apoE gene
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Related entities (33)
Mentioned in (100)
Papers in which this entity is mentioned.
- Reduction of APOE accounts for neurobehavioral deficits in fetal alcohol spectrum disorders. (2024)
- Epsin Nanotherapy Regulates Cholesterol Transport to Fortify Atheroma Regression. (2023)
- A DNA methylation atlas of normal human cell types. (2023)
- Apolipoprotein E intersects with amyloid-β within neurons. (2023)
- Pitfalls of predicting age-related traits by polygenic risk scores. (2023)
- Predicting Alcohol-Related Memory Problems in Older Adults: A Machine Learning Study with Multi-Domain Features. (2023)
- Pervasive Downward Bias in Estimates of Liability-Scale Heritability in Genome-wide Association Study Meta-analysis: A Simple Solution. (2023)
- Genetic Influences on the Developing Young Brain and Risk for Neuropsychiatric Disorders. (2023)
- Epigenetics in Alzheimer's Disease. (2022)
- Global Biobank Meta-analysis Initiative: Powering genetic discovery across human disease. (2022)
- The pro-apoptotic Bax gene modifies susceptibility to craniofacial dysmorphology following gastrulation-stage alcohol exposure. (2022)
- Genetic variants associated with longitudinal changes in brain structure across the lifespan. (2022)
- Large-scale collaboration in ENIGMA-EEG: A perspective on the meta-analytic approach to link neurological and psychiatric liability genes to electrophysiological brain activity. (2021)
- A novel missense variant in ACAA1 contributes to early-onset Alzheimer's disease, impairs lysosomal function, and facilitates amyloid-β pathology and cognitive decline. (2021)
- Neurotoxic reactive astrocytes induce cell death via saturated lipids. (2021)
- Mitochondria-dependent phase separation of disease-relevant proteins drives pathological features of age-related macular degeneration. (2021)
- Neuronal ApoE upregulates MHC-I expression to drive selective neurodegeneration in Alzheimer's disease. (2021)
- Inference and analysis of cell-cell communication using CellChat. (2021)
- Interpretation of risk loci from genome-wide association studies of Alzheimer's disease. (2020)
- Polygenic risk scores: from research tools to clinical instruments. (2020)
- Tead transcription factors differentially regulate cortical development. (2020)
- Longitudinal ComBat: A method for harmonizing longitudinal multi-scanner imaging data. (2020)
- Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson's disease. (2020)
- Longitudinal white matter and cognitive development in pediatric carriers of the apolipoprotein ε4 allele. (2020)
- ASEP: Gene-based detection of allele-specific expression across individuals in a population by RNA sequencing. (2020)
- Astrocyte Reactivity: Subtypes, States, and Functions in CNS Innate Immunity. (2020)
- Transcriptomic signatures across human tissues identify functional rare genetic variation. (2020)
- Defining the Genetic, Genomic, Cellular, and Diagnostic Architectures of Psychiatric Disorders. (2019)
- A review on neuroimaging studies of genetic and environmental influences on early brain development. (2019)
- Psychiatric Genomics: An Update and an Agenda. (2018)
- Gain of toxic apolipoprotein E4 effects in human iPSC-derived neurons is ameliorated by a small-molecule structure corrector. (2018)
- Imaging structural and functional brain development in early childhood. (2018)
- ApoE Regulates the Development of Adult Newborn Hippocampal Neurons. (2018)
- The development of brain white matter microstructure. (2018)
- Gene-environment interactions in development and disease. (2017)
- ApoE, ApoE Receptors, and the Synapse in Alzheimer's Disease. (2017)
- Efficient derivation of microglia-like cells from human pluripotent stem cells. (2016)
- Gray matter maturation and cognition in children with different APOE ε genotypes. (2016)
- Three Dimensional Human Neuro-Spheroid Model of Alzheimer's Disease Based on Differentiated Induced Pluripotent Stem Cells. (2016)
- Self-Organizing 3D Human Neural Tissue Derived from Induced Pluripotent Stem Cells Recapitulate Alzheimer's Disease Phenotypes. (2016)
- Genetic Restoration of Plasma ApoE Improves Cognition and Partially Restores Synaptic Defects in ApoE-Deficient Mice. (2016)
- Alcohol Use During Pregnancy is Associated with Specific Alterations in MicroRNA Levels in Maternal Serum. (2016)
- Possible relationship between common genetic variation and white matter development in a pilot study of preterm infants. (2016)
- Glymphatic distribution of CSF-derived apoE into brain is isoform specific and suppressed during sleep deprivation. (2016)
- Direct Transcriptional Effects of Apolipoprotein E. (2016)
- Low Density Lipoprotein Receptor Related Proteins as Regulators of Neural Stem and Progenitor Cell Function. (2016)
- Fetal Alcohol Spectrum Disorders: An Overview from the Glia Perspective. (2015)
- An introductory review of parallel independent component analysis (p-ICA) and a guide to applying p-ICA to genetic data and imaging phenotypes to identify disease-associated biological pathways and systems in common complex disorders. (2015)
- Candidate gene-environment interaction research: reflections and recommendations. (2015)
- Evaluating historical candidate genes for schizophrenia. (2015)
- The Effects of Arsenic Exposure on Neurological and Cognitive Dysfunction in Human and Rodent Studies: A Review. (2014)
- The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data. (2014)
- Neuroinflammation and M2 microglia: the good, the bad, and the inflamed. (2014)
- The CXCL12/CXCR4 chemokine ligand/receptor axis in cardiovascular disease. (2014)
- Heritability and molecular-genetic basis of resting EEG activity: a genome-wide association study. (2014)
- Genetic influences on brain developmental trajectories on neuroimaging studies: from infancy to young adulthood. (2014)
- Brain differences in infants at differential genetic risk for late-onset Alzheimer disease: a cross-sectional imaging study. (2014)
- Common variants in psychiatric risk genes predict brain structure at birth. (2014)
- New therapeutic approaches for Alzheimer's disease and cerebral amyloid angiopathy. (2014)
- Physical exercise-induced adult neurogenesis: a good strategy to prevent cognitive decline in neurodegenerative diseases? (2014)
- NIH toolbox for assessment of neurological and behavioral function. (2013)
- Neurodevelopmental alcohol exposure elicits long-term changes to gene expression that alter distinct molecular pathways dependent on timing of exposure. (2013)
- ApoE4 induces Aβ42, tau, and neuronal pathology in the hippocampus of young targeted replacement apoE4 mice. (2013)
- Long-lasting alterations to DNA methylation and ncRNAs could underlie the effects of fetal alcohol exposure in mice. (2013)
- Bridging animal and human models of exercise-induced brain plasticity. (2013)
- In vivo and in vitro effects of an apolipoprotein e mimetic peptide on amyloid-β pathology. (2013)
- Statistical analysis of longitudinal neuroimage data with Linear Mixed Effects models. (2013)
- Amyloid pathway-based candidate gene analysis of [(11)C]PiB-PET in the Alzheimer's Disease Neuroimaging Initiative (ADNI) cohort. (2012)
- Apolipoprotein E does not cross the blood-cerebrospinal fluid barrier, as revealed by an improved technique for sampling CSF from mice. (2012)
- Resting-state network disruption and APOE genotype in Alzheimer's disease: a lagged functional connectivity study. (2012)
- Managing incidental findings and research results in genomic research involving biobanks and archived data sets. (2012)
- Functional analysis of APOE locus genetic variation implicates regional enhancers in the regulation of both TOMM40 and APOE. (2012)
- MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins. (2011)
- Apolipoprotein E: from lipid transport to neurobiology. (2011)
- Molecular insights into the pathogenesis of Alzheimer's disease and its relationship to normal aging. (2011)
- Transgenic mouse models of Alzheimer's disease. (2010)
- Genetic control over the resting brain. (2010)
- Neuronal LRP1 knockout in adult mice leads to impaired brain lipid metabolism and progressive, age-dependent synapse loss and neurodegeneration. (2010)
- Callosal atrophy in mild cognitive impairment and Alzheimer's disease: different effects in different stages. (2010)
- Obesity is linked with lower brain volume in 700 AD and MCI patients. (2010)
- Structural MRI of pediatric brain development: what have we learned and where are we going? (2010)
- COG1410, an apolipoprotein E-based peptide, improves cognitive performance and reduces cortical loss following moderate fluid percussion injury in the rat. (2010)
- Genome-wide association studies in diverse populations. (2010)
- Whole genome association study of brain-wide imaging phenotypes for identifying quantitative trait loci in MCI and AD: A study of the ADNI cohort. (2010)
- A review of estrogen receptor alpha gene (ESR1) polymorphisms, mood, and cognition. (2010)
- A general factor of brain white matter integrity predicts information processing speed in healthy older people. (2010)
- A genome-wide association study of autism reveals a common novel risk locus at 5p14.1. (2009)
- The future of genetics in psychology and psychiatry: microarrays, genome-wide association, and non-coding RNA. (2009)
- The role of GABA(A) receptors in the acute and chronic effects of ethanol: a decade of progress. (2009)
- Potential role for plasma placental growth factor in predicting coronary heart disease risk in women. (2009)
- Apolipoprotein E-mimetics inhibit neurodegeneration and restore cognitive functions in a transgenic Drosophila model of Alzheimer's disease. (2009)
- Reduced cortical thickness in hippocampal subregions among cognitively normal apolipoprotein E e4 carriers. (2008)
- Multiple SNPs within and surrounding the apolipoprotein E gene influence cerebrospinal fluid apolipoprotein E protein levels. (2008)
- Network analysis of intrinsic functional brain connectivity in Alzheimer's disease. (2008)
- Choline: critical role during fetal development and dietary requirements in adults. (2006)
- Genetic vulnerability following traumatic brain injury: the role of apolipoprotein E. (2003)
- Two distal downstream enhancers direct expression of the human apolipoprotein E gene to astrocytes in the brain. (2001)
- Specific regional transcription of apolipoprotein E in human brain neurons. (1999)
- The role of the medial prefrontal cortex (cingulate gyrus) in the regulation of hypothalamic-pituitary-adrenal responses to stress. (1993)
- Apolipoprotein E associated with astrocytic glia of the central nervous system and with nonmyelinating glia of the peripheral nervous system. (1985)
Merged raw entities (7)
All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.
| Raw name | Type | Papers | Mentions |
|---|---|---|---|
| apoe | gene | 100 | 1092 |
| apolipoprotein e | gene | 1 | 1 |
| apoe-4 | gene | — | — |
| apoe4/4 | gene | — | — |
| apoe-4 allele | gene | — | — |
| apoe susceptibility gene | gene | — | — |
| apolipoprotein e apoe | gene | — | — |