5HTTLPR variant
Evidence from:
primary |
all sources
Related entities (15)
| Subject | Relation | Object | p-value | Evidence |
|---|---|---|---|---|
| 5HTTLPR | regulates | amygdala | — | 1 |
| 5HTTLPR | associated_with | depression | — | 1 |
| 5HTTLPR | risk_factor_for | depression | — | 1 |
| 5HTTLPR | risk_factor_for | externalizing disorders | — | 1 |
| 5HTTLPR | protective_against | externalizing disorders | — | 1 |
| 5HTTLPR | associated_with | healthy controls | — | 1 |
| 5HTTLPR | associated_with | MD | — | 1 |
| 5HTTLPR | regulates | medial prefrontal cortex | — | 1 |
| 5HTTLPR | risk_factor_for | mood disorders | — | 1 |
| 5HTTLPR | interacts_with | physical abuse | 0.0001 | 1 |
| 5HTTLPR | associated_with | SLC6A4 | — | 1 |
| 5HTTLPR | regulates | SLC6A4 | — | 1 |
| 5HTTLPR | interacts_with | social support | — | 1 |
| 5HTTLPR | interacts_with | stressful life events | — | 1 |
| 5HTTLPR | associated_with | suicide | — | 1 |
Mentioned in (9)
Papers in which this entity is mentioned.
- Effects of early life stress on amygdala and striatal development. (2016)
- Candidate gene-environment interaction research: reflections and recommendations. (2015)
- Is the gene-environment interaction paradigm relevant to genome-wide studies? The case of education and body mass index. (2014)
- Gene × environment interaction studies have not properly controlled for potential confounders: the problem and the (simple) solution. (2014)
- Maternal anxiety and infants' hippocampal development: timing matters. (2013)
- Genome-wide association study of major depressive disorder: new results, meta-analysis, and lessons learned. (2012)
- The neuroscience of suicidal behaviors: what can we expect from endophenotype strategies? (2011)
- Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression: a meta-analysis. (2009)
- The relationship of 5HTT (SLC6A4) methylation and genotype on mRNA expression and liability to major depression and alcohol dependence in subjects from the Iowa Adoption Studies. (2008)
Merged raw entities (9)
All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.
| Raw name | Type | Papers | Mentions |
|---|---|---|---|
| 5httlpr | variant | 9 | 25 |
| 5htt linked polymorphic region | variant | — | — |
| 5httlpr genotype | variant | — | — |
| serotonin transporter linked polymorphic region | variant | — | — |
| serotonin transporter-linked polymorphic region | variant | — | — |
| serotonin-transporter-linked polymorphic region | variant | — | — |
| serotonin transporter promoter polymorphism | variant | — | — |
| serotonin transporter promoter variant | variant | — | — |
| short allele of 5httlpr | variant | — | — |