Genomewide association for schizophrenia in the CATIE study: results of stage 1.
paper
Cited
Public
Unavailable
- Authors
- Sullivan, P F; Lin, D; Tzeng, J-Y; van den Oord, E; Perkins, D; Stroup, T S; Wagner, M; Lee, S; Wright, F A; Zou, F; Liu, W; Downing, A M; Lieberman, J; Close, S L
- Year
- 2008
- Journal
- Molecular psychiatry
- PMID
- 18347602
- DOI
- 10.1038/mp.2008.25
- PMCID
- PMC3910086
Little is known for certain about the genetics of schizophrenia. The advent of genomewide association has been widely anticipated as a promising means to identify reproducible DNA sequence variation associated with this important and debilitating disorder. A total of 738 cases with DSM-IV schizophrenia (all participants in the CATIE study) and 733 group-matched controls were genotyped for 492,900 single-nucleotide polymorphisms (SNPs) using the Affymetrix 500K two-chip genotyping platform plus a custom 164K fill-in chip. Following multiple quality control steps for both subjects and SNPs, logistic regression analyses were used to assess the evidence for association of all SNPs with schizophrenia. We identified a number of promising SNPs for follow-up studies, although no SNP or multimarker combination of SNPs achieved genomewide statistical significance. Although a few signals coincided with genomic regions previously implicated in schizophrenia, chance could not be excluded. These data do not provide evidence for the involvement of any genomic region with schizophrenia detectable with moderate sample size. However, a planned genomewide association study for response phenotypes and inclusion of individual phenotype and genotype data from this study in meta-analyses hold promise for eventual identification of susceptibility and protective variants.
No figures extracted from this document.
No chunks — full text not yet ingested.
No entities extracted from this document yet.
No uploaded files.
Not in any collection.
No citations found.
In this knowledge base
External
| Title | Authors | Journal | Year | Link |
|---|---|---|---|---|
| SNP-based prediction of schizophrenia using machine learning. | Ramazanova Z et al. | — | 2026 | → |
| A review of post-GWAS studies in schizophrenia. | Maserrat S et al. | — | 2025 | → |
| Behavioural, psychiatric, and cognitive phenotypes associated with numbers of repeats of the FRAXE allele on the FMR2 gene | Golding J et al. | — | 2025 | — |
| Classification of schizophrenia, bipolar disorder and major depressive disorder with comorbid traits and deep learning algorithms. | Chen X et al. | — | 2025 | → |
| Plasma profiles of neurology-related proteins in at-risk mental state and first-episode psychosis: Associations with psychotic symptoms and cognitive performance. | Llaurador-Coll M et al. | — | 2025 | → |
| Behavioural, psychiatric, and cognitive phenotypes associated with numbers of repeats of the FRAXE allele on the FMR2 gene. | Golding J et al. | — | 2024 | → |
| Novel pathways linked to the expression of temperament in Merino sheep: a genome-wide association study. | Ding L et al. | — | 2024 | → |
| Analysis of structural variation among inbred mouse strains. | Arslan A et al. | — | 2023 | → |
| Genome-wide association study identified six loci associated with adverse drug reactions to aripiprazole in schizophrenia patients. | Wang X et al. | — | 2023 | → |
| Machine Learning and Pharmacogenomics at the Time of Precision Psychiatry. | Del Casale A et al. | — | 2023 | → |
| Uncovering a neurological protein signature for severe COVID-19. | El-Agnaf O et al. | — | 2023 | → |
| Genome-Wide Causation Studies of Complex Diseases. | Jiao R et al. | — | 2022 | → |
| Imputed expression of schizophrenia-associated genes and cognitive measures in patients with schizophrenia. | Fabbri C et al. | — | 2022 | → |
| Artificial image objects for classification of schizophrenia with GWAS-selected SNVs and convolutional neural network. | Chen X et al. | — | 2021 | → |
| Genome wide study of tardive dyskinesia in schizophrenia. | Lim K et al. | — | 2021 | → |
| Approaches to studying the genomic architecture of complex birth defects. | Taiwo TE et al. | — | 2020 | → |
| Association between a <i>TCF4</i> Polymorphism and Susceptibility to Schizophrenia. | Gao JY et al. | — | 2020 | → |
| Integration of Imaging (epi)Genomics Data for the Study of Schizophrenia Using Group Sparse Joint Nonnegative Matrix Factorization. | Wang M et al. | — | 2020 | → |
| Polygenic Risk Scores for Subtyping of Schizophrenia. | Chen J et al. | — | 2020 | → |
| Robust kernel association testing (RobKAT). | Martinez K et al. | — | 2020 | → |
| The impact on estimations of genetic correlations by the use of super-normal, unscreened, and family-history screened controls in genome wide case-control studies. | Kendler KS et al. | — | 2020 | → |
| Variants of GRM7 as risk factor and response to antipsychotic therapy in schizophrenia. | Liang W et al. | — | 2020 | → |
| DNA methylation correlates of PTSD: Recent findings and technical challenges. | Morrison FG et al. | — | 2019 | → |
| GWAS of Behavioral Traits. | Mehta D et al. | — | 2019 | → |
| Translational bioinformatics in mental health: open access data sources and computational biomarker discovery. | Tenenbaum JD et al. | — | 2019 | → |
| Unravelling the genetic basis of schizophrenia and bipolar disorder with GWAS: A systematic review. | Prata DP et al. | — | 2019 | → |
| A Powerful Test for SNP Effects on Multivariate Binary Outcomes using Kernel Machine Regression. | Davenport CA et al. | — | 2018 | → |
| Inference on phenotype-specific effects of genes using multivariate kernel machine regression. | Maity A et al. | — | 2018 | → |
| Longitudinal analyses of the DNA methylome in deployed military servicemen identify susceptibility loci for post-traumatic stress disorder. | Rutten BPF et al. | — | 2018 | → |
| Prediction of Schizophrenia Diagnosis by Integration of Genetically Correlated Conditions and Traits. | Chen J et al. | — | 2018 | → |
| The role of cadherin genes in five major psychiatric disorders: A literature update. | Hawi Z et al. | — | 2018 | → |
| A high-coverage Neandertal genome from Vindija Cave in Croatia. | Prüfer K et al. | — | 2017 | → |
| A method for integrating neuroimaging into genetic models of learning performance. | Mehta CM et al. | — | 2017 | → |
| BDNF rescues prefrontal dysfunction elicited by pyramidal neuron-specific DTNBP1 deletion in vivo. | Zhang W et al. | — | 2017 | → |
| Genetic loci associated with an earlier age at onset in multiplex schizophrenia. | Woolston AL et al. | — | 2017 | → |
| Genetics of schizophrenia: A consensus paper of the WFSBP Task Force on Genetics. | Giegling I et al. | — | 2017 | → |
| Role of 108 schizophrenia-associated loci in modulating psychopathological dimensions in schizophrenia and bipolar disorder. | Fabbri C et al. | — | 2017 | → |
| Schizophrenia genetics in the genome-wide era: a review of Japanese studies. | Kanazawa T et al. | — | 2017 | → |
| The GRM7 gene, early response to risperidone, and schizophrenia: a genome-wide association study and a confirmatory pharmacogenetic analysis. | Sacchetti E et al. | — | 2017 | → |
| Unraveling the genetic architecture of copy number variants associated with schizophrenia and other neuropsychiatric disorders. | Rutkowski TP et al. | — | 2017 | → |
| Consensus paper of the WFSBP Task Force on Biological Markers: Criteria for biomarkers and endophenotypes of schizophrenia part II: Cognition, neuroimaging and genetics. | Schmitt A et al. | — | 2016 | → |
| Epigenetic profiling of human brain differential DNA methylation networks in schizophrenia. | Lee SA et al. | — | 2016 | → |
| From Linkage Studies to Epigenetics: What We Know and What We Need to Know in the Neurobiology of Schizophrenia. | Cariaga-Martinez A et al. | — | 2016 | → |
| Genetics of Schizophrenia: Historical Insights and Prevailing Evidence. | van de Leemput J et al. | — | 2016 | → |
| Genome-wide Association Study of Autism Spectrum Disorder in the East Asian Populations. | Liu X et al. | — | 2016 | → |
| LINE1 insertions as a genomic risk factor for schizophrenia: Preliminary evidence from an affected family. | Guffanti G et al. | — | 2016 | → |
| Precision medicine for psychopharmacology: a general introduction. | Shin C et al. | — | 2016 | → |
| Systems Nutrigenomics Reveals Brain Gene Networks Linking Metabolic and Brain Disorders. | Meng Q et al. | — | 2016 | → |
| The identification of novel genetic variants associated with antipsychotic treatment response outcomes in first-episode schizophrenia patients. | Drögemöller BI et al. | — | 2016 | → |
| Two-stage additional evidence support association of common variants in the HDAC3 with the increasing risk of schizophrenia susceptibility. | Jia X et al. | — | 2016 | → |
| Angiogenesis in the pathophysiology of schizophrenia - a comprehensive review and a conceptual hypothesis. | Lopes R et al. | — | 2015 | → |
| Candidate gene-environment interaction research: reflections and recommendations. | Dick DM et al. | — | 2015 | → |
| DNA-methyltransferase1 (DNMT1) binding to CpG rich GABAergic and BDNF promoters is increased in the brain of schizophrenia and bipolar disorder patients. | Dong E et al. | — | 2015 | → |
| Effect of polymorphisms of three genes mediating monoamine signalling on brain morphometry in schizophrenia and healthy subjects. | Vijayakumari AA et al. | — | 2015 | → |
| Genetic association of ACSM1 variation with schizophrenia and major depressive disorder in the Han Chinese population. | Li W et al. | — | 2015 | → |
| Gsx1 expression defines neurons required for prepulse inhibition. | Bergeron SA et al. | — | 2015 | → |
| Identification and functional studies of regulatory variants responsible for the association of <i>NRG3</i> with a delusion phenotype in schizophrenia. | Zeledón M et al. | — | 2015 | → |
| Meta-analysis of data from the Psychiatric Genomics Consortium and additional samples supports association of CACNA1C with risk for schizophrenia. | Takahashi S et al. | — | 2015 | → |
| New discoveries in schizophrenia genetics reveal neurobiological pathways: A review of recent findings. | Kotlar AV et al. | — | 2015 | → |
| Schizophrenia or schizophrenias? The challenge of genetic parsing of a complex disorder. | Jablensky A | — | 2015 | → |
| Uncovering the hidden risk architecture of the schizophrenias: confirmation in three independent genome-wide association studies. | Arnedo J et al. | — | 2015 | → |
| Aetiology of schizophrenia and implications for nursing practice: a literature review. | Cunningham C et al. | — | 2014 | → |
| A sequence variant in human KALRN impairs protein function and coincides with reduced cortical thickness. | Russell TA et al. | — | 2014 | → |
| Association study identifying a new susceptibility gene (AUTS2) for schizophrenia. | Zhang B et al. | — | 2014 | → |
| Comparison of the heritability of schizophrenia and endophenotypes in the COGS-1 family study. | Light G et al. | — | 2014 | → |
| Differential effects of common variants in SCN2A on general cognitive ability, brain physiology, and messenger RNA expression in schizophrenia cases and control individuals. | Dickinson D et al. | — | 2014 | → |
| Gene × environment interaction studies have not properly controlled for potential confounders: the problem and the (simple) solution. | Keller MC | — | 2014 | → |
| Identification of candidate single-nucleotide polymorphisms in NRXN1 related to antipsychotic treatment response in patients with schizophrenia. | Jenkins A et al. | — | 2014 | → |
| Network.assisted analysis to prioritize GWAS results: principles, methods and perspectives. | Jia P et al. | — | 2014 | → |
| Neuregulin-ERBB signaling in the nervous system and neuropsychiatric diseases. | Mei L et al. | — | 2014 | → |
| Pharmacogenetics of second-generation antipsychotics. | Brennan MD | — | 2014 | → |
| Reciprocal duplication of the Williams-Beuren syndrome deletion on chromosome 7q11.23 is associated with schizophrenia. | Mulle JG et al. | — | 2014 | → |
| Replication of SULT4A1-1 as a pharmacogenetic marker of olanzapine response and evidence of lower weight gain in the high response group. | Ramsey TL et al. | — | 2014 | → |
| [Replicative association analysis of genetic markers of cognitive traits with Alzheimer's disease in a Russian population]. | Stepanov VA et al. | — | 2014 | → |
| A population-based association study of 2q32.3 and 8q21.3 loci with schizophrenia in Han Chinese. | Guan F et al. | — | 2013 | → |
| Association study of 167 candidate genes for schizophrenia selected by a multi-domain evidence-based prioritization algorithm and neurodevelopmental hypothesis. | Zhao Z et al. | — | 2013 | → |
| Beyond single-marker analyses: mining whole genome scans for insights into treatment responses in severe sepsis. | Man M et al. | — | 2013 | → |
| Deep resequencing and association analysis of schizophrenia candidate genes. | Crowley JJ et al. | — | 2013 | → |
| DISC1 in adult ADHD patients: an association study in two European samples. | Jacobsen KK et al. | — | 2013 | → |
| Discovery, validation and characterization of Erbb4 and Nrg1 haplotypes using data from three genome-wide association studies of schizophrenia. | Agim ZS et al. | — | 2013 | → |
| Dopaminergic gene polymorphisms and cognitive function in a north Indian schizophrenia cohort. | Kukshal P et al. | — | 2013 | → |
| Evidence for shared genetic risk between methamphetamine-induced psychosis and schizophrenia. | Ikeda M et al. | — | 2013 | → |
| Genetic predictors of risk and resilience in psychiatric disorders: a cross-disorder genome-wide association study of functional impairment in major depressive disorder, bipolar disorder, and schizophrenia. | McGrath LM et al. | — | 2013 | → |
| Genetics of psychiatric disorders in the GWAS era: an update on schizophrenia. | Schwab SG et al. | — | 2013 | → |
| Genome-wide association study of patient-rated and clinician-rated global impression of severity during antipsychotic treatment. | Clark SL et al. | — | 2013 | → |
| Genome-wide association study of schizophrenia using microsatellite markers in the Japanese population. | Shibata H et al. | — | 2013 | → |
| Genome-wide supported variant MIR137 and severe negative symptoms predict membership of an impaired cognitive subtype of schizophrenia. | Green MJ et al. | — | 2013 | → |
| Genotype-based ancestral background consistently predicts efficacy and side effects across treatments in CATIE and STAR*D. | Adkins DE et al. | — | 2013 | → |
| Genotypic variation in the SV2C gene impacts response to atypical antipsychotics the CATIE study. | Ramsey TL et al. | — | 2013 | → |
| Haploinsufficiency of KDM6A is associated with severe psychomotor retardation, global growth restriction, seizures and cleft palate. | Lindgren AM et al. | — | 2013 | → |
| Influence of ANKK1 and DRD2 polymorphisms in response to haloperidol. | Giegling I et al. | — | 2013 | → |
| KCNIP4 as a candidate gene for personality disorders and adult ADHD. | Weißflog L et al. | — | 2013 | → |
| Neuroimaging as a potential biomarker to optimize psychiatric research and treatment. | Walton E et al. | — | 2013 | → |
| Pharmacogenetics of antidepressants, mood stabilizers, and antipsychotics in diverse human populations. | Murphy E et al. | — | 2013 | → |
| Questions about DISC1 as a genetic risk factor for schizophrenia. | Sullivan PF | — | 2013 | → |
| Regulation of spine formation by ErbB4 in PV-positive interneurons. | Yin DM et al. | — | 2013 | → |
| Taiwan Schizophrenia Linkage Study: lessons learned from endophenotype-based genome-wide linkage scans and perspective. | Chen WJ | — | 2013 | → |
| The emerging spectrum of allelic variation in schizophrenia: current evidence and strategies for the identification and functional characterization of common and rare variants. | Mowry BJ et al. | — | 2013 | → |
| Variants in the 15q25 gene cluster are associated with risk for schizophrenia and bipolar disorder. | Jackson KJ et al. | — | 2013 | → |
| A gene expression and systems pathway analysis of the effects of clozapine compared to haloperidol in the mouse brain implicates susceptibility genes for schizophrenia. | Rizig MA et al. | — | 2012 | → |
| An environmental analysis of genes associated with schizophrenia: hypoxia and vascular factors as interacting elements in the neurodevelopmental model. | Schmidt-Kastner R et al. | — | 2012 | → |
| Association of the ZFPM2 gene with antipsychotic-induced parkinsonism in schizophrenia patients. | Greenbaum L et al. | — | 2012 | → |
| Clinical applications of schizophrenia genetics: genetic diagnosis, risk, and counseling in the molecular era. | Costain G et al. | — | 2012 | → |
| DISC1-binding proteins in neural development, signalling and schizophrenia. | Bradshaw NJ et al. | — | 2012 | → |
| Diverse types of genetic variation converge on functional gene networks involved in schizophrenia. | Gilman SR et al. | — | 2012 | → |
| DOCK4 and CEACAM21 as novel schizophrenia candidate genes in the Jewish population. | Alkelai A et al. | — | 2012 | → |
| Follow-up association study of linkage regions reveals multiple candidate genes for carotid plaque in Dominicans. | Dong C et al. | — | 2012 | → |
| Gender-specific association of TSNAX/DISC1 locus for schizophrenia and bipolar affective disorder in South Indian population. | Ram Murthy A et al. | — | 2012 | → |
| Genetics of schizophrenia from a clinicial perspective. | Kukshal P et al. | — | 2012 | → |
| Genome wide association studies (GWAS) and copy number variation (CNV) studies of the major psychoses: what have we learnt? | Lee KW et al. | — | 2012 | → |
| Genome-wide association studies in schizophrenia, and potential etiological and functional implications of their results. | Hosák L et al. | — | 2012 | → |
| Genome-wide association studies of schizophrenia: does bigger lead to better results? | Bergen SE et al. | — | 2012 | → |
| Genome-wide association study of antipsychotic-induced QTc interval prolongation. | Aberg K et al. | — | 2012 | → |
| Genome-wide linkage scan of antisocial behavior, depression, and impulsive substance use in the UCSF family alcoholism study. | Gizer IR et al. | — | 2012 | → |
| Human genetics of schizophrenia. | Claes S et al. | — | 2012 | → |
| Hypothesis-driven candidate genes for schizophrenia compared to genome-wide association results. | Collins AL et al. | — | 2012 | → |
| Immune system gene dysregulation in autism and schizophrenia. | Michel M et al. | — | 2012 | → |
| Investigating association of four gene regions (GABRB3, MAOB, PAH, and SLC6A4) with five symptoms in schizophrenia. | Sun J et al. | — | 2012 | → |
| Investigation of allelic heterogeneity of the CCK-A receptor gene in paranoid schizophrenia. | Zheng C et al. | — | 2012 | → |
| Involvement of PTPN5, the gene encoding the striatal-enriched protein tyrosine phosphatase, in schizophrenia and cognition. | Pelov I et al. | — | 2012 | → |
| Methylome-wide comparison of human genomic DNA extracted from whole blood and from EBV-transformed lymphocyte cell lines. | Åberg K et al. | — | 2012 | → |
| Modelling the contribution of family history and variation in single nucleotide polymorphisms to risk of schizophrenia: a Danish national birth cohort-based study. | Agerbo E et al. | — | 2012 | → |
| Multivariate phenotype association analysis by marker-set kernel machine regression. | Maity A et al. | — | 2012 | → |
| No association of a set of candidate genes on haloperidol side effects. | Drago A et al. | — | 2012 | → |
| Pathway based analysis of genotypes in relation to alcohol dependence. | Reimers MA et al. | — | 2012 | → |
| Resequencing and association analysis of the KALRN and EPHB1 genes and their contribution to schizophrenia susceptibility. | Kushima I et al. | — | 2012 | → |
| Schizophrenia genes: on the matter of their convergence. | Rujescu D | — | 2012 | → |
| Schizophrenia genetics: progress, at last. | Mulle JG | — | 2012 | → |
| Schizophrenia genetics: putting all the pieces together. | Girard SL et al. | — | 2012 | → |
| Searching joint association signals in CATIE schizophrenia genome-wide association studies through a refined integrative network approach. | Jia P et al. | — | 2012 | → |
| SNP-based analysis of neuroactive ligand-receptor interaction pathways implicates PGE2 as a novel mediator of antipsychotic treatment response: data from the CATIE study. | Adkins DE et al. | — | 2012 | → |
| Statistical epistasis and progressive brain change in schizophrenia: an approach for examining the relationships between multiple genes. | Andreasen NC et al. | — | 2012 | → |
| Sulfotransferase 4A1 Haplotype 1 (SULT4A1-1) Is Associated With Decreased Hospitalization Events in Antipsychotic-Treated Patients With Schizophrenia. | Liu Q et al. | — | 2012 | → |
| Support for association of HSPG2 with tardive dyskinesia in Caucasian populations. | Greenbaum L et al. | — | 2012 | → |
| Targeted pharmacogenetic analysis of antipsychotic response in the CATIE study. | Liu Q et al. | — | 2012 | → |
| The genetic architecture of schizophrenia: new mutations and emerging paradigms. | Rodriguez-Murillo L et al. | — | 2012 | → |
| Translocations disrupting PHF21A in the Potocki-Shaffer-syndrome region are associated with intellectual disability and craniofacial anomalies. | Kim HG et al. | — | 2012 | → |
| A critical review of the first 10 years of candidate gene-by-environment interaction research in psychiatry. | Duncan LE et al. | — | 2011 | → |
| A genome-wide linkage scan for distinct subsets of schizophrenia characterized by age at onset and neurocognitive deficits. | Lien YJ et al. | — | 2011 | → |
| Application of systems biology approach identifies and validates GRB2 as a risk gene for schizophrenia in the Irish Case Control Study of Schizophrenia (ICCSS) sample. | Sun J et al. | — | 2011 | → |
| Assessment of 2q23.1 microdeletion syndrome implicates MBD5 as a single causal locus of intellectual disability, epilepsy, and autism spectrum disorder. | Talkowski ME et al. | — | 2011 | → |
| Comparative linkage meta-analysis reveals regionally-distinct, disparate genetic architectures: application to bipolar disorder and schizophrenia. | Tang B et al. | — | 2011 | → |
| Comprehensive gene-based association study of a chromosome 20 linked region implicates novel risk loci for depressive symptoms in psychotic illness. | Bigdeli TB et al. | — | 2011 | → |
| Control of population stratification by correlation-selected principal components. | Lee S et al. | — | 2011 | → |
| Cytochrome P450 testing for prescribing antipsychotics in adults with schizophrenia: systematic review and meta-analyses. | Fleeman N et al. | — | 2011 | → |
| Epigenetic GABAergic targets in schizophrenia and bipolar disorder. | Guidotti A et al. | — | 2011 | → |
| Evaluation of risk loci for schizophrenia derived from genome-wide association studies in a German population. | Schanze D et al. | — | 2011 | → |
| Evidence for a SULT4A1 haplotype correlating with baseline psychopathology and atypical antipsychotic response. | Ramsey TL et al. | — | 2011 | → |
| Evidence of sex-modulated association of ZNF804A with schizophrenia. | Zhang F et al. | — | 2011 | → |
| Fine mapping of ZNF804A and genome-wide significant evidence for its involvement in schizophrenia and bipolar disorder. | Williams HJ et al. | — | 2011 | → |
| Genetics of schizophrenia: new findings and challenges. | Gejman PV et al. | — | 2011 | → |
| Genetic variation in CYP3A43 explains racial difference in olanzapine clearance. | Bigos KL et al. | — | 2011 | → |
| Genome-wide association study in German patients with attention deficit/hyperactivity disorder. | Hinney A et al. | — | 2011 | → |
| Genome-wide pharmacogenomic analysis of response to treatment with antipsychotics. | McClay JL et al. | — | 2011 | → |
| Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs. | Adkins DE et al. | — | 2011 | → |
| Genome-wide pharmacogenomic study of neurocognition as an indicator of antipsychotic treatment response in schizophrenia. | McClay JL et al. | — | 2011 | → |
| GWA study data mining and independent replication identify cardiomyopathy-associated 5 (CMYA5) as a risk gene for schizophrenia. | Chen X et al. | — | 2011 | → |
| Identification of blood biomarkers for psychosis using convergent functional genomics. | Kurian SM et al. | — | 2011 | → |
| Identification of new schizophrenia susceptibility loci in an ethnically homogeneous, family-based, Arab-Israeli sample. | Alkelai A et al. | — | 2011 | → |
| Increased de novo copy number variants in the offspring of older males. | Flatscher-Bader T et al. | — | 2011 | → |
| Integrated genetic and genomic approach in the SingaporeTranslational and Clinical Research in Psychosis Study: an overview. | Sim K et al. | — | 2011 | → |
| Methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms and age of onset in schizophrenia: a combined analysis of independent samples. | Saetre P et al. | — | 2011 | → |
| Modifiers and subtype-specific analyses in whole-genome association studies: a likelihood framework. | Lee PH et al. | — | 2011 | → |
| Network-assisted Causal Gene Detection in Genome-wide Association Studies: An Improved Module Search Algorithm. | Jia P et al. | — | 2011 | → |
| Pathway-based analysis of GWAS datasets: effective but caution required. | Jia P et al. | — | 2011 | → |
| Schizophrenia genetics: where next? | Kim Y et al. | — | 2011 | → |
| [Systematic review of the Genomewide Association Studies (GWAS) in schizophrenia]. | Valiente A et al. | — | 2011 | → |
| Two non-synonymous markers in PTPN21, identified by genome-wide association study data-mining and replication, are associated with schizophrenia. | Chen J et al. | — | 2011 | → |
| Where are the missing pieces of the schizophrenia genetics puzzle? | Girard SL et al. | — | 2011 | → |
| ZNF804A risk allele is associated with relatively intact gray matter volume in patients with schizophrenia. | Donohoe G et al. | — | 2011 | → |
| A candidate gene study of Tardive dyskinesia in the CATIE schizophrenia trial. | Tsai HT et al. | — | 2010 | → |
| A genome-wide quantitative trait loci scan of neurocognitive performances in families with schizophrenia. | Lien YJ et al. | — | 2010 | → |
| A novel microRNA and transcription factor mediated regulatory network in schizophrenia. | Guo AY et al. | — | 2010 | → |
| Association study of NRG1, DTNBP1, RGS4, G72/G30, and PIP5K2A with schizophrenia and symptom severity in a Hungarian sample. | Réthelyi JM et al. | — | 2010 | → |
| Common promoter variants of the NDUFV2 gene do not confer susceptibility to schizophrenia in Han Chinese. | Zhang W et al. | — | 2010 | → |
| Common variants conferring risk of schizophrenia: a pathway analysis of GWAS data. | Jia P et al. | — | 2010 | → |
| Cross-disorder genomewide analysis of schizophrenia, bipolar disorder, and depression. | Huang J et al. | — | 2010 | → |
| Cytokine hypothesis of schizophrenia pathogenesis: evidence from human studies and animal models. | Watanabe Y et al. | — | 2010 | → |
| Epistatic and functional interactions of catechol-o-methyltransferase (COMT) and AKT1 on neuregulin1-ErbB signaling in cell models. | Sei Y et al. | — | 2010 | → |
| Evidence for association of the GLI2 gene with tardive dyskinesia in patients with chronic schizophrenia. | Greenbaum L et al. | — | 2010 | → |
| Failure to find an association between myosin heavy chain 9, non-muscle (MYH9) and schizophrenia: a three-stage case-control association study. | Amagane H et al. | — | 2010 | → |
| Fine mapping of AHI1 as a schizophrenia susceptibility gene: from association to evolutionary evidence. | Torri F et al. | — | 2010 | → |
| Fine-mapping reveals novel alternative splicing of the dopamine transporter. | Talkowski ME et al. | — | 2010 | → |
| Fitting the pieces together: current research on the genetic basis of attention-deficit/hyperactivity disorder (ADHD). | Stergiakouli E et al. | — | 2010 | → |
| Functional variants of TSPAN8 are associated with bipolar disorder and schizophrenia. | Scholz CJ et al. | — | 2010 | → |
| Genetic repositories for the study of major psychiatric conditions: what do we know about ethnic minorities' genetic vulnerability? | Oquendo MA et al. | — | 2010 | → |
| Genetics and intermediate phenotypes of the schizophrenia--bipolar disorder boundary. | Ivleva EI et al. | — | 2010 | → |
| Genetics in schizophrenia: where are we and what next? | Tiwari AK et al. | — | 2010 | → |
| Gene variants associated with schizophrenia in a Norwegian genome-wide study are replicated in a large European cohort. | Athanasiu L et al. | — | 2010 | → |
| Genome-wide approaches to schizophrenia. | Duan J et al. | — | 2010 | → |
| Genome-wide association scan for five major dimensions of personality. | Terracciano A et al. | — | 2010 | → |
| Genome-wide association studies: a powerful tool for neurogenomics. | Cowperthwaite MC et al. | — | 2010 | → |
| Genomewide association study of movement-related adverse antipsychotic effects. | Aberg K et al. | — | 2010 | → |
| Genome-wide association study of recurrent major depressive disorder in two European case-control cohorts. | Muglia P et al. | — | 2010 | → |
| Genome-wide linkage using the Social Responsiveness Scale in Utah autism pedigrees. | Coon H et al. | — | 2010 | → |
| Haplotype-based pharmacogenetic analysis for longitudinal quantitative traits in the presence of dropout. | Tzeng JY et al. | — | 2010 | → |
| Human behavioral informatics in genetic studies of neuropsychiatric disease: multivariate profile-based analysis. | Bloss CS et al. | — | 2010 | → |
| Impact of the AHI1 gene on the vulnerability to schizophrenia: a case-control association study. | Rivero O et al. | — | 2010 | → |
| Lymphoblast and brain expression of AHI1 and the novel primate-specific gene, C6orf217, in schizophrenia and bipolar disorder. | Slonimsky A et al. | — | 2010 | → |
| Methods: genetic epidemiology. | Benke KS et al. | — | 2010 | → |
| MicroRNA dysregulation in psychiatric disease. | Miller BH et al. | — | 2010 | → |
| Molecular genetics of attention-deficit/hyperactivity disorder: an overview. | Banaschewski T et al. | — | 2010 | → |
| Narrowing the boundaries of the genetic architecture of schizophrenia. | Wray NR et al. | — | 2010 | → |
| Nature and nurture in neuropsychiatric genetics: where do we stand? | Dick DM et al. | — | 2010 | → |
| New findings in the genetics of major psychoses. | Nöthen MM et al. | — | 2010 | → |
| New Genetic Findings in Schizophrenia: Is there Still Room for the Dopamine Hypothesis of Schizophrenia? | Nieratschker V et al. | — | 2010 | → |
| No association of the serotonin transporter polymorphisms 5-HTTLPR and RS25531 with schizophrenia or neurocognition. | Konneker TI et al. | — | 2010 | → |
| Replication of association between schizophrenia and ZNF804A in the Irish Case-Control Study of Schizophrenia sample. | Riley B et al. | — | 2010 | → |
| REVIEW: Genome-wide findings in schizophrenia and the role of gene-environment interplay. | Van Winkel R et al. | — | 2010 | → |
| Schizophrenia gene networks and pathways and their applications for novel candidate gene selection. | Sun J et al. | — | 2010 | → |
| Suggestive linkage of the child behavior checklist juvenile bipolar disorder phenotype to 1p21, 6p21, and 8q21. | Doyle AE et al. | — | 2010 | → |
| SZGR: a comprehensive schizophrenia gene resource. | Jia P et al. | — | 2010 | → |
| The cross-sectional GRAS sample: a comprehensive phenotypical data collection of schizophrenic patients. | Ribbe K et al. | — | 2010 | → |
| The multidimensionality of schizotypy in nonpsychotic relatives of patients with schizophrenia and its applications in ordered subsets linkage analysis of schizophrenia. | Lien YJ et al. | — | 2010 | → |
| The psychosis susceptibility gene ZNF804A: associations, functions, and phenotypes. | Donohoe G et al. | — | 2010 | → |
| The role of genetics in the etiology of schizophrenia. | Gejman PV et al. | — | 2010 | → |
| What have the genomics ever done for the psychoses? | Gill M et al. | — | 2010 | → |
| Accuracy of genome-wide imputation of untyped markers and impacts on statistical power for association studies. | Hao K et al. | — | 2009 | → |
| A genome-wide association study of schizophrenia using brain activation as a quantitative phenotype. | Potkin SG et al. | — | 2009 | → |
| A genome-wide investigation of SNPs and CNVs in schizophrenia. | Need AC et al. | — | 2009 | → |
| A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB. | Need AC et al. | — | 2009 | → |
| Alternatively Spliced Genes as Biomarkers for Schizophrenia, Bipolar Disorder and Psychosis: A Blood-Based Spliceome-Profiling Exploratory Study. | Glatt SJ et al. | — | 2009 | → |
| A multi-dimensional evidence-based candidate gene prioritization approach for complex diseases-schizophrenia as a case. | Sun J et al. | — | 2009 | → |
| A primate-specific, brain isoform of KCNH2 affects cortical physiology, cognition, neuronal repolarization and risk of schizophrenia. | Huffaker SJ et al. | — | 2009 | → |
| Association study of 21 circadian genes with bipolar I disorder, schizoaffective disorder, and schizophrenia. | Mansour HA et al. | — | 2009 | → |
| A systematic method for estimating individual responses to treatment with antipsychotics in CATIE. | van den Oord EJ et al. | — | 2009 | → |
| Characterization of the action of antipsychotic subtypes on valproate-induced chromatin remodeling. | Guidotti A et al. | — | 2009 | → |
| Chromosome 13q13-q14 locus overlaps mood and psychotic disorders: the relevance for redefining phenotype. | Maziade M et al. | — | 2009 | → |
| Does the presenilin 2 gene predispose to schizophrenia? | Zhang J et al. | — | 2009 | → |
| Evidence for the association of the DAOA (G72) gene with schizophrenia and bipolar disorder but not for the association of the DAO gene with schizophrenia. | Bass NJ et al. | — | 2009 | → |
| From bench to bedside: translating new research from genetics and neuroimaging into treatment development for early-onset schizophrenia. | Kumra S et al. | — | 2009 | → |
| Future classification of psychotic disorders. | Gaebel W et al. | — | 2009 | → |
| GABAergic promoter hypermethylation as a model to study the neurochemistry of schizophrenia vulnerability. | Costa E et al. | — | 2009 | → |
| Gene discovery through imaging genetics: identification of two novel genes associated with schizophrenia. | Potkin SG et al. | — | 2009 | → |
| Genetic association and post-mortem brain mRNA analysis of DISC1 and related genes in schizophrenia. | Rastogi A et al. | — | 2009 | → |
| Genetics of psychosis; insights from views across the genome. | O'Donovan MC et al. | — | 2009 | → |
| [Genetics of weight gain associated with antipsychotic medications]. | Müller DJ et al. | — | 2009 | → |
| Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo. | Sullivan PF et al. | — | 2009 | → |
| Genomewide association studies: history, rationale, and prospects for psychiatric disorders. | Psychiatric GWAS Consortium Coordinating Committee et al. | — | 2009 | → |
| Genome-wide association studies in ADHD. | Franke B et al. | — | 2009 | → |
| Genome-wide association study of alcohol dependence. | Treutlein J et al. | — | 2009 | → |
| Genome-wide association study of antipsychotic-induced parkinsonism severity among schizophrenia patients. | Alkelai A et al. | — | 2009 | → |
| Involvement of SMARCA2/BRM in the SWI/SNF chromatin-remodeling complex in schizophrenia. | Koga M et al. | — | 2009 | → |
| Linkage and association studies of anxiety disorders. | Hamilton SP | — | 2009 | → |
| Meta-analysis of genome-wide association studies with overlapping subjects. | Lin DY et al. | — | 2009 | → |
| New findings from genetic association studies of schizophrenia. | Williams HJ et al. | — | 2009 | → |
| Persistence criteria for susceptibility genes for schizophrenia: a discussion from an evolutionary viewpoint. | Doi N et al. | — | 2009 | → |
| Rare structural variants in schizophrenia: one disorder, multiple mutations; one mutation, multiple disorders. | Sebat J et al. | — | 2009 | → |
| Schizophrenia: from the brain to peripheral markers. A consensus paper of the WFSBP task force on biological markers. | Stober G et al. | — | 2009 | → |
| Schizophrenia genetics: advancing on two fronts. | Owen MJ et al. | — | 2009 | → |
| Schizophrenia genetics: new insights from new approaches. | Williams HJ et al. | — | 2009 | → |
| Searching genetic risk factors for schizophrenia and bipolar disorder: learn from the past and back to the future. | Alaerts M et al. | — | 2009 | → |
| The DISC locus and schizophrenia: evidence from an association study in a central European sample and from a meta-analysis across different European populations. | Schumacher J et al. | — | 2009 | → |
| The intersection of pharmacology, imaging, and genetics in the development of personalized medicine. | Gerretsen P et al. | — | 2009 | → |
| The role of DNA copy number variation in schizophrenia. | Tam GW et al. | — | 2009 | → |
| The trace amine associated receptor (TAAR6) gene is not associated with schizophrenia in the Irish Case-Control Study of Schizophrenia (ICCSS) sample. | Vladimirov VI et al. | — | 2009 | → |
| Three-cohort targeted gene screening reveals a non-synonymous TRKA polymorphism associated with schizophrenia. | van Schijndel JE et al. | — | 2009 | → |
| An interview with... Cliff Tabin. | Tabin C | — | 2008 | → |
| Functional polymorphisms in PRODH are associated with risk and protection for schizophrenia and fronto-striatal structure and function. | Kempf L et al. | — | 2008 | → |
| Genetic causality in schizophrenia and bipolar disorder: out with the old and in with the new. | Porteous D | — | 2008 | → |
| Genetic research in schizophrenia: new tools and future perspectives. | Bertram L | — | 2008 | → |
| Psychiatric genetics: progress amid controversy. | Burmeister M et al. | — | 2008 | → |
| Psychiatric genetics: The brains of the family. | Abbott A | — | 2008 | → |
| Schizophrenia genetics: the search for a hard lead. | Sullivan PF | — | 2008 | → |
| The dice are rolling for schizophrenia genetics. | Sullivan PF | — | 2008 | → |