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Chunk #9 — Materials and methods — Dependent Measures

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COMT Val158Met modulates subjective responses to intravenous nicotine and cognitive performance in abstinent smokers.
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reflecting nicotine deprivation levels (37, 38). The MNWS measures withdrawal symptoms from tobacco and includes items to assess cigarette craving, irritability/anger, anxiety, difficulty concentrating, restlessness, increased appetite, depressed or sad mood, and insomnia (39, 40). The PANAS is a 20-item scale, which assesses both negative and positive affective states (41). The BQSU, MNWS and PANAS were administered before and after the session.