Polymorphisms in MHC2TA, SOCS1, KIAA0350 and PTPN2 were identified by resequencing 32 CEPH DNA samples (from Utah residents with northern and western European ancestry) in common with HapMap14. The sequencing reactions were performed using Applied Biosystems' BigDye (version 3.1) chemistry and the sequences resolved using an ABI 3700 Genetic Analyzer. Analyses of the sequence traces were performed using the Staden package, and traces were scored independently by a second operator by hand. Annotations for MHC2TA, SOCS1, KIAA0350 and PTPN2 are available from T1DBase (available only from the UK mirror site; see URLs below), together with sequence and polymorphism data the T1DBase PosterPages (see URL below) . For IL2 and IL21 and the flanking regions, polymorphisms were identified by resequencing samples from 32 individuals with T1D.
