A gene atlas of the mouse and human protein-encoding transcriptomes.
paper
Cited
Public
Unavailable
- Authors
- Su, Andrew I; Wiltshire, Tim; Batalov, Serge; Lapp, Hilmar; Ching, Keith A; Block, David; Zhang, Jie; Soden, Richard; Hayakawa, Mimi; Kreiman, Gabriel; Cooke, Michael P; Walker, John R; Hogenesch, John B
- Year
- 2004
- Journal
- Proceedings of the National Academy of Sciences of the United States of America
- PMID
- 15075390
- DOI
- 10.1073/pnas.0400782101
- PMCID
- PMC395923
The tissue-specific pattern of mRNA expression can indicate important clues about gene function. High-density oligonucleotide arrays offer the opportunity to examine patterns of gene expression on a genome scale. Toward this end, we have designed custom arrays that interrogate the expression of the vast majority of protein-encoding human and mouse genes and have used them to profile a panel of 79 human and 61 mouse tissues. The resulting data set provides the expression patterns for thousands of predicted genes, as well as known and poorly characterized genes, from mice and humans. We have explored this data set for global trends in gene expression, evaluated commonly used lines of evidence in gene prediction methodologies, and investigated patterns indicative of chromosomal organization of transcription. We describe hundreds of regions of correlated transcription and show that some are subject to both tissue and parental allele-specific expression, suggesting a link between spatial expression and imprinting.
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| A reference map of sphingolipids in murine tissues. | Muralidharan S et al. | β | 2021 | β |
| A Review of Oxidative Stress Products and Related Genes in Early Alzheimer's Disease. | Cioffi F et al. | β | 2021 | β |
| Arginine Metabolism and Its Potential in Treatment of Colorectal Cancer. | Du T et al. | β | 2021 | β |
| Associations between <i>LMO1</i> gene polymorphisms and central nervous system tumor susceptibility. | Lin H et al. | β | 2021 | β |
| Aurora B kinase: a potential drug target for cancer therapy. | Ahmed A et al. | β | 2021 | β |
| Circulating tumor cells detected with a microcavity array predict clinical outcome in hepatocellular carcinoma. | Takahashi K et al. | β | 2021 | β |
| Clinical evaluation of urinary liver-type fatty acid-binding protein for the diagnosis of renal diseases in dogs. | Takashima S et al. | β | 2021 | β |
| Comprehensive co-expression analysis reveals TMC8 as a prognostic immune-associated gene in head and neck squamous cancer. | Lin B et al. | β | 2021 | β |
| Connectivity Map Analysis of a Single-Cell RNA-Sequencing -Derived Transcriptional Signature of mTOR Signaling. | Al Mahi N et al. | β | 2021 | β |
| Conveyance of cortical pacing for parkinsonian tremor-like hyperkinetic behavior by subthalamic dysrhythmia. | Huang CS et al. | β | 2021 | β |
| COVID-19 and central nervous system interplay: A big picture beyond clinical manifestation. | Chaudhury SS et al. | β | 2021 | β |
| Database and Statistical Analyses of Transcription Factor Binding Sites in the Non-Coding Control Region of JC Virus. | Nakamichi K et al. | β | 2021 | β |
| Defining the functional divergence of orthologous genes between human and mouse in the context of miRNA regulation. | Cui C et al. | β | 2021 | β |
| DGLinker: flexible knowledge-graph prediction of disease-gene associations. | Hu J et al. | β | 2021 | β |
| Differential and longitudinal immune gene patterns associated with reprogrammed microenvironment and viral mimicry in response to neoadjuvant radiotherapy in rectal cancer. | Wilkins A et al. | β | 2021 | β |
| Disease Modeling and Disease Gene Discovery in Cardiomyopathies: A Molecular Study of Induced Pluripotent Stem Cell Generated Cardiomyocytes. | Kumar S et al. | β | 2021 | β |
| ECSIT is a critical limiting factor for cardiac function. | Xu L et al. | β | 2021 | β |
| Eutopic endometrium from women with endometriosis and chlamydial endometritis share immunological cell types and DNA repair imbalance: A transcriptome meta-analytical perspective. | Poli-Neto OB et al. | β | 2021 | β |
| Genome-wide rare variant score associates with morphological subtypes of autism spectrum disorder | Chan AJ et al. | β | 2021 | β |
| Glucocorticoids Elevate <i>Pseudomonas aeruginosa</i> Binding to Airway Epithelium by Upregulating Syndecan-1 Expression. | Liu D et al. | β | 2021 | β |
| Glutamine deficiency induces lipolysis in adipocytes. | Okuro K et al. | β | 2021 | β |
| Gravitational Force-Induced 3D Chromosomal Conformational Changes Are Associated with Rapid Transcriptional Response in Human T Cells. | Vahlensieck C et al. | β | 2021 | β |
| Identification of core gene in obese type 2 diabetes patients using bioinformatics analysis. | Dong Z et al. | β | 2021 | β |
| IL-4-BATF signaling directly modulates IL-9 producing mucosal mast cell (MMC9) function in experimental food allergy. | Tomar S et al. | β | 2021 | β |
| Integration of metabolomics and transcriptomics reveals convergent pathways driving radiation-induced salivary gland dysfunction. | Meeks L et al. | β | 2021 | β |
| Integrative transcriptomic analysis of tissue-specific metabolic crosstalk after myocardial infarction. | Arif M et al. | β | 2021 | β |
| Large-scale plasma proteomics can reveal distinct endotypes in chronic obstructive pulmonary disease and severe asthma. | Suzuki M et al. | β | 2021 | β |
| MAIT cells regulate NK cell-mediated tumor immunity. | Petley EV et al. | β | 2021 | β |
| Melanoma Cell Intrinsic GABA<sub>A</sub> Receptor Enhancement Potentiates Radiation and Immune Checkpoint Inhibitor Response by Promoting Direct and T Cell-Mediated Antitumor Activity. | Pomeranz Krummel DA et al. | β | 2021 | β |
| Molecular Analysis of <i>14-3-3</i> Genes in <i>Citrus sinensis</i> and Their Responses to Different Stresses. | Lyu S et al. | β | 2021 | β |
| Neurological and psychiatric effects of hepatitis C virus infection. | Faccioli J et al. | β | 2021 | β |
| No Expression Divergence despite Transcriptional Interference between Nested Protein-Coding Genes in Mammals. | Assis R | β | 2021 | β |
| Nonalcoholic steatohepatitis: the role of peroxisome proliferator-activated receptors. | Francque S et al. | β | 2021 | β |
| Openness weighted association studies: leveraging personal genome information to prioritize non-coding variants. | Song S et al. | β | 2021 | β |
| Parasympathetic neural activity and the reciprocal regulation of innate antiviral and inflammatory genes in the human immune system. | Sloan RP et al. | β | 2021 | β |
| Pathophysiological Implications of Imbalances in Fibroblast Growth Factor 23 in the Development of Diabetes. | Donate-Correa J et al. | β | 2021 | β |
| PAX7 promotes CD49f-positive dairy goat spermatogonial stem cells' self-renewal. | Du X et al. | β | 2021 | β |
| PIGG variant pathogenicity assessment reveals characteristic features within 19 families. | Tremblay-LaganiΓ¨re C et al. | β | 2021 | β |
| Predictive Markers of Immunogenicity and Efficacy for Human Vaccines. | Van Tilbeurgh M et al. | β | 2021 | β |
| Proteotyping of knockout mouse strains reveals sex- and strain-specific signatures in blood plasma. | Mohammed Y et al. | β | 2021 | β |
| PrP <i><sup>C</sup></i> as a Transducer of Physiological and Pathological Signals. | Panes JD et al. | β | 2021 | β |
| RNA-binding protein 39: a promising therapeutic target for cancer. | Xu C et al. | β | 2021 | β |
| Roles of long nonβcoding RNA in osteoarthritis (Review). | Wang J et al. | β | 2021 | β |
| Roles of nuclear receptors in hepatic stellate cells. | Pu S et al. | β | 2021 | β |
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| Single-cell RNA-seq reveals a concomitant delay in differentiation and cell cycle of aged hematopoietic stem cells. | HΓ©rault L et al. | β | 2021 | β |
| Small Molecular Inhibitors Block TRPM4 Currents in Prostate Cancer Cells, with Limited Impact on Cancer Hallmark Functions. | BorgstrΓΆm A et al. | β | 2021 | β |
| Smc3 dosage regulates B cell transit through germinal centers and restricts their malignant transformation. | Rivas MA et al. | β | 2021 | β |
| Systematic detection of brain protein-coding genes under positive selection during primate evolution and their roles in cognition. | Dumas G et al. | β | 2021 | β |
| Targeting NSD2-mediated SRC-3 liquid-liquid phase separation sensitizes bortezomib treatment in multiple myeloma. | Liu J et al. | β | 2021 | β |
| TGF-Ξ²1 and IL-17A comediate the protumor phenotype of neutrophils to regulate the epithelial-mesenchymal transition in oral squamous cell carcinoma. | Yu T et al. | β | 2021 | β |
| The amniotic fluid cell-free transcriptome in spontaneous preterm labor. | Bhatti G et al. | β | 2021 | β |
| The Distinct Immune Nature of the Fetal Inflammatory Response Syndrome Type I and Type II. | Para R et al. | β | 2021 | β |
| The Gene Expression Deconvolution Interactive Tool (GEDIT): accurate cell type quantification from gene expression data. | Nadel BB et al. | β | 2021 | β |
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| The inhibitive effects of proteasome inhibitor MG-132 on pterygium fibroblasts in vitro and the potential key regulators involved. | Zhao D et al. | β | 2021 | β |
| The renin-angiotensin system in COVID-19: Why ACE2 targeting by coronaviruses produces higher mortality in elderly hypertensive patients? | Kurbel S | β | 2021 | β |
| The resolvin D1 receptor GPR32 transduces inflammation resolution and atheroprotection. | Arnardottir H et al. | β | 2021 | β |
| Thrombomodulin is associated with increased mortality and organ failure in mechanically ventilated children with acute respiratory failure: biomarker analysis from a multicenter randomized controlled trial. | Monteiro ACC et al. | β | 2021 | β |
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| Transcriptome Atlas of 16 Donkey Tissues. | Wang Y et al. | β | 2021 | β |
| Triangulating Molecular Evidence to Prioritize Candidate Causal Genes at Established Atopic Dermatitis Loci. | Sobczyk MK et al. | β | 2021 | β |
| TRIM21 - A potential novel therapeutic target in cancer. | Alomari M | β | 2021 | β |
| Weighted Gene Co-Expression Network Analysis Identifies ANGPTL4 as a Key Regulator in Diabetic Cardiomyopathy <i>via</i> FAK/SIRT3/ROS Pathway in Cardiomyocyte. | Dai L et al. | β | 2021 | β |
| ACE2: Evidence of role as entry receptor for SARS-CoV-2 and implications in comorbidities. | Zamorano Cuervo N et al. | β | 2020 | β |
| A Cell- and Tissue-Specific Weakness of the Protein Homeostasis System Underlies Brain Vulnerability to Protein Aggregation. | Kundra R et al. | β | 2020 | β |
| Adaptive evolution of peptidoglycan recognition protein family regulates the innate signaling against microbial pathogens in vertebrates. | Ahmad HI et al. | β | 2020 | β |
| Adaptive selection in the evolution of programmed cell death-1 and its ligands in vertebrates. | Ahmad HI et al. | β | 2020 | β |
| Amniotic fluid cell-free transcriptome: a glimpse into fetal development and placental cellular dynamics during normal pregnancy. | Tarca AL et al. | β | 2020 | β |
| A novel splice variant expands the LAMC3-associated cortical phenotype to frontal only polymicrogyria and adult-onset epilepsy. | Kasper BS et al. | β | 2020 | β |
| Antimicrobial Synergy of a Ribonuclease and a Peptide Secreted by Human Cells. | Eller CH et al. | β | 2020 | β |
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| Brain structural connectome in relation to PRRT2 mutations in paroxysmal kinesigenic dyskinesia. | Li L et al. | β | 2020 | β |
| C1q/tumor necrosis factor-related protein-1 attenuates microglia autophagy and inflammatory response by regulating the Akt/mTOR pathway. | Wang H et al. | β | 2020 | β |
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| Clinical Application Potential of Small Molecules that Induce Brown Adipose Tissue Thermogenesis by Improving Fat Metabolism. | Lu KY et al. | β | 2020 | β |
| Deletion of Btg1 Induces Prmt1-Dependent Apoptosis and Increased Stemness in Shh-Type Medulloblastoma Cells Without Affecting Tumor Frequency. | Ceccarelli M et al. | β | 2020 | β |
| Differential expression of interferon-lambda receptor 1 splice variants determines the magnitude of the antiviral response induced by interferon-lambda 3 in human immune cells. | Santer DM et al. | β | 2020 | β |
| Differential regulation of the immune system in a brain-liver-fats organ network during short-term fasting. | Huang SSY et al. | β | 2020 | β |
| Endothelial Ribonuclease 1 in Cardiovascular and Systemic Inflammation. | Bedenbender K et al. | β | 2020 | β |
| Etiopathogenetic Mechanisms in Diverticular Disease of the Colon. | Camilleri M et al. | β | 2020 | β |
| Evaluation of the Performance of Lipidyzer Platform and Its Application in the Lipidomics Analysis in Mouse Heart and Liver. | Cao Z et al. | β | 2020 | β |
| FAM122A Inhibits Erythroid Differentiation through GATA1. | Chen J et al. | β | 2020 | β |
| Flow-CytometryΒ Platform for Intracellular Detection of FVIII in Blood Cells: A New Tool to Assess Gene Therapy Efficiency for Hemophilia A. | Elnaggar M et al. | β | 2020 | β |
| Genetic Factors of Nitric Oxide's System in Psychoneurologic Disorders. | Nasyrova RF et al. | β | 2020 | β |
| Genetic variants entail type 2 diabetes as an innate immune disorder. | Bandesh K et al. | β | 2020 | β |
| Heparanase is Involved in Leukocyte Migration. | Higashi N et al. | β | 2020 | β |
| Human Influenza Virus Hemagglutinins Contain Conserved Oligomannose N-Linked Glycans Allowing Potent Neutralization by Lectins. | Thompson AJ et al. | β | 2020 | β |
| Hypoxia Promotes Syndecan-3 Expression in the Tumor Microenvironment. | Prieto-FernΓ‘ndez E et al. | β | 2020 | β |
| Identification and characterization of c-raf from orange-spotted grouper (Epinephelus coioides). | Mo ZQ et al. | β | 2020 | β |
| IL-33 Is Essential for Adjuvant Effect of Hydroxypropyl-Ξ²-Cyclodexrin on the Protective Intranasal Influenza Vaccination. | Kobari S et al. | β | 2020 | β |
| <i>MCM2</i> and <i>NUSAP1</i> Are Potential Biomarkers for the Diagnosis and Prognosis of Pancreatic Cancer. | Deng Y et al. | β | 2020 | β |
| Inactive Rhomboid Protein 2 Mediates Intestinal Inflammation by Releasing Tumor Necrosis Factor-Ξ±. | Kim JH et al. | β | 2020 | β |
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| Investigating Pregnancy and Its Complications Using Circulating Cell-Free RNA in Women's Blood During Gestation. | Moufarrej MN et al. | β | 2020 | β |
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| Molecular Pharmacology of NRH:Quinone Oxidoreductase 2: A Detoxifying Enzyme Acting as an Undercover Toxifying Enzyme. | Janda E et al. | β | 2020 | β |
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| Novel eye genes systematically discovered through an integrated analysis of mouse transcriptomes and phenome. | Chiang CY et al. | β | 2020 | β |
| NPFF increases fusogenic proteins syncytin 1 and syncytin 2 via GCM1 in first trimester primary human cytotrophoblast cells. | Zhu H et al. | β | 2020 | β |
| Nuclear factor kappa B activation appears weaker in schizophrenia patients with high brain cytokines than in non-schizophrenic controls with high brain cytokines. | Murphy CE et al. | β | 2020 | β |
| Obesity Genomics and Metabolomics: a Nexus of Cardiometabolic Risk. | Regan JA et al. | β | 2020 | β |
| PGC-1Ξ²-expressing POMC neurons mediate the effect of leptin on thermoregulation in the mouse. | Delezie J et al. | β | 2020 | β |
| Phase Separation and Disorder-to-Order Transition of Human Brain Expressed X-Linked 3 (hBEX3) in the Presence of Small Fragments of tRNA. | do Amaral MJ et al. | β | 2020 | β |
| (Phospho)proteomic Profiling of Microsatellite Unstable CRC Cells Reveals Alterations in Nuclear Signaling and Cholesterol Metabolism Caused by Frameshift Mutation of NMD Regulator UPF3A. | Michalak M et al. | β | 2020 | β |
| Placenta-Specific Genes, Their Regulation During Villous Trophoblast Differentiation and Dysregulation in Preterm Preeclampsia. | Szilagyi A et al. | β | 2020 | β |
| Potential roles in cardiac physiology and pathology of the cation channel TRPV2 expressed in cardiac cells and cardiac macrophages: a mini-review. | Entin-Meer M et al. | β | 2020 | β |
| Profiling immunoglobulin repertoires across multiple human tissues using RNA sequencing. | Mandric I et al. | β | 2020 | β |
| Protein Kinase A Catalytic and Regulatory Subunits Interact Differently in Various Areas of Mouse Brain. | Mucignat-Caretta C et al. | β | 2020 | β |
| Recent advances in blood pressure research. | Mrowka R | β | 2020 | β |
| Regulation of the methylome in differentiation from adult stem cells may underpin vitamin D risk in MS. | Ong LTC et al. | β | 2020 | β |
| Renal expression and urinary excretion of liver-type fatty acid-binding protein in cats with renal disease. | Katayama M et al. | β | 2020 | β |
| Role of the Transcription Factor Yin Yang 1 and Its Selectively Identified Target Survivin in High-Grade B-Cells Non-Hodgkin Lymphomas: Potential Diagnostic and Therapeutic Targets. | Vivarelli S et al. | β | 2020 | β |
| Shared distal regulatory regions may contribute to the coordinated expression of human ribosomal protein genes. | Wang S et al. | β | 2020 | β |
| Shifts of Immune Cell Populations Differ in Response to Different Effectors of Beige Remodeling of Adipose Tissue. | Rabhi N et al. | β | 2020 | β |
| Single-Cell Transcriptomic Analysis Identifies a Unique Pulmonary Lymphangioleiomyomatosis Cell. | Guo M et al. | β | 2020 | β |
| Structural cells are key regulators of organ-specific immune responses. | Krausgruber T et al. | β | 2020 | β |
| Suppression of inflammatory genes expression in the injured host intestinal wall during Mesocestoides vogae tetrathyridium larvae migration. | Hayashi K et al. | β | 2020 | β |
| Systematic analysis of copy-number variations associated with early pregnancy loss. | Wang Y et al. | β | 2020 | β |
| Targeting aurora kinase B alleviates spinal microgliosis and neuropathic pain in a rat model of peripheral nerve injury. | Shen Y et al. | β | 2020 | β |
| Targeting Piezo1 unleashes innate immunity against cancer and infectious disease. | Aykut B et al. | β | 2020 | β |
| The glycosyltransferase EXTL2 promotes proteoglycan deposition and injurious neuroinflammation following demyelination. | Pu A et al. | β | 2020 | β |
| The Impact of DNA Methylation Dynamics on the Mutation Rate During Human Germline Development. | Zhou Y et al. | β | 2020 | β |
| The recurrent SETBP1 c.2608Gβ>βA, p.(Gly870Ser) variant in a patient with Schinzel-Giedion syndrome: an illustrative case of the utility of whole exome sequencing in a critically ill neonate. | Leone MP et al. | β | 2020 | β |
| The transcription factor C/EBPΞ² orchestrates dendritic cell maturation and functionality under homeostatic and malignant conditions. | Scholz F et al. | β | 2020 | β |
| Transcriptome meta-analysis reveals differences of immune profile between eutopic endometrium from stage I-II and III-IV endometriosis independently of hormonal milieu. | Poli-Neto OB et al. | β | 2020 | β |
| Transcriptomic features of trophoblast lineage cells derived from human induced pluripotent stem cells treated with BMP 4. | Tsuchida N et al. | β | 2020 | β |
| TRIM21-SERPINB5 aids GMPS repression to protect nasopharyngeal carcinoma cells from radiation-induced apoptosis. | Zhang P et al. | β | 2020 | β |
| Type 3 IP<sub>3</sub> receptors: The chameleon in cancer. | Rosa N et al. | β | 2020 | β |
| Understanding Calcium-Dependent Conformational Changes in S100A1 Protein: A Combination of Molecular Dynamics and Gene Expression Study in Skeletal Muscle. | Chaturvedi N et al. | β | 2020 | β |
| Whole-Genome Promoter Profiling of Plasma DNA Exhibits Diagnostic Value for Placenta-Origin Pregnancy Complications. | Guo Z et al. | β | 2020 | β |
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| A cross-talk between blood-cell neuroplasticity-related genes and environmental enrichment in working dogs. | Guelfi G et al. | β | 2019 | β |
| Analysis of a Sardinian Multiplex Family with Autism Spectrum Disorder Points to Post-Synaptic Density Gene Variants and Identifies <i>CAPG</i> as a Functionally Relevant Candidate Gene. | Bacchelli E et al. | β | 2019 | β |
| An Integrated Bioinformatics Analysis Repurposes an Antihelminthic Drug Niclosamide for Treating HMGA2-Overexpressing Human Colorectal Cancer. | Leung SW et al. | β | 2019 | β |
| A Novel Regulatory Axis, CHD1L-MicroRNA 486-Matrix Metalloproteinase 2, Controls Spermatogonial Stem Cell Properties. | Liu SS et al. | β | 2019 | β |
| Attenuation of doxorubicin-induced cardiotoxicity in a human in vitro cardiac model by the induction of the NRF-2 pathway. | Tomlinson L et al. | β | 2019 | β |
| Autosomal dominant nanophthalmos and high hyperopia associated with a C-terminal frameshift variant in <i>MYRF</i>. | Siggs OM et al. | β | 2019 | β |
| Both rare and common genetic variants contribute to autism in the Faroe Islands. | Leblond CS et al. | β | 2019 | β |
| CCN1 interlinks integrin and hippo pathway to autoregulate tip cell activity. | Park MH et al. | β | 2019 | β |
| CD73 expression in normal and pathological human hepatobiliopancreatic tissues. | Sciarra A et al. | β | 2019 | β |
| Characterization and analysis of the transcriptome in Gymnocypris selincuoensis on the Qinghai-Tibetan Plateau using single-molecule long-read sequencing and RNA-seq. | Feng X et al. | β | 2019 | β |
| Characterization of mRNA profiles of the exosome-like vesicles in porcine follicular fluid. | Matsuno Y et al. | β | 2019 | β |
| Circulating aryl hydrocarbon receptor-interacting protein (AIP) is independent of GH secretion. | Stojanovic M et al. | β | 2019 | β |
| Coagulant activity of recombinant human factor VII produced by lentiviral human F7 gene transfer in immortalized hepatocyte-like cell line. | Pongjantarasatian S et al. | β | 2019 | β |
| Comparative analysis of corrected tiger genome provides clues to its neuronal evolution. | Mittal P et al. | β | 2019 | β |
| Consequences of the Endogenous N-Glycosylation of Human Ribonuclease 1. | Ressler VT et al. | β | 2019 | β |
| CRISPR-mediated activation of a promoter or enhancer rescues obesity caused by haploinsufficiency. | Matharu N et al. | β | 2019 | β |
| Deletion of Adam6 in Mus musculus leads to male subfertility and deficits in sperm ascent into the oviduct. | Voronina VA et al. | β | 2019 | β |
| DENND5B Regulates Intestinal Triglyceride Absorption and Body Mass. | Gordon SM et al. | β | 2019 | β |
| Differences in Gene Expression in Older Compared With Younger Kidney Transplant Recipients. | Schaenman JM et al. | β | 2019 | β |
| Disruption of the Sensory System Affects Sterile Cutaneous Inflammation InΒ Vivo. | La Russa F et al. | β | 2019 | β |
| Drug repurposing for Alzheimer's disease based on transcriptional profiling of human iPSC-derived cortical neurons. | Williams G et al. | β | 2019 | β |
| Emerging role of SIRT3 in endothelial metabolism, angiogenesis, and cardiovascular disease. | He X et al. | β | 2019 | β |
| Enhanced histamine-induced itch in diacylglycerol kinase iota knockout mice. | Bartsch VB et al. | β | 2019 | β |
| Expression analysis of Rab11 during zebrafish embryonic development. | Zhang H et al. | β | 2019 | β |
| Expression of the Phosphatase Ppef2 Controls Survival and Function of CD8<sup>+</sup> Dendritic Cells. | Zwick M et al. | β | 2019 | β |
| Falling in love is associated with immune system gene regulation. | Murray DR et al. | β | 2019 | β |
| Fighting rheumatoid arthritis: Kv1.3 as a therapeutic target. | Serrano-AlbarrΓ‘s A et al. | β | 2019 | β |
| FKBP51 and FKBP12.6-Novel and tight interactors of Glomulin. | HΓ€hle A et al. | β | 2019 | β |
| Functional rare and low frequency variants in BLK and BANK1 contribute to human lupus. | Jiang SH et al. | β | 2019 | β |
| Gas6/TAM System: A Key Modulator of the Interplay between Inflammation and Fibrosis. | Bellan M et al. | β | 2019 | β |
| Genetic Influences on the Amount of Cell Death in the Neural Tube of BXD Mice Exposed to Acute Ethanol at Midgestation. | ThΓ©berge ET et al. | β | 2019 | β |
| Genomewide identification and analysis of heat-shock proteins 70/110 to reveal their potential functions in Chinese soft-shelled turtle <i>Pelodiscus sinensis</i>. | Liu T et al. | β | 2019 | β |
| GPR18 expression on PMNs as biomarker for outcome in patient with sepsis. | Zhang L et al. | β | 2019 | β |
| HLA class I-restricted T cell epitopes isolated and identified from myeloid leukemia cells. | Nyambura LW et al. | β | 2019 | β |
| Hsp70 Binds to the Androgen Receptor N-terminal Domain and Modulates the Receptor Function in Prostate Cancer Cells. | Dong J et al. | β | 2019 | β |
| Induction of human pluripotent stem cells into kidney tissues by synthetic mRNAs encoding transcription factors. | Hiratsuka K et al. | β | 2019 | β |
| Insights into the Signal Transduction Pathways of Mouse Lung Type II Cells Revealed by Transcription Factor Profiling in the Transcriptome. | Ramana CV | β | 2019 | β |
| Intrinsic expression of viperin regulates thermogenesis in adipose tissues. | Eom J et al. | β | 2019 | β |
| Melatonin protects mesenchymal stem cells from autophagy-mediated death under ischaemic ER-stress conditions by increasing prion protein expression. | Lee JH et al. | β | 2019 | β |
| Mineral absorption is an enriched pathway in a brain region of restless legs syndrome patients with reduced MEIS1 expression. | Sarayloo F et al. | β | 2019 | β |
| Minocycline inhibits PDGF-BB-induced human aortic smooth muscle cell proliferation and migration by reversing miR-221- and -222-mediated RECK suppression. | Higashi Y et al. | β | 2019 | β |
| Mitochondrial hypoxic stress induces widespread RNA editing by APOBEC3G in natural killer cells. | Sharma S et al. | β | 2019 | β |
| Molecular characterization and expression regulation of the factor-inhibiting HIF-1 (FIH-1) gene under hypoxic stress in bighead carp (Aristichthys nobilis). | Feng X et al. | β | 2019 | β |
| Mouse genome-wide association and systems genetics identifies Lhfp as a regulator of bone mass. | Mesner LD et al. | β | 2019 | β |
| Mouse screen reveals multiple new genes underlying mouse and human hearing loss. | Ingham NJ et al. | β | 2019 | β |
| Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility. | International Multiple Sclerosis Genetics Consortium | β | 2019 | β |
| Muscle xenografts reproduce key molecular features of facioscapulohumeral muscular dystrophy. | Mueller AL et al. | β | 2019 | β |
| Mutant hFGF23(A12D) stimulates osteoblast differentiation through FGFR3. | Tu Y et al. | β | 2019 | β |
| Novel Genetic Locus Influencing Retinal Venular Tortuosity Is Also Associated With Risk of Coronary Artery Disease. | Veluchamy A et al. | β | 2019 | β |
| Novel Y-Chromosome Long Non-Coding RNAs Expressed in Human Male CNS During Early Development. | Johansson MM et al. | β | 2019 | β |
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| Postmitotic cell longevity-associated genes: a transcriptional signature of postmitotic maintenance in neural tissues. | Castillo-Morales A et al. | β | 2019 | β |
| Postmortem brain tissue as an underutilized resource to study the molecular pathology of neuropsychiatric disorders across different ethnic populations. | Vornholt E et al. | β | 2019 | β |
| Pro-inflammatory immune cell gene expression during the third trimester of pregnancy is associated with shorter gestational length and lower birthweight. | Ross KM et al. | β | 2019 | β |
| Quantifying Gene Essentiality Based on the Context of Cellular Components. | Jia K et al. | β | 2019 | β |
| Quantitative Analysis of the Whole-Body Metabolic Fate of Branched-Chain Amino Acids. | Neinast MD et al. | β | 2019 | β |
| RAF Kinase Inhibitor Protein in Myeloid Leukemogenesis. | Zebisch A et al. | β | 2019 | β |
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| Structurally Conserved Primate LncRNAs Are Transiently Expressed during Human Cortical Differentiation and Influence Cell-Type-Specific Genes. | Field AR et al. | β | 2019 | β |
| System level characterization of small molecule drugs and their affected long noncoding RNAs. | Yang H et al. | β | 2019 | β |
| TAM receptors in cardiovascular disease. | McShane L et al. | β | 2019 | β |
| Targeting Histone Deacetylases in Myeloid Cells Inhibits Their Maturation and Inflammatory Function With Limited Effects on Atherosclerosis. | Luque-Martin R et al. | β | 2019 | β |
| Temporal changes in urinary excretion of liver-type fatty acid binding protein (L-FABP) in acute kidney injury model of domestic cats: a preliminary study. | Katayama M et al. | β | 2019 | β |
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| Selective Constraints on Coding Sequences of Nervous System Genes Are a Major Determinant of Duplicate Gene Retention in Vertebrates. | Roux J et al. | β | 2017 | β |
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| The Absence of NOD1 Enhances Killing of <i>Aspergillus fumigatus</i> Through Modulation of Dectin-1 Expression. | Gresnigt MS et al. | β | 2017 | β |
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| The Epithelial Sodium Channel Is a Modifier of the Long-Term Nonprogressive Phenotype Associated with F508del CFTR Mutations. | Agrawal PB et al. | β | 2017 | β |
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| Moving from capstones toward cornerstones: successes and challenges in applying systems biology to identify mechanisms of autism spectrum disorders. | Kopp N et al. | β | 2015 | β |
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| Single-Nucleotide Polymorphisms in Pig EPHX1 Gene are Associated with Pork Quality Traits. | Cho HR et al. | β | 2015 | β |
| SLC46A3 Is Required to Transport Catabolites of Noncleavable Antibody Maytansine Conjugates from the Lysosome to the Cytoplasm. | Hamblett KJ et al. | β | 2015 | β |
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| The draft genome sequence of the ferret (Mustela putorius furo) facilitates study of human respiratory disease. | Peng X et al. | β | 2014 | β |
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