Psychiatric comorbidity in methamphetamine dependence.
paper
Cited
Public
- Authors
- Salo, Ruth; Flower, Keith; Kielstein, Anousheh; Leamon, Martin H; Nordahl, Thomas E; Galloway, Gantt P
- Year
- 2011
- Journal
- Psychiatry research
- PMID
- 21055832
- DOI
- 10.1016/j.psychres.2010.09.014
- PMCID
- PMC3058719
The primary aim of the present study was to assess the prevalence of psychiatric comorbidity in a large sample of methamphetamine (MA)-dependent subjects using a validated structured clinical interview, without limitation to sexual orientation or participation in a treatment program. The secondary aim was to assess whether the prevalence of psychiatric comorbidities varied by gender. Structured clinical interviews (SCIDs) were administered to 189 MA-dependent subjects and lifetime prevalence of DSM-IV diagnoses was assessed. Across the sample, 28.6% had primary psychotic disorders, 23.8% of which were substance-induced; 13.2% had MA-induced delusional disorders and 11.1% had MA-induced hallucinations. A substantial number of lifetime mood disorders were identified that were not substance-induced (32.3%), whereas 14.8% had mood disorders induced by substances, and 10.6% had mood disorders induced by amphetamines. Of all participants, 26.5% had anxiety disorders and 3.7% had a substance-induced anxiety disorder, all of which were induced by MA. Male subjects reported a higher percentage of MA-induced delusions compared to female abusers. Given the impact of MA psychosis and other drug-induced symptoms on hospitals and mental health services, the description and characterization of comorbid psychiatric symptoms associated with MA use is of paramount importance.
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Next β
| Name | Type |
|---|---|
| addiction | phenotype |
| Adolescent methamphetamine abusers local | cohort |
| adolescents | cohort |
| alcohol | phenotype |
| amphetamine | drug |
| amphetamine-type stimulants | drug |
| Amphetamine use disorder | phenotype |
| anxiety | phenotype |
| Australian MA users local | cohort |
| axis I disorder | phenotype |
| bipolar disorder | phenotype |
| Brecht et al. 2004 cohort local | cohort |
| cannabis use | phenotype |
| Caucasian | cohort |
| Caucasians | cohort |
| Chen et al. 2003 cohort local | cohort |
| cocaine | phenotype |
| Cocaine-using persons local | cohort |
| Cohort_1580_arrestees_MA_dependence local | cohort |
| Cohort_31_non_users local | cohort |
| Cohort_46_MA_users local | cohort |
| Cohort_51_MA_users_minimal_contact local | cohort |
| Cohort_55_MA_users_mixed_population local | cohort |
| Co-occurring psychiatric disorder local | phenotype |
| Delusional disorder local | phenotype |
| delusions | phenotype |
| depression | phenotype |
| drug dependence | phenotype |
| drug-induced disorder local | phenotype |
| DSM-IV | phenotype |
| Early MA use local | phenotype |
| General drug-using population local | cohort |
| generalized anxiety disorder | phenotype |
| genetic factors | cohort |
| Hall et al. 1996 Australian study local | cohort |
| hallucinations | phenotype |
| Heterosexual local | phenotype |
| High MA consumption local | phenotype |
| Hospital readmission local | phenotype |
| Lin et al. 2004 cohort local | cohort |
| MA-abstinent local | cohort |
| MA abusers local | cohort |
| MA abusers cohort local | cohort |
| MA abusers cohort (Nakama 2008) local | cohort |
| MA abusers cohort (Sommers 2006) local | cohort |
| MA/Cocaine dependent cohort (Mahoney 2008) local | cohort |
| MA dependent cohort (Leamon 2010) local | cohort |
| MA-dependent individuals local | cohort |
| MA-dependent samples local | cohort |
| MA-dependent subjects local | cohort |
| MA-induced delusional disorder local | phenotype |
| MA-induced delusions local | phenotype |
| MA-induced disorder local | phenotype |
| MA-induced hallucinations local | phenotype |
| MA-induced paranoia local | phenotype |
| MA-induced psychosis local | phenotype |
| MA-induced psychotic disorder | phenotype |
| major depressive disorder | phenotype |
| MA treatment cohort local | cohort |
| MA users local | cohort |
| men | cohort |
| methamphetamine | drug |
| Methamphetamine Abuse local | phenotype |
| methamphetamine dependence | phenotype |
| Methamphetamine-dependent users local | cohort |
| methamphetamine-induced psychosis local | phenotype |
| Methamphetamine Treatment Program local | cohort |
| Methamphetamine Treatment Project cohort local | cohort |
| mood disorders | phenotype |
| MTP follow-up study local | cohort |
| National Epidemiologic Survey on Alcohol and Related Conditions | cohort |
| NESARC | cohort |
| nicotine | drug |
| Non-clinical MA-dependent cohort local | cohort |
| non-drug-induced psychotic disorder local | phenotype |
| Non-heterosexual individuals local | cohort |
| Non-substance-induced psychiatric disorders local | phenotype |
| opiates | drug |
| Other disorder local | phenotype |
| other drugs | drug |
| other substances | phenotype |
| panic disorder | phenotype |
| paranoia | phenotype |
| People worldwide (2007) local | cohort |
| Post-Traumatic Stress Disorder | phenotype |
| psychiatric disorders | phenotype |
| Psychiatric hospital admission local | phenotype |
| psychiatric hospitalization local | phenotype |
| psychiatric symptoms | phenotype |
| psychosis | phenotype |
| Publically-funded substance abuse treatment programs (US) local | cohort |
| relapse | phenotype |
| Schizoid/schizotypal personality traits local | phenotype |
| schizophrenia | phenotype |
| Separated/divorced local | phenotype |
| severe anxiety local | phenotype |
| sex | phenotype |
| sex differences | phenotype |
| Shoptaw study local | cohort |
| Single and never married local | phenotype |
| social dysfunction | phenotype |
| study cohort | cohort |
| Study of 146 heterosexual female MA users local | cohort |
| substance-induced anxiety disorders local | phenotype |
| substance-induced disorder local | phenotype |
| Substance-induced disorder local | phenotype |
| substance-induced disorders local | phenotype |
| Substance-induced mood disorders local | phenotype |
| Substance-induced psychiatric disorders local | phenotype |
| substance use | phenotype |
| suicide | phenotype |
| Taiwanese MA users cohort local | cohort |
| Thailand MA cohort local | cohort |
| treatment response | phenotype |
| United States | cohort |
| women | cohort |
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