Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources.
- Authors
- Huang, Da Wei; Sherman, Brad T; Lempicki, Richard A
- Year
- 2009
- Journal
- Nature protocols
- PMID
- 19131956
- DOI
- 10.1038/nprot.2008.211
DAVID bioinformatics resources consists of an integrated biological knowledgebase and analytic tools aimed at systematically extracting biological meaning from large gene/protein lists. This protocol explains how to use DAVID, a high-throughput and integrated data-mining environment, to analyze gene lists derived from high-throughput genomic experiments. The procedure first requires uploading a gene list containing any number of common gene identifiers followed by analysis using one or more text and pathway-mining tools such as gene functional classification, functional annotation chart or clustering and functional annotation table. By following this protocol, investigators are able to gain an in-depth understanding of the biological themes in lists of genes that are enriched in genome-scale studies.
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| Chemical Composition and Biological Activities of <i>Pelargonium</i> sp.: A Review with In Silico Insights into Potential Anti-Inflammatory Mechanism. | Celi D et al. | β | 2025 | β |
| Chemoselective Characterization of New Extracellular Matrix Deposition in Bioengineered Tumor Tissues. | Ling Z et al. | β | 2025 | β |
| Chondrogenic Potential of Cryopreserved Aortic Allografts: Guiding Perichondrial Regeneration in Tracheal Repair. | Hung WT et al. | β | 2025 | β |
| Chromatin looping-based CRISPR screen identifies TLK2 as chromatin loop formation regulator in cancer stemness plasticity. | Wang Z et al. | β | 2025 | β |
| Chromatin profiling data indicate regulatory mechanisms for differentiation during development in the acoel Hofstenia miamia. | Bump P et al. | β | 2025 | β |
| Chromatin structural gene expression stratifies cardiac cell populations in health and disease. | Geng X et al. | β | 2025 | β |
| Chromosome level assembly and annotation of Cuscuta campestris Yunck. ("field dodder"), a model parasitic plant. | Cerda-Herrera JD et al. | β | 2025 | β |
| Chromosome-level genome assembly of the doctor fish (Garra rufa). | Kon T et al. | β | 2025 | β |
| Chromosome structural variation analysis reveals lung cancer-associated gene regulatory networks in rheumatoid arthritis patients. | Li H et al. | β | 2025 | β |
| Circadian clocks and periodic anticipated fasting prevent fasting-associated hepatic steatosis in calorie restriction. | Ebeigbe OP et al. | β | 2025 | β |
| Citri Sarcodactylis Fructus Alleviates LPS-Induced Acute Lung Injury by Inhibiting Inflammation and Inflammasome Activation. | Luo Z et al. | β | 2025 | β |
| Cohesive data analysis for the identification of prognostic hub genes and significant pathways associated with HER2β+βand TN breast cancer types. | Zakir M et al. | β | 2025 | β |
| Colorectal cancer cell line-derived organoid model with stem cell properties captures the regrowing state of residual cancer cells after neoadjuvant chemotherapy. | Nakano K et al. | β | 2025 | β |
| Combined cellular and proteomics approach suggests differential processing of a native and a foreign vibrio in the sponge <i>Halicondria panicea</i>. | Marulanda-Gomez AM et al. | β | 2025 | β |
| Common and distinct circulating microRNAs in four neurovascular disorders. | KoskimΓ€ki J et al. | β | 2025 | β |
| Comparative genomic insights into adaptation, selection signatures, and population dynamics in indigenous Indian sheep and foreign breeds. | Muthusamy M et al. | β | 2025 | β |
| Comparative meta-analysis of barely transcriptome: Pathogen type determines host preference. | Soltani Z et al. | β | 2025 | β |
| Comparative proteomic analysis of receptive and non-receptive endometria-derived uterine fluid suggests a panel for endometrial receptivity assessment. | Saraee F et al. | β | 2025 | β |
| Comparative transcriptome analysis of PBMCs in cats diagnosed with and recovered from FIPV. | Lee JY et al. | β | 2025 | β |
| Comparative transcriptome analysis reveals genes associated with variation in liver copper concentration in Polish Merino sheep. | Adeniyi OO et al. | β | 2025 | β |
| Comparative transcriptomic analysis reveals breed-specific developmental characters of skin and feather follicles between Anser Cygnoides and Anser Anser. | Mabrouk I et al. | β | 2025 | β |
| Comparative transcriptomic and meat quality responses to electrical and controlled atmosphere stunning in broiler chickens. | Ham CH et al. | β | 2025 | β |
| Comparisons of miRNA profiles of exosomes derived from human iPSCs, ADSCs, and BMSCs and effects on chondrocyte function. | Chang LH et al. | β | 2025 | β |
| Comprehensive mapping of Arabidopsis alternative splicing landscape reveals key insights into plant development and immunity. | Barff T et al. | β | 2025 | β |
| Comprehensive Mendelian randomization and colocalization analysis of plasma proteomics to identify new therapeutic targets for bladder cancer. | Zuo J et al. | β | 2025 | β |
| Comprehensive Physiological and Transcriptomic Profiling of Triploid Pacific Oysters (<i>Crassostrea gigas</i>) Under Ammonia Exposure. | Liu X et al. | β | 2025 | β |
| Computational strategies in systems-level stress response data analysis. | Jung F et al. | β | 2025 | β |
| Conserved functional features of natural killer cell subsets in chicken, human, and murine immune systems. | Woo SJ et al. | β | 2025 | β |
| Constitutive expression of cardiomyocyte Klf9 precipitates metabolic dysfunction and spontaneous cardiomyopathy. | Thakkar C et al. | β | 2025 | β |
| Construction and Identification of Inflammation-Related TF-mRNA-miRNA Coexpression Network and Immune Infiltration in Parkinson's Disease. | Shen Z et al. | β | 2025 | β |
| Construction of a Genome-Wide Copy Number Variation Map and Association Analysis of Black Spot in Jujube. | Luo Y et al. | β | 2025 | β |
| Construction of Coexpression Networks Affecting Litter Size in Goats Based on Transcriptome Analysis. | Ren Y et al. | β | 2025 | β |
| Coordinated histone methylation loss and MYC activation promote translational capacity under amino acid restriction. | Cheng C et al. | β | 2025 | β |
| Correlation of Galectin Family Expression with Glioblastoma Progression and Survival. | Curpen P et al. | β | 2025 | β |
| Cortisol-Induced Chromatin Remodeling and Gene Expression in Skeletal Muscle of Rainbow Trout: Integrative ATAC-Seq and RNA-Seq Analysis. | Zuloaga R et al. | β | 2025 | β |
| Cross-disease transcriptomic meta-analysis and network pharmacology reveal key therapeutic targets in rheumatoid arthritis, systemic lupus erythematosus and multiple sclerosis. | Lakshmi K et al. | β | 2025 | β |
| Cross-Species Insights into <i>In Vitro</i> Maturation Defects of the Oocyte and Identification of Crucial Regulators for Sheep Oocyte Maturation. | Cui J et al. | β | 2025 | β |
| Cross-Species Transcriptomic and Metabolomic Analysis Reveals Conserved and Divergent Fatty Acid Metabolic Regulatory Strategies During Mammalian Oocyte Maturation. | Elashry M et al. | β | 2025 | β |
| Crotonylation of IDH1 alleviates MASLD progression by enhancing the TCA cycle. | Liu S et al. | β | 2025 | β |
| Cutaneous T-Cell Lymphoma: Yin-Yang Effects of Transcription Factors HLF and NFIL3 in Regulation of Malignant T-Cell Markers in the Context of HDAC Inhibitor Romidepsin Treatment. | Kossenkov AV et al. | β | 2025 | β |
| Cytokine supplementation influences bovine embryo transcriptome during the preimplantation period. | McDonald KS et al. | β | 2025 | β |
| Data-Independent Acquisition (DIA)-Based Label-Free Redox Proteomics (DIALRP) Identifies Prominent Cysteine Oxidations in Translation Machinery in Prostate Cancer Cells Under Oxidative Stress. | Kobayashi D et al. | β | 2025 | β |
| Deciphering molecular overlaps between COPD and NSCLC subtypes (LUAD and LUSC): An integrative bioinformatics study. | AkΓ§ay S | β | 2025 | β |
| Deciphering the Regulatory Potential of Antioxidant and Electron-Shuttling Bioactive Compounds in Oolong Tea. | Ferrer RA et al. | β | 2025 | β |
| Decoding the DNA of Anatolian water buffalo by genome-wide discoveries for body size and ultrasound carcass traits. | Γinkaya S et al. | β | 2025 | β |
| Deepening the Modulatory Activity of Bioactive Compounds Against AFB1- and OTA-Induced Neuronal Toxicity Through a Proteomic Approach. | Cimbalo A et al. | β | 2025 | β |
| Deep learning algorithms reveal genomic markers for anxiety disorder in a large cohort of children with down syndrome. | Liu Y et al. | β | 2025 | β |
| Defensive fungal symbiosis on insect hindlegs. | Nishino T et al. | β | 2025 | β |
| Deletion of PTP1B in cardiomyocytes alters cardiac metabolic signaling to protect against cardiomyopathy induced by a high-fat diet. | Sun Y et al. | β | 2025 | β |
| Delineating molecular mechanisms on the acquisition of <i>in vitro-</i>adapted colistin-resistant <i>Klebsiella pneumoniae</i> by transcriptomic analysis. | Kyung SM et al. | β | 2025 | β |
| Derivation of embryonic stem cells from cloned blastocysts using improved somatic cell nuclear transfer in common marmosets. | Matoba S et al. | β | 2025 | β |
| Detection of <i>XPO1</i><sup>E571K</sup> Gene Mutation from Cell-Free DNA in Blood Circulation of Lymphoma Patients by FAST-COLD PCR. | Duangmano S et al. | β | 2025 | β |
| Detection of the Candidate Genes of Economically Important Traits in Dorper Sheep Through Whole-Genome Resequencing. | Wang Z et al. | β | 2025 | β |
| Developing a disease-specific accessible transcriptional signature as a biomarker for ataxia with oculomotor apraxia type 2. | Ngo KJ et al. | β | 2025 | β |
| Developing a novel medulloblastoma diagnostic with miRNA biomarkers and machine learning. | Wang C et al. | β | 2025 | β |
| Development and preliminary mechanistic analysis of compound effervescent hepatoprotective granules. | Liu X et al. | β | 2025 | β |
| Development of a 5K Liquid-Phase Genome-Wide Breeding Chip for Xinglong Buffalo. | Jiao Y et al. | β | 2025 | β |
| Development of a High-Throughput Screening Platform and a Pathogenesis Model for <i>Leishmania</i> Infection Based on Mouse Hepatic Organoids. | GonzΓ‘lez-Montero MC et al. | β | 2025 | β |
| DGEAR: a web-based application for differential gene expression analysis and downstream functional insights. | Bardhan K et al. | β | 2025 | β |
| DHDK, a Plant-Derived Natural Small Molecule, Protects Against Doxorubicin-Induced Cardiotoxicity via the PPARG-CPT1B-FAO Axis. | Hong J et al. | β | 2025 | β |
| DHODH Blockade Induces Ferroptosis in Neuroblastoma by Modulating the Mevalonate Pathway. | Shir JC et al. | β | 2025 | β |
| Differences in amino acid and fatty acid metabolism contribute to variability in dairy cattle feed efficiency. | Daddam JR et al. | β | 2025 | β |
| Differential Effects of Liver Regeneration on Aging-Related Changes in Gene Expression and Metabolic Function. | Murayama R et al. | β | 2025 | β |
| Differential expression and hypermethylation of apoptotic genes in circulating nucleic acids are associated with clinical phenotypes of prostate cancer and benign prostatic hyperplasia in Nigerians. | Popoola OA et al. | β | 2025 | β |
| Differential Expression of Erythrocyte Proteins in Patients with Alcohol Use Disorder. | BoΕgelmez IΔ° et al. | β | 2025 | β |
| Differential expression of extracellular vesicle microRNA and granulosa cell mRNA in polycystic ovary syndrome with insulin resistance. | Ju W et al. | β | 2025 | β |
| Differentially regulated saliva proteome and metabolome: a way forward for risk-assessment of oral cancer among tobacco abusers. | Oyeyemi BF et al. | β | 2025 | β |
| Differential neuroprotective mechanisms of rosemary and carnosic acid in cerebral ischemia-reperfusion injury. | Li W et al. | β | 2025 | β |
| Differential RELA and GR recruitment to the BIRC3/BIRC2 locus: Molecular insight as to combinatorial regulation by proinflammatory cytokines and glucocorticoid. | Thorne AJ et al. | β | 2025 | β |
| Discovery and Profiling of Protein Cysteine <i>S</i>-2-Carboxypropylation. | Song J et al. | β | 2025 | β |
| Discovery of lipid metabolism-related diagnostic biomarkers and construction of diagnostic model in steroid-induced osteonecrosis of femoral head. | Zuo B et al. | β | 2025 | β |
| Disrupting the interaction between connexin 43 and calmodulin restores gap junction function and mitigates reperfusion arrhythmias. | Wang L et al. | β | 2025 | β |
| Disruption of Swell1/VRAC function impairs initial hemodynamics and activates compensatory leukotriene signaling in zebrafish circulation development. | Tseng YT et al. | β | 2025 | β |
| Disruptions in gene interaction networks abolish host susceptibility to Trichostrongylus colubriformis infections in sheep. | Liu F et al. | β | 2025 | β |
| Diurnal rhythm of the human plasma proteome. | S JΓ³hΓΆnnuson EM et al. | β | 2025 | β |
| Divergent proteome tolerance against gain and loss of chromosome arms. | Di Y et al. | β | 2025 | β |
| DNA methylation insulates genic regions from CTCF loops near nuclear speckles. | Roseman SA et al. | β | 2025 | β |
| DNA repair and inflammatory response genes play a central role in protecting patients with long-standing type 1 diabetes from vascular complications. | ΓzgΓΌmΓΌΕ T et al. | β | 2025 | β |
| Domestication traits and adaptive evolution in blunt snout bream (Megalobrama amblycephala) by artificial selection pressure. | Cui Y et al. | β | 2025 | β |
| Double vulnerability of active-NRF2 lung squamous cell carcinoma to NRF2 and TRIM24. | SΓ‘nchez-Ortega M et al. | β | 2025 | β |
| Downregulation of AKT-mediated p27<sup>Kip1</sup> phosphorylation with shift to sphingomyelin synthesis in CLN3 disease. | Bilal F et al. | β | 2025 | β |
| Downregulation of Engulfment and cell motility 1 (Elmo1) induces quiescence and resistance to poly(I:C)-induced apoptosis in endothelial cells. | Kayashima Y et al. | β | 2025 | β |
| Drought inhibits thermomorphogenesis via salicylic acid-mediated suppression of ELF3 phase separation. | Song R et al. | β | 2025 | β |
| Duplication of the autism-related gene Chd8 leads to behavioral hyperactivity and neurodevelopmental defects in mice. | Kawamura A et al. | β | 2025 | β |
| Dying occurs as a defined molecular progression in <i>Drosophila</i> rather than as nonspecific physiological collapse. | Scott AW et al. | β | 2025 | β |
| Dynamic Compression Improves Chondrogenesis in the Tissue Engineered Model of Cartilage. | Farcasanu MV et al. | β | 2025 | β |
| Dynamic immune and molecular responses to chronic heat stress in blood and peripheral blood mononuclear cells of dairy cows. | Koch F et al. | β | 2025 | β |
| Dynamic landscape and regulation of m<sup>5</sup>C methylation in human tissues. | An K et al. | β | 2025 | β |
| Dynamic metabolic regulation of histone modifications during the yeast metabolic cycle. | GuzmΓ‘n-Dinamarca B et al. | β | 2025 | β |
| Dynamic Proteome Landscape During Preimplantation Human Embryo Development and Trophectoderm Stem Cell-Differentiation. | Rai A et al. | β | 2025 | β |
| Dysregulated Expression of Inflammasome and Extracellular Matrix Genes in <i>C9orf72</i>-ALS/FTD Microglia. | Thiry L et al. | β | 2025 | β |
| Dysregulated mitochondrial energy metabolism drives the progression of mucosal field effects to invasive bladder cancer. | Lee S et al. | β | 2025 | β |
| Early-life social isolation stress worsens compulsive- and anxiety-like behaviour and alters gene expression in the prefrontal cortex of SAPAP3 knockout mice. | Wilson C et al. | β | 2025 | β |
| Early proteomic response in thyroid gland after 131I administration in female Balb/c mice. | Rudqvist N et al. | β | 2025 | β |
| Early-stage lung adenocarcinoma affects DNA methylation and gene expression in adjacent tissues. | Wu Y et al. | β | 2025 | β |
| Early Transcriptomic Signatures of Immune Response Modulation Following Antiretroviral Therapy in HIV-Infected Patients. | Stolbova EA et al. | β | 2025 | β |
| Echs1-mediated histone crotonylation facilitates zygotic genome activation and expression of repetitive elements in early mammalian embryos. | Wang YF et al. | β | 2025 | β |
| ECM-based molecular subtypes define prognostic, EMT status, and therapeutic diversity in IDH-mutant gliomas. | Wei Y et al. | β | 2025 | β |
| Effect of Ipomoeassin F on the Synthesis of Membrane and Secretory Proteins in Triple-Negative Breast Cancer Cells. | Sicairos B et al. | β | 2025 | β |
| Effect of Topical Corticosteroid Treatment on microRNA Expression in Infants with Atopic Dermatitis. | Nousbeck J et al. | β | 2025 | β |
| Effect of ultrasound-microbubble exposure on acute myeloid leukemia cancer cell proteome. | Stilwell J et al. | β | 2025 | β |
| Effects of Dietary Sodium Modulation on Circulating Extracellular Vesicles. | Burrello J et al. | β | 2025 | β |
| Effects of legacy and emerging antimicrobial compounds to early-life stages of rainbow trout (Oncorhynchus mykiss). | Amekor M et al. | β | 2025 | β |
| Efficient gene set analysis for DNA methylation addressing probe dependency and bias. | Xu Z et al. | β | 2025 | β |
| Elucidating the landscape of genome-wide chromatin interaction sites of the lncRNA TUG1 in bovine cell lines and liver tissue. | Weikard R et al. | β | 2025 | β |
| Elucidating the therapeutic mechanisms of resveratrol in benign prostatic hyperplasia via an integrated strategy of network pharmacology, multi-omics and molecular biology. | Li J et al. | β | 2025 | β |
| Emerging roles of RNA-binding protein hnRNPM in alternative splicing regulation and UTMD mediated sh-hnRNPM/CMBs suppress the proliferation of colorectal cancer. | Hu Y et al. | β | 2025 | β |
| Endometrial Gene Expression Predicts Pregnancy Outcome in Brahman Cows. | Rocha CC et al. | β | 2025 | β |
| Endometriosis-associated infertility alters the microRNA signatures of cumulus cells with a particularly pronounced effect in oocytes that failed fertilization. | AlmiΓ±ana C et al. | β | 2025 | β |
| Endothelial c-REL orchestrates atherosclerosis at regions of disturbed flow through crosstalk with TXNIP-p38 and non-canonical NF-ΞΊB pathways. | Tardajos Ayllon B et al. | β | 2025 | β |
| Endothelial Nrf2 deficiency promotes atherosclerotic lesion formation by shaping a proinflammatory niche. | Sarad K et al. | β | 2025 | β |
| Endurance training promotes chromatin closure and timely repression of the post-exercise immediate early stress response. | de Smalen LM et al. | β | 2025 | β |
| Environmental Microbial Cues Alter Embryonic Development and Stress Responses in Vertebrates: Insights From the Zebrafish (Danio rerio) Model. | Green EM et al. | β | 2025 | β |
| Epigenetic regulation of individual components of combined hepatocellular-cholangiocarcinoma. | Schachtschneider KM et al. | β | 2025 | β |
| Epigenetic targeting of MECOM/KRAS axis by JIB-04 impairs tumorigenesis and cisplatin resistance in MECOM-amplified ovarian cancer. | Singh I et al. | β | 2025 | β |
| Epigenomics and transcriptomics profiles of developing zebrafish heart cells. | Chahal G et al. | β | 2025 | β |
| Establishment and Characterization of Bovine Trophoblast Stem Cells Growing as Adherent Cells or Vesicles. | Baquerre C et al. | β | 2025 | β |
| Evaluating Potential Therapeutic Targets and Drug Repurposing Based on the Esophageal Cancer Subtypes. | Oh J et al. | β | 2025 | β |
| Evaluation of the Circadian Rhythm Component Cipc (Clock-Interacting Pacemaker) in Leukemogenesis: A Literature Review and Bioinformatics Approach. | da Cunha LS et al. | β | 2025 | β |
| Examination of the lung and lymphoid tissue mRNA transcriptome response in dairy calves following experimental challenge with bovine alphaherpesvirus one (BoHV-1). | O'Donoghue S et al. | β | 2025 | β |
| Excessive DNA Double-Strand Breaks-Associated 3D Genome Reorganization Contributes to Neural Tube Defects with Folate Deficiency. | Zhang T et al. | β | 2025 | β |
| Exercise without Weight Loss Prevents Seasonal Decline in Vitamin D Metabolites: The VitaDEx Randomized Controlled Trial. | Perkin OJ et al. | β | 2025 | β |
| Exocyst subunits EXO70B1 and B2 contribute to stomatal dynamics and cell wall modifications. | Drs M et al. | β | 2025 | β |
| Expanding the CarD interaction network: CrsL is a novel transcription regulator in actinobacteria. | Shoman M et al. | β | 2025 | β |
| Exploration of Asparagus racemosus Willd for Alzheimer's Disease Through Integrated Metabolomics and Network Pharmacology Analyses Targeting BACE1 Protein. | Shaji V et al. | β | 2025 | β |
| Exploration of autophagy-related molecular mechanisms underlying epilepsy using multiple datasets. | Wang Y et al. | β | 2025 | β |
| Exploring the complex relationship between systemic lupus erythematosus and coronavirus disease 2019: genetic insights and potential protective mechanisms. | Xu X et al. | β | 2025 | β |
| Exploring the Epidemiology and Molecular Mechanisms of Riboflavin Against Chronic Kidney Disease Based on Data Mining, Single-Cell RNA Sequencing and Molecular Docking. | Liu Z et al. | β | 2025 | β |
| Exploring the interplay between circadian rhythms and obesity: A Boolean network approach to understanding metabolic dysregulation. | Cadena M et al. | β | 2025 | β |
| Exploring the key ingredients and mechanisms of Banxia Xiexin decoction for the treatment of polycystic ovary syndrome based on network pharmacology and experimental validation. | Hai B et al. | β | 2025 | β |
| Exploring the mechanism of methyl parathion and its degradation product on depression through network toxicology and molecular docking. | Cao M et al. | β | 2025 | β |
| Exploring the mechanism of PFTrDA on human hepatic metabolic diseases based on network toxicology and molecular docking. | Li Z et al. | β | 2025 | β |
| Exploring the molecular cargos associated with extracellular vesicles extracted from bone tissue to identify novel players in osteoblast function. | Binet F et al. | β | 2025 | β |
| Exploring the potential applications of whey protein hydrolysates in dairy processing: A study on bioactive peptides. | Chen Z et al. | β | 2025 | β |
| Exploring the Potentials of Silver Nanoparticles in Overcoming Cisplatin Resistance in Lung Adenocarcinoma: Insights from Proteomic and Xenograft Mice Studies. | Wong TY et al. | β | 2025 | β |
| Exploring the Potential Targets and Protective Agents in Mercury-Induced Anxiety Disorders Using Network Toxicology, Network Pharmacology, and Molecular Docking. | Farahani M et al. | β | 2025 | β |
| Exploring the regulatory mechanism of CCNA2 in colorectal cancer: Insights from multiomics and experimental analysis. | Lei X et al. | β | 2025 | β |
| Exploring the regulatory mechanisms of differentially expressed circRNAs during bovine intramuscular adipogenic differentiation. | Abebe BK et al. | β | 2025 | β |
| Extracellular ATP is an environmental cue in bacteria. | Tronnet S et al. | β | 2025 | β |
| Extracellular matrix alterations in chronic ischemic cardiomyopathy revealed by quantitative proteomics. | Buck KM et al. | β | 2025 | β |
| FAR1 as a ferroptosis-related biomarker and potential therapeutic target in acute kidney injury: integrated bioinformatics and experimental validation. | Duan H et al. | β | 2025 | β |
| Flavonoids of <i>S. suberectus Dunn</i> Regulate Cyclophosphamide-Induced Immunosuppression Through NF-ΞΊB Pathways. | Zhang J et al. | β | 2025 | β |
| FTO promotes post-stroke neuroprotection by m<sup>6</sup>A demethylation of c-Jun. | Chokkalla AK et al. | β | 2025 | β |
| Galangin and 1'-Acetoxychavicol Acetate from Galangal (<i>Alpinia galanga</i>) Suppress Lymphoma Growth via c-Myc Downregulation and Apoptosis Induction. | Moakmamern S et al. | β | 2025 | β |
| Galectin-3 in endometrial small extracellular vesicles promotes cytotrophoblast cell fusion during the implantation phase. | Ohara T et al. | β | 2025 | β |
| GBP2 condensates promote ferroptosis to sensitize anti-PD-L1 immunotherapy in melanoma. | Liu X et al. | β | 2025 | β |
| GeDi: simplifying gene set distances for enhanced omics interpretation in R/Bioconductor. | Nedwed AS et al. | β | 2025 | β |
| Gender differences in protein expression after polystyrene nanoplastics exposure in mussels Mytilus galloprovincialis. | GonΓ§alves JM et al. | β | 2025 | β |
| Gene age and genome organization in <i>Escherichia coli</i> and <i>Bacillus subtilis</i>. | Jers C et al. | β | 2025 | β |
| Generation of modified cows and sheep from spermatid-like haploid embryonic stem cells. | Yang L et al. | β | 2025 | β |
| Genes involved in lipid, carbohydrate and protein metabolic processes located in QTL regions affecting pork meat flavor. | Gregorio PD et al. | β | 2025 | β |
| Genes That Associated with Action of ACTH-like Peptides with Neuroprotective Potential in Rat Brain Regions with Different Degrees of Ischemic Damage. | Filippenkov IB et al. | β | 2025 | β |
| Genetic and transcriptional dysregulation of innate antiviral immune pathways in type 1 diabetes. | MΓΈnsted MΓ et al. | β | 2025 | β |
| Genetic architecture of a light-temperature coincidence detector. | Seluzicki A et al. | β | 2025 | β |
| Genetic assessment and Identification of genes related to characterization of Guangdong local goose breeds based on modern and historical genomes. | Zhang X et al. | β | 2025 | β |
| Genetic background and oncogenic driver determines the genomic evolution and transcriptomics of mammary tumor metastasis. | Ross CR et al. | β | 2025 | β |
| Genetic Inactivation of the Serotonin Transporter Dysregulates Expression of Neurotransmission Genes and Genome-Wide DNA Methylation Levels in the Medial Prefrontal Cortex of Male Rats During Postnatal Development. | Kroeze Y et al. | β | 2025 | β |
| Genetic markers associated with bone strength and density in Rhode Island Red laying hens. | Yue Q et al. | β | 2025 | β |
| Genetic relationship between SjΓΆgren's syndrome and abdominal aortic aneurysm: insights from a European population's genome-wide association analysis. | Zhou Y et al. | β | 2025 | β |
| Genetic silencing of K<sub>Ca</sub>3.1 inhibits atherosclerosis in ApoE null mice. | Alam P et al. | β | 2025 | β |
| Genome-Based Mexican Diet Bioactives Target Molecular Pathways in HBV, HCV, and MASLD: A Bioinformatic Approach for Liver Disease Prevention. | Leal-Mercado L et al. | β | 2025 | β |
| Genome-Wide Analysis of Copy Number Variations in Three Populations of Nanyang Cattle Using Whole-Genome Resequencing. | Dang D et al. | β | 2025 | β |
| Genome-Wide Association Studies and Candidate Genes for Egg Production Traits in Layers from an F<sub>2</sub> Crossbred Population Produced Using Two Divergently Selected Chicken Breeds, Russian White and Cornish White. | Volkova NA et al. | β | 2025 | β |
| Genome-Wide Association Studies in Japanese Quails of the F<sub>2</sub> Resource Population Elucidate Molecular Markers and Candidate Genes for Body Weight Parameters. | Volkova NA et al. | β | 2025 | β |
| Genome-Wide Association Study for Belly Traits in Canadian Commercial Crossbred Pigs. | Mozduri Z et al. | β | 2025 | β |
| Genome-Wide Association Study for Individual Primal Cut Quality Traits in Canadian Commercial Crossbred Pigs. | Mozduri Z et al. | β | 2025 | β |
| Genome-wide association study reveals genomic regions impacting yield-related traits in allohexaploid Brassica with AABBCC genomes. | Zhang K et al. | β | 2025 | β |
| Genome-wide CRISPRi screen and proteomic profiling identify key genes related to ferulic acid's antifungal activity. | Levi O et al. | β | 2025 | β |
| Genome wide DNA methylation and transcriptome integration analysis reveals potential markers in type A aortic dissection pathogenesis. | Chang C et al. | β | 2025 | β |
| Genome-Wide Egg Hunt: Unhiding Candidate Genes for Egg Component Traits in Layers of an F<sub>2</sub> Resource Population. | Volkova NA et al. | β | 2025 | β |
| Genome-wide identification of selection signals in fat-tailed and thin-tailed sheep populations. | Gao L et al. | β | 2025 | β |
| Genome-wide identification of the H3K27ac signals reveals key thermogenic cis-regulatory elements of brown adipose tissues in Oryctolagus cuniculus. | Du K et al. | β | 2025 | β |
| Genome-wide in vivo CRISPR screens identify GATOR1 complex as a tumor suppressor in Myc-driven lymphoma. | Potts MA et al. | β | 2025 | β |
| Genome-wide Screening of the Escherichia coli Keio Knockout Collection Identifies Genetic Determinants of Epetraborole Hypersusceptibility. | Babayeva A et al. | β | 2025 | β |
| Genome-Wide Screen using Escherichia coli Keio knockout mutant line reveals genes related to the antimicrobial properties of trans-Cinnamic Acid. | Sezer KΓΌrkΓ§ΓΌ M et al. | β | 2025 | β |
| Genome-wide SNP evidence for the genetic uniqueness of indigenous cattle population. | Chishi KG et al. | β | 2025 | β |
| Genome-Wide Study of Diabetes Mellitus (Type 2)-Associated Genes in Homo sapiens (Human). | Shaukat R et al. | β | 2025 | β |
| Genomic Analysis of Inbreeding Depression on Productive Traits in Rubia Galega Beef Cattle Breed. | Mejuto-VΓ‘zquez N et al. | β | 2025 | β |
| Genomic insights into runs of homozygosity, effective population size and selection signatures in Iranian meat and dairy sheep breeds. | Yousefi Z et al. | β | 2025 | β |
| Genomic insights into the demographic history and local adaptation of wild boars across Eurasia. | Wang Z et al. | β | 2025 | β |
| Genomic insights on the history and selection trajectories of the Comune di Sicilia goat. | Floridia V et al. | β | 2025 | β |
| Genomic resources and transcriptomic evidence of thermal stress in the southern saucer scallop (Ylistrum balloti). | Hook SE et al. | β | 2025 | β |
| Genomic structural equation modeling decodes skeletal aging: novel loci discovery and multisystem genetic crosstalk. | Zhou Y et al. | β | 2025 | β |
| Gentamicin induction of the gonococcal <i>hicAB</i> toxin-antitoxin-encoding system and impact on gene expression influencing biofilm formation and <i>in vivo</i> fitness in a strain-specific manner. | Holley CL et al. | β | 2025 | β |
| Ginkgo Seed as Medicine-Food Homology for Migraine: Network Pharmacology and Molecular Docking Insights. | Li Z et al. | β | 2025 | β |
| Ginsenoside Rh2-Liposome Potentiate Vaccine Immunity through Enhanced MHCβI Presentation. | Nie Q et al. | β | 2025 | β |
| Glial cells are involved in day-night protein dysregulation in the hippocampus of a mouse model of Alzheimer's disease. | Badina AM et al. | β | 2025 | β |
| Global analysis of excitotoxicity-induced alterations in RNA structure and RNA-protein binding in neurons. | Alvarez-Periel E et al. | β | 2025 | β |
| Global characterization of Dictyostelium discoideum gene and protein expression changes under hypoxic conditions. | Hesnard J et al. | β | 2025 | β |
| Global Transcriptomic Analysis Identifies Gene Expression Programs Regulated by Ξ±-Factor in Yeast. | Yeom S et al. | β | 2025 | β |
| Glucose-activated JMJD1A drives visceral adipogenesis via Ξ±-ketoglutarate-dependent chromatin remodeling. | Yang C et al. | β | 2025 | β |
| Glycoproteomics analysis of colorectal cancer reveals differential alterations of glycoproteins and glycans. | Zhang W et al. | β | 2025 | β |
| GPX1 and RCN1 as New Endoplasmic Reticulum Stress-Related Biomarkers in Multiple Sclerosis Brain Tissue and Their Involvement in the APP-CD74 Pathway: An Integrated Study Combining Machine Learning and Multi-Omics. | Qiao Z et al. | β | 2025 | β |
| Growth phase diets diminish histone acetyltransferase Gcn5 function and shorten lifespan of Drosophila males. | Mizutani S et al. | β | 2025 | β |
| GTX-11 improves portal hypertension, liver fibrosis, and sinusoidal cells phenotype in experimental MASH. | AndrΓ©s-Rozas M et al. | β | 2025 | β |
| Guided co-clustering transfer across unpaired and paired single-cell multi-omics data. | Li H et al. | β | 2025 | β |
| Gut microbiome-mediated epigenetic modifications in gastric cancer: a comprehensive multiomics analysis. | Qian Z et al. | β | 2025 | β |
| Gut microbiota mediates SREBP-1c-driven hepatic lipogenesis and steatosis in response to zero-fat high-sucrose diet. | Bergentall M et al. | β | 2025 | β |
| GΞ±13 Promotes Clonogenic Growth by Increasing Tolerance to Oxidative Metabolic Stress in Prostate Cancer Cells. | Wu D et al. | β | 2025 | β |
| HDAC11 Deacetylates BRAF to Regulate Kinase Activity and Cell Proliferation. | Madueke AC et al. | β | 2025 | β |
| hDPSC-derived Secretomes Enhance Odontogenic Differentiation and Suppress Inflammation: A Potential Cell-free Approach for Regenerative Endodontics. | Kim JS et al. | β | 2025 | β |
| Hepatic transcriptome profiling unveils candidate genes in cattle with liver abscesses under the influence of beef genetics in dairy cattle. | Felizari LD et al. | β | 2025 | β |
| Heterogeneity of Extracellular Vesicles and Non-Vesicular Nanoparticles in Glioblastoma. | Xu T et al. | β | 2025 | β |
| Heterogeneous subpopulations in <i>Escherichia coli</i> strains acquire adaptive resistance to imipenem treatment through rapid transcriptional regulation. | Luo Y et al. | β | 2025 | β |
| High-throughput DeepPRM-Stellar proteomics coupled with machine learning enables precise quantification of atherosclerosis-stroke progression biomarkers and risk prediction. | Liu Y et al. | β | 2025 | β |
| Histone H3 N-terminal recognition by the PHD finger of PHRF1 is required for proper DNA damage response. | Jain K et al. | β | 2025 | β |
| HMMR has oncoprotein-like properties in neuroblastoma cells and high HMMR expression has independent prognostic potential in neuroblastomas. | Karapouliou C et al. | β | 2025 | β |
| Honey bee (Apis mellifera) queen quality: host-microbial transcriptomes exploring the influence of age and hindgut symbiont Commensalibacter melissae. | Copeland DC et al. | β | 2025 | β |
| HPD is an RNA-Binding Protein Sustaining Ovarian Cancer Cell Glycolysis, Tumor Growth, and Drug Resistance. | Xie F et al. | β | 2025 | β |
| Human Extravillous Trophoblasts Require SRC-2 for Sustained Viability, Migration, and Invasion. | Maurya VK et al. | β | 2025 | β |
| Human papilloma virus infection drives unique metabolic and immune profiles in head and neck and cervical cancers: implications for targeted therapies and prognostic markers. | Hamid S et al. | β | 2025 | β |
| Hybrid Extracellular Vesicles With Combined Functional Properties From Mesenchymal Stem Cells and Astrocytes for Targeted Neurodegenerative Disease Applications. | Wang D et al. | β | 2025 | β |
| Hyperlipidemia-associated specific modules and hub genes revealed by integrative methods of WGCNA and MetaDE. | Zhao Z et al. | β | 2025 | β |
| Identification and functional annotation of candidate genes and transcription factors associated with reproductive traits to Nelore bulls: new insights from GWAS and post-GWAS analysis. | Silva EN et al. | β | 2025 | β |
| Identification and Validation of Differentially Expressed mRNAs From Peripheral Leukocytes for Acute Stanford Type A Aortic Dissection. | Zhou Y et al. | β | 2025 | β |
| Identification and Validation of Promising Targets and Inhibitors of Biofilm Formation in <i>Pseudomonas aeruginosa</i>: Bioinformatics, Virtual Screening, and Biological Evaluation. | Liang TT et al. | β | 2025 | β |
| Identification and validation of the important role of tryptophan-related gene CYP1B1 in the development and progression of sepsis. | Chen LH et al. | β | 2025 | β |
| Identification of a resistance-exercise-specific signalling pathway that drives skeletal muscle growth. | Zhu WG et al. | β | 2025 | β |
| Identification of biomarkers related to the progression of cutaneous melanoma and construction of survival prognosis model. | Chen K et al. | β | 2025 | β |
| Identification of Co-Diagnostic Genes and Potential Therapeutic Targets for Asthma and Sepsis Through Mendelian Randomization and Immune Infiltration Analysis. | Chen C et al. | β | 2025 | β |
| Identification of Differentially Expressed Genes in Spinal Cord Injury. | Chang A et al. | β | 2025 | β |
| Identification of Epigenetic Regulators of Vascular Calcification with a CRISPR-Based Screen. | Lian Y et al. | β | 2025 | β |
| Identification of Flavonoid Compounds in Treating Alzheimer's Disease Based on Network Medicine Framework Strategy. | Ding MR et al. | β | 2025 | β |
| Identification of Glutathione Synthetase as a Therapeutic Target for Cervical Cancer via Combining Bioinformatics and Experimental Validation. | Pan M et al. | β | 2025 | β |
| Identification of immune-related biomarkers associated with allergic rhinitis and development of a sample diagnostic model. | Wang M et al. | β | 2025 | β |
| Identification of metabolic reprogramming-related key genes in hepatocellular carcinoma after transcatheter arterial chemoembolization treatment. | Li T et al. | β | 2025 | β |
| Identification of microprotein-coding intronic polyadenylation isoforms and function in genotoxic anticancer drug response. | Devaux A et al. | β | 2025 | β |
| Identification of MRVI1-interacting proteins by biotin-based proximity labelling reveals NPM-ALK-dependent interaction dynamics. | Higashi K et al. | β | 2025 | β |
| Identification of Neurite Outgrowth and Synaptic Plasticity-related Genes Showing Sustained Hypermethylation of Promoter Region in the Hippocampal Dentate Gyrus of Rats Exposed Maternally To Neurotoxicants To Induce Persistent Disruption of Hippocampal Neurogenesis. | Ojiro R et al. | β | 2025 | β |
| Identification of plasma extracellular vesicle protein biomarkers in diabetic retinopathy progression. | Li Z et al. | β | 2025 | β |
| Identification of potential shared core biomarkers in type 2 diabetes and sarcopenia. | Zhang P et al. | β | 2025 | β |
| Identification of prognostic-related tumor microenvironment genes in lung adenocarcinoma and establishment of a prognostic prediction model. | Fang X et al. | β | 2025 | β |
| Identification of protein-coding genes associated with metastatic prostate cancer. | Sattari M et al. | β | 2025 | β |
| Identification of STN7-associated leaf senescence networks in thylakoid membranes of Arabidopsis. | Lee S et al. | β | 2025 | β |
| Identification of the LncRNA PRNCR1/miR-642a-5p/SSTR3 CeRNA network and its diagnostic value in type 2 diabetes mellitus. | Chen J et al. | β | 2025 | β |
| Identifying Common Diagnostic Biomarkers and Therapeutic Targets between COPD and Sepsis: A Bioinformatics and Machine Learning Approach. | Li X et al. | β | 2025 | β |
| Identifying common genes and immune infiltration characteristics between systemic sclerosis and atherosclerosis. | Pan Y et al. | β | 2025 | β |
| Identifying gene expression signatures of oncolytic virus response in patient-derived pancreatic ductal adenocarcinoma organoids. | Huberts M et al. | β | 2025 | β |
| Identifying key genes involved in HBV-related hepatocellular carcinoma: diagnose, prognosis, interaction and immune analysis. | Li Y et al. | β | 2025 | β |
| Identifying prognostic targets in metastatic prostate cancer beyond AR. | Feng E et al. | β | 2025 | β |
| Identifying pyroptosis- and inflammation-related genes in spinal cord injury based on bioinformatics analysis. | Xiang-Xia et al. | β | 2025 | β |
| Identify the therapeutic role and potential mechanism of Ξ±-cyperone in diminished ovarian reserve based on network pharmacology, molecular docking, Lip-MS and experimental validation. | Guo J et al. | β | 2025 | β |
| Immune factors produced by PBMCs upon stimulation with lactobacillus delbrueckii ssp. bulgaricus OLL1073R-1-derived exopolysaccharides inhibit HCoV-229E and SARS-CoV-2 replication. | Tang S et al. | β | 2025 | β |
| Immunomodulation of inflammatory responses preserves retinal integrity in murine models of pericyte-depletion retinopathy. | Kinuthia UM et al. | β | 2025 | β |
| Immunomodulatory inhibition of osteoclastogenesis by a marine microalgal ethanol fraction targeting T-cells, antigen presentation, and macrophage fate. | Carletti A et al. | β | 2025 | β |
| Immunophenotypic and Transcriptomic Analysis of Peripheral Blood Mononuclear Cells in Bullous Pemphigoid. | Choi J et al. | β | 2025 | β |
| Impact of Clove Oil on Biofilm Formation in <i>Candida albicans</i> and Its Effects on Mice with Candida Vaginitis. | Gao Y et al. | β | 2025 | β |
| Impact of schizophrenia-associated risk genes on brain functional networks and executive deficits: a study of individuals with schizophrenia and genetic high risk. | Sun T et al. | β | 2025 | β |
| Impaired cortical development and translational control in a missense mouse model of DDX3X syndrome. | Poff AJ et al. | β | 2025 | β |
| Inactivated <i>Rothia nasimurium</i> promotes a persistent antiviral immune status in porcine alveolar macrophages. | Tort-MirΓ³ A et al. | β | 2025 | β |
| Incorporating local ancestry information to predict genetically associated DNA methylation in admixed populations. | Cheng Y et al. | β | 2025 | β |
| Increased expression of the PIEZO2 mechanoreceptor in fibroblasts and endothelial cells within the lymphatic and vascular vessels of keloids. | Akita S et al. | β | 2025 | β |
| Increasing inflammatory biomarkers are associated with mortality in critically ill COVID-19 patients despite anti-inflammatory treatment. | Daenen K et al. | β | 2025 | β |
| In-Depth Cell-Type-Specific Proteome Landscape of the Brain from Human Amyloid-Ξ² Overexpression Mouse Model. | Ryu T et al. | β | 2025 | β |
| Indian Himalayan Arabidopsis thaliana population reflects deep history and might be the source of species expansion in the eastern edge. | Singh A et al. | β | 2025 | β |
| Inferring gene-pathway associations from consolidated transcriptome datasets: an interactive gene network explorer for <i>Tetrahymena thermophila</i>. | Bertagna MA et al. | β | 2025 | β |
| Inflammatory transcriptomic signatures in a human cellular NMOSD model reveal upregulation of NF-ΞΊB and IL6 pathways. | Brandl S et al. | β | 2025 | β |
| Influence of Pleurotus sapidus fruiting bodies on the performance, cecal microbiome, and gene expression in the liver and breast muscle of broilers. | SchΓ€fer L et al. | β | 2025 | β |
| Influence of sex and age on the gene expression of periodontal and pulp tissues during orthodontic tooth movement. | Zhao Z et al. | β | 2025 | β |
| Inhibiting HSCs Activation and Ameliorating Alcoholic Liver Fibrosis by Fucoidan Targeting the TLR4/NF-ΞΊB Pathway. | Wang G et al. | β | 2025 | β |
| Inhibition of p38-MK2 pathway enhances the efficacy of microtubule inhibitors in breast cancer cells. | Chen YC et al. | β | 2025 | β |
| Inhibition of Sirtuin 2 enhances autophagy and restores neuronal function in aged hippocampal neurons. | Zhang Z et al. | β | 2025 | β |
| Insights into the pathophysiology and response of persistent spinal pain syndrome type 2 to spinal cord stimulation: a human genome-wide association study. | Fabregat-Cid G et al. | β | 2025 | β |
| In Silico Analysis Reveals MDM2 as a Potential Target of Ursolic Acid for Overcoming Tamoxifen Resistance in Breast Cancer. | Jati YS et al. | β | 2025 | β |
| Integral approach to organelle profiling in human iPSC-derived cardiomyocytes enhances <i>in vitro</i> cardiac safety classification of known cardiotoxic compounds. | Szabo BR et al. | β | 2025 | β |
| Integrated multi-omics analyses of synaptosomes revealed synapse-associated novel targets in Alzheimer's disease. | Kumar S et al. | β | 2025 | β |
| Integrated multi-omics analysis of metabolome and transcriptome profiles during bovine adipocyte differentiation reveals functional divergence of FADS2 isoforms in lipid metabolism regulation. | Zhang X et al. | β | 2025 | β |
| Integrated multi-tissue transcriptomics reveals cross-tissue regulatory networks and hub genes regulating feed efficiency in aging chicken. | Han Y et al. | β | 2025 | β |
| Integrated network toxicology and transcriptomics analysis reveals the pathogenic mechanism linking volatile organic compounds exposure to rheumatoid arthritis. | Cheng Q et al. | β | 2025 | β |
| Integrated Transcriptomic and Proteomic Analysis of Omentin-1 Effects on Primary Anterior Pituitary Cells From Different Pig Breeds: An InΒ Vitro Study. | Respekta-DΕugosz N et al. | β | 2025 | β |
| Integrating reproductive states and social cues in the control of sociosexual behaviors. | Wang Y et al. | β | 2025 | β |
| Integrating single-cell and bulk RNA sequencing data establishes a cuproptosis-related gene predictive signature in breast cancer. | Peng R et al. | β | 2025 | β |
| Integrating whole-genome resequencing data reveals adaptive selection signatures in sheep populations under extreme environments. | Pang Z et al. | β | 2025 | β |
| Integration of a 4-gene risk score model enhances prognostic accuracy in acute myeloid leukemia. | Li Y et al. | β | 2025 | β |
| Integrative bioinformatic analysis identifies differentially expressed gene targets as potential biomarkers for anaplastic thyroid cancer. | TreviΓ±o-Juarez AS et al. | β | 2025 | β |
| Integrative bioinformatic and clinical validation reveals dynamic regulation of circulating microRNAs before and after antiretroviral therapy in HIV-positive patients. | Sonmez H et al. | β | 2025 | β |
| Integrin CD103 expression in naive CD8<sup>+</sup> T cells promotes cytokine-driven acquisition of memory phenotype and effector function. | Li C et al. | β | 2025 | β |
| Integrin Ξ²1 activity controls colony morphology during human pluripotent stem cell state transitions. | Taskinen ME et al. | β | 2025 | β |
| Interaction of matrix components and cells regulating cellular and molecular processes of glioma cells. | Yao L et al. | β | 2025 | β |
| Interactome of FMRP-N-tat therapeutic unveils key interactions for cellular function in Fragile X neurons. | Leguay K et al. | β | 2025 | β |
| Investigating miR-30a's tumor suppressor role and its targets (MYBL2, TWF1, GALNT7, PFN2) as prognostic biomarkers in lung adenocarcinoma. | Sahin Y et al. | β | 2025 | β |
| Investigating the differential microRNAs expression in young and aged <i>Drosophila melanogaster</i> following Flock House Virus infection. | Thibeaux A et al. | β | 2025 | β |
| Investigating the Mechanisms of <i>Lycii fructus</i> in Treating Nonalcoholic Fatty Liver Disease and Diabetes Comorbidity Through Network Pharmacology and Molecular Dynamics. | Sun P et al. | β | 2025 | β |
| Investigating the molecular mechanisms of the "Astragalus-Codonopsis" herb pair in treating diabetes: a network pharmacology and bioinformatics approach with molecular docking validation. | Yang J et al. | β | 2025 | β |
| Investigation of Antithrombotic Activity and In Vivo Effective Forms of Kaempferitrin Using FeCl<sub>3</sub>-Induced Rat Arterial Thrombosis and UHPLC-Q-Exactive Orbitrap MS. | Zhou J et al. | β | 2025 | β |
| Investigation of the toxicological effects of PFAS on cholangiocarcinoma based on network toxicology, bioinformatics, and molecular docking. | Sun H et al. | β | 2025 | β |
| Investigations on bioactive compounds of Punica granatum and Beta vulgaris for breast cancer treatment: Network pharmacology predictions, molecular docking, and in-vitro experimental verification of radiation-sensitizing effects. | Sukumaran N et al. | β | 2025 | β |
| In Vitro Bioactivity of a Recombinant Human Collagen Peptide in a Filler Biomimetic Skin Model. | He C et al. | β | 2025 | β |
| In vitro HIV DNA integration in STAT3 drives T cell persistence-A model of HIV-associated T cell lymphoma. | Rist M et al. | β | 2025 | β |
| In vivo imaging reveals exosome-mediated intercellular communication in lens development. | Ma J et al. | β | 2025 | β |
| In vivo transition in chromatin accessibility during differentiation of deep-layer excitatory neurons in the neocortex. | Sakai S et al. | β | 2025 | β |
| Iron supplementation protects against renal ischemia-reperfusion injury by enhancing mitochondrial respiratory complex assembly. | Qi Y et al. | β | 2025 | β |
| Isoform differences drive functional diversity of NHR-49. | Tatge L et al. | β | 2025 | β |
| [Isolation and proteomics analysis of cerebrospinal fluid exosome subtypes]. | Chen XF et al. | β | 2025 | β |
| Jasmonate pathway regulates sphingolipid desaturation during cold stress. | Huang LQ et al. | β | 2025 | β |
| Jet lag-induced circadian disruption elevates glioma risk by altering molecular profiles in distinct brain regions. | Zhang Y et al. | β | 2025 | β |
| Jiedu Tongluo Tiaogan Formula Modulates Glycolipid Metabolism in Type 2 Diabetes via Pyroptosis: Network Pharmacology and InΒ Vivo Analysis. | Jing S et al. | β | 2025 | β |
| Joint Microbiota Suggests Articular Dysbiosis in Experimental Murine Spondyloarthritis and Histological Detection of Bacteria in Human SpA Joints. | GonzΓ‘lez-ChΓ‘vez SA et al. | β | 2025 | β |
| KDM3A and KDM3B regulate alternative splicing in mouse pluripotent stem cells. | Dillingham CM et al. | β | 2025 | β |
| KEAP1 retention in phase-separated p62 bodies drives liver damage under autophagy-deficient conditions. | Takada S et al. | β | 2025 | β |
| Keratin-Mediated Selective Inhibition in Proliferation and Selective Apoptosis of Keloid Fibroblasts. | Kang HJ et al. | β | 2025 | β |
| KHDC3 affects the lineage differentiation of early embryo by regulating the differential distribution of YAP signal. | Xu Q et al. | β | 2025 | β |
| KIAA1522 isoform switching regulates LTR-RTs activity in distinct pluripotency states of hESCs. | Yang N et al. | β | 2025 | β |
| Klf5-adjacent super-enhancer functions as a 3D genome structure-dependent transcriptional driver to safeguard ESC identity. | Su G et al. | β | 2025 | β |
| Knockdown of USF1 and USF2 drives prolonged changes in the gene expression response of M12-5B3 cells to DNA damage. | Bellingham-Johnstun KS et al. | β | 2025 | β |
| KnowYourCG: Facilitating base-level sparse methylome interpretation. | Goldberg DC et al. | β | 2025 | β |
| Lamin A/C Expression in Hematopoietic Cells Declines During Human Aging and Constrains Atherosclerosis in Mice. | AmorΓ³s-PΓ©rez M et al. | β | 2025 | β |
| Land plant-specific H3K27 methyltransferases ATXR5 and ATXR6 control plant development and stress responses. | Li X et al. | β | 2025 | β |
| Large MAF transcription factors reawaken evolutionarily dormant fast-glycolytic type IIb myofibers in human skeletal muscle. | Sadaki S et al. | β | 2025 | β |
| Light-evoked activity and BDNF regulate mitochondrial dynamics and mitochondrial localized translation in CNS axons. | Kreymerman A et al. | β | 2025 | β |
| Liquid Biopsy-Based DNA Methylation Biomarkers for Precision Medicine in Breast Cancer. | Sadzeviciene I et al. | β | 2025 | β |
| Liquid Biopsy-Multiomics Link Adhesion Pathway Dysregulation to Kidney Injury Severity. | Anandakrishnan N et al. | β | 2025 | β |
| LncRNA Subcellular Localization Across Diverse Cell Lines: An Exploration Using Deep Learning with Inexact <i>q</i>-mers. | Yi W et al. | β | 2025 | β |
| Local peptide signalling induces stomatal closure under drought stress. | Shimotohno A et al. | β | 2025 | β |
| Long non-coding RNA NORAD serves as a promoter of oncogenesis and inhibits ferroptosis via miR-144-3p-mTOR-ferritinophagy axis in cancer. | Zhang X et al. | β | 2025 | β |
| Loss of ALK4 promotes cancer progression through regulating TGF-Ξ² receptor N-glycosylation. | Zhang M et al. | β | 2025 | β |
| Loss of Ezrin triggers mitochondrial dysfunction and oxidative stress, associated with neuronal cell death. | Giamundo G et al. | β | 2025 | β |
| Loss of the ESX-5 secretion locus in <i>Mycobacterium tuberculosis</i> reshapes the mycomembrane and enhances ESX-1 substrate secretion. | Koleske B et al. | β | 2025 | β |
| Loss of the <i>PPE71-esxX-esxY-PPE38</i> locus drives adaptive transcriptional responses and hypervirulence of <i>Mycobacterium tuberculosis</i> lineage 2. | Koleske B et al. | β | 2025 | β |
| Low-temperature plasma modulates seed germination through reactive oxygen species in dose-dependent manner. | Park S et al. | β | 2025 | β |
| Lrtm1: A Novel Sensor of Insulin Signaling and Regulator of Metabolism and Activity. | Yu Y et al. | β | 2025 | β |
| <i>B3GNT3</i> is an oncogenic and prognostic biomarker in human tumors via pan-cancer analysis combined with experimental validation. | Shen K et al. | β | 2025 | β |
| <i>In Vitro</i> and <i>Ex Vivo</i> evidence that pharmacological induction of the hypoxia response pathway efficiently restricts measles and Nipah virus infections. | Canus L et al. | β | 2025 | β |
| <i>Jianpi-Huayu-Jiedu</i> formula improves metabolic dysfunction-associated steatohepatitis through ameliorateing hepatic oxidative stress and lipid accumulation <i>in vivo</i> and <i>in vitro</i>. | Wu X et al. | β | 2025 | β |
| <i>p21</i>, <i>ccng1</i>, <i>foxo3b</i>, and <i>fbxw7</i> contribute to <i>p53</i>-dependent cell cycle arrest. | Wang J et al. | β | 2025 | β |
| <i>Schisandra chinensis</i> alleviates Hypertriglyceridemia in nonalcoholic fatty liver disease by modulating the gut microbiota and hepatic lipid metabolism: identification of its active fractions. | Li Q et al. | β | 2025 | β |
| <i>Zic3</i> represses anterior digit development in tetrapods. | Li SS et al. | β | 2025 | β |
| <sup>161</sup>Tb Radioimmunotherapy as a Treatment for CD30-Positive Lymphomas. | Rioja-Blanco E et al. | β | 2025 | β |
| Luminal Cerebrovascular Proteomics. | Shi SM et al. | β | 2025 | β |
| Lymphopenia, IL6, and CCL2 after thoracic radiotherapy predict poor prognosis in patients with lung cancer. | Chen JL et al. | β | 2025 | β |
| Machine Learning-Based identification of resistance genes associated with sunflower broomrape. | Che Y et al. | β | 2025 | β |
| Machine learning-enabled identification of nucleus pulposus senescence-associated genes as potential biomarkers for intervertebral disc degeneration. | Xiang M et al. | β | 2025 | β |
| Male caregiving experience alters hippocampal neuroplasticity and transcription independent of reproduction in a biparental species. | Colt ME et al. | β | 2025 | β |
| Mapping the placental galectin-3 interactome identifies CD9 and ITGB1 as functional glycoprotein counterreceptors during syncytialization. | Reeves AE et al. | β | 2025 | β |
| Mechanically-adaptive, resveratrol-eluting neural probes for improved intracortical recording performance and stability. | Mueller NN et al. | β | 2025 | β |
| Mechanisms of Cisplatin-Induced Acute Kidney Injury: The Role of NRF2 in Mitochondrial Dysfunction and Metabolic Reprogramming. | Liu J et al. | β | 2025 | β |
| Meiotic cohesin RAD21L shapes 3D genome structure and transcription in the male germline. | MarΓn-Gual L et al. | β | 2025 | β |
| Melatonin and spermidine protect early mouse embryos from ethylparaben toxicity by restoring histone modifications and subcellular structures. | Wang YF et al. | β | 2025 | β |
| Melatonin at Crossroads with Phytohormones: Interactions Under High Light Stress. | Bychkov IA et al. | β | 2025 | β |
| Melatonin modulates the gene expression of WEE1 kinase and clock genes: a crosstalk between the molecular clocks of the placenta? | Venegas C et al. | β | 2025 | β |
| Mendelian randomization study implicates inflammaging biomarkers in retinal vasculature, cardiovascular diseases, and longevity. | Villaplana-Velasco A et al. | β | 2025 | β |
| Mepolizumab alters gene regulatory networks of nasal airway type-2 and epithelial inflammation in urban children with asthma. | Gaberino CL et al. | β | 2025 | β |
| Meta-analysis of RNA-seq Data Identifies Involvement of Interferon-Induced Genes to Facilitate Blood-Brain Barrier Traversal of Neuroinvasive Pathogens. | Kulkarni A et al. | β | 2025 | β |
| Metabolic and immune functions of the hemolymph and fat body in Hermetia illucens (Diptera: Stratiomyidae) under pathogen challenge. | Herman N et al. | β | 2025 | β |
| Metformin alters liver metabolism to sustain egg production in the reproductively aging broiler breeder henβ . | Weaver EA et al. | β | 2025 | β |
| Micheliolide mitigates diabetic nephropathy by modulating oxidative stress and inflammation in rats. | Zhang C et al. | β | 2025 | β |
| Microarray profile of circular RNAs identifies CBT15_circR_28491 and T helper cells as new regulators for deep vein thrombosis. | Chen W et al. | β | 2025 | β |
| Microgravity accelerates skeletal muscle degeneration: Functional and transcriptomic insights from an ISS muscle lab-on-chip model. | Parafati M et al. | β | 2025 | β |
| MicroRNA-142-3p shuttling in extracellular vesicles marks regulatory T cell dysfunction in multiple sclerosis. | De Rosa G et al. | β | 2025 | β |
| MicroRNA-592 suppresses breast cancer progression by targeting CYP20A1 to modulate the CHOP pathway. | Pan R et al. | β | 2025 | β |
| MicroRNA-driven evolutionary pressure in SARS-CoV-2: the role of hsa-miR-6512 in mutational dynamics. | Razban P et al. | β | 2025 | β |
| microRNA Expression in the Late Embryonic Pax6-Null Mouse Cerebellum. | Abdalla-Wyse A et al. | β | 2025 | β |
| MicroRNA mediated regulation in early-onset cardiac hypertrophy: Insights from the hypertrophic heart rat model. | Sadiq S et al. | β | 2025 | β |
| MicroRNAs and rs1803274 SNP-based BuChe downregulation are associated with metabolic syndrome through ghrelin hydrolysis and expression quantitative trait loci regulation in PD patients. | Chevalier G et al. | β | 2025 | β |
| MicroRNAs regulate alveolar macrophage homeostasis and its function in lung fibrosis. | Parajuli N et al. | β | 2025 | β |
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| Mir-16 Decreases the Expression of VTI1B and SMPD1, Genes Involved in Membrane-Protein Trafficking in Melanoma. | Layani A et al. | β | 2025 | β |
| miR-210 promotes the anti-inflammatory phenotype and M2 polarization in murine macrophages. | Neculachi CA et al. | β | 2025 | β |
| miR-221/222-3p act as potential circulating factors in heart failure to stimulate cancer progression. | Xu R et al. | β | 2025 | β |
| miR-423-5p and miR-92a-3p in Alzheimer's disease: relationship with pathology and cognition. | Han SW et al. | β | 2025 | β |
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| miRNA-200a suppresses GNAI1 and PLCB4 to modulate skin pigmentation in cashmere goats. | Li J et al. | β | 2025 | β |
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| Mitochondrial Translation Inhibition Triggers an Rst2-Controlled Transcriptional Reprogramming of Carbon Metabolism in Stationary-Phase Cells of Fission Yeast. | Luo Y et al. | β | 2025 | β |
| Mitochondria-mediated retrograde responses evoked by inhibitor antimycin A and mtDNA elimination in Chlamydomonas reinhardtii. | Khan A et al. | β | 2025 | β |
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| Molecular Signatures of Early-Onset Bipolar Disorder and Schizophrenia: Transcriptomic and Machine-Learning Insights into Calcium and cAMP Signaling, Including Sex-Specific Patterns. | Afjeh SS et al. | β | 2025 | β |
| Mollugin attenuates oxygen-glucose deprivation/reperfusion-induced brain microvascular endothelial cell death and permeability through activation of BDNF/TrkB-modulated Akt pathway. | Jia X et al. | β | 2025 | β |
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| Network Pharmacology and Molecular Docking-Based Approach to Explore Potential Bioactive Compounds from <i>Kaempferia parviflora</i> on Chemokine Signaling Pathways in the Treatment of Psoriasis Disease. | Sakuludomkan C et al. | β | 2025 | β |
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| The inhibition of de novo purine synthesis increases LAMP2 expression to preserve cell viability. | De Cristofaro A et al. | β | 2025 | β |
| The Kinase Inhibitor GNF-7 Is Synthetically Lethal in Topoisomerase 1-Deficient Ewing Sarcoma. | Sayers CM et al. | β | 2025 | β |
| The knockout of Moesin leads to excess microglia-mediated synaptic pruning and impairs social novelty in a mouse model. | Lai W et al. | β | 2025 | β |
| The metabolic advantage of being young and male in obesity treatment outcomes in mice. | Dirnberger AS et al. | β | 2025 | β |
| The METTL3-YTHDC1 axis mediates architectural RNA m<sup>6</sup>A modification to modulate the integrity of chromatin TADs in MLLrβ+βAML genome. | Fu R et al. | β | 2025 | β |
| The muscle specific MEF2DΞ±2 isoform promotes muscle ketolysis and running capacity in mice. | Kumar S et al. | β | 2025 | β |
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| The patient-specific mouse model with Foxg1 frameshift mutation provides insights into the pathophysiology of FOXG1 syndrome. | Jeon S et al. | β | 2025 | β |
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| The proteomic and transcriptomic profiles of gastric mucosa from health volunteers. | An Y et al. | β | 2025 | β |
| The Radioprotective Effects of 16, 16 dimethyl Prostaglandin E2 on Survival and Hematopoiesis are Mediated Through Co-Stimulation of the EP3 and EP4 Receptors. | Fukuda S et al. | β | 2025 | β |
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| The RNA m<sup>6</sup>A landscape during human oocyte-to-embryo transition. | Li Y et al. | β | 2025 | β |
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| To reveal the key mechanism of Citri Reticulatae Pericarpium-Reynoutria japonica Houtt in the treatment of liver cancer and its correlation with lipid metabolism: synergetic effect with network pharmacology, molecular docking and bioinformatics. | Lin C et al. | β | 2025 | β |
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| Transcriptional Profiling of Common Carp: A Microarray-Based Framework for Aquaculture Research. | Pluta A et al. | β | 2025 | β |
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| Transcriptome analysis identifies CCR7 and cell adhesion molecules as mediators of B cell migration to the bursa of Fabricius during chicken embryonic development. | Brunner M et al. | β | 2025 | β |
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| Transcriptomic Alterations of Canine Histiocytic Sarcoma Cells in Response to Different Stressors. | Asawapattanakul T et al. | β | 2025 | β |
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| Transcriptomic Changes in the Frontal Cortex of Juvenile Pigs with Diet-Induced Metabolic Dysfunction-Associated Liver Disease. | Mahon K et al. | β | 2025 | β |
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| Transcriptomic insights into the healthspan-enhancing effects of C. chinensis seed and E. ulmoides bark extracts in Caenorhabditis elegans. | Sayed SMA et al. | β | 2025 | β |
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| Unraveling the immunosuppressive role of Elastase B produced by cystic fibrosis isolates of <i>Pseudomonas aeruginosa</i> in an organotypic 3D lung epithelial cell model. | Wauters M et al. | β | 2025 | β |
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| Whole-Genome Resequencing Analysis of Copy Number Variations Associated with Athletic Performance in Grassland-Thoroughbred. | Ding W et al. | β | 2025 | β |
| Whole-Genome Sequencing Identifies Functional Genes for Environmental Adaptability in Chinese Geese. | Ren X et al. | β | 2025 | β |
| Whole-genome sequencing reveals patterns of runs of homozygosity underlying genetic diversity and selection in domestic rabbits. | Ping X et al. | β | 2025 | β |
| Whole-tree dormancy dynamics in peach: Carbohydrate reservoirs and crosstalk with hormones and fatty acids. | Jahed KR et al. | β | 2025 | β |
| Zinc eluted from glassware is a risk factor for embryo development in human and animal assisted reproductionβ . | Yao T et al. | β | 2025 | β |
| Ξ² Cell GΞ±s signaling is critical for physiological and pharmacological enhancement of insulin secretion. | Capozzi ME et al. | β | 2025 | β |