNB4 gene cluster are associated with onset of regular smoking. | Stephens SH et al. | — | 2013 | → |
| The burden of alcohol use: focus on children and preadolescents. | Donovan JE | — | 2013 | → |
| Examining explanatory mechanisms of the effects of early alcohol use on young adult alcohol dependence. | Guttmannova K et al. | — | 2012 | → |
| Externalizing behaviors are associated with SNPs in the CHRNA5/CHRNA3/CHRNB4 gene cluster. | Stephens SH et al. | — | 2012 | → |
| Illuminating the relationship between bullying and substance use among middle and high school youth. | Radliff KM et al. | — | 2012 | → |
| Protective predictors of alcohol use trajectories among Canadian Aboriginal youth. | Rawana JS et al. | — | 2012 | → |
| The importance of family factors to protect against substance use related problems among Mexican heritage and White youth. | Kopak AM et al. | — | 2012 | → |
| The relevance of age at first alcohol and nicotine use for initiation of cannabis use and progression to cannabis use disorders. | Behrendt S et al. | — | 2012 | → |
| Chronic alcohol neuroadaptation and stress contribute to susceptibility for alcohol craving and relapse. | Breese GR et al. | — | 2011 | → |
| The role of mental disorders in the risk and speed of transition to alcohol use disorders among community youth. | Behrendt S et al. | — | 2011 | → |
| Toward a comprehensive developmental model for alcohol use disorders in men. | Kendler KS et al. | — | 2011 | → |
| Consilient research approaches in studying gene x environment interactions in alcohol research. | Sher KJ et al. | — | 2010 | → |
| For distinguished contributions to psychophysiology: William G. Iacono. | Miller GA | — | 2010 | → |
| Genetic and environmental risk factors for adolescent-onset substance use disorders. | Meyers JL et al. | — | 2010 | → |
| Mechanisms underlying the lifetime co-occurrence of tobacco and cannabis use in adolescent and young adult twins. | Agrawal A et al. | — | 2010 | → |
| The end of behavioral genetics? 2008. | McGue M | — | 2010 | → |
| A typology of cannabis-related problems among individuals with repeated illegal drug use in the first three decades of life: Evidence for heterogeneity and different treatment needs. | Wittchen HU et al. | — | 2009 | → |
| Developmental epidemiology of drug use and abuse in adolescence and young adulthood: Evidence of generalized risk. | Palmer RH et al. | — | 2009 | → |
| The enrichment study of the Minnesota twin family study: increasing the yield of twin families at high risk for externalizing psychopathology. | Keyes MA et al. | — | 2009 | → |
| Alcohol and drug treatment systems in public health perspective: mediators and moderators of population effects. | Babor TF et al. | — | 2008 | → |
| Behavioral disinhibition and the development of early-onset addiction: common and specific influences. | Iacono WG et al. | — | 2008 | → |
| The End of Behavioral Genetics? | McGue M | — | 2008 | → |
| Understanding addiction--mediators and moderators of behaviour change processes: an introduction. | Bühringer G et al. | — | 2008 | → |