Samples were supplied from multiple investigators from different institutions with approval from their respective institutional review boards (IRBs). All study participants provided written consent prior to study enrolment; consent forms were obtained at each location under IRB guidelines. Samples were then assembled at the Oklahoma Medical Research Foundation (OMRF) and the study protocols (including the enrollment process, consent forms, collection of DNA and subject information) for this study were approved by the Oklahoma Medical Research Foundation (OMRF) Institutional Review Board.
