Whole-genome association study of bipolar disorder.
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- Authors
- Sklar, P; Smoller, J W; Fan, J; Ferreira, M A R; Perlis, R H; Chambert, K; Nimgaonkar, V L; McQueen, M B; Faraone, S V; Kirby, A; de Bakker, P I W; Ogdie, M N; Thase, M E; Sachs, G S; Todd-Brown, K; Gabriel, S B; Sougnez, C; Gates, C; Blumenstiel, B; Defelice, M; Ardlie, K G; Franklin, J; Muir, W J; McGhee, K A; MacIntyre, D J; McLean, A; VanBeck, M; McQuillin, A; Bass, N J; Robinson, M; Lawrence, J; Anjorin, A; Curtis, D; Scolnick, E M; Daly, M J; Blackwood, D H; Gurling, H M; Purcell, S M
- Year
- 2008
- Journal
- Molecular psychiatry
- PMID
- 18317468
- DOI
- 10.1038/sj.mp.4002151
- PMCID
- PMC3777816
We performed a genome-wide association scan in 1461 patients with bipolar (BP) 1 disorder, 2008 controls drawn from the Systematic Treatment Enhancement Program for Bipolar Disorder and the University College London sample collections with successful genotyping for 372,193 single nucleotide polymorphisms (SNPs). Our strongest single SNP results are found in myosin5B (MYO5B; P=1.66 x 10(-7)) and tetraspanin-8 (TSPAN8; P=6.11 x 10(-7)). Haplotype analysis further supported single SNP results highlighting MYO5B, TSPAN8 and the epidermal growth factor receptor (MYO5B; P=2.04 x 10(-8), TSPAN8; P=7.57 x 10(-7) and EGFR; P=8.36 x 10(-8)). For replication, we genotyped 304 SNPs in family-based NIMH samples (n=409 trios) and University of Edinburgh case-control samples (n=365 cases, 351 controls) that did not provide independent replication after correction for multiple testing. A comparison of our strongest associations with the genome-wide scan of 1868 patients with BP disorder and 2938 controls who completed the scan as part of the Wellcome Trust Case-Control Consortium indicates concordant signals for SNPs within the voltage-dependent calcium channel, L-type, alpha 1C subunit (CACNA1C) gene. Given the heritability of BP disorder, the lack of agreement between studies emphasizes that susceptibility alleles are likely to be modest in effect size and require even larger samples for detection.
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| Title | Authors | Journal | Year | Link |
|---|---|---|---|---|
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| Whole-genome sequence-based association analysis of African American individuals with bipolar disorder and schizophrenia. | Li R et al. | β | 2026 | β |
| Diagnostic parallels between borderline and bipolar patients in psychopathology: Similarities, differences, comorbidities, neural correlates, and a new proposal for the Perrotta Border-Bipolar Profile Diagnostic Questionnaire. | Perrotta G et al. | β | 2025 | β |
| Genomics of Bipolar Disorder: What the Clinician Needs to Know. | McQuillin A et al. | β | 2025 | β |
| The Impact of Overexpression of the Mouse Ortholog of <i>CACNA1C</i> on Behavior and Cortical Dynamics. | Parent R et al. | β | 2025 | β |
| Transdiagnostic findings across major depressive disorder, bipolar disorder and schizophrenia: A qualitative review. | Stein F et al. | β | 2025 | β |
| Association of 11 variants of the dopaminergic and cognitive pathways genes with major depression, schizophrenia and bipolar disorder in the Pakistani population. | Nasir Hashmi A et al. | β | 2024 | β |
| Classical cadherins evolutionary constraints in primates is associated with their expression in the central nervous system. | Petersen M et al. | β | 2024 | β |
| Differential serum levels of CACNA1C, circadian rhythm and stress response molecules in subjects with bipolar disorder: Associations with genetic and clinical factors. | Allen O et al. | β | 2024 | β |
| Differential Serum Levels of CACNA1C, Circadian Rhythm and Stress Response Molecules in Subjects with Bipolar Disorder: Associations with Genetic and Clinical Factors | Allen O et al. | β | 2024 | β |
| Human-Induced Pluripotent Stem Cell (iPSC)-Derived GABAergic Neuron Differentiation in Bipolar Disorder. | Schill DJ et al. | β | 2024 | β |
| Involvement of the Na<sup>+</sup>, K<sup>+</sup>-ATPase Ξ±1 Isoform and Endogenous Cardiac Steroids in Depression- and Manic-like Behaviors. | Horesh N et al. | β | 2024 | β |
| L-type calcium channel regulation of depression, anxiety and anhedonia-related behavioral phenotypes following chronic stress exposure. | Nunes EJ et al. | β | 2024 | β |
| Normative modelling of molecular-based functional circuits captures clinical heterogeneity transdiagnostically in psychiatric patients. | Lawn T et al. | β | 2024 | β |
| Sex-Specific Mechanisms Underlie Long-Term Potentiation at HippocampusβMedium Spiny Neuron Synapses in the Medial Shell of the Nucleus Accumbens. | Copenhaver AE et al. | β | 2024 | β |
| Antihypertensive drugs and brain function: mechanisms underlying therapeutically beneficial and harmful neuropsychiatric effects. | Carnovale C et al. | β | 2023 | β |
| CACNA1C-Related Channelopathies. | Herold KG et al. | β | 2023 | β |
| Genetic Architecture of Ischaemic Strokes after COVID-19 Shows Similarities with Large Vessel Strokes. | LluciΓ -Carol L et al. | β | 2023 | β |
| Genetics of bipolar disorder: insights into its complex architecture and biology from common and rare variants. | Hara T et al. | β | 2023 | β |
| L-type calcium channel regulation of dopamine activity in the ventral tegmental area to nucleus accumbens pathway: Implications for substance use, mood disorders and co-morbidities. | Nunes EJ et al. | β | 2023 | β |
| Maternal adverse childhood experiences (ACEs) and DNA methylation of newborns in cord blood. | Collender P et al. | β | 2023 | β |
| Neuron navigators: A novel frontier with physiological and pathological implications. | Sandeep P et al. | β | 2023 | β |
| Pleiotropic Association of CACNA1C Variants With Neuropsychiatric Disorders. | Wang Z et al. | β | 2023 | β |
| Pleiotropic CACNA1C Variants and Neuronal Function in Psychosis. | Docherty AR | β | 2023 | β |
| Regional expression differences of SERT and TSPAN8 in hippocampus, cerebellum and cortex of wild-type young, adult and middle-aged rats. | YΔ±ldΔ±rΔ±m H et al. | β | 2023 | β |
| Appetitive 50Β kHz calls in a pavlovian conditioned approach task in Cacna1c haploinsufficient rats. | Sangarapillai N et al. | β | 2022 | β |
| A spotter's guide to SNPtic exons: The common splice variants underlying some SNP-phenotype correlations. | Keegan NP et al. | β | 2022 | β |
| Association between CACNA1C gene rs100737 polymorphism and glutamatergic neurometabolites in bipolar disorder. | Scotti-Muzzi E et al. | β | 2022 | β |
| CACNA1C (Ca<sub>V</sub>1.2) and other L-type calcium channels in the pathophysiology and treatment of psychiatric disorders: Advances from functional genomics and pharmacoepidemiology. | Harrison PJ et al. | β | 2022 | β |
| Catalytic Antibodies in Bipolar Disorder: Serum IgGs Hydrolyze Myelin Basic Protein. | Kamaeva DA et al. | β | 2022 | β |
| Chemical Element Profiling in the Sera and Brain of Bipolar Disorders Patients and Healthy Controls. | Sampath VP et al. | β | 2022 | β |
| Extent to which array genotyping and imputation with large reference panels approximate deep whole-genome sequencing. | Hanks SC et al. | β | 2022 | β |
| Genomic and neuroimaging approaches to bipolar disorder. | Oraki Kohshour M et al. | β | 2022 | β |
| Small Molecules as Modulators of Voltage-Gated Calcium Channels in Neurological Disorders: State of the Art and Perspectives. | Lanzetti S et al. | β | 2022 | β |
| The neuroprotective and neuroplastic potential of glutamatergic therapeutic drugs in bipolar disorder. | Guglielmo R et al. | β | 2022 | β |
| Vanadium in Bipolar Disorders-Reviving an Old Hypothesis. | Sampath VP et al. | β | 2022 | β |
| Genetic contributions to bipolar disorder: current status and future directions. | O'Connell KS et al. | β | 2021 | β |
| Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology. | Mullins N et al. | β | 2021 | β |
| Parallel functional testing identifies enhancers active in early postnatal mouse brain. | Lambert JT et al. | β | 2021 | β |
| SERINC2 increases the risk of bipolar disorder in the Chinese population. | Yang D et al. | β | 2021 | β |
| Sleep and Memory Consolidation Dysfunction in Psychiatric Disorders: Evidence for the Involvement of Extracellular Matrix Molecules. | Gisabella B et al. | β | 2021 | β |
| Stick around: Cell-Cell Adhesion Molecules during Neocortical Development. | de AgustΓn-DurΓ‘n D et al. | β | 2021 | β |
| The Role of Genetics in Bipolar Disorder. | Fabbri C | β | 2021 | β |
| A molecular approach to treating cognition in schizophrenia by calcium channel blockade: An open-label pilot study of the calcium-channel antagonist isradipine. | Burdick KE et al. | β | 2020 | β |
| Cacna1c Hemizygosity Results in Aberrant Fear Conditioning to Neutral Stimuli. | Moon AL et al. | β | 2020 | β |
| CACNB2 rs11013860 polymorphism correlates of prefrontal cortex thickness in bipolar patients with first-episode mania. | Chen J et al. | β | 2020 | β |
| Genetic Intersections of Language and Neuropsychiatric Conditions. | Koomar T et al. | β | 2020 | β |
| Genome-wide association study of word reading: Overlap with risk genes for neurodevelopmental disorders. | Price KM et al. | β | 2020 | β |
| Genome-wide study of immune biomarkers in cerebrospinal fluid and serum from patients with bipolar disorder and controls. | Zhang R et al. | β | 2020 | β |
| Neurobiology of bipolar disorders: a review of genetic components, signaling pathways, biochemical changes, and neuroimaging findings. | Scaini G et al. | β | 2020 | β |
| Nimodipine improves cortical efficiency during working memory in healthy subjects. | Zink CF et al. | β | 2020 | β |
| On the diagnostic and neurobiological origins of bipolar disorder. | Charney AW et al. | β | 2020 | β |
| Proof-of-concept study of a multi-gene risk score in adolescent bipolar disorder. | Dimick MK et al. | β | 2020 | β |
| Protein and mRNA expression of protein kinase C (PKC) in the postmortem brain of bipolar and schizophrenic subjects. | Pandey GN et al. | β | 2020 | β |
| Replicated risk <i>CACNA1C</i> variants for major psychiatric disorders may serve as potential therapeutic targets for the shared depressive endophenotype. | Guo X et al. | β | 2020 | β |
| Sex-dependent effects of Cacna1c haploinsufficiency on juvenile social play behavior and pro-social 50-kHz ultrasonic communication in rats. | Kisko TM et al. | β | 2020 | β |
| The use of a gene expression signature and connectivity map to repurpose drugs for bipolar disorder. | Kidnapillai S et al. | β | 2020 | β |
| Transcriptome analysis of neural progenitor cells derived from Lowe syndrome induced pluripotent stem cells: identification of candidate genes for the neurodevelopmental and eye manifestations. | Liu H et al. | β | 2020 | β |
| Aetiology of bipolar disorder: contribution of the L-type voltage-gated calcium channels. | Guo X et al. | β | 2019 | β |
| Association Study of Sequence Variants in Voltage-gated Ca2+ Channel Subunit Alpha-1C and Autism Spectrum Disorders. | Sayad A et al. | β | 2019 | β |
| CACNA1C risk variant affects microstructural connectivity of the amygdala. | Koch K et al. | β | 2019 | β |
| Chitinase-3-like protein 1 levels in bipolar disorder. | Sahin B et al. | β | 2019 | β |
| Compositional epistasis detection using a few prototype disease models. | Cheng L et al. | β | 2019 | β |
| Epigenetics of the molecular clock and bacterial diversity in bipolar disorder. | Bengesser SA et al. | β | 2019 | β |
| GAD1 gene polymorphisms are associated with bipolar I disorder and with blood homovanillic acid levels but not with plasma GABA levels. | ArrΓΊe A et al. | β | 2019 | β |
| Genetic association and functional characterization of MCPH1 gene variation in bipolar disorder and schizophrenia. | Al Eissa MM et al. | β | 2019 | β |
| Genetic loci for alcohol-related life events and substance-induced affective symptoms: indexing the "dark side" of addiction. | Peng Q et al. | β | 2019 | β |
| Genetic Variation in the Psychiatric Risk Gene CACNA1C Modulates Reversal Learning Across Species. | Sykes L et al. | β | 2019 | β |
| Genome-wide association study identifies 30 loci associated with bipolar disorder. | Stahl EA et al. | β | 2019 | β |
| Genomics of Lithium Action and Response. | Pickard BS | β | 2019 | β |
| Glutamate receptor metabotropic 7 (GRM7) gene polymorphisms in mood disorders and attention deficit hyperactive disorder. | Noroozi R et al. | β | 2019 | β |
| GWAS of Behavioral Traits. | Mehta D et al. | β | 2019 | β |
| High Functioning Autism with Missense Mutations in Synaptotagmin-Like Protein 4 (SYTL4) and Transmembrane Protein 187 (TMEM187) Genes: SYTL4- Protein Modeling, Protein-Protein Interaction, Expression Profiling and MicroRNA Studies. | Rafi SK et al. | β | 2019 | β |
| Microglia in post-mortem brain tissue of patients with bipolar disorder are not immune activated. | Sneeboer MAM et al. | β | 2019 | β |
| Rare variant based evidence for oligogenic contribution of neurodevelopmental pathway genes to schizophrenia. | John J et al. | β | 2019 | β |
| Sex and Estrous Cycle Effects on Anxiety- and Depression-Related Phenotypes in a Two-Hit Developmental Stress Model. | Jaric I et al. | β | 2019 | β |
| Two novel genomic regions associated with fearfulness in dogs overlap human neuropsychiatric loci. | Sarviaho R et al. | β | 2019 | β |
| Unravelling the genetic basis of schizophrenia and bipolar disorder with GWAS: A systematic review. | Prata DP et al. | β | 2019 | β |
| An examination of multiple classes of rare variants in extended families with bipolar disorder. | Toma C et al. | β | 2018 | β |
| ATP-activated P2X7 receptor in the pathophysiology of mood disorders and as an emerging target for the development of novel antidepressant therapeutics. | Wei L et al. | β | 2018 | β |
| CACNA1C: Association With Psychiatric Disorders, Behavior, and Neurogenesis. | Moon AL et al. | β | 2018 | β |
| Ca<sup>2+</sup> -Dependent Hyperpolarization Pathways in Sleep Homeostasis and Mental Disorders. | Shi S et al. | β | 2018 | β |
| Combinations of SNP genotypes from the Wellcome Trust Case Control Study of bipolar patients. | Mellerup E et al. | β | 2018 | β |
| Cross-disorder risk gene CACNA1C differentially modulates susceptibility to psychiatric disorders during development and adulthood. | Dedic N et al. | β | 2018 | β |
| De novo UNC13B mutation identified in a bipolar disorder patient increases a rare exon-skipping variant. | Nakamura T et al. | β | 2018 | β |
| Extremely rare variants reveal patterns of germline mutation rate heterogeneity in humans. | Carlson J et al. | β | 2018 | β |
| Gene set enrichment analysis and expression pattern exploration implicate an involvement of neurodevelopmental processes in bipolar disorder. | MΓΌhleisen TW et al. | β | 2018 | β |
| Genetic Variants Involved in Bipolar Disorder, a Rough Road Ahead. | OrrΓΉ G et al. | β | 2018 | β |
| Genome-wide association studies of bipolar disorder: A systematic review of recent findings and their clinical implications. | Ikeda M et al. | β | 2018 | β |
| Outgroup emotion processing in the vACC is modulated by childhood trauma and CACNA1C risk variant. | Krautheim JT et al. | β | 2018 | β |
| Replication of GWAS identified miR-137 and its target gene polymorphisms in Schizophrenia of South Indian population and meta-analysis with Psychiatric Genomics Consortium. | Sudesh R et al. | β | 2018 | β |
| Sex-specific effects of Cacna1c haploinsufficiency on object recognition, spatial memory, and reversal learning capabilities in rats. | Braun MD et al. | β | 2018 | β |
| The Andalusian Bipolar Family (ABiF) Study: Protocol and sample description. | Guzman-Parra J et al. | β | 2018 | β |
| The role of cadherin genes in five major psychiatric disorders: A literature update. | Hawi Z et al. | β | 2018 | β |
| A Genome-Wide Association Study and Complex Network Identify Four Core Hub Genes in Bipolar Disorder. | Xie Z et al. | β | 2017 | β |
| Biological rationale and potential clinical use of gabapentin and pregabalin in bipolar disorder, insomnia and anxiety: protocol for a systematic review and meta-analysis. | Houghton KT et al. | β | 2017 | β |
| Building a genetic risk model for bipolar disorder from genome-wide association data with random forest algorithm. | Chuang LC et al. | β | 2017 | β |
| Can a systems approach produce a better understanding of mood disorders? | Plant N | β | 2017 | β |
| Cognitive Characterization of Schizophrenia Risk Variants Involved in Synaptic Transmission: Evidence of CACNA1C's Role in Working Memory. | Cosgrove D et al. | β | 2017 | β |
| Decreased Nucleus Accumbens Expression of Psychiatric Disorder Risk Gene Cacna1c Promotes Susceptibility to Social Stress. | Terrillion CE et al. | β | 2017 | β |
| Development of multivariable models to predict change in Body Mass Index within a clinical trial population of psychotic individuals. | Harrison RNS et al. | β | 2017 | β |
| Evidence for genetic heterogeneity between clinical subtypes of bipolar disorder. | Charney AW et al. | β | 2017 | β |
| Genetic Risk Score Analysis in Early-Onset Bipolar Disorder. | Croarkin PE et al. | β | 2017 | β |
| Genetic Studies on the Tripartite Glutamate Synapse in the Pathophysiology and Therapeutics of Mood Disorders. | de Sousa RT et al. | β | 2017 | β |
| Genome-wide association analyses of sleep disturbance traits identify new loci and highlight shared genetics with neuropsychiatric and metabolic traits. | Lane JM et al. | β | 2017 | β |
| Genomics of Lithium Action and Response. | Pickard BS | β | 2017 | β |
| Identification of rare nonsynonymous variants in SYNE1/CPG2 in bipolar affective disorder. | Sharp SI et al. | β | 2017 | β |
| Large-scale interaction effects reveal missing heritability in schizophrenia, bipolar disorder and posttraumatic stress disorder. | Woo HJ et al. | β | 2017 | β |
| Metabotropic glutamate receptors as emerging research targets in bipolar disorder. | Blacker CJ et al. | β | 2017 | β |
| Neuroimaging genomics in psychiatry-a translational approach. | Mufford MS et al. | β | 2017 | β |
| Reduced levels of Cacna1c attenuate mesolimbic dopamine system function. | Terrillion CE et al. | β | 2017 | β |
| Role of 108 schizophrenia-associated loci in modulating psychopathological dimensions in schizophrenia and bipolar disorder. | Fabbri C et al. | β | 2017 | β |
| The impact of CACNA1C gene, and its epistasis with ZNF804A, on white matter microstructure in health, schizophrenia and bipolar disorder<sup>1</sup>. | Mallas E et al. | β | 2017 | β |
| The regulation of tetraspanin 8 gene expression-A potential new mechanism in the pathogenesis of bipolar disorder. | Schartner C et al. | β | 2017 | β |
| The relationship between genetic risk variants with brain structure and function in bipolar disorder: A systematic review of genetic-neuroimaging studies. | Pereira LP et al. | β | 2017 | β |
| A novel fuzzy set based multifactor dimensionality reduction method for detecting gene-gene interaction. | Jung HY et al. | β | 2016 | β |
| A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis. | Rivas MA et al. | β | 2016 | β |
| Association of ATP6V1B2 rs1106634 with lifetime risk of depression and hippocampal neurocognitive deficits: possible novel mechanisms in the etiopathology of depression. | Gonda X et al. | β | 2016 | β |
| CACNA1C hypermethylation is associated with bipolar disorder. | Starnawska A et al. | β | 2016 | β |
| CACNA1C risk variant is associated with increased amygdala volume. | Lancaster TM et al. | β | 2016 | β |
| CACNA1C SNP rs1006737 associates with bipolar I disorder independent of the Bcl-2 SNP rs956572 variant and its associated effect on intracellular calcium homeostasis. | Uemura T et al. | β | 2016 | β |
| Deficiency of diacylglycerol kinase Ξ· induces lithium-sensitive mania-like behavior. | Isozaki T et al. | β | 2016 | β |
| Deletion of the Mouse Homolog of <i>CACNA1C</i> Disrupts Discrete Forms of Hippocampal-Dependent Memory and Neurogenesis within the Dentate Gyrus. | Temme SJ et al. | β | 2016 | β |
| Demographic and clinical differences between early- and late-onset bipolar disorders in a multicenter study in China. | Zhang L et al. | β | 2016 | β |
| Diacylglycerol Kinases as Emerging Potential Drug Targets for a Variety of Diseases: An Update. | Sakane F et al. | β | 2016 | β |
| Exome sequencing for bipolar disorder points to roles of de novo loss-of-function and protein-altering mutations. | Kataoka M et al. | β | 2016 | β |
| Genes Involved in Neurodevelopment, Neuroplasticity, and Bipolar Disorder: CACNA1C, CHRNA1, and MAPK1. | CalabrΓ² M et al. | β | 2016 | β |
| Genetic Background Limits Generalizability of Genotype-Phenotype Relationships. | Sittig LJ et al. | β | 2016 | β |
| Genetics of Bipolar Disorder: Recent Update and Future Directions. | Goes FS | β | 2016 | β |
| Genetics of long-term treatment outcome in bipolar disorder. | Fabbri C et al. | β | 2016 | β |
| Genetic variation in the miR-708 gene and its binding targets in bipolar disorder. | Fiorentino A et al. | β | 2016 | β |
| Glutamatergic and HPA-axis pathway genes in bipolar disorder comorbid with alcohol- and substance use disorders. | Dalvie S et al. | β | 2016 | β |
| High-resolution chromosome ideogram representation of recognized genes for bipolar disorder. | Douglas LN et al. | β | 2016 | β |
| Hypomethylation of FAM63B in bipolar disorder patients. | Starnawska A et al. | β | 2016 | β |
| Identification of Susceptible Loci and Enriched Pathways for Bipolar II Disorder Using Genome-Wide Association Studies. | Kao CF et al. | β | 2016 | β |
| Loss of function mutations in ATP2A2 and psychoses: A case report and literature survey. | Nakamura T et al. | β | 2016 | β |
| Mitochondrial Oxidative Phosphorylation System (OXPHOS) Deficits in Schizophrenia: Possible Interactions with Cellular Processes. | Bergman O et al. | β | 2016 | β |
| Monotherapy With Major Antihypertensive Drug Classes and Risk of Hospital Admissions for Mood Disorders. | Boal AH et al. | β | 2016 | β |
| Multi-state outcome analysis of treatments (MOAT): application of a new approach to evaluate outcomes in longitudinal studies of bipolar disorder. | Bowden CL et al. | β | 2016 | β |
| Mutation/SNP analysis in EF-hand calcium binding domain of mitochondrial Ca[Formula: see text] uptake 1 gene in bipolar disorder patients. | Safari R et al. | β | 2016 | β |
| Neurodevelopmental origins of bipolar disorder: iPSC models. | O'Shea KS et al. | β | 2016 | β |
| Overview of the Genetics of Alcohol Use Disorder. | Tawa EA et al. | β | 2016 | β |
| Perseveration by NK1R-/- ('knockout') mice is blunted by doses of methylphenidate that affect neither other aspects of their cognitive performance nor the behaviour of wild-type mice in the 5-Choice Continuous Performance Test. | Pillidge K et al. | β | 2016 | β |
| Primary phospholipase C and brain disorders. | Yang YR et al. | β | 2016 | β |
| Protective coding variants in CFH and PELI3 and a variant near CTRB1 are associated with age-related macular degenerationβ . | Yu Y et al. | β | 2016 | β |
| The Inositol Trisphosphate/Calcium Signaling Pathway in Health and Disease. | Berridge MJ | β | 2016 | β |
| The Neuropsychiatric Disease-Associated Gene cacna1c Mediates Survival of Young Hippocampal Neurons. | Lee AS et al. | β | 2016 | β |
| Trace Amines and the Trace Amine-Associated Receptor 1: Pharmacology, Neurochemistry, and Clinical Implications. | Pei Y et al. | β | 2016 | β |
| Variable Selection with Prior Information for Generalized Linear Models via the Prior LASSO Method. | Jiang Y et al. | β | 2016 | β |
| Abnormal development of monoaminergic neurons is implicated in mood fluctuations and bipolar disorder. | Jukic MM et al. | β | 2015 | β |
| A common risk variant in CACNA1C supports a sex-dependent effect on longitudinal functioning and functional recovery from episodes of schizophrenia-spectrum but not bipolar disorder. | Heilbronner U et al. | β | 2015 | β |
| Ankyrin-G regulates neurogenesis and Wnt signaling by altering the subcellular localization of Ξ²-catenin. | Durak O et al. | β | 2015 | β |
| Assessment of first and second degree relatives of individuals with bipolar disorder shows increased genetic risk scores in both affected relatives and young At-Risk Individuals. | Fullerton JM et al. | β | 2015 | β |
| Association of age-of-onset groups with GWAS significant schizophrenia and bipolar disorder loci in Romanian bipolar I patients. | Grigoroiu-Serbanescu M et al. | β | 2015 | β |
| Association of rare variation in the glutamate receptor gene SLC1A2 with susceptibility to bipolar disorder and schizophrenia. | Fiorentino A et al. | β | 2015 | β |
| Brain Arousal Regulation in Carriers of Bipolar Disorder Risk Alleles. | Jawinski P et al. | β | 2015 | β |
| CACNA1C risk variant affects facial emotion recognition in healthy individuals. | Nieratschker V et al. | β | 2015 | β |
| CACNA1C rs1006737 genotype and bipolar disorder: Focus on intermediate phenotypes and cardiovascular comorbidity. | Ou X et al. | β | 2015 | β |
| Cadherins and catenins in dendrite and synapse morphogenesis. | Seong E et al. | β | 2015 | β |
| Calcium-dependent intracellular signal pathways in primary cultured adipocytes and ANK3 gene variation in patients with bipolar disorder and healthy controls. | Hayashi A et al. | β | 2015 | β |
| Development of a bipolar disorder biobank: differential phenotyping for subsequent biomarker analyses. | Frye MA et al. | β | 2015 | β |
| Emergent treatments based on the pathophysiology of bipolar disorder: A selective review. | Brady RO et al. | β | 2015 | β |
| Genetic analysis of schizophrenia and bipolar disorder reveals polygenicity but also suggests new directions for molecular interrogation. | Neale BM et al. | β | 2015 | β |
| Genome wide association study identifies variants in NBEA associated with migraine in bipolar disorder. | Jacobsen KK et al. | β | 2015 | β |
| Identification of collaborative activities with oxidative phosphorylation in bipolar disorder. | Sawai H et al. | β | 2015 | β |
| Investigating the mechanism(s) underlying switching between states in bipolar disorder. | Young JW et al. | β | 2015 | β |
| Investigation of associations between NR1D1, RORA and RORB genes and bipolar disorder. | Lai YC et al. | β | 2015 | β |
| Major Depressive Disorder and Bipolar Disorder Predispose Youth to Accelerated Atherosclerosis and Early Cardiovascular Disease: A Scientific Statement From the American Heart Association. | Goldstein BI et al. | β | 2015 | β |
| MicroRNAs: Small molecules with big roles in neurodevelopment and diseases. | Sun E et al. | β | 2015 | β |
| Polygenic risk scores in imaging genetics: Usefulness and applications. | Dima D et al. | β | 2015 | β |
| Premorbid obesity and metabolic disturbances as promising clinical targets for the prevention and early screening of bipolar disorder. | GΓ‘lvez JF et al. | β | 2015 | β |
| Prevalence of Huntington's disease gene CAG trinucleotide repeat alleles in patients with bipolar disorder. | Ramos EM et al. | β | 2015 | β |
| Schizophrenia and Depression Co-Morbidity: What We have Learned from Animal Models. | Samsom JN et al. | β | 2015 | β |
| Schizophrenia Related Variants in CACNA1C also Confer Risk of Autism. | Li J et al. | β | 2015 | β |
| Seasonality shows evidence for polygenic architecture and genetic correlation with schizophrenia and bipolar disorder. | Byrne EM et al. | β | 2015 | β |
| The bipolar depression electrical treatment trial (BETTER): design, rationale, and objectives of a randomized, sham-controlled trial and data from the pilot study phase. | Pereira Junior Bde S et al. | β | 2015 | β |
| The effects of the CACNA1C rs1006737 A/G on affective startle modulation in healthy males. | Pasparakis E et al. | β | 2015 | β |
| A genome-wide association analysis of a broad psychosis phenotype identifies three loci for further investigation. | Psychosis Endophenotypes International Consortium et al. | β | 2014 | β |
| A genome-wide linkage scan of bipolar disorder in Latino families identifies susceptibility loci at 8q24 and 14q32. | Gonzalez S et al. | β | 2014 | β |
| A genome-wide supported variant in CACNA1C influences hippocampal activation during episodic memory encoding and retrieval. | Krug A et al. | β | 2014 | β |
| Allelic association, DNA resequencing and copy number variation at the metabotropic glutamate receptor GRM7 gene locus in bipolar disorder. | Kandaswamy R et al. | β | 2014 | β |
| Analysis of ANK3 and CACNA1C variants identified in bipolar disorder whole genome sequence data. | Fiorentino A et al. | β | 2014 | β |
| A role for noncoding variation in schizophrenia. | Roussos P et al. | β | 2014 | β |
| Association between circadian genes, bipolar disorders and chronotypes. | Etain B et al. | β | 2014 | β |
| Association of rs1006737 in CACNA1C with alterations in prefrontal activation and fronto-hippocampal connectivity. | Paulus FM et al. | β | 2014 | β |
| CACNA1C genotype explains interindividual differences in amygdala volume among patients with schizophrenia. | Wolf C et al. | β | 2014 | β |
| CACNA1C, schizophrenia and major depressive disorder in the Han Chinese population. | He K et al. | β | 2014 | β |
| Calcium signalling and psychiatric disease: bipolar disorder and schizophrenia. | Berridge MJ | β | 2014 | β |
| Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles. | Goldstein JI et al. | β | 2014 | β |
| Common variants in the CDH7 gene are associated with major depressive disorder in the Han Chinese population. | Li X et al. | β | 2014 | β |
| Diacylglycerol kinase as a possible therapeutic target for neuronal diseases. | Shirai Y et al. | β | 2014 | β |
| DNA methylation profiling in the thalamus and hippocampus of postnatal malnourished mice, including effects related to long-term potentiation. | Weng X et al. | β | 2014 | β |
| Exploring the associations between genetic variants in genes encoding for subunits of calcium channel and subtypes of bipolar disorder. | Jan WC et al. | β | 2014 | β |
| Frontotemporal White Matter in Adolescents with, and at-Risk for, Bipolar Disorder. | de Zwarte SM et al. | β | 2014 | β |
| Genes in the serotonin pathway are associated with bipolar affective disorder in a Han Chinese population. | Xiang B et al. | β | 2014 | β |
| Genetic association of the tachykinin receptor 1 TACR1 gene in bipolar disorder, attention deficit hyperactivity disorder, and the alcohol dependence syndrome. | Sharp SI et al. | β | 2014 | β |
| Genetic modulation of the response bias towards facial displays of anger and happiness. | Gohier B et al. | β | 2014 | β |
| Genetics of bipolar disorder. | Kerner B | β | 2014 | β |
| Genetic variation in CACNA1C affects neural processing in major depression. | Backes H et al. | β | 2014 | β |
| Genome-wide analysis of single nucleotide polymorphisms and copy number variants in fibromyalgia suggest a role for the central nervous system. | Docampo E et al. | β | 2014 | β |
| Genome-wide association study of bipolar disorder in Canadian and UK populations corroborates disease loci including SYNE1 and CSMD1. | Xu W et al. | β | 2014 | β |
| Genome-wide association study of opioid dependence: multiple associations mapped to calcium and potassium pathways. | Gelernter J et al. | β | 2014 | β |
| Genomic view of bipolar disorder revealed by whole genome sequencing in a genetic isolate. | Georgi B et al. | β | 2014 | β |
| Glia and immune cell signaling in bipolar disorder: insights from neuropharmacology and molecular imaging to clinical application. | Watkins CC et al. | β | 2014 | β |
| Hippocampal and frontolimbic function as intermediate phenotype for psychosis: evidence from healthy relatives and a common risk variant in CACNA1C. | Erk S et al. | β | 2014 | β |
| Identification of gene ontologies linked to prefrontal-hippocampal functional coupling in the human brain. | Dixson L et al. | β | 2014 | β |
| Identification of novel loci for bipolar I disorder in a multi-stage genome-wide association study. | Kuo PH et al. | β | 2014 | β |
| Identification of pathways for bipolar disorder: a meta-analysis. | Nurnberger JI et al. | β | 2014 | β |
| Imaging genetics in obsessive-compulsive disorder: linking genetic variations to alterations in neuroimaging. | GrΓΌnblatt E et al. | β | 2014 | β |
| Inference of SNP-gene regulatory networks by integrating gene expressions and genetic perturbations. | Kim DC et al. | β | 2014 | β |
| Intercellular protein-protein interactions at synapses. | Yang X et al. | β | 2014 | β |
| Meta-analysis demonstrates lack of association of the GSK3B -50C/T polymorphism with risk of bipolar disorder. | Chen G et al. | β | 2014 | β |
| MIR137 gene and target gene CACNA1C of miR-137 contribute to schizophrenia susceptibility in Han Chinese. | Guan F et al. | β | 2014 | β |
| Multisystem component phenotypes of bipolar disorder for genetic investigations of extended pedigrees. | Fears SC et al. | β | 2014 | β |
| Multivariate analysis reveals genetic associations of the resting default mode network in psychotic bipolar disorder and schizophrenia. | Meda SA et al. | β | 2014 | β |
| New developments in the genetics of bipolar disorder. | Shinozaki G et al. | β | 2014 | β |
| Non-synonymous single nucleotide polymorphisms in the P2X receptor genes: association with diseases, impact on receptor functions and potential use as diagnosis biomarkers. | Caseley EA et al. | β | 2014 | β |
| Replication of brain function effects of a genome-wide supported psychiatric risk variant in the CACNA1C gene and new multi-locus effects. | Erk S et al. | β | 2014 | β |
| Replication of previous genome-wide association studies of psychiatric diseases in a large schizophrenia case-control sample from Spain. | Ivorra JL et al. | β | 2014 | β |
| Research review: Polygenic methods and their application to psychiatric traits. | Wray NR et al. | β | 2014 | β |
| Risk and information evaluation of prioritized genes for complex traits: application to bipolar disorder. | Kao CF et al. | β | 2014 | β |
| The impact of a CACNA1C gene polymorphism on learning and hippocampal formation in healthy individuals: a diffusion tensor imaging study. | Dietsche B et al. | β | 2014 | β |
| The neurobiology of bipolar disorder: identifying targets for specific agents and synergies for combination treatment. | Andreazza AC et al. | β | 2014 | β |
| The role of L-type voltage-gated calcium channels Cav1.2 and Cav1.3 in normal and pathological brain function. | Berger SM et al. | β | 2014 | β |
| A bivariate mann-whitney approach for unraveling genetic variants and interactions contributing to comorbidity. | Wen Y et al. | β | 2013 | β |
| A genome-wide association study of seasonal pattern mania identifies NF1A as a possible susceptibility gene for bipolar disorder. | Lee HJ et al. | β | 2013 | β |
| A multiclass likelihood ratio approach for genetic risk prediction allowing for phenotypic heterogeneity. | Wen Y et al. | β | 2013 | β |
| Anxiety and affective disorder comorbidity related to serotonin and other neurotransmitter systems: obsessive-compulsive disorder as an example of overlapping clinical and genetic heterogeneity. | Murphy DL et al. | β | 2013 | β |
| A review of potassium channels in bipolar disorder. | Judy JT et al. | β | 2013 | β |
| Association of genetic variation in CACNA1C with bipolar disorder in Han Chinese. | Zhang X et al. | β | 2013 | β |
| Biomarkers in bipolar disorder: a positional paper from the International Society for Bipolar Disorders Biomarkers Task Force. | Frey BN et al. | β | 2013 | β |
| CACNA1C risk variant and amygdala activity in bipolar disorder, schizophrenia and healthy controls. | Tesli M et al. | β | 2013 | β |
| Channelopathy pathogenesis in autism spectrum disorders. | Schmunk G et al. | β | 2013 | β |
| Convergent functional genomics of psychiatric disorders. | Niculescu AB | β | 2013 | β |
| Dopaminergic gene polymorphisms and cognitive function in a north Indian schizophrenia cohort. | Kukshal P et al. | β | 2013 | β |
| Evidence for single nucleotide polymorphisms and their association with bipolar disorder. | Szczepankiewicz A | β | 2013 | β |
| Functions of class V myosins in neurons. | Hammer JA et al. | β | 2013 | β |
| Genetic and neurocognitive foundations of emotion abnormalities in bipolar disorder. | Van Rheenen TE et al. | β | 2013 | β |
| Genetic predictors of risk and resilience in psychiatric disorders: a cross-disorder genome-wide association study of functional impairment in major depressive disorder, bipolar disorder, and schizophrenia. | McGrath LM et al. | β | 2013 | β |
| Genetics of bipolar disorder. | Craddock N et al. | β | 2013 | β |
| Genetic variants on 3q21 and in the Sp8 transcription factor gene (SP8) as susceptibility loci for psychotic disorders: a genetic association study. | Kondo K et al. | β | 2013 | β |
| Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder. | Chen DT et al. | β | 2013 | β |
| Genotyping of single nucleotide polymorphisms by melting curve analysis using thin film semi-transparent heaters integrated in a lab-on-foil system. | Ohlander A et al. | β | 2013 | β |
| Glycogen synthase kinase 3Ξ² gene polymorphisms may be associated with bipolar I disorder and the therapeutic response to lithium. | Lin YF et al. | β | 2013 | β |
| Heritability and genome-wide SNP linkage analysis of temperament in bipolar disorder. | Greenwood TA et al. | β | 2013 | β |
| Heritability and linkage analysis of personality in bipolar disorder. | Greenwood TA et al. | β | 2013 | β |
| High insulin-like growth factor-1 in patients with bipolar I disorder: a trait marker? | Kim YK et al. | β | 2013 | β |
| Hypomania spectrum disorders from adolescence to adulthood: a 15-year follow-up of a community sample. | PÀÀren A et al. | β | 2013 | β |
| Lithium's role in neural plasticity and its implications for mood disorders. | Gray JD et al. | β | 2013 | β |
| Major channels involved in neuropsychiatric disorders and therapeutic perspectives. | Imbrici P et al. | β | 2013 | β |
| Mitochondrial modulators for bipolar disorder: a pathophysiologically informed paradigm for new drug development. | Nierenberg AA et al. | β | 2013 | β |
| Myosin motors at neuronal synapses: drivers of membrane transport and actin dynamics. | Kneussel M et al. | β | 2013 | β |
| Myosin Vb gene is associated with schizophrenia in Chinese Han population. | Chen Y et al. | β | 2013 | β |
| Neuropsychological deficits in mice depleted of the schizophrenia susceptibility gene CSMD1. | Steen VM et al. | β | 2013 | β |
| No evidence for association between bipolar disorder risk gene variants and brain structural phenotypes. | Tesli M et al. | β | 2013 | β |
| Overlapping and distinct gray and white matter abnormalities in schizophrenia and bipolar I disorder. | Anderson D et al. | β | 2013 | β |
| Pathway analysis using information from allele-specific gene methylation in genome-wide association studies for bipolar disorder. | Chuang LC et al. | β | 2013 | β |
| Polygenic risk and white matter integrity in individuals at high risk of mood disorder. | Whalley HC et al. | β | 2013 | β |
| Prefrontal cortical dysfunction after overexpression of histone deacetylase 1. | Jakovcevski M et al. | β | 2013 | β |
| Proteomic analysis of lymphoblastoid cells derived from monozygotic twins discordant for bipolar disorder: a preliminary study. | Kazuno AA et al. | β | 2013 | β |
| Rare variants in CFI, C3 and C9 are associated with high risk of advanced age-related macular degeneration. | Seddon JM et al. | β | 2013 | β |
| Replication of Genome-Wide Association Studies (GWAS) loci for sleep in the British G1219 cohort. | Parsons MJ et al. | β | 2013 | β |
| Selected rapporteur summaries from the XX World Congress of Psychiatric Genetics, Hamburg, Germany, October 14-18, 2012. | Anderson-Schmidt H et al. | β | 2013 | β |
| Sub-optimal parenting is associated with schizotypic and anxiety personality traits in adulthood. | Giakoumaki SG et al. | β | 2013 | β |
| Suggestive evidence for association between L-type voltage-gated calcium channel (CACNA1C) gene haplotypes and bipolar disorder in Latinos: a family-based association study. | Gonzalez S et al. | β | 2013 | β |
| The CACNA1C risk allele selectively impacts on executive function in bipolar type I disorder. | Soeiro-de-Souza MG et al. | β | 2013 | β |
| The human L-type calcium channel Cav1.3 regulates insulin release and polymorphisms in CACNA1D associate with type 2 diabetes. | Reinbothe TM et al. | β | 2013 | β |
| The impact of CACNA1C allelic variation on effective connectivity during emotional processing in bipolar disorder. | Radua J et al. | β | 2013 | β |
| The impact of phenotypic and genetic heterogeneity on results of genome wide association studies of complex diseases. | Manchia M et al. | β | 2013 | β |
| The psychiatric vulnerability gene CACNA1C and its sex-specific relationship with personality traits, resilience factors and depressive symptoms in the general population. | Strohmaier J et al. | β | 2013 | β |
| Validation of schizophrenia-associated genes CSMD1, C10orf26, CACNA1C and TCF4 as miR-137 targets. | Kwon E et al. | β | 2013 | β |
| White matter integrity as an intermediate phenotype: exploratory genome-wide association analysis in individuals at high risk of bipolar disorder. | Sprooten E et al. | β | 2013 | β |
| ANK3 and CACNA1C--missing genetic link for bipolar disorder and major depressive disorder in two German case-control samples. | Kloiber S et al. | β | 2012 | β |
| Association between SNPs and gene expression in multiple regions of the human brain. | Kim S et al. | β | 2012 | β |
| Behavioral genetics of affective and anxiety disorders. | Domschke K et al. | β | 2012 | β |
| CACNA1C (Cav1.2) in the pathophysiology of psychiatric disease. | Bhat S et al. | β | 2012 | β |
| Cadherins and neuropsychiatric disorders. | Redies C et al. | β | 2012 | β |
| Cardiometabolic Health in Bipolar Disorder. | Kemp DE et al. | β | 2012 | β |
| Common genetic variants and gene-expression changes associated with bipolar disorder are over-represented in brain signaling pathway genes. | Pedroso I et al. | β | 2012 | β |
| Data mining approaches for genome-wide association of mood disorders. | Pirooznia M et al. | β | 2012 | β |
| Developmental regulation of expression of schizophrenia susceptibility genes in the primate hippocampal formation. | Favre G et al. | β | 2012 | β |
| Disease liability prediction from large scale genotyping data using classifiers with a reject option. | Quevedo JR et al. | β | 2012 | β |
| Effect of variation in diacylglycerol kinase Ξ· (DGKH) gene on brain function in a cohort at familial risk of bipolar disorder. | Whalley HC et al. | β | 2012 | β |
| Effects of the CACNA1C risk allele on neurocognition in patients with schizophrenia and healthy individuals. | Hori H et al. | β | 2012 | β |
| Electroconvulsive stimulations prevent chronic stress-induced increases in L-type calcium channel mRNAs in the hippocampus and basolateral amygdala. | Maigaard K et al. | β | 2012 | β |
| Expression profiling in neuropsychiatric disorders: emphasis on glutamate receptors in bipolar disorder. | Ginsberg SD et al. | β | 2012 | β |
| Genetic architectures of psychiatric disorders: the emerging picture and its implications. | Sullivan PF et al. | β | 2012 | β |
| Genetic association of cyclic AMP signaling genes with bipolar disorder. | McDonald ML et al. | β | 2012 | β |
| Genetic heterogeneity according to age at onset in bipolar disorder: a combined positional cloning and candidate gene approach. | Dizier MH et al. | β | 2012 | β |
| Genetic overlap of schizophrenia and bipolar disorder in a high-density linkage survey in the Portuguese Island population. | Fanous AH et al. | β | 2012 | β |
| Genome wide association studies (GWAS) and copy number variation (CNV) studies of the major psychoses: what have we learnt? | Lee KW et al. | β | 2012 | β |
| Genome-wide association study of major depressive disorder: new results, meta-analysis, and lessons learned. | Wray NR et al. | β | 2012 | β |
| Genome-wide linkage analysis of 972 bipolar pedigrees using single-nucleotide polymorphisms. | Badner JA et al. | β | 2012 | β |
| Genome-wide survey implicates the influence of copy number variants (CNVs) in the development of early-onset bipolar disorder. | Priebe L et al. | β | 2012 | β |
| Identification of a CACNA2D4 deletion in late onset bipolar disorder patients and implications for the involvement of voltage-dependent calcium channels in psychiatric disorders. | Van Den Bossche MJ et al. | β | 2012 | β |
| Incorporating Information of microRNAs into Pathway Analysis in a Genome-Wide Association Study of Bipolar Disorder. | Shih WL et al. | β | 2012 | β |
| Influence of an interaction between lithium salts and a functional polymorphism in SLC1A2 on the history of illness in bipolar disorder. | Dallaspezia S et al. | β | 2012 | β |
| Ion channels and schizophrenia: a gene set-based analytic approach to GWAS data for biological hypothesis testing. | Askland K et al. | β | 2012 | β |
| Methods for meta-analyses of genome-wide association studies: critical assessment of empirical evidence. | GΓΆgele M et al. | β | 2012 | β |
| Potential opposite roles of the extracellular signal-regulated kinase (ERK) pathway in autism spectrum and bipolar disorders. | Kalkman HO | β | 2012 | β |
| Recent progress on type II diacylglycerol kinases: the physiological functions of diacylglycerol kinase Ξ΄, Ξ· and ΞΊ and their involvement in disease. | Sakai H et al. | β | 2012 | β |
| Reduced anxiety and depression-like behaviours in the circadian period mutant mouse afterhours. | Keers R et al. | β | 2012 | β |
| Re-sequencing of ankyrin 3 exon 48 and case-control association analysis of rare variants in bipolar disorder type I. | Doyle GA et al. | β | 2012 | β |
| Sequencing of the ANKYRIN 3 gene (ANK3) encoding ankyrin G in bipolar disorder reveals a non-conservative amino acid change in a short isoform of ankyrin G. | Dedman A et al. | β | 2012 | β |
| Support for calcium channel gene defects in autism spectrum disorders. | Lu AT et al. | β | 2012 | β |
| Tests of linkage and allelic association between markers in the 1p36 PRKCZ (protein kinase C zeta) gene region and bipolar affective disorder. | Kandaswamy R et al. | β | 2012 | β |
| The Association between COMT, BDNF, and NRG1 and Premorbid Social Functioning in Patients with Psychosis, Their Relatives, and Controls. | Walshe M et al. | β | 2012 | β |
| The effects of CACNA1C gene polymorphism on spatial working memory in both healthy controls and patients with schizophrenia or bipolar disorder. | Zhang Q et al. | β | 2012 | β |
| The impact of the CACNA1C risk allele on limbic structures and facial emotions recognition in bipolar disorder subjects and healthy controls. | Soeiro-de-Souza MG et al. | β | 2012 | β |
| Ultrafast genome-wide scan for SNP-SNP interactions in common complex disease. | Prabhu S et al. | β | 2012 | β |
| Affective symptoms are associated with markers of inflammation and immune activation in bipolar disorders but not in schizophrenia. | Hope S et al. | β | 2011 | β |
| Analysis of genetic deletions and duplications in the University College London bipolar disorder case control sample. | McQuillin A et al. | β | 2011 | β |
| Association analysis of ANK3 gene variants in nordic bipolar disorder and schizophrenia case-control samples. | Tesli M et al. | β | 2011 | β |
| Bipolar disorder risk alleles in adult ADHD patients. | Landaas ET et al. | β | 2011 | β |
| Case-case genome-wide association analysis shows markers differentially associated with schizophrenia and bipolar disorder and implicates calcium channel genes. | Curtis D et al. | β | 2011 | β |
| Clustered coding variants in the glutamate receptor complexes of individuals with schizophrenia and bipolar disorder. | Frank RA et al. | β | 2011 | β |
| Combinations of SNPs related to signal transduction in bipolar disorder. | Koefoed P et al. | β | 2011 | β |
| Common sequence variants in the major histocompatibility complex region associate with cerebral ventricular size in schizophrenia. | Agartz I et al. | β | 2011 | β |
| Comparative linkage meta-analysis reveals regionally-distinct, disparate genetic architectures: application to bipolar disorder and schizophrenia. | Tang B et al. | β | 2011 | β |
| Confirmation of prior evidence of genetic susceptibility to alcoholism in a genome-wide association study of comorbid alcoholism and bipolar disorder. | Lydall GJ et al. | β | 2011 | β |
| Cross-disorder analysis of bipolar risk genes: further evidence of DGKH as a risk gene for bipolar disorder, but also unipolar depression and adult ADHD. | Weber H et al. | β | 2011 | β |
| Database of genetic studies of bipolar disorder. | Piletz JE et al. | β | 2011 | β |
| Do COMT, BDNF and NRG1 polymorphisms influence P50 sensory gating in psychosis? | Shaikh M et al. | β | 2011 | β |
| Effects of a CACNA1C genotype on attention networks in healthy individuals. | Thimm M et al. | β | 2011 | β |
| Efficient replication of over 180 genetic associations with self-reported medical data. | Tung JY et al. | β | 2011 | β |
| Evidence of associations between bipolar disorder and the brain-derived neurotrophic factor (BDNF) gene. | Sears C et al. | β | 2011 | β |
| Fine mapping of candidate regions for bipolar disorder provides strong evidence for susceptibility loci on chromosomes 7q. | Xu H et al. | β | 2011 | β |
| Gene expression and genetic variation data implicate PCLO in bipolar disorder. | Choi KH et al. | β | 2011 | β |
| Genetic association and sequencing of the insulin-like growth factor 1 gene in bipolar affective disorder. | Pereira AC et al. | β | 2011 | β |
| Genetic association of bipolar disorder with the Ξ²(3) nicotinic receptor subunit gene. | Hartz SM et al. | β | 2011 | β |
| Genetics of bipolar disorder. | Wendland JR et al. | β | 2011 | β |
| Genetics of schizophrenia: new findings and challenges. | Gejman PV et al. | β | 2011 | β |
| Genome-wide association analysis of age at onset and psychotic symptoms in bipolar disorder. | Belmonte Mahon P et al. | β | 2011 | β |
| Genome-wide association scan of korean autism spectrum disorders with language delay: a preliminary study. | Cho SC et al. | β | 2011 | β |
| Genome-wide association study identifies a susceptibility locus for schizophrenia in Han Chinese at 11p11.2. | Yue WH et al. | β | 2011 | β |
| Genome-wide association study identifies genetic variation in neurocan as a susceptibility factor for bipolar disorder. | Cichon S et al. | β | 2011 | β |
| Genome-wide association study in bipolar patients stratified by co-morbidity. | Kerner B et al. | β | 2011 | β |
| Genome-wide association study in German patients with attention deficit/hyperactivity disorder. | Hinney A et al. | β | 2011 | β |
| Genome-wide association study of bipolar I disorder in the Han Chinese population. | Lee MT et al. | β | 2011 | β |
| Genome-wide association study of personality traits in bipolar patients. | Alliey-Rodriguez N et al. | β | 2011 | β |
| Genome-wide association study on bipolar disorder in the Bulgarian population. | Yosifova A et al. | β | 2011 | β |
| Genome-wide interaction-based association analysis identified multiple new susceptibility Loci for common diseases. | Liu Y et al. | β | 2011 | β |
| Genome-wide searches for bipolar disorder genes. | Alsabban S et al. | β | 2011 | β |
| Human microRNAs miR-22, miR-138-2, miR-148a, and miR-488 are associated with panic disorder and regulate several anxiety candidate genes and related pathways. | MuiΓ±os-Gimeno M et al. | β | 2011 | β |
| Increased de novo copy number variants in the offspring of older males. | Flatscher-Bader T et al. | β | 2011 | β |
| Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4. | Psychiatric GWAS Consortium Bipolar Disorder Working Group | β | 2011 | β |
| Meta-analysis of heterogeneous data sources for genome-scale identification of risk genes in complex phenotypes. | Pers TH et al. | β | 2011 | β |
| Modifiers and subtype-specific analyses in whole-genome association studies: a likelihood framework. | Lee PH et al. | β | 2011 | β |
| No association between bipolar disorder risk polymorphisms in ANK3 and CACNA1C and common migraine. | WΓΆber-BingΓΆl C et al. | β | 2011 | β |
| Nominal association between a polymorphism in DGKH and bipolar disorder detected in a meta-analysis of East Asian case-control samples. | Takata A et al. | β | 2011 | β |
| Novel loci for major depression identified by genome-wide association study of Sequenced Treatment Alternatives to Relieve Depression and meta-analysis of three studies. | Shyn SI et al. | β | 2011 | β |
| Polygenic dissection of the bipolar phenotype. | Hamshere ML et al. | β | 2011 | β |
| Replication of association of 3p21.1 with susceptibility to bipolar disorder but not major depression. | Breen G et al. | β | 2011 | β |
| Response to treatment in bipolar disorder. | Cruceanu C et al. | β | 2011 | β |
| Signal transduction pathways in the pathophysiology of bipolar disorder. | Gawryluk JW et al. | β | 2011 | β |
| The association of genetic variation in CACNA1C with structure and function of a frontotemporal system. | Wang F et al. | β | 2011 | β |
| The CACNA1C and ANK3 risk alleles impact on affective personality traits and startle reactivity but not on cognition or gating in healthy males. | Roussos P et al. | β | 2011 | β |
| The cognitive impact of the ANK3 risk variant for bipolar disorder: initial evidence of selectivity to signal detection during sustained attention. | Ruberto G et al. | β | 2011 | β |
| The complement control-related genes CSMD1 and CSMD2 associate to schizophrenia. | HΓ₯vik B et al. | β | 2011 | β |
| Using linkage information to weight a genome-wide association of bipolar disorder. | Howrigan DP et al. | β | 2011 | β |
| Advances in molecular genetics of panic disorder. | Maron E et al. | β | 2010 | β |
| A genome-wide association study of bipolar disorder and comorbid migraine. | Oedegaard KJ et al. | β | 2010 | β |
| A genome-wide association study of bipolar disorder in Norwegian individuals, followed by replication in Icelandic sample. | Djurovic S et al. | β | 2010 | β |
| A genome-wide linkage study of bipolar disorder and co-morbid migraine: replication of migraine linkage on chromosome 4q24, and suggestion of an overlapping susceptibility region for both disorders on chromosome 20p11. | Oedegaard KJ et al. | β | 2010 | β |
| Allele specific analysis of the ADRBK2 gene in lymphoblastoid cells from bipolar disorder patients. | McCarthy MJ et al. | β | 2010 | β |
| An approach based on a genome-wide association study reveals candidate loci for narcolepsy. | Shimada M et al. | β | 2010 | β |
| An investigation of candidate regions for association with bipolar disorder. | Knight J et al. | β | 2010 | β |
| Association analyses between brain-expressed fatty-acid binding protein (FABP) genes and schizophrenia and bipolar disorder. | Iwayama Y et al. | β | 2010 | β |
| Association analysis between polymorphisms in the myo-inositol monophosphatase 2 (IMPA2) gene and bipolar disorder. | Bloch PJ et al. | β | 2010 | β |
| Association analysis of PALB2 and BRCA2 in bipolar disorder and schizophrenia in a scandinavian case-control sample. | Tesli M et al. | β | 2010 | β |
| Association between polymorphisms in the metallophosphoesterase (MPPE1) gene and bipolar disorder. | Lohoff FW et al. | β | 2010 | β |
| A systematic association mapping on chromosome 6q in bipolar affective disorder--evidence for the melanin-concentrating-hormone-receptor-2 gene as a risk factor for bipolar affective disorder. | Abou Jamra R et al. | β | 2010 | β |
| Bipolar and ADHD Comorbidity: Both Artifact and Outgrowth of Shared Mechanisms. | Youngstrom EA et al. | β | 2010 | β |
| [Bipolar depression. Epidemiology, etiopathogenesis, and course]. | Haack S et al. | β | 2010 | β |
| CACNA1C (rs1006737) is associated with schizophrenia. | Nyegaard M et al. | β | 2010 | β |
| Catechol-O-methyltransferase Val158Met polymorphism affects therapeutic response to mood stabilizer in symptomatic manic patients. | Lee HY et al. | β | 2010 | β |
| CaV1.2 channelopathies: from arrhythmias to autism, bipolar disorder, and immunodeficiency. | Liao P et al. | β | 2010 | β |
| Circadian rhythms and sleep in bipolar disorder. | Murray G et al. | β | 2010 | β |
| Coming to grips with complex disorders: genetic risk prediction in bipolar disorder using panels of genes identified through convergent functional genomics. | Patel SD et al. | β | 2010 | β |
| Cross-disorder genomewide analysis of schizophrenia, bipolar disorder, and depression. | Huang J et al. | β | 2010 | β |
| Differential association of circadian genes with mood disorders: CRY1 and NPAS2 are associated with unipolar major depression and CLOCK and VIP with bipolar disorder. | Soria V et al. | β | 2010 | β |
| Effect of CACNA1C rs1006737 on neural correlates of verbal fluency in healthy individuals. | Krug A et al. | β | 2010 | β |
| European collaborative study of early-onset bipolar disorder: Evidence for genetic heterogeneity on 2q14 according to age at onset. | Mathieu F et al. | β | 2010 | β |
| Family-based association analysis to finemap bipolar linkage peak on chromosome 8q24 using 2,500 genotyped SNPs and 15,000 imputed SNPs. | Zhang P et al. | β | 2010 | β |
| Family-based association study for bipolar affective disorder. | Secolin R et al. | β | 2010 | β |
| Fine mapping of the 9q31 Hirschsprung's disease locus. | Tang CS et al. | β | 2010 | β |
| Functional variants of TSPAN8 are associated with bipolar disorder and schizophrenia. | Scholz CJ et al. | β | 2010 | β |
| Genetic research into bipolar disorder: the need for a research framework that integrates sophisticated molecular biology and clinically informed phenotype characterization. | Schulze TG | β | 2010 | β |
| Genetic variation in CACNA1C affects brain circuitries related to mental illness. | Bigos KL et al. | β | 2010 | β |
| Genome-wide approaches to schizophrenia. | Duan J et al. | β | 2010 | β |
| Genome wide association for addiction: replicated results and comparisons of two analytic approaches. | Drgon T et al. | β | 2010 | β |
| Genome-wide association scan for five major dimensions of personality. | Terracciano A et al. | β | 2010 | β |
| Genome-wide association studies: a powerful tool for neurogenomics. | Cowperthwaite MC et al. | β | 2010 | β |
| Genome-wide association study of recurrent major depressive disorder in two European case-control cohorts. | Muglia P et al. | β | 2010 | β |
| Genome-wide linkage scan of bipolar disorder in a Colombian population isolate replicates Loci on chromosomes 7p21-22, 1p31, 16p12 and 21q21-22 and identifies a novel locus on chromosome 12q. | Kremeyer B et al. | β | 2010 | β |
| Genome-wide linkage using the Social Responsiveness Scale in Utah autism pedigrees. | Coon H et al. | β | 2010 | β |
| Human behavioral informatics in genetic studies of neuropsychiatric disease: multivariate profile-based analysis. | Bloss CS et al. | β | 2010 | β |
| Imaging genetics--days of future past. | Bigos KL et al. | β | 2010 | β |
| Increased peripheral blood expression of electron transport chain genes in bipolar depression. | Beech RD et al. | β | 2010 | β |
| Letter to the editor: Further evidence is required to confirm association between CACNA1C gene variants and bipolar affective disorder. | Nyholt DR | β | 2010 | β |
| Linkage disequilibrium mapping of the chromosome 6q21-22.31 bipolar I disorder susceptibility locus. | Fan J et al. | β | 2010 | β |
| L-type calcium channels and psychiatric disorders: A brief review. | Casamassima F et al. | β | 2010 | β |
| Meta-analysis of genome-wide association data identifies a risk locus for major mood disorders on 3p21.1. | McMahon FJ et al. | β | 2010 | β |
| Methods: genetic epidemiology. | Benke KS et al. | β | 2010 | β |
| MicroRNA expression profiling in the prefrontal cortex of individuals affected with schizophrenia and bipolar disorders. | Kim AH et al. | β | 2010 | β |
| Molecular genetics of attention-deficit/hyperactivity disorder: an overview. | Banaschewski T et al. | β | 2010 | β |
| Mood disorder susceptibility gene CACNA1C modifies mood-related behaviors in mice and interacts with sex to influence behavior in mice and diagnosis in humans. | Dao DT et al. | β | 2010 | β |
| New findings in the genetics of major psychoses. | NΓΆthen MM et al. | β | 2010 | β |
| NK1 (TACR1) receptor gene 'knockout' mouse phenotype predicts genetic association with ADHD. | Yan TC et al. | β | 2010 | β |
| Pharmacogenetics of lithium response in bipolar disorder. | McCarthy MJ et al. | β | 2010 | β |
| Pharmacogenomics of mood stabilizers in the treatment of bipolar disorder. | Squassina A et al. | β | 2010 | β |
| Phenotypic effects of a bipolar liability gene among individuals with major depressive disorder. | Casamassima F et al. | β | 2010 | β |
| Psychiatric syndromes in individuals with chromosome 18 abnormalities. | Zavala J et al. | β | 2010 | β |
| Rare copy number variants: a point of rarity in genetic risk for bipolar disorder and schizophrenia. | Grozeva D et al. | β | 2010 | β |
| Replication of GWAS of bipolar disorder: association of SNPs near CDH7 with bipolar disorder and visual processing. | Soronen P et al. | β | 2010 | β |
| Resequencing and association analysis of arylalkylamine N-acetyltransferase (AANAT) gene and its contribution to major depression susceptibility. | Soria V et al. | β | 2010 | β |
| Selected summaries from the XVII World Congress of Psychiatric Genetics, San Diego, California, USA, 4-8 November 2009. | Amstadter AB et al. | β | 2010 | β |
| Serotonin 6 receptor gene and mood disorders: case-control study and meta-analysis. | Fukuo Y et al. | β | 2010 | β |
| Suggestive linkage of the child behavior checklist juvenile bipolar disorder phenotype to 1p21, 6p21, and 8q21. | Doyle AE et al. | β | 2010 | β |
| Support for a bipolar affective disorder susceptibility locus on chromosome 12q24.3. | ButtenschΓΈn HN et al. | β | 2010 | β |
| Support of association between BRD1 and both schizophrenia and bipolar affective disorder. | Nyegaard M et al. | β | 2010 | β |
| The bipolar disorder risk allele at CACNA1C also confers risk of recurrent major depression and of schizophrenia. | Green EK et al. | β | 2010 | β |
| The CRF system, stress, depression and anxiety-insights from human genetic studies. | Binder EB et al. | β | 2010 | β |
| The end of behavioral genetics? 2008. | McGue M | β | 2010 | β |
| The genetics of affective disorder and suicide. | McGuffin P et al. | β | 2010 | β |
| The genetics of major depression: moving beyond the monoamine hypothesis. | Shyn SI et al. | β | 2010 | β |
| The Internet-based MGS2 control sample: self report of mental illness. | Sanders AR et al. | β | 2010 | β |
| The role of genetics in the etiology of schizophrenia. | Gejman PV et al. | β | 2010 | β |
| Translational research in bipolar disorder: emerging insights from genetically based models. | Chen G et al. | β | 2010 | β |
| Two-dimensional genome scan identifies multiple genetic interactions in bipolar affective disorder. | Fullerton JM et al. | β | 2010 | β |
| Variations in FKBP5 and BDNF genes are suggestively associated with depression in a Swedish population-based cohort. | Lavebratt C et al. | β | 2010 | β |
| Ξ²-catenin promoter ChIP-chip reveals potential schizophrenia and bipolar disorder gene network. | Pedrosa E et al. | β | 2010 | β |
| Addiction genetics and pleiotropic effects of common haplotypes that make polygenic contributions to vulnerability to substance dependence. | Uhl GR et al. | β | 2009 | β |
| A genomewide association study of response to lithium for prevention of recurrence in bipolar disorder. | Perlis RH et al. | β | 2009 | β |
| A genome-wide linkage and association scan reveals novel loci for autism. | Weiss LA et al. | β | 2009 | β |
| A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB. | Need AC et al. | β | 2009 | β |
| Allele variants in functional MicroRNA target sites of the neurotrophin-3 receptor gene (NTRK3) as susceptibility factors for anxiety disorders. | MuiΓ±os-Gimeno M et al. | β | 2009 | β |
| Alternatively Spliced Genes as Biomarkers for Schizophrenia, Bipolar Disorder and Psychosis: A Blood-Based Spliceome-Profiling Exploratory Study. | Glatt SJ et al. | β | 2009 | β |
| A PCA-based method for ancestral informative markers selection in structured populations. | Zhang F et al. | β | 2009 | β |
| Association analysis of group II metabotropic glutamate receptor genes (GRM2 and GRM3) with mood disorders and fluvoxamine response in a Japanese population. | Tsunoka T et al. | β | 2009 | β |
| Association between sodium- and potassium-activated adenosine triphosphatase alpha isoforms and bipolar disorders. | Goldstein I et al. | β | 2009 | β |
| Association between the serotonin 2A receptor gene and bipolar affective disorder in an Australian cohort. | McAuley EZ et al. | β | 2009 | β |
| Association study of 21 circadian genes with bipolar I disorder, schizoaffective disorder, and schizophrenia. | Mansour HA et al. | β | 2009 | β |
| Bipolar disorder and mechanisms of action of mood stabilizers. | Rapoport SI et al. | β | 2009 | β |
| Bipolar disorder: emotional dysregulation and neuronal vulnerability. | Stein DJ et al. | β | 2009 | β |
| Bipolar disorder: from genes to behavior pathways. | Martinowich K et al. | β | 2009 | β |
| Chromosome 13q13-q14 locus overlaps mood and psychotic disorders: the relevance for redefining phenotype. | Maziade M et al. | β | 2009 | β |
| Chromosome 8p as a potential hub for developmental neuropsychiatric disorders: implications for schizophrenia, autism and cancer. | TabarΓ©s-Seisdedos R et al. | β | 2009 | β |
| Circadian polymorphisms associated with affective disorders. | Kripke DF et al. | β | 2009 | β |
| Classifying mood disorders by age-at-onset instead of polarity. | Benazzi F | β | 2009 | β |
| Common and rare variants of DAOA in bipolar disorder. | Maheshwari M et al. | β | 2009 | β |
| Common genetic variants on 5p14.1 associate with autism spectrum disorders. | Wang K et al. | β | 2009 | β |
| Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. | International Schizophrenia Consortium et al. | β | 2009 | β |
| Convergent functional genomics of genome-wide association data for bipolar disorder: comprehensive identification of candidate genes, pathways and mechanisms. | Le-Niculescu H et al. | β | 2009 | β |
| Convergent genome wide association results for bipolar disorder and substance dependence. | Johnson C et al. | β | 2009 | β |
| Criteria for the selection of single nucleotide polymorphisms in pathway pharmacogenetics: TNF inhibitors as a case study. | Kooloos WM et al. | β | 2009 | β |
| Disruptive insights in psychiatry: transforming a clinical discipline. | Insel TR | β | 2009 | β |
| Evidence-based guidelines for treating bipolar disorder: revised second edition--recommendations from the British Association for Psychopharmacology. | Goodwin GM et al. | β | 2009 | β |
| Evidence for genetic association of RORB with bipolar disorder. | McGrath CL et al. | β | 2009 | β |
| Expression of mitochondrial complex I subunit gene NDUFV2 in the lymphoblastoid cells derived from patients with bipolar disorder and schizophrenia. | Washizuka S et al. | β | 2009 | β |
| Extracting a needle from a haystack: reanalysis of whole genome data reveals a readily translatable finding. | Keers R et al. | β | 2009 | β |
| Family and genetic association studies of bipolar disorder in children. | Mick E et al. | β | 2009 | β |
| Family-based association of YWHAH in psychotic bipolar disorder. | Grover D et al. | β | 2009 | β |
| Family-based association study of Neuregulin 1 with psychotic bipolar disorder. | Goes FS et al. | β | 2009 | β |
| Family-based association study of the BDNF, COMT and serotonin transporter genes and DSM-IV bipolar-I disorder in children. | Mick E et al. | β | 2009 | β |
| Findings from bipolar disorder genome-wide association studies replicate in a Finnish bipolar family-cohort. | Ollila HM et al. | β | 2009 | β |
| From age correction to genome-wide association. | Cohen-Woods S et al. | β | 2009 | β |
| Genetic calcium signaling abnormalities in the central nervous system: seizures, migraine, and autism. | Gargus JJ | β | 2009 | β |
| Genetic overlap between autism, schizophrenia and bipolar disorder. | Carroll LS et al. | β | 2009 | β |
| Genetics of bipolar disorder: successful start to a long journey. | Craddock N et al. | β | 2009 | β |
| Genetics of psychosis; insights from views across the genome. | O'Donovan MC et al. | β | 2009 | β |
| Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry. | Scott LJ et al. | β | 2009 | β |
| Genomewide association studies: history, rationale, and prospects for psychiatric disorders. | Psychiatric GWAS Consortium Coordinating Committee et al. | β | 2009 | β |
| Genome-wide association studies in ADHD. | Franke B et al. | β | 2009 | β |
| Genome-wide association study of alcohol dependence. | Treutlein J et al. | β | 2009 | β |
| Genome-wide association study of bipolar disorder in European American and African American individuals. | Smith EN et al. | β | 2009 | β |
| Genomic landscape of a three-generation pedigree segregating affective disorder. | Yang S et al. | β | 2009 | β |
| Glucocorticoid receptor polymorphisms in major depression. | Claes S | β | 2009 | β |
| Imaging phenotypes of major depressive disorder: genetic correlates. | Savitz JB et al. | β | 2009 | β |
| Lessons from STEP-BD for the treatment of bipolar depression. | Nierenberg AA | β | 2009 | β |
| Linkage and association studies of anxiety disorders. | Hamilton SP | β | 2009 | β |
| Lithium: a key to the genetics of bipolar disorder. | Cruceanu C et al. | β | 2009 | β |
| MicroRNAs in mental health: from biological underpinnings to potential therapies. | Hunsberger JG et al. | β | 2009 | β |
| New hope for pharmacogenetic testing. | Nurnberger JI | β | 2009 | β |
| No association between DGKH and bipolar disorder in a Scandinavian case-control sample. | Tesli M et al. | β | 2009 | β |
| No evidence for excess runs of homozygosity in bipolar disorder. | Vine AE et al. | β | 2009 | β |
| Pathways-based analyses of whole-genome association study data in bipolar disorder reveal genes mediating ion channel activity and synaptic neurotransmission. | Askland K et al. | β | 2009 | β |
| Pharmacogenetics and pharmacogenomics of anticancer agents. | Huang RS et al. | β | 2009 | β |
| Preliminary genome-wide association study of bipolar disorder in the Japanese population. | Hattori E et al. | β | 2009 | β |
| Putting the 'human' back in genetics: modeling the extended kinships of twins. | Eaves L | β | 2009 | β |
| Recent advances in bipolar disorder pharmacotherapy: focus on bipolar depression and rapid cycling. | Datta V et al. | β | 2009 | β |
| Searching genetic risk factors for schizophrenia and bipolar disorder: learn from the past and back to the future. | Alaerts M et al. | β | 2009 | β |
| Singleton deletions throughout the genome increase risk of bipolar disorder. | Zhang D et al. | β | 2009 | β |
| Suicide neurobiology. | Ernst C et al. | β | 2009 | β |
| The genetics of bipolar disorder. | Barnett JH et al. | β | 2009 | β |
| The genetics of Tourette syndrome: a review. | O'Rourke JA et al. | β | 2009 | β |
| The psychoses: cluster 3 of the proposed meta-structure for DSM-V and ICD-11. | Carpenter WT et al. | β | 2009 | β |
| An interview with... Cliff Tabin. | Tabin C | β | 2008 | β |
| Chromosome abnormalities, mental retardation and the search for genes in bipolar disorder and schizophrenia. | Blackwood DH et al. | β | 2008 | β |
| Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. | Ferreira MA et al. | β | 2008 | β |
| Copy variations in schizophrenia and bipolar disorder. | Lachman HM | β | 2008 | β |
| Early intervention in bipolar disorder, part II: therapeutics. | Salvadore G et al. | β | 2008 | β |
| Epigenetic and pharmacoepigenomic studies of major psychoses and potentials for therapeutics. | Abdolmaleky HM et al. | β | 2008 | β |
| Genetic causality in schizophrenia and bipolar disorder: out with the old and in with the new. | Porteous D | β | 2008 | β |
| Genome-wide association scan of attention deficit hyperactivity disorder. | Neale BM et al. | β | 2008 | β |
| Molecular neurobiology of bipolar disorder: a disease of 'mood-stabilizing neurons'? | Kato T | β | 2008 | β |
| Psychiatric genetics: progress amid controversy. | Burmeister M et al. | β | 2008 | β |
| The End of Behavioral Genetics? | McGue M | β | 2008 | β |
| The positives, protocols, and perils of genome-wide association. | Neale BM et al. | β | 2008 | β |