Chrnb3 gene
Evidence from:
primary |
all sources
Related entities (23)
| Subject | Relation | Object | p-value | Evidence |
|---|---|---|---|---|
| CHRNA5 | interacts_with | Chrnb3 | — | 1 |
| Chrna6 | interacts_with | Chrnb3 | — | 1 |
| Chrnb3 | risk_factor_for | alcohol dependence | — | 1 |
| Chrnb3 | regulates | Chrna6 | — | 1 |
| Chrnb3 | interacts_with | Chrna6 | — | 1 |
| Chrnb3 | associated_with | cigarettes | — | 1 |
| Chrnb3 | risk_factor_for | cocaine | — | 1 |
| Chrnb3 | associated_with | current smoking | — | 1 |
| Chrnb3 | expressed_in | dopaminergic neurons | — | 1 |
| Chrnb3 | associated_with | ever smoking | — | 1 |
| Chrnb3 | associated_with | former smokers | — | 1 |
| Chrnb3 | associated_with | lung cancer | — | 1 |
| Chrnb3 | associated_with | never smokers | — | 1 |
| Chrnb3 | risk_factor_for | nicotine | — | 3 |
| Chrnb3 | associated_with | nicotine | — | 6 |
| Chrnb3 | associated_with | nicotine withdrawal | — | 1 |
| Chrnb3 | expressed_in | nicotinic acetylcholine receptor | — | 1 |
| Chrnb3 | associated_with | nicotinic acetylcholine receptor | — | 1 |
| Chrnb3 | associated_with | smoking abstinence | — | 1 |
| Chrnb3 | associated_with | smoking behavior | — | 1 |
| Chrnb3 | associated_with | smoking cessation | — | 1 |
| Chrnb3 | risk_factor_for | substance abuse | — | 1 |
| nicotine | interacts_with | Chrnb3 | — | 1 |
Mentioned in (18)
Papers in which this entity is mentioned.
- Effects of nicotinic acetylcholine receptor-activating alkaloids on anxiety-like behavior in zebrafish. (2021)
- Cotinine: Pharmacologically Active Metabolite of Nicotine and Neural Mechanisms for Its Actions. (2021)
- Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences. (2019)
- Human Genetics of Addiction: New Insights and Future Directions. (2018)
- Molecular Diversity and Specializations among the Cells of the Adult Mouse Brain. (2018)
- Dissecting ancestry genomic background in substance dependence genome-wide association studies. (2015)
- Neuronal Nicotinic Acetylcholine Receptor Structure and Function and Response to Nicotine. (2015)
- Identification of CHRNA5 rare variants in African-American heavy smokers. (2014)
- Acetylcholine as a neuromodulator: cholinergic signaling shapes nervous system function and behavior. (2012)
- Pharmacogenetics of smoking cessation: role of nicotine target and metabolism genes. (2012)
- Assessing the impact of nicotine dependence genes on the risk of facial clefts: An example of the use of national registry and biobank data. (2012)
- Genetic polymorphisms in 15q25 and 19q13 loci, cotinine levels, and risk of lung cancer in EPIC. (2011)
- Convergence of genetic findings for nicotine dependence and smoking related diseases with chromosome 15q24-25. (2010)
- Multiple cholinergic nicotinic receptor genes affect nicotine dependence risk in African and European Americans. (2010)
- New insights into the genetics of addiction. (2009)
- Nicotinic acetylcholine receptor beta2 subunit gene implicated in a systems-based candidate gene study of smoking cessation. (2008)
- Association of a single nucleotide polymorphism in neuronal acetylcholine receptor subunit alpha 5 (CHRNA5) with smoking status and with 'pleasurable buzz' during early experimentation with smoking. (2008)
- Nicotinic receptors mediate changes in spinal motoneuron development and axonal pathfinding in embryonic zebrafish exposed to nicotine. (2002)
Merged raw entities (3)
All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.
| Raw name | Type | Papers | Mentions |
|---|---|---|---|
| chrnb3 | gene | 18 | 34 |
| beta-3 subunit | gene | — | — |
| β3 subunit gene | gene | — | — |