SNP associated_with trait

h_{SNP,i}^2 being the SNP-heritability of the trait analyzed in GWAS i

enrichment analysis is moving ... when studying associations with traits.

Z_GWAS is the Z-score of the association between SNP and trait

average 50% increase in eligible SNP-trait associations year on year

To simulate trait data yi* for individual i ... at a single SNP, we used the following model: yi* = μ* + (−a)I{gi=0} + (d)I{gi=1} + (a)I{gi=2} + εi

examining associations between SNP genotype frequency and traits

GWAS have identified hundreds of loci associated with ... traits.

SNPs are genotyped and (individually) tested for association with a trait or disorder.

each SNP that survives quality control and cleaning is then tested for association with a disease or trait.

testing a direct association between the polymorphism and the trait rather than relying on indirect association