As a secondary analysis, we look up 102 and 5 validated SNVs from the GWAS and exome analyses, respectively, in non-European ancestry samples. These comprise analysis of East Asian (N = 31,513) and South Asian (N = 33,115) ancestry data from the iGEN-BP consortium11 for the GWAS lookups, and South Asian (N = 25,937), African American (N = 21,488) and Hispanic (N = 4,581) ancestry data from the CHARGE BP exome consortium10 and CHD+ Exome consortium9, for the exome content lookups (Supplementary Note). We carry out a binomial (sign) test based on the number of SNVs with consistent directions of effect between UKB and each of the non-European ancestry samples.