Twin cohort associated_with Alcohol Use Disorder

Evidence from: primary | all sources

Evidence (14 sources)

robust evidence from twin ... studies indicate that genetic influences also operate “beyond the skin” to shape the environment

confidence: 0.90

A study of twin pairs with genomic data estimated that the SNP‑based heritability of AUD was 33% (se=0.12).

confidence: 0.96

If significant, this would indicate that at least partially different genetic factors culminate in AUD in males and females

confidence: 0.80

based on 13 twin ... studies was 0.49 (95% CI 0.47–0.54)

confidence: 0.90

We searched ... for all twin ... studies of AUD.

confidence: 0.94

the twin studies that we examined ... assessed AUDs via personal interviews ... used registry information

confidence: 0.90

The combined estimate of the heritability of AUDs in the twin studies was 0.51 [95% confidence interval (CI) 0.45–0.56].

confidence: 0.96

estimates of genetic and shared environmental variance in liability to AUD ... derived from twin studies

confidence: 0.93

twin ... studies utilized personal interviews ... to assess AUD

confidence: 0.85

Shared environmental influences on AUD were found in a twin study that used data from twins who had been hospitalized for alcoholism...

confidence: 0.90

uses the natural contrast between dizygotic (DZ) twins ... to estimate genetic ... influences on behavior ... risk for AUD

confidence: 0.90

Shared environmental influences on AUD in male twins were detected

confidence: 0.90

evidence for heritability from twin studies for a given outcome ...

confidence: 0.90

A large scale twin study did not find a significant gender difference in genetic variance in AUD

confidence: 0.85