Δ9-THC targets CB1 receptor

Subject: Δ9-THC
Relation: targets
Object: CB1 receptor
p-value: —

Evidence from: primary | all sources

Evidence (6 sources)

Cannabis and psychosis/schizophrenia: human studies. (2009) PMID:19609589 cited

Acute injection of Δ9-THC ... stimulating CB1R

confidence: 0.90

Cannabis and psychosis/schizophrenia: human studies. (2009) PMID:19609589 cited

The effects of Δ9-THC are mediated by agonist/partial agonist effects at CB1 receptors (CB1R)

confidence: 0.96

Hippocampal CB(1) receptors mediate the memory impairing effects of Delta(9)-tetrahydrocannabinol. (2009) PMID:19322169 cited

global CB1 receptor knockout mice are resistant to the effects of Δ9-THC ... indicates that this receptor is predominantly responsible for the CNS effects of marijuana.

confidence: 0.96

Hippocampal CB(1) receptors mediate the memory impairing effects of Delta(9)-tetrahydrocannabinol. (2009) PMID:19322169 cited

Δ9-THC impairs memory function through a direct action of CB1 receptors

confidence: 0.96

Hippocampal CB(1) receptors mediate the memory impairing effects of Delta(9)-tetrahydrocannabinol. (2009) PMID:19322169 cited

CB1 receptors in the hippocampus play a necessary role in Δ9-THC‑induced memory impairment.

confidence: 0.95

Hippocampal CB(1) receptors mediate the memory impairing effects of Delta(9)-tetrahydrocannabinol. (2009) PMID:19322169 cited

CB1 receptors ... may be the primary target of Δ9-THC in the hippocampus

confidence: 0.93