LocusZoom: regional visualization of genome-wide association scan results.
paper
Cited
Public
- Authors
- Pruim, Randall J; Welch, Ryan P; Sanna, Serena; Teslovich, Tanya M; Chines, Peter S; Gliedt, Terry P; Boehnke, Michael; Abecasis, Gonçalo R; Willer, Cristen J
- Year
- 2010
- Journal
- Bioinformatics (Oxford, England)
- PMID
- 20634204
- DOI
- 10.1093/bioinformatics/btq419
- PMCID
- PMC2935401
UNLABELLED: Genome-wide association studies (GWAS) have revealed hundreds of loci associated with common human genetic diseases and traits. We have developed a web-based plotting tool that provides fast visual display of GWAS results in a publication-ready format. LocusZoom visually displays regional information such as the strength and extent of the association signal relative to genomic position, local linkage disequilibrium (LD) and recombination patterns and the positions of genes in the region. AVAILABILITY: LocusZoom can be accessed from a web interface at http://csg.sph.umich.edu/locuszoom. Users may generate a single plot using a web form, or many plots using batch mode. The software utilizes LD information from HapMap Phase II (CEU, YRI and JPT+CHB) or 1000 Genomes (CEU) and gene information from the UCSC browser, and will accept SNP identifiers in dbSNP or 1000 Genomes format. Single plots are generated in approximately 20 s. Source code and associated databases are available for download and local installation, and full documentation is available online.
An example LocusZoom plot showing the HDL cholesterol-associated region near the MMAB gene (Kathiresan et al., 2009).
1β11 of 11
| Name | Type |
|---|---|
| 1000 Genomes Project | cohort |
| CEU | cohort |
| CHB | cohort |
| coding_variant local | variant |
| complex diseases | phenotype |
| dbSNP | cohort |
| European ancestry | cohort |
| HapMap | cohort |
| HDL cholesterol | phenotype |
| index SNP | cohort |
| JPT | cohort |
| Kathiresan et al., 2009 local | cohort |
| LDL cholesterol | phenotype |
| LocusZoom local | drug |
| multi_species_conservation local | variant |
| nonsense_variant local | variant |
| non_synonymous_variant local | variant |
| novel SNPs local | variant |
| sequencing studies local | cohort |
| SNP | cohort |
| splice_variant local | variant |
| strongly associated variants local | variant |
| trait | phenotype |
| transcription_factor_binding_site local | variant |
| triglycerides | phenotype |
| UTR_variant local | variant |
| YRI | cohort |
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| Genetic risk for hospitalization of African American patients with severe mental illness reveals HLA loci. | Lori A et al. | β | 2024 | β |
| Genetic variants for head size share genes and pathways with cancer. | Knol MJ et al. | β | 2024 | β |
| Genetic variants of <i>LRRC8C</i>, <i>OAS2</i>, and <i>CCL25</i> in the T cell exhaustion-related genes are associated with non-small cell lung cancer survival. | Lu G et al. | β | 2024 | β |
| Genome-wide analyses of neonatal jaundice reveal a marked departure from adult bilirubin metabolism. | SolΓ©-Navais P et al. | β | 2024 | β |
| Genome-wide association analyses identify 95 risk loci and provide insights into the neurobiology of post-traumatic stress disorder. | Nievergelt CM et al. | β | 2024 | β |
| Genome-wide association analyses of breast cancer in women of African ancestry identify new susceptibility loci and improve risk prediction. | Jia G et al. | β | 2024 | β |
| Genome-wide association and Mendelian randomisation analysis among 30,699 Chinese pregnant women identifies novel genetic and molecular risk factors for gestational diabetes and glycaemic traits. | Zhen J et al. | β | 2024 | β |
| Genome-wide association reveals a locus in neuregulin 3 associated with gabapentin efficacy in women with chronic pelvic pain. | Mackenzie SC et al. | β | 2024 | β |
| Genome-wide association studies for pelvic organ prolapse in the Japanese population. | Matsunami M et al. | β | 2024 | β |
| Genome-wide association studies highlight novel risk loci for septal defects and left-sided congenital heart defects. | Broberg M et al. | β | 2024 | β |
| Genome-wide association study and meta-analysis of phytosterols identifies a novel locus for serum levels of campesterol. | Alenbawi J et al. | β | 2024 | β |
| Genome-Wide Association Study and Meta-Analysis of Phytosterols Identifies a Novel Locus for Serum Levels of Campesterol | Alenbawi J et al. | β | 2024 | β |
| Genome-wide association study and trans-ethnic meta-analysis identify novel susceptibility loci for type 2 diabetes mellitus. | Elashi AA et al. | β | 2024 | β |
| Genome-wide association study for metabolic syndrome reveals APOA5 single nucleotide polymorphisms with multilayered effects in Koreans. | Park YJ et al. | β | 2024 | β |
| Genome-Wide Association Study Identifies IFIH1 and HLA-DQB1*05:02 Loci Associated With Anti-NMDAR Encephalitis. | Liu X et al. | β | 2024 | β |
| Genome-wide association study implicates the role of TBXAS1 in the pathogenesis of depressive symptoms among the Korean population. | Park K et al. | β | 2024 | β |
| Genome-wide association study meta-analysis of neurofilament light (NfL) levels in blood reveals novel loci related to neurodegeneration. | Ahmad S et al. | β | 2024 | β |
| Genome-wide association study of maternal plasma metabolites during pregnancy. | Liu S et al. | β | 2024 | β |
| Genome-wide association study of metabolic dysfunction-associated fatty liver disease in a Korean population. | Lee Y et al. | β | 2024 | β |
| Genome-wide association study of nausea and vomiting during pregnancy in Japan: the TMM BirThree Cohort Study. | Yonezawa Y et al. | β | 2024 | β |
| Genome-wide Association Study of Susceptibility Loci for Self-Reported Atopic Dermatitis and Allergic Rhinitis in the Korean Population. | Kim JW et al. | β | 2024 | β |
| Genome-wide association study of susceptibility to <i>Pseudomonas aeruginosa</i> infection in cystic fibrosis. | Lin B et al. | β | 2024 | β |
| Genome-wide association study of traumatic brain injury in U.S. military veterans enrolled in the VA million veteran program. | Merritt VC et al. | β | 2024 | β |
| Genome-Wide Association Study to Identify Genetic Factors Linked to HBV Reactivation Following Liver Transplantation in HBV-Infected Patients. | Park J et al. | β | 2024 | β |
| Genome-Wide Association Study with Three Control Cohorts of Japanese Patients with Esotropia and Exotropia of Comitant Strabismus and Idiopathic Superior Oblique Muscle Palsy. | Matsuo T et al. | β | 2024 | β |
| Genome-wide interaction study of dietary intake of fibre, fruits, and vegetables with risk of colorectal cancer. | Papadimitriou N et al. | β | 2024 | β |
| Gout-associated SNP at the IL1RN-IL1F10 region is associated with altered cytokine production in PBMCs of patients with gout and controls. | Gaal OI et al. | β | 2024 | β |
| GWAS for systemic sclerosis identifies six novel susceptibility loci including one in the FcΞ³ receptor region. | Ishikawa Y et al. | β | 2024 | β |
| GWAS of multiple neuropathology endophenotypes identifies new risk loci and provides insights into the genetic risk of dementia. | Shade LMP et al. | β | 2024 | β |
| Higher oxygen content and transport characterize high-altitude ethnic Tibetan women with the highest lifetime reproductive success. | Ye S et al. | β | 2024 | β |
| High incidence and geographic distribution of cleft palate in Finland are associated with the IRF6 gene. | Rahimov F et al. | β | 2024 | β |
| Identification of genetic variants associated with clinical features of sickle cell disease. | Tsukahara K et al. | β | 2024 | β |
| Identification of the VLDLR locus associated with giant cell arteritis and the possible causal role of low-density lipoprotein cholesterol in its pathogenesis. | Iwasaki T et al. | β | 2024 | β |
| Implication of transcription factor FOXD2 dysfunction in syndromic congenital anomalies of the kidney and urinary tract (CAKUT). | Riedhammer KM et al. | β | 2024 | β |
| Instrumental variable and colocalization analyses identify endotrophin and HTRA1 as potential therapeutic targets for coronary artery disease. | Lee PC et al. | β | 2024 | β |
| Integrating genetic regulation and single-cell expression with GWAS prioritizes causal genes and cell types for glaucoma. | Hamel AR et al. | β | 2024 | β |
| Integrating multi-omics data to reveal the effect of genetic variant rs6430538 on Alzheimer's disease risk. | Qiu S et al. | β | 2024 | β |
| Lack of genetic evidence for NLRP3 inflammasome involvement in Parkinson's disease pathogenesis. | Senkevich K et al. | β | 2024 | β |
| Large-scale cross-ancestry genome-wide meta-analysis of serum urate. | Cho C et al. | β | 2024 | β |
| LINC02257 regulates malignant phenotypes of colorectal cancer via interacting with miR-1273g-3p and YB1. | Park MS et al. | β | 2024 | β |
| Liver eQTL meta-analysis illuminates potential molecular mechanisms of cardiometabolic traits. | Broadaway KA et al. | β | 2024 | β |
| Loci on chromosome 20 interact with rs16969968 to influence cigarettes per day in European ancestry individuals. | Romero Villela PN et al. | β | 2024 | β |
| Mendelian randomization and colocalization analysis reveal novel drug targets for myasthenia gravis. | Ouyang Y et al. | β | 2024 | β |
| Meta-Analysis of Genome-Wide Association Studies Reveals Genetic Mechanisms of Supraventricular Arrhythmias. | Weng LC et al. | β | 2024 | β |
| Multiomic integration analysis identifies atherogenic metabolites mediating between novel immune genes and cardiovascular risk. | Carreras-Torres R et al. | β | 2024 | β |
| NEK4 modulates circadian fluctuations of emotional behaviors and synaptogenesis in male mice. | Yang ZH et al. | β | 2024 | β |
| Neuroimaging genomics as a window into the evolution of human sulcal organization. | Goltermann O et al. | β | 2024 | β |
| New genetic biomarkers predicting 5-aminosalicylate-induced adverse events in patients with inflammatory bowel diseases. | Park J et al. | β | 2024 | β |
| New insights into the hypothalamic-pituitary-thyroid axis: a transcriptome- and proteome-wide association study. | Monteiro-Martins S et al. | β | 2024 | β |
| NIAGADS Alzheimer's GenomicsDB: A resource for exploring Alzheimer's disease genetic and genomic knowledge. | Greenfest-Allen E et al. | β | 2024 | β |
| Non-targeted metabolomics revealed novel links between serum metabolites and primary ovarian insufficiency: a Mendelian randomization study. | Chen S et al. | β | 2024 | β |
| Novel genetic insight for psoriasis: integrative genome-wide analyses in 863Β 080 individuals and proteome-wide Mendelian randomization. | Liu S et al. | β | 2024 | β |
| Pharmacogenomics of clinical response to Natalizumab in multiple sclerosis: a genome-wide multi-centric association study. | Clarelli F et al. | β | 2024 | β |
| Potentially functional genetic variants in ferroptosis-related CREB3 and GALNT14 genes predict survival of hepatitis B virus-related hepatocellular carcinoma. | Zhan S et al. | β | 2024 | β |
| Primary osteoarthritis chondrocyte map of chromatin conformation reveals novel candidate effector genes. | Bittner N et al. | β | 2024 | β |
| Proteo-genomics of soluble TREM2 in cerebrospinal fluid provides novel insights and identifies novel modulators for Alzheimer's disease. | Wang L et al. | β | 2024 | β |
| Rare variants at KCNJ2 are associated with LDL-cholesterol levels in a cross-population study. | Rossi N et al. | β | 2024 | β |
| Reduction of APOE accounts for neurobehavioral deficits in fetal alcohol spectrum disorders. | Hwang HM et al. | β | 2024 | β |
| Regression convolutional neural network models implicate peripheral immune regulatory variants in the predisposition to Alzheimer's disease. | Ramamurthy E et al. | β | 2024 | β |
| Regulatory elements in <i>SEM1-DLX5-DLX6</i> (7q21.3) locus contribute to genetic control of coronal nonsyndromic craniosynostosis and bone density-related traits. | Nicoletti P et al. | β | 2024 | β |
| Rome III Criteria Capture Higher Irritable Bowel Syndrome SNP-Heritability and Highlight a Novel Genetic Link With Cardiovascular Traits. | Camargo Tavares L et al. | β | 2024 | β |
| RPTOR Is an Alzheimer's Disease Susceptibility Gene Associated with the Risk Factors Body Mass Index and Infectious Encephalitis. | Lehrer S et al. | β | 2024 | β |
| Sex-specific genetic architecture of blood pressure. | Yang ML et al. | β | 2024 | β |
| Single-Cell Transcriptomic and Targeted Genomic Profiling Adjusted for Inflammation and Therapy Bias Reveal <i>CRTAM</i> and <i>PLCB1</i> as Novel Hub Genes for Anti-Tumor Necrosis Factor Alpha Therapy Response in Crohn's Disease. | Gorenjak M et al. | β | 2024 | β |
| Spatial, transcriptomic, and epigenomic analyses link dorsal horn neurons to chronic pain genetic predisposition. | Arokiaraj CM et al. | β | 2024 | β |
| SpRY-mediated screens facilitate functional dissection of non-coding sequences at single-base resolution. | Yao Y et al. | β | 2024 | β |
| The Born in Guangzhou Cohort Study enables generational genetic discoveries. | Huang S et al. | β | 2024 | β |
| The genetic landscape of neuro-related proteins in human plasma. | Repetto L et al. | β | 2024 | β |
| The Human Genetic Differences in the Outcomes of mRNA Vaccination against COVID-19: A Prospective Cohort Study. | Ryu HE et al. | β | 2024 | β |
| TOPMed imputed genomics enhances genomic atlas of the human proteome in brain, cerebrospinal fluid, and plasma. | Yi H et al. | β | 2024 | β |
| Two genome-wide interaction loci modify the association of nonsteroidal anti-inflammatory drugs with colorectal cancer. | Drew DA et al. | β | 2024 | β |
| Using genetics to investigate the association between lanosterol and cataract. | Hashimi M et al. | β | 2024 | β |
| Whole-genome sequencing identifies variants in ANK1, LRRN1, HAS1, and other genes and regulatory regions for stroke in type 1 diabetes. | Antikainen AA et al. | β | 2024 | β |
| Whole-genome sequencing in 333,100 individuals reveals rare non-coding single variant and aggregate associations with height. | Hawkes G et al. | β | 2024 | β |
| Whole genome-wide sequence analysis of long-lived families (Long-Life Family Study) identifies MTUS2 gene associated with late-onset Alzheimer's disease. | Xicota L et al. | β | 2024 | β |
| 150 risk variants for diverticular disease of intestine prioritize cell types and enable polygenic prediction of disease susceptibility. | Wu Y et al. | β | 2023 | β |
| A 21-bp InDel in the promoter of <i>STP1</i> selected during tomato improvement accounts for soluble solid content in fruits. | Wang Y et al. | β | 2023 | β |
| A Genetic Locus within the FMN1/GREM1 Gene Region Interacts with Body Mass Index in Colorectal Cancer Risk. | Aglago EK et al. | β | 2023 | β |
| A genome-wide association study for allergen component sensitizations identifies allergen component-specific and allergen protein group-specific associations. | Morii W et al. | β | 2023 | β |
| A genome-wide association study (GWAS) of the personality constructs in CPAI-2 in Taiwanese Hakka populations. | Kao PY et al. | β | 2023 | β |
| A genome-wide association study of blood cell morphology identifies cellular proteins implicated in disease aetiology. | Akbari P et al. | β | 2023 | β |
| A Guide to Genome-Wide Association Study Design for Diabetic Retinopathy. | Gurung RL et al. | β | 2023 | β |
| A meta-analysis of genome-wide association studies of childhood wheezing phenotypes identifies <i>ANXA1</i> as a susceptibility locus for persistent wheezing. | Granell R et al. | β | 2023 | β |
| A multiethnic genome-wide analysis of 19,420 individuals identifies novel loci associated with axial length and shared genetic influences with refractive error and myopia. | Jiang C et al. | β | 2023 | β |
| A multivariate genome-wide association study of psycho-cardiometabolic multimorbidity. | Baltramonaityte V et al. | β | 2023 | β |
| Analysis of gut microbiome, host genetics, and plasma metabolites reveals gut microbiome-host interactions in the Japanese population. | Tomofuji Y et al. | β | 2023 | β |
| A Polynesian<i>-</i>specific missense CETP variant alters the lipid profile. | Moors J et al. | β | 2023 | β |
| A regulatory variant at 19p13.3 is associated with primary biliary cholangitis risk and ARID3A expression. | Li Y et al. | β | 2023 | β |
| A shared genetic architecture between adhesive capsulitis and Dupuytren disease. | Kim SK et al. | β | 2023 | β |
| Assessing efficiency of fine-mapping obesity-associated variants through leveraging ancestry architecture and functional annotation using PAGE and UKBB cohorts. | Anwar MY et al. | β | 2023 | β |
| Assessing the associations between known genetic variants and substance use in people with HIV in the United States. | Haas CB et al. | β | 2023 | β |
| Association between birth by caesarian section and anxiety, self-harm: a gene-environment interaction study using UK Biobank data. | Jia Y et al. | β | 2023 | β |
| Association of PDGFRA polymorphisms with the risk of corneal astigmatism in a Japanese population. | Fukasaku H et al. | β | 2023 | β |
| Associations between the New DNA-Methylation-Based Telomere Length Estimator, the Mediterranean Diet and Genetics in a Spanish Population at High Cardiovascular Risk. | Coltell O et al. | β | 2023 | β |
| Atopic Polygenic Risk Score Is Associated with Paradoxical Eczema Developing in Patients with Psoriasis Treated with Biologics. | Al-Janabi A et al. | β | 2023 | β |
| A two-stage genome-wide association study identifies novel germline genetic variations in CACNA2D3 associated with radiotherapy response in nasopharyngeal carcinoma. | Yu LL et al. | β | 2023 | β |
| Bicuspid Aortic Valve-Associated Regulatory Regions Reveal <i>GATA4</i> Regulation and Function During Human-Induced Pluripotent Stem Cell-Based Endothelial-Mesenchymal Transition-Brief Report. | Huang T et al. | β | 2023 | β |
| Biliary atresia is associated with polygenic susceptibility in ciliogenesis and planar polarity effector genes. | Glessner JT et al. | β | 2023 | β |
| Candidate pathway analysis of surfactant proteins identifies CTSH and SFTA2 that influences lung cancer risk. | Luyapan J et al. | β | 2023 | β |
| Causal associations and genetic overlap between COVID-19 and intelligence. | Cao H et al. | β | 2023 | β |
| Causal associations and shared genetics between hypertension and COVID-19. | Baranova A et al. | β | 2023 | β |
| Causal genetic regulation of DNA replication on immune microenvironment in colorectal tumorigenesis: Evidenced by an integrated approach of trans-omics and GWAS. | Wang S et al. | β | 2023 | β |
| Cell-Type Composition Affects Adipose Gene Expression Associations With Cardiometabolic Traits. | Brotman SM et al. | β | 2023 | β |
| Colocalization of expression transcripts with COVID-19 outcomes is rare across cell states, cell types and organs. | Willett JDS et al. | β | 2023 | β |
| Common and ethnic-specific genetic determinants of hemoglobin concentration between Taiwanese Han Chinese and European Whites: findings from comparative two-stage genome-wide association studies. | Timoteo VJ et al. | β | 2023 | β |
| Common Risk Variants in <i>AHI1</i> Are Associated With Childhood Steroid Sensitive Nephrotic Syndrome. | Downie ML et al. | β | 2023 | β |
| Common Variants on <i>FGD5</i> Increase Hazard of Mortality or Rehospitalization in Patients With Heart Failure From the ASCEND-HF Trial. | Gui H et al. | β | 2023 | β |
| Comparing variants related to chronic diseases from genome-wide association study (GWAS) and the cancer genome atlas (TCGA). | Jeon S et al. | β | 2023 | β |
| Comparison of the loci associated with HbA1c and blood glucose levels identified by a genome-wide association study in the Japanese population. | Sakashita T et al. | β | 2023 | β |
| crosshap: R package for local haplotype visualization for trait association analysis. | Marsh JI et al. | β | 2023 | β |
| Cumulative Genetic Score and <i>C9orf72</i> Repeat Status Independently Contribute to Amyotrophic Lateral Sclerosis Risk in 2 Case-Control Studies. | Dou J et al. | β | 2023 | β |
| Differences and commonalities in the genetic architecture of protein quantitative trait loci in European and Arab populations. | Thareja G et al. | β | 2023 | β |
| East Asian-specific and cross-ancestry genome-wide meta-analyses provide mechanistic insights into peptic ulcer disease. | He Y et al. | β | 2023 | β |
| Effect of all-but-one conditional analysis for eQTL isolation in peripheral blood. | Brown M et al. | β | 2023 | β |
| Elevated plasma complement factor H related 5 protein is associated with venous thromboembolism. | Iglesias MJ et al. | β | 2023 | β |
| Ethnicity- and sex-specific genome wide association study on Parkinson's disease. | Park KW et al. | β | 2023 | β |
| Evaluation of SNPs associated with mammographic density in European women with mammographic density in Asian women from South-East Asia. | Mariapun S et al. | β | 2023 | β |
| Functional genomics identify causal variant underlying the protective CTSH locus for Alzheimer's disease. | Li Y et al. | β | 2023 | β |
| Gene burden analysis identifies genes associated with increased risk and severity of adult-onset hearing loss in a diverse hospital-based cohort. | Hui D et al. | β | 2023 | β |
| Genetic Architecture of Ischaemic Strokes after COVID-19 Shows Similarities with Large Vessel Strokes. | LluciΓ -Carol L et al. | β | 2023 | β |
| Genetic architecture of spatial electrical biomarkers for cardiac arrhythmia and relationship with cardiovascular disease. | Young WJ et al. | β | 2023 | β |
| Genetic basis of STEM occupational choice and regional economic performance: a UK biobank genome-wide association study. | Zhu C et al. | β | 2023 | β |
| Genetic contributions to female gout and hyperuricaemia using genome-wide association study and polygenic risk score analyses. | Lin CY et al. | β | 2023 | β |
| Genetic contributions to transdiagnostic symptom dimensions in patients with major depressive disorder, bipolar disorder, and schizophrenia spectrum disorders. | David FS et al. | β | 2023 | β |
| Genetic determinants of Vitamin D deficiency in the Middle Eastern Qatari population: a genome-wide association study. | Hendi NN et al. | β | 2023 | β |
| Genetic factors associated with serum amylase in a Japanese population: combined analysis of copy-number and single-nucleotide variants. | Nayema Z et al. | β | 2023 | β |
| Genetic fine-mapping reveals single nucleotide polymorphism mutations in the MC1R regulatory region associated with duck melanism. | Liu H et al. | β | 2023 | β |
| Genetic insights into ossification of the posterior longitudinal ligament of the spine. | Koike Y et al. | β | 2023 | β |
| Genetic pathways regulating the longitudinal acquisition of cocaine self-administration in a panel of inbred and recombinant inbred mice. | Khan AH et al. | β | 2023 | β |
| Genetic Regulation of SMC Gene Expression and Splicing Predict Causal CAD Genes. | Aherrahrou R et al. | β | 2023 | β |
| GeneticsMakie.jl: a versatile and scalable toolkit for visualizing locus-level genetic and genomic data. | Kim M et al. | β | 2023 | β |
| Genetic studies of paired metabolomes reveal enzymatic and transport processes at the interface of plasma and urine. | Schlosser P et al. | β | 2023 | β |
| Genetic variants in the SHISA6 gene are associated with delayed cognitive impairment in two family datasets. | Ramos J et al. | β | 2023 | β |
| Genetic variation in the human leukocyte antigen region confers susceptibility to Clostridioides difficile infection. | Ferar K et al. | β | 2023 | β |
| Genome-Wide Analysis of Left Ventricular Maximum Wall Thickness in the UK Biobank Cohort Reveals a Shared Genetic Background With Hypertrophic Cardiomyopathy. | Aung N et al. | β | 2023 | β |
| Genome-wide Analysis of Motor Progression in Parkinson Disease. | MartΓnez Carrasco A et al. | β | 2023 | β |
| Genome-wide assessment reveals a significant association between ACSS3 and physical activity. | Jo J et al. | β | 2023 | β |
| Genome-wide association analyses identified novel susceptibility loci for pulmonary embolism among Han Chinese population. | Zhang Z et al. | β | 2023 | β |
| Genome-wide association analysis identifies ancestry-specific genetic variation associated with acute response to metformin and glipizide in SUGAR-MGH. | Li JH et al. | β | 2023 | β |
| Genome-Wide Association Analysis of Protein-Coding Variants in IgA Nephropathy. | Li M et al. | β | 2023 | β |
| Genome-Wide Association Studies for Albuminuria of Nondiabetic Taiwanese Population. | Yang WS et al. | β | 2023 | β |
| Genome-wide association studies in the Japanese population identified genetic loci and target gene associated with epidermal turnover. | Okuno R et al. | β | 2023 | β |
| Genome-Wide Association Studies of Diarrhea Frequency and Duration in the First Year of Life in Bangladeshi Infants. | Munday RM et al. | β | 2023 | β |
| Genome-wide association study identifies four pan-ancestry loci for suicidal ideation in the Million Veteran Program. | Ashley-Koch AE et al. | β | 2023 | β |
| Genome-wide association study identifies functional genomic variants associated with young stock survival in Nordic Red Dairy Cattle. | Cai Z et al. | β | 2023 | β |
| Genome-wide association study identifies novel candidate malaria resistance genes in Cameroon. | Esoh KK et al. | β | 2023 | β |
| Genome-wide association study identifies novel susceptibilities to adult moyamoya disease. | Jeon JP et al. | β | 2023 | β |
| Genome-wide association study in 404,302 individuals identifies 7 significant loci for reaction time variability. | Wootton O et al. | β | 2023 | β |
| Genome-wide association study meta-analysis of blood pressure traits and hypertension in sub-Saharan African populations: an AWI-Gen study. | Singh S et al. | β | 2023 | β |
| Genome-wide association study meta-analysis of suicide death and suicidal behavior. | Li QS et al. | β | 2023 | β |
| Genome-wide association study of antisocial personality disorder diagnostic criteria provides evidence for shared risk factors across disorders. | Li W et al. | β | 2023 | β |
| Genome-Wide Association Study of Chronic Dizziness in the Elderly Identifies Loci Implicating MLLT10, BPTF, LINC01224, and ROS1. | Clifford R et al. | β | 2023 | β |
| Genome-wide association study of chronic sputum production implicates loci involved in mucus production and infection. | Packer RJ et al. | β | 2023 | β |
| Genome-Wide Association Study of CKD Progression. | Robinson-Cohen C et al. | β | 2023 | β |
| Genome-wide association study of early ischaemic stroke risk in Brazilian individuals with sickle cell disease implicates ADAMTS2 and CDK18 and uncovers novel loci. | Earley EJ et al. | β | 2023 | β |
| Genome-wide association study of esophageal squamous cell cancer identifies shared and distinct risk variants in African and Chinese populations. | Chen WC et al. | β | 2023 | β |
| Genome-wide association study of hippocampal blood-oxygen-level-dependent-cerebral blood flow correlation in Chinese Han population. | Xue H et al. | β | 2023 | β |
| Genome-wide association study of population-standardised cognitive performance phenotypes in a rural South African community. | Soo CC et al. | β | 2023 | β |
| Genome-wide association study of tuberculosis in the western Chinese Han and Tibetan population. | Bai H et al. | β | 2023 | β |
| Genome-wide association study on coordination and agility in 461 Chinese Han males. | Wang Y et al. | β | 2023 | β |
| Genome-Wide Association Study Reveals <i>CLEC7A</i> and <i>PROM1</i> as Potential Regulators of <i>Paracoccidioides brasiliensis</i>-Induction of Cytokine Production in Peripheral Blood Mononuclear Cells. | de Figueiredo AMB et al. | β | 2023 | β |
| Genome-wide contribution of common short-tandem repeats to Parkinson's disease genetic risk. | Bustos BI et al. | β | 2023 | β |
| Genome-wide host-pathogen analyses reveal genetic interaction points in tuberculosis disease. | Phelan J et al. | β | 2023 | β |
| Genome-wide Interaction Study with Smoking for Colorectal Cancer Risk Identifies Novel Genetic Loci Related to Tumor Suppression, Inflammation, and Immune Response. | Carreras-Torres R et al. | β | 2023 | β |
| Genome-wide study of genetic polymorphisms predictive for outcome from first-line oxaliplatin-based chemotherapy in colorectal cancer patients. | Park HA et al. | β | 2023 | β |
| Genomic study of maternal lipid traits in early pregnancy concurs with four known adult lipid loci. | Ouidir M et al. | β | 2023 | β |
| Genotyping and population characteristics of the China Kadoorie Biobank. | Walters RG et al. | β | 2023 | β |
| GWAs Identify DNA Variants Influencing Eyebrow Thickness Variation in Europeans and Across Continental Populations. | Peng F et al. | β | 2023 | β |
| GWAS reveals genetic basis of a predisposition to severe COVID-19 through <i>in silico</i> modeling of the FYCO1 protein. | Gusakova MS et al. | β | 2023 | β |
| GWASs Identify Genetic Loci Associated with Human Scalp Hair Whorl Direction. | Luo J et al. | β | 2023 | β |
| HLA-DQA1*05 and upstream variants of PPARGC1B are associated with infliximab persistence in Japanese Crohn's disease patients. | Shimoda F et al. | β | 2023 | β |
| Human variation impacting <i>MCOLN2</i> restricts <i>Salmonella</i> Typhi replication by magnesium deprivation. | Gibbs KD et al. | β | 2023 | β |
| Identification of Distinct Genetic Profiles of Palindromic Rheumatism Using Whole-Exome Sequencing. | Zheng C et al. | β | 2023 | β |
| Identification of genetic variants associated with anterior cruciate ligament rupture and AKC standard coat color in the Labrador Retriever. | Lee BT et al. | β | 2023 | β |
| Identification of genetic variants associated with diabetic kidney disease in multiple Korean cohorts via a genome-wide association study mega-analysis. | Jin H et al. | β | 2023 | β |
| Identification of Novel, Replicable Genetic Risk Loci for Suicidal Thoughts and Behaviors Among US Military Veterans. | Kimbrel NA et al. | β | 2023 | β |
| Identification of potential genetic Loci and polygenic risk model for Budd-Chiari syndrome in Chinese population. | Hu X et al. | β | 2023 | β |
| Identification of Reduced ERAP2 Expression and a Novel HLA Allele as Components of a Risk Score for Susceptibility to Liver Injury Due to Amoxicillin-Clavulanate. | Nicoletti P et al. | β | 2023 | β |
| Identification of Sex-Specific Genetic Polymorphisms Associated with Asthma in Middle-Aged and Older Canadian Adults: An Analysis of CLSA Data. | Odimba U et al. | β | 2023 | β |
| Identifying Rare Genetic Determinants for Improved Polygenic Risk Prediction of Bone Mineral Density and Fracture Risk. | Lu T et al. | β | 2023 | β |
| Immune-response 3'UTR alternative polyadenylation quantitative trait loci contribute to variation in human complex traits and diseases. | Li L et al. | β | 2023 | β |
| Immunosuppression causes dynamic changes in expression QTLs in psoriatic skin. | Xiao Q et al. | β | 2023 | β |
| Inhibiting membrane rupture with NINJ1 antibodies limits tissue injury. | Kayagaki N et al. | β | 2023 | β |
| Insights into the genetics of menopausal vasomotor symptoms: genome-wide analyses of routinely-collected primary care health records. | Ruth KS et al. | β | 2023 | β |
| Integrating eQTL and GWAS data characterises established and identifies novel migraine risk loci. | Ghaffar A et al. | β | 2023 | β |
| Invited review: Good practices in genome-wide association studies to identify candidate sequence variants in dairy cattle. | Sahana G et al. | β | 2023 | β |
| Joint multi-ancestry and admixed GWAS reveals the complex genetics behind human cranial vault shape. | Goovaerts S et al. | β | 2023 | β |
| KidneyGPS: a user-friendly web application to help prioritize kidney function genes and variants based on evidence from genome-wide association studies. | Stanzick KJ et al. | β | 2023 | β |
| Leveraging genetic overlap between irritability and psychiatric disorders to identify genetic variants of major psychiatric disorders. | Jung K et al. | β | 2023 | β |
| Loci for insulin processing and secretion provide insight into type 2 diabetes risk. | Broadaway KA et al. | β | 2023 | β |
| Longitudinal lung function and gas transfer in individuals with idiopathic pulmonary fibrosis: a genome-wide association study. | Allen RJ et al. | β | 2023 | β |
| Low and high serum IgG associates with respiratory infections in a young and working age population. | Holma P et al. | β | 2023 | β |
| Machine learning-based quantification for disease uncertainty increases the statistical power of genetic association studies. | Park JY et al. | β | 2023 | β |
| Major Genetic Risk Factors for Dupuytren's Disease Are Inherited From Neandertals. | Γ gren R et al. | β | 2023 | β |
| Metabolome-Wide Mendelian Randomization Assessing the Causal Relationship Between Blood Metabolites and Bone Mineral Density. | Chen S et al. | β | 2023 | β |
| Multi-ancestry genome-wide analysis identifies shared genetic effects and common genetic variants for self-reported sleep duration. | Scammell BH et al. | β | 2023 | β |
| Multiomic prioritisation of risk genes for anorexia nervosa. | Adams DM et al. | β | 2023 | β |
| Multi-population genome-wide association study implicates immune and non-immune factors in pediatric steroid-sensitive nephrotic syndrome. | Barry A et al. | β | 2023 | β |
| Multi-trait genome-wide association analyses leveraging alcohol use disorder findings identify novel loci for smoking behaviors in the Million Veteran Program. | Cheng Y et al. | β | 2023 | β |
| Multivariate GWAS analysis reveals loci associated with liver functions in continental African populations. | Soremekun C et al. | β | 2023 | β |
| Novel genetic variants associated with inhaled corticosteroid treatment response in older adults with asthma. | Wang AL et al. | β | 2023 | β |
| Novel Genome-Wide Interactions Mediated via BOLL and EDNRA Polymorphisms in Intracranial Aneurysm. | Hong EP et al. | β | 2023 | β |
| Novel loci for Alzheimer's disease identified by a genome-wide association study in Ashkenazi Jews. | Li D et al. | β | 2023 | β |
| Pan-cancer and cross-population genome-wide association studies dissect shared genetic backgrounds underlying carcinogenesis. | Sato G et al. | β | 2023 | β |
| Plasma cortisol-linked gene networks in hepatic and adipose tissues implicate corticosteroid-binding globulin in modulating tissue glucocorticoid action and cardiovascular risk. | Bankier S et al. | β | 2023 | β |
| Post-GWAS screening of candidate genes for refractive error in mutant zebrafish models. | Quint WH et al. | β | 2023 | β |
| Potentially Functional Genetic Variants in the NRF2 Signaling Pathway Genes are Associated With HBV-related Hepatocellular Carcinoma Survival. | Gong R et al. | β | 2023 | β |
| Potential risk factors and genetic variants associated with dental caries incidence in Appalachia using genome-wide survival analysis. | Zou T et al. | β | 2023 | β |
| Probing the diabetes and colorectal cancer relationship using gene - environment interaction analyses. | Dimou N et al. | β | 2023 | β |
| Reduced Vrk2 expression is associated with higher risk of depression in humans and mediates depressive-like behaviors in mice. | Yin MY et al. | β | 2023 | β |
| Regulator of G-Protein Signalling 9: A New Candidate Gene for Sweet Food Liking? | Graham CA et al. | β | 2023 | β |
| RORB, an Alzheimer's disease susceptibility gene, is associated with viral encephalitis, an Alzheimer's disease risk factor. | Lehrer S et al. | β | 2023 | β |
| Sex-Specific Genetic Determinants of Asthma-COPD Phenotype and COPD in Middle-Aged and Older Canadian Adults: An Analysis of CLSA Data. | Odimba U et al. | β | 2023 | β |
| SGLT2 inhibitor ameliorates endothelial dysfunction associated with the common <i>ALDH2</i> alcohol flushing variant. | Guo H et al. | β | 2023 | β |
| Shared genetics and bidirectional causal relationships between type 2 diabetes and attention-deficit/hyperactivity disorder. | Baranova A et al. | β | 2023 | β |
| Single-nucleotide polymorphisms link gout with health-related lifestyle factors in Korean cohorts. | Jeon HK et al. | β | 2023 | β |
| Status and physiological significance of circulating adiponectin in the very old and centenarians: an observational study. | Sasaki T et al. | β | 2023 | β |
| Sub-cellular level resolution of common genetic variation in the photoreceptor layer identifies continuum between rare disease and common variation. | Currant H et al. | β | 2023 | β |
| Systematic Mendelian randomization study of the effect of gut microbiome and plasma metabolome on severe COVID-19. | Yan H et al. | β | 2023 | β |
| The Foundational Data Initiative for Parkinson Disease: Enabling efficient translation from genetic maps to mechanism. | Bressan E et al. | β | 2023 | β |
| The Genetic Architecture of Vitamin D Deficiency among an Elderly Lebanese Middle Eastern Population: An Exome-Wide Association Study. | Hendi NN et al. | β | 2023 | β |
| The genomics of visuospatial neurocognition in obsessive-compulsive disorder: A preliminary GWAS. | Alemany-Navarro M et al. | β | 2023 | β |
| The <i>KL</i> genetic polymorphisms Associated with type 2 diabetes Mellitus. | Jin HS et al. | β | 2023 | β |
| The IPDGC/GP2 Hackathon - an open science event for training in data science, genomics, and collaboration using Parkinson's disease data. | Leonard HL et al. | β | 2023 | β |
| The Type 2 Diabetes Knowledge Portal: An open access genetic resource dedicated to type 2 diabetes and related traits. | Costanzo MC et al. | β | 2023 | β |
| Time-varying effects are common in genetic control of gestational duration. | Juodakis J et al. | β | 2023 | β |
| TMEM132D and VIPR2 Polymorphisms as Genetic Risk Loci for Retinal Detachment: A Genome-Wide Association Study and Polygenic Risk Score Analysis. | Chuang HK et al. | β | 2023 | β |
| topr: an R package for viewing and annotating genetic association results. | Juliusdottir T | β | 2023 | β |
| Toward Identification of Functional Sequences and Variants in Noncoding DNA. | Monti R et al. | β | 2023 | β |
| TTLL11 gene is associated with sustained attention performance and brain networks: A genome-wide association study of a healthy Chinese sample. | Liu H et al. | β | 2023 | β |
| Whole-Exome Sequencing Analyses Support a Role of Vitamin D Metabolism in Ischemic Stroke. | Xie Y et al. | β | 2023 | β |
| Whole Genome Sequencing Identifies Novel Common and Low-Frequency Variants Associated With Age-Related Macular Degeneration. | Acar IE et al. | β | 2023 | β |
| X-linked genes influence various complex traits in dairy cattle. | Sanchez MP et al. | β | 2023 | β |
| Absence of association between host genetic mutations in the ORAI1 gene and COVID-19 fatality. | Shawer H et al. | β | 2022 | β |
| Absolute Neutrophil Count after the First Chemotherapy Cycle as a Surrogate Marker for Treatment Outcomes in Patients with Neuroblastoma. | Lee JW et al. | β | 2022 | β |
| A common variant in 11q23.3 associated with hyperlipidemia is mediated by the binding and regulation of GATA4. | Chou WC et al. | β | 2022 | β |
| Admixture Mapping of Sepsis in European Individuals With African Ancestries. | Hernandez-Beeftink T et al. | β | 2022 | β |
| A family-based study of genetic and epigenetic effects across multiple neurocognitive, motor, social-cognitive and social-behavioral functions. | Nudel R et al. | β | 2022 | β |
| A genome-wide association study for melatonin secretion. | Liu PH et al. | β | 2022 | β |
| A genome-wide association study for rheumatoid arthritis replicates previous HLA and non-HLA associations in a cohort from South Africa. | Mathebula EM et al. | β | 2022 | β |
| A genome-wide association study identified one variant associated with static spatial working memory in Chinese population. | Zhang L et al. | β | 2022 | β |
| A genome-wide association study identifies a novel association between SDC3 and apparent treatment-resistant hypertension. | Xiao X et al. | β | 2022 | β |
| A genome-wide association study in a large community-based cohort identifies multiple loci associated with susceptibility to bacterial and viral infections. | TΓ€ngdΓ©n T et al. | β | 2022 | β |
| A Genome-Wide Association Study into the Aetiology of Congenital Solitary Functioning Kidney. | Groen In 't Woud S et al. | β | 2022 | β |
| A Genome-Wide Association Study of Genetic Variants of Apolipoprotein A1 Levels and Their Association with Vitamin D in Korean Cohorts. | Lee Y et al. | β | 2022 | β |
| A genome-wide association study of plasma concentrations of warfarin enantiomers and metabolites in sub-Saharan black-African patients. | Asiimwe IG et al. | β | 2022 | β |
| A genome-wide association study of suicide attempts in the million veterans program identifies evidence of pan-ancestry and ancestry-specific risk loci. | Kimbrel NA et al. | β | 2022 | β |
| A Genome-Wide Association Study Reveals Two Genetic Markers for Chondromalacia. | Kim SK et al. | β | 2022 | β |
| A genome-wide association study with tissue transcriptomics identifies genetic drivers for classic bladder exstrophy. | Mingardo E et al. | β | 2022 | β |
| A genome-wide functional genomics approach uncovers genetic determinants of immune phenotypes in type 1 diabetes. | Chu X et al. | β | 2022 | β |
| A Genome-Wide Scan on Individual Typology AngleΒ Found Variants at SLC24A2 Associated withΒ Skin Color Variation in Chinese Populations. | Wang F et al. | β | 2022 | β |
| A GWAS Finds Variants at 2p21 Associated with Self-Reported Sensitive Skin in the Han Chinese Population. | Li B et al. | β | 2022 | β |
| A hidden layer of structural variation in transposable elements reveals potential genetic modifiers in human disease-risk loci. | van Bree EJ et al. | β | 2022 | β |
| A machine learning model using SNPs obtained from a genome-wide association study predicts the onset of vincristine-induced peripheral neuropathy. | Yamada H et al. | β | 2022 | β |
| Analyses of biomarker traits in diverse UK biobank participants identify associations missed by European-centric analysis strategies. | Sun Q et al. | β | 2022 | β |
| Analytic pipelines to assess the relationship between immune response and germline genetics in human tumors. | Sayaman RW et al. | β | 2022 | β |
| APOE and KLF14 genetic variants are sex-specific for low high-density lipoprotein cholesterol identified by a genome-wide association study. | Lee YH et al. | β | 2022 | β |
| A practical guideline of genomics-driven drug discovery in the era of global biobank meta-analysis. | Namba S et al. | β | 2022 | β |
| A single-cell atlas of human and mouse white adipose tissue. | Emont MP et al. | β | 2022 | β |
| Association between germline variants and somatic mutations in colorectal cancer. | Barfield R et al. | β | 2022 | β |
| Association between WWOX/MAF variants and dementia-related neuropathologic endophenotypes. | Dugan AJ et al. | β | 2022 | β |
| Association of Early Childhood Caries with Bitter Taste Receptors: A Meta-Analysis of Genome-Wide Association Studies and Transcriptome-Wide Association Study. | Orlova E et al. | β | 2022 | β |
| Association of Single-Nucleotide Variants in the Human Leukocyte Antigen and Other Loci With Childhood Hodgkin Lymphoma. | Chen C et al. | β | 2022 | β |
| A two-stage genome-wide association study to identify novel genetic loci associated with acute radiotherapy toxicity in nasopharyngeal carcinoma. | Wang Y et al. | β | 2022 | β |
| Beyond GWAS of Colorectal Cancer: Evidence of Interaction with Alcohol Consumption and Putative Causal Variant for the 10q24.2 Region. | Jordahl KM et al. | β | 2022 | β |
| Body mass index and adipose distribution have opposing genetic impacts on human blood traits. | Thom CS et al. | β | 2022 | β |
| Cancer Risk Score Prediction Based on a Single-Nucleotide Polymorphism Network. | Mahesworo B et al. | β | 2022 | β |
| Causal Association and Shared Genetics Between Asthma and COVID-19. | Baranova A et al. | β | 2022 | β |
| Chromosomal Region 11p14.1 is Associated with Pharmacokinetics and Pharmacodynamics of Bisoprolol. | Fontana V et al. | β | 2022 | β |
| Classification of early age facial growth pattern and identification of the genetic basis in two Korean populations. | Cha MY et al. | β | 2022 | β |
| Clotting factor genes are associated with preeclampsia in high-altitude pregnant women in the Peruvian Andes. | Nieves-ColΓ³n MA et al. | β | 2022 | β |
| Coding and Noncoding Variation in LRRK2 and Parkinson's Disease Risk. | Lake J et al. | β | 2022 | β |
| ColocQuiaL: a QTL-GWAS colocalization pipeline. | Chen BY et al. | β | 2022 | β |
| Common Variants Near ZIC1 and ZIC4 in Autopsy-Confirmed Multiple System Atrophy. | Hopfner F et al. | β | 2022 | β |
| Comprehensive genetic analysis of the human lipidome identifies loci associated with lipid homeostasis with links to coronary artery disease. | Cadby G et al. | β | 2022 | β |
| Congenital idiopathic megaesophagus in the German shepherd dog is a sex-differentiated trait and is associated with an intronic variable number tandem repeat in Melanin-Concentrating Hormone Receptor 2. | Bell SM et al. | β | 2022 | β |
| Control of naive and effector CD4 T cell receptor repertoires by rheumatoid-arthritis-risk HLA alleles. | Nagafuchi Y et al. | β | 2022 | β |
| COVID-19 and systemic lupus erythematosus genetics: A balance between autoimmune disease risk and protection against infection. | Wang Y et al. | β | 2022 | β |
| COVID-19 in pediatrics: Genetic susceptibility. | Glessner JT et al. | β | 2022 | β |
| Crohn's Disease and Early Exposure to Thiopurines are Independent Risk Factors for Mosaic Chromosomal Alterations in Patients with Inflammatory Bowel Diseases. | Kakuta Y et al. | β | 2022 | β |
| Deep learning-based identification of genetic variants: application to Alzheimer's disease classification. | Jo T et al. | β | 2022 | β |
| Diverse ancestry whole-genome sequencing association study identifies <i>TBX5</i> and <i>PTK7</i> as susceptibility genes for posterior urethral valves. | Chan MMY et al. | β | 2022 | β |
| Diverse functions associate with non-coding polymorphisms shared between humans and chimpanzees. | Velazquez-Arcelay K et al. | β | 2022 | β |
| Dyslipidaemia-Genotype Interactions with Nutrient Intake and Cerebro-Cardiovascular Disease. | Lee SB et al. | β | 2022 | β |
| Enhancing Discovery of Genetic Variants for Posttraumatic Stress Disorder Through Integration of Quantitative Phenotypes and Trauma Exposure Information. | Maihofer AX et al. | β | 2022 | β |
| ezQTL: A Web Platform for Interactive Visualization and Colocalization of QTLs and GWAS Loci. | Zhang T et al. | β | 2022 | β |
| Fine-mapping of intracranial aneurysm susceptibility based on a genome-wide association study. | Hong EP et al. | β | 2022 | β |
| First genome-wide association study of esophageal atresia identifies three genetic risk loci at <i>CTNNA3</i>, <i>FOXF1</i>/<i>FOXC2</i>/<i>FOXL1</i>, and <i>HNF1B</i>. | Gehlen J et al. | β | 2022 | β |
| Flashfm-ivis: interactive visualization for fine-mapping of multiple quantitative traits. | Zhou F et al. | β | 2022 | β |
| From musk to body odor: Decoding olfaction through genetic variation. | Li B et al. | β | 2022 | β |
| Functional annotation and investigation of the 10q24.33 melanoma risk locus identifies a common variant that influences transcriptional regulation of OBFC1. | Cardinale A et al. | β | 2022 | β |
| Genetically increased circulating FUT3 level leads to reduced risk of idiopathic pulmonary fibrosis: a Mendelian randomisation study. | Nakanishi T et al. | β | 2022 | β |
| Genetic analyses identify pleiotropy and causality for blood proteins and highlight Wnt/Ξ²-catenin signalling in migraine. | Tanha HM et al. | β | 2022 | β |
| Genetic Analyses of Enamel Hypoplasia in Multiethnic Cohorts. | Alotaibi RN et al. | β | 2022 | β |
| Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways. | Young WJ et al. | β | 2022 | β |
| Genetic Analysis in African American Children Supports Ancestry-Specific Neuroblastoma Susceptibility. | Testori A et al. | β | 2022 | β |
| Genetic analysis of the PCSK9 locus in psychological, psychiatric, metabolic and cardiovascular traits in UK Biobank. | Hay R et al. | β | 2022 | β |
| Genetic and environmental etiology of drinking motives in college students. | Savage JE et al. | β | 2022 | β |
| Genetic association of primary nonresponse to anti-TNFΞ± therapy in patients with inflammatory bowel disease. | De T et al. | β | 2022 | β |
| Genetic common variants associated with cerebellar volume and their overlap with mental disorders: a study on 33,265 individuals from the UK-Biobank. | Chambers T et al. | β | 2022 | β |
| Genetic Contributors of Efficacy and Adverse Metabolic Effects of Chlorthalidone in African Americans from the Genetics of Hypertension Associated Treatments (GenHAT) Study. | Armstrong ND et al. | β | 2022 | β |
| Genetic Polymorphisms Associated with Prothrombin Time and Activated Partial Thromboplastin Time in Chinese Healthy Population. | Zhang F et al. | β | 2022 | β |
| Genetic regulation of post-translational modification of two distinct proteins. | Landini A et al. | β | 2022 | β |
| Genetic regulation of RNA splicing in human pancreatic islets. | Atla G et al. | β | 2022 | β |
| Genetics are not likely to offer clinically useful predictions for elevated liver enzyme levels in patients using low dose methotrexate. | Cui J et al. | β | 2022 | β |
| Genetics of osteopontin in patients with chronic kidney disease: The German Chronic Kidney Disease study. | Cheng Y et al. | β | 2022 | β |
| Genetic susceptibility loci for <i>Chlamydia trachomatis</i> endometrial infection influence expression of genes involved in T cell function, tryptophan metabolism and epithelial integrity. | Zhong W et al. | β | 2022 | β |
| Genetic variants in CYP2B6 and HSD17B12 associated with risk of squamous cell carcinoma of the head and neck. | Liu H et al. | β | 2022 | β |
| Genetic variations in relation to bleeding and pharmacodynamics of dabigatran in Chinese patients with nonvalvular atrial fibrillation: A nationwide multicentre prospective cohort study. | Xiang Q et al. | β | 2022 | β |
| Genome and transcriptome profiling of spontaneous preterm birth phenotypes. | Gupta JK et al. | β | 2022 | β |
| Genome- and Transcriptome-Wide Association Studies Identify Susceptibility Genes and Pathways for Periodontitis. | Zhu G et al. | β | 2022 | β |
| Genome-wide analysis identify novel germline genetic variations in <i>ADCY1</i> influencing platinum-based chemotherapy response in non-small cell lung cancer. | Mao C et al. | β | 2022 | β |
| Genome-wide and phenome-wide analysis of ideal cardiovascular health in the VA Million Veteran Program. | Huang RDL et al. | β | 2022 | β |
| Genome-wide and transcriptome-wide association studies of mammographic density phenotypes reveal novel loci. | Chen H et al. | β | 2022 | β |
| Genome-wide associated variants of subclinical atherosclerosis among young people with HIV and gene-environment interactions. | He J et al. | β | 2022 | β |
| Genome-Wide Association Analysis and Genomic Prediction of Thyroglobulin Plasma Levels. | PleiΔ N et al. | β | 2022 | β |
| Genome-wide association analysis reveals new insights into the genetic architecture of defensive, agro-morphological and quality-related traits in cassava. | Rabbi IY et al. | β | 2022 | β |
| Genome-wide Association and Meta-analysis of Age at Onset in Parkinson Disease: Evidence From the COURAGE-PD Consortium. | Grover S et al. | β | 2022 | β |
| Genome-wide association of polygenic risk extremes for Alzheimer's disease in the UK Biobank. | Gouveia C et al. | β | 2022 | β |
| Genome-wide association studies identify novel genetic loci for epigenetic age acceleration among survivors of childhood cancer. | Dong Q et al. | β | 2022 | β |
| Genome-wide association studies in Japanese women identified genetic loci associated with wrinkles and sagging. | Okuno R et al. | β | 2022 | β |
| Genome-wide association study and functional validation implicates JADE1 in tauopathy. | Farrell K et al. | β | 2022 | β |
| Genome-Wide Association Study and Gene-Based Analysis of Participants With Hemophilia A and Inhibitors in the My Life, Our Future Research Repository. | Lessard S et al. | β | 2022 | β |
| Genome-wide association study finds multiple loci associated with intraocular pressure in HS rats. | Fowler S et al. | β | 2022 | β |
| Genome-Wide Association Study for eGFR in a Taiwanese Population. | Chen YC et al. | β | 2022 | β |
| Genome-Wide Association Study Identifies Genetic Loci Associated With Fat Cell Number and Overlap With Genetic Risk Loci for Type 2 Diabetes. | KulytΓ© A et al. | β | 2022 | β |
| Genome-wide association study identifies genetic risk loci for adiposity in a Taiwanese population. | Wong HS et al. | β | 2022 | β |
| Genome-wide association study identifies novel loci associated with skin autofluorescence in individuals without diabetes. | Vollenbrock CE et al. | β | 2022 | β |
| Genome-wide association study identifies SjΓΆgren's risk loci with functional implications in immune and glandular cells. | Khatri B et al. | β | 2022 | β |
| Genome-wide association study identifies TNFSF15 associated with childhood asthma. | Kim KW et al. | β | 2022 | β |
| Genome-wide Association Study of Axial Length in Population-based Cohorts in Japan: The Tohoku Medical Megabank Organization Eye Study. | Fuse N et al. | β | 2022 | β |
| Genome-wide association study of colorectal polyps identified highly overlapping polygenic architecture with colorectal cancer. | Hikino K et al. | β | 2022 | β |
| Genome-wide association study of dermatophytosis in the UK Biobank cohort. | Lehrer S et al. | β | 2022 | β |
| Genome-Wide Association Study of Fluorescent Oxidation Products Accounting for Tobacco Smoking Status in Adults from the French EGEA Study. | Orsi L et al. | β | 2022 | β |
| Genome-wide association study of idiopathic hypersomnia in a Japanese population. | Tanida K et al. | β | 2022 | β |
| Genome-Wide Association Study of Incident Dementia in a Community-Based Sample of Older Subjects. | Harper JD et al. | β | 2022 | β |
| Genome-wide association study of occupational attainment as a proxy for cognitive reserve. | Ko H et al. | β | 2022 | β |
| Genome-wide association study of posttraumatic stress disorder among childhood cancer survivors: results from the Childhood Cancer Survivor Study and the St. Jude Lifetime Cohort. | Lu D et al. | β | 2022 | β |
| Genomewide Association Study of Retinal Traits in the Amish Reveals Loci Influencing Drusen Development and Link to Age-Related Macular Degeneration. | Osterman MD et al. | β | 2022 | β |
| Genome-wide association study reveals the genetic basis of brace root angle and diameter in maize. | Sun D et al. | β | 2022 | β |
| Genome-wide by Environment Interaction Study of Stressful Life Events and Hospital-Treated Depression in the iPSYCH2012 Sample. | Suppli NP et al. | β | 2022 | β |
| Genome-wide gene-air pollution interaction analysis of lung function in 300,000 individuals. | Melbourne CA et al. | β | 2022 | β |
| Genome-wide gene-gene interaction of the 5-HTTLPR promoter polymorphism emphasizes the important role of neuroplasticity in depression. | Garvert L et al. | β | 2022 | β |
| Genome-Wide Interaction Analysis of Genetic Variants With Menopausal Hormone Therapy for Colorectal Cancer Risk. | Tian Y et al. | β | 2022 | β |
| Genome-wide meta-analysis identifies susceptibility loci for autoimmune hepatitis type 1. | Li Y et al. | β | 2022 | β |
| Genome-wide meta-analysis of alcohol use disorder in East Asians. | Zhou H et al. | β | 2022 | β |
| Genome-wide Scan of Dental Fear and Anxiety Nominates Novel Genes. | Zhou Y et al. | β | 2022 | β |
| GWAS and ExWAS of blood mitochondrial DNA copy number identifies 71 loci and highlights a potential causal role in dementia. | Chong M et al. | β | 2022 | β |
| GWAS identifies candidate susceptibility loci and microRNA biomarkers for acute encephalopathy with biphasic seizures and late reduced diffusion. | Kasai M et al. | β | 2022 | β |
| GWAS meta-analysis of intrahepatic cholestasis of pregnancy implicates multiple hepatic genes and regulatory elements. | Dixon PH et al. | β | 2022 | β |
| H3AGWAS: a portable workflow for genome wide association studies. | Brandenburg JT et al. | β | 2022 | β |
| Human genetic diversity regulating the <i>TLR10/TLR1/TLR6</i> locus confers increased cytokines in response to <i>Chlamydia trachomatis</i>. | Barnes AB et al. | β | 2022 | β |
| Identification and Validation of Candidate Genes from Genome-Wide Association Studies. | Albert E et al. | β | 2022 | β |
| Identification of a novel genetic locus associated with immune-mediated thrombotic thrombocytopenic purpura. | Stubbs MJ et al. | β | 2022 | β |
| Identification of five genetic variants with differential effects on obesity-related traits based on age. | Chung JY et al. | β | 2022 | β |
| Identification of Novel Loci Involved in Adalimumab Response in Crohn's Disease Patients Using Integration of Genome Profiling and Isoform-Level Immune-Cell Deconvoluted Transcriptome Profiling of Colon Tissue. | Gorenjak M et al. | β | 2022 | β |
| Improving lithium dose prediction using population pharmacokinetics and pharmacogenomics: a cohort genome-wide association study in Sweden. | Millischer V et al. | β | 2022 | β |
| Innovative computational approaches shed light on genetic mechanisms underlying cognitive impairment among children born extremely preterm. | Liu W et al. | β | 2022 | β |
| Integrated GWAS and Gene Expression Suggest ORM1 as a Potential Regulator of Plasma Levels of Cell-Free DNA and Thrombosis Risk. | Lopez S et al. | β | 2022 | β |
| Integrating single-cell sequencing data with GWAS summary statistics reveals CD16+monocytes and memory CD8+T cells involved in severe COVID-19. | Ma Y et al. | β | 2022 | β |
| Integration of multidimensional splicing data and GWAS summary statistics for risk gene discovery. | Ji Y et al. | β | 2022 | β |
| Integrative genetics-metabolomics analysis of infant bronchiolitis-childhood asthma link: A multicenter prospective study. | Ooka T et al. | β | 2022 | β |
| Investigating the genetic architecture of eye colour in a Canadian cohort. | Lona-Durazo F et al. | β | 2022 | β |
| <i>SLC4A4</i>, <i>FRAS1</i>, and <i>SULT1A1</i> Genetic Variations Associated With Dabigatran Metabolism in a Healthy Chinese Population. | Xie Q et al. | β | 2022 | β |
| Large-scale genomic analyses reveal insights into pleiotropy across circulatory system diseases and nervous system disorders. | Zhang X et al. | β | 2022 | β |
| Limb development genes underlie variation in human fingerprint patterns. | Li J et al. | β | 2022 | β |
| Mechanisms of pre-attachment Striga resistance in sorghum through genome-wide association studies. | Mallu TS et al. | β | 2022 | β |
| Meta-GWAS Reveals Novel Genetic Variants Associated with Urinary Excretion of Uromodulin. | Joseph CB et al. | β | 2022 | β |
| Methods for statistical fine-mapping and their applications to auto-immune diseases. | Wang QS et al. | β | 2022 | β |
| Multi-ethnic GWAS and fine-mapping of glycaemic traits identify novel loci in the PAGE Study. | Downie CG et al. | β | 2022 | β |
| Mycobacterium abscessus pathogenesis identified by phenogenomic analyses. | Boeck L et al. | β | 2022 | β |
| Neuron-derived neuropeptide Y fine-tunes the splenic immune responses. | Yu J et al. | β | 2022 | β |
| No replication of previously reported association with genetic variants in the T cell receptor alpha (TRA) locus for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). | Ueland M et al. | β | 2022 | β |
| Pharmacogenetics of Between-Individual Variability in Plasma Clearance of Bedaquiline and Clofazimine in South Africa. | Haas DW et al. | β | 2022 | β |
| Pinpointing novel risk loci for Lewy body dementia and the shared genetic etiology with Alzheimer's disease and Parkinson's disease: a large-scale multi-trait association analysis. | Guo P et al. | β | 2022 | β |
| Polygenic risk score trend and new variants on chromosome 1 are associated with male gout in genome-wide association study. | Chang YS et al. | β | 2022 | β |
| Potentially functional genetic variants of VAV2 and PSMA4 in the immune-activation pathway and non-small cell lung cancer survival. | Bai Y et al. | β | 2022 | β |
| Potential role of regulatory DNA variants in modifying the risk of severe cutaneous reactions induced by aromatic anti-seizure medications. | Mullan KA et al. | β | 2022 | β |
| Quality assessment and refinement of chromatin accessibility data using a sequence-based predictive model. | Han SK et al. | β | 2022 | β |
| Ratios of Acetaminophen Metabolites Identify New Loci of Pharmacogenetic Relevance in a Genome-Wide Association Study. | Thareja G et al. | β | 2022 | β |
| Recessive Genome-Wide Meta-analysis Illuminates Genetic Architecture of Type 2 Diabetes. | O'Connor MJ et al. | β | 2022 | β |
| Regulation of CIRP by genetic factors of SP1 related to cold sensitivity. | Kim SY et al. | β | 2022 | β |
| Regulation of mitophagy by the NSL complex underlies genetic risk for Parkinson's disease at 16q11.2 and MAPT H1 loci. | Soutar MPM et al. | β | 2022 | β |
| Secondary analyses for genome-wide association studies using expression quantitative trait loci. | Ngwa JS et al. | β | 2022 | β |
| Sex-specific genetic modifiers identified susceptibility of cold stored red blood cells to osmotic hemolysis. | Fang F et al. | β | 2022 | β |
| Shared genetic influences between blood analyte levels and risk of severe COVID-19. | Tanha HM et al. | β | 2022 | β |
| Subcutaneous adipose tissue splice quantitative trait loci reveal differences in isoform usage associated with cardiometabolic traits. | Brotman SM et al. | β | 2022 | β |
| Systematic analysis of the effects of genetic variants on chromatin accessibility to decipher functional variants in non-coding regions. | Wang D et al. | β | 2022 | β |
| Systematic single-variant and gene-based association testing of thousands of phenotypes in 394,841Β UK Biobank exomes. | Karczewski KJ et al. | β | 2022 | β |
| TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A. | Brown AL et al. | β | 2022 | β |
| TDP-43 represses cryptic exon inclusion in the FTD-ALS gene UNC13A. | Ma XR et al. | β | 2022 | β |
| The bacterial effector GarD shields Chlamydia trachomatis inclusions from RNF213-mediated ubiquitylation and destruction. | Walsh SC et al. | β | 2022 | β |
| The functional role of inherited CDKN2A variants in childhood acute lymphoblastic leukemia. | Li C et al. | β | 2022 | β |
| The Genetic Basis for the Increased Prevalence of Metabolic Syndrome among Post-Traumatic Stress Disorder Patients. | Misganaw B et al. | β | 2022 | β |
| The HDAC9-associated risk locus promotes coronary artery disease by governing TWIST1. | Ma L et al. | β | 2022 | β |
| Transcript levels in plasma contribute substantial predictive value as potential Alzheimer's disease biomarkers in African Americans. | Reddy JS et al. | β | 2022 | β |
| Trans-Ethnic Meta-Analysis of Interactions Between Genetics and Early-Life Socioeconomic Context on Memory Performance and Decline in Older Americans. | Faul JD et al. | β | 2022 | β |
| Understanding the function of regulatory DNA interactions in the interpretation of non-coding GWAS variants. | Zhong W et al. | β | 2022 | β |
| Unveiling genetic variants for age-related sarcopenia by conducting a genome-wide association study on Korean cohorts. | Jin H et al. | β | 2022 | β |
| Validation of Polygenic Risk Scores for Coronary Heart Disease in a Middle Eastern Cohort Using Whole Genome Sequencing. | Saad M et al. | β | 2022 | β |
| Variability of Primary SjΓΆgren's Syndrome Is Driven by Interferon-Ξ± and Interferon-Ξ± Blood Levels Are Associated With the Class II HLA-DQ Locus. | Trutschel D et al. | β | 2022 | β |
| Variation in the fruit development gene POINTED TIP regulates protuberance of tomato fruit tip. | Song J et al. | β | 2022 | β |
| Verification of immunology-related genetic associations in BPD supports ABCA3 and five other genes. | Blume F et al. | β | 2022 | β |
| Vitronectin and Its Interaction with PAI-1 Suggests a Functional Link to Vascular Changes in AMD Pathobiology. | Biasella F et al. | β | 2022 | β |
| Your height affects your health: genetic determinants and health-related outcomes in Taiwan. | Chiou JS et al. | β | 2022 | β |
| 3D facial phenotyping by biometric sibling matching used in contemporary genomic methodologies. | Hoskens H et al. | β | 2021 | β |
| A comprehensive analysis of SNPs and CNVs identifies novel markers associated with disease outcomes in colorectal cancer. | Yu Y et al. | β | 2021 | β |
| Admixture/fine-mapping in Brazilians reveals a West African associated potential regulatory variant (rs114066381) with a strong female-specific effect on body mass and fat mass indexes. | Scliar MO et al. | β | 2021 | β |
| Admixture mapping reveals the association between Native American ancestry at 3q13.11 and reduced risk of Alzheimer's disease in Caribbean Hispanics. | Horimoto ARVR et al. | β | 2021 | β |
| A Functional SNP in the Promoter of <i>LBX1</i> Is Associated With the Development of Adolescent Idiopathic Scoliosis Through Involvement in the Myogenesis of Paraspinal Muscles. | Xu L et al. | β | 2021 | β |
| A genetic link between risk for Alzheimer's disease and severe COVID-19 outcomes via the OAS1 gene. | Magusali N et al. | β | 2021 | β |
| A Genetic Study of Cerebral Atherosclerosis Reveals Novel Associations with <i>NTNG1</i> and CNOT3. | Vattathil SM et al. | β | 2021 | β |
| A Genome-wide Association Study for Concussion Risk. | Kim SK et al. | β | 2021 | β |
| A genome-wide association study identifies 5 loci associated with frozen shoulder and implicates diabetes as a causal risk factor. | Green HD et al. | β | 2021 | β |
| A genome-wide association study identifies a novel candidate locus at the DLGAP1 gene with susceptibility to resistant hypertension in the Japanese population. | Takahashi Y et al. | β | 2021 | β |
| A Genome-wide Association Study Identifies SERPINB10, CRLF3, STX7, LAMP3, IFNG-AS1, and KRT80 As Risk Loci Contributing to Cutaneous Leishmaniasis in Brazil. | Castellucci LC et al. | β | 2021 | β |
| A genome-wide association study of quantitative computed tomographic emphysema in Korean populations. | Sin S et al. | β | 2021 | β |
| A genome-wide association study of the longitudinal course of executive functions. | Wendel B et al. | β | 2021 | β |
| A genome-wide association study on confection consumption in a Japanese population: the Japan Multi-Institutional Collaborative Cohort Study. | Suzuki T et al. | β | 2021 | β |
| A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's disease. | Wightman DP et al. | β | 2021 | β |
| A Germline Variant at 8q24 Contributes to the Serum p2PSA Level in a Chinese Prostate Biopsy Cohort. | Lin X et al. | β | 2021 | β |
| A missense variant in SHARPIN mediates Alzheimer's disease-specific brain damages. | Park JY et al. | β | 2021 | β |
| Analyses of nicotine metabolism biomarker genetics stratified by sex in African and European Americans. | Chenoweth MJ et al. | β | 2021 | β |
| Analyses stratified by maternal age and recombination further characterize genes associated with maternal nondisjunction of chromosome 21. | Chernus JM et al. | β | 2021 | β |
| Analysis of genes (TMEM106B, GRN, ABCC9, KCNMB2, and APOE) implicated in risk for LATE-NC and hippocampal sclerosis provides pathogenetic insights: a retrospective genetic association study. | Dugan AJ et al. | β | 2021 | β |
| An atlas of alternative polyadenylation quantitative trait loci contributing to complex trait and disease heritability. | Li L et al. | β | 2021 | β |
| Aotearoa New Zealand MΔori and Pacific Population-amplified Gout Risk Variants: <i>CLNK</i> Is a Separate Risk Gene at the <i>SLC2A9</i> Locus. | Ji A et al. | β | 2021 | β |
| APOC3 genetic variation, serum triglycerides, and risk of coronary artery disease in Asian Indians, Europeans, and other ethnic groups. | Goyal S et al. | β | 2021 | β |
| ARHGEF26 enhances Salmonella invasion and inflammation in cells and mice. | Bourgeois JS et al. | β | 2021 | β |
| Assessment of ANG variants in Parkinson's disease. | Grenn FP et al. | β | 2021 | β |
| Association among extracellular superoxide dismutase genotype, plasma concentration, and comorbidity in the very old and centenarians. | Sasaki T et al. | β | 2021 | β |
| Association Between NEDD4L Variation and the Genetic Risk of Acute Appendicitis: A Multi-institutional Genome-Wide Association Study. | Gaitanidis A et al. | β | 2021 | β |
| Association of COA1 with Patellar Tendonitis: A Genome-wide Association Analysis. | Kim SK et al. | β | 2021 | β |
| Association of DLL1 with type 1 diabetes in patients characterized by low polygenic risk score. | Qu J et al. | β | 2021 | β |
| Association of genetic variants of FBXO32 and FOXO6 in the FOXO pathway with breast cancer risk. | Wang H et al. | β | 2021 | β |
| Association of genetic variants of <i>TMEM135</i> and <i>PEX5</i> in the peroxisome pathway with cutaneous melanoma-specific survival. | Wang H et al. | β | 2021 | β |
| Association of Novel Locus With Rheumatic Heart Disease in Black African Individuals: Findings From the RHDGen Study. | Machipisa T et al. | β | 2021 | β |
| A unified framework identifies new links between plasma lipids and diseases from electronic medical records across large-scale cohorts. | Veturi Y et al. | β | 2021 | β |
| A web-based survey on various symptoms of computer vision syndrome and the genetic understanding based on a multi-trait genome-wide association study. | Yoshimura K et al. | β | 2021 | β |
| Beta-lactam-induced immediate hypersensitivity reactions: AΒ genome-wide association study of a deeply phenotyped cohort. | Nicoletti P et al. | β | 2021 | β |
| Carrot Consumption Frequency Associated with Reduced BMI and Obesity through the SNP Intermediary rs4445711. | Fujihara K et al. | β | 2021 | β |
| Cell-type-specific expression quantitative trait loci associated with Alzheimer disease in blood and brain tissue. | Patel D et al. | β | 2021 | β |
| Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. | Panyard DJ et al. | β | 2021 | β |
| Cigarette smoking-associated isoform switching and 3' UTR lengthening via alternative polyadenylation. | Xu Z et al. | β | 2021 | β |
| Circulating Adiponectin and Its Association with Metabolic Traits and Type 2 Diabetes: Gene-Diet Interactions Focusing on Selected Gene Variants and at the Genome-Wide Level in High-Cardiovascular Risk Mediterranean Subjects. | Coltell O et al. | β | 2021 | β |
| Class II Human Leukocyte Antigen Variants Associate With Risk of Pegaspargase Hypersensitivity. | Liu Y et al. | β | 2021 | β |
| Common and Rare Genetic Variants That Could Contribute to Severe Otitis Media in an Australian Aboriginal Population. | Jamieson SE et al. | β | 2021 | β |
| Coping with brain amyloid: genetic heterogeneity and cognitive resilience to Alzheimer's pathophysiology. | Ramanan VK et al. | β | 2021 | β |
| Copy Number Variant Analysis and Genome-wide Association Study Identify Loci with Large Effect for Vesicoureteral Reflux. | Verbitsky M et al. | β | 2021 | β |
| CPNE3 moderates the association between anxiety and working memory. | Chen C et al. | β | 2021 | β |
| Detecting Gene-Environment Interaction for Maternal Exposures Using Case-Parent Trios Ascertained Through a Case With Non-Syndromic Orofacial Cleft. | Zhang W et al. | β | 2021 | β |
| Dietary Habit Is Associated with Depression and Intelligence: An Observational and Genome-Wide Environmental Interaction Analysis in the UK Biobank Cohort. | Cheng B et al. | β | 2021 | β |
| Discovery and Mediation Analysis of Cross-Phenotype Associations Between Asthma and Body Mass Index in 12q13.2. | Salinas YD et al. | β | 2021 | β |
| Discovery of new genetic loci for male sexual orientation in Han population. | Hu SH et al. | β | 2021 | β |
| Dissecting indirect genetic effects from peers in laboratory mice. | Baud A et al. | β | 2021 | β |
| DNA Repair Gene Polymorphisms and Chromosomal Aberrations in Exposed Populations. | Niazi Y et al. | β | 2021 | β |
| DNA repair gene polymorphisms and chromosomal aberrations in healthy, nonsmoking population. | Niazi Y et al. | β | 2021 | β |
| Donor genetic variants as risk factors for thrombosis after liver transplantation: A genome-wide association study. | Li Y et al. | β | 2021 | β |
| Dysregulation of Synaptic Signaling Genes Is Involved in Biology of Uterine Leiomyoma. | Krsteski J et al. | β | 2021 | β |
| Editing GWAS: experimental approaches to dissect and exploit disease-associated genetic variation. | Rao S et al. | β | 2021 | β |
| Efficient mixed model approach for large-scale genome-wide association studies of ordinal categorical phenotypes. | Bi W et al. | β | 2021 | β |
| eQTpLot: a user-friendly R package for the visualization of colocalization between eQTL and GWAS signals. | Drivas TG et al. | β | 2021 | β |
| Estimating prevalence of human traits among populations from polygenic risk scores. | Graham BE et al. | β | 2021 | β |
| Exome-Wide Association Study Identifies East Asian-Specific Missense Variant <i>MTHFR</i> C136T Influencing Homocysteine Levels in Chinese Populations RH: ExWAS of tHCY in a Chinese Population. | Liu T et al. | β | 2021 | β |
| Exploring human-genome gut-microbiome interaction in Parkinson's disease. | Wallen ZD et al. | β | 2021 | β |
| Expression quantitative trait loci for ETV4 and MEOX1 are associated with adult asthma in Japanese populations. | Yatagai Y et al. | β | 2021 | β |
| Extensive pleiotropism and allelic heterogeneity mediate metabolic effects of <i>IRX3</i> and <i>IRX5</i>. | Sobreira DR et al. | β | 2021 | β |
| Family-Based Genome-Wide Association Study of Autism Spectrum Disorder in Middle Eastern Families. | Al-Sarraj Y et al. | β | 2021 | β |
| FAT4 identified as a potential modifier of orofacial cleft laterality. | Curtis SW et al. | β | 2021 | β |
| Fibrin is a critical regulator of neutrophil effector function at the oral mucosal barrier. | Silva LM et al. | β | 2021 | β |
| First genome-wide association study on rocuronium dose requirements shows association with SLCO1A2. | AhlstrΓΆm S et al. | β | 2021 | β |
| From GWAS to Gene: Transcriptome-Wide Association Studies and Other Methods to Functionally Understand GWAS Discoveries. | Li B et al. | β | 2021 | β |
| Gene-Based Analysis Reveals Sex-Specific Genetic Risk Factors of COPD. | Joo J et al. | β | 2021 | β |
| Gene-level analysis of rare variants in 379,066 whole exome sequences identifies an association of GIGYF1 loss of function with type 2 diabetes. | Deaton AM et al. | β | 2021 | β |
| Genetically regulated expression underlies cellular sensitivity to chemotherapy in diverse populations. | Mulford AJ et al. | β | 2021 | β |
| Genetic and demographic predisposing factors associated with pediatric sleepwalking in the Philadelphia Neurodevelopmental Cohort. | Chiba Y et al. | β | 2021 | β |
| Genetic and Metabolic Determinants of Plasma Levels of ANGPTL8. | Oldoni F et al. | β | 2021 | β |
| Genetic architecture of type 1 diabetes with low genetic risk score informed by 41 unreported loci. | Qu HQ et al. | β | 2021 | β |
| Genetic association and characterization of FSTL5 in isolated clubfoot. | Khanshour AM et al. | β | 2021 | β |
| Genetic Contributors of Incident Stroke in 10,700 African Americans With Hypertension: A Meta-Analysis From the Genetics of Hypertension Associated Treatments and Reasons for Geographic and Racial Differences in Stroke Studies. | Armstrong ND et al. | β | 2021 | β |
| Genetic Determinants of Serum Calcification Propensity and Cardiovascular Outcomes in the General Population. | de Haan A et al. | β | 2021 | β |
| Genetic disruption of serine biosynthesis is a key driver of macular telangiectasia type 2 aetiology and progression. | Bonelli R et al. | β | 2021 | β |
| Genetic effects on liver chromatin accessibility identify disease regulatory variants. | Currin KW et al. | β | 2021 | β |
| Genetic Link Determining the Maternal-Fetal Circulation of Vitamin D. | Sampathkumar A et al. | β | 2021 | β |
| Genetic Predictors of Chemotherapy-Induced Peripheral Neuropathy from Paclitaxel, Carboplatin and Oxaliplatin: NCCTG/Alliance N08C1, N08CA and N08CB Study. | Adjei AA et al. | β | 2021 | β |
| Genetic predictors of severe intraventricular hemorrhage in extremely low-birthweight infants. | Thornburg CD et al. | β | 2021 | β |
| Genetic risk factors for colorectal cancer in multiethnic Indonesians. | Yusuf I et al. | β | 2021 | β |
| [Genetic study of cardiovascular disease subtypes defined by International Classification of Diseases]. | Guo ZN et al. | β | 2021 | β |
| Genetic Susceptibility Loci in Genomewide Association Study of Cluster Headache. | Harder AVE et al. | β | 2021 | β |
| Genetic susceptibility to hepatocellular carcinoma in chromosome 22q13.31, findings of a genome-wide association study. | Wang Z et al. | β | 2021 | β |
| Genetic variants associated with rotator cuff tearing utilizing multiple population-based genetic resources. | Tashjian RZ et al. | β | 2021 | β |
| Genetic variation in genes regulating skeletal muscle regeneration and tissue remodelling associated with weight loss in chronic obstructive pulmonary disease. | Lakshman Kumar P et al. | β | 2021 | β |
| Genetic Variation in the ASTN2 Locus in Cardiovascular, Metabolic and Psychiatric Traits: Evidence for Pleiotropy Rather Than Shared Biology. | Burt O et al. | β | 2021 | β |
| Genetic Variation in WNT9B Increases Relapse Hazard in Multiple Sclerosis. | Vandebergh M et al. | β | 2021 | β |
| Genetic Variations and Health-Related Quality of Life (HRQOL): A Genome-Wide Study Approach. | Adjei AA et al. | β | 2021 | β |
| Gene-Toxicant Interactions in Gulf War Illness: Differential Effects of the <i>PON1</i> Genotype. | Vahey J et al. | β | 2021 | β |
| Genome-wide analyses of multiple obesity-related cytokines and hormones informs biology of cardiometabolic traits. | Meeks KAC et al. | β | 2021 | β |
| Genome-wide analysis identifies a novel LINC-PINT splice variant associated with vascular amyloid pathology in Alzheimer's disease. | Reddy JS et al. | β | 2021 | β |
| Genome-wide association analysis reveals that EDNRB2 causes a dose-dependent loss of pigmentation in ducks. | Xi Y et al. | β | 2021 | β |
| Genome-Wide association between EYA1 and Aspirin-induced peptic ulceration. | Bourgeois S et al. | β | 2021 | β |
| Genome-wide association meta-analysis identifies pleiotropic risk loci for aerodigestive squamous cell cancers. | Lesseur C et al. | β | 2021 | β |
| Genome-Wide Association Meta-Analysis Supports Genes Involved in Valve and Cardiac Development to Associate With Mitral Valve Prolapse. | Yu M et al. | β | 2021 | β |
| Genome-Wide Association of Proprotein Convertase Subtilisin/Kexin Type 9 Plasma Levels in the ELSA-Brasil Study. | Bensenor I et al. | β | 2021 | β |
| Genome-wide association studies identify the role of caspase-9 in kidney disease. | Doke T et al. | β | 2021 | β |
| Genome-wide association studies identify two novel loci conferring susceptibility to diabetic retinopathy in Japanese patients with type 2 diabetes. | Imamura M et al. | β | 2021 | β |
| Genome-wide association studies in Samoans give insight into the genetic architecture of fasting serum lipid levels. | Carlson JC et al. | β | 2021 | β |
| Genome-wide association studies of low back pain and lumbar spinal disorders using electronic health record data identify a locus associated with lumbar spinal stenosis. | Suri P et al. | β | 2021 | β |
| Genome-Wide Association Studies of Schizophrenia and Bipolar Disorder in a Diverse Cohort of US Veterans. | Bigdeli TB et al. | β | 2021 | β |
| Genome-wide Association Studies Reveal Novel Locus With Sex-/Therapy-Specific Fracture Risk Effects in Childhood Cancer Survivors. | Im C et al. | β | 2021 | β |
| Genome-wide Association Study and Meta-analysis on Alcohol-Associated Liver Cirrhosis Identifies Genetic Risk Factors. | Schwantes-An TH et al. | β | 2021 | β |
| Genome-wide association study followed by trans-ancestry meta-analysis identify 17 new risk loci for schizophrenia. | Liu J et al. | β | 2021 | β |
| Genome-Wide Association Study (GWAS) of dental caries in diverse populations. | Alotaibi RN et al. | β | 2021 | β |
| Genome-wide Association Study Identifies 2 New Loci Associated With Anti-NMDAR Encephalitis. | Tietz AK et al. | β | 2021 | β |
| Genome-Wide Association Study Identifies a Functional <i>SIDT2</i> Variant Associated With HDL-C (High-Density Lipoprotein Cholesterol) Levels and Premature Coronary Artery Disease. | LeΓ³n-Mimila P et al. | β | 2021 | β |
| Genome-wide association study identifies a novel maternal geneβΓβstress interaction associated with spontaneous preterm birth. | Hong X et al. | β | 2021 | β |
| Genome-wide association study identifies BTNL2 associated with atopic asthma in children. | Kim SY et al. | β | 2021 | β |
| Genome wide association study identifies four loci for early onset schizophrenia. | Guo S et al. | β | 2021 | β |
| Genome-wide association study identifies novel susceptibility loci for KIT D816V positive mastocytosis. | GalatΓ G et al. | β | 2021 | β |
| Genome-Wide Association Study Identifies Risk Loci for Cluster Headache. | O'Connor E et al. | β | 2021 | β |
| Genome-wide association study in the Taiwan Biobank identifies four novel genes for human height: NABP2, RASA2, RNF41 and SLC39A5. | Lin E et al. | β | 2021 | β |
| Genome-Wide Association Study Meta-Analysis for Parkinson Disease Motor Subtypes. | Alfradique-Dunham I et al. | β | 2021 | β |
| Genome-Wide Association Study of 2,093 Cases With Idiopathic Polyneuropathy and 445,256 Controls Identifies First Susceptibility Loci. | Winsvold BS et al. | β | 2021 | β |
| Genome-wide association study of asthma, total IgE, and lung function in a cohort of Peruvian children. | Akenroye AT et al. | β | 2021 | β |
| Genome-wide association study of cardiac troponin I in the general population. | Moksnes MR et al. | β | 2021 | β |
| Genome-wide association study of fish oil supplementation on lipid traits in 81,246 individuals reveals new gene-diet interaction loci. | Francis M et al. | β | 2021 | β |
| Genome-wide association study of phenotypes measuring progression from first cocaine or opioid use to dependence reveals novel risk genes. | Sherva R et al. | β | 2021 | β |
| Genome-wide association study of resistance to Mycobacterium tuberculosis infection identifies a locus at 10q26.2 in three distinct populations. | Quistrebert J et al. | β | 2021 | β |
| Genome-wide association study of serum metabolites in the African American Study of Kidney Disease and Hypertension. | Luo S et al. | β | 2021 | β |
| Genome-wide association study reveals an association between the HLA-DPB1<sup>β</sup>02:01:02 allele and wheat-dependent exercise-induced anaphylaxis. | Fukunaga K et al. | β | 2021 | β |
| Genome-wide discovery of genetic loci that uncouple excess adiposity from its comorbidities. | Huang LO et al. | β | 2021 | β |
| Genome-Wide Gene-by-Smoking Interaction Study of Chronic Obstructive Pulmonary Disease. | Kim W et al. | β | 2021 | β |
| Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries. | Gharahkhani P et al. | β | 2021 | β |
| Genome-Wide Meta-analysis Identifies Genetic Variants Associated With Glycemic Response to Sulfonylureas. | Dawed AY et al. | β | 2021 | β |
| Genomic Analysis of Germline Variation Associated with Survival of Patients with Colorectal Cancer Treated with Chemotherapy Plus Biologics in CALGB/SWOG 80405 (Alliance). | Innocenti F et al. | β | 2021 | β |
| Genomic atlas of the proteome from brain, CSF and plasma prioritizes proteins implicated in neurological disorders. | Yang C et al. | β | 2021 | β |
| Germline genetic contribution to the immune landscape of cancer. | Sayaman RW et al. | β | 2021 | β |
| Germline variants are associated with increased primary melanoma tumor thickness at diagnosis. | Mangantig E et al. | β | 2021 | β |
| Germline variation in the insulin-like growth factor pathway and risk of Barrett's esophagus and esophageal adenocarcinoma. | Dighe SG et al. | β | 2021 | β |
| Glycosaminoglycan biosynthesis pathway in host genome is associated with Helicobacter pylori infection. | Hu D et al. | β | 2021 | β |
| GWAS Analysis of 17,019 Korean Women Identifies the Variants Associated with Facial Pigmented Spots. | Shin JG et al. | β | 2021 | β |
| GWAS for autoimmune Addison's disease identifies multiple risk loci and highlights AIRE in disease susceptibility. | Eriksson D et al. | β | 2021 | β |
| GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression. | Wu Y et al. | β | 2021 | β |
| GW-SEM 2.0: Efficient, Flexible, and Accessible Multivariate GWAS. | Pritikin JN et al. | β | 2021 | β |
| High-throughput framework forΒ genetic analyses of adverse drug reactions using electronic health records. | Zheng NS et al. | β | 2021 | β |
| Host genetics influences the relationship between the gut microbiome and psychiatric disorders. | Martins-Silva T et al. | β | 2021 | β |
| Host Genome-Wide Association Study of Infant Susceptibility to <i>Shigella</i>-Associated Diarrhea. | Duchen D et al. | β | 2021 | β |
| Human and rat skeletal muscle single-nuclei multi-omic integrative analyses nominate causal cell types, regulatory elements, and SNPs for complex traits. | Orchard P et al. | β | 2021 | β |
| <i>CDH12</i> as a Candidate Gene for Kidney Injury in Posterior Urethral Valve Cases: A Genome-wide Association Study Among Patients with Obstructive Uropathies. | van der Zanden LFM et al. | β | 2021 | β |
| Identification of a Novel Genetic Marker for Risk of Degenerative Rotator Cuff Disease Surgery in the UK Biobank. | Yanik EL et al. | β | 2021 | β |
| Identification of a Risk Locus at 7p22.3 for Schizophrenia and Bipolar Disorder in East Asian Populations. | Li W et al. | β | 2021 | β |
| Identification of pleiotropy at the gene level between psychiatric disorders and related traits. | Polushina T et al. | β | 2021 | β |
| Identification of susceptibility loci for cardiovascular disease in adults with hypertension, diabetes, and dyslipidemia. | Song Y et al. | β | 2021 | β |
| Identification of Three Loci Associated with Achilles Tendon Injury Risk from a Genome-wide Association Study. | Kim SK et al. | β | 2021 | β |
| Identifying drug targets for neurological and psychiatric disease via genetics and the brain transcriptome. | Baird DA et al. | β | 2021 | β |
| Insights into non-autoimmune type 1 diabetes with 13 novel loci in low polygenic risk score patients. | Qu J et al. | β | 2021 | β |
| Insights into the genetic architecture of the human face. | White JD et al. | β | 2021 | β |
| Integration of genetic, transcriptomic, and clinical data provides insight into 16p11.2 and 22q11.2 CNV genes. | Vysotskiy M et al. | β | 2021 | β |
| Integration of metabolomics, genomics, and immune phenotypes reveals the causal roles of metabolites in disease. | Chu X et al. | β | 2021 | β |
| Integrative analysis of genomic and epigenomic data reveal underlying superenhancer-mediated microRNA regulatory network for human bone mineral density. | Bai WY et al. | β | 2021 | β |
| Integrative genomics analysis reveals a 21q22.11 locus contributing risk to COVID-19. | Ma Y et al. | β | 2021 | β |
| <i>POLRMT</i> as a Novel Susceptibility Gene for Cardiotoxicity in Epirubicin Treatment of Breast Cancer Patients. | Velasco-Ruiz A et al. | β | 2021 | β |
| IRF7 and RNH1 are modifying factors of HIV-1 reservoirs: a genome-wide association analysis. | Zhang Z et al. | β | 2021 | β |
| <i>STXBP6</i> and <i>B3GNT6</i> Genes are Associated With Selective IgA Deficiency. | Lim CK et al. | β | 2021 | β |
| LocusZoom.js: interactive and embeddable visualization of genetic association study results. | Boughton AP et al. | β | 2021 | β |
| Looking for Sunshine: Genetic Predisposition to Sun Seeking in 265,000 Individuals of European Ancestry. | Sanna M et al. | β | 2021 | β |
| <i>SCFD1</i> expression quantitative trait loci in amyotrophic lateral sclerosis are differentially expressed. | Iacoangeli A et al. | β | 2021 | β |
| MRLocus: Identifying causal genes mediating a trait through Bayesian estimation of allelic heterogeneity. | Zhu A et al. | β | 2021 | β |
| Multiethnic Genome-Wide Association Study of Subclinical Atherosclerosis in Individuals With Type 2 Diabetes. | Lu Y et al. | β | 2021 | β |
| Multiple-ancestry genome-wide association study identifies 27 loci associated with measures of hemolysis following blood storage. | Page GP et al. | β | 2021 | β |
| Multi-trait association studies discover pleiotropic loci between Alzheimer's disease and cardiometabolic traits. | Bone WP et al. | β | 2021 | β |
| Multi-Trait Genome-Wide Association Study of Atherosclerosis Detects Novel Pleiotropic Loci. | Bellomo TR et al. | β | 2021 | β |
| Novel Alzheimer's disease risk variants identified based on whole-genome sequencing of APOE Ξ΅4 carriers. | Park JH et al. | β | 2021 | β |
| Novel genetic variants associated with brain functional networks in 18,445 adults from the UK Biobank. | Foo H et al. | β | 2021 | β |
| Novel risk factors for craniofacial microsomia and assessment of their utility in clinic diagnosis. | Xu X et al. | β | 2021 | β |
| Novel Risk Loci Associated With Genetic Risk for Bipolar Disorder Among Han Chinese Individuals: A Genome-Wide Association Study and Meta-analysis. | Li HJ et al. | β | 2021 | β |
| Omics data integration identifiesΒ ELOVL7Β andΒ MMDΒ gene regions as novel loci for adalimumab response in patients with Crohn's disease. | Gorenjak M et al. | β | 2021 | β |
| Performing post-genome-wide association study analysis: overview, challenges and recommendations. | Adam Y et al. | β | 2021 | β |
| Phenome risk classification enables phenotypic imputation and gene discovery in developmental stuttering. | Shaw DM et al. | β | 2021 | β |
| Pleiotropy method reveals genetic overlap between orofacial clefts at multiple novel loci from GWAS of multi-ethnic trios. | Ray D et al. | β | 2021 | β |
| Prediction of Alzheimer's disease using multi-variants from a Chinese genome-wide association study. | Jia L et al. | β | 2021 | β |
| Replication of HLA class II locus association with susceptibility to podoconiosis in three Ethiopian ethnic groups. | Gebresilase T et al. | β | 2021 | β |
| Search for a Functional Genetic Variant Mimicking the Effect of SGLT2 Inhibitor Treatment. | Wang S et al. | β | 2021 | β |
| Single-Cell RNA Sequencing in Parkinson's Disease. | Ma SX et al. | β | 2021 | β |
| Suitability of GWAS as a Tool to Discover SNPs Associated with Tick Resistance in Cattle: A Review. | Mkize N et al. | β | 2021 | β |
| Susceptibility loci and polygenic architecture highlight population specific and common genetic features in inguinal hernias: genetics in inguinal hernias. | Hikino K et al. | β | 2021 | β |
| Sweet Taste Preference: Relationships with Other Tastes, Liking for Sugary Foods and Exploratory Genome-Wide Association Analysis in Subjects with Metabolic Syndrome. | FernΓ‘ndez-CarriΓ³n R et al. | β | 2021 | β |
| The 3p21.31 genetic locus promotes progression to type 1 diabetes through the CCR2/CCL2 pathway. | Tran PM et al. | β | 2021 | β |
| The Effect of Common Variants in SLC44A2 on the Contribution to the Risk of Deep Cein Thrombosis after Orthopedic Surgery. | Zhi L et al. | β | 2021 | β |
| The influence of human genetic variation on Epstein-Barr virus sequence diversity. | RΓΌeger S et al. | β | 2021 | β |
| The morphometry of left cuneus mediating the genetic regulation on working memory. | He X et al. | β | 2021 | β |
| The PAX1 locus at 20p11 is a potential genetic modifier for bilateral cleft lip. | Curtis SW et al. | β | 2021 | β |
| The phytochemical hyperforin triggers thermogenesis in adipose tissue via a Dlat-AMPK signaling axis to curb obesity. | Chen S et al. | β | 2021 | β |
| Three genes associated with anterior and posterior cruciate ligament injury : a genome-wide association analysis. | Kim SK et al. | β | 2021 | β |
| Tractor uses local ancestry to enable the inclusion of admixed individuals in GWAS and to boost power. | Atkinson EG et al. | β | 2021 | β |
| Trans-ethnic genome-wide association study of severe COVID-19. | Wu P et al. | β | 2021 | β |
| Transporters, TBC1D4, and ARID5B Variants to Explain Glycated Hemoglobin Variability in Patients with Type 2 Diabetes. | Gonzalez-Covarrubias V et al. | β | 2021 | β |
| Using off-target data from whole-exome sequencing to improve genotyping accuracy, association analysis and polygenic risk prediction. | Dou J et al. | β | 2021 | β |
| Variation in the SERPINA6/SERPINA1 locus alters morning plasma cortisol, hepatic corticosteroid binding globulin expression, gene expression in peripheral tissues, and risk of cardiovascular disease. | Crawford AA et al. | β | 2021 | β |
| Weak Association Between the Glutamate Decarboxylase 1 Gene (GAD1) and Schizophrenia in Han Chinese Population. | Zhang L et al. | β | 2021 | β |
| WEVar: a novel statistical learning framework for predicting noncoding regulatory variants. | Wang Y et al. | β | 2021 | β |
| Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. | Thareja G et al. | β | 2021 | β |
| X-chromosome variants are associated with aldosterone producing adenomas. | Dutta RK et al. | β | 2021 | β |
| Adiponectin GWAS loci harboring extensive allelic heterogeneity exhibit distinct molecular consequences. | Spracklen CN et al. | β | 2020 | β |
| A genome-wide association study identifies FSHR rs2300441 associated with follicle-stimulating hormone levels. | Yan J et al. | β | 2020 | β |
| ALDH2 genotype modulates the association between alcohol consumption and AST/ALT ratio among middle-aged Japanese men: a genome-wide GβΓβE interaction analysis. | Sutoh Y et al. | β | 2020 | β |
| A multi-ethnic meta-analysis identifies novel genes, including ACSL5, associated with amyotrophic lateral sclerosis. | Nakamura R et al. | β | 2020 | β |
| A powerful and versatile colocalization test. | Deng Y et al. | β | 2020 | β |
| A shared genetic contribution to breast cancer and schizophrenia. | Lu D et al. | β | 2020 | β |
| Association analysis in a Latin American population revealed ethnic differences in rheumatoid arthritis-associated SNPs in Caucasian and Asian populations. | Castro-Santos P et al. | β | 2020 | β |
| Association Between Common Variants in RBFOX1, an RNA-Binding Protein, and Brain Amyloidosis in Early and Preclinical Alzheimer Disease. | Raghavan NS et al. | β | 2020 | β |
| Association of an <i>APBA3</i> Missense Variant with Risk of Premature Ovarian Failure in the Korean Female Population. | Park J et al. | β | 2020 | β |
| Associations between genetic variants of KIF5B, FMN1, and MGAT3 in the cadherin pathway and pancreatic cancer risk. | Zhao L et al. | β | 2020 | β |
| Associations of novel variants in <i>PIK3C3</i>, <i>INSR</i> and <i>MAP3K4</i> of the ATM pathway genes with pancreatic cancer risk. | Zhao LL et al. | β | 2020 | β |
| ATAC-Seq Reveals an <i>Isl1</i> Enhancer That Regulates Sinoatrial Node Development and Function. | Galang G et al. | β | 2020 | β |
| Candidate Gene Analysis Reveals Strong Association of <i>CETP</i> Variants With High Density Lipoprotein Cholesterol and <i>PCSK9</i> Variants With Low Density Lipoprotein Cholesterol in Ghanaian Adults: An AWI-Gen Sub-Study. | Agongo G et al. | β | 2020 | β |
| Chromosome 1q21.2 and additional loci influence risk of spontaneous coronary artery dissection and myocardial infarction. | Saw J et al. | β | 2020 | β |
| Common genetic variation in obesity, lipid transfer genes and risk of Metabolic Syndrome: Results from IDEFICS/I.Family study and meta-analysis. | Nagrani R et al. | β | 2020 | β |
| Common risk variants in NPHS1 and TNFSF15 are associated with childhood steroid-sensitive nephrotic syndrome. | Jia X et al. | β | 2020 | β |
| Common variation at 16p11.2 is associated with glycosuria in pregnancy: findings from a genome-wide association study in European women. | Lee MA et al. | β | 2020 | β |
| Complex genetic signatures in immune cells underlie autoimmunity and inform therapy. | OrrΓΉ V et al. | β | 2020 | β |
| Comprehensive genomic analysis of dietary habits in UK Biobank identifies hundreds of genetic associations. | Cole JB et al. | β | 2020 | β |
| Constant-severe pain in chronic pancreatitis is associated with genetic loci for major depression in the NAPS2 cohort. | Dunbar E et al. | β | 2020 | β |
| Constructing gene network for type 1 narcolepsy based on genome-wide association study and differential gene expression analysis (STROBE). | Ouyang H et al. | β | 2020 | β |
| Dissecting the Genetic Architecture of Cystatin C in Diversity Outbred Mice. | Huda MN et al. | β | 2020 | β |
| Effect of the <i>SIRT1</i> gene on regional cortical grey matter density in the Han Chinese population. | Rao S et al. | β | 2020 | β |
| Erosion of Gene Co-expression Networks Reveal Deregulation of Immune System Processes in Late-Onset Alzheimer's Disease. | Malamon JS et al. | β | 2020 | β |
| European genetic ancestry associated with risk of childhood ependymoma. | Zhang C et al. | β | 2020 | β |
| Exome-Wide Association Study Reveals Several Susceptibility Genes and Pathways Associated With Acute Coronary Syndromes in Han Chinese. | Zheng Q et al. | β | 2020 | β |
| Expanding the genetic architecture of nicotine dependence and its shared genetics with multiple traits. | Quach BC et al. | β | 2020 | β |
| Exploring and visualizing large-scale genetic associations by using PheWeb. | Gagliano Taliun SA et al. | β | 2020 | β |
| Family-based exome sequencing identifies rare coding variants in age-related macular degeneration. | Ratnapriya R et al. | β | 2020 | β |
| Four pleiotropic loci associated with fat mass and lean mass. | Liu Y et al. | β | 2020 | β |
| Genetic control of CCL24, POR, and IL23R contributes to the pathogenesis of sarcoidosis. | Meguro A et al. | β | 2020 | β |
| Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults. | Hofer E et al. | β | 2020 | β |
| Genetic Determinants of Reduced Arsenic Metabolism Efficiency in the 10q24.32 Region Are Associated With Reduced AS3MT Expression in Multiple Human Tissue Types. | Chernoff M et al. | β | 2020 | β |
| Genetic Regulation of Atherosclerosis-Relevant Phenotypes in Human Vascular Smooth Muscle Cells. | Aherrahrou R et al. | β | 2020 | β |
| Genetics of Gene Expression in the Aging Human Brain Reveal TDP-43 Proteinopathy Pathophysiology. | Yang HS et al. | β | 2020 | β |
| Genetic variants in PDSS1 and SLC16A6 of the ketone body metabolic pathway predict cutaneous melanoma-specific survival. | Dai W et al. | β | 2020 | β |
| Genetic Variation and Response to Neurocritical Illness: a Powerful Approach to Identify Novel Pathophysiological Mechanisms and Therapeutic Targets. | Acosta JN et al. | β | 2020 | β |
| Genome-Wide Association for HbA1c in Malay Identified Deletion on SLC4A1 that Influences HbA1c Independent of Glycemia. | Chai JF et al. | β | 2020 | β |
| Genome-wide association studies and heritability analysis reveal the involvement of host genetics in the Japanese gut microbiota. | Ishida S et al. | β | 2020 | β |
| Genome-wide association studies of antidepressant class response and treatment-resistant depression. | Li QS et al. | β | 2020 | β |
| Genome-wide association study and polygenic risk score analysis of esketamine treatment response. | Li QS et al. | β | 2020 | β |
| Genome-wide association study for circulating fibroblast growth factor 21 and 23. | Chuang GT et al. | β | 2020 | β |
| Genome-wide association study identifies 16 genomic regions associated with circulating cytokines at birth. | Wang Y et al. | β | 2020 | β |
| Genome-wide association study identifies genetic factors that modify age at onset in Machado-Joseph disease. | AkΓ§imen F et al. | β | 2020 | β |
| Genome-wide association study identifies zonisamide responsive gene in Parkinson's disease patients. | Cha PC et al. | β | 2020 | β |
| Genome-Wide Association Study in 3,173 Outbred Rats Identifies Multiple Loci for Body Weight, Adiposity, and Fasting Glucose. | Chitre AS et al. | β | 2020 | β |
| Genome-Wide Association Study in Asians Identifies Novel Loci for High Myopia and Highlights a Nervous System Role in Its Pathogenesis. | Meguro A et al. | β | 2020 | β |
| Genomewide Association Study of Acute Anterior Uveitis Identifies New Susceptibility Loci. | Huang XF et al. | β | 2020 | β |
| Genome-wide association study of cafΓ©-au-lait macule number in neurofibromatosis type 1. | Sung H et al. | β | 2020 | β |
| Genome-wide association study of smoking trajectory and meta-analysis of smoking status in 842,000 individuals. | Xu K et al. | β | 2020 | β |
| Genome-wide association study of the TP53 R249S mutation in hepatocellular carcinoma with aflatoxin B1 exposure and infection with hepatitis B virus. | Han C et al. | β | 2020 | β |
| Genomewide Meta-Analysis Validates a Role for S1PR1 in Microtubule Targeting Agent-Induced Sensory Peripheral Neuropathy. | Chua KC et al. | β | 2020 | β |
| Genomic Regions 10q22.2, 17q21.31, and 2p23.1 Can Contribute to a Lower Lung Function in African Descent Populations. | Fonseca H et al. | β | 2020 | β |
| H2A Histone Family Member X (H2AX) Is Upregulated in Ovarian Cancer and Demonstrates Utility as a Prognostic Biomarker in Terms of Overall Survival. | Saravi S et al. | β | 2020 | β |
| Host Genetic Factors Associated with Vaginal Microbiome Composition in Kenyan Women. | Mehta SD et al. | β | 2020 | β |
| Identification of 31 loci for mammographic density phenotypes and their associations with breast cancer risk. | Sieh W et al. | β | 2020 | β |
| Identification of a functional human-unique 351-bp Alu insertion polymorphism associated with major depressive disorder in the 1p31.1 GWAS risk loci. | Liu W et al. | β | 2020 | β |
| Identification of Novel Alzheimer's Disease Loci Using Sex-Specific Family-Based Association Analysis of Whole-Genome Sequence Data. | Prokopenko D et al. | β | 2020 | β |
| Impact of genetic polymorphisms in kinetochore and spindle assembly genes on chromosomal aberration frequency in healthy humans. | Niazi Y et al. | β | 2020 | β |
| Inclusion of endophenotypes in a standard GWAS facilitate a detailed mechanistic understanding of genetic elements that control blood lipid levels. | Zhang Q et al. | β | 2020 | β |
| Influence of Genetic Variance on Biomarker Levels After Occupational Exposure to 1,6-Hexamethylene Diisocyanate Monomer and 1,6-Hexamethylene Diisocyanate Isocyanurate. | Taylor LW et al. | β | 2020 | β |
| IntAssoPlot: An R Package for Integrated Visualization of Genome-Wide Association Study Results With Gene Structure and Linkage Disequilibrium Matrix. | He F et al. | β | 2020 | β |
| Integrating Mouse and Human Genetic Data to Move beyond GWAS and Identify Causal Genes in Cholesterol Metabolism. | Li Z et al. | β | 2020 | β |
| Investigating the influence of mtDNA and nuclear encoded mitochondrial variants on high intensity interval training outcomes. | Harvey NR et al. | β | 2020 | β |
| Lack of Association Between Genetic Variants at <i>ACE2</i> and <i>TMPRSS2</i> Genes Involved in SARS-CoV-2 Infection and Human Quantitative Phenotypes. | Lopera Maya EA et al. | β | 2020 | β |
| Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. | Ishigaki K et al. | β | 2020 | β |
| Linking protein to phenotype with Mendelian Randomization detects 38 proteins with causal roles in human diseases and traits. | Bretherick AD et al. | β | 2020 | β |
| LocusFocus: Web-based colocalization for the annotation and functional follow-up of GWAS. | Panjwani N et al. | β | 2020 | β |
| Looking into the genetic bases of OCD dimensions: a pilot genome-wide association study. | Alemany-Navarro M et al. | β | 2020 | β |
| <i>APOB</i> Genotypes and <i>CDH13</i> Haplotypes in the Cholesterol-Related Pathway Genes Predict Non-Small Cell Lung Cancer Survival. | Deng W et al. | β | 2020 | β |
| Lung Function in African American Children with Asthma Is Associated with Novel Regulatory Variants of the KIT Ligand <i>KITLG/SCF</i> and Gene-By-Air-Pollution Interaction. | Mak ACY et al. | β | 2020 | β |
| Meta-analysis of genome-wide association study identifies FBN2 as a novel locus associated with systemic lupus erythematosus in Thai population. | Tangtanatakul P et al. | β | 2020 | β |
| Modeling of variables in cellularΒ infection reveals CXCL10 levels are regulated by human genetic variation and the Chlamydia-encoded CPAF protease. | Schott BH et al. | β | 2020 | β |
| Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction. | Ntalla I et al. | β | 2020 | β |
| Multi-ethnic transcriptome-wide association study of prostate cancer. | Fiorica PN et al. | β | 2020 | β |
| Multiple independent mechanisms link gene polymorphisms in the region of ZEB2 with risk of coronary artery disease. | Ma L et al. | β | 2020 | β |
| Muscle-Liver Trafficking of BCAA-Derived Nitrogen Underlies Obesity-Related Glycine Depletion. | White PJ et al. | β | 2020 | β |
| NG-Circos: next-generation Circos for data visualization and interpretation. | Cui Y et al. | β | 2020 | β |
| Novel genetic risk factors influence progression of islet autoimmunity to type 1 diabetes. | Onengut-Gumuscu S et al. | β | 2020 | β |
| Novel Risk Loci in Tinnitus and Causal Inference With Neuropsychiatric Disorders Among Adults of European Ancestry. | Clifford RE et al. | β | 2020 | β |
| Novel Variants of <i>ELP2</i> and <i>PIAS1</i> in the Interferon Gamma Signaling Pathway Are Associated with Non-Small Cell Lung Cancer Survival. | Zhao YC et al. | β | 2020 | β |
| Pharmacogenomics Study for Raloxifene in Postmenopausal Female with Osteoporosis. | Lu HF et al. | β | 2020 | β |
| PheGWAS: a new dimension to visualize GWAS across multiple phenotypes. | George G et al. | β | 2020 | β |
| Pleiotropic Locus 15q24.1 Reveals a Gender-Specific Association with Neovascular but Not Atrophic Age-Related Macular Degeneration (AMD). | Kiel C et al. | β | 2020 | β |
| Profiles of histidine-rich glycoprotein associate with age and risk of all-cause mortality. | Hong MG et al. | β | 2020 | β |
| Quantitative genome-wide association analyses of receptive language in the Danish High Risk and Resilience Study. | Nudel R et al. | β | 2020 | β |
| Sequence Variants in TAAR5 and Other Loci Affect Human Odor Perception and Naming. | Gisladottir RS et al. | β | 2020 | β |
| Shared genetic background between children and adults with attention deficit/hyperactivity disorder. | Rovira P et al. | β | 2020 | β |
| Skeletal muscle enhancer interactions identify genes controlling whole-body metabolism. | Williams K et al. | β | 2020 | β |
| sn-spMF: matrix factorization informs tissue-specific genetic regulation of gene expression. | He Y et al. | β | 2020 | β |
| Studies of human twins reveal genetic variation that affects dietary fat perception. | Lin C et al. | β | 2020 | β |
| SZDB2.0: an updated comprehensive resource for schizophrenia research. | Wu Y et al. | β | 2020 | β |
| The association between circulating 25-hydroxyvitamin D metabolites and type 2 diabetes in European populations: AΒ meta-analysis and Mendelian randomisation analysis. | Zheng JS et al. | β | 2020 | β |
| The genetic basis for the inverse relationship between rheumatoid arthritis and schizophrenia. | Zamanpoor M et al. | β | 2020 | β |
| The genetics of circulating BDNF: towards understanding the role of BDNF in brain structure and function in middle and old ages. | Li S et al. | β | 2020 | β |
| The Human Leukocyte Antigen Locus and Rheumatic Heart Disease Susceptibility in South Asians and Europeans. | Auckland K et al. | β | 2020 | β |
| The <i>FAM171A2</i> gene is a key regulator of progranulin expression and modifies the risk of multiple neurodegenerative diseases. | Xu W et al. | β | 2020 | β |
| The Parkinson's Disease Genome-Wide Association Study Locus Browser. | Grenn FP et al. | β | 2020 | β |
| The shaping of immunological responses through natural selection after the Roma Diaspora. | Dobon B et al. | β | 2020 | β |
| The TAGA Study: A Study of Factors Determining Aortic Diameter in Families at High Risk of Abdominal Aortic Aneurysm Reveal Two New Candidate Genes. | Peypoch O et al. | β | 2020 | β |
| Treatment- and population-specific genetic risk factors for anti-drug antibodies against interferon-beta: a GWAS. | Andlauer TFM et al. | β | 2020 | β |
| Two novel pleiotropic loci associated with osteoporosis and abdominal obesity. | Liu L et al. | β | 2020 | β |
| Urine 6-Bromotryptophan: Associations with Genetic Variants and Incident End-Stage Kidney Disease. | Sekula P et al. | β | 2020 | β |
| Validating a non-invasive, ALT-based non-alcoholic fatty liver phenotype in the million veteran program. | Serper M et al. | β | 2020 | β |
| Variants in <i>PPP2R2B</i> and <i>IGF2BP3</i> are associated with higher tau deposition. | Ramanan VK et al. | β | 2020 | β |
| Variants in <i>SNAI1</i>, <i>AMDHD1</i> and <i>CUBN</i> in vitamin D pathway genes are associated with breast cancer risk: a large-scale analysis of 14 GWASs in the DRIVE study. | Wang H et al. | β | 2020 | β |
| Volumetric GWAS of medial temporal lobe structures identifies an ERC1 locus using ADNI high-resolution T2-weighted MRI data. | Cong S et al. | β | 2020 | β |
| Whole blood co-expression modules associate with metabolic traits and type 2 diabetes: an IMI-DIRECT study. | Gudmundsdottir V et al. | β | 2020 | β |
| Whole-Genome and RNA Sequencing Reveal Variation and Transcriptomic Coordination in the Developing Human Prefrontal Cortex. | Werling DM et al. | β | 2020 | β |