Chrna6 gene

Aliases: alpha-6 subunit, α6, α6 subunit, α6 subunit gene, α6-containing nAChRs
External links: NCBI Gene · Ensembl · GeneCards · UniProt

Evidence from: primary | all sources

Related entities (28)

Subject	Relation	Object	p-value	Evidence
Chrna6	risk_factor_for	alcohol dependence	—	1
Chrna6	expressed_in	brain	—	1
Chrna6	interacts_with	Chrnb3	—	1
Chrna6	associated_with	cigarettes	—	1
Chrna6	risk_factor_for	cocaine	—	1
Chrna6	associated_with	current smoking	—	1
Chrna6	regulates	dopamine	—	1
Chrna6	expressed_in	dopaminergic neurons	—	1
Chrna6	associated_with	ever smoking	—	1
Chrna6	associated_with	former smokers	—	1
Chrna6	expressed_in	locus coeruleus	—	1
Chrna6	associated_with	lung cancer	—	1
Chrna6	associated_with	never smokers	—	1
Chrna6	associated_with	nicotine	—	6
Chrna6	risk_factor_for	nicotine	—	3
Chrna6	associated_with	nicotine reward	—	1
Chrna6	associated_with	nicotine withdrawal	—	2
Chrna6	expressed_in	nicotinic acetylcholine receptor	—	1
Chrna6	associated_with	smoking abstinence	—	1
Chrna6	associated_with	smoking behavior	—	1
Chrna6	associated_with	smoking cessation	—	1
Chrna6	expressed_in	striatum	—	1
Chrna6	risk_factor_for	substance abuse	—	1
Chrna6	expressed_in	ventral tegmental area	—	1
Chrnb3	regulates	Chrna6	—	1
Chrnb3	interacts_with	Chrna6	—	1
nicotine	regulates	Chrna6	—	1
nicotine	interacts_with	Chrna6	—	1

Mentioned in (16)

Papers in which this entity is mentioned.

Effects of nicotinic acetylcholine receptor-activating alkaloids on anxiety-like behavior in zebrafish. (2021)
Cotinine: Pharmacologically Active Metabolite of Nicotine and Neural Mechanisms for Its Actions. (2021)
Human Genetics of Addiction: New Insights and Future Directions. (2018)
Molecular Diversity and Specializations among the Cells of the Adult Mouse Brain. (2018)
Neuronal Nicotinic Acetylcholine Receptor Structure and Function and Response to Nicotine. (2015)
Identification of CHRNA5 rare variants in African-American heavy smokers. (2014)
Acetylcholine as a neuromodulator: cholinergic signaling shapes nervous system function and behavior. (2012)
Pharmacogenetics of smoking cessation: role of nicotine target and metabolism genes. (2012)
Assessing the impact of nicotine dependence genes on the risk of facial clefts: An example of the use of national registry and biobank data. (2012)
Genetic polymorphisms in 15q25 and 19q13 loci, cotinine levels, and risk of lung cancer in EPIC. (2011)
Convergence of genetic findings for nicotine dependence and smoking related diseases with chromosome 15q24-25. (2010)
Multiple cholinergic nicotinic receptor genes affect nicotine dependence risk in African and European Americans. (2010)
New insights into the genetics of addiction. (2009)
Nicotinic acetylcholine receptor beta2 subunit gene implicated in a systems-based candidate gene study of smoking cessation. (2008)
Association of a single nucleotide polymorphism in neuronal acetylcholine receptor subunit alpha 5 (CHRNA5) with smoking status and with 'pleasurable buzz' during early experimentation with smoking. (2008)
Nicotinic receptors mediate changes in spinal motoneuron development and axonal pathfinding in embryonic zebrafish exposed to nicotine. (2002)

Merged raw entities (4)

All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.

Raw name	Type	Papers	Mentions
chrna6	gene	16	35
alpha-6 subunit	gene	—	—
α6-containing nachrs	gene	—	—
α6 subunit gene	gene	—	—