cDNA drug

Aliases

complementary DNA, second strand cDNA

External links

DrugBank · PubChem

Related entities (10)

Mentioned in (106)

Papers in which this entity is mentioned.

• Single-cell exon deletion profiling reveals splicing events that shape gene expression and cell state dynamics. (2026)
• Tumour-wide RNA splicing aberrations generate actionable public neoantigens. (2025)
• Multi-omic quantitative trait loci link tandem repeat size variation to gene regulation in human brain. (2025)
• Massively parallel reporter assay investigates shared genetic variants of eight psychiatric disorders. (2025)
• Multiple overlapping binding sites determine transcription factor occupancy. (2025)
• Integrated single-cell multiomic profiling of caudate nucleus suggests key mechanisms in alcohol use disorder. (2025)
• Single cell and spatial alternative splicing analysis with Nanopore long read sequencing. (2025)
• Detection and analysis of complex structural variation in human genomes across populations and in brains of donors with psychiatric disorders. (2024)
• Alternative splicing of transcript mediates the response of circadian clocks to temperature changes. (2024)
• The Application of Long-Read Sequencing to Cancer. (2024)
• Single-cell RNA sequencing of peripheral blood links cell-type-specific regulation of splicing to autoimmune and inflammatory diseases. (2024)
• ESPRESSO: Robust discovery and quantification of transcript isoforms from error-prone long-read RNA-seq data. (2023)
• Nanopore sequencing of RNA and cDNA molecules in . (2022)
• Integrated analysis of multimodal single-cell data. (2021)
• Nanopore sequencing technology, bioinformatics and applications. (2021)
• Application of third-generation sequencing in cancer research. (2021)
• Alternative splicing: Human disease and quantitative analysis from high-throughput sequencing. (2021)
• Joint single-cell measurements of nuclear proteins and RNA in vivo. (2021)
• Infant circulating MicroRNAs as biomarkers of effect in fetal alcohol spectrum disorders. (2021)
• Ethanol modulation of hippocampal neuroinflammation, myelination, and neurodevelopment in a postnatal mouse model of fetal alcohol spectrum disorders. (2021)
• Simultaneous single cell measurements of intranuclear proteins and gene expression (2021)
• Simultaneous epigenetic perturbation and genome imaging reveal distinct roles of H3K9me3 in chromatin architecture and transcription. (2020)
• Neonatal Alcohol Exposure in Mice Induces Select Differentiation- and Apoptosis-Related Chromatin Changes Both Independent of and Dependent on Sex. (2020)
• Tead transcription factors differentially regulate cortical development. (2020)
• Gestational diabetes induces behavioral and brain gene transcription dysregulation in adult offspring. (2020)
• Effects of chronic intermittent ethanol exposure and withdrawal on neuroblastoma cell transcriptome. (2020)
• Transcriptomic signatures across human tissues identify functional rare genetic variation. (2020)
• Single-Cell RNA-Seq Reveals AML Hierarchies Relevant to Disease Progression and Immunity. (2019)
• The role and robustness of the Gini coefficient as an unbiased tool for the selection of Gini genes for normalising expression profiling data. (2019)
• Persistent Changes in Stress-Regulatory Genes in Pregnant Women or Children Exposed Prenatally to Alcohol. (2019)
• Recurrent noncoding U1 snRNA mutations drive cryptic splicing in SHH medulloblastoma. (2019)
• Sequence, Structure, and Context Preferences of Human RNA Binding Proteins. (2018)
• PASSPORT-seq: A Novel High-Throughput Bioassay to Functionally Test Polymorphisms in Micro-RNA Target Sites. (2018)
• Failed Progenitor Specification Underlies the Cardiopharyngeal Phenotypes in a Zebrafish Model of 22q11.2 Deletion Syndrome. (2018)
• ChimeRScope: a novel alignment-free algorithm for fusion transcript prediction using paired-end RNA-Seq data. (2017)
• Assembly of functionally integrated human forebrain spheroids. (2017)
• Integrated analysis of gene expression and copy number identified potential cancer driver genes with amplification-dependent overexpression in 1,454 solid tumors. (2017)
• A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles. (2017)
• Preaxial polydactyly following early gestational exposure to the smoothened agonist, SAG, in C57BL/6J mice. (2017)
• Alternative Polyadenylation Directs Tissue-Specific miRNA Targeting in Somatic Tissues. (2017)
• A practical guide to single-cell RNA-sequencing for biomedical research and clinical applications. (2017)
• Interaction of glycosphingolipids GD3 and GD2 with growth factor receptors maintains breast cancer stem cell phenotype. (2017)
• PGBD5 promotes site-specific oncogenic mutations in human tumors. (2017)
• The Ensembl gene annotation system. (2016)
• Alteration of Gene Expression, DNA Methylation, and Histone Methylation in Free Radical Scavenging Networks in Adult Mouse Hippocampus following Fetal Alcohol Exposure. (2016)
• CEL-Seq2: sensitive highly-multiplexed single-cell RNA-Seq. (2016)
• Rapid Ngn2-induction of excitatory neurons from hiPSC-derived neural progenitor cells. (2016)
• Three decades of nanopore sequencing. (2016)
• Integrative clinical genomics of advanced prostate cancer. (2015)
• Spatial reconstruction of single-cell gene expression data. (2015)
• Prenatal arsenic exposure alters the programming of the glucocorticoid signaling system during embryonic development. (2015)
• Design and bioinformatics analysis of genome-wide CLIP experiments. (2015)
• Identification of cytokine-induced modulation of microRNA expression and secretion as measured by a novel microRNA specific qPCR assay. (2015)
• Droplet barcoding for single-cell transcriptomics applied to embryonic stem cells. (2015)
• Position-specific binding of FUS to nascent RNA regulates mRNA length. (2015)
• Reverse genetic screening reveals poor correlation between morpholino-induced and mutant phenotypes in zebrafish. (2015)
• Comprehensive genomic profiles of small cell lung cancer. (2015)
• Gene expression signatures affected by alcohol-induced DNA methylomic deregulation in human embryonic stem cells. (2014)
• High-throughput transcriptome sequencing identifies candidate genetic modifiers of vulnerability to fetal alcohol spectrum disorders. (2014)
• Inhibition of histone H3K9 acetylation by anacardic acid can correct the over-expression of Gata4 in the hearts of fetal mice exposed to alcohol during pregnancy. (2014)
• Modeling hippocampal neurogenesis using human pluripotent stem cells. (2014)
• Comprehensive analysis of the transcriptional landscape of the human FMR1 gene reveals two new long noncoding RNAs differentially expressed in Fragile X syndrome and Fragile X-associated tremor/ataxia syndrome. (2014)
• Long-lasting alterations to DNA methylation and ncRNAs could underlie the effects of fetal alcohol exposure in mice. (2013)
• Gene expression in the human brain: the current state of the study of specificity and spatiotemporal dynamics. (2013)
• Forebrain and hindbrain development in zebrafish is sensitive to ethanol exposure involving agrin, Fgf, and sonic hedgehog function. (2013)
• Alcohol exposure during development: Impact on the epigenome. (2013)
• Cannabinoid receptor 1 signaling in embryo neurodevelopment. (2012)
• Strain dependent gene expression and neurochemical levels in the brain of zebrafish: focus on a few alcohol related targets. (2012)
• The majority of microRNAs detectable in serum and saliva is concentrated in exosomes. (2012)
• Pilot study of iPS-derived neural cells to examine biologic effects of alcohol on human neurons in vitro. (2012)
• The future of DNA sequence archiving. (2012)
• Circular RNAs are the predominant transcript isoform from hundreds of human genes in diverse cell types. (2012)
• GENCODE: the reference human genome annotation for The ENCODE Project. (2012)
• A promoter polymorphism in the Per3 gene is associated with alcohol and stress response. (2012)
• HLA typing from RNA-Seq sequence reads. (2012)
• Quality control parameters on a large dataset of regionally dissected human control brains for whole genome expression studies. (2011)
• Postmortem interval effect on RNA and gene expression in human brain tissue. (2011)
• Effects of ethanol and NAP on cerebellar expression of the neural cell adhesion molecule L1. (2011)
• MicroRNA expression aberration as potential peripheral blood biomarkers for schizophrenia. (2011)
• MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins. (2011)
• Haemolysis during sample preparation alters microRNA content of plasma. (2011)
• Integrative analysis of the melanoma transcriptome. (2010)
• POLYAR, a new computer program for prediction of poly(A) sites in human sequences. (2010)
• Long noncoding RNAs with enhancer-like function in human cells. (2010)
• Fine mapping of calcineurin (PPP3CA) gene reveals novel alternative splicing patterns, association of 5'UTR trinucleotide repeat with addiction vulnerability, and differential isoform expression in Alzheimer's disease. (2010)
• The role of NOX enzymes in ethanol-induced oxidative stress and apoptosis in mouse embryos. (2010)
• The majority of total nuclear-encoded non-ribosomal RNA in a human cell is 'dark matter' un-annotated RNA. (2010)
• Rapid, low-input, low-bias construction of shotgun fragment libraries by high-density in vitro transposition. (2010)
• Effects of moderate drinking during pregnancy on placental gene expression. (2010)
• Conserved role of intragenic DNA methylation in regulating alternative promoters. (2010)
• Arsenic transport by zebrafish aquaglyceroporins. (2009)
• Microarray analyses reveal regional astrocyte heterogeneity with implications for neurofibromatosis type 1 (NF1)-regulated glial proliferation. (2009)
• Prenatal NAP+SAL prevents developmental delay in a mouse model of Down syndrome through effects on N-methyl-D-aspartic acid and gamma-aminobutyric acid receptors. (2009)
• Computation for ChIP-seq and RNA-seq studies. (2009)
• The relationship of 5HTT (SLC6A4) methylation and genotype on mRNA expression and liability to major depression and alcohol dependence in subjects from the Iowa Adoption Studies. (2008)
• Development and tissue origins of the mammalian cranial base. (2008)
• Identification of novel bone-specific molecular targets of binge alcohol and ibandronate by transcriptome analysis. (2008)
• RNA-seq: an assessment of technical reproducibility and comparison with gene expression arrays. (2008)
• Molecular specification and patterning of progenitor cells in the lateral and medial ganglionic eminences. (2008)
• Fetal alcohol spectrum disorder-associated depression: evidence for reductions in the levels of brain-derived neurotrophic factor in a mouse model. (2008)
• Neuroadaptations in human chronic alcoholics: dysregulation of the NF-kappaB system. (2007)
• A large-scale analysis of mRNA polyadenylation of human and mouse genes. (2005)
• Reciprocal relationships between Fgf8 and neural crest cells in facial and forebrain development. (2004)
• Estrogen inhibits GH signaling by suppressing GH-induced JAK2 phosphorylation, an effect mediated by SOCS-2. (2003)
• Mouse Af9 is a controller of embryo patterning, like Mll, whose human homologue fuses with Af9 after chromosomal translocation in leukemia. (2002)
• A new mathematical model for relative quantification in real-time RT-PCR. (2001)

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