CB1 receptor regulates GABA

Subject: CB1 receptor
Relation: regulates
Object: GABA
p-value: —

Evidence from: primary | all sources

Evidence (3 sources)

Cortical glutamic acid decarboxylase 67 deficiency results in lower cannabinoid 1 receptor messenger RNA expression: implications for schizophrenia. (2012) PMID:22036037 cited

CB1R activation suppresses GABA neurotransmission

confidence: 0.95

Cannabis and psychosis/schizophrenia: human studies. (2009) PMID:19609589 cited

By suppressing GABAergic ... CB1R activation might lead to non-specific activation of the PFC.

confidence: 0.85

Hippocampal CB(1) receptors mediate the memory impairing effects of Delta(9)-tetrahydrocannabinol. (2009) PMID:19322169 cited

Activation of hippocampal CB1 receptors decreases GABA release.

confidence: 0.97