Acetylcholine as a neuromodulator: cholinergic signaling shapes nervous system function and behavior.

paper Cited Public

Authors: Picciotto, Marina R; Higley, Michael J; Mineur, Yann S
Year: 2012
Journal: Neuron
PMID: 23040810
DOI: 10.1016/j.neuron.2012.08.036
PMCID: PMC3466476

Figure 1

Sites of action for nicotinic and muscarinic acetylcholine receptorsNicotinic (nAChR) and muscarinic (mAChR) acetylcholine receptors are localized both pre- and post-synaptically. Presynaptic mAChRs (M2, M4) are largely inhibitory, and act as inhibitory autoreceptors on cholinergic terminals, with M2 the predominant autoreceptor in hippocampus and cerebral cortex, and M4 predominant in striatum (Wess, 2003b; Wess et al., 2003). Post-synaptic mAChRs can be either inhibitory (M2, M4) or excitatory (M1, M3, M5) (Wess, 2003b; Wess et al., 2003). Presynaptic nAChRs induce release of a number of neurotransmitters including GABA, glutamate, dopamine, serotonin, norepinephrine and acetylcholine (McGehee et al., 1995; Wonnacott, 1997). Postsynaptic nAChRs depolarize neurons, increase their firing rate and can contribute to long-term potentiation (Bucher and Goaillard, 2011; Ge and Dani, 2005; Ji et al., 2001; Kawai et al., 2007; Mansvelder and McGehee, 2000; Picciotto et al., 1995; Picciotto et al., 1998; Radcliffe and Dani, 1998; Wooltorton et al., 2003).

Figure 2

Effects of acetylcholine on activity of dopamine neurons in the mesolimbic circuitSalient cues associated with primary rewards increase activity of pedunculopontine tegmental area (PPTg) neurons, inducing acetylcholine release in the ventral tegmental area (VTA) (Futami et al., 1995; Omelchenko and Sesack, 2006). Acetylcholine increases firing of dopamine (DA) neurons in the VTA and is likely to be important for burst firing of these neurons (Maskos, 2008). Salient cues associated with rewards also induce a pause in firing of tonically active cholinergic neurons (ACh TAN) in the nucleus accumbens (NAc) (Goldberg and Reynolds, 2011). Decreased release of ACh onto terminals in NAc attenuates DA release due to tonic firing of DA neurons, while preserving DA release in response to phasic firing (Exley and Cragg, 2008).

Figure 3

Effects of acetylcholine on activity of cortical neuronsSalient cues induce acetylcholine release onto interneurons targeting the apical dendrites of cortical pyramidal neurons, resulting in rapid inhibition of pyramidal cells (Arroyo et al., 2012; Couey et al., 2007; Fanselow et al., 2008; Ferezou et al., 2002; Gulledge et al., 2007; Kawaguchi and Kubota, 1997). Acetylcholine subsequently depolarizes pyramidal neurons through M1 mAChRs (Delmas and Brown, 2005; McCormick and Prince, 1985, 1986). Acetylcholine also activates stimulatory α4β2 nAChRs on glutamatergic thalamocortical terminals (Gil et al., 1997; Lambe et al., 2003; Oldford and Castro-Alamancos, 2003) and inhibitory M2 mAChRs on GABAergic terminals of parvalbumin-expressing (PV) interneurons (Kruglikov and Rudy, 2008). Activation of PV interneurons enhances stimulation of pyramidal neuron firing by thalamocortical inputs (Gabernet et al., 2005; Higley and Contreras, 2006; Kruglikov and Rudy, 2008). Acetylcholine also suppresses cortico-cortical transmission through inhibitory M2 mAChRs on pyramidal cell axon terminals (Gil et al., 1997; Hsieh et al., 2000; Kimura and Baughman, 1997; Oldford and Castro-Alamancos, 2003), reducing intra-cortical communication while preserving responses to thalamic inputs (Kimura et al., 1999).

Figure 4

Effects of acetylcholine on hippocampal-amygdala stress responseStress increases acetylcholine release in the hippocampus and frontal cortex (Mark et al., 1996) and impairs signaling in the prefrontal cortex (PFC) (Arnsten, 2009). The hippocampus provides inhibitory feedback to the amygdala through inhibition of the hypothalamic-pituitary-adrenal (HPA) axis (Tasker and Herman, 2011) whereas the PFC can normally decrease basolateral amygdala activity through projections to the intercalated nucleus (Manko et al., 2011; Pinard et al., 2012). The effects of stress-induced acetylcholine release on output of hippocampus and cortex is unknown, but cholinergic modulation of cortico-amygdala glutamatergic connections strengthens associations between environmental stimuli and stressful events (Mansvelder et al., 2009).

#	Section	Preview
20	BRAIN SYSTEMS MODULATED BY ACH SIGNALING — Mesolimbic DA system, addiction and reward	In contrast to the increased firing rate of cholinergic neurons in the PPTg in response to…
21	BRAIN SYSTEMS MODULATED BY ACH SIGNALING — Mesolimbic DA system, addiction and reward	in striatum and NAc is also thought to be critical for mediating the association between drugs of…
22	BRAIN SYSTEMS MODULATED BY ACH SIGNALING — Mesolimbic DA system, addiction and reward	These findings suggest that salient sensory stimuli in the environment, such as those associated…
23	BRAIN SYSTEMS MODULATED BY ACH SIGNALING — Mesolimbic DA system, addiction and reward	The behavioral role of individual ACh receptor subtypes in NAc is more complex, however. Consistent…
24	BRAIN SYSTEMS MODULATED BY ACH SIGNALING — Mesolimbic DA system, addiction and reward	A number of studies have focused on the ability of the habenula, particularly the MHb to oppose the…
25	BRAIN SYSTEMS MODULATED BY ACH SIGNALING — Mesolimbic DA system, addiction and reward	Taken together, these studies suggest that point-to-point ACh signaling could have opposing…
26	BRAIN SYSTEMS MODULATED BY ACH SIGNALING — Cortex and attention	Numerous studies indicate that ACh plays an important and diverse role in the regulation of cortical…
27	BRAIN SYSTEMS MODULATED BY ACH SIGNALING — Cortex and attention	The cellular mechanisms underlying the effects of ACh on cortical circuits have been investigated at…
28	BRAIN SYSTEMS MODULATED BY ACH SIGNALING — Cortex and attention	ACh also modulates synaptic transmission in cortical circuits (Figure 3). Activation of α4β2…
29	BRAIN SYSTEMS MODULATED BY ACH SIGNALING — Cortex and attention	In contrast, mAChRs located on pyramidal cell axon terminals suppress cortico-cortical transmission…
30	BRAIN SYSTEMS MODULATED BY ACH SIGNALING — Cortex and attention	Although the cellular and synaptic effects of ACh described above provide a potential mechanism for…
31	BRAIN SYSTEMS MODULATED BY ACH SIGNALING — Cortex and attention	through M1 mAChRs would dominate in neurons with fully-replenished stores. Furthermore, studies…
32	BRAIN SYSTEMS MODULATED BY ACH SIGNALING — Cortex and attention	ACh also modulates cortical circuits over longer time scales by influencing the plasticity of…
33	BRAIN SYSTEMS MODULATED BY ACH SIGNALING — Cortex and attention	At the cellular level, cholinergic agonists enhance LTP of glutamatergic association fibers in the…
34	BRAIN SYSTEMS MODULATED BY ACH SIGNALING — Cortex and attention	The pleiotropic effects of ACh on cortical circuits described above are likely to underlie its…
35	BRAIN SYSTEMS MODULATED BY ACH SIGNALING — Hypothalamus and food intake	The role of ACh in control of autonomic functions is well known, but it is likely that actions of…
36	BRAIN SYSTEMS MODULATED BY ACH SIGNALING — Hypothalamus and food intake	A small number of studies have investigated the role of ACh signaling in the hypothalamus, which…
37	BRAIN SYSTEMS MODULATED BY ACH SIGNALING — Hypothalamus and food intake	which express cholinergic markers, were activated in response to presentation of food when the…
38	BRAIN SYSTEMS MODULATED BY ACH SIGNALING — Hypothalamus and food intake	At the cellular level, stimulation of nAChRs and mAChRs on lateral hypothalamic (LH) neurons…
39	BRAIN SYSTEMS MODULATED BY ACH SIGNALING — Hypothalamus and food intake	vitro due to more rapid desensitization of nAChR responses in NPY neurons, and in vivo, as evidenced…

Name	Type
acetylcholine	drug
acetylcholinesterase	drug
ACh	drug
ACHE	gene
acute stress	phenotype
addiction	phenotype
adenylyl cyclase	drug
alcohol self-administration	phenotype
amygdala	anatomy
arcuate nucleus	anatomy
Association cortex local	anatomy
Atropine	drug
attention	phenotype
auditory cortex	anatomy
Auditory discrimination local	phenotype
Autonomic ganglia local	anatomy
Aversive memory local	phenotype
Basal forebrain complex local	anatomy
baseline excitability local	phenotype
basolateral amygdala	anatomy
behavioral consequences	phenotype
binocular cortex local	anatomy
body weight	phenotype
brain	anatomy
brain circuits	anatomy
brain stem	anatomy
breakpoint for progressive ratio responding local	phenotype
CA1	anatomy
CA3	anatomy
calcineurin	drug
Calcium ion	drug
central nervous system	anatomy
c-fos	gene
Cholinergic agents local	drug
cholinergic agonists	drug
Chrm1	gene
CHRM3	gene
CHRM4	gene
CHRNA2	gene
Chrna3	gene
Chrna4	gene
CHRNA5	gene
Chrna6	gene
Chrna7	gene
Chrnb2	gene
Chrnb3	gene
Chrnb4	gene
cocaine	phenotype
cocaine self-administration	phenotype
control subjects	cohort
cortex	anatomy
Cortical activity	phenotype
cortical neurons	anatomy
Corticocortical synapse local	anatomy
cortico-cortical transmission local	phenotype
Cortico-cortical transmission local	phenotype
Corticostriatal synapse	anatomy
Corticothalamic synapse local	anatomy
craving	phenotype
CRF	drug
Cue detection local	phenotype
decision making	phenotype
depression	phenotype
Depression-like endophenotypes local	phenotype
diagonal band of Broca	anatomy
dopamine	drug
dopamine release	drug
Dopaminergic firing local	phenotype
dopaminergic neurons	anatomy
drug dependence	phenotype
drug-seeking behavior	phenotype
entorhinal cortex	anatomy
Excitability of cortical pyramidal neurons local	phenotype
fear	phenotype
fear conditioning	phenotype
fear-conditioning local	phenotype
feeding behavior	phenotype
Firing of groups of neurons local	phenotype
Flinders rat model local	cohort
food intake	phenotype
Food-seeking behavior local	phenotype
forebrain	anatomy
Fos	gene
FOS expression local	phenotype
GABA	phenotype
GABAergic synapse local	phenotype
Gamma-aminobutyric acid	drug
Gi/o protein	drug
glucagon	drug
glutamate	drug
glutamatergic neurons	phenotype
Glutamatergic synapse local	phenotype
Gq protein local	drug
habenula	anatomy
High-fat/high-sugar diet local	drug
Hippocampal excitability local	phenotype
hippocampus	anatomy
History of depression patients local	cohort
humans	cohort
hunger	phenotype
Huntington’s disease	phenotype
hypothalamic-pituitary-adrenal axis	anatomy
hypothalamus	anatomy
Inhibition of cholinergic terminals local	phenotype
insulin	drug
Intercalated nucleus local	anatomy
Intercalated Nucleus local	anatomy
Intra-cortical communication local	phenotype
KCNQ	gene
lateral hypothalamus	anatomy
Laterodorsal tegmental area local	anatomy
laterodorsal tegmental nucleus	anatomy
LDTg	anatomy
learning	phenotype
learning and memory	phenotype
locomotion	phenotype
locomotor effects of cocaine	phenotype
long-term depression	phenotype
long-term potentiation	phenotype
LTP	phenotype
L-type calcium channel	drug
Lynx1 local	gene
M1 mAChR local	drug
M1 muscarinic receptor local	drug
M2 muscarinic receptor local	drug
M3 muscarinic receptor	drug
M4 muscarinic receptor local	drug
M5 muscarinic receptor local	drug
M5-type mAChR local	drug
major depressive disorder	phenotype
medial habenula	anatomy
medial prefrontal cortex	anatomy
medial septum	anatomy
Median eminence local	anatomy
memory	phenotype
Mesolimbic DA system local	anatomy
mesolimbic system	anatomy
Metabolic need local	phenotype
metabolism	phenotype
mice	cohort
midbrain	anatomy
monkeys	cohort
monocular area of superficial visual cortex local	anatomy
mood disorders	phenotype
motivational effects	phenotype
motivation to lever press for nicotine local	phenotype
Movement disorders local	phenotype
Muscarinic acetylcholine receptor	drug
Muscarinic acetylcholine receptor local	gene
muscarinic acetylcholine receptors local	drug
Muscarinic acetylcholine receptors local	drug
NAc	anatomy
NAc cholinergic neurons local	anatomy
neocortex	anatomy
Neuromuscular junction local	anatomy
neuronal excitability	phenotype
neurotrophin	drug
nicotine	drug
nicotine self-administration	phenotype
nicotinic acetylcholine receptor	drug
NMDA-type glutamate receptors local	drug
Non-human primate cortex local	anatomy
norepinephrine	drug
NPY	gene
NPY neuron firing local	phenotype
nucleus accumbens	anatomy
nucleus basalis	anatomy
Nucleus basalis of Meynert local	anatomy
Ocular dominance plasticity local	phenotype
Orexin-positive neuron local	phenotype
Organophosphate inhibitors local	drug
orienting behaviors local	phenotype
Paired facilitation local	phenotype
Parkinson’s disease	phenotype
Pedunculopontine tegmental area local	anatomy
Perforant inputs local	anatomy
PFC	anatomy
phospholipase C	drug
Physostigmine local	drug
piriform cortex	anatomy
Pomc	gene
POMC neuron firing local	phenotype
Positive and Negative Affect Schedule	phenotype
PPTg	anatomy
PPTg cholinergic neurons local	anatomy
prefrontal cortex	anatomy
Presynaptic release of neurotransmitters local	phenotype
primary reinforcing effects local	phenotype
primary visual cortex	anatomy
Pro-opiomelanocortin peptide local	drug
pyramidal neurons	anatomy
relapse	phenotype
REM sleep	phenotype
reward	phenotype
rewarding effects of cocaine	phenotype
reward prediction local	phenotype
rodents	cohort
Schaeffer collaterals local	anatomy
scopolamine	drug
Sensory attention local	phenotype
serotonin	drug
signal detection	phenotype
signal-to-noise ratio	phenotype
sleep patterns	phenotype
Slow wave sleep local	phenotype
somatosensory cortex	anatomy
Stimulus-response task local	phenotype
stress	phenotype
Stress relief local	phenotype
stress response	phenotype
Striatal cholinergic neurons local	anatomy
striatum	anatomy
substantia innominata	anatomy
sustained attention	phenotype
synaptic plasticity	phenotype
temperature regulation	phenotype
Thalamocortical pathway local	anatomy
thalamocortical projections	anatomy
Thalamocortical synapse local	anatomy
thalamus	anatomy
theta oscillations	phenotype
tobacco smoke	phenotype
Tourette’s individuals local	cohort
Tourette’s syndrome	phenotype
Uncertainty response local	phenotype
ventral tegmental area	anatomy
visual attention	phenotype
VTA	anatomy
VTA DA neurons local	anatomy
Wakefulness	phenotype
white matter	anatomy
α4β2 nAChR	drug
α4β2 nicotinic receptor local	drug
α6/β2 class of nAChRs local	drug
α7 nicotinic acetylcholine receptor	drug
α7-type nAChRs local	drug

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In this knowledge base

Title	Year	PMID
Genetic and neurophysiological correlates of the age of onset of alcohol use disorders in adolescents and young adults.	2013	23963516

External

Title	Authors	Journal	Year	Link
Activity-Based Multimodal Probes Uncover the AChE-ADGRB Axis in Cellular and Murine Models of Depression.	Xiang J et al.	—	2026	→
Altered acetylcholine modulations and corticoaccumbal pathway in P11-linked social dysfunction.	Dautan D et al.	—	2026	→
Biological substrates of structure-function coupling in brain networks.	Fotiadis P et al.	—	2026	→
Cardiac endogenous transmitter system: molecular features, functions, and clinical implications.	Xie D et al.	—	2026	→
Chronic effects of traumatic brain injury and the impact of biperiden treatment in a male rat model.	Sanabria V et al.	—	2026	→
Combined analysis of network toxicology and transcriptomics revealed the potential mechanism of EPH-induced neurotoxicity in zebrafish.	Deng Y et al.	—	2026	→
Combined developmental toxicity of organophosphorus flame retardant TCEP and lead on zebrafish.	Zhang X et al.	—	2026	→
Comparative transcriptomic analysis of the hypothalamus between tumbler and white king pigeons.	Peng Y et al.	—	2026	→
Compensatory hallucinogenesis across three neuropsychiatric disorders: a Bayesian account.	Vin R et al.	—	2026	→
Consequences of iron exposure and glutathione depletion on redox balance, lipidome, and neurotransmission in C. elegans.	Gremme A et al.	—	2026	→
Dataset of Oddball Paradigm experiment in the Auditory Cortex and the effect of acetylcholine.	Vázquez-Borsetti P et al.	—	2026	→
Deep brain stimulation of the nucleus basalis of Meynert in neurodegenerative diseases with cognitive impairment: An update on evidence and mechanisms.	Liu X et al.	—	2026	→
Development and analysis of the adverse outcome pathway network for neurotoxicity.	Hui X et al.	—	2026	→
Effects of aerobic exercise on depression-like behaviors and hippocampal transcriptomics in CSDS-induced adolescent mice.	Sha L et al.	—	2026	→
Ephedrine-disrupted synaptogenesis signaling and behavioral abnormalities in adult zebrafish.	Deng Y et al.	—	2026	→
From comorbidity to continuum: Alzheimer's disease and epilepsy are connected-now what?	Alves SS et al.	—	2026	→
Globally patterned locus coeruleus-norepinephrine neuron-pericyte coupling orchestrates brain-wide vascular dynamics.	Sun L et al.	—	2026	→
Impact of distinct neurotransmitter release modes on neuronal signaling.	Zhang KJ et al.	—	2026	→
Is levodopa induced freezing of gait a paradox or an expected phenomenon?: a clinico-pathophysiological hypothesis.	Jha S et al.	—	2026	→
Layer 6 is a hub for cholinergic modulation in the mouse auditory cortex.	Vattino LG et al.	—	2026	→
<i>Chrysanthemum zawadskii</i> Flower Extract Rescues Inflammatory Cognitive Impairment.	Choi Y et al.	—	2026	→
Lymphocyte-derived cholinergic circuits modulate germinal center output and B cell activation.	Nechanitzky D et al.	—	2026	→
Medicago sativa alleviates behavioral impairments and oxidative stress in the cerebrum and cerebellum of ovariectomized mice.	Ghorbel Koubaa F et al.	—	2026	→
Modulation of metastable ensemble dynamics explains the inverted-U relationship between tone discriminability and arousal in auditory cortex.	Papadopoulos L et al.	—	2026	→
mPFC Synaptosome Proteomics Reveals Novel Pathways and Muscarinic Receptor Changes in a Learned Helplessness Mouse Model.	Abdulla ZI et al.	—	2026	→
Nanogel Delivery of Plumbagin from Nepenthes Khasiana Attenuates Neuroinflammation and Cognitive Decline in Alzheimer's Mice Models.	Zhang X et al.	—	2026	→
Nanotechnology-based targeted delivery strategies for the treatment of Alzheimer's disease.	Yuan X et al.	—	2026	→
Nanotip acetylcholine biosensor reveals cholinergic differentiated SH-SY5Y cells release partial vesicle content during exocytosis.	Wang Y et al.	—	2026	→
Neurometabolic rewiring in squid (Sepioteuthis lessoniana) optic lobes drives behavioral plasticity and visual integration under environmental acidification.	Allen GJP et al.	—	2026	→
Nicotine Disrupts Top-Down Habenular Control Over Cholinergic Inputs to the Ventral Tegmental Area to Increase Motivational Valence of Food Rewards.	Campos RC et al.	—	2026	→
Nicotinic acetylcholine receptors function with adhesion molecule SAX-7 to reverse cell orientation during migration.	Antonio J et al.	—	2026	→
Novel drug treatments for schizophrenia.	Coyle JT et al.	—	2026	→
Rising Stars: In vivo Monitoring of Neurochemical Dynamics by Genetically Encoded Neuromodulator Sensors.	Fu S et al.	—	2026	→
Rocket-inspired gas-propelled microneedles engineered with borneol-NLCs-loaded hierarchical cavities for enhanced brain delivery in Alzheimer's therapy.	Shen S et al.	—	2026	→
Sex differences in interactions between the muscarinic-1 and orexin-1 receptors on cognitive flexibility in rats.	Li M et al.	—	2026	→
Targeting the Gut-Brain-Ferroptosis Axis: Molecular Mechanisms and Therapeutic Potential in Alzheimer's Disease and Epilepsy.	Fawzy MN et al.	—	2026	→
The Effect of the Anticonvulsant Topiramate on Acetylcholine-Induced Calcium Signals is Linked to Sirt-1 Activity.	Kümmel ML	—	2026	→
The effects of polysaccharides from <i>Schizophyllum commune</i> (Fr.) on amyloid-β and GFAP-induced neuronal injury in hippocampal regions of hyperlipidemia-affected rats.	Thipthong N et al.	—	2026	→
Too aroused to be attractive.	Satchell M et al.	—	2026	→
Toxic Effects of Polystyrene Microplastics and Sulfamethoxazole on Early Neurodevelopment in Embryo-Larval Zebrafish (<i>Danio rerio</i>).	Meng F et al.	—	2026	→
Trace conditioning: insights from invertebrate models on bridging the temporal gap.	Rivi V et al.	—	2026	→
Transcriptional and functional profiles of muscarinic receptor-expressing neurons in primate lateral prefrontal and anterior cingulate cortices.	Tsolias A et al.	—	2026	→
Unraveling the impact of risk factors on the ferroptosis-Alzheimer's disease link for early detection.	Singh P et al.	—	2026	→
Acetylcholine and Depression: Scrutinizing Future Therapeutic Targets for Novel Drug Development.	Pannu A et al.	—	2025	→
Acetylcholine and muscarinic receptor targeting in bipolar disorder: does xanomeline-trospium chloride and other investigational muscarinic agonists hold promise as mechanistically informed treatments for manic episodes, mixed features and cognitive deficits in bipolar disorder?	McIntyre RS	—	2025	→
Acetylcholine from tuft cells promotes M2 macrophages polarization in Hirschsprung-associated enterocolitis.	Zheng Z et al.	—	2025	→
Acetylcholine modulates prefrontal outcome coding during threat learning under uncertainty.	Tu G et al.	—	2025	→
Acetylcholine nicotinic receptors play a central role in the modulation of rewarding behaviors by interacting with dopamine transmission: evidence from male rat sexual behavior.	Hernández-Colín AE et al.	—	2025	→
Acute Hypobaric Hypoxia Causes Alterations in Acetylcholine-Mediated Signaling Through Varying Expression of Muscarinic Receptors in the Prefrontal Cortex and Cerebellum of Rats' Brain.	Sharma NK et al.	—	2025	→
Adolescent nicotine exposure and persistent neurocircuitry changes: unveiling lifelong psychiatric risks.	Reynolds LM et al.	—	2025	→
AI-Validated Brain Targeted mRNA Lipid Nanoparticles with Neuronal Tropism.	Sela M et al.	—	2025	→
Alterations in serum metabolomics predict drug-resistant epilepsy.	Kang W et al.	—	2025	→
A molecular probe for detecting cholinesterase activity in MRI.	Sen S et al.	—	2025	→
A New Era of Muscarinic Acetylcholine Receptor Modulators in Neurological Diseases, Cancer and Drug Abuse.	Tsimpili H et al.	—	2025	→
A Novel Combined Mung Bean and Mulberry Powder: Combination Index and Shelf Life of Total Phenolic, Anthocyanin, and GABA Contents and Neuroprotective Activity.	Polyiam P et al.	—	2025	→
[Anticholinergic burden in the elderly].	Rodríguez Casal M	—	2025	→
Anticholinergic drugs and dementia risk: Using stem cell-based studies to complement pharmacoepidemiology.	Schwarze-Taufiq TA et al.	—	2025	→
Assessment of neurobehavioural traits under gnotobiotic conditions: an approach for multiple analyses in the same mouse.	Rutsch A et al.	—	2025	→
Assessment of Neurotoxic Mechanisms of Individual and Binary Mixtures of Cobalt, Nickel and Lead in Hippocampal Neuronal Cells.	Olasehinde TA et al.	—	2025	→
Association of a Brief Computerized Cognitive Assessment With Cholinergic Neurotransmission: Assessment Validation Study.	Attarha M et al.	—	2025	→
Atropine restores retinal glutamate / γ-aminobutyric acid levels in vitro in an experimental chick model of myopia.	Lloyd JT et al.	—	2025	→
Binding mechanism and antagonism of the vesicular acetylcholine transporter VAChT.	Ma Q et al.	—	2025	→
Blood oxygenation level-dependent responses in neuromodulatory nuclei and their associations with attention and memory across age groups.	Riley E et al.	—	2025	→
Carbon microelectrodes for the measurement of neurotransmitters with fast-scan cyclic voltammetry: methodology and applications.	Alyamni N et al.	—	2025	→
Cell-type-specific cholinergic control of granular retrosplenial cortex with implications for angular velocity coding across brain states.	Jedrasiak-Cape I et al.	—	2025	→
Cellular and molecular associations with intrinsic brain organization.	Feng G et al.	—	2025	→
Cellular and organismal function of choline metabolism.	Kenny TC et al.	—	2025	→
Changes in neurotransmitter metabolic profiles in copper-loaded rats as assessed by mass spectrometry imaging and the effect of Gandouling intervention.	Hu Y et al.	—	2025	→
Chlorpyrifos and neuroendocrine function: Concerns for research with free-living mammal populations.	Mitzel KM et al.	—	2025	→
Cholinergic modulation mediates attentional mechanism to enhance coherence between cortical layers in macaque V1 and V4.	Sajedin A et al.	—	2025	→
Cholinergic network modulation in disinhibited eating behavior.	Hesse S et al.	—	2025	→
Cholinergic neuronal activity promotes diffuse midline glioma growth through muscarinic signaling.	Drexler R et al.	—	2025	→
Cholinergic regulation of thymocyte negative selection.	Liu S et al.	—	2025	→
Cholinergic T cells revitalize the tumor immune microenvironment: TIME to ChAT.	Zheng C et al.	—	2025	→
Cholinergic tone abnormalities and relationships with smoking severity in human cigarette smokers: exploratory positron emission tomography study using [<sup>18</sup>F]VAT.	Moeller SJ et al.	—	2025	→
Comprehensive medicinal chemistry survey highlights a portfolio of lead molecules for Alzheimer's disease therapy.	Bhansali PR et al.	—	2025	→
Cortical acetylcholine response to deep brain stimulation of the basal forebrain in mice.	Shanazz K et al.	—	2025	→
Curcumin-Piperine Self-Nanoemulsifying Delivery in <i>Zanthoxylum rhetsa</i> Seed Oil Attenuates Cuprizone-Induced Frontal Cortex Toxicity.	Alam MZ et al.	—	2025	→
Decoding the neuroimmune axis in colorectal cancer: From neural circuitry to therapeutic innovation.	Li Y et al.	—	2025	→
Deep brain stimulation of nucleus basalis of meynert: Effect of stimulation mode and duration on learning in rat model of dementia.	Kumbhare D et al.	—	2025	→
Developing personalized treatment strategies for Parkinson's disease based on disease subtypes.	Hey GE et al.	—	2025	→
Different Mechanisms in Doxorubicin-Induced Neurotoxicity: Impact of BRCA Mutations.	Bhatt KS et al.	—	2025	→
Dual Monitoring of Blood Acetylcholinesterase Content and Catalytic Activity Utilizing Fluorometry-Integrated Surface Plasmon Resonance.	Xie Y et al.	—	2025	→
Dynorphin modulates reward-seeking actions through a pallido-amygdala cholinergic circuit.	Sun Q et al.	—	2025	→
Editorial: Mechanisms of cholinergic transmission in motivation and cognition.	Francis TC et al.	—	2025	→
Effects of a Natural Polyherbal Extract on Alleviating Scopolamine-Induced Memory Deficits in C57BL/6 Mice via Enhancing Cholinergic Function.	Kwon H et al.	—	2025	→
Effects of Computerized Cognitive Training on Vesicular Acetylcholine Transporter Levels using [18F]Fluoroethoxybenzovesamicol Positron Emission Tomography in Healthy Older Adults: Results from the Improving Neurological Health in Aging via Neuroplasticity-based Computerized Exercise (INHANCE) Randomized Clinical Trial.	Attarha M et al.	—	2025	→
Effects of levetiracetam an antiepileptic drug on the multi-biological parameters in African catfish Clarias gariepinus (Burchell, 1822).	Nzei JI et al.	—	2025	→
Effects of N-acetylcysteine after repeated exposure to ethanol in memory and neurotransmission in zebrafish.	Spilere DA et al.	—	2025	→
Effects of neonicotinoid and diamide-contaminated agricultural runoff on Lymnaea stagnalis: Insights into stress, neurotoxicity, and antioxidant response.	Rivi V et al.	—	2025	→
Effects of Nickel Bioaccumulation on Hematological, Biochemical, Immune Responses, Neuroinflammatory, Oxidative Stress Parameters, and Neurotoxicity in Rats.	El Brouzi MY et al.	—	2025	→
Exercise for brain health: From cells to circuits.	Vivar C et al.	—	2025	→
Exercise intensity determines circulating levels of Lac-Phe and other exerkines: a randomized crossover trial.	Weber D et al.	—	2025	→
Exercise modulation of gut microbiota in Alzheimer's disease: pathophysiological mechanisms and therapeutic perspectives.	Leng SY et al.	—	2025	→
Exploration of the potential neurotransmitter or neuromodulator-like properties of harmine: evidence from synthesis to synaptic modulation.	Xie Z et al.	—	2025	→
Exploring Alzheimer's disease treatment: Established therapies and novel strategies for future care.	Soni U et al.	—	2025	→
Exploring cannabinoid modulation on autophagy mechanisms in Alzheimer's disease: a review.	Ntsapi C et al.	—	2025	→
Fibre & fermented foods: differential effects on the microbiota-gut-brain axis.	Schneider E et al.	—	2025	→
Fighting Alzheimer's naturally: Peptides as multitarget drug leads.	Spinelli R et al.	—	2025	→
Frontal noradrenergic and cholinergic transients exhibit distinct spatiotemporal dynamics during competitive decision-making.	Wang H et al.	—	2025	→
Global and local nature of cortical slow waves.	Alegre-Cortés J et al.	—	2025	→
Gyral peak variations between HCP and CHCP: functional and structural implications.	Cao G et al.	—	2025	→
Human induced pluripotent stem cell-derived neurons and coculture conditions regulate the adipogenic differentiation and functionality of human adipose stromal/stem cells.	Saarimaa S et al.	—	2025	→
Hypertension Induces Cognitive Impairment and Alterations of Acetylcholine Receptor mRNA Expression in the Hippocampus and Cortex of Mice.	Liu J et al.	—	2025	→
Immunohistochemical Evaluation of Acetylcholinesterase-Positive Neurons in the Brain Cortex of Rats After Administration of Rebaudioside A.	Rycerz K et al.	—	2025	→
Influence of the Cholinergic System on the Pathogenesis of Glioblastoma: Impact of the Neutrophil Granulocytes.	Infante Cruz A et al.	—	2025	→
Inhibition of Muscle-Specific Protein Kinase (MuSK) Releases Organophosphate-Aged Acetylcholinesterase (AChE) from C2C12 Cells.	Moncada-Restrepo M et al.	—	2025	→
Innovative approaches in acetylcholinesterase inhibition: a pathway to effective Alzheimer's disease treatment.	Arora P et al.	—	2025	→
Intramuscular injection of therapeutic botulinum toxin facilitates blood coagulation in experimental aging mice.	Ravichandran S et al.	—	2025	→
Investigating Hippocampal Lateralization: Effects of Nickel on Neurobiological, AchE Activity, and Neurobehavioral Changes in the Wistar Rats.	El Brouzi MY et al.	—	2025	→
Involvement of muscarinic acetylcholine receptor-mediated cholinergic neurotransmission in TMS-EEG responses.	Song Y et al.	—	2025	→
Ion coupling and inhibitory mechanisms of the human presynaptic high-affinity choline transporter CHT1.	Qiu Y et al.	—	2025	→
IUPHAR review: Moving beyond dopamine-based therapeutic strategies for schizophrenia.	Moran PM et al.	—	2025	→
Ketamine for Depression, but at What Cost? A Review of Ketamine's Neurotoxic Effects From Preclinical and Human Studies.	Li SW et al.	—	2025	→
Light-mediated activation/deactivation control and in vitro ADME-Tox profiling of a donepezil-like Dual AChE/MAO-B Inhibitor.	Poggialini F et al.	—	2025	→
Liquid/liquid junction microelectrodes for monitoring cholinergic transmitter in live mice brain in vivo.	Xu P et al.	—	2025	→
Long COVID - a critical disruption of cholinergic neurotransmission?	Leitzke M et al.	—	2025	→
Mapping the neural and molecular basis underlying fatigue in Parkinson's disease.	Yang F et al.	—	2025	→
Modulation of neural activity and gene expression by arecoline.	Li X et al.	—	2025	→
Modulation of speed-dependent acetylcholine release in the hippocampus by spatial task engagement.	Xuan F et al.	—	2025	→
Modulatory Neurotransmitter Genotypes Shape Dynamic Functional Connectome Reconfigurations.	Jun S et al.	—	2025	→
Multi-target-directed therapeutic strategies for Alzheimer's disease: controlling amyloid-β aggregation, metal ion homeostasis, and enzyme inhibition.	Yoo J et al.	—	2025	→
Muscarinic Receptor Antagonism and TRPM3 Activation as Stimulators of Mitochondrial Function and Axonal Repair in Diabetic Sensorimotor Polyneuropathy.	Chauhan S et al.	—	2025	→
Neurochemical heterogeneity of ChAT-immunoreactive neurons in the basal forebrain cholinergic nuclei and striatum in reference to CGRP, CCK, and calcium-binding proteins.	Meher MM et al.	—	2025	→
Neuromodulatory Effects of Arecoline on Anxiety-like Behavior in Mice Exposed to Chronic Unpredictable Mild Stress.	Zhang X et al.	—	2025	→
Neuromodulatory signaling contributing to the encoding of aversion.	Wu CH et al.	—	2025	→
Neuronal and Glial α7 Nicotinic Acetylcholine Receptors: Role in Alzheimer's Disease Pathophysiology.	Rennie K	—	2025	→
Neuroprotective nutrients in pregnancy and infant brain function.	Christifano DN et al.	—	2025	→
Neuroregulation during Bone Formation and Regeneration: Mechanisms and Strategies.	Zhao X et al.	—	2025	→
Neurotoxicity and Potential Mechanisms of Exposure to Per- and Polyfluoroalkyl Substances (PFASs).	Song Y et al.	—	2025	→
Neurotransmitter analysis using liquid chromatography-electrochemical detection in the 21st century: Critical review from an analytical chemistry perspective.	Orzeł J et al.	—	2025	→
Neurotransmitter modulation of human facial emotion recognition.	Vlazaki M et al.	—	2025	→
Neurotransmitter modulation of sleep-wake States: From molecular mechanisms to therapeutic potential.	Ye X et al.	—	2025	→
Neurotransmitters in Neural Circuits and Neurological Diseases.	Gholami A et al.	—	2025	→
Neurotransmitters in tumors: chemical cross-talk shaping tumor progression.	Chen W et al.	—	2025	→
Nicotinic acetylcholine receptors in the brain.	Barrantes FJ	—	2025	→
Nicotinic Receptors in the Medial Habenula to Interpeduncular Nucleus Pathway: Modulators of Reward, Aversion and Emotion.	Ciscato M et al.	—	2025	→
Noradrenaline and acetylcholine shape functional connectivity organization of NREM substages: An empirical and simulation study.	Lehue F et al.	—	2025	→
Novel Transgenic Zebrafish Lines to Study the CHRNA3-B4-A5 Gene Cluster.	Hua Y et al.	—	2025	→
Optogenetic neuromuscular actuation of a miniature electronic biohybrid robot.	Min H et al.	—	2025	→
Oxidative Stress-Mediated Neuroinflammation in the Pathophysiology of Schizophrenia.	Trubalski M et al.	—	2025	→
Phase synchrony between prefrontal noradrenergic and cholinergic signals indexes inhibitory control.	Liu YA et al.	—	2025	→
Prenatal Exposure to Imidacloprid Affects Cognition and Anxiety-Related Behaviors in Male and Female CD-1 Mice.	Lee C et al.	—	2025	→
Pro-Inflammatory Protein PSCA Is Upregulated in Neurological Diseases and Targets β2-Subunit-Containing nAChRs.	Shulepko MA et al.	—	2025	→
Protective effect of cholecalciferol against cobalt-induced neurotoxicity in rats: ZO-1/iFABP, ChAT/AchE and antioxidant pathways as potential therapeutic targets.	Akinrinde AS et al.	—	2025	→
Psilocybin as Transformative Fast-Acting Antidepressant: Pharmacological Properties and Molecular Mechanisms.	Adebo M et al.	—	2025	→
Radiation dosimetry and fasting-dependent hepatobiliary clearance of the VAChT-specific PET radioligand <sup>18</sup>F-VAT in humans.	Norris SA et al.	—	2025	→
Rapid Changes in Cholinergic Signaling, Myelination, and Thyroid Signaling Pathway Gene Expression in Amygdala Subnuclei in Response to Social Status Maintenance and Reorganization.	Milewski TM et al.	—	2025	→
REM sleep prefrontal ripple chains mediate distinct cortical-hippocampal reactivation patterns compared to NREM ripples	Shin JD et al.	—	2025	—
Role of the cholinergic system in the psychopathology and treatment of schizophrenia: a protocol for a scoping review.	Haczkiewicz M et al.	—	2025	→
Septo-subicular cholinergic circuit promotes seizure development via astrocytic inflammation.	Wang Y et al.	—	2025	→
Serum metabolites and inflammation predict brain functional connectivity changes in Obsessive-Compulsive disorder.	Chen G et al.	—	2025	→
Signs of Alzheimer's Disease: Tied to Aging.	Chen J et al.	—	2025	→
Single-cell profiling of H3K4me1-H3K27me3 revealed bivalent regulation of abnormal neuronal development caused by prenatal e-cigarette vaporing.	Chen Z et al.	—	2025	→
Social hierarchy modulates cognitive flexibility through basal forebrain-prefrontal cholinergic projections.	Wu J et al.	—	2025	→
Sunflower Oil Fortified with Vitamins D and A and Sunflower Lecithin Ameliorated Scopolamine-Induced Cognitive Dysfunction in Mice and Exploration of the Underlying Protective Pathways.	Tang X et al.	—	2025	→
Synchrony of neuromodulatory systems during NREM sleep.	Teng S et al.	—	2025	→
Synergistic mechanisms of medullary cholinergic-serotonergic pathway interactions in regulating neuronal excitability and locomotor activities.	Cheng Y et al.	—	2025	→
Systematic review: Effects of cholinergic signaling on cognition in human pharmacological studies.	Dan YR et al.	—	2025	→
Targeting Neuronal Alpha7 Nicotinic Acetylcholine Receptor Upregulation in Age-Related Neurological Disorders.	Abraham SM et al.	—	2025	→
The Central Cholinergic Synapse: A Primer.	Klein J	—	2025	→
The cholinergic basal forebrain and its role in neurodegeneration.	Cykowski MD et al.	—	2025	→
The Duality of Astrocyte Neuromodulation: Astrocytes Sense Neuromodulators and Are Neuromodulators.	Lines J et al.	—	2025	→
The effect of acetylcholinesterase inhibitor rivastigmine in pentylenetetrazole-induced kindling model of epilepsy in rats.	Ak ET et al.	—	2025	→
The endogenous cholinergic system overwhelmingly predominates over the exogenous system in regulating ventricular bioelectrical homeostasis.	Xie D et al.	—	2025	→
The influence of sleep on human taste function and perception: A systematic review.	Tucker RM et al.	—	2025	→
The influence of stress and social defeat on neurobiological reinforcement mechanisms across reward to withdrawal in nicotine addiction.	Shankar K et al.	—	2025	→
The involvement of the cholinergic system in Parkinson disease.	Pasquini J et al.	—	2025	→
The psychobiotic revolution: comprehending the optimistic role of gut microbiota on gut-brain axis during neurological and Gastrointestinal (GI) disorders.	Mohiuddin M et al.	—	2025	→
The Regulatory Roles of REST in the Synaptic Development, Function and Related Neurological Disorders.	Lim CT et al.	—	2025	→
The relationship between prenatal perfluorine and polyfluoroalkyl substances (PFAS) exposure and infant neurodevelopment: Modifying effects of DHA revised.	Jiang TT et al.	—	2025	→
The rise of dehydrated ginsenosides: phytochemistry and pharmacology.	Wang KH et al.	—	2025	→
The role of acetylcholine and its receptors in tumor immune regulation: mechanisms and potential therapeutic targets.	Zhang C et al.	—	2025	→
The Role of Acetylcholinesterase Enzyme Inhibitor Rivastigmine on Spike-Wave Discharges, Learning-Memory, Anxiety, and TRPV1 Channel Expression in Genetic Absence Epileptic WAG/Rij Rats.	Türkdönmez Ak E et al.	—	2025	→
Three-factor learning in spiking neural networks: An overview of methods and trends from a machine learning perspective.	Mazurek S et al.	—	2025	→
Transdermal delivery of resveratrol loaded solid lipid nanoparticle as a microneedle patch: a novel approach for the treatment of Parkinson's disease.	Bandiwadekar A et al.	—	2025	→
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Trans-synaptic modulation of cholinergic circuits tunes opioid reinforcement.	Zucca S et al.	—	2025	→
Uncertainty estimation with prediction-error circuits.	Hertäg L et al.	—	2025	→
Unraveling the peripheral nervous System's role in tumor: A Double-edged Sword.	Wang YH et al.	—	2025	→
Unravelling the multifaceted actions of neurosteroids: Machine learning and in vitro screening for novel target discovery.	Kumar A et al.	—	2025	→
Unveiling the substantial role of rutin in the management of drug-induced nephropathy using network pharmacology and molecular docking.	Thakur P et al.	—	2025	→
Visual hallucinations in Parkinson's disease: spotlight on central cholinergic dysfunction.	Ignatavicius A et al.	—	2025	→
Water extract of <i>Humulus japonicus</i> improves age‑related cognitive decline by inhibiting acetylcholinesterase activity and the acetylcholine signaling pathway.	Kim JE et al.	—	2025	→
α4β2<sup>*</sup> nicotinic acetylcholine receptors drive human temporal glutamate/GABA balance toward inhibition.	Martinello K et al.	—	2025	→
Accelerated neurodegeneration of basal forebrain cholinergic neurons in HIV-1 gp120 transgenic mice: Critical role of the p75 neurotrophin receptor.	Speidell A et al.	—	2024	→
Acetylcholine and metacognition during sleep.	Gott JA et al.	—	2024	→
Acetylcholine modulates the precision of prediction error in the auditory cortex.	Pérez-González D et al.	—	2024	→
Acetylcholine muscarinic M1 receptors in the rodent prefrontal cortex modulate cognitive abilities to establish social hierarchy.	Chen WJ et al.	—	2024	→
A Little "Re-Cognition" Goes a Long Way for Pro-Cognitive Therapeutics in Alcohol Studies.	Salling MC et al.	—	2024	→
Alpha5 nicotine acetylcholine receptor subunit promotes intrahepatic cholangiocarcinoma metastasis.	Fu Y et al.	—	2024	→
Altered resting-state brain oscillation and the associated cognitive impairments in late-life depression with different depressive severity: An EEG power spectrum and functional connectivity study.	Zeng Y et al.	—	2024	→
Alzheimer's disease and epilepsy: Research hotspots for comorbidity in the era of global aging.	Zhou X et al.	—	2024	→
Analyzing Fusion Pore Dynamics and Counting the Number of Acetylcholine Molecules Released by Exocytosis.	Wang Y et al.	—	2024	→
A non-adaptationist hypothesis of play behaviour.	Lewis A	—	2024	→
An updated review of the pharmacological effects and potential mechanisms of hederagenin and its derivatives.	Zhang H et al.	—	2024	→
Basal forebrain cholinergic activity is necessary for upward firing rate homeostasis in the rodent visual cortex.	Bottorff J et al.	—	2024	→
Brain-state-dependent constraints on claustrocortical communication and function.	Marriott BA et al.	—	2024	→
Brain-to-heart cholinergic synapse-calcium signaling mediates ischemic stroke-induced atrial fibrillation.	Liang Y et al.	—	2024	→
Centralizing the Knowledge and Interpretation of Pain in Chemotherapy-Induced Peripheral Neuropathy: A Paradigm Shift towards Brain-Centric Approaches.	Cunha M et al.	—	2024	→
Choline kinase alpha genotype is related to hippocampal brain volume and cognition in postmenopausal women.	Myers AJ et al.	—	2024	→
Cholinergic Basal Forebrain Connectivity to the Basolateral Amygdala Modulates Food Intake.	Ortiz-Guzman J et al.	—	2024	→
Cholinergic macrophages promote the resolution of peritoneal inflammation.	Luo S et al.	—	2024	→
Cholinergic modulation supports dynamic switching of resting state networks through selective DMN suppression.	Sanda P et al.	—	2024	→
Cholinergic Neuromodulation of Prefrontal Attractor Dynamics Controls Performance in Spatial Working Memory.	Mahrach A et al.	—	2024	→
Cholinergic-related pupil activity reflects level of emotionality during motor performance.	Vidal M et al.	—	2024	→
Comparative Physiology and Morphology of BLA-Projecting NBM/SI Cholinergic Neurons in Mouse and Macaque.	Luo F et al.	—	2024	→
Comparative review of the brain development in Acomys cahirinus.	Merkulyeva N	—	2024	→
Current Findings and Potential Mechanisms of KarXT (Xanomeline-Trospium) in Schizophrenia Treatment.	Azargoonjahromi A	—	2024	→
Deep Brain Stimulation Mechanisms in Parkinson's Disease: Immediate and Long-Term Effects.	Pei H et al.	—	2024	→
Diethyl nitrosamine-induces neurobehavioral deficit, oxido-nitrosative stress in rats' brain: a neuroprotective role of diphenyl diselenide.	Owumi S et al.	—	2024	→
Distinct eLPB<sup>ChAT</sup> projections for methamphetamine withdrawal anxiety and primed reinstatement of conditioned place preference.	Chen W et al.	—	2024	→
Distributed and dynamical communication: a mechanism for flexible cortico-cortical interactions and its functional roles in visual attention.	Ni S et al.	—	2024	→
Environmental levels of azoxystrobin disturb male zebrafish behavior: Possible roles of oxidative stress, cholinergic system, and dopaminergic system.	Guo X et al.	—	2024	→
Exploring the multifaceted potential of (R)-ketamine beyond antidepressant applications.	Zhang S et al.	—	2024	→
Exposing the latent phenotype of Gulf War Illness: examination of the mechanistic mediators of cognitive dysfunction.	Burzynski HE et al.	—	2024	→
Fast and slow: Recording neuromodulator dynamics across both transient and chronic time scales.	Ma P et al.	—	2024	→
Flexible Acetylcholine Neural Probe with a Hydrophobic Laser-Induced Graphene Electrode and a Fluorous-Phase Sensing Membrane.	Amirghasemi F et al.	—	2024	→
From Synaptic Physiology to Synaptic Pathology: The Enigma of α-Synuclein.	Nordengen K et al.	—	2024	→
Genetic Association Study of Acetylcholinesterase (<i>ACHE</i>) and Butyrylcholinesterase (<i>BCHE</i>) Variants in Sudden Infant Death Syndrome (SIDS).	Qu D et al.	—	2024	→
Gut microbiota metabolites: potential therapeutic targets for Alzheimer's disease?	Zhang S et al.	—	2024	→
High-Throughput Screening to Advance In Vitro Toxicology: Accomplishments, Challenges, and Future Directions.	Lynch C et al.	—	2024	→
Hippocampus encoding memory engrams as stable heteroclinic network.	Yang L et al.	—	2024	→
Huperzine A suppresses absence seizures in the genetic absence epilepsy rat from Strasbourg (GAERS) model of genetic generalized epilepsy with absence seizures.	Casillas-Espinosa PM et al.	—	2024	→
Impact of Sublethal Insecticides Exposure on <i>Vespa magnifica</i>: Insights from Physiological and Transcriptomic Analyses.	Hu Q et al.	—	2024	→
Improving Neurological Health in Aging Via Neuroplasticity-Based Computerized Exercise: Protocol for a Randomized Controlled Trial.	Attarha M et al.	—	2024	→
Inhibiting cholinergic signalling in the cerebellar interpositus nucleus impairs motor behaviour.	Pickford J et al.	—	2024	→
Investigating the selective attention, attentional bias and smoking among Turkish University students: A cross-sectional study.	Taskan HS et al.	—	2024	→
Key targets of signal transduction neural mechanisms in acupuncture treatment of cardiovascular diseases: Hypothalamus and autonomic nervous system.	Zhou X et al.	—	2024	→
Latest advances in mechanisms of epileptic activity in Alzheimer's disease and dementia with Lewy Bodies.	Vicente M et al.	—	2024	→
Long-term exposure to ionic liquid [C<sub>8</sub>mim]Br induces the potential risk of anxiety and memory deterioration through disturbing neurotransmitter systems.	Wang H et al.	—	2024	→
Mapping seasonal migration in a songbird hybrid zone -- heritability, genetic correlations, and genomic patterns linked to speciation.	Justen HC et al.	—	2024	→
Maternal exposure to glyphosate increased the risk of adverse neurodevelopmental outcomes in rodent offspring: A systematic review.	Marins K et al.	—	2024	→
Mechanisms of microRNA-132 in central neurodegenerative diseases: A comprehensive review.	Mu C et al.	—	2024	→
Mechanisms of vagus nerve stimulation for the treatment of neurodevelopmental disorders: a focus on microglia and neuroinflammation.	Gargus M et al.	—	2024	→
MFSD7c functions as a transporter of choline at the blood-brain barrier.	Nguyen XTA et al.	—	2024	→
Microbiota-Gut-Brain Axis Dysregulation in Alzheimer's Disease: Multi-Pathway Effects and Therapeutic Potential.	Qu L et al.	—	2024	→
Microbiota-gut-brain axis in health and neurological disease: Interactions between gut microbiota and the nervous system.	He Y et al.	—	2024	→
Modafinil, an atypical CNS stimulant?	Hersey M et al.	—	2024	→
Modulation of cortical representations of sensory and contextual information underlies aversive associative learning.	Dai J et al.	—	2024	→
Morphometric brain organization across the human lifespan reveals increased dispersion linked to cognitive performance.	Li J et al.	—	2024	→
M<sub>1</sub>/M<sub>4</sub> receptors as potential therapeutic treatments for schizophrenia: A comprehensive study.	Fu L et al.	—	2024	→
Multimodal neuroimaging-based prediction of Parkinson's disease with mild cognitive impairment using machine learning technique.	Zhu Y et al.	—	2024	→
Multiomics Evaluation of Human iPSCs and iPSC-Derived Neurons.	Lee GB et al.	—	2024	→
Multiple cholinergic receptor subtypes coordinate dual modulation of acetylcholine on anterior and posterior paraventricular thalamic neurons.	Ye Q et al.	—	2024	→
Muscarinic Modulation of Network Excitability and Short-Term Dynamics in the Dorsal and Ventral Hippocampus.	Tsotsokou G et al.	—	2024	→
Natural Products and Their Neuroprotective Effects in Degenerative Brain Diseases: A Comprehensive Review.	Lim DW et al.	—	2024	→
Neuroanatomical Substrates of Circuit-Specific Cholinergic Modulation across the Primate Anterior Cingulate Cortex.	Tsolias A et al.	—	2024	→
Neuroimmune communication of the cholinergic system in gut inflammation and autoimmunity.	Halder N et al.	—	2024	→
Neurotransmitter acetylcholine mediates the mummification of <i>Ophiocordyceps sinensis</i>-infected <i>Thitarodes xiaojinensis</i> larvae.	Chai W et al.	—	2024	→
Ngfr<sup>+</sup> cholinergic projection from SI/nBM to mPFC selectively regulates temporal order recognition memory.	Mei F et al.	—	2024	→
Nicotinic and Muscarinic Acetylcholine Receptor Agonists Counteract Cognitive Impairment in a Rat Model of Doxorubicin-Induced Chemobrain via Attenuation of Multiple Programmed Cell Death Pathways.	Ongnok B et al.	—	2024	→
Obesogenic potentials of environmental artificial sweeteners with disturbances on both lipid metabolism and neural responses.	Jiang L et al.	—	2024	→
Olfactory deficits in aging and Alzheimer's-spotlight on inhibitory interneurons.	Elhabbari K et al.	—	2024	→
On the genesis and unique functions of zinc neuromodulation.	Bizup B et al.	—	2024	→
Outer Membrane Vesicles Released from Garlic Exosome-like Nanoparticles (GaELNs) Train Gut Bacteria that Reverses Type 2 Diabetes via the Gut-Brain Axis.	Sundaram K et al.	—	2024	→
Perirhinal cortex learns a predictive map of the task environment.	Lee DG et al.	—	2024	→
PET imaging of M4 muscarinic acetylcholine receptors in rhesus macaques using [<sup>11</sup>C]MK-6884: Quantification with kinetic modeling and receptor occupancy by CVL-231 (emraclidine), a novel positive allosteric modulator.	Belov V et al.	—	2024	→
Pharmacological Treatments for Methamphetamine Use Disorder: Current Status and Future Targets.	Yates JR	—	2024	→
Psilocybin and the glutamatergic pathway: implications for the treatment of neuropsychiatric diseases.	Szpręgiel I et al.	—	2024	→
Psychosis as a disorder of muscarinic signalling: psychopathology and pharmacology.	McCutcheon RA et al.	—	2024	→
Recent advances in stimuli-responsive controlled release systems for neuromodulation.	Shi J et al.	—	2024	→
Septohippocampal cholinergic system at the intersection of stress and cognition: Current trends and translational implications.	Kniffin A et al.	—	2024	→
Slow and fast cortical cholinergic arousal is reduced in a mouse model of focal seizures with impaired consciousness.	Sieu LA et al.	—	2024	→
Stimulation of the muscarinic receptor M4 regulates neural precursor cell proliferation and promotes adult hippocampal neurogenesis.	Madrid LI et al.	—	2024	→
Structural mechanisms of human sodium-coupled high-affinity choline transporter CHT1.	Xue J et al.	—	2024	→
Succinimide Derivatives as Acetylcholinesterase Inhibitors-In Silico and In Vitro Studies.	Grodner B et al.	—	2024	→
The cancer-immune dialogue in the context of stress.	Ma Y et al.	—	2024	→
The integrated stress response pathway and neuromodulator signaling in the brain: lessons learned from dystonia.	Calakos N et al.	—	2024	→
The looming threat of profenofos organophosphate and microbes in action for their sustainable degradation.	Raj A et al.	—	2024	→
The Microbiota-Gut-Brain Axis and Neurological Disorders: A Comprehensive Review.	Nakhal MM et al.	—	2024	→
Therapeutic potential of clinically proven natural products in the management of dementia.	Ansari F et al.	—	2024	→
Tobacco use disorder in patients with other mental disorders: a dual disorder perspective from clinical neuroscience.	Szerman N et al.	—	2024	→
Transcriptomic analysis of sexually dimorphic cypris larvae of the rhizocephalan barnacle Peltogasterella gracilis.	Kajimoto A et al.	—	2024	→
Transport mechanism of presynaptic high-affinity choline uptake by CHT1.	Qiu Y et al.	—	2024	→
Tropisetron, an Antiemetic Drug, Exerts an Anti-Epileptic Effect Through the Activation of α7nAChRs in a Rat Model of Temporal Lobe Epilepsy.	Qian X et al.	—	2024	→
Unresponsiveness induced by sevoflurane and propofol is associated with reduced basal forebrain cholinergic nuclei functional connectivity in humans, <i>a pilot exploratory study</i>.	Zimmermann J et al.	—	2024	→
Vasant Kusumakar Rasa Ameliorates Diabetic Encephalopathy by Reducing Oxidative Stress and Neuroinflammation and Improving Neurotransmitter Levels in Experimental Animals.	Singh AD et al.	—	2024	→
Vilazodone exposure during pregnancy: Effects on embryo-fetal development, pregnancy outcomes and fetal neurotoxicity by BDNF/Bax-Bcl2/5-HT mediated mechanisms.	Agrawal P et al.	—	2024	→
α7 nicotinic acetylcholine receptor in memory processing.	Pastor V et al.	—	2024	→
α7 nicotinic acetylcholine receptors induce long-term synaptic enhancement in the dorsal but not ventral hippocampus.	Tsotsokou G et al.	—	2024	→
Accumbens cholinergic interneurons dynamically promote dopamine release and enable motivation.	Mohebi A et al.	—	2023	→
Acetylcholine facilitates localized synaptic potentiation and location specific feature binding.	Yang Y et al.	—	2023	→
Acetylcholine Inhibits Spontaneous Firing Activity of Terminal Nerve GnRH Neurons in Medaka.	Tanaka A et al.	—	2023	→
A cholinergic circuit that relieves pain despite opioid tolerance.	Sullere S et al.	—	2023	→
Action of the Purinergic and Cholinergic Anti-inflammatory Pathways on Oxidative Stress in Patients with Alzheimer's Disease in the Context of the COVID-19 Pandemic.	Simões JLB et al.	—	2023	→
Adaptive control of synaptic plasticity integrates micro- and macroscopic network function.	Scott DN et al.	—	2023	→
Advances in the study of cholinergic circuits in the central nervous system.	He G et al.	—	2023	→
Amine-recognizing domain in diverse receptors from bacteria and archaea evolved from the universal amino acid sensor.	Cerna-Vargas JP et al.	—	2023	→
An exploratory study of brain temperature and choline abnormalities in temporal lobe epilepsy patients with depressive symptoms.	Oates M et al.	—	2023	→
Apoptosis in the neuroprotective effect of α7 nicotinic receptor in neurodegenerative models.	Mugayar AA et al.	—	2023	→
Arsenic Impairs Differentiation of Human Induced Pluripotent Stem Cells into Cholinergic Motor Neurons.	Perego MC et al.	—	2023	→
A systematic review of the biological mediators of fat taste and smell.	Jaime-Lara RB et al.	—	2023	→
Autogenous cerebral processes: an invitation to look at the brain from inside out.	Maldonado PE et al.	—	2023	→
Basal forebrain cholinergic signalling: development, connectivity and roles in cognition.	Ananth MR et al.	—	2023	→
Basal forebrain functional connectivity as a mediator of associations between cardiorespiratory fitness and cognition in healthy older women.	Won J et al.	—	2023	→
Biosynthesized Selenium Nanoparticles Using Epigallocatechin Gallate Protect against Pentylenetetrazole-Induced Acute Epileptic Seizures in Mice via Antioxidative, Anti-Inflammatory, and Anti-Apoptotic Activities.	Alrashdi BM et al.	—	2023	→
Biphasic Cholinergic Modulation of Reverberatory Activity in Neuronal Networks.	Li XW et al.	—	2023	→
Bulbar projecting subcortical GABAergic neurons send collateral branches extensively and selectively to primary olfactory cortical regions.	Hook C et al.	—	2023	→
Calcium Imaging Characterize the Neurobiological Effect of Terahertz Radiation in Zebrafish Larvae.	Song X et al.	—	2023	→
Canagliflozin alleviates valproic acid-induced autism in rat pups: Role of PTEN/PDK/PPAR-γ signaling pathways.	Elgamal MA et al.	—	2023	→
Characterization of three cholinergic inputs to the cochlear nucleus.	Beebe NL et al.	—	2023	→
Choline-acetyltransferase (ChAT) and acetylcholinesterase (AChE) in the human infant dorsal motor nucleus of the Vagus (DMNV), and alterations according to sudden infant death syndrome (SIDS) category.	Joda M et al.	—	2023	→
Choline and Fish Oil Can Improve Memory of Mice through Increasing Brain DHA Level.	Li J et al.	—	2023	→
Cholinergic and noradrenergic axonal activity contains a behavioral-state signal that is coordinated across the dorsal cortex.	Collins L et al.	—	2023	→
Cholinergic deficiency in the cholinergic system as a pathogenetic link in the formation of various syndromes in COVID-19.	Lysenkov SP et al.	—	2023	→
Cholinergic-estrogen interaction is associated with the effect of education on attenuating cognitive sex differences in a Thai healthy population.	Chen C et al.	—	2023	→
Cholinergic Functioning, Cognition, and Anticholinergic Medication Burden in Schizophrenia.	Joshi YB	—	2023	→
Cholinergic system adaptations are associated with cognitive function in people recently abstinent from smoking: a (-)-[<sup>18</sup>F]flubatine PET study.	Calakos KC et al.	—	2023	→
Cognitive impairment in patients with heart failure: molecular mechanism and therapy.	Wu Y et al.	—	2023	→
Comprehensive Analysis of Titanium Oxide Nanoparticle Size and Surface Properties on Neuronal PC-12 Cells: Unraveling Cytotoxicity, Dopaminergic Gene Expression, and Acetylcholinesterase Inhibition.	Suthar JK et al.	—	2023	→
Current Status of Alzheimer's Disease and Pathological Mechanisms Investigating the Therapeutic Molecular Targets.	Bagga S et al.	—	2023	→
Design, synthesis and evaluation of novel 2-phenyl-3-(1H-pyrazol-4-yl)pyridine positive allosteric modulators for the M<sub>4</sub> mAChR.	Jörg M et al.	—	2023	→
Discoveries and future significance of research into amyloid-beta/α7-containing nicotinic acetylcholine receptor (nAChR) interactions.	Whiteaker P et al.	—	2023	→
Donepezil alone and combined with intensive language-action therapy on depression and apathy in chronic post-stroke aphasia: A feasibility study.	Berthier ML et al.	—	2023	→
Dysbiosis and Alzheimer's disease: role of probiotics, prebiotics and synbiotics.	Thakkar A et al.	—	2023	→
Exploring Cholinergic Compounds for Peripheral Neuropathic Pain Management: A Comprehensive Scoping Review of Rodent Model Studies.	Montigné E et al.	—	2023	→
Exploring the Role of Neurotransmitters in Multiple Sclerosis: An Expanded Review.	Akyuz E et al.	—	2023	→
Extract of <i>Aster koraiensis</i> Nakai Leaf Ameliorates Memory Dysfunction via Anti-inflammatory Action.	Lee SE et al.	—	2023	→
Frequency-dependent centrifugal modulation of the activity of different classes of mitral and tufted cells in olfactory bulb.	Zhou FW et al.	—	2023	→
Functional characterization of three G protein-coupled acetylcholine receptors in parasitic nematode Trichinella spiralis.	Nìng C et al.	—	2023	→
Glaucoma: Biological Mechanism and its Clinical Translation.	Durán-Cristiano SC	—	2023	→
Graphene-Related Nanomaterials for Biomedical Applications.	Lazăr AI et al.	—	2023	→
Gut-Brain Axis and Neurological Disorders-How Microbiomes Affect our Mental Health.	Bhatia NY et al.	—	2023	→
Hallmarks of peripheral nerve function in bone regeneration.	Tao R et al.	—	2023	→
Hepatic phosphatidylcholine catabolism driven by PNPLA7 and PNPLA8 supplies endogenous choline to replenish the methionine cycle with methyl groups.	Hirabayashi T et al.	—	2023	→
Hexaconazole exposure disrupt acetylcholinesterase, leading to mental illness.	Ali A et al.	—	2023	→
Hibiscus sabdariffa (Roselle) calyx: a systematic and meta-analytic review of memory-enhancing, anti-neuroinflammatory and antioxidative activities.	Olasehinde TA et al.	—	2023	→
High expression of NF-κB inducing kinase in the bulge region of hair follicle induces tumor.	Duan W et al.	—	2023	→
Household based-pyrethroids on adult zebrafish (Danio rerio) exert behavioral and cholinergic changes in different brain regions.	Tamagno WA et al.	—	2023	→
How can I measure brain acetylcholine levels in vivo? Advantages and caveats of commonly used approaches.	Mineur YS et al.	—	2023	→
Hyaluronic Acid Conjugated with 17β-Estradiol Effectively Alleviates Estropause-Induced Cognitive Deficits in Rats.	Chen MH et al.	—	2023	→
Impact of Anticholinergic Medications on Speech Perception Performance after Cochlear Implantation.	Layfield E et al.	—	2023	→
Inclusion of frailty improved performance of delirium prediction for elderly patients in the cardiac intensive care unit (D-FRAIL): A prospective derivation and external validation study.	Guo R et al.	—	2023	→
Individual and interactive biochemical profile damages in Labeo rohita (Cyprinidae) by imidacloprid and clothianidin.	Gajula SK et al.	—	2023	→
Investigation on Novel <i>E/Z</i> 2-Benzylideneindan-1-One-Based Photoswitches with AChE and MAO-B Dual Inhibitory Activity.	Paolino M et al.	—	2023	→
Is the post-COVID-19 syndrome a severe impairment of acetylcholine-orchestrated neuromodulation that responds to nicotine administration?	Leitzke M	—	2023	→
Label free impedance based acetylcholinesterase enzymatic biosensors for the detection of acetylcholine.	Chen J et al.	—	2023	→
Limbic System Response to Psilocybin and Ketamine Administration in Rats: A Neurochemical and Behavioral Study.	Wojtas A et al.	—	2023	→
M1 acetylcholine receptors in somatostatin interneurons contribute to GABAergic and glutamatergic plasticity in the mPFC and antidepressant-like responses.	Fogaça MV et al.	—	2023	→
Magnetic vagus nerve stimulation alleviates myocardial ischemia-reperfusion injury by the inhibition of pyroptosis through the M<sub>2</sub>AChR/OGDHL/ROS axis in rats.	Lu Y et al.	—	2023	→
Mechanisms of Organophosphate Toxicity and the Role of Acetylcholinesterase Inhibition.	Aroniadou-Anderjaska V et al.	—	2023	→
Metabolomic insights into neurological effects of BDE-47 exposure in the sea cucumber Apostichopus japonicus.	Ding K et al.	—	2023	→
Microbiome and spatially resolved metabolomics analysis reveal the anticancer role of gut Akkermansia muciniphila by crosstalk with intratumoral microbiota and reprogramming tumoral metabolism in mice.	Zhu Z et al.	—	2023	→
Mitigation of nicotine-induced developmental effects by 24-epibrassinolide in zebrafish.	Pereira F et al.	—	2023	→
Muscarinic antagonists impair multiple aspects of operant discrimination learning and performance.	Yousuf H et al.	—	2023	→
Muscarinic receptor activation overrides boundary conditions on memory updating in a calcium/calmodulin-dependent manner.	Wideman CE et al.	—	2023	→
Neuroimaging genetics approaches to identify new biomarkers for the early diagnosis of autism spectrum disorder.	Nisar S et al.	—	2023	→
Neuroprotective and Antioxidant Role of Oxotremorine-M, a Non-selective Muscarinic Acetylcholine Receptors Agonist, in a Cellular Model of Alzheimer Disease.	Nuzzo D et al.	—	2023	→
Neurotransmitters arrive to control systemic autoimmunity.	Scherlinger M et al.	—	2023	→
Neurotransmitter systems in the etiology of major neurological disorders: Emerging insights and therapeutic implications.	Nimgampalle M et al.	—	2023	→
New perspectives on the basal forebrain cholinergic system in Alzheimer's disease.	Berry AS et al.	—	2023	→
Nicotine's effect on cognition, a friend or foe?	Wang Q et al.	—	2023	→
Nicotinic and muscarinic acetylcholine receptor antagonism dose-dependently decreases sign- but not goal-tracking behavior in male rats.	Gheidi A et al.	—	2023	→
Noradrenergic and cholinergic systems take centre stage in neuropsychiatric diseases of ageing.	Orlando IF et al.	—	2023	→
Nucleus accumbens local circuit for cue-dependent aversive learning.	Belilos A et al.	—	2023	→
Organizational Principles of the Centrifugal Projections to the Olfactory Bulb.	Wang L et al.	—	2023	→
Oxidative stress, dysfunctional energy metabolism, and destabilizing neurotransmitters altered the cerebral metabolic profile in a rat model of simulated heliox saturation diving to 4.0 MPa.	Liu X et al.	—	2023	→
Perfluorononanoic Acid Induces Neurotoxicity via Synaptogenesis Signaling in Zebrafish.	Liu S et al.	—	2023	→
Plasticity in ventral pallidal cholinergic neuron-derived circuits contributes to comorbid chronic pain-like and depression-like behaviour in male mice.	Ji YW et al.	—	2023	→
Polystyrene nanoplastics in the marine mussel Mytilus galloprovincialis.	Gonçalves JM et al.	—	2023	→
Potential revival of cholinesterase inhibitors as drugs in veterinary medicine.	Žnidaršič N et al.	—	2023	→
Prenatal cyanuric acid exposure induced spatial learning impairments associated with alteration of acetylcholine-mediated neural information flow at the hippocampal CA3-CA1 synapses of male rats.	Sun W et al.	—	2023	→
Rivastigmine ameliorates botulinum-induced hippocampal damage and spatial memory impairment in male rats.	Mehri K et al.	—	2023	→
Sleep-mediated regulation of reward circuits: implications in substance use disorders.	Guo R et al.	—	2023	→
Somatostatin neurons in the central amygdala mediate anxiety by disinhibition of the central sublenticular extended amygdala.	Sun Y et al.	—	2023	→
Spectroscopic Determination of Acetylcholine (ACh): A Representative Review.	Świt P et al.	—	2023	→
Structural degeneration of the nucleus basalis of Meynert in mild cognitive impairment and Alzheimer's disease - Evidence from an MRI-based meta-analysis.	Mieling M et al.	—	2023	→
Structure and function of neocortical layer 6b.	Feldmeyer D	—	2023	→
Synthesis of phenylethanoid glycosides from acrylic esters of glucose and aryldiazonium salts via palladium-catalyzed cross-coupling reactions and evaluation of their anti-Alzheimer activity.	Narayanan AC et al.	—	2023	→
The critical role of gut-brain axis microbiome in mental disorders.	Basiji K et al.	—	2023	→
The effect of non-invasive vagus nerve stimulation on memory recall in reading: A pilot study.	Thakkar VJ et al.	—	2023	→
The effect of the calcium channel blocker nimodipine on hippocampal BDNF/Ach levels in rats with experimental cognitive impairment.	Topcu A et al.	—	2023	→
The hyperexcitability of laterodorsal tegmentum cholinergic neurons accompanies adverse behavioral and cognitive outcomes of prenatal stress.	Shabani M et al.	—	2023	→
The immunotoxicity mechanism of NH<sub>4</sub>Cl exposure to Litopenaeus vannamei based on the cerebral ganglion-eyestalk-haemocytes axis.	Tong R et al.	—	2023	→
The neurobiology and therapeutic potential of multi-targeting β-secretase, glycogen synthase kinase 3β and acetylcholinesterase in Alzheimer's disease.	Fronza MG et al.	—	2023	→
The neuroprotective and neural circuit mechanisms of acupoint stimulation for cognitive impairment.	Zhang Z et al.	—	2023	→
The Role of the Acetylcholine System in Common Respiratory Diseases and COVID-19.	Li D et al.	—	2023	→
Total choline intake and working memory performance in adults with phenylketonuria.	Schoen MS et al.	—	2023	→
Turning the Spotlight to Cholinergic Pharmacotherapy of the Human Language System.	Dávila G et al.	—	2023	→
Understanding the Gut-Brain Axis and Its Therapeutic Implications for Neurodegenerative Disorders.	Zheng Y et al.	—	2023	→
UV-aged microplastics induces neurotoxicity by affecting the neurotransmission in larval zebrafish.	Xiang C et al.	—	2023	→
Whole-brain modeling explains the context-dependent effects of cholinergic neuromodulation.	Coronel-Oliveros C et al.	—	2023	→
α7 Nicotinic acetylcholine receptor: a key receptor in the cholinergic anti-inflammatory pathway exerting an antidepressant effect.	Liu H et al.	—	2023	→
α7 nicotinic acetylcholine receptors in the medial prefrontal cortex control rewarding but not aversive memory expression in a dopamine-sensitive manner.	Pastor V et al.	—	2023	→
Δ<sup>8</sup>-THC Induces Up-Regulation of Glutamatergic Pathway Genes in Differentiated SH-SY5Y: A Transcriptomic Study.	Anchesi I et al.	—	2023	→
Adolescent nicotine administration increases nicotinic acetylcholine receptor binding and functional connectivity in specific cortico-striatal-thalamic circuits.	Keeley RJ et al.	—	2022	→
Age-related differences in the effect of chronic alcohol on cognition and the brain: a systematic review.	Kuhns L et al.	—	2022	→
Aging-Related Alterations to Persistent Firing in the Lateral Entorhinal Cortex Contribute to Deficits in Temporal Associative Memory.	Lin C et al.	—	2022	→
An Investigation of the Neurotoxic Effects of Malathion, Chlorpyrifos, and Paraquat to Different Brain Regions.	Elmorsy E et al.	—	2022	→
Antagonism of nicotinic acetycholinergic receptors by CN-105, an apoE-mimetic peptide reduces stroke-induced excitotoxicity.	Xue M et al.	—	2022	→
Antihypertensive Mechanism of Orally Administered Acetylcholine in Spontaneously Hypertensive Rats.	Yamaguchi S et al.	—	2022	→
A Revisit to Etiopathogenesis and Therapeutic Strategies in Alzheimer's Disease.	Kumar M et al.	—	2022	→
A selective degeneration of cholinergic neurons mediated by NRADD in an Alzheimer's disease mouse model.	Li L et al.	—	2022	→
Association Between the Cholinesterase Inhibitor Donepezil and the Cholinergic Precursor Choline Alphoscerate in the Treatment of Depression in Patients with Alzheimer's Disease.	Carotenuto A et al.	—	2022	→
Associations of the Lipidome with Ageing, Cognitive Decline and Exercise Behaviours.	Kadyrov M et al.	—	2022	→
Behavioral genetics of alcohol's effects in three zebrafish (Danio rerio) populations.	Agues-Barbosa T et al.	—	2022	→
Bioavailability of Hesperidin and Its Aglycone Hesperetin-Compounds Found in Citrus Fruits as a Parameter Conditioning the Pro-Health Potential (Neuroprotective and Antidiabetic Activity)-Mini-Review.	Wdowiak K et al.	—	2022	→
Brain systems in cocaine abstinence-induced anxiety-like behavior in rodents: A review.	Barbee BR et al.	—	2022	→
Cardiotoxicity and neurobehavioral effects induced by acrylamide in Daphnia magna.	Eghan K et al.	—	2022	→
Cell-Type Specific Neuromodulation of Excitatory and Inhibitory Neurons <i>via</i> Muscarinic Acetylcholine Receptors in Layer 4 of Rat Barrel Cortex.	Qi G et al.	—	2022	→
Cell-type-specific synaptic modulation of mAChR on SST and PV interneurons.	Chen H et al.	—	2022	→
Cholinergic Modulation of Dendritic Signaling in Hippocampal GABAergic Inhibitory Interneurons.	Pancotti L et al.	—	2022	→
Combined Exposure to Chronic Sleep Deprivation and Caffeine Potentiates Behavioural Deficits by Altering Neurochemical Profile and Synaptophysin Expression in Long-Evans Rats.	Edem EE et al.	—	2022	→
Common Neuroanatomical Substrate of Cholinergic Pathways and Language-Related Brain Regions as an Explanatory Framework for Evaluating the Efficacy of Cholinergic Pharmacotherapy in Post-Stroke Aphasia: A Review.	Katsari M et al.	—	2022	→
Complementary roles of serotonergic and cholinergic systems in decisions about when to act.	Khalighinejad N et al.	—	2022	→
Corticofugal and Brainstem Functions Associated With Medial Olivocochlear Cholinergic Transmission.	Munoz F et al.	—	2022	→
Co-Treatment with the Herbal Medicine SIP3 and Donepezil Improves Memory and Depression in the Mouse Model of Alzheimer's Disease.	Liu QF et al.	—	2022	→
DE-71 affected the cholinergic system and locomotor activity via disrupting calcium homeostasis in zebrafish larvae.	Wang X et al.	—	2022	→
Deficient neurotransmitter systems and synaptic function in frontotemporal lobar degeneration-Insights into disease mechanisms and current therapeutic approaches.	Huber N et al.	—	2022	→
Design, synthesis and biological evaluation of light-driven on-off multitarget AChE and MAO-B inhibitors.	Paolino M et al.	—	2022	→
Diterpene Sonderianin isolated from <i>Croton blanchetianus</i> exhibits acetylcholinesterase inhibitory action and anxiolytic effect in adult zebrafish (<i>Danio rerio</i>) by 5-HT system.	Lima JDR et al.	—	2022	→
Dopamine plays a critical role in the olfactory adaptive learning pathway in Caenorhabditis elegans.	Raj V et al.	—	2022	→
Dorsal hippocampal muscarinic cholinergic receptors orchestrate behavioral and autonomic changes induced by contextual fear retrieval.	Diniz CRAF et al.	—	2022	→
Editorial: Neuromodulatory Function in Auditory Processing.	Burger RM et al.	—	2022	→
Effect of methylmercury on fetal neurobehavioral development: an overview of the possible mechanisms of toxicity and the neuroprotective effect of phytochemicals.	Bjørklund G et al.	—	2022	→
Effects of low dose ionizing radiation on the brain- a functional, cellular, and molecular perspective.	Narasimhamurthy RK et al.	—	2022	→
Effects of thymoquinone on scopolamine-induced spatial and echoic memory changes through regulation of lipid peroxidation and cholinergic impairment.	Kantar D et al.	—	2022	→
Efficacy of a vegetal mixture composed of <i>Zingiber officinale</i>, <i>Echinacea purpurea</i>, and <i>Centella asiatica</i> in a mouse model of neuroinflammation: <i>In vivo</i> and <i>ex vivo</i> analysis.	Micheli L et al.	—	2022	→
Electroacupuncture stimulation of HT7 alleviates sleep disruption following acute caffeine exposure by regulating BDNF-mediated endoplasmic reticulum stress in the rat medial septum.	Seo SY et al.	—	2022	→
Emerging Role of Neuron-Glia in Neurological Disorders: At a Glance.	Rahman MM et al.	—	2022	→
Enzymeless copper microspheres@carbon sensor design for sensitive and selective acetylcholine screening in human serum.	Emran MY et al.	—	2022	→
Estradiol treatment in young postmenopausal women with self-reported cognitive complaints: Effects on cholinergic-mediated cognitive performance.	Conley AC et al.	—	2022	→
Heat stress and evisceration caused lipid metabolism and neural transduction changes in sea cucumber: Evidence from metabolomics.	Huo D et al.	—	2022	→
Hippocampal acetylcholine modulates stress-related behaviors independent of specific cholinergic inputs.	Mineur YS et al.	—	2022	→
Impact of chronic sub-lethal methylparaben exposure on cardiac hypoxia and alterations in neuroendocrine factors in zebrafish model.	Thakkar S et al.	—	2022	→
Impacts of cetylpyridinium chloride on the behavior and brain neurotransmitter levels of juvenile and adult zebrafish (Danio rerio).	Dong K et al.	—	2022	→
Inconsistencies in atlas-based volumetric measures of the human nucleus basalis of Meynert: A need for high-resolution alternatives.	Wang Y et al.	—	2022	→
Increase in serum choline levels predicts for improved progression-free survival (PFS) in patients with advanced cancers receiving pembrolizumab.	Watson GA et al.	—	2022	→
Induction of distinct neuroinflammatory markers and gut dysbiosis by differential pyridostigmine bromide dosing in a chronic mouse model of GWI showing persistent exercise fatigue and cognitive impairment.	Kozlova EV et al.	—	2022	→
Influence of a Polyherbal Choline Source in Dogs: Body Weight Changes, Blood Metabolites, and Gene Expression.	Mendoza-Martínez GD et al.	—	2022	→
Into the Tissues: Extracellular Matrix and Its Artificial Substitutes: Cell Signalling Mechanisms.	Bandzerewicz A et al.	—	2022	→
Learning and memory impairment induced by 1,4-butanediol is regulated by ERK1/2-CREB-BDNF signaling pathways in PC12 cells.	Chen C et al.	—	2022	→
Long lasting effect of acute restraint stress on behavior and brain anti-oxidative status.	Chaoui N et al.	—	2022	→
Long-term exposure of the Mediterranean mussels, Mytilus galloprovincialis to polyethylene terephthalate microfibers: Implication for reproductive and neurotoxic effects.	Choi JS et al.	—	2022	→
Loss of GABA co-transmission from cholinergic neurons impairs behaviors related to hippocampal, striatal, and medial prefrontal cortex functions.	Goral RO et al.	—	2022	→
Malfunction of astrocyte and cholinergic input is involved in postoperative impairment of hippocampal synaptic plasticity and cognitive function.	Wang T et al.	—	2022	→
Metabolomics Analysis of the Prefrontal Cortex in a Rat Chronic Unpredictable Mild Stress Model of Depression.	Duan L et al.	—	2022	→
Mitochondria-Related Apoptosis Regulation by Minocycline: A Study on a Transgenic <i>Drosophila</i> Model of Alzheimer's Disease.	Khatoon R et al.	—	2022	→
Modulation of hippocampal plasticity in learning and memory.	Fuchsberger T et al.	—	2022	→
Molecularly defined and functionally distinct cholinergic subnetworks.	Li X et al.	—	2022	→
Muscarinic Acetylcholine Receptor Agonists as Novel Treatments for Schizophrenia.	Paul SM et al.	—	2022	→
Muscarinic acetylcholine receptors regulate inflammatory responses through arginases 1/2 in zebrafish.	Chen AQ et al.	—	2022	→
New Understanding on the Pathophysiology and Treatment of Constipation in Parkinson's Disease.	Xu J et al.	—	2022	→
Nicotinic receptors as SARS-CoV-2 spike co-receptors?	Dormoy V et al.	—	2022	→
Nicotinic receptors promote susceptibility to social stress in female mice linked with neuroadaptations within VTA dopamine neurons.	Ortiz V et al.	—	2022	→
Occupational risk assessment of organophosphates with an emphasis on psychological and oxidative stress factors.	Fghihi-Zarandi A et al.	—	2022	→
Outcome-Locked Cholinergic Signaling Suppresses Prefrontal Encoding of Stimulus Associations.	Tu G et al.	—	2022	→
Phenotypic Displays of Cholinergic Enzymes Associate With Markers of Inflammation, Neurofibrillary Tangles, and Neurodegeneration in Pre- and Early Symptomatic Dementia Subjects.	Teitsdottir UD et al.	—	2022	→
Potential of Heterogeneous Compounds as Antidepressants: A Narrative Review.	Hu G et al.	—	2022	→
Rat developmental fluoride exposure affects retention memory, leads to a depressive-like behavior, and induces biochemical changes in offspring rat brains.	Bartos M et al.	—	2022	→
Recent developments in the design and synthesis of benzylpyridinium salts: Mimicking donepezil hydrochloride in the treatment of Alzheimer's disease.	Sepehri S et al.	—	2022	→
Reduced <i>LYNX1</i> expression in transcriptome of human iPSC-derived neural progenitors modeling fragile X syndrome.	Talvio K et al.	—	2022	→
Region-Specific and Age-Dependent Multitarget Effects of Acetylcholinesterase Inhibitor Tacrine on Comprehensive Neurotransmitter Systems.	Fridjonsdottir E et al.	—	2022	→
Regulation of excitation-contraction coupling at the Drosophila neuromuscular junction.	Ormerod KG et al.	—	2022	→
Relaxation Effects of Essential Oils Are Explained by Their Interactions with Human Brain Neurotransmitter Receptors and Electroencephalography Rhythms.	Aponso M et al.	—	2022	→
Scalable Functionalization of Polyaniline-Grafted rGO Field-Effect Transistors for a Highly Sensitive Enzymatic Acetylcholine Biosensor.	Park D et al.	—	2022	→
Selective impairment of circuits between prefrontal cortex glutamatergic neurons and basal forebrain cholinergic neurons in a tauopathy mouse model.	Zhong P et al.	—	2022	→
Selenium nanoparticles impart robust neuroprotection against deltamethrin-induced neurotoxicity in male rats by reversing behavioral alterations, oxidative damage, apoptosis, and neuronal loss.	Khalil HMA et al.	—	2022	→
Single injection of very mild dose botulinum toxin in the vastus lateralis improves testicular spermatogenesis and sperm motility in ageing experimental mice.	Radhakrishnan RK et al.	—	2022	→
Spatiotemporally heterogeneous coordination of cholinergic and neocortical activity.	Lohani S et al.	—	2022	→
Synthesis, Biological Evaluation and Docking Study of Mono- and Di-Sulfonamide Derivatives as Antioxidant Agents and Acetylcholinesterase Inhibitors.	Güngör SA et al.	—	2022	→
Targeting the M1 muscarinic acetylcholine receptor in Alzheimer's disease.	Dwomoh L et al.	—	2022	→
Target-specific control of olfactory bulb periglomerular cells by GABAergic and cholinergic basal forebrain inputs.	De Saint Jan D	—	2022	→
Temporal dynamics of affect in the brain: Evidence from human imaging and animal models.	Puccetti NA et al.	—	2022	→
Temporal dynamics of cholinergic activity in the septo-hippocampal system.	Kopsick JD et al.	—	2022	→
The Aqueous Extract of <i>Humulus japonicus</i> Ameliorates Cognitive Dysfunction in Alzheimer's Disease Models via Modulating the Cholinergic System.	Kang CM et al.	—	2022	→
The Basal Forebrain Cholinergic Nuclei and Their Relevance to Schizophrenia and Other Psychotic Disorders.	Eickhoff S et al.	—	2022	→
The cholinergic system modulates negative BOLD responses in the prefrontal cortex once electrical perforant pathway stimulation triggers neuronal afterdischarges in the hippocampus.	Arboit A et al.	—	2022	→
The interaction between hippocampal cholinergic and nitrergic neurotransmission coordinates NMDA-dependent behavior and autonomic changes induced by contextual fear retrieval.	da Silva LA et al.	—	2022	→
The β2<sup>V287L</sup> nicotinic subunit linked to sleep-related epilepsy differently affects fast-spiking and regular spiking somatostatin-expressing neurons in murine prefrontal cortex.	Meneghini S et al.	—	2022	→
Tobacco and nicotine use.	Le Foll B et al.	—	2022	→
TOBACCO USE DISORDER AND DUAL DISORDERS Joint statement by the Spanish Psychiatry Society and the Spanish Dual Disorders Society.	Néstor S et al.	—	2022	→
Toxic Effects of Glyphosate on the Nervous System: A Systematic Review.	Costas-Ferreira C et al.	—	2022	→
TrkA-cholinergic signaling modulates fear encoding and extinction learning in PTSD-like behavior.	Yanpallewar S et al.	—	2022	→
Using Personality and Temperament to Predict Exercise Behavior: A Pilot Study of the Braverman Nature Assessment.	Rosicky BM et al.	—	2022	→
Xenobiotics Delivered by Electronic Nicotine Delivery Systems: Potential Cellular and Molecular Mechanisms on the Pathogenesis of Chronic Kidney Disease.	Scharf P et al.	—	2022	→
Acetylcholine and Royal Jelly Fatty Acid Combinations as Potential Dry Eye Treatment Components in Mice.	Yamaga M et al.	—	2021	→
Acetylcholine and spinal locomotor networks: The insider.	Mille T et al.	—	2021	→
Acetylcholine from the nucleus basalis magnocellularis facilitates the retrieval of well-established memory.	Soma S et al.	—	2021	→
Acetylcholinesterase and human cancers.	Richbart SD et al.	—	2021	→
Activation of 5-HT 1b/d receptor restores the cognitive function by reducing glutamate release, deposition of β-amyloid and TLR-4 pathway in the brain of scopolamine-induced dementia in rat.	Tripathi AS et al.	—	2021	→
Activity and Function of the PRMT8 Protein Arginine Methyltransferase in Neurons.	Dong R et al.	—	2021	→
Activity of Selected Group of Monoterpenes in Alzheimer's Disease Symptoms in Experimental Model Studies-A Non-Systematic Review.	Wojtunik-Kulesza K et al.	—	2021	→
Adolescent Ethanol Exposure Alters Cholinergic Function and Apical Dendritic Branching Within the Orbital Frontal Cortex.	Kipp BT et al.	—	2021	→
Altered Cortico-Subcortical Network After Adolescent Alcohol Exposure Mediates Behavioral Deficits in Flexible Decision-Making.	Gómez-A A et al.	—	2021	→
Analysing <i>Curcuma caesia</i> fractions and essential oil for neuroprotective potential against anxiety, depression, and amnesia.	Borah S et al.	—	2021	→
Anhedonia as a central factor in depression: Neural mechanisms revealed from preclinical to clinical evidence.	Wang S et al.	—	2021	→
Anticonvulsant and neuroprotective effects of carbamazepine-levetiracetam adjunctive treatment in convulsive status epilepticus rat model: Inhibition of cholinergic transmission.	Osuntokun OS et al.	—	2021	→
Anti-inflammatory Therapy by Cholinergic and Purinergic Modulation in Multiple Sclerosis Associated with SARS-CoV-2 Infection.	Simões JLB et al.	—	2021	→
BOTOX® counteracts the innate anxiety-related behaviours in correlation with increased activities of key antioxidant enzymes in the hippocampus of ageing experimental mice.	Yesudhas A et al.	—	2021	→
Changing the Cortical Conductor's Tempo: Neuromodulation of the Claustrum.	Wong KLL et al.	—	2021	→
Cholinergic neuromodulation of inhibitory interneurons facilitates functional integration in whole-brain models.	Coronel-Oliveros C et al.	—	2021	→
Cholinergic neurons constitutively engage the ISR for dopamine modulation and skill learning in mice.	Helseth AR et al.	—	2021	→
Cholinergic Receptor Modulation as a Target for Preventing Dementia in Parkinson's Disease.	Iarkov A et al.	—	2021	→
Cholinergic Signaling, Neural Excitability, and Epilepsy.	Wang Y et al.	—	2021	→
Cholinergic upregulation by optogenetic stimulation of nucleus basalis after photothrombotic stroke in forelimb somatosensory cortex improves endpoint and motor but not sensory control of skilled reaching in mice.	Mirza Agha B et al.	—	2021	→
Circuits for State-Dependent Modulation of Locomotion.	Pernía-Andrade AJ et al.	—	2021	→
Control of Brain State Transitions with a Photoswitchable Muscarinic Agonist.	Barbero-Castillo A et al.	—	2021	→
Cortical Responses to Vagus Nerve Stimulation Are Modulated by Brain State in Nonhuman Primates.	Rembado I et al.	—	2021	→
Cortical VIP<sup>+</sup> /ChAT<sup>+</sup> interneurons: From genetics to function.	Dudai A et al.	—	2021	→
Co-Treatment of Copper Oxide Nanoparticle and Carbofuran Enhances Cardiotoxicity in Zebrafish Embryos.	Saputra F et al.	—	2021	→
Cytisine Exerts an Anti-Epileptic Effect via α7nAChRs in a Rat Model of Temporal Lobe Epilepsy.	Zheng JJ et al.	—	2021	→
Dementia model mice exhibited improvements of neuropsychiatric symptoms as well as cognitive dysfunction with neural cell transplantation.	Murayama MA et al.	—	2021	→
Dietary Seleno-l-Methionine Causes Alterations in Neurotransmitters, Ultrastructure of the Brain, and Behaviors in Zebrafish (<i>Danio rerio</i>).	Li X et al.	—	2021	→
Distribution of the cholinergic nuclei in the brain of the weakly electric fish, Apteronotus leptorhynchus: Implications for sensory processing.	Toscano-Márquez B et al.	—	2021	→
Donepezil Ameliorates Pulmonary Arterial Hypertension by Inhibiting M2-Macrophage Activation.	Qiu H et al.	—	2021	→
Dynamic interplay of frontoparietal cholinergic innervation and cortical reorganization in the regulation of attentional capacities in aging.	Yegla B et al.	—	2021	→
Editorial: Animal Models of Stress - Current Knowledge and Potential Directions.	Pesarico AP et al.	—	2021	→
Effects of acetylcholine on hypoglossal and C4 nerve activity in brainstem-spinal cord preparations from newborn rat.	Katsuki S et al.	—	2021	→
Effects of nicotinic antagonists on working memory performance in young rhesus monkeys.	Upright NA et al.	—	2021	→
Effects of prenatal ethanol exposure on choline-induced long-term depression in the hippocampus.	Grafe EL et al.	—	2021	→
Electroacupuncture Ameliorates Depressive-Like State and Synaptic Deficits Induced by Hyper-Cholinergic Tone During Chronic Stress in Rats.	Gao J et al.	—	2021	→
Electrophysiological correlates of visual backward masking in patients with bipolar disorder.	Garobbio S et al.	—	2021	→
Examination of cortically projecting cholinergic neurons following exercise and environmental intervention in a rodent model of fetal alcohol spectrum disorders.	Milbocker KA et al.	—	2021	→
Excitatory-inhibitory tone shapes decision strategies in a hierarchical neural network model of multi-attribute choice.	Pettine WW et al.	—	2021	→
Experimental competition induces immediate and lasting effects on the neurogenome in free-living female birds.	Bentz AB et al.	—	2021	→
Extracellular Release of ILEI/FAM3C and Amyloid-β Is Associated with the Activation of Distinct Synapse Subpopulations.	Nakano M et al.	—	2021	→
Extrinsic neuromodulation in the rodent olfactory bulb.	Brunert D et al.	—	2021	→
From Research to Practice: Toward the Examination of Combined Interventions for Autism Spectrum Disorders.	London EB et al.	—	2021	→
Genetically encoded sensors enable micro- and nano-scopic decoding of transmission in healthy and diseased brains.	Lin L et al.	—	2021	→
G-Protein-Coupled Receptors in Astrocyte-Neuron Communication.	Kofuji P et al.	—	2021	→
Histamine H<sub>1</sub> receptor deletion in cholinergic neurons induces sensorimotor gating ability deficit and social impairments in mice.	Cheng L et al.	—	2021	→
Homomeric and Heteromeric α7 Nicotinic Acetylcholine Receptors in Health and Some Central Nervous System Diseases.	Borroni V et al.	—	2021	→
How Psychoactive Drugs and the Circadian Clock Are Enlightening One Another.	Engmann O	—	2021	→
Implications of Oligomeric Amyloid-Beta (oAβ<sub>42</sub>) Signaling through α7β2-Nicotinic Acetylcholine Receptors (nAChRs) on Basal Forebrain Cholinergic Neuronal Intrinsic Excitability and Cognitive Decline.	George AA et al.	—	2021	→
Inhibition of Matrix Metalloproteinase 9 Activity Promotes Synaptogenesis in the Hippocampus.	Salamian A et al.	—	2021	→
In Vitro and In Silico Kinetic Studies of Patented 1,7-diEthyl and 1,7-diMethyl Aminoalkanol Derivatives as New Inhibitors of Acetylcholinesterase.	Grodner B et al.	—	2021	→
Journey on Naphthoquinone and Anthraquinone Derivatives: New Insights in Alzheimer's Disease.	Campora M et al.	—	2021	→
Lower cholinergic basal forebrain volumes link with cognitive difficulties in schizophrenia.	Avram M et al.	—	2021	→
Make a Left Turn: Cortico-Striatal Circuitry Mediating the Attentional Control of Complex Movements.	Sarter M et al.	—	2021	→
Mapping Metabolic Networks in the Brain by Ambient Mass Spectrometry Imaging and Metabolomics.	Pang X et al.	—	2021	→
Mecamylamine inhibits seizure-like activity in CA1-CA3 hippocampus through antagonism to nicotinic receptors.	Zapukhliak O et al.	—	2021	→
Mechanisms of GABAergic and cholinergic neurotransmission in auditory thalamus: Impact of aging.	Richardson BD et al.	—	2021	→
Medial prefrontal cortical control of reward- and aversion-based behavioral output: Bottom-up modulation.	Pastor V et al.	—	2021	→
Melamine Disrupts Acetylcholine-Mediated Neural Information Flow in the Hippocampal CA3-CA1 Pathway.	Sun W et al.	—	2021	→
Modulation of Predator Cue-Evoked Tonic Immobility by Acetylcholine Released in the Basolateral Complex of the Amygdala.	Liu N et al.	—	2021	→
Molecular characterization of the stress network in individuals at risk for schizophrenia.	Meijer M et al.	—	2021	→
Molecular fMRI of neurochemical signaling.	Wei H et al.	—	2021	→
Molecular photoswitches in aqueous environments.	Volarić J et al.	—	2021	→
Muscarinic Acetylcholine Receptor Localization on Distinct Excitatory and Inhibitory Neurons Within the ACC and LPFC of the Rhesus Monkey.	Tsolias A et al.	—	2021	→
Neurochemical and Behavioral Effects of a New Hallucinogenic Compound 25B-NBOMe in Rats.	Wojtas A et al.	—	2021	→
Neurochemistry of Visual Attention.	Lockhofen DEL et al.	—	2021	→
Neuromodulation of Persistent Activity and Working Memory Circuitry in Primate Prefrontal Cortex by Muscarinic Receptors.	Vijayraghavan S et al.	—	2021	→
Neuromodulatory Control of Early Visual Processing in Macaque.	Disney AA	—	2021	→
Neuromodulatory potential of Asparagus racemosus and its bioactive molecule Shatavarin IV by enhancing synaptic acetylcholine level and nAChR activity.	Shuchi Smita S et al.	—	2021	→
Neuron-specific responses to acetylcholine within the spinal dorsal horn circuits of rodent and primate.	Sykes MJ et al.	—	2021	→
Neuroprotection elicited by resveratrol in a rat model of hypothyroidism: Possible involvement of cholinergic signaling and redox status.	de Souza Cardoso J et al.	—	2021	→
Neurotransmitter Dysfunction in Irritable Bowel Syndrome: Emerging Approaches for Management.	Gros M et al.	—	2021	→
New Approaches to Profile the Microbiome for Treatment of Neurodegenerative Disease.	Elmaleh DR et al.	—	2021	→
Newly-Discovered Neural Features Expand the Pathobiological Knowledge of Blastic Plasmacytoid Dendritic Cell Neoplasm.	Sapienza MR et al.	—	2021	→
Nicotinic Acetylcholine Receptor α7 Subunit Is an Essential Regulator of Seizure Susceptibility.	Sun P et al.	—	2021	→
Noninvasive vagus nerve stimulation in Parkinson's disease: current status and future prospects.	Sigurdsson HP et al.	—	2021	→
Novel test strategies for in vitro seizure liability assessment.	Tukker AM et al.	—	2021	→
Pharmacological reversal of synaptic and network pathology in human MECP2-KO neurons and cortical organoids.	Trujillo CA et al.	—	2021	→
Pharmacotherapy of substance use disorders in the neuroscience-based nomenclature (NbN).	Carton L et al.	—	2021	→
Predicting the relationships between gut microbiota and mental disorders with knowledge graphs.	Liu T et al.	—	2021	→
Prefrontal-Hippocampal Pathways Through the Nucleus Reuniens Are Functionally Biased by Brain State.	Hauer BE et al.	—	2021	→
Preoperative Comparison of Three Anticholinergic Drug Scales in Older Adult Patients and Development of Postoperative Delirium: A Prospective Observational Study.	Heinrich M et al.	—	2021	→
Rapid multi-directed cholinergic transmission in the central nervous system.	Sethuramanujam S et al.	—	2021	→
Reduction of falls in a rat model of PD falls by the M1 PAM TAK-071.	Kucinski A et al.	—	2021	→
Regulation of Neurotransmitters by the Gut Microbiota and Effects on Cognition in Neurological Disorders.	Chen Y et al.	—	2021	→
Role of the Nucleus Basalis as a Key Network Node in Temporal Lobe Epilepsy.	González HFJ et al.	—	2021	→
Serum choline in extremely preterm infants declines with increasing parenteral nutrition.	Nilsson AK et al.	—	2021	→
Severity of Lesions Involving the Cortical Cholinergic Pathways May Be Associated With Cognitive Impairment in Subacute Ischemic Stroke.	Zhong HH et al.	—	2021	→
Spatial topography of the basal forebrain cholinergic projections: Organization and vulnerability to degeneration.	Schmitz TW et al.	—	2021	→
Stimulants cocktail: Methylphenidate plus caffeine impairs memory and cognition and alters mitochondrial and oxidative status.	Freddo N et al.	—	2021	→
Subacute and chronic neuropsychological sequalae of acute organophosphate pesticide self-poisoning: a prospective cohort study from Sri Lanka.	Dassanayake TL et al.	—	2021	→
Systematic Review of Calcium Channels and Intracellular Calcium Signaling: Relevance to Pesticide Neurotoxicity.	Costas-Ferreira C et al.	—	2021	→
Temporal regulation of nicotinic acetylcholine receptor subunits supports central cholinergic synapse development in <i>Drosophila</i>.	Rosenthal JS et al.	—	2021	→
The Biology and Pathobiology of Glutamatergic, Cholinergic, and Dopaminergic Signaling in the Aging Brain.	Gasiorowska A et al.	—	2021	→
The Cholinergic Brain in Parkinson's Disease.	Pasquini J et al.	—	2021	→
The Cholinergic System, the Adrenergic System and the Neuropathology of Alzheimer's Disease.	Bekdash RA	—	2021	→
The Effects of Statins on Neurotransmission and Their Neuroprotective Role in Neurological and Psychiatric Disorders.	Kosowski M et al.	—	2021	→
The Impact of Anticholinergic Burden on Functional Capacity in Persons With Schizophrenia Across the Adult Life Span.	Khan WU et al.	—	2021	→
The M1/M4 preferring muscarinic agonist xanomeline modulates functional connectivity and NMDAR antagonist-induced changes in the mouse brain.	Montani C et al.	—	2021	→
The Phenotypic Spectrum of 15q13.3 Region Duplications: Report of 5 Patients.	Budisteanu M et al.	—	2021	→
The potential involvement of cholinergic system in finasteride induced cognitive dysfunction.	Ahire A et al.	—	2021	→
The Property-Based Practical Applications and Solutions of Genetically Encoded Acetylcholine and Monoamine Sensors.	Chen J et al.	—	2021	→
The role of acetylcholine in negative encoding bias: Too much of a good thing?	Mineur YS et al.	—	2021	→
The Role of G Protein-Coupled Receptors (GPCRs) and Calcium Signaling in Schizophrenia. Focus on GPCRs Activated by Neurotransmitters and Chemokines.	Boczek T et al.	—	2021	→
The transcriptomic blueprint of molt in rooster using various tissues from Ginkkoridak (Korean long-tailed chicken).	Charton C et al.	—	2021	→
Tolerance to neurochemical and behavioral effects of the hallucinogen 25I-NBOMe.	Herian M et al.	—	2021	→
Transcriptomics and sequencing analysis of gene expression profiling for major depressive disorder.	Verma P et al.	—	2021	→
Trans-inhibition of axon terminals underlies competition in the habenulo-interpeduncular pathway.	Zaupa M et al.	—	2021	→
Unveiling the pathogenesis of perineural invasion from the perspective of neuroactive molecules.	Melgarejo da Rosa M et al.	—	2021	→
Ventral tegmental area GABAergic inhibition of cholinergic interneurons in the ventral nucleus accumbens shell promotes reward reinforcement.	Al-Hasani R et al.	—	2021	→
Acetylcholine in action.	Wall EM et al.	—	2020	→
Acetylcholine is released in the basolateral amygdala in response to predictors of reward and enhances the learning of cue-reward contingency.	Crouse RB et al.	—	2020	→
Acetylcholine Muscarinic Receptors in Ventral Hippocampus Modulate Stress-Induced Anxiety-Like Behaviors in Mice.	Mei L et al.	—	2020	→
An optimized acetylcholine sensor for monitoring in vivo cholinergic activity.	Jing M et al.	—	2020	→
Approaches to Monitor Circuit Disruption after Traumatic Brain Injury: Frontiers in Preclinical Research.	Krishna G et al.	—	2020	→
Assessment of Ketamine and Its Enantiomers in an Organophosphate-Based Rat Model for Features of Gulf War Illness.	Zhu J et al.	—	2020	→
Astrocytes-The Ultimate Effectors of Long-Range Neuromodulatory Networks?	Pacholko AG et al.	—	2020	→
Beyond neurotransmission: acetylcholine in immunity and inflammation.	Cox MA et al.	—	2020	→
Biosensing based on field-effect transistors (FET): Recent progress and challenges.	Sadighbayan D et al.	—	2020	→
Cellular birthdate predicts laminar and regional cholinergic projection topography in the forebrain.	Allaway KC et al.	—	2020	→
Changes in gray matter volume and functional connectivity in dementia with Lewy bodies compared to Alzheimer's disease and normal aging: implications for fluctuations.	Chabran E et al.	—	2020	→
Cholinergic Markers and Cytokines in OSA Patients.	Reale M et al.	—	2020	→
Cholinergic System and NGF Receptors: Insights from the Brain of the Short-Lived Fish <i>Nothobranchius furzeri</i>.	de Girolamo P et al.	—	2020	→
Common neurodegenerative disorders in the perioperative setting: Recommendations for screening from the Society for Perioperative Assessment and Quality Improvement (SPAQI).	Wiggins M et al.	—	2020	→
Cortical ChAT<sup>+</sup> neurons co-transmit acetylcholine and GABA in a target- and brain-region-specific manner.	Granger AJ et al.	—	2020	→
Crystal structure of 4-methyl-<i>N</i>-propyl-benzene-sulfonamide.	Stenfors BA et al.	—	2020	→
Detrimental association between quadriceps strength and exposure to polycyclic aromatic hydrocarbons in elderly adults.	Chen YY et al.	—	2020	→
Dietary phospholipids: Role in cognitive processes across the lifespan.	Schverer M et al.	—	2020	→
Diverse Spatiotemporal Scales of Cholinergic Signaling in the Neocortex.	Disney AA et al.	—	2020	→
Do Nicotinic Receptors Modulate High-Order Cognitive Processing?	Koukouli F et al.	—	2020	→
Dual-Ionomer-Based Device: Acetylcholine Transport and Nonenzymatic Sensing.	Abdullayeva N et al.	—	2020	→
Dual recombinase fate mapping reveals a transient cholinergic phenotype in multiple populations of developing glutamatergic neurons.	Nasirova N et al.	—	2020	→
Duplicated <i>dnmt3aa</i> and <i>dnmt3ab</i> DNA Methyltransferase Genes Play Essential and Non-Overlapped Functions on Modulating Behavioral Control in Zebrafish.	Lai YH et al.	—	2020	→
Dynamic regulation of the cholinergic system in the spinal central nervous system.	Rima M et al.	—	2020	→
Effects of Prolonged Seizures on Basal Forebrain Cholinergic Neurons: Evidence and Potential Clinical Relevance.	Giorgi FS et al.	—	2020	→
Environmental Enrichment as a Strategy to Confront Social Isolation Under the COVID-19 Pandemic.	Davim A et al.	—	2020	→
Epigenomically Bistable Regions across Neuron-Specific Genes Govern Neuron Eligibility to a Coding Ensemble in the Hippocampus.	Odell SC et al.	—	2020	→
Evaluation of the pre-treatment effect of Centella asiatica medicinal plants on long-term potentiation (LTP) in rat model of Alzheimer's disease.	Doulah A et al.	—	2020	→
Fine Tuning Muscarinic Acetylcholine Receptor Signaling Through Allostery and Bias.	van der Westhuizen ET et al.	—	2020	→
Forebrain Cholinergic Signaling: Wired and Phasic, Not Tonic, and Causing Behavior.	Sarter M et al.	—	2020	→
Galantamine improves enhanced impulsivity, impairments of attention and long-term potentiation induced by prenatal nicotine exposure to mice.	Mamiya T et al.	—	2020	→
GPCR-Based Dopamine Sensors-A Detailed Guide to Inform Sensor Choice for In vivo Imaging.	Labouesse MA et al.	—	2020	→
Human Dermal Fibroblast: A Promising Cellular Model to Study Biological Mechanisms of Major Depression and Antidepressant Drug Response.	Mesdom P et al.	—	2020	→
Hyper-Activation of mPFC Underlies Specific Traumatic Stress-Induced Sleep-Wake EEG Disturbances.	Lou T et al.	—	2020	→
Identification of substances which regulate activity of corticotropin-releasing factor-producing neurons in the paraventricular nucleus of the hypothalamus.	Mukai Y et al.	—	2020	→
<i>In Vivo</i> Attenuation of M-Current Suppression Impairs Consolidation of Object Recognition Memory.	Kosenko A et al.	—	2020	→
Impaired context-sensitive adjustment of behaviour in Parkinson's disease patients tested on and off medication: An fMRI study.	Trempler I et al.	—	2020	→
Inhibitory neurotransmission drives endocannabinoid degradation to promote memory consolidation.	Dubois CJ et al.	—	2020	→
Input dependent modulation of olfactory bulb activity by HDB GABAergic projections.	Böhm E et al.	—	2020	→
Layer-specific serotonergic induction of long-term depression in the prefrontal cortex of rats.	Shin D et al.	—	2020	→
Machine Learning Neuroprotective Strategy Reveals a Unique Set of Parkinson Therapeutic Nicotine Analogs.	Rojas-Rodríguez F et al.	—	2020	→
MeCP2 in cholinergic interneurons of nucleus accumbens regulates fear learning.	Zhang Y et al.	—	2020	→
Metabolite Profile Changes in Different Regions of Rat Brain Affected by <i>Ephedra sinica</i>.	Liao Z et al.	—	2020	→
MicroRNA-Based Multitarget Approach for Alzheimer's Disease: Discovery of the First-In-Class Dual Inhibitor of Acetylcholinesterase and MicroRNA-15b Biogenesis.	Gabr MT et al.	—	2020	→
Modulation of cholinergic activity through lynx prototoxins: Implications for cognition and anxiety regulation.	Anderson KR et al.	—	2020	→
Molecular docking and in vitro evaluation of a new hybrid molecule (JM-20) on cholinesterase activity from different sources.	D'Avila da Silva F et al.	—	2020	→
Muscarinic receptors in energy homeostasis: Physiology and pharmacology.	Falk S et al.	—	2020	→
Neural Compensation Mechanisms of Siblings of Schizophrenia Patients as Revealed by High-Density EEG.	da Cruz JR et al.	—	2020	→
Neurochemical mechanisms for memory processing during sleep: basic findings in humans and neuropsychiatric implications.	Feld GB et al.	—	2020	→
Nicotine evoked efferent transmitter release onto immature cochlear inner hair cells.	Zhang Y et al.	—	2020	→
Nicotinic Receptors in Sleep-Related Hypermotor Epilepsy: Pathophysiology and Pharmacology.	Becchetti A et al.	—	2020	→
Noise and brain.	Arjunan A et al.	—	2020	→
Organophosphorus Nerve Agents: Types, Toxicity, and Treatments.	Mukherjee S et al.	—	2020	→
Possible Correlation between Cholinergic System Alterations and Neuro/Inflammation in Multiple Sclerosis.	Gatta V et al.	—	2020	→
Postoperative delirium: perioperative assessment, risk reduction, and management.	Jin Z et al.	—	2020	→
Potential frameworks to support evaluation of mechanistic data for developmental neurotoxicity outcomes: A symposium report.	Carlson LM et al.	—	2020	→
Progress in nicotinic receptor structural biology.	Gharpure A et al.	—	2020	→
Proton Magnetic Resonance Spectroscopy to Detect Correlations between Clinical Symptoms and Brain Metabolite Levels in Patients with Tension-type Headache.	M M et al.	—	2020	→
Psychobiotics: Mechanisms of Action, Evaluation Methods and Effectiveness in Applications with Food Products.	Del Toro-Barbosa M et al.	—	2020	→
Real-time <i>in vivo</i> detection techniques for neurotransmitters: a review.	Su Y et al.	—	2020	→
Recent developments of bioanalytical methods in determination of neurotransmitters in vivo.	Matys J et al.	—	2020	→
Role of the α7 Nicotinic Acetylcholine Receptor in the Pathophysiology of Atherosclerosis.	Vieira-Alves I et al.	—	2020	→
Solar light induces the release of acetylcholine from skin keratinocytes affecting melanogenesis.	Wu Q et al.	—	2020	→
Synthesis of Quercetin-Metal Complexes, In Vitro and In Silico Anticholinesterase and Antioxidant Evaluation, and In Vivo Toxicological and Anxiolitic Activities.	da Silva WMB et al.	—	2020	→
Taenia larvae possess distinct acetylcholinesterase profiles with implications for host cholinergic signalling.	de Lange A et al.	—	2020	→
The Basal Forebrain Modulates Neuronal Response in an Active Olfactory Discrimination Task.	Nunez-Parra A et al.	—	2020	→
Transcutaneous auricular vagus nerve stimulation enhances learning of novel letter-sound relationships in adults.	Thakkar VJ et al.	—	2020	→
Zika Virus Infection Results in Biochemical Changes Associated With RNA Editing, Inflammatory and Antiviral Responses in <i>Aedes albopictus</i>.	Onyango MG et al.	—	2020	→
Acetylcholine signaling system in progression of lung cancers.	Friedman JR et al.	—	2019	→
A cortical model with multi-layers to study visual attentional modulation of neurons at the synaptic level.	Zhang T et al.	—	2019	→
Alzheimer's Disease Pharmacotherapy in Relation to Cholinergic System Involvement.	Stanciu GD et al.	—	2019	→
Anti-Oxidant Activity of Gallotannin-Enriched Extract of Galla Rhois Can Associate with the Protection of the Cognitive Impairment through the Regulation of BDNF Signaling Pathway and Neuronal Cell Function in the Scopolamine-Treated ICR Mice.	Park JW et al.	—	2019	→
Artificial neural networks-based classification of emotions using wristband heart rate monitor data.	Chen YC et al.	—	2019	→
A whole-brain map of long-range inputs to GABAergic interneurons in the mouse medial prefrontal cortex.	Sun Q et al.	—	2019	→
Behavioral and Biochemical Implications of Dendrimeric Rivastigmine in Memory-Deficit and Alzheimer's Induced Rodents.	Gothwal A et al.	—	2019	→
Choline Is an Intracellular Messenger Linking Extracellular Stimuli to IP<sub>3</sub>-Evoked Ca<sup>2+</sup> Signals through Sigma-1 Receptors.	Brailoiu E et al.	—	2019	→
Cholinergic Control of Inflammation, Metabolic Dysfunction, and Cognitive Impairment in Obesity-Associated Disorders: Mechanisms and Novel Therapeutic Opportunities.	Chang EH et al.	—	2019	→
Cholinergic Modulation Promotes Attentional Modulation in Primary Visual Cortex- A Modeling Study.	Sajedin A et al.	—	2019	→
Cholinergic nervous system and glaucoma: From basic science to clinical applications.	Faiq MA et al.	—	2019	→
Cholinergic system and exploratory behavior are changed after weekly-binge ethanol exposure in zebrafish.	Bernardo HT et al.	—	2019	→
Cholinergic system in sleep regulation of emotion and motivation.	Mu P et al.	—	2019	→
Critical Period Regulation by Thyroid Hormones: Potential Mechanisms and Sex-Specific Aspects.	Batista G et al.	—	2019	→
Determination of sinapine in rapeseed pomace extract: Its antioxidant and acetylcholinesterase inhibition properties.	Yates K et al.	—	2019	→
Development and validation of a dynamic delirium prediction rule in patients admitted to the Intensive Care Units (DYNAMIC-ICU): A prospective cohort study.	Fan H et al.	—	2019	→
Dietary Supplementation with Fish Oil or Conjugated Linoleic Acid Relieves Depression Markers in Mice by Modulation of the Nrf2 Pathway.	Cigliano L et al.	—	2019	→
Effects of Cholinergic Neuromodulation on Thalamocortical Rhythms During NREM Sleep: A Model Study.	Li Q et al.	—	2019	→
Effects of Phytochemicals on Blood Pressure and Neuroprotection Mediated Via Brain Renin-Angiotensin System.	Kim HR et al.	—	2019	→
Embelin Protects Against Acute Pentylenetetrazole-Induced Seizures and Positively Modulates Cognitive Function in Adult Zebrafish.	Kundap UP et al.	—	2019	→
Enabling biodegradable functional biomaterials for the management of neurological disorders.	Shan D et al.	—	2019	→
Fatigue, Sleep, and Autoimmune and Related Disorders.	Zielinski MR et al.	—	2019	→
Fermented rice peptides attenuate scopolamine-induced memory impairment in mice by regulating neurotrophic signaling pathways in the hippocampus.	Corpuz HM et al.	—	2019	→
Fluorescent Biosensors for Neurotransmission and Neuromodulation: Engineering and Applications.	Leopold AV et al.	—	2019	→
Forebrain Cholinergic Signaling Regulates Innate Immune Responses and Inflammation.	Lehner KR et al.	—	2019	→
Fornix deep brain stimulation induces reduction of hippocampal synaptophysin levels.	Aldehri M et al.	—	2019	→
Frontal cortex and striatal cellular and molecular pathobiology in individuals with Down syndrome with and without dementia.	Perez SE et al.	—	2019	→
Frontiers in Electrochemical Sensors for Neurotransmitter Detection: Towards Measuring Neurotransmitters as Chemical Diagnostics for Brain Disorders.	Ou Y et al.	—	2019	→
Genome-wide discovery of the daily transcriptome, DNA regulatory elements and transcription factor occupancy in the monarch butterfly brain.	Lugena AB et al.	—	2019	→
Identification of neuron-type specific promoters in monkey genome and their functional validation in mice.	Nagai Y et al.	—	2019	→
Is there a role for antibodies targeting muscarinic acetylcholine receptors in the pathogenesis of schizophrenia?	Ryan AE et al.	—	2019	→
M1 muscarinic receptors facilitate hippocampus-dependent cognitive flexibility via modulating GluA2 subunit of AMPA receptors.	Xiong CH et al.	—	2019	→
Metabolic treatment of syndrome linked with Parkinson's disease and hypothalamus pituitary gonadal hormones by turmeric curcumin in Bisphenol-A induced neuro-testicular dysfunction of wistar rat.	Akintunde JK et al.	—	2019	→
Methionine-Choline Deprivation Impairs Adult Hippocampal Neurogenesis in C57BL/6 Mice.	Kim JW et al.	—	2019	→
Modulation of the extraneuronal cholinergic system on main innate response leukocytes.	Eduardo CC et al.	—	2019	→
Neural circuits for a top-down control of fear and extinction.	Marek R et al.	—	2019	→
Nicotine Acts on Cholinergic Signaling Mechanisms to Directly Modulate Choroid Plexus Function.	Lallai V et al.	—	2019	→
NMDA Receptor-Dependent Cholinergic Modulation of Mesolimbic Dopamine Cell Bodies: Neurochemical and Behavioral Studies.	Spanos M et al.	—	2019	→
Oligodendrocyte involvement in Gulf War Illness.	Belgrad J et al.	—	2019	→
Prefrontal circuit organization for executive control.	Kamigaki T	—	2019	→
Probing spatial inhomogeneity of cholinergic changes in cortical state in rat.	Nur T et al.	—	2019	→
Remembering to Forget: A Dual Role for Sleep Oscillations in Memory Consolidation and Forgetting.	Langille JJ	—	2019	→
Remodeling of cholinergic input to the hippocampus after noise exposure and tinnitus induction in Guinea pigs.	Zhang L et al.	—	2019	→
Roles of the M<sub>4</sub> acetylcholine receptor in the basal ganglia and the treatment of movement disorders.	Moehle MS et al.	—	2019	→
Selective attenuation of Ether-a-go-go related K<sup>+</sup> currents by endogenous acetylcholine reduces spike-frequency adaptation and network correlation.	Cui ED et al.	—	2019	→
Sensory perception drives food avoidance through excitatory basal forebrain circuits.	Patel JM et al.	—	2019	→
Stimulating muscarinic M<sub>1</sub> receptors in the anterior cingulate cortex reduces mechanical hypersensitivity via GABAergic transmission in nerve injury rats.	Koga K et al.	—	2019	→
Structural Insights Into the Dynamic Evolution of Neuronal Networks as Synaptic Density Decreases.	Yuan Y et al.	—	2019	→
Targeting Muscarinic Acetylcholine Receptors for the Treatment of Psychiatric and Neurological Disorders.	Moran SP et al.	—	2019	→
The cellular basis of fetal endoplasmic reticulum stress and oxidative stress in drug-induced neurodevelopmental deficits.	Tsai SA et al.	—	2019	→
The effect of psychotropic drugs on cortical excitability and plasticity measured with transcranial magnetic stimulation: Implications for psychiatric treatment.	Minzenberg MJ et al.	—	2019	→
The effects of crocin on spatial memory impairment induced by hyoscine: Role of NMDA, AMPA, ERK, and CaMKII proteins in rat hippocampus.	Adabizadeh M et al.	—	2019	→
The effects of zingerone against vancomycin-induced lung, liver, kidney and testis toxicity in rats: The behavior of some metabolic enzymes.	Çağlayan C et al.	—	2019	→
The Medial Septum Is Insulin Resistant in the AD Presymptomatic Phase: Rescue by Nerve Growth Factor-Driven IRS<sub>1</sub> Activation.	Sposato V et al.	—	2019	→
The molecular and cellular mechanisms of depression: a focus on reward circuitry.	Fox ME et al.	—	2019	→
Therapeutic Potential of Multifunctional Tacrine Analogues.	Przybyłowska M et al.	—	2019	→
Transcriptome Profile in Hippocampus During Acute Inflammatory Response to Surgery: Toward Early Stage of PND.	Xiang X et al.	—	2019	→
Whole-Brain Mapping of Monosynaptic Afferent Inputs to Cortical CRH Neurons.	Zhang S et al.	—	2019	→
α7 nicotinic ACh receptors are necessary for memory recovery and neuroprotection promoted by attention training in amyloid-β-infused mice.	Telles-Longui M et al.	—	2019	→
Ablation of the presynaptic organizer Bassoon in excitatory neurons retards dentate gyrus maturation and enhances learning performance.	Annamneedi A et al.	—	2018	→
Acetylcholine-modulated plasticity in reward-driven navigation: a computational study.	Zannone S et al.	—	2018	→
A genetically encoded fluorescent acetylcholine indicator for in vitro and in vivo studies.	Jing M et al.	—	2018	→
Anhydroecgonine Methyl Ester (AEME), a Product of Cocaine Pyrolysis, Impairs Spatial Working Memory and Induces Striatal Oxidative Stress in Rats.	Gomes EF et al.	—	2018	→
Cell Type- and Layer-Specific Muscarinic Potentiation of Excitatory Synaptic Drive onto Parvalbumin Neurons in Mouse Prefrontal Cortex.	Tikhonova TB et al.	—	2018	→
Changes in electrophysiological markers of cognitive control after administration of galantamine.	Gascoyne LE et al.	—	2018	→
Cholinergic and purinergic systems: A key to multiple sclerosis?	Polachini CRN et al.	—	2018	→
Cholinergic excitation complements glutamate in coding visual information in retinal ganglion cells.	Sethuramanujam S et al.	—	2018	→
Cognitive Control, the Anterior Cingulate, and Nicotinic Receptors: A Case of Heterozygote Advantage.	Smucny J	—	2018	→
Constraints of Metabolic Energy on the Number of Synaptic Connections of Neurons and the Density of Neuronal Networks.	Yuan Y et al.	—	2018	→
Control of synaptic plasticity in deep cortical networks.	Roelfsema PR et al.	—	2018	→
Co-transmission of acetylcholine and GABA regulates hippocampal states.	Takács VT et al.	—	2018	→
Data-Driven Modeling of Cholinergic Modulation of Neural Microcircuits: Bridging Neurons, Synapses and Network Activity.	Ramaswamy S et al.	—	2018	→
Energetic evolution of cellular Transportomes.	Darbani B et al.	—	2018	→
Exploring the potential of marine microbes in clinical management of Alzheimer's disease: A road map for bioprospecting and identifying promising isolates.	Muralidharan A et al.	—	2018	→
Genomic Understanding of an Infectious Brain Disease from the Desert.	Moreno LF et al.	—	2018	→
Hypoxia-Induced Neuroinflammation and Learning-Memory Impairments in Adult Zebrafish Are Suppressed by Glucosamine.	Lee Y et al.	—	2018	→
Identification of new risk factors for rolandic epilepsy: CNV at Xp22.31 and alterations at cholinergic synapses.	Addis L et al.	—	2018	→
Immunocytochemical Localization of Choline Acetyltransferase in the Microbat Visual Cortex.	Kim GH et al.	—	2018	→
Impaired object-location learning and recognition memory but enhanced sustained attention in M2 muscarinic receptor-deficient mice.	Romberg C et al.	—	2018	→
Inferring anatomical therapeutic chemical (ATC) class of drugs using shortest path and random walk with restart algorithms.	Chen L et al.	—	2018	→
Information processing across behavioral states: Modes of operation and population dynamics in rodent sensory cortex.	Sabri MM et al.	—	2018	→
Interaction between noradrenergic and cholinergic signaling in amygdala regulates anxiety- and depression-related behaviors in mice.	Mineur YS et al.	—	2018	→
Long-Lasting Electrophysiological After-Effects of High-Frequency Stimulation in the Globus Pallidus: Human and Rodent Slice Studies.	Luo F et al.	—	2018	→
M1 muscarinic receptor facilitates cognitive function by interplay with AMPA receptor GluA1 subunit.	Zhao LX et al.	—	2018	→
Manipulating midbrain dopamine neurons and reward-related behaviors with light-controllable nicotinic acetylcholine receptors.	Durand-de Cuttoli R et al.	—	2018	→
Mesopontine cholinergic inputs to midbrain dopamine neurons drive stress-induced depressive-like behaviors.	Fernandez SP et al.	—	2018	→
Minimal Circuit Model of Reward Prediction Error Computations and Effects of Nicotinic Modulations.	Deperrois N et al.	—	2018	→
Modulation of cortical circuits by top-down processing and arousal state in health and disease.	Batista-Brito R et al.	—	2018	→
Molecular, Cellular and Circuit Basis of Cholinergic Modulation of Pain.	Naser PV et al.	—	2018	→
Muscarinic M1 Receptor Overstimulation Disrupts Working Memory Activity for Rules in Primate Prefrontal Cortex.	Vijayraghavan S et al.	—	2018	→
Nerve Agents: What They Are, How They Work, How to Counter Them.	Costanzi S et al.	—	2018	→
Neurotransmitter deficits from frontotemporal lobar degeneration.	Murley AG et al.	—	2018	→
NOAEL-dose of a neonicotinoid pesticide, clothianidin, acutely induce anxiety-related behavior with human-audible vocalizations in male mice in a novel environment.	Hirano T et al.	—	2018	→
Nuclear organization and morphology of cholinergic neurons in the brain of the rock cavy (Kerodon rupestris) (Wied, 1820).	Resende NR et al.	—	2018	→
Ocular Nerve Growth Factor (NGF) and NGF Eye Drop Application as Paradigms to Investigate NGF Neuroprotective and Reparative Actions.	Tirassa P et al.	—	2018	→
Palmitoylation as a Functional Regulator of Neurotransmitter Receptors.	Naumenko VS et al.	—	2018	→
Pharmacological Modulation of Long-Term Potentiation-Like Activity in the Dorsolateral Prefrontal Cortex.	Salavati B et al.	—	2018	→
Physiological roles of CNS muscarinic receptors gained from knockout mice.	Thomsen M et al.	—	2018	→
Planarian cholinesterase: molecular and functional characterization of an evolutionarily ancient enzyme to study organophosphorus pesticide toxicity.	Hagstrom D et al.	—	2018	→
Positive allosteric modulation of M<sub>1</sub> and M<sub>4</sub> muscarinic receptors as potential therapeutic treatments for schizophrenia.	Yohn SE et al.	—	2018	→
Potential of Low Dose Leuco-Methylthioninium Bis(Hydromethanesulphonate) (LMTM) Monotherapy for Treatment of Mild Alzheimer's Disease: Cohort Analysis as Modified Primary Outcome in a Phase III Clinical Trial.	Wilcock GK et al.	—	2018	→
Precisely Timed Nicotinic Activation Drives SST Inhibition in Neocortical Circuits.	Urban-Ciecko J et al.	—	2018	→
Real-Time Monitoring of Chemical Changes in Three Kinds of Fermented Milk Products during Fermentation Using Quantitative Difference Nuclear Magnetic Resonance Spectroscopy.	Lu Y et al.	—	2018	→
Reduction of the Anticholinergic Burden Makes It Possible to Decrease Behavioral and Psychological Symptoms of Dementia.	Jaïdi Y et al.	—	2018	→
Scaling Our World View: How Monoamines Can Put Context Into Brain Circuitry.	Stratmann P et al.	—	2018	→
Segregation of the human basal forebrain using resting state functional MRI.	Markello RD et al.	—	2018	→
Self-administration of the synthetic cathinone MDPV enhances reward function via a nicotinic receptor dependent mechanism.	Geste JR et al.	—	2018	→
Sensory Ecology of Predator-Induced Phenotypic Plasticity.	Weiss LC	—	2018	→
Specific Basal Forebrain-Cortical Cholinergic Circuits Coordinate Cognitive Operations.	Záborszky L et al.	—	2018	→
Spinalization and locomotor training differentially affect muscarinic acetylcholine receptor type 2 abutting on α-motoneurons innervating the ankle extensor and flexor muscles.	Więckowska A et al.	—	2018	→
Stress-induced brain activation: buffering role of social behavior and neuronal nicotinic receptors.	Nosjean A et al.	—	2018	→
The Meningeal Lymphatic System: A New Player in Neurophysiology.	Da Mesquita S et al.	—	2018	→
Toxic Effect of Cigarette Smoke on Brainstem Nicotinic Receptor Expression: Primary Cause of Sudden Unexplained Perinatal Death.	Lavezzi AM	—	2018	→
Treatment of obstructive sleep apnoea-hypopnea syndrome by mandible advanced device reduced neuron apoptosis in frontal cortex of rabbits.	Lu HY et al.	—	2018	→
Anticholinergic activity in the nervous system: Consequences for visuomotor function.	Naicker P et al.	—	2017	→
Chaperone-Mediated Regulation of Choline Acetyltransferase Protein Stability and Activity by HSC/HSP70, HSP90, and p97/VCP.	Morey TM et al.	—	2017	→
Cholinergic circuits in cognitive flexibility.	Prado VF et al.	—	2017	→
Cholinergic/glutamatergic co-transmission in striatal cholinergic interneurons: new mechanisms regulating striatal computation.	Kljakic O et al.	—	2017	→
Cholinergic Modulation of Cortical Microcircuits Is Layer-Specific: Evidence from Rodent, Monkey and Human Brain.	Obermayer J et al.	—	2017	→
Cholinergic modulation of the hippocampal region and memory function.	Haam J et al.	—	2017	→
Cholinergic neurons in the dorsomedial hypothalamus regulate food intake.	Jeong JH et al.	—	2017	→
Cholinergic Projections to the Substantia Nigra Pars Reticulata Inhibit Dopamine Modulation of Basal Ganglia through the M<sub>4</sub> Muscarinic Receptor.	Moehle MS et al.	—	2017	→
Cholinergic Receptor Binding in Alzheimer Disease and Healthy Aging: Assessment In Vivo with Positron Emission Tomography Imaging.	Sultzer DL et al.	—	2017	→
Developmental specification of forebrain cholinergic neurons.	Allaway KC et al.	—	2017	→
Down-regulation of cholinergic signaling in the habenula induces anhedonia-like behavior.	Han S et al.	—	2017	→
Drugs Interfering with Muscarinic Acetylcholine Receptors and Their Effects on Place Navigation.	Svoboda J et al.	—	2017	→
Dynamic changes in murine forebrain miR-211 expression associate with cholinergic imbalances and epileptiform activity.	Bekenstein U et al.	—	2017	→
Electrophysiological properties of basal forebrain cholinergic neurons identified by genetic and optogenetic tagging.	López-Hernández GY et al.	—	2017	→
Enhanced Gamma Activity and Cross-Frequency Interaction of Resting-State Electroencephalographic Oscillations in Patients with Alzheimer's Disease.	Wang J et al.	—	2017	→
Environmental Presence of Hexavalent but Not Trivalent Chromium Causes Neurotoxicity in Exposed Drosophila melanogaster.	Singh P et al.	—	2017	→
Fast Cholinergic Synaptic Transmission in the Mammalian Central Nervous System.	Beierlein M	—	2017	→
Functional networks and network perturbations in rodents.	Chuang KH et al.	—	2017	→
<i>Artemisia scoparia</i> attenuates amyloid β accumulation and tau hyperphosphorylation in spontaneously hypertensive rats.	Promyo K et al.	—	2017	→
Impact of ageing on postsynaptic neuronal nicotinic neurotransmission in auditory thalamus.	Sottile SY et al.	—	2017	→
Impairments of spatial memory in an Alzheimer's disease model via degeneration of hippocampal cholinergic synapses.	Zhu H et al.	—	2017	→
Label-free Imaging of Neurotransmitter Acetylcholine at Neuromuscular Junctions with Stimulated Raman Scattering.	Fu D et al.	—	2017	→
Localization of glutamatergic, GABAergic, and cholinergic neurons in the brain of the African cichlid fish, Astatotilapia burtoni.	Maruska KP et al.	—	2017	→
Maternal Choline Supplementation Modulates Placental Nutrient Transport and Metabolism in Late Gestation of Mouse Pregnancy.	Kwan STC et al.	—	2017	→
Medications influencing central cholinergic neurotransmission affect saccadic and smooth pursuit eye movements in healthy young adults.	Naicker P et al.	—	2017	→
Medications influencing central cholinergic pathways affect fixation stability, saccadic response time and associated eye movement dynamics during a temporally-cued visual reaction time task.	Naicker P et al.	—	2017	→
Metabolic, Epigenetic, and Transgenerational Effects of Gut Bacterial Choline Consumption.	Romano KA et al.	—	2017	→
Metformin Attenuates Aβ Pathology Mediated Through Levamisole Sensitive Nicotinic Acetylcholine Receptors in a C. elegans Model of Alzheimer's Disease.	Ahmad W et al.	—	2017	→
Modulation of Hippocampal Circuits by Muscarinic and Nicotinic Receptors.	Dannenberg H et al.	—	2017	→
Molecular and Cellular Mechanisms of Rapid-Acting Antidepressants Ketamine and Scopolamine.	Wohleb ES et al.	—	2017	→
Neural regulation of immunity: molecular mechanisms and clinical translation.	Pavlov VA et al.	—	2017	→
Neurotransmission systems in Parkinson's disease.	Sanjari Moghaddam H et al.	—	2017	→
[Optically dissecting brain nicotinic receptor function with photo-controllable designer receptors].	Durand-de Cuttoli R et al.	—	2017	→
Personalized genetics of the cholinergic blockade of neuroinflammation.	Simchovitz A et al.	—	2017	→
Physiological and pathological processes of synaptic plasticity and memory in drug discovery: Do not forget the dose-response curve.	Prickaerts J et al.	—	2017	→
Plasticity in Brainstem Mechanisms of Pain Modulation by Nicotinic Acetylcholine Receptors in the Rat.	Jareczek FJ et al.	—	2017	→
Progression of subcortical atrophy in mild Parkinson's disease and its impact on cognition.	Foo H et al.	—	2017	→
Relationship between the changes in M1 excitability after motor learning and arousal state as assessed by short-latency afferent inhibition.	Koizume Y et al.	—	2017	→
Resolution of inflammation pathways in preeclampsia-a narrative review.	Perucci LO et al.	—	2017	→
Selective Activation of Basal Forebrain Cholinergic Neurons Attenuates Polymicrobial Sepsis-Induced Inflammation via the Cholinergic Anti-Inflammatory Pathway.	Zhai Q et al.	—	2017	→
Synapses in the spotlight with synthetic optogenetics.	Berlin S et al.	—	2017	→
Targeting neuronal dysfunction in schizophrenia with nicotine: Evidence from neurophysiology to neuroimaging.	Smucny J et al.	—	2017	→
The fate of the brain cholinergic neurons in neurodegenerative diseases.	Pepeu G et al.	—	2017	→
The Obesity-Impulsivity Axis: Potential Metabolic Interventions in Chronic Psychiatric Patients.	Sfera A et al.	—	2017	→
Therapeutics of Neurotransmitters in Alzheimer's Disease.	Kandimalla R et al.	—	2017	→
[The role of central cholinergic system in epilepsy].	Wang Y et al.	—	2017	→
Unravelling the Link Between Prenatal Stress, Dopamine and Substance Use Disorder.	Pastor V et al.	—	2017	→
α4β2<sup>∗</sup> nicotinic receptors stimulate GABA release onto fast-spiking cells in layer V of mouse prefrontal (Fr2) cortex.	Aracri P et al.	—	2017	→
Acetylcholine modulates human working memory and subsequent familiarity based recognition via alpha oscillations.	Eckart C et al.	—	2016	→
A cholinergic basal forebrain feeding circuit modulates appetite suppression.	Herman AM et al.	—	2016	→
A SLM2 Feedback Pathway Controls Cortical Network Activity and Mouse Behavior.	Ehrmann I et al.	—	2016	→
Attention and the Cholinergic System: Relevance to Schizophrenia.	Lustig C et al.	—	2016	→
Basal Forebrain Cholinergic Circuits and Signaling in Cognition and Cognitive Decline.	Ballinger EC et al.	—	2016	→
Central cholinergic pathway involvement in the regulation of pupil diameter, blink rate and cognitive function.	Naicker P et al.	—	2016	→
Cholinergic Signaling Controls Conditioned Fear Behaviors and Enhances Plasticity of Cortical-Amygdala Circuits.	Jiang L et al.	—	2016	→
Chronic Nonmodulated Microwave Radiations in Mice Produce Anxiety-like and Depression-like Behaviours and Calcium- and NO-related Biochemical Changes in the Brain.	Kumar M et al.	—	2016	→
Cortical cholinergic signaling controls the detection of cues.	Gritton HJ et al.	—	2016	→
Cotransmission of acetylcholine and GABA.	Granger AJ et al.	—	2016	→
Deficits in cholinergic neurotransmission and their clinical correlates in Parkinson's disease.	Perez-Lloret S et al.	—	2016	→
Differential modulation of GABAA and NMDA receptors by α7-nicotinic receptor desensitization in cultured rat hippocampal neurons.	Shen L et al.	—	2016	→
Electrophysiological Properties of CA1 Pyramidal Neurons along the Longitudinal Axis of the Mouse Hippocampus.	Milior G et al.	—	2016	→
Enhanced ubiquitination and proteasomal degradation of catalytically deficient human choline acetyltransferase mutants.	Morey TM et al.	—	2016	→
Exposure to nicotine increases nicotinic acetylcholine receptor density in the reward pathway and binge ethanol consumption in C57BL/6J adolescent female mice.	Locker AR et al.	—	2016	→
Extracellular levels of ATP and acetylcholine during lithium-pilocarpine induced status epilepticus in rats.	Lietsche J et al.	—	2016	→
Fructus mume Ethanol Extract Prevents Inflammation and Normalizes the Septohippocampal Cholinergic System in a Rat Model of Chronic Cerebral Hypoperfusion.	Kim MS et al.	—	2016	→
GABA interneurons mediate the rapid antidepressant-like effects of scopolamine.	Wohleb ES et al.	—	2016	→
Graphene-based materials for tissue engineering.	Shin SR et al.	—	2016	→
Imaging of cerebral α4β2* nicotinic acetylcholine receptors with (-)-[(18)F]Flubatine PET: Implementation of bolus plus constant infusion and sensitivity to acetylcholine in human brain.	Hillmer AT et al.	—	2016	→
Intensified vmPFC surveillance over PTSS under perturbed microRNA-608/AChE interaction.	Lin T et al.	—	2016	→
Knowledge About Sounds-Context-Specific Meaning Differently Activates Cortical Hemispheres, Auditory Cortical Fields, and Layers in House Mice.	Geissler DB et al.	—	2016	→
Loss of MeCP2 in cholinergic neurons causes part of RTT-like phenotypes via α7 receptor in hippocampus.	Zhang Y et al.	—	2016	→
Multiple Nicotinic Acetylcholine Receptor Subtypes in the Mouse Amygdala Regulate Affective Behaviors and Response to Social Stress.	Mineur YS et al.	—	2016	→
Pharmacotherapies for Parkinson's disease symptoms related to cholinergic degeneration.	Perez-Lloret S et al.	—	2016	→
Potential roles of cholinergic modulation in the neural coding of location and movement speed.	Dannenberg H et al.	—	2016	→
Quantitative mass spectrometry imaging of small-molecule neurotransmitters in rat brain tissue sections using nanospray desorption electrospray ionization.	Bergman HM et al.	—	2016	→
Retinal co-mediator acetylcholine evokes muscarinic inhibition of recurrent excitation in frog tectum column.	Baginskas A et al.	—	2016	→
Selectivity of Neuromodulatory Projections from the Basal Forebrain and Locus Ceruleus to Primary Sensory Cortices.	Kim JH et al.	—	2016	→
The association of serum choline with linear growth failure in young children from rural Malawi.	Semba RD et al.	—	2016	→
The cholinergic system in the cerebellum: from structure to function.	Zhang C et al.	—	2016	→
The principle of conformational signaling.	Tompa P	—	2016	→
Zebrafish Get Connected: Investigating Neurotransmission Targets and Alterations in Chemical Toxicity.	Horzmann KA et al.	—	2016	→
A cellular and regulatory map of the cholinergic nervous system of C. elegans.	Pereira L et al.	—	2015	→
An essential role of acetylcholine-glutamate synergy at habenular synapses in nicotine dependence.	Frahm S et al.	—	2015	→
Apathy Treatment in Alzheimer's Disease: Interim Results of the ASCOMALVA Trial.	Rea R et al.	—	2015	→
A Special Extract of Bacopa monnieri (CDRI-08) Restores Learning and Memory by Upregulating Expression of the NMDA Receptor Subunit GluN2B in the Brain of Scopolamine-Induced Amnesic Mice.	Rai R et al.	—	2015	→
Checks and balances on cholinergic signaling in brain and body function.	Soreq H	—	2015	→
Cholinergic afferent stimulation induces axonal function plasticity in adult hippocampal granule cells.	Martinello K et al.	—	2015	→
Corelease of acetylcholine and GABA from cholinergic forebrain neurons.	Saunders A et al.	—	2015	→
Crystallization scale purification of α7 nicotinic acetylcholine receptor from mammalian cells using a BacMam expression system.	Cheng H et al.	—	2015	→
Divergent brain functional network alterations in dementia with Lewy bodies and Alzheimer's disease.	Peraza LR et al.	—	2015	→
Dopamine is a key regulator in the signalling pathway underlying predator-induced defences in Daphnia.	Weiss LC et al.	—	2015	→
Early Life Stress, Nicotinic Acetylcholine Receptors and Alcohol Use Disorders.	Holgate JY et al.	—	2015	→
Exploring the Validity of Valproic Acid Animal Model of Autism.	Mabunga DF et al.	—	2015	→
Fear and C-reactive protein cosynergize annual pulse increases in healthy adults.	Shenhar-Tsarfaty S et al.	—	2015	→
Fluoride and aluminium disturb neuronal morphology, transport functions, cholinesterase, lysosomal and cell cycle activities.	Akinrinade ID et al.	—	2015	→
Identification and characterization of ML352: a novel, noncompetitive inhibitor of the presynaptic choline transporter.	Ennis EA et al.	—	2015	→
Ion channels gated by acetylcholine and serotonin: structures, biology, and drug discovery.	Wu ZS et al.	—	2015	→
Mood and anxiety regulation by nicotinic acetylcholine receptors: A potential pathway to modulate aggression and related behavioral states.	Picciotto MR et al.	—	2015	→
Nicotine and ethanol co-use in Long-Evans rats: Stimulatory effects of perinatal exposure to a fat-rich diet.	Karatayev O et al.	—	2015	→
Pesticide exposure during pregnancy, like nicotine, affects the brainstem α7 nicotinic acetylcholine receptor expression, increasing the risk of sudden unexplained perinatal death.	Lavezzi AM et al.	—	2015	→
Potentiation of Neuronal Nicotinic Receptors by 17β-Estradiol: Roles of the Carboxy-Terminal and the Amino-Terminal Extracellular Domains.	Jin X et al.	—	2015	→
Reduction of Aggressive Episodes After Repeated Transdermal Nicotine Administration in a Hospitalized Adolescent with Autism Spectrum Disorder.	Van Schalkwyk GI et al.	—	2015	→
Repetition priming and cortical arousal in healthy aging and Alzheimer's disease.	Kane AE et al.	—	2015	→
Role of α7 nicotinic receptor in the immune system and intracellular signaling pathways.	Zdanowski R et al.	—	2015	→
Scopolamine and amphetamine produce similar decision-making deficits on a rat gambling task via independent pathways.	Silveira MM et al.	—	2015	→
Simultaneous measurement of cholinergic tone and neuronal network dynamics in vivo in the rat brain using a novel choline oxidase based electrochemical biosensor.	Santos RM et al.	—	2015	→
Sleep and plasticity in schizophrenia.	Sprecher KE et al.	—	2015	→
Structure of neuronal nicotinic receptors.	Fasoli F et al.	—	2015	→
Suitability of Nicotinic Acetylcholine Receptor α7 and Muscarinic Acetylcholine Receptor 3 Antibodies for Immune Detection: Evaluation in Murine Skin.	Rommel FR et al.	—	2015	→
Targeted pharmacological treatment of autism spectrum disorders: fragile X and Rett syndromes.	Wang H et al.	—	2015	→
The M-current contributes to high threshold membrane potential oscillations in a cell type-specific way in the pedunculopontine nucleus of mice.	Bordas C et al.	—	2015	→
Therapeutic hypothermia achieves neuroprotection via a decrease in acetylcholine with a concurrent increase in carnitine in the neonatal hypoxia-ischemia.	Takenouchi T et al.	—	2015	→
The twin drug approach for novel nicotinic acetylcholine receptor ligands.	Tomassoli I et al.	—	2015	→
Unmasking Proteolytic Activity for Adult Visual Cortex Plasticity by the Removal of Lynx1.	Bukhari N et al.	—	2015	→
Acute stress in adulthood impoverishes social choices and triggers aggressiveness in preclinical models.	Nosjean A et al.	—	2014	→
A four-diode full-wave ionic current rectifier based on bipolar membranes: overcoming the limit of electrode capacity.	Gabrielsson EO et al.	—	2014	→
Altered acetylcholine release in the hippocampus of dystrophin-deficient mice.	Parames SF et al.	—	2014	→
An Investigation of the Late Excitatory Potentials in the Hand following Transcranial Magnetic Stimulation in Early Alzheimer's Disease.	Balla C et al.	—	2014	→
Cholinergic modulation of large-conductance calcium-activated potassium channels regulates synaptic strength and spine calcium in cartwheel cells of the dorsal cochlear nucleus.	He S et al.	—	2014	→
Cholinergic modulation of the medial prefrontal cortex: the role of nicotinic receptors in attention and regulation of neuronal activity.	Bloem B et al.	—	2014	→
Curtailing effect of awakening on visual responses of cortical neurons by cholinergic activation of inhibitory circuits.	Kimura R et al.	—	2014	→
Deterministic functions of cortical acetylcholine.	Sarter M et al.	—	2014	→
Disposed to distraction: genetic variation in the cholinergic system influences distractibility but not time-on-task effects.	Berry AS et al.	—	2014	→
Hippocampal changes produced by overexpression of the human CHRNA5/A3/B4 gene cluster may underlie cognitive deficits rescued by nicotine in transgenic mice.	Molas S et al.	—	2014	→
Illuminating the role of cholinergic signaling in circuits of attention and emotionally salient behaviors.	Luchicchi A et al.	—	2014	→
Mechanisms underlying desynchronization of cholinergic-evoked thalamic network activity.	Pita-Almenar JD et al.	—	2014	→
Modulation of neuronal microcircuit activities within the medial prefrontal cortex by mGluR5 positive allosteric modulator.	Pollard M et al.	—	2014	→
Molecules and circuits involved in nicotine addiction: The many faces of smoking.	Picciotto MR et al.	—	2014	→
Neuromodulation by acetylcholine: examples from schizophrenia and depression.	Higley MJ et al.	—	2014	→
Neuromodulation of neurons and synapses.	Nadim F et al.	—	2014	→
Neuron-glia networks: integral gear of brain function.	Perea G et al.	—	2014	→
Nicotinic acetylcholine receptor density in cognitively intact subjects at an early stage of Parkinson's disease.	Isaias IU et al.	—	2014	→
Optogenetic studies of nicotinic contributions to cholinergic signaling in the central nervous system.	Jiang L et al.	—	2014	→
Parent-of-origin genetic background affects the transcriptional levels of circadian and neuronal plasticity genes following sleep loss.	Tinarelli F et al.	—	2014	→
Preclinical pharmacology of amphetamine: implications for the treatment of neuropsychiatric disorders.	Hutson PH et al.	—	2014	→
Role of nicotinic acetylcholine receptors in regulating dopamine neuron activity.	Faure P et al.	—	2014	→
Subchronic atrazine exposure changes defensive behaviour profile and disrupts brain acetylcholinesterase activity of zebrafish.	Schmidel AJ et al.	—	2014	→
Subchronic treatment of donepezil rescues impaired social, hyperactive, and stereotypic behavior in valproic acid-induced animal model of autism.	Kim JW et al.	—	2014	→
Thalamic neuromodulation and its implications for executive networks.	Varela C	—	2014	→
The contribution of acetylcholine and dopamine to subprocesses of visual working memory--what patients with amnestic mild cognitive impairment and Parkinson׳s disease can tell us.	Blatt J et al.	—	2014	→
The novel α7β2-nicotinic acetylcholine receptor subtype is expressed in mouse and human basal forebrain: biochemical and pharmacological characterization.	Moretti M et al.	—	2014	→
The role of nicotinic receptors in shaping and functioning of the glutamatergic system: a window into cognitive pathology.	Molas S et al.	—	2014	→
Topographic mapping between basal forebrain cholinergic neurons and the medial prefrontal cortex in mice.	Bloem B et al.	—	2014	→
A positive relationship between harm avoidance and brain nicotinic acetylcholine receptor availability.	Storage S et al.	—	2013	→
Biogenesis, trafficking and up-regulation of nicotinic ACh receptors.	Colombo SF et al.	—	2013	→
ChAT-ChR2-EYFP mice have enhanced motor endurance but show deficits in attention and several additional cognitive domains.	Kolisnyk B et al.	—	2013	→
Cholinergic signaling in the hippocampus regulates social stress resilience and anxiety- and depression-like behavior.	Mineur YS et al.	—	2013	→
Effect of olanzapine on scopolamine induced deficits in differential reinforcement of low rate 72s (DRL-72s) schedule in rats: involvement of the serotonergic receptors in restoring the deficits.	Jayarajan P et al.	—	2013	→
Extrasynaptic muscarinic acetylcholine receptors on neuronal cell bodies regulate presynaptic function in Caenorhabditis elegans.	Chan JP et al.	—	2013	→
Formation and reverberation of sequential neural activity patterns evoked by sensory stimulation are enhanced during cortical desynchronization.	Bermudez Contreras EJ et al.	—	2013	→
Genetic and neurophysiological correlates of the age of onset of alcohol use disorders in adolescents and young adults.	Chorlian DB et al.	—	2013	→
High-affinity nicotinic acetylcholine receptor expression and trafficking abnormalities in psychiatric illness.	Lewis AS et al.	—	2013	→
Medial habenula output circuit mediated by α5 nicotinic receptor-expressing GABAergic neurons in the interpeduncular nucleus.	Hsu YW et al.	—	2013	→
Morphine dependence and withdrawal induced changes in cholinergic signaling.	Neugebauer NM et al.	—	2013	→
Neuroligin 2 is expressed in synapses established by cholinergic cells in the mouse brain.	Takács VT et al.	—	2013	→
Nicotinic acetylcholine receptors controlling attention: behavior, circuits and sensitivity to disruption by nicotine.	Poorthuis RB et al.	—	2013	→
Nicotinic modulation of intrinsic brain networks in schizophrenia.	Smucny J et al.	—	2013	→
Phasic nicotinic potentiation of frog retinotectal transmission facilitates eliciting of higher activity level of the tectum column.	Baginskas A et al.	—	2013	→
Role of attention in the generation and modulation of tinnitus.	Roberts LE et al.	—	2013	→
Subthreshold mechanisms underlying state-dependent modulation of visual responses.	Bennett C et al.	—	2013	→
The 3,7-diazabicyclo[3.3.1]nonane scaffold for subtype selective nicotinic acetylcholine receptor (nAChR) ligands. Part 1: the influence of different hydrogen bond acceptor systems on alkyl and (hetero)aryl substituents.	Eibl C et al.	—	2013	→
The functional tumor necrosis factor-α (308A/G) polymorphism modulates attentional selection in elderly individuals.	Gajewski PD et al.	—	2013	→
Universal organization of resting brain activity at the thermodynamic critical point.	Yu S et al.	—	2013	→