Behavioral disinhibition and the development of substance-use disorders: findings from the Minnesota Twin Family Study.
paper
Cited
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- Authors
- Iacono, W G; Carlson, S R; Taylor, J; Elkins, I J; McGue, M
- Year
- 1999
- Journal
- Development and psychopathology
- PMID
- 10624730
- DOI
- 10.1017/s0954579499002369
One variant of substance-use disorder is characterized by behavioral disinhibition. In this report, we martial evidence for a model for the development of this variant. We hypothesize that genetic liability for this variant is reflected in a spectrum of risk indicators linked to the inability or unwillingness to inhibit behavioral impulses. Included in this spectrum are personality traits suggesting low constraint, and externalizing psychopathology, including conduct, oppositional defiant, and attention-deficit disorder in children and antisocial personality disorder and behavior in adults. We further hypothesize that these individual differences in behavioral disinhibition are manifestations of underlying central nervous system processes associated with various psychophysiological anomalies, some of which may index genetic risk for substance abuse. Support for the model is derived from the analysis of findings from the Minnesota Twin Family Study, an epidemiological investigation of approximately 2,700 adolescent twins and their parents.
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| The effect of general and drug-specific family environments on comorbid and drug-specific problem behavior: a longitudinal examination. | Epstein M et al. | β | 2013 | β |
| The Michigan State University Twin Registry (MSUTR): an update. | Burt SA et al. | β | 2013 | β |
| The moderating effect of family involvement on substance use risk factors in adolescents with severe emotional and behavioral challenges. | Schlauch RC et al. | β | 2013 | β |
| Adolescent substance use groups: antecedent and concurrent personality differences in a longitudinal study. | Oliva EM et al. | β | 2012 | β |
| An examination of environmental and genetic contributions to the determinants of suicidal behavior among male twins. | Smith AR et al. | β | 2012 | β |
| An examination of pathways from childhood maltreatment to adolescent binge drinking. | Shin SH et al. | β | 2012 | β |
| Are the symptoms of cannabis use disorder best accounted for by dimensional, categorical, or factor mixture models? A comparison of male and female young adults. | Gillespie NA et al. | β | 2012 | β |
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| Cognitive control links alcohol use, trait disinhibition, and reduced cognitive capacity: Evidence for medial prefrontal cortex dysregulation during reward-seeking behavior. | Bogg T et al. | β | 2012 | β |
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| Decline in genetic influence on the co-occurrence of alcohol, marijuana, and nicotine dependence symptoms from age 14 to 29. | Vrieze SI et al. | β | 2012 | β |
| Delineating physiologic defensive reactivity in the domain of self-report: phenotypic and etiologic structure of dispositional fear. | Kramer MD et al. | β | 2012 | β |
| Examination of the structure of psychopathology using latent class analysis. | Olino TM et al. | β | 2012 | β |
| Examining electrodermal hyporeactivity as a marker of externalizing psychopathology: a twin study. | Isen JD et al. | β | 2012 | β |
| Genetic and environmental contributions to the association between anthropometric measures and iq: a study of Minnesota twins at age 11 and 17. | Silventoinen K et al. | β | 2012 | β |
| Index of the transmissible common liability to addiction: heritability and prospective associations with substance abuse and related outcomes. | Hicks BM et al. | β | 2012 | β |
| Psychopathic personality traits and environmental contexts: Differential correlates, gender differences, and genetic mediation. | Hicks BM et al. | β | 2012 | β |
| Reconceptualizing antisocial deviance in neurobehavioral terms. | Patrick CJ et al. | β | 2012 | β |
| Relationship between personality change and the onset and course of alcohol dependence in young adulthood. | Hicks BM et al. | β | 2012 | β |
| The co-occurring use and misuse of cannabis and tobacco: a review. | Agrawal A et al. | β | 2012 | β |
| The Minnesota Center for Twin and Family Research genome-wide association study. | Miller MB et al. | β | 2012 | β |
| Youth appraisals of inter-parental conflict and genetic and environmental contributions to attention-deficit hyperactivity disorder: examination of GxE effects in a twin sample. | Nikolas M et al. | β | 2012 | β |
| Age-of-onset or behavioral sub-types? A prospective comparison of two approaches to characterizing the heterogeneity within antisocial behavior. | Burt SA et al. | β | 2011 | β |
| A Twin and Adoption Study of Reading Achievement: Exploration of Shared-Environmental and Gene-Environment-Interaction Effects. | Kirkpatrick RM et al. | β | 2011 | β |
| Contributions of parent-adolescent negative emotionality, adolescent conflict, and adoption status to adolescent externalizing behaviors. | Koh BD et al. | β | 2011 | β |
| Development and validation of the Minnesota borderline personality disorder scale. | Bornovalova MA et al. | β | 2011 | β |
| Dietary restraint moderates genetic risk for binge eating. | Racine SE et al. | β | 2011 | β |
| Explaining associations between cannabis use disorders in adolescence and later major depression: a test of the psychosocial failure model. | Marmorstein NR et al. | β | 2011 | β |
| Externalizing psychopathology and behavioral disinhibition: working memory mediates signal discriminability and reinforcement moderates response bias in approach-avoidance learning. | Endres MJ et al. | β | 2011 | β |
| Fluid intelligence and psychosocial outcome: from logical problem solving to social adaptation. | Huepe D et al. | β | 2011 | β |
| Genetic and environmental influences on impulsivity: a meta-analysis of twin, family and adoption studies. | Bezdjian S et al. | β | 2011 | β |
| Genetic and environmental influences on personality trait stability and growth during the transition to adulthood: a three-wave longitudinal study. | Hopwood CJ et al. | β | 2011 | β |
| Genome-wide association study of conduct disorder symptomatology. | Dick DM et al. | β | 2011 | β |
| Levels of risk: maternal-, middle childhood-, and neighborhood-level predictors of adolescent disinhibitory behaviors from a longitudinal birth cohort in the United States. | Keyes KM et al. | β | 2011 | β |
| New variable selection methods for zero-inflated count data with applications to the substance abuse field. | Buu A et al. | β | 2011 | β |
| Parental divorce and disordered eating: an investigation of a gene-environment interaction. | Suisman JL et al. | β | 2011 | β |
| Pre-ejection period reactivity and psychiatric comorbidity prospectively predict substance use initiation among middle-schoolers: a pilot study. | Brenner SL et al. | β | 2011 | β |
| Psychometric and genetic architecture of substance use disorder and behavioral disinhibition measures for gene association studies. | Hicks BM et al. | β | 2011 | β |
| Returns to education: what do twin studies control? | Stanek KC et al. | β | 2011 | β |
| Strategies for characterizing complex phenotypes and environments: general and specific family environmental predictors of young adult tobacco dependence, alcohol use disorder, and co-occurring problems. | Bailey JA et al. | β | 2011 | β |
| Testing the role of adolescent sexual initiation in later-life sexual risk behavior: a longitudinal twin design. | Huibregtse BM et al. | β | 2011 | β |
| The social norms of birth cohorts and adolescent marijuana use in the United States, 1976-2007. | Keyes KM et al. | β | 2011 | β |
| Understanding general and specific connections between psychopathology and marital distress: a model based approach. | South SC et al. | β | 2011 | β |
| Age differences in genetic and environmental influences on weight and shape concerns. | Klump KL et al. | β | 2010 | β |
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| A self-regulatory model of behavioral disinhibition in late adolescence: integrating personality traits, externalizing psychopathology, and cognitive capacity. | Bogg T et al. | β | 2010 | β |
| Changes in genetic and environmental influences on the development of nicotine dependence and major depressive disorder from middle adolescence to early adulthood. | Tully EC et al. | β | 2010 | β |
| Consequences of an adolescent onset and persistent course of alcohol dependence in men: adolescent risk factors and adult outcomes. | Hicks BM et al. | β | 2010 | β |
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| Does marriage inhibit antisocial behavior?: An examination of selection vs causation via a longitudinal twin design. | Burt SA et al. | β | 2010 | β |
| Evidence for genes on chromosome 2 contributing to alcohol dependence with conduct disorder and suicide attempts. | Dick DM et al. | β | 2010 | β |
| Externalizing psychopathology and marital adjustment in long-term marriages: results from a large combined sample of married couples. | Humbad MN et al. | β | 2010 | β |
| Familial loading for alcoholism and offspring behavior: mediating and moderating influences. | Molina BS et al. | β | 2010 | β |
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| For distinguished contributions to psychophysiology: William G. Iacono. | Miller GA | β | 2010 | β |
| Incentive-elicited mesolimbic activation and externalizing symptomatology in adolescents. | Bjork JM et al. | β | 2010 | β |
| Locating eating pathology within an empirical diagnostic taxonomy: evidence from a community-based sample. | Forbush KT et al. | β | 2010 | β |
| Longitudinal associations between depression and substance dependence from adolescence through early adulthood. | Marmorstein NR et al. | β | 2010 | β |
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| Mothers' maximum drinks ever consumed in 24 hours predicts mental health problems in adolescent offspring. | Malone SM et al. | β | 2010 | β |
| Preliminary evidence that estradiol moderates genetic influences on disordered eating attitudes and behaviors during puberty. | Klump KL et al. | β | 2010 | β |
| Psychological flexibility as a fundamental aspect of health. | Kashdan TB et al. | β | 2010 | β |
| Relations of Temperament to Maladjustment and Ego Resiliency in At-Risk Children. | Eisenberg N et al. | β | 2010 | β |
| Specificity of P3 event-related potential reactivity to alcohol cues in individuals low in alcohol sensitivity. | Bartholow BD et al. | β | 2010 | β |
| The heritability of general cognitive ability increases linearly from childhood to young adulthood. | Haworth CM et al. | β | 2010 | β |
| Understanding the construct of impulsivity and its relationship to alcohol use disorders. | Dick DM et al. | β | 2010 | β |
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| Affective decision-making predictive of Chinese adolescent drinking behaviors. | Xiao L et al. | β | 2009 | β |
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| A twin study of the genetics of high cognitive ability selected from 11,000 twin pairs in six studies from four countries. | Haworth CM et al. | β | 2009 | β |
| Environmental adversity and increasing genetic risk for externalizing disorders. | Hicks BM et al. | β | 2009 | β |
| Factorial invariance of the Dyadic Adjustment Scale across gender. | South SC et al. | β | 2009 | β |
| Gene-environment interplay in internalizing disorders: consistent findings across six environmental risk factors. | Hicks BM et al. | β | 2009 | β |
| Genetic and Environmental Transactions Underlying Educational Attainment. | Johnson W et al. | β | 2009 | β |
| How Intelligence and Education Contribute to Substance Use: Hints from the Minnesota Twin Family Study. | Johnson W et al. | β | 2009 | β |
| Nonshared environmental mediation of the association between deviant peer affiliation and adolescent externalizing behaviors over time: results from a cross-lagged monozygotic twin differences design. | Burt SA et al. | β | 2009 | β |
| Parental psychopathology and migraine headaches among adolescent girls. | Marmorstein NR et al. | β | 2009 | β |
| Predictors of illicit substance dependence among individuals with alcohol dependence. | Sintov ND et al. | β | 2009 | β |
| Puberty and the genetic diathesis of disordered eating attitudes and behaviors. | Culbert KM et al. | β | 2009 | β |
| School performance and genetic and environmental variance in antisocial behavior at the transition from adolescence to adulthood. | Johnson W et al. | β | 2009 | β |
| Self-esteem, negative emotionality, and depression as a common temperamental core: a study of mid-adolescent twin girls. | Neiss MB et al. | β | 2009 | β |
| Shared-environmental contributions to high cognitive ability. | Kirkpatrick RM et al. | β | 2009 | β |
| Stability, change, and heritability of borderline personality disorder traits from adolescence to adulthood: a longitudinal twin study. | Bornovalova MA et al. | β | 2009 | β |
| The enrichment study of the Minnesota twin family study: increasing the yield of twin families at high risk for externalizing psychopathology. | Keyes MA et al. | β | 2009 | β |
| The heritability of P300 amplitude in 18-year-olds is robust to adolescent alcohol use. | Perlman G et al. | β | 2009 | β |
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| An adoption study of parental depression as an environmental liability for adolescent depression and childhood disruptive disorders. | Tully EC et al. | β | 2008 | β |
| A neo-Eysenckian personality psychology for the 21st century: conceptualization, etiology, structure, and clinical implications. Introduction to the special issue. | Krueger RF et al. | β | 2008 | β |
| Association of candidate genes with antisocial drug dependence in adolescents. | Corley RP et al. | β | 2008 | β |
| Child and adolescent externalizing behavior and cannabis use disorders in early adulthood: an Australian prospective birth cohort study. | Hayatbakhsh MR et al. | β | 2008 | β |
| Deviant P300 amplitude development in males is associated with paternal externalizing psychopathology. | Carlson SR et al. | β | 2008 | β |
| Early cannabis use and DSM-IV nicotine dependence: a twin study. | Agrawal A et al. | β | 2008 | β |
| Father-child transmission of antisocial behavior: the moderating role of father's presence in the home. | Blazei RW et al. | β | 2008 | β |
| Incentive-elicited striatal activation in adolescent children of alcoholics. | Bjork JM et al. | β | 2008 | β |
| Moderating Effects of Personality on the Genetic and Environmental Influences of School Grades Helps to Explain Sex Differences in Scholastic Achievement. | Hicks BM et al. | β | 2008 | β |
| Prospective associations between depressive symptoms and eating disorder symptoms among adolescent girls. | Marmorstein NR et al. | β | 2008 | β |
| Psychiatric comorbidity in older long-term abstinent alcoholics. | Fein G et al. | β | 2008 | β |
| Rural environments reduce the genetic influence on adolescent substance use and rule-breaking behavior. | Legrand LN et al. | β | 2008 | β |
| Stability and change in personality traits from late adolescence to early adulthood: a longitudinal twin study. | Blonigen DM et al. | β | 2008 | β |
| Strengthening the case: prenatal alcohol exposure is associated with increased risk for conduct disorder. | Disney ER et al. | β | 2008 | β |
| The adolescent origins of substance use disorders. | McGue M et al. | β | 2008 | β |
| The heritability of personality is not always 50%: gene-environment interactions and correlations between personality and parenting. | Krueger RF et al. | β | 2008 | β |
| The role of internalizing and externalizing liability factors in accounting for gender differences in the prevalence of common psychopathological syndromes. | Kramer MD et al. | β | 2008 | β |
| Adolescent psychopathy features: 6-year temporal stability and the prediction of externalizing symptoms during the transition to adulthood. | Loney BR et al. | β | 2007 | β |
| A test of three alternative hypotheses regarding the effects of early delinquency on adolescent psychosocial functioning and substance involvement. | Mason WA et al. | β | 2007 | β |
| Clinical outcomes of laboratory-observed preschool behavioral disinhibition at five-year follow-up. | Hirshfeld-Becker DR et al. | β | 2007 | β |
| Decomposing delta, theta, and alpha time-frequency ERP activity from a visual oddball task using PCA. | Bernat EM et al. | β | 2007 | β |
| Early onset problem behavior, young adult psychopathology, and contextual risk. | Keyes MA et al. | β | 2007 | β |
| Further investigation of psychological and environmental correlates of substance use in adolescence in six European countries. | Kokkevi AE et al. | β | 2007 | β |
| Gender differences and developmental change in externalizing disorders from late adolescence to early adulthood: A longitudinal twin study. | Hicks BM et al. | β | 2007 | β |
| Genes mediate the association between P3 amplitude and externalizing disorders. | Hicks BM et al. | β | 2007 | β |
| How Parents Influence School Grades: Hints from a Sample of Adoptive and Biological Families. | Johnson W et al. | β | 2007 | β |
| Impulsivity and chronic stress are associated with amphetamine-induced striatal dopamine release. | Oswald LM et al. | β | 2007 | β |
| Longitudinal associations between externalizing behavior and dysfunctional eating attitudes and behaviors: a community-based study. | Marmorstein NR et al. | β | 2007 | β |
| Mendelian randomization: a novel test of the gateway hypothesis and models of gene-environment interplay. | Irons DE et al. | β | 2007 | β |
| Personality trait differences in boys and girls with clinical or sub-clinical diagnoses of conduct disorder versus antisocial personality disorder. | Taylor J et al. | β | 2007 | β |
| Psychosocial correlates of substance use in adolescence: a cross-national study in six European countries. | Kokkevi A et al. | β | 2007 | β |
| Psychosocial predictors of sexual initiation and high-risk sexual behaviors in early adolescence. | Caminis A et al. | β | 2007 | β |
| Socioeconomic Status and School Grades: Placing their Association in Broader Context in a Sample of Biological and Adoptive Families. | Johnson W et al. | β | 2007 | β |
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| The different origins of stability and change in antisocial personality disorder symptoms. | Burt SA et al. | β | 2007 | β |
| The environments of adopted and non-adopted youth: evidence on range restriction from the Sibling Interaction and Behavior Study (SIBS). | McGue M et al. | β | 2007 | β |
| The role of conduct disorder in explaining the comorbidity between alcohol and illicit drug dependence in adolescence. | Button TM et al. | β | 2007 | β |
| Association between P3 event-related brain potential amplitude and adolescent problem behavior. | Iacono WG et al. | β | 2006 | β |
| Behavioral and emotional self-control: relations to substance use in samples of middle and high school students. | Wills TA et al. | β | 2006 | β |
| Challenges in genetic studies of the etiology of substance use and substance use disorders: introduction to the special issue. | Prescott CA et al. | β | 2006 | β |
| College drinking behaviors: mediational links between parenting styles, impulse control, and alcohol-related outcomes. | Patock-Peckham JA et al. | β | 2006 | β |
| Continuity and change in psychopathic traits as measured via normal-range personality: a longitudinal-biometric study. | Blonigen DM et al. | β | 2006 | β |
| Differential parent-child relationships and adolescent externalizing symptoms: cross-lagged analyses within a monozygotic twin differences design. | Burt SA et al. | β | 2006 | β |
| Different lengths of times for progressions in adolescent substance involvement. | Ridenour TA et al. | β | 2006 | β |
| Evaluating models of the personality-psychopathology relationship in children and adolescents. | Tackett JL | β | 2006 | β |
| Genetic and environmental influences on academic achievement trajectories during adolescence. | Johnson W et al. | β | 2006 | β |
| Impaired oculomotor response inhibition in children of alcoholics: The role of attention deficit hyperactivity disorder. | Habeych ME et al. | β | 2006 | β |
| Individual differences in childhood neurobehavior disinhibition predict decision to desist substance use during adolescence and substance use disorder in young adulthood: a prospective study. | Kirisci L et al. | β | 2006 | β |
| Laboratory-observed behavioral disinhibition in the young offspring of parents with bipolar disorder: a high-risk pilot study. | Hirshfeld-Becker DR et al. | β | 2006 | β |
| Linking substance use and problem behavior across three generations. | Bailey JA et al. | β | 2006 | β |
| Marital interaction in alcoholic and nonalcoholic couples: alcoholic subtype variations and wives' alcoholism status. | Floyd FJ et al. | β | 2006 | β |
| Minnesota Center for Twin and Family Research. | Iacono WG et al. | β | 2006 | β |
| P300 amplitude as an indicator of externalizing in adolescent males. | Patrick CJ et al. | β | 2006 | β |
| Polydrug abusers display impaired discrimination-reversal learning in a model of behavioural control. | Fillmore MT et al. | β | 2006 | β |
| Schedule-induced electrodermal responding in children. | Latzman RD et al. | β | 2006 | β |
| The association of early adolescent problem behavior and adult psychopathology: a multivariate behavioral genetic perspective. | McGue M et al. | β | 2006 | β |
| The developmental behavior genetics of drug involvement: overview and comments. | Zucker RA | β | 2006 | β |
| Timing of menarche and the origins of conduct disorder. | Burt SA et al. | β | 2006 | β |
| Using the brain P300 response to identify novel phenotypes reflecting genetic vulnerability for adolescent substance misuse. | Yoon HH et al. | β | 2006 | β |
| Detection of youth at high risk for substance use disorders: a longitudinal study. | Kirisci L et al. | β | 2005 | β |
| Direct and mediated associations between P300 amplitude in childhood and substance use disorders outcome in young adulthood. | Habeych ME et al. | β | 2005 | β |
| Estimating facets of psychopathy from normal personality traits: a step toward community epidemiological investigations. | Benning SD et al. | β | 2005 | β |
| Externalizing psychopathology in adulthood: a dimensional-spectrum conceptualization and its implications for DSM-V. | Krueger RF et al. | β | 2005 | β |
| How are parent-child conflict and childhood externalizing symptoms related over time? Results from a genetically informative cross-lagged study. | Burt SA et al. | β | 2005 | β |
| Longitudinal follow-up of adolescents with late-onset antisocial behavior: a pathological yet overlooked group. | Marmorstein NR et al. | β | 2005 | β |
| Perceptions of the parent-adolescent relationship: a longitudinal investigation. | McGue M et al. | β | 2005 | β |
| Psychopathic personality traits: heritability and genetic overlap with internalizing and externalizing psychopathology. | Blonigen DM et al. | β | 2005 | β |
| Psychopathy, startle blink modulation, and electrodermal reactivity in twin men. | Benning SD et al. | β | 2005 | β |
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| Sources of covariation among the child-externalizing disorders: informant effects and the shared environment. | Burt SA et al. | β | 2005 | β |
| Spatial-anatomical mapping of NoGo-P3 in the offspring of alcoholics: evidence of cognitive and neural disinhibition as a risk for alcoholism. | Kamarajan C et al. | β | 2005 | β |
| Symptom-based subfactors of DSM-defined conduct disorder: evidence for etiologic distinctions. | Tackett JL et al. | β | 2005 | β |
| The association of early adolescent problem behavior with adult psychopathology. | McGue M et al. | β | 2005 | β |
| The Minnesota Eating Behavior Survey: a brief measure of disordered eating attitudes and behaviors. | von Ranson KM et al. | β | 2005 | β |
| The P3 in 'ecstasy' polydrug users during response inhibition and execution. | Gamma A et al. | β | 2005 | β |
| Childhood externalizing and internalizing psychopathology in the prediction of early substance use. | King SM et al. | β | 2004 | β |
| Cross-generational effects on gender differences in psychoactive drug abuse and dependence. | Holdcraft LC et al. | β | 2004 | β |
| Gene-environment interplay in alcoholism and other substance abuse disorders: expressions of heritability and factors influencing vulnerability. | Palomo T et al. | β | 2004 | β |
| Genetic and environmental influences on antisocial behavior and alcohol dependence from adolescence to early adulthood. | Malone SM et al. | β | 2004 | β |
| Identifying shared environmental contributions to early substance use: the respective roles of peers and parents. | Walden B et al. | β | 2004 | β |
| Major depression and conduct disorder in youth: associations with parental psychopathology and parent-child conflict. | Marmorstein NR et al. | β | 2004 | β |
| Mismatch negativity: no difference between controls and abstinent alcoholics. | Fein G et al. | β | 2004 | β |
| Models of co-occurring substance misuse and psychosis: are personality traits the missing link? | Hides L et al. | β | 2004 | β |
| Neurobehavior disinhibition in childhood predisposes boys to substance use disorder by young adulthood: direct and mediated etiologic pathways. | Tarter RE et al. | β | 2004 | β |
| P300 amplitude in nonalcoholic adolescent twin pairs who become discordant for alcoholism as adults. | Carlson SR et al. | β | 2004 | β |
| Psychiatric disorders among offspring of depressed mothers: associations with paternal psychopathology. | Marmorstein NR et al. | β | 2004 | β |
| The effect of parental alcohol and drug disorders on adolescent personality. | Elkins IJ et al. | β | 2004 | β |
| A genome-wide search for quantitative trait loci influencing substance dependence vulnerability in adolescence. | Stallings MC et al. | β | 2003 | β |
| Differential heritability of eating attitudes and behaviors in prepubertal versus pubertal twins. | Klump KL et al. | β | 2003 | β |
| Factor structure of the psychopathic personality inventory: validity and implications for clinical assessment. | Benning SD et al. | β | 2003 | β |
| Familial transmission of Continuous Performance Test behavior: attentional and impulsive response characteristics. | Dougherty DM et al. | β | 2003 | β |
| Genetic and environmental influences on psychopathy trait dimensions in a community sample of male twins. | Taylor J et al. | β | 2003 | β |
| Major depression and conduct disorder in a twin sample: gender, functioning, and risk for future psychopathology. | Marmorstein NR et al. | β | 2003 | β |
| Neurological soft signs and disruptive behavior among children of opiate dependent parents. | Wilson JJ et al. | β | 2003 | β |
| Review of twin and adoption studies of adolescent substance use. | Hopfer CJ et al. | β | 2003 | β |
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| Dependency, impulsivity, and self-harm: traits hypothesized to underlie the association between cluster B personality and substance use disorders. | Casillas A et al. | β | 2002 | β |
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| Motivation, working memory, and decision making: a cognitive-motivational theory of personality vulnerability to alcoholism. | Finn PR | β | 2002 | β |
| P300 amplitude in adolescent twins discordant and concordant for alcohol use disorders. | Carlson SR et al. | β | 2002 | β |
| The association between psychopathology in fathers versus mothers and children's internalizing and externalizing behavior problems: a meta-analysis. | Connell AM et al. | β | 2002 | β |
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| An investigation of female adolescent twins with both major depression and conduct disorder. | Marmorstein NR et al. | β | 2001 | β |
| Constraint, alcoholism, and electrodermal response in aversive classical conditioning and mismatch novelty paradigms. | Finn PR et al. | β | 2001 | β |
| Do genetic factors contribute to the association between birth weight and blood pressure? | Christensen K et al. | β | 2001 | β |
| Origins and consequences of age at first drink. I. Associations with substance-use disorders, disinhibitory behavior and psychopathology, and P3 amplitude. | McGue M et al. | β | 2001 | β |
| Origins and consequences of age at first drink. II. Familial risk and heritability. | McGue M et al. | β | 2001 | β |
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| Searching for interactive effects in the etiology of early-onset substance use. | Legrand LN et al. | β | 1999 | β |