Dlg4 gene
Evidence from:
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all sources
Related entities (22)
| Subject | Relation | Object | p-value | Evidence |
|---|---|---|---|---|
| alcohol | risk_factor_for | Dlg4 | — | 1 |
| Dlg2 | interacts_with | Dlg4 | — | 1 |
| Dlg4 | interacts_with | AMPAR | — | 1 |
| Dlg4 | interacts_with | CACNG2 | — | 1 |
| Dlg4 | expressed_in | central nervous system | — | 1 |
| Dlg4 | interacts_with | Dlgap2 | — | 1 |
| Dlg4 | associated_with | glutamate | — | 1 |
| Dlg4 | regulates | glutamate | — | 1 |
| Dlg4 | interacts_with | GRIN2A | — | 1 |
| Dlg4 | expressed_in | hippocampus | — | 1 |
| Dlg4 | associated_with | morphine | — | 1 |
| Dlg4 | expressed_in | NAc | — | 1 |
| Dlg4 | interacts_with | NMDAR | — | 1 |
| Dlg4 | regulates | Nos1 | — | 1 |
| Dlg4 | associated_with | synaptic plasticity | — | 1 |
| Dlg4 | associated_with | THC | 0.05 | 1 |
| Dlg4 | interacts_with | vGLUT1 | — | 1 |
| drug dependence | risk_factor_for | Dlg4 | — | 1 |
| ethanol group | risk_factor_for | Dlg4 | — | 1 |
| Homer1 | interacts_with | Dlg4 | — | 1 |
| THC | regulates | Dlg4 | — | 1 |
| THC | associated_with | Dlg4 | — | 1 |
Mentioned in (50)
Papers in which this entity is mentioned.
- Massively parallel reporter assay investigates shared genetic variants of eight psychiatric disorders. (2025)
- Reduction of APOE accounts for neurobehavioral deficits in fetal alcohol spectrum disorders. (2024)
- Impact of alcohol exposure on neural development and network formation in human cortical organoids. (2023)
- Alcohol reverses the effects of KCNJ6 (GIRK2) noncoding variants on excitability of human glutamatergic neurons. (2023)
- Genetic Influences on the Developing Young Brain and Risk for Neuropsychiatric Disorders. (2023)
- A novel missense variant in ACAA1 contributes to early-onset Alzheimer's disease, impairs lysosomal function, and facilitates amyloid-β pathology and cognitive decline. (2021)
- PKA and Ube3a regulate SK2 channel trafficking to promote synaptic plasticity in hippocampus: Implications for Angelman Syndrome. (2020)
- A review on neuroimaging studies of genetic and environmental influences on early brain development. (2019)
- SK Channel Modulates Synaptic Plasticity by Tuning CaMKIIα/β Dynamics. (2019)
- Hippocampal deficits in neurodevelopmental disorders. (2019)
- Mental Illnesses-Associated Fxr1 and Its Negative Regulator Gsk3β Are Modulators of Anxiety and Glutamatergic Neurotransmission. (2018)
- Imaging structural and functional brain development in early childhood. (2018)
- Neuroepigenetics and addiction. (2018)
- The Role of the Endocannabinoid System and Genetic Variation in Adolescent Brain Development. (2018)
- Regional Differences and Similarities in the Brain Transcriptome for Mice Selected for Ethanol Preference From HS-CC Founders. (2018)
- Assembly of functionally integrated human forebrain spheroids. (2017)
- Wnt5a is essential for hippocampal dendritic maintenance and spatial learning and memory in adult mice. (2017)
- Integrative genomics of microglia implicates DLG4 (PSD95) in the white matter development of preterm infants. (2017)
- ApoE, ApoE Receptors, and the Synapse in Alzheimer's Disease. (2017)
- H3K9me3 Inhibition Improves Memory, Promotes Spine Formation, and Increases BDNF Levels in the Aged Hippocampus. (2016)
- Rapid Ngn2-induction of excitatory neurons from hiPSC-derived neural progenitor cells. (2016)
- Increasing the GluN2A/GluN2B Ratio in Neurons of the Mouse Basal and Lateral Amygdala Inhibits the Modification of an Existing Fear Memory Trace. (2016)
- Ethanol-Associated Changes in Glutamate Reward Neurocircuitry: A Minireview of Clinical and Preclinical Genetic Findings. (2016)
- Genome-Wide DNA Methylation Profiling Reveals Epigenetic Changes in the Rat Nucleus Accumbens Associated With Cross-Generational Effects of Adolescent THC Exposure. (2015)
- The discovery of integrated gene networks for autism and related disorders. (2015)
- Moderate prenatal alcohol exposure enhances GluN2B containing NMDA receptor binding and ifenprodil sensitivity in rat agranular insular cortex. (2015)
- The Effects of Arsenic Exposure on Neurological and Cognitive Dysfunction in Human and Rodent Studies: A Review. (2014)
- Intersubject variability of and genetic effects on the brain's functional connectivity during infancy. (2014)
- Neurodevelopmental alcohol exposure elicits long-term changes to gene expression that alter distinct molecular pathways dependent on timing of exposure. (2013)
- Low density lipoprotein receptor-related protein 1 (LRP1) modulates N-methyl-D-aspartate (NMDA) receptor-dependent intracellular signaling and NMDA-induced regulation of postsynaptic protein complexes. (2013)
- Cornichon proteins determine the subunit composition of synaptic AMPA receptors. (2013)
- LRP1 is critical for the surface distribution and internalization of the NR2B NMDA receptor subtype. (2013)
- Rethinking schizophrenia in the context of normal neurodevelopment. (2013)
- Moderate prenatal alcohol exposure reduces plasticity and alters NMDA receptor subunit composition in the dentate gyrus. (2013)
- The ubiquitin-proteasome system as a critical regulator of synaptic plasticity and long-term memory formation. (2013)
- DISC1 at 10: connecting psychiatric genetics and neuroscience. (2011)
- Role of ubiquitin-proteasome-mediated proteolysis in nervous system disease. (2011)
- PDZ binding of TARPγ-8 controls synaptic transmission but not synaptic plasticity. (2011)
- Neuronal LRP1 knockout in adult mice leads to impaired brain lipid metabolism and progressive, age-dependent synapse loss and neurodegeneration. (2010)
- "CRASH"ing with the worm: insights into L1CAM functions and mechanisms. (2010)
- Normal development of brain circuits. (2010)
- Loss of GluN2B-containing NMDA receptors in CA1 hippocampus and cortex impairs long-term depression, reduces dendritic spine density, and disrupts learning. (2010)
- Novel roles for immune molecules in neural development: implications for neurodevelopmental disorders. (2010)
- Neuregulin 1 in neural development, synaptic plasticity and schizophrenia. (2008)
- PIASx is a MEF2 SUMO E3 ligase that promotes postsynaptic dendritic morphogenesis. (2007)
- Defects in embryonic neurogenesis and initial synapse formation in the forebrain of the Ts65Dn mouse model of Down syndrome. (2007)
- Structural and functional modifications in glutamateric synapses following prolonged ethanol exposure. (2006)
- Sexually dimorphic synaptic organization of the medial amygdala. (2005)
- Neuronal LRP1 functionally associates with postsynaptic proteins and is required for normal motor function in mice. (2004)
- Relationship between availability of NMDA receptor subunits and their expression at the synapse. (2002)
Merged raw entities (4)
All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.
| Raw name | Type | Papers | Mentions |
|---|---|---|---|
| dlg4 | gene | 42 | 131 |
| psd-95 | gene | 13 | 18 |
| postsynaptic density protein 95 | gene | 1 | 1 |
| psd 95 | gene | — | — |