stress risk_factor_for depression

which can also contribute to ... internalizing outcomes such as depression

Strong GxE tests documenting that stress antedated depression exist

individuals ... develop depression after life stress and in response to it

temporal order between cause (stress) and effect (depression)

Results showed empirically that unless the stress occurred before the depression, the GxE finding was not observed.

similar to the literature surrounding the experience of stressful life events and the onset of depression

prevent depression developed under environmental changes, such as stress.

prevent depression developed under environmental changes, such as stress