ADH gene
Evidence from:
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Related entities (26)
| Subject | Relation | Object | p-value | Evidence |
|---|---|---|---|---|
| ADH | causes | acetaldehyde | — | 1 |
| ADH | regulates | acetaldehyde | — | 1 |
| ADH | interacts_with | acetaldehyde | — | 3 |
| ADH | regulates | acetic acid | — | 1 |
| ADH | risk_factor_for | addiction | — | 1 |
| ADH | associated_with | alcohol | — | 2 |
| ADH | targets | alcohol | — | 2 |
| ADH | protective_against | alcohol dependence | — | 1 |
| ADH | risk_factor_for | alcoholic liver disease | — | 1 |
| ADH | biomarker_for | alcoholism | — | 1 |
| ADH | risk_factor_for | alcoholism | — | 2 |
| ADH | associated_with | alcohol metabolism | — | 1 |
| ADH | associated_with | alcohol sensitivity | — | 1 |
| ADH | risk_factor_for | Alzheimer's disease | — | 1 |
| ADH | risk_factor_for | AP | — | 1 |
| ADH | interacts_with | ethanol group | — | 4 |
| ADH | targets | ethanol group | — | 2 |
| ADH | risk_factor_for | Liver cirrhosis | — | 1 |
| ADH | regulates | NADH | — | 1 |
| ADH | regulates | retinoic acid | — | 1 |
| ADH | associated_with | rs1229984 | — | 1 |
| ADH | associated_with | rs698 | — | 1 |
| ADH | risk_factor_for | tobacco dependence | — | 1 |
| ALDH2 | interacts_with | ADH | — | 1 |
| ethanol group | interacts_with | ADH | — | 1 |
| NADH | associated_with | ADH | — | 1 |
Mentioned in (50)
Papers in which this entity is mentioned.
- Pathogenesis of Alcoholic Fatty Liver a Narrative Review. (2023)
- Gene-alcohol interactions in birth defects. (2023)
- The Promise and Peril of Genetics. (2022)
- Beneficial Effects of Betaine: A Comprehensive Review. (2021)
- Murine Models for the Study of Fetal Alcohol Spectrum Disorders: An Overview. (2020)
- Effects of prenatal alcohol exposure (PAE): insights into FASD using mouse models of PAE. (2018)
- Alcohol and the Brain: Neuronal Molecular Targets, Synapses, and Circuits. (2017)
- Ethanol itself is a holoprosencephaly-inducing teratogen. (2017)
- Disconnect between alcohol-induced alterations in chromatin structure and gene transcription in a mouse embryonic stem cell model of exposure. (2017)
- Lipids and Oxidative Stress Associated with Ethanol-Induced Neurological Damage. (2016)
- The Genetics of Fetal Alcohol Spectrum Disorders. (2016)
- Dose-dependent alcohol-induced alterations in chromatin structure persist beyond the window of exposure and correlate with fetal alcohol syndrome birth defects. (2015)
- Zebrafish retinal defects induced by ethanol exposure are rescued by retinoic acid and folic acid supplement. (2015)
- Genomic influences on alcohol problems in a population-based sample of young adults. (2015)
- Clinically relevant genetic biomarkers from the brain in alcoholism with representation on high resolution chromosome ideograms. (2015)
- Importance of genetics in fetal alcohol effects: null mutation of the nNOS gene worsens alcohol-induced cerebellar neuronal losses and behavioral deficits. (2015)
- Evaluation of the influence of alcohol dehydrogenase polymorphisms on alcohol elimination rates in African Americans. (2014)
- Genomic factors that shape craniofacial outcome and neural crest vulnerability in FASD. (2014)
- Gene-ethanol interactions underlying fetal alcohol spectrum disorders. (2014)
- Using genetic information from candidate gene and genome-wide association studies in risk prediction for alcohol dependence. (2014)
- Polygenic risk scores for smoking: predictors for alcohol and cannabis use? (2014)
- Renal dysfunction in fetal alcohol syndrome: a potential contributor on developmental disabilities of offspring. (2014)
- Prenatal alcohol exposure and offspring cognition and school performance. A 'Mendelian randomization' natural experiment. (2013)
- Alcohol metabolism and epigenetics changes. (2013)
- Common liability to addiction and "gateway hypothesis": theoretical, empirical and evolutionary perspective. (2012)
- The genetics of alcohol dependence: advancing towards systems-based approaches. (2012)
- Ethanol metabolism and osmolarity modify behavioral responses to ethanol in C. elegans. (2012)
- The genetic basis of alcoholism: multiple phenotypes, many genes, complex networks. (2012)
- The genetic basis of addictive disorders. (2012)
- Gene expression changes in C57BL/6J and DBA/2J mice following prenatal alcohol exposure. (2012)
- A Drosophila model for fetal alcohol syndrome disorders: role for the insulin pathway. (2011)
- A genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortium. (2011)
- Strain differences in developmental vulnerability to alcohol exposure via embryo culture in mice. (2011)
- The investigation into CYP2E1 in relation to the level of response to alcohol through a combination of linkage and association analysis. (2011)
- Effects of ethanol on physiological retinoic acid levels. (2011)
- Genetic and epigenetic insights into fetal alcohol spectrum disorders. (2010)
- Ethanol teratogenesis in five inbred strains of mice. (2009)
- Dense genomewide linkage scan for alcohol dependence in African Americans: significant linkage on chromosome 10. (2009)
- Peroxisome proliferator-activated receptor and retinoic x receptor in alcoholic liver disease. (2009)
- Genome-wide association study of alcohol dependence. (2009)
- Alcohol consumption indices of genetic risk for alcohol dependence. (2009)
- Alterations in ethyl alcohol pharmacokinetics during oral consumption of malt liquor beverages in African Americans. (2008)
- Ethanol's molecular targets. (2008)
- Mechanism of alcohol-induced oxidative stress and neuronal injury. (2008)
- Variations in alcohol-metabolizing enzymes in people of East Indian and African descent from Trinidad and Tobago. (2007)
- Distinct methylation patterns in histone H3 at Lys-4 and Lys-9 correlate with up- & down-regulation of genes by ethanol in hepatocytes. (2007)
- The genetics of alcohol metabolism: role of alcohol dehydrogenase and aldehyde dehydrogenase variants. (2007)
- The genetics of alcohol metabolism: role of alcohol dehydrogenase and aldehyde dehydrogenase variants. (2007)
- Co-occurring risk factors for alcohol dependence and habitual smoking: update on findings from the Collaborative Study on the Genetics of Alcoholism. (2006)
- Modeling alcohol's effects on organs in animal models. (2000)
Merged raw entities (4)
All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.
| Raw name | Type | Papers | Mentions |
|---|---|---|---|
| adh | gene | 50 | 113 |
| adh gene | gene | 1 | 1 |
| adhs | gene | — | — |
| cytosolic alcohol dehydrogenase | gene | — | — |