Chrnb3 associated_with nicotine
Evidence from:
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Evidence (9 sources)
Identification of CHRNA5 rare variants in African-American heavy smokers.
(2014)
PMID:24682045
cited
association of rare variants in CHRNB3 ... with nicotine dependence
confidence: 0.95
Pharmacogenetics of smoking cessation: role of nicotine target and metabolism genes.
(2012)
PMID:22290489
cited
SNPs in the genes encoding the α6 and β3 subunits, CHRNA6 and CHRNB3, are associated with nicotine dependence...
confidence: 0.96
Pharmacogenetics of smoking cessation: role of nicotine target and metabolism genes.
(2012)
PMID:22290489
cited
elucidate their roles in nicotine dependence
confidence: 0.85
Multiple cholinergic nicotinic receptor genes affect nicotine dependence risk in African and European Americans.
(2010)
PMID:20584212
cited
Evidence for association was observed ... for the CHRNB3-CHRNA6 ... in the development of nicotine dependence.
confidence: 0.95
Multiple cholinergic nicotinic receptor genes affect nicotine dependence risk in African and European Americans.
(2010)
PMID:20584212
cited
associated with nicotine dependence ... in several European-ancestry samples
confidence: 0.95
Multiple cholinergic nicotinic receptor genes affect nicotine dependence risk in African and European Americans.
(2010)
PMID:20584212
cited
The region upstream of the CHRNB3-CHRNA6 cluster has been associated with nicotine dependence ...
confidence: 0.70
KO mice for nAChR subunits ... β2–β4 have shown that the deletion of these genes alters many effects of nicotine.
confidence: 0.90
Association of a single nucleotide polymorphism in neuronal acetylcholine receptor subunit alpha 5 (CHRNA5) with smoking status and with 'pleasurable buzz' during early experimentation with smoking.
(2008)
PMID:18783506
cited
early smoking experiences may mediate nicotine dependence, possibly also ... beta-3 subunits
confidence: 0.80
Nicotinic acetylcholine receptor beta2 subunit gene implicated in a systems-based candidate gene study of smoking cessation.
(2008)
PMID:18593715
cited
associations of SNPs in ... nAChR subunit genes with nicotine dependence
confidence: 0.80