alcohol risk_factor_for alcohol dependence
Evidence from:
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all sources
Evidence (32 sources)
Genome-wide association study of nicotine dependence in American populations: identification of novel risk loci in both African-Americans and European-Americans.
(2015)
PMID:25555482
primary
studies of the genetics of drug (opioid or cocaine) or alcohol dependence
confidence: 0.90
A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53.
(2013)
PMID:23089632
primary
individuals ... who had reported ever consuming alcohol.
confidence: 0.80
A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.
(2013)
PMID:23743675
primary
Consumption of alcohol in large quantities ... is associated with increased risk of alcohol dependence ...
confidence: 0.96
A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53.
(2013)
PMID:23089632
primary
alcohol consumption ... are highly correlated with alcohol dependence and index closely the risk for alcohol dependence
confidence: 0.95
A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53.
(2013)
PMID:23089632
primary
GWAS using quantitative traits derived from alcohol consumption ... for AD
confidence: 0.60
Genome-wide association study of theta band event-related oscillations identifies serotonin receptor gene HTR7 influencing risk of alcohol dependence.
(2011)
PMID:21184583
primary
alcohol dependent subjects ... indicates dependence on alcohol
confidence: 0.90
Long-term effects of minimum drinking age laws on past-year alcohol and drug use disorders.
(2009)
PMID:19775322
primary
nearly identical for ... alcohol dependence (1.27, 95% c.i. 1.11 to 1.45, p = .001) when these diagnoses were considered separately
confidence: 0.90
Co-occurring risk factors for alcohol dependence and habitual smoking: update on findings from the Collaborative Study on the Genetics of Alcoholism.
(2006)
PMID:17373405
primary
genes that contribute to the risk of alcohol dependence
confidence: 0.80
The neural correlates of the unified percept of alcohol-related craving: a fMRI and EEG study.
(2018)
PMID:29343732
cited
excessive consumption of the substance... results in... an addicted state
confidence: 0.95
The neural correlates of the unified percept of alcohol-related craving: a fMRI and EEG study.
(2018)
PMID:29343732
cited
Excessive consumption of alcohol leads to alcohol dependence...
confidence: 0.96
Genetic studies of alcohol dependence in the context of the addiction cycle.
(2017)
PMID:28118990
cited
well described role of genetic variation in the alcohol metabolizing genes and risk for alcohol dependence.
confidence: 0.70
Genetic studies of alcohol dependence in the context of the addiction cycle.
(2017)
PMID:28118990
cited
Heath et al., 2011 performed a GWAS of alcohol dependence using several quantitative phenotypes
confidence: 0.85
Alcohol Dependence Genetics: Lessons Learned From Genome-Wide Association Studies (GWAS) and Post-GWAS Analyses.
(2015)
PMID:26110981
cited
characterized by the excessive and compulsive use of alcohol
confidence: 0.95
We searched in PubMed and reviewed 45 GWASs of alcohol dependence (i.e., “alcoholism”, “alcohol dependence” and “alcohol addiction”).
confidence: 0.60
Prevalence of DSM-IV and DSM-5 alcohol, cocaine, opioid, and cannabis use disorders in a largely substance dependent sample.
(2013)
PMID:22884164
cited
presence of a ... alcohol dependence diagnosis
confidence: 0.90
exposure to alcohol is a necessary condition for the eventual development of alcohol-related problems.
confidence: 0.90
The genetics of alcohol dependence: advancing towards systems-based approaches.
(2012)
PMID:22854292
cited
vulnerability to AD ... disrupted by alcohol ...
confidence: 0.90
The genetics of alcohol dependence: advancing towards systems-based approaches.
(2012)
PMID:22854292
cited
people become addicted or remain addicted to alcohol
confidence: 0.90
The genetics of alcohol dependence: advancing towards systems-based approaches.
(2012)
PMID:22854292
cited
individuals who consume large amounts of alcohol ... are likely to demonstrate ... a diagnosis of dependence
confidence: 0.92
The genetics of alcohol dependence: advancing towards systems-based approaches.
(2012)
PMID:22854292
cited
children that were prenatally exposed to alcohol ... the risk for AD is elevated
confidence: 0.95
Theta oscillations are sensitive to both early and late conflict processing stages: effects of alcohol intoxication.
(2012)
PMID:22952823
cited
alcohol… may contribute to alcohol dependence
confidence: 0.90
Pilot study of iPS-derived neural cells to examine biologic effects of alcohol on human neurons in vitro.
(2012)
PMID:22486492
cited
environmental effect of chronic alcohol exposure in AD donor subjects
confidence: 0.75
Environmental influences predominate in remission from alcohol use disorder in young adult twins.
(2012)
PMID:22423619
cited
Data on alcohol dependence symptoms were used in this analysis
confidence: 0.60
Adolescent binge drinking alters adult brain neurotransmitter gene expression, behavior, brain regional volumes, and neurochemistry in mice.
(2011)
PMID:21223304
cited
The lifetime prevalence of past‑year alcohol dependence peaks at 12% between the ages of 18 and 20
confidence: 0.91
changes in gene expression in response to alcohol ... responsible for ... alcohol dependence
confidence: 0.94
The relationship between genetic influences on alcohol dependence and on patterns of alcohol consumption.
(2010)
PMID:20374207
cited
measures of the frequency and quantity of AC reflect the genetic risk for AD
confidence: 0.95
The relationship between genetic influences on alcohol dependence and on patterns of alcohol consumption.
(2010)
PMID:20374207
cited
measures for AC may capture most ... genetic influences on AC include factors unrelated to AD
confidence: 0.70
Common genetic contributions to alcohol and cannabis use and dependence symptomatology.
(2010)
PMID:20028363
cited
evidence suggests there is a dose-response effect between levels of consumption and risk of dependence.
confidence: 0.95
Common genetic contributions to alcohol and cannabis use and dependence symptomatology.
(2010)
PMID:20028363
cited
rates of AD in women increased dramatically from the 60th to 80th percentile and from the 80th percentile to the highest consumption levels; prevalence in heaviest drinking females was higher than in heaviest drinking males
confidence: 0.95
Timing of first alcohol use and alcohol dependence: evidence of common genetic influences.
(2009)
PMID:19686520
cited
association between age at initiation of alcohol use and risk for AD was consistent across sexes
confidence: 0.85
continuous measures such as consumption are considerably more powerful predictors ... contribute to AD risk
confidence: 0.85
Neuroadaptations in human chronic alcoholics: dysregulation of the NF-kappaB system.
(2007)
PMID:17895971
cited
alcohol dependence ... result from neuroadaptations to chronic alcohol consumption
confidence: 0.90