Early onset problem behavior, young adult psychopathology, and contextual risk.
- Authors
- Keyes, Margaret A; Iacono, William G; McGue, Matt
- Year
- 2007
- Journal
- Twin research and human genetics : the official journal of the International Society for Twin Studies
- PMID
- 17539364
- DOI
- 10.1375/twin.10.1.45
A prospective study of 692 male twins was undertaken to investigate the relationships among early adolescent problem behavior, contextual risk, and disinhibitory psychopathology. Early adolescent problem behavior was assessed by the number of the following behaviors engaged in by the time of the age-14 assessment: (1) tobacco use, (2) alcohol use, (3) marijuana use, (4) other illicit drug use, (5) sexual intercourse, and (6) police contact. Contextual risk was assessed as a composite of measures of peer models, parent-offspring conflict, and academic engagement from the age-14 assessment. Disinhibitory psychopathology was assessed by symptoms of nicotine dependence, alcohol dependence, drug dependence, and adult antisocial behavior at the age-18 assessment. Early adolescent problem behavior and contextual risk were strongly correlated (r = .53) and both were strongly and independently associated with symptoms of disinhibitory psychopathology (r from .35 to .60). The association of early adolescent problem behavior with both contextual risk and disinhibitory psychopathology was mediated entirely by genetic factors while the association between contextual risk and disinhibitory psychopathology was mediated by both genetic and nonshared environmental factors. The results are discussed in the context of emerging research on the prognostic significance of early adolescent problem behavior for risk of adult psychopathology.
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| The onset of STI diagnosis through age 30: results from the Seattle Social Development Project Intervention. | Hill KG et al. | β | 2014 | β |
| Gene-environment correlation in the development of adolescent substance abuse: selection effects of child personality and mediation via contextual risk factors. | Hicks BM et al. | β | 2013 | β |
| Comorbid trajectories of tobacco and marijuana use as related to psychological outcomes. | Brook JS et al. | β | 2012 | β |
| Confluence of genes, environment, development, and behavior in a post Genome-Wide Association Study world. | Vrieze SI et al. | β | 2012 | β |
| Neurobehavioral disinhibition predicts initiation of substance use in children with prenatal cocaine exposure. | Lester BM et al. | β | 2012 | β |
| Levels of risk: maternal-, middle childhood-, and neighborhood-level predictors of adolescent disinhibitory behaviors from a longitudinal birth cohort in the United States. | Keyes KM et al. | β | 2011 | β |
| The social norms of birth cohorts and adolescent marijuana use in the United States, 1976-2007. | Keyes KM et al. | β | 2011 | β |
| Conduct disorder and psychosocial outcomes at age 30: early adult psychopathology as a potential mediator. | Olino TM et al. | β | 2010 | β |
| Disruptive behaviors and early sexual intercourse: The GAZEL Youth Study. | GalΓ©ra C et al. | β | 2010 | β |
| For distinguished contributions to psychophysiology: William G. Iacono. | Miller GA | β | 2010 | β |
| Genetic and environmental risk factors for adolescent-onset substance use disorders. | Meyers JL et al. | β | 2010 | β |
| The end of behavioral genetics? 2008. | McGue M | β | 2010 | β |
| Environmental adversity and increasing genetic risk for externalizing disorders. | Hicks BM et al. | β | 2009 | β |
| Externalizing disorders: cluster 5 of the proposed meta-structure for DSM-V and ICD-11. | Krueger RF et al. | β | 2009 | β |
| How Intelligence and Education Contribute to Substance Use: Hints from the Minnesota Twin Family Study. | Johnson W et al. | β | 2009 | β |
| The enrichment study of the Minnesota twin family study: increasing the yield of twin families at high risk for externalizing psychopathology. | Keyes MA et al. | β | 2009 | β |
| A developmental perspective on alcohol and youths 16 to 20 years of age. | Brown SA et al. | β | 2008 | β |
| Behavioral disinhibition and the development of early-onset addiction: common and specific influences. | Iacono WG et al. | β | 2008 | β |
| Predicting HIV/STD risk level and substance use disorders among incarcerated adolescents. | Rowe CL et al. | β | 2008 | β |
| The adolescent origins of substance use disorders. | McGue M et al. | β | 2008 | β |
| The developmental antecedents of illicit drug use: evidence from a 25-year longitudinal study. | Fergusson DM et al. | β | 2008 | β |
| The End of Behavioral Genetics? | McGue M | β | 2008 | β |