MANCOVA using age as covariate revealed a significant main effect of age [F(2,79) = 2.6, p = 0.043] and group [F(2,79) = 6.95, p < 0.001] for CSF volumes. Significant group effects were observed for total sulcal CSF [f(2,79) = 7.33, p = 0.001], fCSF [F(2,79) = 10.90, p < 0.001) and tCSF [F(2,79) = 18.52, p < 0.001]. Pairwise comparisons showed that ALC had more total sulcal CSF in these regions than both LD and PSU (see Table 3). PSU had similar sulcal CSF volumes than LD, except for the temporal lobe, where PSU had less CSF than LD. Ventricular CSF volumes were comparable among all three groups. Lobar CSF volumes did not correlate significantly with the corresponding lobar WM volumes.